diff --git a/bootstrap/handlers/httpserver.go b/bootstrap/handlers/httpserver.go
index d56f9425..79f10850 100644
--- a/bootstrap/handlers/httpserver.go
+++ b/bootstrap/handlers/httpserver.go
@@ -1,6 +1,6 @@
 /*******************************************************************************
  * Copyright 2019 Dell Inc.
- * Copyright 2021 IOTech Ltd
+ * Copyright 2021-2022 IOTech Ltd
  *
  * Licensed under the Apache License, Version 2.0 (the "License"); you may not use this file except
  * in compliance with the License. You may obtain a copy of the License at
@@ -17,6 +17,11 @@ package handlers
 
 import (
 	"context"
+	"encoding/json"
+	"fmt"
+	"github.com/edgexfoundry/go-mod-core-contracts/v2/clients/logger"
+	"github.com/edgexfoundry/go-mod-core-contracts/v2/common"
+	commonDTO "github.com/edgexfoundry/go-mod-core-contracts/v2/dtos/common"
 	"net/http"
 	"strconv"
 	"sync"
@@ -98,6 +103,9 @@ func (b *HttpServer) BootstrapHandler(
 	b.router.Use(func(next http.Handler) http.Handler {
 		return http.TimeoutHandler(next, timeout, "HTTP request timeout")
 	})
+
+	b.router.Use(RequestLimitMiddleware(bootstrapConfig.Service.MaxRequestSize, lc))
+
 	b.router.Use(ProcessCORS(bootstrapConfig.Service.CORSConfiguration))
 
 	// handle the CORS preflight request
@@ -142,3 +150,30 @@ func (b *HttpServer) BootstrapHandler(
 
 	return true
 }
+
+// RequestLimitMiddleware is a middleware function that limits the request body size to Service.MaxRequestSize in kilobytes
+func RequestLimitMiddleware(sizeLimit int64, lc logger.LoggingClient) func(http.Handler) http.Handler {
+	return func(next http.Handler) http.Handler {
+		return http.HandlerFunc(func(w http.ResponseWriter, r *http.Request) {
+			switch r.Method {
+			case http.MethodPost, http.MethodPut, http.MethodPatch:
+				if sizeLimit > 0 && r.ContentLength > sizeLimit*1024 {
+					response := commonDTO.NewBaseResponse("", fmt.Sprintf("request size exceed Service.MaxRequestSize(%d KB)", sizeLimit), http.StatusRequestEntityTooLarge)
+					lc.Errorf(response.Message)
+
+					w.Header().Set(common.ContentType, common.ContentTypeJSON)
+					w.WriteHeader(response.StatusCode)
+					if err := json.NewEncoder(w).Encode(response); err != nil {
+						lc.Errorf("Error encoding the data:  %v", err)
+						http.Error(w, err.Error(), http.StatusInternalServerError)
+					}
+				} else {
+					next.ServeHTTP(w, r)
+				}
+			default:
+				// ignore the other http methods because they do not have request bodies
+				next.ServeHTTP(w, r)
+			}
+		})
+	}
+}
diff --git a/bootstrap/handlers/httpserver_test.go b/bootstrap/handlers/httpserver_test.go
new file mode 100644
index 00000000..9465ecad
--- /dev/null
+++ b/bootstrap/handlers/httpserver_test.go
@@ -0,0 +1,57 @@
+//
+// Copyright (C) 2022 IOTech Ltd
+//
+// SPDX-License-Identifier: Apache-2.0
+
+package handlers
+
+import (
+	"encoding/json"
+	"github.com/edgexfoundry/go-mod-core-contracts/v2/clients/logger"
+	"github.com/edgexfoundry/go-mod-core-contracts/v2/common"
+	commonDTO "github.com/edgexfoundry/go-mod-core-contracts/v2/dtos/common"
+	"github.com/stretchr/testify/assert"
+	"github.com/stretchr/testify/require"
+	"net/http"
+	"net/http/httptest"
+	"strings"
+	"testing"
+)
+
+func TestRequestLimitMiddleware(t *testing.T) {
+	lc := logger.NewMockClient()
+	payload := make([]byte, 2048)
+	tests := []struct {
+		name          string
+		sizeLimit     int64
+		errorExpected bool
+	}{
+		{"Valid unlimited size", int64(0), false},
+		{"Valid size", int64(2), false},
+		{"Invalid size", int64(1), true},
+	}
+
+	for _, testCase := range tests {
+		middleware := RequestLimitMiddleware(testCase.sizeLimit, lc)
+		handler := middleware(http.HandlerFunc(func(w http.ResponseWriter, r *http.Request) {}))
+
+		reader := strings.NewReader(string(payload))
+		req, err := http.NewRequest(http.MethodPost, "/", reader)
+		require.NoError(t, err)
+
+		recorder := httptest.NewRecorder()
+		handler.ServeHTTP(recorder, req)
+		resp := recorder.Result()
+
+		if testCase.errorExpected {
+			var res commonDTO.BaseResponse
+			err = json.Unmarshal(recorder.Body.Bytes(), &res)
+			require.NoError(t, err)
+
+			assert.Equal(t, http.StatusRequestEntityTooLarge, resp.StatusCode, "http status code is not as expected")
+			assert.Equal(t, common.ContentTypeJSON, resp.Header.Get(common.ContentType), "http header Content-Type is not as expected")
+			assert.Equal(t, http.StatusRequestEntityTooLarge, int(res.StatusCode), "Response status code not as expected")
+			assert.NotEmpty(t, res.Message, "Response message doesn't contain the error message")
+		}
+	}
+}
diff --git a/config/types.go b/config/types.go
index 83a588e3..aa5d23c8 100644
--- a/config/types.go
+++ b/config/types.go
@@ -43,7 +43,7 @@ type ServiceInfo struct {
 	// MaxResultCount specifies the maximum size list supported
 	// in response to REST calls to other services.
 	MaxResultCount int
-	// MaxRequestSize defines the maximum size of http request body in bytes
+	// MaxRequestSize defines the maximum size of http request body in kilobytes
 	MaxRequestSize int64
 	// RequestTimeout specifies a timeout (in milliseconds) for
 	// processing REST request calls from other services.