diff --git a/src/libraries/System.Net.Http/tests/FunctionalTests/HttpClientHandlerTest.Http2.cs b/src/libraries/System.Net.Http/tests/FunctionalTests/HttpClientHandlerTest.Http2.cs
index 040558f36bfcd..12db501f35728 100644
--- a/src/libraries/System.Net.Http/tests/FunctionalTests/HttpClientHandlerTest.Http2.cs
+++ b/src/libraries/System.Net.Http/tests/FunctionalTests/HttpClientHandlerTest.Http2.cs
@@ -1657,6 +1657,7 @@ public static IEnumerable<object[]> KeepAliveTestDataSource()
         [OuterLoop("Significant delay.")]
         [MemberData(nameof(KeepAliveTestDataSource))]
         [ConditionalTheory(nameof(SupportsAlpn))]
+        [ActiveIssue("https://github.com/dotnet/runtime/issues/41929")]
         public async Task Http2_PingKeepAlive(TimeSpan keepAlivePingDelay, HttpKeepAlivePingPolicy keepAlivePingPolicy, bool expectRequestFail)
         {
             TimeSpan pingTimeout = TimeSpan.FromSeconds(5);