diff --git a/src/libraries/System.Resources.Extensions/tests/BinaryFormatTests/Common/BasicObjectTests.cs b/src/libraries/System.Resources.Extensions/tests/BinaryFormatTests/Common/BasicObjectTests.cs
index b00cbfa5f75f7..b38235fa86ce2 100644
--- a/src/libraries/System.Resources.Extensions/tests/BinaryFormatTests/Common/BasicObjectTests.cs
+++ b/src/libraries/System.Resources.Extensions/tests/BinaryFormatTests/Common/BasicObjectTests.cs
@@ -14,6 +14,7 @@ public abstract class BasicObjectTests<T> : SerializationTest<T> where T : ISeri
 
     [Theory]
     [MemberData(nameof(SerializableObjects))]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/105020", typeof(PlatformDetection), nameof(PlatformDetection.IsMonoRuntime), nameof(PlatformDetection.IsPpc64leProcess))]
     public void DeserializeStoredObjects(object value, TypeSerializableValue[] serializedData)
     {
         // Following call may change the contents of the fields by invoking lazy-evaluated properties.
diff --git a/src/libraries/System.Resources.Extensions/tests/BinaryFormatTests/Legacy/BinaryFormatterTests.cs b/src/libraries/System.Resources.Extensions/tests/BinaryFormatTests/Legacy/BinaryFormatterTests.cs
index fbd0544153a76..59cd5a2a0c76f 100644
--- a/src/libraries/System.Resources.Extensions/tests/BinaryFormatTests/Legacy/BinaryFormatterTests.cs
+++ b/src/libraries/System.Resources.Extensions/tests/BinaryFormatTests/Legacy/BinaryFormatterTests.cs
@@ -20,6 +20,7 @@ public partial class BinaryFormatterTests
 {
     [Theory]
     [MemberData(nameof(SerializableObjects_MemberData))]
+    [ActiveIssue("https://github.com/dotnet/runtime/issues/105020", typeof(PlatformDetection), nameof(PlatformDetection.IsMonoRuntime), nameof(PlatformDetection.IsPpc64leProcess))]
     public void ValidateAgainstBlobs(object obj, TypeSerializableValue[] blobs)
         => ValidateAndRoundtrip(obj, blobs, isEqualityComparer: false);
 
diff --git a/src/libraries/System.Runtime.Serialization.Formatters/tests/BinaryFormatterTests.cs b/src/libraries/System.Runtime.Serialization.Formatters/tests/BinaryFormatterTests.cs
index 4587f3e47b1fa..1653251700135 100644
--- a/src/libraries/System.Runtime.Serialization.Formatters/tests/BinaryFormatterTests.cs
+++ b/src/libraries/System.Runtime.Serialization.Formatters/tests/BinaryFormatterTests.cs
@@ -67,7 +67,7 @@ public void ValidateBasicObjectsRoundtrip(object obj, FormatterAssemblyStyle ass
 
         [Theory]
         [SkipOnCoreClr("Takes too long on Checked", ~RuntimeConfiguration.Release)]
-        [ActiveIssue("https://github.com/mono/mono/issues/15115", TestRuntimes.Mono)]
+        [ActiveIssue("https://github.com/dotnet/runtime/issues/105020", typeof(PlatformDetection), nameof(PlatformDetection.IsMonoRuntime), nameof(PlatformDetection.IsPpc64leProcess))]
         [MemberData(nameof(SerializableObjects_MemberData))]
         public void ValidateAgainstBlobs(object obj, TypeSerializableValue[] blobs)
             => ValidateAndRoundtrip(obj, blobs, false);