diff --git a/eng/pipelines/runtime.yml b/eng/pipelines/runtime.yml
index aad556c6b3330..341399ad2c0ee 100644
--- a/eng/pipelines/runtime.yml
+++ b/eng/pipelines/runtime.yml
@@ -795,6 +795,7 @@ jobs:
       condition:
         or(
           eq(dependencies.evaluate_paths.outputs['SetPathVars_coreclr.containsChange'], true),
+          eq(dependencies.evaluate_paths.outputs['SetPathVars_libraries.containsChange'], true),
           eq(dependencies.evaluate_paths.outputs['SetPathVars_installer.containsChange'], true),
           eq(dependencies.evaluate_paths.outputs['SetPathVars_mono_excluding_wasm.containsChange'], true),
           eq(variables['isRollingBuild'], true))
@@ -816,6 +817,7 @@ jobs:
       condition:
         or(
           eq(dependencies.evaluate_paths.outputs['SetPathVars_coreclr.containsChange'], true),
+          eq(dependencies.evaluate_paths.outputs['SetPathVars_libraries.containsChange'], true),
           eq(dependencies.evaluate_paths.outputs['SetPathVars_installer.containsChange'], true),
           eq(dependencies.evaluate_paths.outputs['SetPathVars_mono_excluding_wasm.containsChange'], true),
           eq(variables['isRollingBuild'], true))
diff --git a/src/tests/issues.targets b/src/tests/issues.targets
index 5955fe7411ce2..10e3db7c01da7 100644
--- a/src/tests/issues.targets
+++ b/src/tests/issues.targets
@@ -2741,6 +2741,90 @@
         <ExcludeList Include = "$(XunitTestBinBase)/JIT/SIMD/VectorConvert_ro_Target_64Bit/**">
             <Issue>https://github.com/dotnet/runtime/issues/75359</Issue>
         </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Aes/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Bmi1/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Bmi1.X64/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Bmi2/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Bmi2.X64/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/General/VectorRet_r/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/General/VectorRet_ro/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/General/IsSupported_r/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/General/IsSupported_ro/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/General/VectorArray_r/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/General/VectorArray_ro/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Pclmulqdq/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse1/Shuffle_r/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse1/Shuffle_ro/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse1/Sse_r/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse1/Sse_ro/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse1.X64/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse2/Sse2_r/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse2/Sse2_ro/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse2.X64/Sse2.X64_r/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse2.X64/Sse2.X64_ro/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse3/Sse3_r/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse3/Sse3_ro/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse41/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse41.X64/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse41_Overloaded/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Sse42/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
+        <ExcludeList Include = "$(XunitTestBinBase)/JIT/HardwareIntrinsics/X86/Ssse3/**">
+            <Issue>https://github.com/dotnet/runtime/issues/75767</Issue>
+        </ExcludeList>
     </ItemGroup>
 
     <ItemGroup Condition="'$(RuntimeFlavor)' == 'mono' and '$(RuntimeVariant)' == 'llvmfullaot' ">