diff --git a/src/libraries/Common/src/Interop/FreeBSD/Interop.Libraries.cs b/src/libraries/Common/src/Interop/FreeBSD/Interop.Libraries.cs
index dc12091e1c02c..59b869c16510c 100644
--- a/src/libraries/Common/src/Interop/FreeBSD/Interop.Libraries.cs
+++ b/src/libraries/Common/src/Interop/FreeBSD/Interop.Libraries.cs
@@ -5,7 +5,6 @@ internal static partial class Interop
 {
     internal static partial class Libraries
     {
-        internal const string Odbc32 = "libodbc.so.2";
         internal const string MsQuic = "libmsquic.so";
     }
 }
diff --git a/src/libraries/Common/src/Interop/Linux/Interop.Libraries.cs b/src/libraries/Common/src/Interop/Linux/Interop.Libraries.cs
index a8b0bd05a4079..e140e238c487d 100644
--- a/src/libraries/Common/src/Interop/Linux/Interop.Libraries.cs
+++ b/src/libraries/Common/src/Interop/Linux/Interop.Libraries.cs
@@ -8,7 +8,6 @@ internal static partial class Libraries
         // Duplicated from Android for Linux Bionic
         internal const string Liblog = "liblog";
 
-        internal const string Odbc32 = "libodbc.so.2";
         internal const string OpenLdap = "libldap-2.5.so.0";
         internal const string MsQuic = "libmsquic.so";
     }
diff --git a/src/libraries/Common/src/Interop/OSX/Interop.Libraries.cs b/src/libraries/Common/src/Interop/OSX/Interop.Libraries.cs
index 36cdea9e1bd9a..9ae92de254da1 100644
--- a/src/libraries/Common/src/Interop/OSX/Interop.Libraries.cs
+++ b/src/libraries/Common/src/Interop/OSX/Interop.Libraries.cs
@@ -10,7 +10,6 @@ internal static partial class Libraries
         internal const string CFNetworkLibrary = "/System/Library/Frameworks/CFNetwork.framework/CFNetwork";
         internal const string libobjc = "/usr/lib/libobjc.dylib";
         internal const string libproc = "/usr/lib/libproc.dylib";
-        internal const string Odbc32 = "libodbc.2.dylib";
         internal const string OpenLdap = "libldap.dylib";
         internal const string SystemConfigurationLibrary = "/System/Library/Frameworks/SystemConfiguration.framework/SystemConfiguration";
         internal const string AppleCryptoNative = "libSystem.Security.Cryptography.Native.Apple";
diff --git a/src/libraries/Common/src/Interop/Unix/Interop.Odbc.cs b/src/libraries/Common/src/Interop/Unix/Interop.Odbc.cs
new file mode 100644
index 0000000000000..96e64bdda18a3
--- /dev/null
+++ b/src/libraries/Common/src/Interop/Unix/Interop.Odbc.cs
@@ -0,0 +1,38 @@
+// Licensed to the .NET Foundation under one or more agreements.
+// The .NET Foundation licenses this file to you under the MIT license.
+
+using System;
+using System.Reflection;
+using System.Runtime.InteropServices;
+
+internal static partial class Interop
+{
+    internal static partial class Libraries
+    {
+        internal const string Odbc32 = "libodbc";
+    }
+
+    internal static partial class Odbc
+    {
+        internal static string GetNativeLibraryName()
+        {
+            if (OperatingSystem.IsMacOS() || OperatingSystem.IsIOS() || OperatingSystem.IsTvOS() || OperatingSystem.IsWatchOS())
+            {
+                return "libodbc.2.dylib";
+            }
+            return "libodbc.so.2";
+        }
+
+        static Odbc()
+        {
+            NativeLibrary.SetDllImportResolver(Assembly.GetExecutingAssembly(), (libraryName, assembly, searchPath) =>
+            {
+                if (libraryName == Libraries.Odbc32)
+                {
+                    return NativeLibrary.Load(GetNativeLibraryName(), assembly, default);
+                }
+                return default;
+            });
+        }
+    }
+}
diff --git a/src/libraries/System.Data.Odbc/src/System.Data.Odbc.csproj b/src/libraries/System.Data.Odbc/src/System.Data.Odbc.csproj
index b65bc3ae54d0c..30399b2f3b692 100644
--- a/src/libraries/System.Data.Odbc/src/System.Data.Odbc.csproj
+++ b/src/libraries/System.Data.Odbc/src/System.Data.Odbc.csproj
@@ -1,7 +1,7 @@
 <Project Sdk="Microsoft.NET.Sdk">
 
   <PropertyGroup>
-    <TargetFrameworks>$(NetCoreAppCurrent)-windows;$(NetCoreAppCurrent)-freebsd;$(NetCoreAppCurrent)-illumos;$(NetCoreAppCurrent)-solaris;$(NetCoreAppCurrent)-linux;$(NetCoreAppCurrent)-osx;$(NetCoreAppCurrent)-ios;$(NetCoreAppCurrent)-tvos;$(NetCoreAppCurrent);$(NetCoreAppPrevious)-windows;$(NetCoreAppPrevious)-freebsd;$(NetCoreAppPrevious)-illumos;$(NetCoreAppPrevious)-solaris;$(NetCoreAppPrevious)-linux;$(NetCoreAppPrevious)-osx;$(NetCoreAppPrevious)-ios;$(NetCoreAppPrevious)-tvos;$(NetCoreAppPrevious);$(NetCoreAppMinimum)-windows;$(NetCoreAppMinimum)-freebsd;$(NetCoreAppMinimum)-linux;$(NetCoreAppMinimum)-osx;$(NetCoreAppMinimum);netstandard2.0;$(NetFrameworkMinimum)</TargetFrameworks>
+    <TargetFrameworks>$(NetCoreAppCurrent)-windows;$(NetCoreAppCurrent)-unix;$(NetCoreAppCurrent);$(NetCoreAppPrevious)-windows;$(NetCoreAppPrevious)-unix;$(NetCoreAppPrevious);$(NetCoreAppMinimum)-windows;$(NetCoreAppMinimum)-unix;netstandard2.0;$(NetFrameworkMinimum)</TargetFrameworks>
     <AllowUnsafeBlocks>true</AllowUnsafeBlocks>
     <NoWarn>$(NoWarn);CA2249;CA1838</NoWarn>
     <EnableAOTAnalyzer>false</EnableAOTAnalyzer>
@@ -136,14 +136,9 @@ System.Data.Odbc.OdbcTransaction</PackageDescription>
              Link="Common\System\Runtime\InteropServices\HandleRefMarshaller.cs" />
   </ItemGroup>
 
-  <ItemGroup Condition="'$(TargetPlatformIdentifier)' == 'linux' or '$(TargetPlatformIdentifier)' == 'freebsd' or '$(TargetPlatformIdentifier)' == 'illumos' or '$(TargetPlatformIdentifier)' == 'solaris'">
-    <Compile Include="$(CommonPath)Interop\Linux\Interop.Libraries.cs"
-             Link="Common\Interop\Linux\Interop.Libraries.cs" />
-  </ItemGroup>
-
-  <ItemGroup Condition="'$(TargetPlatformIdentifier)' == 'osx' or '$(TargetPlatformIdentifier)' == 'ios' or '$(TargetPlatformIdentifier)' == 'tvos'">
-    <Compile Include="$(CommonPath)Interop\OSX\Interop.Libraries.cs"
-             Link="Common\Interop\OSX\Interop.Libraries.cs" />
+  <ItemGroup Condition="'$(TargetPlatformIdentifier)' == 'unix'">
+    <Compile Include="$(CommonPath)Interop\Unix\Interop.Odbc.cs"
+             Link="Common\Interop\Unix\Interop.Odbc.cs" />
   </ItemGroup>
 
   <ItemGroup Condition="'$(TargetPlatformIdentifier)' == 'windows'">
diff --git a/src/libraries/System.Data.Odbc/tests/Helpers.cs b/src/libraries/System.Data.Odbc/tests/Helpers.cs
index ccfbf0692d386..5db421ec5ced9 100644
--- a/src/libraries/System.Data.Odbc/tests/Helpers.cs
+++ b/src/libraries/System.Data.Odbc/tests/Helpers.cs
@@ -16,7 +16,7 @@ private static bool CheckOdbcIsAvailable() =>
 #if TargetsWindows
                 !PlatformDetection.IsWindowsNanoServer && (!PlatformDetection.IsWindowsServerCore || Environment.Is64BitProcess);
 #else
-                NativeLibrary.TryLoad(Interop.Libraries.Odbc32, out _);
+                NativeLibrary.TryLoad(Interop.Odbc.GetNativeLibraryName(), out _);
 #endif
     }
 }
diff --git a/src/libraries/System.Data.Odbc/tests/System.Data.Odbc.Tests.csproj b/src/libraries/System.Data.Odbc/tests/System.Data.Odbc.Tests.csproj
index c208fe67433a9..81645a849ccbb 100644
--- a/src/libraries/System.Data.Odbc/tests/System.Data.Odbc.Tests.csproj
+++ b/src/libraries/System.Data.Odbc/tests/System.Data.Odbc.Tests.csproj
@@ -1,6 +1,6 @@
 <Project Sdk="Microsoft.NET.Sdk">
   <PropertyGroup>
-    <TargetFrameworks>$(NetCoreAppCurrent)-windows;$(NetCoreAppCurrent)-freebsd;$(NetCoreAppCurrent)-linux;$(NetCoreAppCurrent)-osx;$(NetCoreAppCurrent)-ios;$(NetCoreAppCurrent)-tvos;$(NetFrameworkMinimum)</TargetFrameworks>
+    <TargetFrameworks>$(NetCoreAppCurrent)-windows;$(NetCoreAppCurrent)-unix;$(NetFrameworkMinimum)</TargetFrameworks>
   </PropertyGroup>
   <!-- DesignTimeBuild requires all the TargetFramework Derived Properties to not be present in the first property group. -->
   <PropertyGroup>
@@ -19,21 +19,9 @@
     <Compile Include="TestCommon\CheckConnStrSetupFactAttribute.cs" />
     <Compile Include="OdbcParameterTests.cs" />
   </ItemGroup>
-  <ItemGroup Condition="'$(TargetPlatformIdentifier)' != 'windows' and '$(TargetFrameworkIdentifier)' != '.NETFramework'">
-    <Compile Include="$(CommonPath)Interop\Unix\Interop.Libraries.cs"
-             Link="Common\Interop\Unix\Interop.Libraries.cs" />
-  </ItemGroup>
-  <ItemGroup Condition="'$(TargetPlatformIdentifier)' == 'linux'">
-    <Compile Include="$(CommonPath)Interop\Linux\Interop.Libraries.cs"
-             Link="Common\Interop\Linux\Interop.Libraries.cs" />
-  </ItemGroup>
-  <ItemGroup Condition="'$(TargetPlatformIdentifier)' == 'osx' or '$(TargetPlatformIdentifier)' == 'ios' or '$(TargetPlatformIdentifier)' == 'tvos'">
-    <Compile Include="$(CommonPath)Interop\OSX\Interop.Libraries.cs"
-             Link="Common\Interop\OSX\Interop.Libraries.cs" />
-  </ItemGroup>
-  <ItemGroup Condition="'$(TargetPlatformIdentifier)' == 'freebsd'">
-    <Compile Include="$(CommonPath)Interop\FreeBSD\Interop.Libraries.cs"
-             Link="Common\Interop\FreeBSD\Interop.Libraries.cs" />
+  <ItemGroup Condition="'$(TargetPlatformIdentifier)' == 'unix'">
+    <Compile Include="$(CommonPath)Interop\Unix\Interop.Odbc.cs"
+             Link="Common\Interop\Unix\Interop.Odbc.cs" />
   </ItemGroup>
   <ItemGroup Condition="'$(TargetPlatformIdentifier)' == 'windows' or '$(TargetFrameworkIdentifier)' == '.NETFramework'">
     <Compile Include="$(CommonPath)Interop\Windows\Interop.Libraries.cs"