diff --git a/src/Persisters/Collection/OneToManyPersister.php b/src/Persisters/Collection/OneToManyPersister.php
index f39415fc0c9..6769acca909 100644
--- a/src/Persisters/Collection/OneToManyPersister.php
+++ b/src/Persisters/Collection/OneToManyPersister.php
@@ -8,6 +8,8 @@
 use Doctrine\Common\Collections\Criteria;
 use Doctrine\DBAL\Exception as DBALException;
 use Doctrine\DBAL\Types\Type;
+use Doctrine\ORM\EntityNotFoundException;
+use Doctrine\ORM\Mapping\MappingException;
 use Doctrine\ORM\PersistentCollection;
 use Doctrine\ORM\Utility\PersisterHelper;
 
@@ -166,7 +168,11 @@ public function loadCriteria(PersistentCollection $collection, Criteria $criteri
         throw new BadMethodCallException('Filtering a collection by Criteria is not supported by this CollectionPersister.');
     }
 
-    /** @throws DBALException */
+    /**
+     * @throws DBALException
+     * @throws EntityNotFoundException
+     * @throws MappingException
+     */
     private function deleteEntityCollection(PersistentCollection $collection): int
     {
         $mapping     = $collection->getMapping();
@@ -186,6 +192,13 @@ private function deleteEntityCollection(PersistentCollection $collection): int
         $statement = 'DELETE FROM ' . $this->quoteStrategy->getTableName($targetClass, $this->platform)
             . ' WHERE ' . implode(' = ? AND ', $columns) . ' = ?';
 
+        if ($targetClass->isInheritanceTypeSingleTable()) {
+            $discriminatorColumn = $targetClass->getDiscriminatorColumn();
+            $statement          .= ' AND ' . $discriminatorColumn['name'] . ' = ?';
+            $parameters[]        = $targetClass->discriminatorValue;
+            $types[]             = $discriminatorColumn['type'];
+        }
+
         $numAffected = $this->conn->executeStatement($statement, $parameters, $types);
 
         assert(is_int($numAffected));
diff --git a/tests/Tests/ORM/Functional/Ticket/GH11500Test.php b/tests/Tests/ORM/Functional/Ticket/GH11500Test.php
new file mode 100644
index 00000000000..4be3bf2b76e
--- /dev/null
+++ b/tests/Tests/ORM/Functional/Ticket/GH11500Test.php
@@ -0,0 +1,137 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Doctrine\Tests\ORM\Functional\Ticket;
+
+use Doctrine\Common\Collections\ArrayCollection;
+use Doctrine\Common\Collections\Collection;
+use Doctrine\ORM\Exception\ORMException;
+use Doctrine\ORM\Mapping as ORM;
+use Doctrine\Tests\OrmFunctionalTestCase;
+
+class GH11500Test extends OrmFunctionalTestCase
+{
+    protected function setUp(): void
+    {
+        parent::setUp();
+
+        $this->setUpEntitySchema([
+            GH11500AbstractTestEntity::class,
+            GH11500TestEntityOne::class,
+            GH11500TestEntityTwo::class,
+            GH11500TestEntityHolder::class,
+        ]);
+    }
+
+    /**
+     * @throws ORMException
+     */
+    public function testDeleteOneToManyCollectionWithSingleTableInheritance(): void
+    {
+        $testEntityOne    = new GH11500TestEntityOne();
+        $testEntityTwo    = new GH11500TestEntityTwo();
+        $testEntityHolder = new GH11500TestEntityHolder();
+
+        $testEntityOne->testEntityHolder = $testEntityHolder;
+        $testEntityHolder->testEntityOnes->add($testEntityOne);
+
+        $testEntityTwo->testEntityHolder = $testEntityHolder;
+        $testEntityHolder->testEntityTwos->add($testEntityTwo);
+
+        $em = $this->getEntityManager();
+        $em->persist($testEntityOne);
+        $em->persist($testEntityTwo);
+        $em->persist($testEntityHolder);
+        $em->flush();
+
+        $testEntityTwosBeforeRemovalOfTestEntityOnes = $testEntityHolder->testEntityTwos->toArray();
+
+        $testEntityHolder->testEntityOnes = new ArrayCollection();
+        $em->persist($testEntityHolder);
+        $em->flush();
+        $em->refresh($testEntityHolder);
+
+        static::assertEmpty($testEntityHolder->testEntityOnes->toArray(), 'All records should have been deleted');
+        static::assertEquals($testEntityTwosBeforeRemovalOfTestEntityOnes, $testEntityHolder->testEntityTwos->toArray(), 'Different Entity\'s records should not have been deleted');
+    }
+}
+
+
+
+/**
+ * @ORM\Entity
+ * @ORM\Table(name="one_to_many_single_table_inheritance_test_entities")
+ * @ORM\InheritanceType("SINGLE_TABLE")
+ * @ORM\DiscriminatorColumn(name="type", type="string")
+ * @ORM\DiscriminatorMap({"test_entity_one"="GH11500TestEntityOne", "test_entity_two"="GH11500TestEntityTwo"})
+ */
+class GH11500AbstractTestEntity
+{
+    /**
+     * @ORM\Id
+     * @ORM\Column(type="integer")
+     * @ORM\GeneratedValue
+     *
+     * @var int
+     */
+    public $id;
+}
+
+
+/** @ORM\Entity */
+class GH11500TestEntityOne extends GH11500AbstractTestEntity
+{
+    /**
+     * @ORM\ManyToOne(targetEntity="GH11500TestEntityHolder", inversedBy="testEntityOnes")
+     * @ORM\JoinColumn(name="test_entity_holder_id", referencedColumnName="id")
+     *
+     * @var GH11500TestEntityHolder
+     */
+    public $testEntityHolder;
+}
+
+/** @ORM\Entity */
+class GH11500TestEntityTwo extends GH11500AbstractTestEntity
+{
+    /**
+     * @ORM\ManyToOne(targetEntity="GH11500TestEntityHolder", inversedBy="testEntityTwos")
+     * @ORM\JoinColumn(name="test_entity_holder_id", referencedColumnName="id")
+     *
+     * @var GH11500TestEntityHolder
+     */
+    public $testEntityHolder;
+}
+
+/** @ORM\Entity */
+class GH11500TestEntityHolder
+{
+    /**
+     * @ORM\Id
+     * @ORM\Column(type="integer")
+     * @ORM\GeneratedValue
+     *
+     * @var int
+     */
+    public $id;
+
+    /**
+     * @ORM\OneToMany(targetEntity="GH11500TestEntityOne", mappedBy="testEntityHolder", orphanRemoval=true)
+     *
+     * @var Collection
+     */
+    public $testEntityOnes;
+
+    /**
+     * @ORM\OneToMany(targetEntity="GH11500TestEntityTwo", mappedBy="testEntityHolder", orphanRemoval=true)
+     *
+     * @var Collection
+     */
+    public $testEntityTwos;
+
+    public function __construct()
+    {
+        $this->testEntityOnes = new ArrayCollection();
+        $this->testEntityTwos = new ArrayCollection();
+    }
+}