diff --git a/docs/en/reference/working-with-objects.rst b/docs/en/reference/working-with-objects.rst
index d88b814e8c4..cc889ddde3f 100644
--- a/docs/en/reference/working-with-objects.rst
+++ b/docs/en/reference/working-with-objects.rst
@@ -338,10 +338,11 @@ Performance of different deletion strategies
 Deleting an object with all its associated objects can be achieved
 in multiple ways with very different performance impacts.
 
-1. If an association is marked as ``CASCADE=REMOVE`` Doctrine ORM
-   will fetch this association. If its a Single association it will
-   pass this entity to
-   ``EntityManager#remove()``. If the association is a collection, Doctrine will loop over all    its elements and pass them to``EntityManager#remove()``.
+1. If an association is marked as ``CASCADE=REMOVE`` Doctrine ORM will
+   fetch this association. If it's a Single association it will pass
+   this entity to ``EntityManager#remove()``. If the association is a
+   collection, Doctrine will loop over all its elements and pass them to
+   ``EntityManager#remove()``.
    In both cases the cascade remove semantics are applied recursively.
    For large object graphs this removal strategy can be very costly.
 2. Using a DQL ``DELETE`` statement allows you to delete multiple
diff --git a/src/NativeQuery.php b/src/NativeQuery.php
index aa44539d544..782983d50ec 100644
--- a/src/NativeQuery.php
+++ b/src/NativeQuery.php
@@ -50,7 +50,15 @@ protected function _doExecute()
         $types      = [];
 
         foreach ($this->getParameters() as $parameter) {
-            $name  = $parameter->getName();
+            $name = $parameter->getName();
+
+            if ($parameter->typeWasSpecified()) {
+                $parameters[$name] = $parameter->getValue();
+                $types[$name]      = $parameter->getType();
+
+                continue;
+            }
+
             $value = $this->processParameterValue($parameter->getValue());
             $type  = $parameter->getValue() === $value
                 ? $parameter->getType()
diff --git a/src/Persisters/Collection/OneToManyPersister.php b/src/Persisters/Collection/OneToManyPersister.php
index 6769acca909..1e032e99b49 100644
--- a/src/Persisters/Collection/OneToManyPersister.php
+++ b/src/Persisters/Collection/OneToManyPersister.php
@@ -13,10 +13,13 @@
 use Doctrine\ORM\PersistentCollection;
 use Doctrine\ORM\Utility\PersisterHelper;
 
+use function array_fill;
+use function array_keys;
 use function array_merge;
 use function array_reverse;
 use function array_values;
 use function assert;
+use function count;
 use function implode;
 use function is_int;
 use function is_string;
@@ -194,9 +197,12 @@ private function deleteEntityCollection(PersistentCollection $collection): int
 
         if ($targetClass->isInheritanceTypeSingleTable()) {
             $discriminatorColumn = $targetClass->getDiscriminatorColumn();
-            $statement          .= ' AND ' . $discriminatorColumn['name'] . ' = ?';
-            $parameters[]        = $targetClass->discriminatorValue;
-            $types[]             = $discriminatorColumn['type'];
+            $discriminatorValues = $targetClass->discriminatorValue ? [$targetClass->discriminatorValue] : array_keys($targetClass->discriminatorMap);
+            $statement          .= ' AND ' . $discriminatorColumn['name'] . ' IN (' . implode(', ', array_fill(0, count($discriminatorValues), '?')) . ')';
+            foreach ($discriminatorValues as $discriminatorValue) {
+                $parameters[] = $discriminatorValue;
+                $types[]      = $discriminatorColumn['type'];
+            }
         }
 
         $numAffected = $this->conn->executeStatement($statement, $parameters, $types);
diff --git a/src/Persisters/Entity/BasicEntityPersister.php b/src/Persisters/Entity/BasicEntityPersister.php
index 00fe7b03703..5ca00cb007e 100644
--- a/src/Persisters/Entity/BasicEntityPersister.php
+++ b/src/Persisters/Entity/BasicEntityPersister.php
@@ -832,17 +832,42 @@ public function loadOneToOneEntity(array $assoc, $sourceEntity, array $identifie
 
         $computedIdentifier = [];
 
+        /** @var array<string,mixed>|null $sourceEntityData */
+        $sourceEntityData = null;
+
         // TRICKY: since the association is specular source and target are flipped
         foreach ($owningAssoc['targetToSourceKeyColumns'] as $sourceKeyColumn => $targetKeyColumn) {
             if (! isset($sourceClass->fieldNames[$sourceKeyColumn])) {
-                throw MappingException::joinColumnMustPointToMappedField(
-                    $sourceClass->name,
-                    $sourceKeyColumn
-                );
-            }
+                // The likely case here is that the column is a join column
+                // in an association mapping. However, there is no guarantee
+                // at this point that a corresponding (generally identifying)
+                // association has been mapped in the source entity. To handle
+                // this case we directly reference the column-keyed data used
+                // to initialize the source entity before throwing an exception.
+                $resolvedSourceData = false;
+                if (! isset($sourceEntityData)) {
+                    $sourceEntityData = $this->em->getUnitOfWork()->getOriginalEntityData($sourceEntity);
+                }
+
+                if (isset($sourceEntityData[$sourceKeyColumn])) {
+                    $dataValue = $sourceEntityData[$sourceKeyColumn];
+                    if ($dataValue !== null) {
+                        $resolvedSourceData                                                    = true;
+                        $computedIdentifier[$targetClass->getFieldForColumn($targetKeyColumn)] =
+                            $dataValue;
+                    }
+                }
 
-            $computedIdentifier[$targetClass->getFieldForColumn($targetKeyColumn)] =
-                $sourceClass->reflFields[$sourceClass->fieldNames[$sourceKeyColumn]]->getValue($sourceEntity);
+                if (! $resolvedSourceData) {
+                    throw MappingException::joinColumnMustPointToMappedField(
+                        $sourceClass->name,
+                        $sourceKeyColumn
+                    );
+                }
+            } else {
+                $computedIdentifier[$targetClass->getFieldForColumn($targetKeyColumn)] =
+                    $sourceClass->reflFields[$sourceClass->fieldNames[$sourceKeyColumn]]->getValue($sourceEntity);
+            }
         }
 
         $targetEntity = $this->load($computedIdentifier, null, $assoc);
diff --git a/tests/Tests/Models/OneToOneInverseSideWithAssociativeIdLoad/InverseSide.php b/tests/Tests/Models/OneToOneInverseSideWithAssociativeIdLoad/InverseSide.php
new file mode 100644
index 00000000000..0dcb9a93a1b
--- /dev/null
+++ b/tests/Tests/Models/OneToOneInverseSideWithAssociativeIdLoad/InverseSide.php
@@ -0,0 +1,34 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Doctrine\Tests\Models\OneToOneInverseSideWithAssociativeIdLoad;
+
+use Doctrine\ORM\Mapping\Entity;
+use Doctrine\ORM\Mapping\Id;
+use Doctrine\ORM\Mapping\JoinColumn;
+use Doctrine\ORM\Mapping\OneToOne;
+use Doctrine\ORM\Mapping\Table;
+
+/**
+ * @Entity()
+ * @Table(name="one_to_one_inverse_side_assoc_id_load_inverse")
+ */
+class InverseSide
+{
+    /**
+     * Associative id (owning identifier)
+     *
+     * @var InverseSideIdTarget
+     * @Id()
+     * @OneToOne(targetEntity=InverseSideIdTarget::class, inversedBy="inverseSide")
+     * @JoinColumn(nullable=false, name="associativeId")
+     */
+    public $associativeId;
+
+    /**
+     * @var OwningSide
+     * @OneToOne(targetEntity=OwningSide::class, mappedBy="inverse")
+     */
+    public $owning;
+}
diff --git a/tests/Tests/Models/OneToOneInverseSideWithAssociativeIdLoad/InverseSideIdTarget.php b/tests/Tests/Models/OneToOneInverseSideWithAssociativeIdLoad/InverseSideIdTarget.php
new file mode 100644
index 00000000000..5746abc8c76
--- /dev/null
+++ b/tests/Tests/Models/OneToOneInverseSideWithAssociativeIdLoad/InverseSideIdTarget.php
@@ -0,0 +1,33 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Doctrine\Tests\Models\OneToOneInverseSideWithAssociativeIdLoad;
+
+use Doctrine\ORM\Mapping\Column;
+use Doctrine\ORM\Mapping\Entity;
+use Doctrine\ORM\Mapping\GeneratedValue;
+use Doctrine\ORM\Mapping\Id;
+use Doctrine\ORM\Mapping\OneToOne;
+use Doctrine\ORM\Mapping\Table;
+
+/**
+ * @Entity()
+ * @Table(name="one_to_one_inverse_side_assoc_id_load_inverse_id_target")
+ */
+class InverseSideIdTarget
+{
+    /**
+     * @var string
+     * @Id()
+     * @Column(type="string", length=255)
+     * @GeneratedValue(strategy="NONE")
+     */
+    public $id;
+
+    /**
+     * @var InverseSide
+     * @OneToOne(targetEntity=InverseSide::class, mappedBy="associativeId")
+     */
+    public $inverseSide;
+}
diff --git a/tests/Tests/Models/OneToOneInverseSideWithAssociativeIdLoad/OwningSide.php b/tests/Tests/Models/OneToOneInverseSideWithAssociativeIdLoad/OwningSide.php
new file mode 100644
index 00000000000..0b3fc7861a3
--- /dev/null
+++ b/tests/Tests/Models/OneToOneInverseSideWithAssociativeIdLoad/OwningSide.php
@@ -0,0 +1,37 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Doctrine\Tests\Models\OneToOneInverseSideWithAssociativeIdLoad;
+
+use Doctrine\ORM\Mapping\Column;
+use Doctrine\ORM\Mapping\Entity;
+use Doctrine\ORM\Mapping\GeneratedValue;
+use Doctrine\ORM\Mapping\Id;
+use Doctrine\ORM\Mapping\JoinColumn;
+use Doctrine\ORM\Mapping\OneToOne;
+use Doctrine\ORM\Mapping\Table;
+
+/**
+ * @Entity()
+ * @Table(name="one_to_one_inverse_side_assoc_id_load_owning")
+ */
+class OwningSide
+{
+    /**
+     * @var string
+     * @Id()
+     * @Column(type="string", length=255)
+     * @GeneratedValue(strategy="NONE")
+     */
+    public $id;
+
+    /**
+     * Owning side
+     *
+     * @var InverseSide
+     * @OneToOne(targetEntity=InverseSide::class, inversedBy="owning")
+     * @JoinColumn(name="inverse", referencedColumnName="associativeId")
+     */
+    public $inverse;
+}
diff --git a/tests/Tests/ORM/Functional/OneToOneInverseSideWithAssociativeIdLoadAfterDqlQueryTest.php b/tests/Tests/ORM/Functional/OneToOneInverseSideWithAssociativeIdLoadAfterDqlQueryTest.php
new file mode 100644
index 00000000000..7e2ca8a120e
--- /dev/null
+++ b/tests/Tests/ORM/Functional/OneToOneInverseSideWithAssociativeIdLoadAfterDqlQueryTest.php
@@ -0,0 +1,68 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Doctrine\Tests\ORM\Functional;
+
+use Doctrine\Tests\Models\OneToOneInverseSideWithAssociativeIdLoad\InverseSide;
+use Doctrine\Tests\Models\OneToOneInverseSideWithAssociativeIdLoad\InverseSideIdTarget;
+use Doctrine\Tests\Models\OneToOneInverseSideWithAssociativeIdLoad\OwningSide;
+use Doctrine\Tests\OrmFunctionalTestCase;
+
+use function assert;
+
+class OneToOneInverseSideWithAssociativeIdLoadAfterDqlQueryTest extends OrmFunctionalTestCase
+{
+    protected function setUp(): void
+    {
+        parent::setUp();
+
+        $this->createSchemaForModels(OwningSide::class, InverseSideIdTarget::class, InverseSide::class);
+    }
+
+    /** @group GH-11108 */
+    public function testInverseSideWithAssociativeIdOneToOneLoadedAfterDqlQuery(): void
+    {
+        $owner     = new OwningSide();
+        $inverseId = new InverseSideIdTarget();
+        $inverse   = new InverseSide();
+
+        $owner->id              = 'owner';
+        $inverseId->id          = 'inverseId';
+        $inverseId->inverseSide = $inverse;
+        $inverse->associativeId = $inverseId;
+        $owner->inverse         = $inverse;
+        $inverse->owning        = $owner;
+
+        $this->_em->persist($owner);
+        $this->_em->persist($inverseId);
+        $this->_em->persist($inverse);
+        $this->_em->flush();
+        $this->_em->clear();
+
+        $fetchedInverse = $this
+            ->_em
+            ->createQueryBuilder()
+            ->select('inverse')
+            ->from(InverseSide::class, 'inverse')
+            ->andWhere('inverse.associativeId = :associativeId')
+            ->setParameter('associativeId', 'inverseId')
+            ->getQuery()
+            ->getSingleResult();
+        assert($fetchedInverse instanceof InverseSide);
+
+        self::assertInstanceOf(InverseSide::class, $fetchedInverse);
+        self::assertInstanceOf(InverseSideIdTarget::class, $fetchedInverse->associativeId);
+        self::assertInstanceOf(OwningSide::class, $fetchedInverse->owning);
+
+        $this->assertSQLEquals(
+            'select o0_.associativeid as associativeid_0 from one_to_one_inverse_side_assoc_id_load_inverse o0_ where o0_.associativeid = ?',
+            $this->getLastLoggedQuery(1)['sql']
+        );
+
+        $this->assertSQLEquals(
+            'select t0.id as id_1, t0.inverse as inverse_2 from one_to_one_inverse_side_assoc_id_load_owning t0 where t0.inverse = ?',
+            $this->getLastLoggedQuery()['sql']
+        );
+    }
+}
diff --git a/tests/Tests/ORM/Functional/Ticket/GH11501Test.php b/tests/Tests/ORM/Functional/Ticket/GH11501Test.php
new file mode 100644
index 00000000000..715137d43af
--- /dev/null
+++ b/tests/Tests/ORM/Functional/Ticket/GH11501Test.php
@@ -0,0 +1,120 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Doctrine\Tests\ORM\Functional\Ticket;
+
+use Doctrine\Common\Collections\ArrayCollection;
+use Doctrine\Common\Collections\Collection;
+use Doctrine\ORM\Exception\ORMException;
+use Doctrine\ORM\Mapping as ORM;
+use Doctrine\Tests\OrmFunctionalTestCase;
+
+class GH11501Test extends OrmFunctionalTestCase
+{
+    protected function setUp(): void
+    {
+        parent::setUp();
+
+        $this->setUpEntitySchema([
+            GH11501AbstractTestEntity::class,
+            GH11501TestEntityOne::class,
+            GH11501TestEntityTwo::class,
+            GH11501TestEntityHolder::class,
+        ]);
+    }
+
+    /**
+     * @throws ORMException
+     */
+    public function testDeleteOneToManyCollectionWithSingleTableInheritance(): void
+    {
+        $testEntityOne    = new GH11501TestEntityOne();
+        $testEntityTwo    = new GH11501TestEntityTwo();
+        $testEntityHolder = new GH11501TestEntityHolder();
+
+        $testEntityOne->testEntityHolder = $testEntityHolder;
+        $testEntityHolder->testEntities->add($testEntityOne);
+
+        $testEntityTwo->testEntityHolder = $testEntityHolder;
+        $testEntityHolder->testEntities->add($testEntityTwo);
+
+        $em = $this->getEntityManager();
+        $em->persist($testEntityOne);
+        $em->persist($testEntityTwo);
+        $em->persist($testEntityHolder);
+        $em->flush();
+
+        $testEntityHolder->testEntities = new ArrayCollection();
+        $em->persist($testEntityHolder);
+        $em->flush();
+        $em->refresh($testEntityHolder);
+
+        static::assertEmpty($testEntityHolder->testEntities->toArray(), 'All records should have been deleted');
+    }
+}
+
+
+
+/**
+ * @ORM\Entity
+ * @ORM\Table(name="one_to_many_single_table_inheritance_test_entities_parent_join")
+ * @ORM\InheritanceType("SINGLE_TABLE")
+ * @ORM\DiscriminatorColumn(name="type", type="string")
+ * @ORM\DiscriminatorMap({"test_entity_one"="GH11501TestEntityOne", "test_entity_two"="GH11501TestEntityTwo"})
+ */
+class GH11501AbstractTestEntity
+{
+    /**
+     * @ORM\Id
+     * @ORM\Column(type="integer")
+     * @ORM\GeneratedValue
+     *
+     * @var int
+     */
+    public $id;
+
+    /**
+     * @ORM\ManyToOne(targetEntity="GH11501TestEntityHolder", inversedBy="testEntities")
+     * @ORM\JoinColumn(name="test_entity_holder_id", referencedColumnName="id")
+     *
+     * @var GH11501TestEntityHolder
+     */
+    public $testEntityHolder;
+}
+
+
+/** @ORM\Entity */
+class GH11501TestEntityOne extends GH11501AbstractTestEntity
+{
+}
+
+/** @ORM\Entity */
+class GH11501TestEntityTwo extends GH11501AbstractTestEntity
+{
+}
+
+/** @ORM\Entity */
+class GH11501TestEntityHolder
+{
+    /**
+     * @ORM\Id
+     * @ORM\Column(type="integer")
+     * @ORM\GeneratedValue
+     *
+     * @var int
+     */
+    public $id;
+
+    /**
+     * @ORM\OneToMany(targetEntity="GH11501AbstractTestEntity", mappedBy="testEntityHolder", orphanRemoval=true)
+     *
+     * @var Collection
+     */
+    public $testEntities;
+
+    public function __construct()
+    {
+        $this->testEntities = new ArrayCollection();
+    }
+}
diff --git a/tests/Tests/ORM/Query/NativeQueryTest.php b/tests/Tests/ORM/Query/NativeQueryTest.php
new file mode 100644
index 00000000000..0e68389494e
--- /dev/null
+++ b/tests/Tests/ORM/Query/NativeQueryTest.php
@@ -0,0 +1,42 @@
+<?php
+
+declare(strict_types=1);
+
+namespace Doctrine\Tests\ORM\Query;
+
+use DateTime;
+use Doctrine\DBAL\Types\Types;
+use Doctrine\ORM\Query\ResultSetMapping;
+use Doctrine\ORM\UnitOfWork;
+use Doctrine\Tests\Mocks\EntityManagerMock;
+use Doctrine\Tests\OrmTestCase;
+
+class NativeQueryTest extends OrmTestCase
+{
+    /** @var EntityManagerMock */
+    protected $entityManager;
+
+    protected function setUp(): void
+    {
+        $this->entityManager = $this->getTestEntityManager();
+    }
+
+    public function testValuesAreNotBeingResolvedForSpecifiedParameterTypes(): void
+    {
+        $unitOfWork = $this->createMock(UnitOfWork::class);
+
+        $this->entityManager->setUnitOfWork($unitOfWork);
+
+        $unitOfWork
+            ->expects(self::never())
+            ->method('getSingleIdentifierValue');
+
+        $rsm = new ResultSetMapping();
+
+        $query = $this->entityManager->createNativeQuery('SELECT d.* FROM date_time_model d WHERE d.datetime = :value', $rsm);
+
+        $query->setParameter('value', new DateTime(), Types::DATETIME_MUTABLE);
+
+        self::assertEmpty($query->getResult());
+    }
+}