diff --git a/packages/dnb-eufemia/src/components/help-button/HelpButtonInline.tsx b/packages/dnb-eufemia/src/components/help-button/HelpButtonInline.tsx
index 73f6906320d..2a616cffd3d 100644
--- a/packages/dnb-eufemia/src/components/help-button/HelpButtonInline.tsx
+++ b/packages/dnb-eufemia/src/components/help-button/HelpButtonInline.tsx
@@ -138,13 +138,23 @@ export function HelpButtonInlineContent(
     update({ isOpen: false, isUserIntent: false })
   }, [update])
 
-  const keydownHandler = useCallback(
-    (event) => {
-      switch (event.code) {
-        case 'Escape':
-          onClose()
-          buttonRef.current?.focus()
-          break
+  const onKeyDown = useCallback(
+    (event: React.KeyboardEvent<HTMLButtonElement>) => {
+      if (event.currentTarget === event.target) {
+        // Firefox returns a whitespace (" ") on event.key when pressing space,
+        // therefore using .trim() can help normalize this.
+        // While userEvent.keyboard('{Space}') might return 'Unknown' on event.code,
+        // making a direct comparison less reliable across all platforms.
+        switch (event.key.trim() || event.code) {
+          case 'Enter':
+          case 'Space':
+          case 'Escape':
+            window.requestAnimationFrame(() => {
+              onClose()
+              buttonRef.current?.focus()
+            })
+            break
+        }
       }
     },
     [buttonRef, onClose]
@@ -175,7 +185,7 @@ export function HelpButtonInlineContent(
         className="dnb-no-focus"
         tabIndex={-1}
         innerRef={innerRef}
-        onKeyDown={keydownHandler}
+        onKeyDown={onKeyDown}
         breakout={breakoutFromLayout}
         roundedCorner={!breakoutFromLayout}
         innerSpace={
diff --git a/packages/dnb-eufemia/src/components/help-button/__tests__/HelpButtonInline.test.tsx b/packages/dnb-eufemia/src/components/help-button/__tests__/HelpButtonInline.test.tsx
index e86ba84ef16..f94dcb1bb09 100644
--- a/packages/dnb-eufemia/src/components/help-button/__tests__/HelpButtonInline.test.tsx
+++ b/packages/dnb-eufemia/src/components/help-button/__tests__/HelpButtonInline.test.tsx
@@ -28,13 +28,58 @@ describe('HelpButtonInline', () => {
   it('should toggle open state when Space key gets pressed', async () => {
     render(<HelpButtonInline help={{ title: 'Help title' }} />)
 
-    const button = document.querySelector('button')
+    expect(document.body).toHaveFocus()
 
-    await userEvent.type(button, '{Space}')
-    expect(button).toHaveClass('dnb-help-button__inline--open')
+    await userEvent.tab()
+    expect(document.querySelector('button')).toHaveFocus()
 
-    await userEvent.type(button, '{Space}')
-    expect(button).not.toHaveClass('dnb-help-button__inline--open')
+    await userEvent.type(document.querySelector('button'), '{Space}')
+    await waitFor(() => {
+      expect(document.querySelector('section')).toHaveFocus()
+    })
+
+    await userEvent.keyboard('{Space}')
+    await waitFor(() => {
+      expect(document.querySelector('button')).toHaveFocus()
+    })
+  })
+
+  it('should toggle open state when Enter key gets pressed', async () => {
+    render(<HelpButtonInline help={{ title: 'Help title' }} />)
+
+    expect(document.body).toHaveFocus()
+
+    await userEvent.tab()
+    expect(document.querySelector('button')).toHaveFocus()
+
+    await userEvent.keyboard('{Enter}')
+    await waitFor(() => {
+      expect(document.querySelector('section')).toHaveFocus()
+    })
+
+    await userEvent.keyboard('{Enter}')
+    await waitFor(() => {
+      expect(document.querySelector('button')).toHaveFocus()
+    })
+  })
+
+  it('should set focus on the button when closing with Escape key', async () => {
+    render(<HelpButtonInline help={{ title: 'Help title' }} />)
+
+    expect(document.body).toHaveFocus()
+
+    await userEvent.tab()
+    expect(document.querySelector('button')).toHaveFocus()
+
+    await userEvent.keyboard('{Enter}')
+    await waitFor(() => {
+      expect(document.querySelector('section')).toHaveFocus()
+    })
+
+    await userEvent.keyboard('{Escape}')
+    await waitFor(() => {
+      expect(document.querySelector('button')).toHaveFocus()
+    })
   })
 
   it('should close when Escape key on the button gets pressed', async () => {
@@ -161,7 +206,7 @@ describe('HelpButtonInline', () => {
   })
 
   it('should set focus on the content when open', async () => {
-    render(<HelpButtonInline help={{ title: 'Dialog Title' }} />)
+    render(<HelpButtonInline help={{ title: 'Help title' }} />)
 
     expect(document.body).toHaveFocus()
 
@@ -185,27 +230,8 @@ describe('HelpButtonInline', () => {
     })
   })
 
-  it('should set focus on the button when closing with Escape key', async () => {
-    render(<HelpButtonInline help={{ title: 'Dialog Title' }} />)
-
-    expect(document.body).toHaveFocus()
-
-    await userEvent.tab()
-    expect(document.querySelector('button')).toHaveFocus()
-
-    await userEvent.keyboard('{Enter}')
-    await waitFor(() => {
-      expect(document.querySelector('section')).toHaveFocus()
-    })
-
-    await userEvent.keyboard('{Escape}')
-    expect(document.querySelector('button')).toHaveFocus()
-  })
-
   it('should not set focus on the content when open is true', async () => {
-    render(
-      <HelpButtonInline help={{ open: true, title: 'Dialog Title' }} />
-    )
+    render(<HelpButtonInline help={{ open: true, title: 'Help title' }} />)
 
     expect(document.body).toHaveFocus()