diff --git a/classes/helper.php b/classes/helper.php
index adbb414..593870c 100644
--- a/classes/helper.php
+++ b/classes/helper.php
@@ -155,9 +155,10 @@ public static function get_cohort_by_item(int $itemid, string $itemtype): ?stdCl
     public static function add_enrolment_method(stdClass $course, stdClass $cohort): void {
         global $DB;
 
-        $studentrole = $DB->get_record('role', ['shortname' => self::STUDENT_ROLE]);
+        $studentrole = self::get_student_role();
 
         $fields = [
+            'enrol' => 'cohort',
             'customint1' => $cohort->id,
             'roleid' => $studentrole->id,
             'courseid' => $course->id,
@@ -169,6 +170,41 @@ public static function add_enrolment_method(stdClass $course, stdClass $cohort):
         }
     }
 
+    /**
+     * A helper  to remove enrolment method from a given course based on item details.
+     *
+     * @param stdClass $course Given course.
+     * @param int $itemid Item ID.
+     * @param string $itemtype Item type (tag, course, category).
+     */
+    public static function remove_enrolment_method(stdClass $course, int $itemid, string $itemtype): void {
+        global $DB;
+
+        $cohort = self::get_cohort_by_item($itemid, $itemtype);
+
+        if ($cohort) {
+            $studentrole = self::get_student_role();
+
+            $fields = [
+                'enrol' => 'cohort',
+                'customint1' => $cohort->id,
+                'roleid' => $studentrole->id,
+                'courseid' => $course->id,
+            ];
+
+            $instances = $DB->get_records('enrol', $fields);
+
+            if ($instances) {
+                $enrol = enrol_get_plugin('cohort');
+
+                foreach ($instances as $instance) {
+                    // Remove enrolment method.
+                    $enrol->delete_instance($instance);
+                }
+            }
+        }
+    }
+
     /**
      * Update profile field with new item.
      *
@@ -262,4 +298,15 @@ public static function add_rule(stdClass $cohort, string $fieldshortname): void
         $rule->set('enabled', 1);
         $rule->save();
     }
+
+    /**
+     * Returns a student role.
+     *
+     * @return stdClass
+     */
+    public static function get_student_role(): stdClass {
+        global $DB;
+
+        return $DB->get_record('role', ['shortname' => helper::STUDENT_ROLE]);
+    }
 }
diff --git a/classes/observer.php b/classes/observer.php
index 094795b..570c9ba 100644
--- a/classes/observer.php
+++ b/classes/observer.php
@@ -19,6 +19,7 @@
 use core\event\course_category_created;
 use core\event\course_created;
 use core\event\tag_added;
+use core\event\tag_removed;
 
 /**
  * Event observer class.
@@ -48,6 +49,23 @@ public static function tag_added(tag_added $event): void {
         helper::set_up_item($tagid, helper::ITEM_TYPE_TAG, $tagname, $course);
     }
 
+    /**
+     * Process tag_removed event.
+     *
+     * @param tag_removed $event The event.
+     */
+    public static function tag_removed(tag_removed $event): void {
+        // Check context is course context.
+        $context = $event->get_context();
+        if ($context->contextlevel != CONTEXT_COURSE && $event->other['itemtype'] != 'course') {
+            return;
+        }
+
+        $tagid = $event->other['tagid'];
+        $course = get_course($event->other['itemid']);
+        helper::remove_enrolment_method($course, $tagid, helper::ITEM_TYPE_TAG);
+    }
+
     /**
      * Process course_created event.
      *
diff --git a/db/events.php b/db/events.php
index 8d5dd1e..b1867ec 100644
--- a/db/events.php
+++ b/db/events.php
@@ -37,4 +37,8 @@
         'eventname' => '\core\event\course_category_created',
         'callback' => '\tool_enrolprofile\observer::course_category_created',
     ],
+    [
+        'eventname' => '\core\event\tag_removed',
+        'callback' => '\tool_enrolprofile\observer::tag_removed',
+    ],
 ];
diff --git a/tests/observer_test.php b/tests/observer_test.php
index ee5e586..14f334b 100644
--- a/tests/observer_test.php
+++ b/tests/observer_test.php
@@ -174,6 +174,27 @@ public function test_tag_added(): void {
         $this->assertNotEmpty($enrol);
     }
 
+    /**
+     * Check logic when removing a tag.
+     */
+    public function test_tag_removed(): void {
+        global $DB;
+
+        $course = $this->getDataGenerator()->create_course();
+        $tagname = 'A tag';
+
+        core_tag_tag::set_item_tags('core', 'course', $course->id, context_course::instance($course->id), [$tagname]);
+
+        $cohort = $DB->get_record('cohort', ['name' => $tagname]);
+        $enrol = $DB->get_record('enrol', ['courseid' => $course->id, 'enrol' => 'cohort', 'customint1' => $cohort->id]);
+        $this->assertNotEmpty($enrol);
+
+        core_tag_tag::remove_item_tag('core', 'course', $course->id, $tagname);
+
+        $enrol = $DB->get_record('enrol', ['courseid' => $course->id, 'enrol' => 'cohort', 'customint1' => $cohort->id]);
+        $this->assertEmpty($enrol);
+    }
+
     /**
      * Check logic when creating a course.
      */