diff --git a/cvat-ui/src/components/header/settings-modal/shortcut-settings.tsx b/cvat-ui/src/components/header/settings-modal/shortcut-settings.tsx
index 33ad594787ad..0736e851844b 100644
--- a/cvat-ui/src/components/header/settings-modal/shortcut-settings.tsx
+++ b/cvat-ui/src/components/header/settings-modal/shortcut-settings.tsx
@@ -44,6 +44,7 @@ function ShortcutsSettingsComponent(props: Props): JSX.Element {
         Modal.confirm({
             title: 'Are you sure you want to restore defaults?',
             okText: 'Yes',
+            className: 'cvat-shortcuts-settings-restore-modal',
             cancelText: 'No',
             onOk: () => {
                 const currentSettings = localStorage.getItem('clientSettings');
@@ -92,7 +93,9 @@ function ShortcutsSettingsComponent(props: Props): JSX.Element {
                     <List
                         dataSource={viewFilteredItems}
                         renderItem={([id, item]) => (
-                            <List.Item>
+                            <List.Item
+                                className='cvat-shortcuts-settings-collapse-item'
+                            >
                                 <List.Item.Meta
                                     className={`${item.nonActive ? 'cvat-shortcuts-settings-item-non-active' : ''}`}
                                     title={<p className='cvat-shortcuts-settings-item-title'>{item.name}</p>}
@@ -137,7 +140,7 @@ function ShortcutsSettingsComponent(props: Props): JSX.Element {
                             onChange={onSearchChange}
                             className='cvat-shortcuts-settings-search'
                         />
-                        <Button size='large' onClick={onRestoreDefaults}>Restore Defaults</Button>
+                        <Button size='large' onClick={onRestoreDefaults} className='cvat-shortcuts-settings-restore'>Restore Defaults</Button>
                     </Flex>
                 </Col>
             </Row>
diff --git a/tests/cypress/e2e/features/shortcuts.js b/tests/cypress/e2e/features/shortcuts.js
new file mode 100644
index 000000000000..f4d67e748209
--- /dev/null
+++ b/tests/cypress/e2e/features/shortcuts.js
@@ -0,0 +1,241 @@
+// Copyright (C) 2024 CVAT.ai Corporation
+//
+// SPDX-License-Identifier: MIT
+
+/// <reference types="cypress" />
+
+context('Customizable Shortcuts', () => {
+    const taskName = 'A task with markdown';
+    const serverFiles = ['images/image_1.jpg'];
+    const createRectangleShape2Points = {
+        points: 'By 2 Points',
+        type: 'Shape',
+        labelName: 'label 1',
+        firstX: 250,
+        firstY: 350,
+        secondX: 350,
+        secondY: 450,
+    };
+    let taskID = null;
+    let jobID = null;
+
+    const task = {
+        labels: [
+            {
+                name: 'label 1',
+                attributes: [
+                    {
+                        name: 'attribute 1',
+                        mutable: true,
+                        input_type: 'checkbox',
+                        default_value: 'false',
+                        values: ['false'],
+                    },
+                ],
+                type: 'any',
+            }, {
+                name: 'label 2',
+                attributes: [],
+                type: 'any',
+            }, {
+                name: 'label 3',
+                attributes: [],
+                type: 'any',
+            },
+        ],
+        name: taskName,
+        project_id: null,
+        source_storage: { location: 'local' },
+        target_storage: { location: 'local' },
+    };
+    const storage = {
+        server_files: serverFiles,
+        image_quality: 70,
+        use_zip_chunks: true,
+        use_cache: true,
+        sorting_method: 'lexicographical',
+    };
+
+    before(() => {
+        cy.visit('auth/login');
+        cy.login();
+        cy.get('.cvat-tasks-page').should('exist').and('be.visible');
+        cy.url().should('contain', '/tasks');
+        cy.headlessCreateTask(task, storage).then((response) => {
+            taskID = response.taskID;
+            [jobID] = response.jobIDs;
+        });
+    });
+
+    function testSearchShortcuts(search) {
+        const searchShortcuts = [
+            {
+                title: 'Save the job',
+                description: 'Send all changes of annotations to the server',
+            },
+            {
+                title: 'Switch automatic bordering',
+                description: 'Switch automatic bordering for polygons and polylines during drawing/editing',
+            },
+        ];
+        const searchItemClass = search === 'description' ? '.cvat-shortcuts-settings-item-title' : '.cvat-shortcuts-settings-item-description';
+        const randomSearchItem = search === 'description' ? 'random description shortcut' : 'random title shortcut';
+        cy.get('.cvat-shortcuts-settings-search input').focus();
+        for (const searchShortcut of searchShortcuts) {
+            cy.get('.cvat-shortcuts-settings-search input').type(search === 'description' ? searchShortcut.description : searchShortcut.title);
+            cy.get(searchItemClass).should('have.length', 1);
+            cy.get(searchItemClass).contains(search === 'description' ? searchShortcut.title : searchShortcut.description);
+            cy.get('.cvat-shortcuts-settings-search input').clear();
+        }
+        cy.get('.cvat-shortcuts-settings-search input').type(randomSearchItem);
+        cy.get(searchItemClass).should('not.exist');
+        cy.get('.cvat-shortcuts-settings-search input').clear();
+        cy.get('.cvat-shortcuts-settings-search input').blur();
+    }
+
+    function checkShortcutsMounted(label) {
+        cy.get('.cvat-shortcuts-modal-window-table').should('exist').and('be.visible');
+        for (let i = 1; i < 3; i++) {
+            cy.get('.cvat-shortcuts-modal-window-table').contains(label(i));
+        }
+    }
+
+    function registerF2(shouldExist) {
+        cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select').first().click();
+        cy.realPress(['F2']);
+        cy.get('.ant-modal-content').contains('Conflicting shortcuts detected');
+        cy.get(
+            shouldExist ?
+                '.ant-modal-content .ant-modal-confirm-btns .ant-btn-primary' :
+                '.ant-modal-content .ant-modal-confirm-btns .ant-btn-default',
+        ).click();
+        cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select').first().within(() => {
+            cy.get('.ant-select-selection-overflow-item').contains('f2').should(shouldExist ? 'exist' : 'not.exist');
+        });
+        if (shouldExist) {
+            cy.closeSettings();
+            cy.realPress(['F2']);
+            cy.get('.cvat-shortcuts-modal-window').should('exist').and('be.visible');
+            cy.realPress(['F2']);
+        }
+    }
+
+    after(() => {
+        cy.logout();
+    });
+
+    describe('Searching for a shortcut', () => {
+        it('Search a shortcut by its description', () => {
+            cy.openSettings();
+            cy.contains('Shortcuts').click();
+            cy.get('.cvat-shortcuts-settings-search input').should('exist').and('be.visible');
+            testSearchShortcuts('description');
+        });
+        it('Search a shortcut by its title', () => {
+            testSearchShortcuts('title');
+        });
+    });
+
+    describe('Registration and testing of new shortcuts', () => {
+        it('Registering a combination shortcut and testing if it works or not', () => {
+            cy.get('.cvat-shortcuts-settings-collapse').should('exist').and('be.visible');
+            cy.get('.cvat-shortcuts-settings-label').first().click();
+            cy.get('.cvat-shortcuts-settings-collapse-item').should('exist').and('be.visible');
+            cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select').first().click();
+            cy.realPress(['Control', 'Space']);
+            cy.closeSettings();
+            cy.realPress(['Control', 'Space']);
+            cy.get('.cvat-shortcuts-modal-window').should('exist').and('be.visible');
+            cy.realPress(['Control', 'Space']);
+            cy.openSettings();
+            registerF2(false);
+            registerF2(true);
+        });
+    });
+
+    describe('Saving, Clearing and Restoring to Default', () => {
+        it('Saving shortcuts and checking if they persist', () => {
+            cy.openSettings();
+            cy.saveSettings();
+            cy.reload();
+            cy.openSettings();
+            cy.contains('Shortcuts').click();
+            cy.get('.cvat-shortcuts-settings-collapse').should('exist').and('be.visible');
+            cy.get('.cvat-shortcuts-settings-label').first().click();
+            cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select').first().within(() => {
+                cy.get('.ant-select-selection-overflow-item').contains('ctrl+space').should('exist');
+            });
+        });
+        it('Cleaning Shortcuts', () => {
+            cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select').first().click();
+            cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select .ant-select-selection-item-remove').first().click();
+            cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select').first().within(() => {
+                cy.get('.ant-select-selection-overflow-item').contains('f1').should('not.exist');
+            });
+            cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select .ant-select-clear').first().click();
+            cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select').first().within(() => {
+                cy.get('.ant-select-selection-overflow-item').should('not.have.text');
+            });
+        });
+        it('Restoring Defaults', () => {
+            cy.get('.cvat-shortcuts-settings-restore').click();
+            cy.get('.cvat-shortcuts-settings-restore-modal .ant-btn-primary').click();
+            cy.get(
+                '.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select .ant-select-selection-overflow-item').first().should('exist').and('be.visible');
+            cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select .ant-select-selection-overflow-item').first().contains('f1');
+            cy.saveSettings();
+        });
+        it('Modifying a shortcut via local storage and testing if its conflict is resolved', () => {
+            cy.window().then((window) => {
+                const { localStorage } = window;
+                const clientSettings = JSON.parse(localStorage.getItem('clientSettings'));
+                clientSettings.shortcuts.keyMap.SWITCH_SHORTCUTS.sequences = ['f2'];
+                localStorage.setItem('clientSettings', JSON.stringify(clientSettings));
+            });
+            cy.reload();
+            cy.openSettings();
+            cy.contains('Shortcuts').click();
+            cy.get('.cvat-shortcuts-settings-collapse').should('exist').and('be.visible');
+            cy.get('.cvat-shortcuts-settings-label').first().click();
+            cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select .ant-select-selection-overflow-item').first().contains('f2');
+            cy.get('.cvat-shortcuts-settings-collapse-item .cvat-shortcuts-settings-select .ant-select-selection-overflow-item').eq(1).should('not.have.text');
+            cy.get('.cvat-shortcuts-settings-restore').click();
+            cy.get('.cvat-shortcuts-settings-restore-modal .ant-btn-primary').click();
+        });
+    });
+
+    describe('Tag Annotation, Attribute Annotation and Labels', () => {
+        it('Tag Annotation Mode, Dynamic Titles and Description', () => {
+            cy.visit(`/tasks/${taskID}/jobs/${jobID}`);
+            cy.get('.cvat-canvas-container').should('exist').and('be.visible');
+            cy.createRectangle(createRectangleShape2Points);
+            cy.changeWorkspace('Tag annotation');
+            cy.get('.cvat-canvas-container').click();
+            cy.realPress(['F1']);
+            cy.get('.cvat-shortcuts-modal-window').should('exist').and('be.visible');
+            cy.get('.cvat-shortcuts-modal-window .ant-pagination-item-2').click();
+            checkShortcutsMounted((i) => `Create a new tag "label ${i}"`);
+            cy.realPress(['F1']);
+        });
+        it('Attribute Annotation Mode, Dynamic Titles and Description', () => {
+            cy.changeWorkspace('Attribute annotation');
+            cy.get('.cvat-canvas-container').click();
+            cy.realPress(['F1']);
+            cy.get('.cvat-shortcuts-modal-window').should('exist').and('be.visible');
+            cy.get('.cvat-shortcuts-modal-window .ant-pagination-item-3').click();
+            cy.get('.cvat-shortcuts-modal-window-table').should('exist').and('be.visible');
+            cy.get('.cvat-shortcuts-modal-window-table').contains('Assign attribute value false');
+            cy.get('.cvat-shortcuts-modal-window-table').contains('Assign attribute value true');
+            cy.realPress(['F1']);
+        });
+        it('Labels, Dynamic Titles and Description', () => {
+            cy.changeWorkspace('Standard');
+            cy.get('.cvat-canvas-container').click();
+            cy.realPress(['F1']);
+            cy.get('.cvat-shortcuts-modal-window').should('exist').and('be.visible');
+            cy.get('.cvat-shortcuts-modal-window .ant-pagination-item-5').click();
+            checkShortcutsMounted((i) => `Switch label to label ${i}`);
+            cy.realPress(['F1']);
+        });
+    });
+});