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Reproducible paper proof of concept

Purpose

To test approaches for building a completely reproducible document. This repository should act as something of a sandbox to experiment with methods and to practice using tools.

Strategy

To be successful, the document should be able to be compiled in a fresh environment by cloning this repository and running a script/makefile.

This will require reproducible:

  • data access
  • compute environment
  • code/scripts
  • document generation

Tools

As a starting point, the following tools will be used:

  • Git. To manage the contributions of multiple people we will attempt to follow this model (http://nvie.com/posts/a-successful-git-branching-model/) for branching. tldr: don't make commits on the master branch. master only gets modified via pull requests.

  • Bookdown - an R package that enables writing technical documents in markdown

  • Singularity - a container system for reproducible/portable compute environments

  • Snakemake or Nextflow for top level managment of entire pipeline from input data to final document. Both facilitate HPC execution and Sigularity integration. See NEXTFLOW.md for details on how to run a simple pipeline using different compute environments.