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USA BA.2 with Spike L452Q substitution [284 sequences] #515

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RajLABN opened this issue Apr 3, 2022 · 1 comment

RajLABN commented Apr 3, 2022

BA.2 + S:L452Q

284 sequences & 167 from New York
Earliest sequence: Feb 09 2022

99% also carry S:S704L substitution in the USA cluster

Cov-Spectrum predicts significant growth advantage over BA.2*

Link: https://cov-spectrum.org/explore/United%20States/AllSamples/Past3M/variants?pangoLineage=BA.2*&aaMutations1=S%3AL452Q&pangoLineage1=BA.2*&analysisMode=CompareToBaseline&

Nextstrain cluster

Link: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/singleSubtreeAuspice_genome_b800_8f2cc0.json?branchLabel=aa%20mutations&c=gt-S_452&label=nuc%20mutations:C11674T,T22917A,C23673T

This mutation is present also in Lambda C.37 [https://covariants.org/shared-mutations]

Observed in SARSCoV2 Waster water analysis recently by Marc Johnson
https://twitter.com/SolidEvidence/status/1510281148659814401

Author

RajLABN commented Apr 3, 2022

Similar to #499 - will close this

RajLABN closed this as completed

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