FL.1 with ORF1a:T2300I (nsp3_T1482I), ORF1a:K4348R (nsp10_K95R), S:T478R, S:P521T and M:I8V (58 seqs, 12 countries)

[NkRMnZr]

Transferred from sars-cov-2-variants/lineage-proposals#1058

Defining Mutations: FL.1 > G5917A, C7164T(ORF1a:T2300I), A13308G(ORF1a:K4348R), C14877T > C22995G(S:T478R), C23123A(S:P521T), A26544G(M:I8V)
Query: C7164T, A13308G, C22995G
Earliest seq: 2023-08-02 (EPI_ISL_18129436, Wisconsin, USA)
Latest seq: 2023-12-04 (EPI_ISL_18603893, Noord-Holland, Netherlands)
Sampled Countries: Russia (24), UK (6: WS/3; EN/3), Netherlands (5), Israel (4), USA (3), Greece (2), Switzerland (2), China (1), Denmark (1), Ireland (1), Japan (1), Kazakhstan (1)

Genomes:

EPI_ISL_18129436, EPI_ISL_18238370, EPI_ISL_18246964, EPI_ISL_18276299, EPI_ISL_18300085, EPI_ISL_18331416, EPI_ISL_18339107, EPI_ISL_18340038, EPI_ISL_18356282, EPI_ISL_18360490, EPI_ISL_18411854, EPI_ISL_18416719-18416720, EPI_ISL_18417199, EPI_ISL_18417425, EPI_ISL_18417580, EPI_ISL_18417602, EPI_ISL_18417629, EPI_ISL_18417689-18417690, EPI_ISL_18419982, EPI_ISL_18421296, EPI_ISL_18429135, EPI_ISL_18440409, EPI_ISL_18440434, EPI_ISL_18444569, EPI_ISL_18450591, EPI_ISL_18451030, EPI_ISL_18455020, EPI_ISL_18464822, EPI_ISL_18486475, EPI_ISL_18487011, EPI_ISL_18487311, EPI_ISL_18487383, EPI_ISL_18487761, EPI_ISL_18491380, EPI_ISL_18491600, EPI_ISL_18505722, EPI_ISL_18559909, EPI_ISL_18561309, EPI_ISL_18561411, EPI_ISL_18561517, EPI_ISL_18579931, EPI_ISL_18579946, EPI_ISL_18579956, EPI_ISL_18580092, EPI_ISL_18580128, EPI_ISL_18580178, EPI_ISL_18603893, EPI_ISL_18606526, EPI_ISL_18612844

UShER:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_179ef_c1c050.json?f_userOrOld=uploaded%20sample&label=id:node_3384110

Trivia:

• Already seen a couple of recombinant with XBB.2.3* (placed at the bottom of the tree) : Russia/PRI-RII-MH145732S/2023|EPI_ISL_18417689|2023-09-14 and Russia/SPE-RII-MH145868S/2023|EPI_ISL_18416719|2023-10-03
• About 3% prevalence in Russia

[NkRMnZr]

Tracking updates

12-16, 7 seqs from Russia EPI_ISL_18638633, EPI_ISL_18638635, EPI_ISL_18638700, EPI_ISL_18638708, EPI_ISL_18638727, EPI_ISL_18638730, EPI_ISL_18638844

[FedeGueli]

Designated FL.1.8 via b89aa1c