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JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(113 seqs, 15 countries ) #2297

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xz-keg opened this issue Sep 27, 2023 · 7 comments
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JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(113 seqs, 15 countries ) #2297

xz-keg opened this issue Sep 27, 2023 · 7 comments

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@xz-keg
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xz-keg commented Sep 27, 2023

This lineage grows from 14 to 53 in 10 days, but it is well expected as an even faster sub-branch of the current fastest lineage JG.3.

From sars-cov-2-variants/lineage-proposals#829

JG.3+C7932T,C25810T(Orf1a:S2556L,Orf3a:L140F)+S:T307I(C22482T)

GISAID query: C7932T,C25810T,C22482T
No. of seqs: 53(Austria 1 Canada 1 Denmark 17 UK 20 Germany 6 Greece 1 Romania 1 Sweden 1 USA 5)

First: EPI_ISL_18210634, Denmark, 2023-8-21
Latest: EPI_ISL_18315322, UK, 2023-9-19

There is also another EG.5.1+Flip+307 branch, #2310, T307I is quite convergent.

usher

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@FedeGueli
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Doubling for submission date around 7 days , even if not all the CIs show a clear growth advantage over the parental for sure it is not slow and still interesting with a RBD mutation. cc @corneliusroemer

@xz-keg
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xz-keg commented Sep 28, 2023

+1 Italy

@xz-keg xz-keg changed the title JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(53 seqs, 9 countries ) JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(54 seqs, 10 countries ) Sep 28, 2023
@xz-keg xz-keg changed the title JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(54 seqs, 10 countries ) JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(58 seqs, 10 countries ) Sep 29, 2023
@xz-keg xz-keg changed the title JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(58 seqs, 10 countries ) JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(62 seqs, 10 countries ) Sep 30, 2023
@FedeGueli
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65

@xz-keg xz-keg changed the title JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(62 seqs, 10 countries ) JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(65 seqs, 10 countries ) Oct 2, 2023
@xz-keg
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xz-keg commented Oct 5, 2023

81, Norway, Finland

@xz-keg xz-keg changed the title JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(65 seqs, 10 countries ) JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(81 seqs, 12 countries ) Oct 5, 2023
@FedeGueli
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CLear advantage over HK.3
Schermata 2023-10-06 alle 06 24 05
Still to see if clearly advantageous over JG.3, it looks like yes but lower CI is negtive.
https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?nucMutations=G22927T%2CC23673T%2CC1889T&nucMutations1=C7932T%2CC25810T%2CC22482T&analysisMode=CompareToBaseline&

@xz-keg
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xz-keg commented Oct 10, 2023

101, France,Iceland,Israel

@xz-keg xz-keg changed the title JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(81 seqs, 12 countries ) JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(101 seqs, 15 countries ) Oct 10, 2023
@xz-keg xz-keg changed the title JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(101 seqs, 15 countries ) JG.3+Orf1a:S2556L,Orf3a:L140F,S:T307I(113 seqs, 15 countries ) Oct 12, 2023
@xz-keg
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xz-keg commented Oct 15, 2023

Designated JG.3.1

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