XBB.2.3 with S:T883I in a branch with a BA.2 defining reversion at Orf1a:S135S. Japan ( 79 seqs)

[FedeGueli]

Originally discussed in sars-cov-2-variants/lineage-proposals#281

Defining mutations:
XBB.2.3 >> > C13959T > Orf1a:S135S REV (G670T), C2119T > Orf1a:D3042N (G9389A = NSP4_D279N), C25797T > G14712T, S:T883I (C24210T)

Gisaid query : C25797T ,G14712T,C2119T

Samples : 59

IDs

EPI_ISL_17780138, EPI_ISL_17780191, EPI_ISL_17803876, EPI_ISL_17819832, EPI_ISL_17820005, EPI_ISL_17820008, EPI_ISL_17820010, EPI_ISL_17820050, EPI_ISL_17881372, EPI_ISL_17881711, EPI_ISL_17881813, EPI_ISL_17882217, EPI_ISL_17882431, EPI_ISL_17882834, EPI_ISL_17883383, EPI_ISL_17883879, EPI_ISL_17884030, EPI_ISL_17884139, EPI_ISL_17941124, EPI_ISL_17952576, EPI_ISL_17958725, EPI_ISL_17958734, EPI_ISL_17959012, EPI_ISL_17959931, EPI_ISL_17961064, EPI_ISL_17973262, EPI_ISL_17978727, EPI_ISL_17999339, EPI_ISL_18000520, EPI_ISL_18000570, EPI_ISL_18006376, EPI_ISL_18006537, EPI_ISL_18006542, EPI_ISL_18006985, EPI_ISL_18010298, EPI_ISL_18010336-18010337, EPI_ISL_18010339, EPI_ISL_18010341, EPI_ISL_18010352, EPI_ISL_18039422, EPI_ISL_18040627, EPI_ISL_18040796, EPI_ISL_18044091, EPI_ISL_18047778, EPI_ISL_18050895, EPI_ISL_18050975, EPI_ISL_18051821, EPI_ISL_18055949, EPI_ISL_18056226, EPI_ISL_18056406, EPI_ISL_18056452, EPI_ISL_18058384, EPI_ISL_18058409, EPI_ISL_18065184, EPI_ISL_18065276, EPI_ISL_18065297, EPI_ISL_18065301, EPI_ISL_18066237

Tree:

[FedeGueli]

this is not far from EG on Covspectrum maybe japanese sequencing intensity pushes it up : https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?aaMutations=Orf1b%3AD54N&nucMutations1=C25797T%2CG14712T%2CC2119T&analysisMode=CompareToBaseline&

[xz-keg]

Designated XBB.2.3.21