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FL.4 with S:D1259Y and N:T334I (292 seqs, 11 countries) #2074

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xz-keg opened this issue Jun 28, 2023 · 7 comments
Closed

FL.4 with S:D1259Y and N:T334I (292 seqs, 11 countries) #2074

xz-keg opened this issue Jun 28, 2023 · 7 comments

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@xz-keg
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xz-keg commented Jun 28, 2023

from sars-cov-2-variants/lineage-proposals#140
FL.4+C2416T+C29274T(N:T334)+G25337T(S:D1259Y)
GISAID query: C2416T,C29274T,G25337T

Usher classifies it on an FL.2+orf1b:V1092F(FL.4 defining)+ A4579T(reversion of FL.2 defining) branch, which is actually FL.4

No. of seqs: 175(Canada 1 UK 1 Japan 6 Laos 1 New Zealand 1 Singapore 4(2 from China), South Korea 1 Thailand 1 USA 10 China 149)
171 on GISAID, and also C_AA023179.1, C_AA016907.1, C_AA013770.1, C_AA024637.1 on GenBase

First seq: EPI_ISL_17433565, 2023-3-13, Hong Kong
Latest: EPI_ISL_17850212, 2023-6-15, Fujian
usher
屏幕截图 2023-06-27 215615

@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (171 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (175 seqs, 10 countries) Jun 28, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (175 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (180 seqs, 10 countries) Jun 29, 2023
@Over-There-Is
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C_AA023179.1=EPI_ISL_17794707 T2416Crev
C_AA016907.1=EPI_ISL_17697604 C2416N
C_AA013770.1=EPI_ISL_17632946 searchable with query C2416T, C29274T, G25337T
C_AA024637.1 is not uploaded to gisaid

@Over-There-Is
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182 seq on GISAID with C2416T, C29274T, G25337T now, including the dropped-out sequences and genbase sequences it will be 185.

@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (180 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (185 seqs, 10 countries) Jul 4, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (185 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (193 seqs, 10 countries) Jul 8, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (193 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (194 seqs, 10 countries) Jul 9, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (194 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (195 seqs, 10 countries) Jul 12, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (195 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (200 seqs, 10 countries) Jul 14, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (200 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (207 seqs, 10 countries) Jul 15, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (207 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (208 seqs, 10 countries) Jul 18, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (208 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (219 seqs, 10 countries) Jul 20, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (219 seqs, 10 countries) FL.4 with S:D1259Y and N:T334I (219 seqs, 11 countries) Jul 20, 2023
@xz-keg
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xz-keg commented Jul 20, 2023

219, Australia.

I'm glad that the misplacement issue of this branch seems fixed in recent usher versions.

@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (219 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (225 seqs, 11 countries) Jul 22, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (225 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (227 seqs, 11 countries) Jul 25, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (227 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (270 seqs, 11 countries) Jul 28, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (270 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (272 seqs, 11 countries) Jul 30, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (272 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (277 seqs, 11 countries) Aug 3, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (277 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (278 seqs, 11 countries) Aug 6, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (278 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (279 seqs, 11 countries) Aug 8, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (279 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (280 seqs, 11 countries) Aug 9, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (280 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (282 seqs, 11 countries) Aug 12, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (282 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (284 seqs, 11 countries) Aug 14, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (284 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (285 seqs, 11 countries) Aug 18, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (285 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (286 seqs, 11 countries) Aug 23, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (286 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (288 seqs, 11 countries) Aug 26, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (288 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (291 seqs, 11 countries) Sep 3, 2023
@xz-keg xz-keg changed the title FL.4 with S:D1259Y and N:T334I (291 seqs, 11 countries) FL.4 with S:D1259Y and N:T334I (292 seqs, 11 countries) Sep 7, 2023
@xz-keg
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xz-keg commented Sep 10, 2023

Designated FL.4.11

@Over-There-Is
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It seems all FL.4.11 should have C3773T(Orf1a:R1170C), and a few sequences dropped it out.

@xz-keg
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xz-keg commented Sep 13, 2023

It seems all FL.4.11 should have C3773T(Orf1a:R1170C), and a few sequences dropped it out.

Can you confirm that all seqs not belonging to that have that pos masked?

@xz-keg xz-keg closed this as completed Sep 13, 2023
@Over-There-Is
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Guangdong/GDCDC_GZ_0124/2023|EPI_ISL_17584613|2023-04-14 and Fujian/FCDC-QZ05S067/2023|EPI_ISL_17729827|2023-05-15 share T26903C with 88 sequences with C3773T.
Yunnan/YNCDC-1483/2023|EPI_ISL_17966375|2023-06-23 and Jiangxi/JXJDZ-018/2023|EPI_ISL_17794481|2023-04-25 share A27372T with 73 sequence, then Yunnan/YNCDC-1483/2023|EPI_ISL_17966375|2023-06-23 shares A22029T with 30 sequences and C1441T with 19 sequences additionally, and Jiangxi/JXJDZ-018/2023|EPI_ISL_17794481|2023-04-25 is potential recombined or contaminated with FR.1*.
USA/NY-URMC-N3S1G116-1/2023|EPI_ISL_17695644|2023-05-06 shares C25614T with 16 sequences.
Guangdong/GDCDC_GZ_0372/2023|EPI_ISL_17698245|2023-05-09 shares T8835C and T15521A with 2 sequences, then additionally shares C25803T with 1 sequence.
I did not find sequences having same extra mutations with Hubei/HCDC-WH1229/2023|EPI_ISL_17645498|2023-05-04, but it has T11956Crev and A23854Crev. So, its T3773Crev is probably artefact too. And Guangdong/GDCDC_GZ_0267/2023|EPI_ISL_17698237|2023-04-26(G26577Crev) probably has C3773T too.

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