CH.1.1.1 sublineage with S:I714V likely emerged in Malaysia (35 sequences)

[FedeGueli]

Despite being just 21 seuqences this possible sublineage of CH.1.1.1 shows a great diversity with clusters or singlets which have further acquired S:356T or S:M177K. This is due the fact likely emerged in Malaysia where sequencing intensity is low.

tree:

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_2d1da_e78f10.json?label=id:node_8178446

Defining mutations: CH.1.1.1 + T24991A + Orf1a:A427V (C1545T) + ORF1a:K6541R (A19886G) + S:I714V (A23702G)

Gisaid query: Spike_I714V,NSP16_Q28R,Spike_K444T,Spike_L452R,Spike_N185D

Sequences: 21
EPI_ISL_16222769, EPI_ISL_16352256, EPI_ISL_16412723,
EPI_ISL_16415305, EPI_ISL_16415309, EPI_ISL_16448295,
EPI_ISL_16448304, EPI_ISL_16483022, EPI_ISL_16504717,
EPI_ISL_16504728, EPI_ISL_16534005, EPI_ISL_16647674,
EPI_ISL_16647698, EPI_ISL_16676367, EPI_ISL_16715343,
EPI_ISL_16735271, EPI_ISL_16735296, EPI_ISL_16735299,
EPI_ISL_16807711, EPI_ISL_16807741-16807742

Its growth advantage versus parental lineage CH.1.1.1 seems to hold both in a global search and in a restricted search to Singapore:
https://cov-spectrum.org/explore/World/AllSamples/Past2M/variants?nextcladePangoLineage=CH.1.1.1*&aaMutations1=S%3AI714V&nextcladePangoLineage1=CH.1.1.1*&analysisMode=CompareToBaseline&

[FedeGueli]

25 sequences as today. new samples from California and Singapore

[FedeGueli]

3 more sequences one from Malaysia (via Singapore) one from Singapore one from West Australia

[FedeGueli]

34 sequences as today last 5 uploaded by England!