diff --git a/pkg/sql/comment_on_constraint.go b/pkg/sql/comment_on_constraint.go
index ff498b3e9951..2feea4f12e21 100644
--- a/pkg/sql/comment_on_constraint.go
+++ b/pkg/sql/comment_on_constraint.go
@@ -17,7 +17,6 @@ import (
 	"github.com/cockroachdb/cockroach/pkg/security"
 	"github.com/cockroachdb/cockroach/pkg/sql/catalog"
 	"github.com/cockroachdb/cockroach/pkg/sql/catalog/descpb"
-	"github.com/cockroachdb/cockroach/pkg/sql/catalog/schemadesc"
 	"github.com/cockroachdb/cockroach/pkg/sql/pgwire/pgcode"
 	"github.com/cockroachdb/cockroach/pkg/sql/pgwire/pgerror"
 	"github.com/cockroachdb/cockroach/pkg/sql/privilege"
@@ -62,8 +61,10 @@ func (n *commentOnConstraintNode) startExec(params runParams) error {
 	if err != nil {
 		return err
 	}
-	cSchema, ok := schemadesc.GetVirtualSchemaByID(n.tableDesc.GetParentSchemaID())
-	if !ok {
+	schema, err := params.p.Descriptors().GetImmutableSchemaByID(
+		params.ctx, params.extendedEvalCtx.Txn, n.tableDesc.GetParentSchemaID(), tree.SchemaLookupFlags{},
+	)
+	if err != nil {
 		return err
 	}
 
@@ -78,16 +79,16 @@ func (n *commentOnConstraintNode) startExec(params runParams) error {
 	switch kind := constraint.Kind; kind {
 	case descpb.ConstraintTypePK:
 		constraintDesc := constraint.Index
-		n.oid = hasher.PrimaryKeyConstraintOid(n.tableDesc.GetParentID(), cSchema.GetName(), n.tableDesc.GetID(), constraintDesc)
+		n.oid = hasher.PrimaryKeyConstraintOid(n.tableDesc.GetParentID(), schema.GetName(), n.tableDesc.GetID(), constraintDesc)
 	case descpb.ConstraintTypeFK:
 		constraintDesc := constraint.FK
-		n.oid = hasher.ForeignKeyConstraintOid(n.tableDesc.GetParentID(), cSchema.GetName(), n.tableDesc.GetID(), constraintDesc)
+		n.oid = hasher.ForeignKeyConstraintOid(n.tableDesc.GetParentID(), schema.GetName(), n.tableDesc.GetID(), constraintDesc)
 	case descpb.ConstraintTypeUnique:
 		constraintDesc := constraint.Index.ID
-		n.oid = hasher.UniqueConstraintOid(n.tableDesc.GetParentID(), cSchema.GetName(), n.tableDesc.GetID(), constraintDesc)
+		n.oid = hasher.UniqueConstraintOid(n.tableDesc.GetParentID(), schema.GetName(), n.tableDesc.GetID(), constraintDesc)
 	case descpb.ConstraintTypeCheck:
 		constraintDesc := constraint.CheckConstraint
-		n.oid = hasher.CheckConstraintOid(n.tableDesc.GetParentID(), cSchema.GetName(), n.tableDesc.GetID(), constraintDesc)
+		n.oid = hasher.CheckConstraintOid(n.tableDesc.GetParentID(), schema.GetName(), n.tableDesc.GetID(), constraintDesc)
 
 	}
 	// Setting the comment to NULL is the
diff --git a/pkg/sql/comment_on_constraint_test.go b/pkg/sql/comment_on_constraint_test.go
index 9e0265db231c..4ea597c3d18e 100644
--- a/pkg/sql/comment_on_constraint_test.go
+++ b/pkg/sql/comment_on_constraint_test.go
@@ -33,7 +33,9 @@ func TestCommentOnConstraint(t *testing.T) {
 		CREATE DATABASE d;
 		SET DATABASE = d;
 		CREATE TABLE t ( a int UNIQUE, b numeric CONSTRAINT positive_price CHECK (b > 0), c int CHECK (b > c), CONSTRAINT pkey PRIMARY KEY (a,c));
-		CREATE TABLE t2 (a UUID PRIMARY KEY, b int NOT NULL REFERENCES  t (a))
+		CREATE TABLE t2 (a UUID PRIMARY KEY, b int NOT NULL REFERENCES  t (a));
+		CREATE SCHEMA s;
+		CREATE TABLE s.t ( a int UNIQUE, b numeric CONSTRAINT positive_price CHECK (b > 0), c int CHECK (b > c), CONSTRAINT pkey PRIMARY KEY (a,c));
 `); err != nil {
 		t.Fatal(err)
 	}
@@ -48,6 +50,11 @@ func TestCommentOnConstraint(t *testing.T) {
 			`SELECT obj_description(oid, 'pg_constraint') FROM pg_constraint WHERE conname='t_a_key'`,
 			gosql.NullString{String: `unique_comment`, Valid: true},
 		},
+		{
+			`COMMENT ON CONSTRAINT t_a_key ON s.t IS 'unique_comment'`,
+			`SELECT obj_description(oid, 'pg_constraint') FROM pg_constraint WHERE conname='t_a_key'`,
+			gosql.NullString{String: `unique_comment`, Valid: true},
+		},
 		{
 			`COMMENT ON CONSTRAINT positive_price ON t IS 'check_comment'`,
 			`SELECT obj_description(oid, 'pg_constraint') FROM pg_constraint WHERE conname='positive_price'`,