diff --git a/packages/components/docs/sass.md b/packages/components/docs/sass.md
index e8ddae4b7dcd..b8e6168c7802 100644
--- a/packages/components/docs/sass.md
+++ b/packages/components/docs/sass.md
@@ -3806,6 +3806,7 @@ $spacing-05: $carbon--spacing-05;
   - [search [mixin]](#search-mixin)
   - [select [mixin]](#select-mixin)
   - [tabs [mixin]](#tabs-mixin)
+  - [tooltip [mixin]](#tooltip-mixin)
   - [treeview [mixin]](#treeview-mixin)
   - [carbon-switcher [mixin]](#carbon-switcher-mixin)
 
@@ -26985,7 +26986,6 @@ Tooltip styles
   }
 
   .#{$prefix}--tooltip {
-    @include box-shadow;
     @include reset;
 
     position: absolute;
@@ -26997,7 +26997,6 @@ Tooltip styles
     padding: $carbon--spacing-05;
     color: $inverse-01;
     word-wrap: break-word;
-    background: $inverse-02;
     border-radius: rem(2px);
 
     // Windows, Firefox HCM Fix
@@ -27046,6 +27045,11 @@ Tooltip styles
       }
     }
 
+    .#{$prefix}--tooltip__content {
+      background-color: $inverse-02;
+      box-shadow: 0 0 0 $spacing-05 $inverse-02, 0 2px 6px $spacing-05 rgba(0, 0, 0, 0.2);
+    }
+
     // Tooltips need to be click focusable but not sequentially focusable so the user can click within
     // the tooltip and not have it close. Because the element is not actionable it does not need
     // to have a visible focus indicator (OK'd by IBMa)
@@ -27067,6 +27071,44 @@ Tooltip styles
       content: '';
     }
 
+    &.#{$prefix}--tooltip--top.#{$prefix}--tooltip--align-start,
+    &.#{$prefix}--tooltip--bottom.#{$prefix}--tooltip--align-start {
+      .#{$prefix}--tooltip__content {
+        transform: translate(50%, 0);
+      }
+    }
+
+    &.#{$prefix}--tooltip--top.#{$prefix}--tooltip--align-end,
+    &.#{$prefix}--tooltip--bottom.#{$prefix}--tooltip--align-end {
+      .#{$prefix}--tooltip__content {
+        transform: translate(-50%, 0);
+      }
+    }
+
+    &.#{$prefix}--tooltip--left.#{$prefix}--tooltip--align-start {
+      .#{$prefix}--tooltip__content {
+        transform: translate(0, calc(9px + 50% - #{$spacing-05}));
+      }
+    }
+
+    &.#{$prefix}--tooltip--right.#{$prefix}--tooltip--align-start {
+      .#{$prefix}--tooltip__content {
+        transform: translate(0, calc(-3px + 50% - #{$spacing-05}));
+      }
+    }
+
+    &.#{$prefix}--tooltip--left.#{$prefix}--tooltip--align-end {
+      .#{$prefix}--tooltip__content {
+        transform: translate(0, calc(9px - 50% + #{$spacing-05}));
+      }
+    }
+
+    &.#{$prefix}--tooltip--right.#{$prefix}--tooltip--align-end {
+      .#{$prefix}--tooltip__content {
+        transform: translate(0, calc(-3px - 50% + #{$spacing-05}));
+      }
+    }
+
     .#{$prefix}--tooltip__footer {
       display: flex;
       align-items: center;
@@ -27288,6 +27330,7 @@ Tooltip styles
   - [carbon--spacing-07 [variable]](#carbon--spacing-07-variable)
   - [inverse-focus-ui [variable]](#inverse-focus-ui-variable)
   - [inverse-link [variable]](#inverse-link-variable)
+  - [spacing-05 [variable]](#spacing-05-variable)
   - [spacing-03 [variable]](#spacing-03-variable)
   - [interactive-04 [variable]](#interactive-04-variable)
 
diff --git a/packages/components/src/components/tooltip/_tooltip.scss b/packages/components/src/components/tooltip/_tooltip.scss
index 98fe76ca28d3..05d40e1c7ce5 100644
--- a/packages/components/src/components/tooltip/_tooltip.scss
+++ b/packages/components/src/components/tooltip/_tooltip.scss
@@ -368,7 +368,6 @@
   }
 
   .#{$prefix}--tooltip {
-    @include box-shadow;
     @include reset;
 
     position: absolute;
@@ -380,7 +379,6 @@
     padding: $carbon--spacing-05;
     color: $inverse-01;
     word-wrap: break-word;
-    background: $inverse-02;
     border-radius: rem(2px);
 
     // Windows, Firefox HCM Fix
@@ -429,6 +427,12 @@
       }
     }
 
+    .#{$prefix}--tooltip__content {
+      background-color: $inverse-02;
+      box-shadow: 0 0 0 $spacing-05 $inverse-02,
+        0 2px 6px $spacing-05 rgba(0, 0, 0, 0.2);
+    }
+
     // Tooltips need to be click focusable but not sequentially focusable so the user can click within
     // the tooltip and not have it close. Because the element is not actionable it does not need
     // to have a visible focus indicator (OK'd by IBMa)
@@ -450,6 +454,44 @@
       content: '';
     }
 
+    &.#{$prefix}--tooltip--top.#{$prefix}--tooltip--align-start,
+    &.#{$prefix}--tooltip--bottom.#{$prefix}--tooltip--align-start {
+      .#{$prefix}--tooltip__content {
+        transform: translate(calc(50% - 6px), 0);
+      }
+    }
+
+    &.#{$prefix}--tooltip--top.#{$prefix}--tooltip--align-end,
+    &.#{$prefix}--tooltip--bottom.#{$prefix}--tooltip--align-end {
+      .#{$prefix}--tooltip__content {
+        transform: translate(calc(6px - 50%), 0);
+      }
+    }
+
+    &.#{$prefix}--tooltip--left.#{$prefix}--tooltip--align-start {
+      .#{$prefix}--tooltip__content {
+        transform: translate(0, calc(9px + 50% - #{$spacing-03}));
+      }
+    }
+
+    &.#{$prefix}--tooltip--right.#{$prefix}--tooltip--align-start {
+      .#{$prefix}--tooltip__content {
+        transform: translate(0, calc(-3px + 50% - #{$spacing-03}));
+      }
+    }
+
+    &.#{$prefix}--tooltip--left.#{$prefix}--tooltip--align-end {
+      .#{$prefix}--tooltip__content {
+        transform: translate(0, calc(9px - 50% + #{$spacing-03}));
+      }
+    }
+
+    &.#{$prefix}--tooltip--right.#{$prefix}--tooltip--align-end {
+      .#{$prefix}--tooltip__content {
+        transform: translate(0, calc(-3px - 50% + #{$spacing-03}));
+      }
+    }
+
     .#{$prefix}--tooltip__footer {
       display: flex;
       align-items: center;
diff --git a/packages/react/src/components/Tooltip/Tooltip-story.js b/packages/react/src/components/Tooltip/Tooltip-story.js
index 6aaf0fcb67c5..8d08cf53489b 100644
--- a/packages/react/src/components/Tooltip/Tooltip-story.js
+++ b/packages/react/src/components/Tooltip/Tooltip-story.js
@@ -27,8 +27,15 @@ const directions = {
   'Top (top)': 'top',
   'Right (right)': 'right',
 };
+const alignments = {
+  'Start (start)': 'start',
+  'Center (center)': 'center',
+  'End (end)': 'end',
+};
+
 const props = {
   withIcon: () => ({
+    align: select('Tooltip alignment (align)', alignments, 'center'),
     direction: select('Tooltip direction (direction)', directions, 'bottom'),
     triggerText: text('Trigger text (triggerText)', 'Tooltip label'),
     tabIndex: number('Tab index (tabIndex in <Tooltip>)', 0),
@@ -39,6 +46,7 @@ const props = {
   }),
   withoutIcon: () => ({
     showIcon: false,
+    align: select('Tooltip alignment (align)', alignments, 'center'),
     direction: select('Tooltip direction (direction)', directions, 'bottom'),
     triggerText: text('Trigger text (triggerText)', 'Tooltip label'),
     tabIndex: number('Tab index (tabIndex in <Tooltip>)', 0),
@@ -49,6 +57,7 @@ const props = {
   }),
   customIcon: () => ({
     showIcon: true,
+    align: select('Tooltip alignment (align)', alignments, 'center'),
     direction: select('Tooltip direction (direction)', directions, 'bottom'),
     triggerText: text('Trigger text (triggerText)', 'Tooltip label'),
     tabIndex: number('Tab index (tabIndex in <Tooltip>)', 0),
@@ -67,6 +76,7 @@ const props = {
   }),
   customIconOnly: () => ({
     showIcon: true,
+    align: select('Tooltip alignment (align)', alignments, 'center'),
     direction: select('Tooltip direction (direction)', directions, 'bottom'),
     iconDescription: 'Helpful Information',
     tabIndex: number('Tab index (tabIndex in <Tooltip>)', 0),
diff --git a/packages/react/src/components/Tooltip/Tooltip-test.js b/packages/react/src/components/Tooltip/Tooltip-test.js
index dc7b093d3c19..08d2fab9615b 100644
--- a/packages/react/src/components/Tooltip/Tooltip-test.js
+++ b/packages/react/src/components/Tooltip/Tooltip-test.js
@@ -87,7 +87,9 @@ describe('Tooltip', () => {
             .find('[data-floating-menu-direction]')
             .first()
             .prop('className')
-        ).toBe(`${prefix}--tooltip ${prefix}--tooltip--shown tooltip--class`);
+        ).toBe(
+          `${prefix}--tooltip ${prefix}--tooltip--shown ${prefix}--tooltip--bottom ${prefix}--tooltip--align-center tooltip--class`
+        );
       });
       it('sets the trigger class', () => {
         expect(label.prop('className')).toBe(
diff --git a/packages/react/src/components/Tooltip/Tooltip.js b/packages/react/src/components/Tooltip/Tooltip.js
index 0d4d0771f71e..579d32bd4250 100644
--- a/packages/react/src/components/Tooltip/Tooltip.js
+++ b/packages/react/src/components/Tooltip/Tooltip.js
@@ -87,6 +87,12 @@ class Tooltip extends Component {
   }
 
   static propTypes = {
+    /**
+     * Specify the alignment (to the trigger button) of the tooltip.
+     * Can be one of: start, center, or end.
+     */
+    align: PropTypes.oneOf(['start', 'center', 'end']),
+
     /**
      * Contents to put into the tooltip.
      */
@@ -207,6 +213,7 @@ class Tooltip extends Component {
   };
 
   static defaultProps = {
+    align: 'center',
     direction: DIRECTION_BOTTOM,
     focusTrap: true,
     renderIcon: Information,
@@ -405,6 +412,7 @@ class Tooltip extends Component {
       className,
       triggerClassName,
       direction,
+      align,
       focusTrap,
       triggerText,
       showIcon,
@@ -422,7 +430,11 @@ class Tooltip extends Component {
 
     const tooltipClasses = classNames(
       `${prefix}--tooltip`,
-      { [`${prefix}--tooltip--shown`]: open },
+      {
+        [`${prefix}--tooltip--shown`]: open,
+        [`${prefix}--tooltip--${direction}`]: direction,
+        [`${prefix}--tooltip--align-${align}`]: align,
+      },
       className
     );