diff --git a/packages/components/src/globals/scss/_css--reset.scss b/packages/components/src/globals/scss/_css--reset.scss
index d2e91732e7d3..a74f2ed4e2c6 100644
--- a/packages/components/src/globals/scss/_css--reset.scss
+++ b/packages/components/src/globals/scss/_css--reset.scss
@@ -190,6 +190,15 @@
       box-sizing: border-box;
     }
 
+    // Safari only fix to remove added margins on buttons (see #5155)
+    @media not all and (min-resolution: 0.001dpcm) {
+      @supports (-webkit-appearance: none) {
+        button {
+          margin: 0;
+        }
+      }
+    }
+
     @include carbon--type-reset;
     @include carbon--icons;
   }