diff --git a/src/i18n/en-US.properties b/src/i18n/en-US.properties
index 62c9236cb..1e0a3ee63 100644
--- a/src/i18n/en-US.properties
+++ b/src/i18n/en-US.properties
@@ -195,6 +195,9 @@ box3d_settings_projection_label=Camera Projection
 # Settings rotate model label
 box3d_settings_rotate_label=Rotate Model
 
+# Document Preview
+document_label=Press Alt+Arrow key combinations for caret navigation and text selection within the document's contents
+
 # Annotations
 # Placeholder text for create textarea in annotation dialog
 annotation_add_comment_placeholder=Add a comment here...
diff --git a/src/lib/viewers/doc/DocBaseViewer.js b/src/lib/viewers/doc/DocBaseViewer.js
index 1f060bd85..f8a2bf4b5 100644
--- a/src/lib/viewers/doc/DocBaseViewer.js
+++ b/src/lib/viewers/doc/DocBaseViewer.js
@@ -30,7 +30,14 @@ import {
     QUERY_PARAM_ENCODING,
     STATUS_SUCCESS,
 } from '../../constants';
-import { appendQueryParams, createAssetUrlCreator, getMidpoint, getDistance, getClosestPageToPinch } from '../../util';
+import {
+    appendQueryParams,
+    createAssetUrlCreator,
+    decodeKeydown,
+    getClosestPageToPinch,
+    getDistance,
+    getMidpoint,
+} from '../../util';
 import { checkPermission, getRepresentation } from '../../file';
 import { ICON_PRINT_CHECKMARK } from '../../icons';
 import { JS, PRELOAD_JS, CSS } from './docAssets';
@@ -106,6 +113,7 @@ class DocBaseViewer extends BaseViewer {
         this.handleAnnotationControlsEscape = this.handleAnnotationControlsEscape.bind(this);
         this.handleAnnotationCreateEvent = this.handleAnnotationCreateEvent.bind(this);
         this.handleAnnotationCreatorChangeEvent = this.handleAnnotationCreatorChangeEvent.bind(this);
+        this.handleDocElKeydown = this.handleDocElKeydown.bind(this);
         this.handlePageSubmit = this.handlePageSubmit.bind(this);
         this.onThumbnailSelectHandler = this.onThumbnailSelectHandler.bind(this);
         this.pagechangingHandler = this.pagechangingHandler.bind(this);
@@ -140,6 +148,7 @@ class DocBaseViewer extends BaseViewer {
         super.setup();
 
         this.docEl = this.createViewer(document.createElement('div'));
+        this.docEl.setAttribute('aria-label', __('document_label'));
         this.docEl.classList.add('bp-doc');
         this.docEl.tabIndex = '0';
 
@@ -1114,7 +1123,7 @@ class DocBaseViewer extends BaseViewer {
      * @return {void}
      */
     bindDOMListeners() {
-        // Detects scroll so an event can be fired
+        this.docEl.addEventListener('keydown', this.handleDocElKeydown);
         this.docEl.addEventListener('scroll', this.throttledScrollHandler);
 
         if (this.hasTouch) {
@@ -1132,6 +1141,7 @@ class DocBaseViewer extends BaseViewer {
      */
     unbindDOMListeners() {
         if (this.docEl) {
+            this.docEl.removeEventListener('keydown', this.handleDocElKeydown);
             this.docEl.removeEventListener('scroll', this.throttledScrollHandler);
 
             if (this.hasTouch) {
@@ -1275,6 +1285,22 @@ class DocBaseViewer extends BaseViewer {
         this.emit('pagefocus', pageNumber);
     }
 
+    /**
+     * Handler for 'keydown' event on the bp-doc element. These conditions cannot be managed in onKeydown, as
+     * it listens for events on the top-level document element.
+     *
+     * @private
+     * @param {KeyboardEvent} event - Keydown event
+     * @return {void}
+     */
+    handleDocElKeydown(event) {
+        const key = decodeKeydown(event);
+
+        if (event.altKey && key.includes('Arrow')) {
+            event.stopPropagation(); // Prevent collection/page navigation for caret navigation users
+        }
+    }
+
     /** @inheritDoc */
     handleFullscreenEnter() {
         this.pdfViewer.currentScaleValue = 'page-fit';
diff --git a/src/lib/viewers/doc/__tests__/DocBaseViewer-test.js b/src/lib/viewers/doc/__tests__/DocBaseViewer-test.js
index 5d2d65de1..ad7fa95cc 100644
--- a/src/lib/viewers/doc/__tests__/DocBaseViewer-test.js
+++ b/src/lib/viewers/doc/__tests__/DocBaseViewer-test.js
@@ -1788,6 +1788,7 @@ describe('src/lib/viewers/doc/DocBaseViewer', () => {
                 docBase.hasTouch = false;
                 docBase.bindDOMListeners();
 
+                expect(stubs.addEventListener).toBeCalledWith('keydown', docBase.handleDocElKeydown);
                 expect(stubs.addEventListener).toBeCalledWith('scroll', docBase.throttledScrollHandler);
                 expect(stubs.addEventListener).not.toBeCalledWith('touchstart', docBase.pinchToZoomStartHandler);
                 expect(stubs.addEventListener).not.toBeCalledWith('touchmove', docBase.pinchToZoomChangeHandler);
@@ -1812,6 +1813,8 @@ describe('src/lib/viewers/doc/DocBaseViewer', () => {
 
             test('should remove the docBase element listeners if the docBase element exists', () => {
                 docBase.unbindDOMListeners();
+
+                expect(stubs.removeEventListener).toBeCalledWith('keydown', docBase.handleDocElKeydown);
                 expect(stubs.removeEventListener).toBeCalledWith('scroll', docBase.throttledScrollHandler);
             });
 
@@ -2009,6 +2012,32 @@ describe('src/lib/viewers/doc/DocBaseViewer', () => {
             });
         });
 
+        describe.only('handleDocElKeydown()', () => {
+            test.each(['Enter', 'Escape', 'Space'])('should ignore %s key events', key => {
+                const event = { key, stopPropagation: jest.fn() };
+
+                docBase.handleDocElKeydown(event);
+
+                expect(event.stopPropagation).not.toBeCalled();
+            });
+
+            test.each(['Left', 'Right', 'Up', 'Down'])('should ignore %s key events without alt', key => {
+                const event = { altKey: false, key, stopPropagation: jest.fn() };
+
+                docBase.handleDocElKeydown(event);
+
+                expect(event.stopPropagation).not.toBeCalled();
+            });
+
+            test.each(['Left', 'Right', 'Up', 'Down'])('should stop propagation for %s key events with alt', key => {
+                const event = { altKey: true, key, stopPropagation: jest.fn() };
+
+                docBase.handleDocElKeydown(event);
+
+                expect(event.stopPropagation).toBeCalled();
+            });
+        });
+
         describe('handleFullscreenEnter()', () => {
             test('should update the scale value, and resize the page', () => {
                 docBase.pdfViewer = {
diff --git a/src/lib/viewers/doc/_docBase.scss b/src/lib/viewers/doc/_docBase.scss
index cc5ad5970..96246e0f3 100644
--- a/src/lib/viewers/doc/_docBase.scss
+++ b/src/lib/viewers/doc/_docBase.scss
@@ -298,6 +298,7 @@ $thumbnail-sidebar-width: 191px; // Extra pixel to account for sidebar border
     }
 
     .textLayer {
+        caret-color: black; // Required for caret navigation on transparent text
         top: $pdfjs-page-padding;
         bottom: auto;
         opacity: 1;