diff --git a/CHANGELOG.md b/CHANGELOG.md
index c134c64b..684009b4 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -11,6 +11,7 @@ The format is based on [Keep a Changelog](https://keepachangelog.com/en/1.0.0/).
 ### Changed
 * [#46](https://github.com/stlehmann/PyQt5-stubs/pull/46) fixes QCoreApplication and QObject signals
 * [#48](https://github.com/stlehmann/PyQt5-stubs/pull/48) fixes some signals for QClipBoard, QWindows, QQuickView and QQml{Application,}Engine
+* [#49](https://github.com/stlehmann/PyQt5-stubs/pull/49) fixes QAbstractItemView.setModel to accept None
 
 ### Removed
 
diff --git a/PyQt5-stubs/QtWidgets.pyi b/PyQt5-stubs/QtWidgets.pyi
index 4dc8c64e..327032ee 100644
--- a/PyQt5-stubs/QtWidgets.pyi
+++ b/PyQt5-stubs/QtWidgets.pyi
@@ -786,7 +786,7 @@ class QAbstractItemView(QAbstractScrollArea):
     def selectionModel(self) -> QtCore.QItemSelectionModel: ...
     def setSelectionModel(self, selectionModel: QtCore.QItemSelectionModel) -> None: ...
     def model(self) -> QtCore.QAbstractItemModel: ...
-    def setModel(self, model: QtCore.QAbstractItemModel) -> None: ...
+    def setModel(self, model: typing.Optional[QtCore.QAbstractItemModel]) -> None: ...
 
 
 class QAbstractSlider(QWidget):
@@ -1591,7 +1591,7 @@ class QColumnView(QAbstractItemView):
     def selectAll(self) -> None: ...
     def setRootIndex(self, index: QtCore.QModelIndex) -> None: ...
     def setSelectionModel(self, selectionModel: QtCore.QItemSelectionModel) -> None: ...
-    def setModel(self, model: QtCore.QAbstractItemModel) -> None: ...
+    def setModel(self, model: typing.Optional[QtCore.QAbstractItemModel]) -> None: ...
     def visualRect(self, index: QtCore.QModelIndex) -> QtCore.QRect: ...
     def sizeHint(self) -> QtCore.QSize: ...
     def scrollTo(self, index: QtCore.QModelIndex, hint: QAbstractItemView.ScrollHint = ...) -> None: ...
@@ -5421,7 +5421,7 @@ class QHeaderView(QAbstractItemView):
     def length(self) -> int: ...
     def offset(self) -> int: ...
     def orientation(self) -> QtCore.Qt.Orientation: ...
-    def setModel(self, model: QtCore.QAbstractItemModel) -> None: ...
+    def setModel(self, model: typing.Optional[QtCore.QAbstractItemModel]) -> None: ...
 
 
 class QInputDialog(QDialog):
@@ -8586,7 +8586,7 @@ class QTableView(QAbstractItemView):
     def horizontalHeader(self) -> QHeaderView: ...
     def setSelectionModel(self, selectionModel: QtCore.QItemSelectionModel) -> None: ...
     def setRootIndex(self, index: QtCore.QModelIndex) -> None: ...
-    def setModel(self, model: QtCore.QAbstractItemModel) -> None: ...
+    def setModel(self, model: typing.Optional[QtCore.QAbstractItemModel]) -> None: ...
 
 
 class QTableWidgetSelectionRange(sip.simplewrapper):
@@ -9326,7 +9326,7 @@ class QTreeView(QAbstractItemView):
     def header(self) -> QHeaderView: ...
     def setSelectionModel(self, selectionModel: QtCore.QItemSelectionModel) -> None: ...
     def setRootIndex(self, index: QtCore.QModelIndex) -> None: ...
-    def setModel(self, model: QtCore.QAbstractItemModel) -> None: ...
+    def setModel(self, model: typing.Optional[QtCore.QAbstractItemModel]) -> None: ...
 
 
 class QTreeWidgetItem(sip.wrapper):