diff --git a/recipes/stxtyper/build.sh b/recipes/stxtyper/build.sh
new file mode 100644
index 0000000000000..8a9a0bcd92388
--- /dev/null
+++ b/recipes/stxtyper/build.sh
@@ -0,0 +1,11 @@
+#!/bin/bash
+
+export INCLUDES="-I${PREFIX}/include"
+export LIBPATH="-L${PREFIX}/lib"
+export CXXFLAGS="${CXXFLAGS} -O3"
+export CPPFLAGS="${CPPFLAGS} -O3 -I${PREFIX}/include"
+export LDFLAGS="${LDFLAGS} -L${PREFIX}/lib"
+
+make CXX="${CXX}" CXXFLAGS="${CXXFLAGS}" CPPFLAGS="${CPPFLAGS}" -j"${CPU_COUNT}"
+
+make install PREFIX="${PREFIX}"
diff --git a/recipes/stxtyper/meta.yaml b/recipes/stxtyper/meta.yaml
new file mode 100644
index 0000000000000..a6d1f4e54fd40
--- /dev/null
+++ b/recipes/stxtyper/meta.yaml
@@ -0,0 +1,36 @@
+{% set name = "stxtyper" %}
+{% set version = "1.0.25" %}
+{% set sha256 = "adc734340c6a10f1bfc34ca637197e93e1515d0231bd023b33ce4c07aab9578e" %}
+
+package:
+  name: {{ name|lower }}
+  version: {{ version }}
+
+source:
+  url: https://github.com/ncbi/stxtyper/archive/refs/tags/v{{ version }}.tar.gz
+  sha256: {{ sha256 }}
+
+build:
+  number: 0
+  run_exports:
+    - {{ pin_subpackage('stxtyper', max_pin='x') }}
+
+requirements:
+  build:
+    - make
+    - {{ compiler('cxx') }}
+  host:
+    - zlib
+  run:
+    - blast
+
+test:
+  commands:
+    - "stxtyper -h"
+
+about:
+  home: https://github.com/ncbi/stxtyper
+  license: Public Domain
+  license_file: LICENSE
+  summary: 'Accurately type both known and unknown Shiga toxin operons from assembled genomic sequence.'
+  dev_url: https://github.com/ncbi/stxtyper