diff --git a/recipes/pyopenms/conda_build_config.yaml b/recipes/pyopenms/conda_build_config.yaml
deleted file mode 100644
index dd7f1933d9e4e..0000000000000
--- a/recipes/pyopenms/conda_build_config.yaml
+++ /dev/null
@@ -1,19 +0,0 @@
-python:
-  - 3.9.*
-  - 3.10.*
-  - 3.11.*
-  - 3.12.*
-python_impl:
-  - cpython
-  - cpython
-  - cpython
-  - cpython
-numpy:
-  - 1.23.*
-  - 1.23.*
-  - 1.23.*
-  - 1.26.*
-zip_keys:
-  - python
-  - python_impl
-  - numpy
diff --git a/recipes/pyopenms/meta.yaml b/recipes/pyopenms/meta.yaml
index f156ccddb0a36..59cf39da0d5d7 100644
--- a/recipes/pyopenms/meta.yaml
+++ b/recipes/pyopenms/meta.yaml
@@ -17,7 +17,7 @@ source:
 
 build:
   skip: True  # [py2k or osx]
-  number: 0
+  number: 1
   run_exports:
     - {{ pin_subpackage("pyopenms", max_pin="x.x") }}  
 
@@ -35,13 +35,13 @@ requirements:
     - xerces-c
     - boost-cpp
     - qt-main >=5.15.8
-    - python {{ python }}
+    - python >=3.9,<3.13
     - cython >=0.25.2
     - autowrap >=0.22.10
     - setuptools
     - wheel
     - pip
-    - numpy {{ numpy }}
+    - numpy >=1.23.*
     - pandas
     - matplotlib-base
     - sysroot_linux-64 =2.17 # [linux]
@@ -54,8 +54,8 @@ requirements:
     - boost-cpp
     - qt-main >=5.15.8
     - eigen >=3.3.4
-    - python {{ python }}
-    - numpy {{ numpy }}
+    - python >=3.9,<3.13
+    - numpy >=1.23.*
     - pandas
     - matplotlib-base
     - sysroot_linux-64 =2.17 # [linux]