You signed in with another tab or window. Reload to refresh your session.You signed out in another tab or window. Reload to refresh your session.You switched accounts on another tab or window. Reload to refresh your session.Dismiss alert
Is your feature request related to a problem? Please describe. cnvkit is a superior alternative to copywriter for exome cases, and presumably also to Control_FREEC for whole genome cases.
Describe the solution you'd like
Clemens has implemented cnvkit in snappy, but this code hasn't been maintained. A new implementation also offers the possibility to create a panel of normals which could benefit the processing of smaller cohorts. The new implementation could also support whole genome data.
Describe alternatives you've considered
Clemens's code could perhaps be simply updated to work again with the current snappy version. We might loose the separation of the panel of normals, and perhaps also the generalisation for whole genome datasets.
The text was updated successfully, but these errors were encountered:
Is your feature request related to a problem? Please describe.
cnvkit
is a superior alternative tocopywriter
for exome cases, and presumably also toControl_FREEC
for whole genome cases.Describe the solution you'd like
Clemens has implemented
cnvkit
insnappy
, but this code hasn't been maintained. A new implementation also offers the possibility to create a panel of normals which could benefit the processing of smaller cohorts. The new implementation could also support whole genome data.Describe alternatives you've considered
Clemens's code could perhaps be simply updated to work again with the current
snappy
version. We might loose the separation of the panel of normals, and perhaps also the generalisation for whole genome datasets.The text was updated successfully, but these errors were encountered: