README.md

ActiveCut

Active learning-based interactive tool for semi-supervised image segmentation (lesion/tumor segmentation as an example of application)

Overview of the proposed algorithm

Install & usage:

To compile the code:

1. install cmake, boost and ITK libraries on your machine

2. create a new directory for out-of-source build

$ mkdir build
$ cd build
$ ccmake ../src

3. 'c' to configue and 'g' to generate makefile.

4. make

After step 4, just type

$ ./activeCutSeg

Input arguments will be printed.

Example command to run activeCut:

$ ./activeCutSeg -d ../allchannels.nii.gz -p ../mask.nii.gz --init ../userInitializationBoundingBox.nii.gz -m 10 --priorfg ../priorfg.nii.gz --priorbg ../prior.nii.gz --eta 4 -g 6 --qscoreth 3.0

• allchannels.nii.gz is an input of 4D image
• mask.nii.gz is an input mask
• userInitializationBoundingBox.nii.gz is an input of 3D bounding box (cube)
• use --priorfg to specify an input of foreground priors, which is priorfg.nii.gz in above example
• use --priorbg to specify an input of background priors, which is prior.nii.gz in above example
• --eta, -g, --qscoreth are three parameters used in the algorithm

Recommended modules:

ActiveCut takes a 4D image as input. The various channels of images can be merged into one single 4D image by using some other tools (such as convertITKformat). It is conceptually easy for activeCutSeg to use 4D image input. The output will be 4D images, too.

Before doing any testing, please install a software (Slicer or ITK-SNAP) to visually check the candidate objects for user interaction.

Citation

If you find the code useful in your research, please consider citing:

@article{wang2016cviu,
    title={Modeling 4D pathological changes by leveraging normative models},
    author={Wang, Bo and Prastawa, Marcel and Irimia, Andrei and Saha, Avishek and Liu, Wei and Goh, SY Matthew and Vespa, Paul M and Van Horn, John D and Gerig, Guido},
    journal={Computer Vision and Image Understanding},
    volume={151},
    pages={3--13},
    year={2016}
}

@inproceedings{wang2014activecut,
  title={4D active cut: An interactive tool for pathological anatomy modeling},
  author={Wang, Bo and Liu, K Wei and Prastawa, K Marcel and Irima, Andrei and Vespa, Paul M and Van Horn, John D and Fletcher, P Thomas and Gerig, Guido},
  booktitle={2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI)},
  pages={529--532},
  year={2014},
  organization={IEEE}
}