diff --git a/.changes/next-release/feature-AmazonRoute53-2525d97.json b/.changes/next-release/feature-AmazonRoute53-2525d97.json
new file mode 100644
index 000000000000..5a068b3d434b
--- /dev/null
+++ b/.changes/next-release/feature-AmazonRoute53-2525d97.json
@@ -0,0 +1,6 @@
+{
+    "type": "feature",
+    "category": "Amazon Route 53",
+    "contributor": "",
+    "description": "Amazon Route 53 now supports the Middle East (UAE) Region (me-central-1) for latency records, geoproximity records, and private DNS for Amazon VPCs in that region."
+}
diff --git a/services/route53/src/main/resources/codegen-resources/service-2.json b/services/route53/src/main/resources/codegen-resources/service-2.json
index 49dae14c5520..6bedeeb57cdb 100644
--- a/services/route53/src/main/resources/codegen-resources/service-2.json
+++ b/services/route53/src/main/resources/codegen-resources/service-2.json
@@ -1759,6 +1759,7 @@
         "eu-west-3",
         "ap-east-1",
         "me-south-1",
+        "me-central-1",
         "ap-south-1",
         "ap-southeast-1",
         "ap-southeast-2",
@@ -6317,6 +6318,7 @@
         "us-iso-east-1",
         "us-iso-west-1",
         "us-isob-east-1",
+        "me-central-1",
         "ap-southeast-1",
         "ap-southeast-2",
         "ap-southeast-3",
@@ -6344,5 +6346,5 @@
       "min":1
     }
   },
-  "documentation":"<p>Amazon Route 53 is a highly available and scalable Domain Name System (DNS) web service.</p> <p>You can use Route 53 to:</p> <ul> <li> <p>Register domain names.</p> <p>For more information, see <a href=\"https://docs.aws.amazon.com/Route53/latest/DeveloperGuide/welcome-domain-registration.html\">How domain registration works</a>.</p> </li> <li> <p>Route internet traffic to the resources for your domain</p> <p>For more information, see <a href=\"https://docs.aws.amazon.com/Route53/latest/DeveloperGuide/welcome-dns-service.html\">How internet traffic is routed to your website or web application</a>.</p> </li> <li> <p>Check the health of your resources.</p> <p>For more information, see <a href=\"https://docs.aws.amazon.com/Route53/latest/DeveloperGuide/welcome-health-checks.html\">How Route 53 checks the health of your resources</a>.</p> </li> </ul>"
+  "documentation":"<p>Amazon Route 53 is a highly available and scalable Domain Name System (DNS) web service.</p>"
 }