diff --git a/src/deadline/keyshot_submitter/Submit to AWS Deadline Cloud.py b/src/deadline/keyshot_submitter/Submit to AWS Deadline Cloud.py
index 0b0368a..1743e4b 100644
--- a/src/deadline/keyshot_submitter/Submit to AWS Deadline Cloud.py	
+++ b/src/deadline/keyshot_submitter/Submit to AWS Deadline Cloud.py	
@@ -357,7 +357,19 @@ def gui_submit(bundle_directory: str) -> Optional[dict[str, Any]]:
         return None
 
 
-def main():
+def main(lux):
+    if lux.isSceneChanged():
+        result = lux.getInputDialog(
+            title="Unsaved changes",
+            values=[(lux.DIALOG_LABEL, "You have unsaved changes. Do you want to save your file?")],
+        )
+        # result is {} if the user clicks Ok and None if the user clicks cancel
+        if result is None:
+            # Raise an exception so Keyshot shows the script's result status as "Failure" instead of "Success"
+            raise Exception("Changes must be saved before submitting.")
+        else:
+            lux.saveFile()
+
     scene_file = lux.getSceneInfo()["file"]
     external_files = lux.getExternalFiles()
     current_frame = lux.getAnimationFrame()
@@ -413,4 +425,4 @@ def main():
 
 
 if __name__ == "__main__":
-    main()
+    main(lux)
diff --git a/test/keyshot_submitter/test_keyshot_submitter.py b/test/keyshot_submitter/test_keyshot_submitter.py
index 9328f94..1c1cc41 100644
--- a/test/keyshot_submitter/test_keyshot_submitter.py
+++ b/test/keyshot_submitter/test_keyshot_submitter.py
@@ -1,9 +1,11 @@
 # Copyright Amazon.com, Inc. or its affiliates. All Rights Reserved.
+from unittest.mock import Mock
 import mock_lux  # type: ignore[import-not-found] # noqa: F401
 
 import json
 import os
 import tempfile
+import pytest
 
 
 deadline = __import__("deadline.keyshot_submitter.Submit to AWS Deadline Cloud")
@@ -242,3 +244,22 @@ def test_settings_apply_submitter_settings():
     assert sorted(settings.input_directories) == ["test_directory_2"]
     assert sorted(settings.output_directories) == ["test_directory_2", "test_directory_4"]
     assert sorted(settings.referenced_paths) == ["test_ref_path_2"]
+
+
+def test_unsaved_changes_prompt():
+    local_mock_lux = Mock()
+    local_mock_lux.isSceneChanged.return_value = True
+
+    local_mock_lux.getInputDialog.return_value = None  # emulate clicking Cancel
+    with pytest.raises(Exception):
+        submitter.main(local_mock_lux)
+    local_mock_lux.saveFile.assert_not_called()
+
+    local_mock_lux.getInputDialog.return_value = {}  # emulate clicking Ok
+    # Raise an exception so the main() handler exits after the file save operation is called.
+    # We want to verify that the saveFile call is made, but don't want to run the rest of the
+    # submitter.
+    local_mock_lux.saveFile.side_effect = Exception()
+    with pytest.raises(Exception):
+        submitter.main(local_mock_lux)
+    local_mock_lux.saveFile.assert_called()