diff --git a/LICENSE b/LICENSE new file mode 100644 index 0000000..64cc41e --- /dev/null +++ b/LICENSE @@ -0,0 +1,21 @@ +MIT License + +Copyright (c) 2022 Atlas of Variant Effects + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in all +copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE +SOFTWARE. \ No newline at end of file diff --git a/Pipfile b/Pipfile new file mode 100644 index 0000000..7ee859e --- /dev/null +++ b/Pipfile @@ -0,0 +1,23 @@ +[[source]] +name = "pypi" +url = "https://pypi.org/simple" +verify_ssl = true + +[dev-packages] + +[packages] +jupyter = "*" +jupyterlab = "*" +bs4 = "*" +requests = "*" +biopython = '*' +"biocommons.seqrepo" = "*" +gene-normalizer = ">=0.1.23" +uta-tools = ">=0.1.0" +pandas = "*" +nest_asyncio = "*" +asyncio = "*" +plotly = '*' + +[requires] +python_version = "3.8" \ No newline at end of file diff --git a/notebooks/analysis/Pipfile b/notebooks/analysis/Pipfile new file mode 100644 index 0000000..8dc2d9d --- /dev/null +++ b/notebooks/analysis/Pipfile @@ -0,0 +1,27 @@ +[[source]] +name = "pypi" +url = "https://pypi.org/simple" +verify_ssl = true + +[dev-packages] +ipykernel = "*" +jupyter = "*" + +[packages] +jupyter = "*" +jupyterlab = "*" +bs4 = "*" +requests = "*" +gene-normalizer = "==0.1.27" +biopython = '*' +pysam = "==0.18.0" +"biocommons.seqrepo" = "*" +"ga4gh.vrsatile.pydantic" = "*" +cool-seq-tool = ">=0.1.0" +pandas = "*" +nest_asyncio = "*" +asyncio = "*" +plotly = '*' + +[requires] +python_version = "3.10" diff --git a/notebooks/analysis/generate_example_mappings.ipynb b/notebooks/analysis/generate_example_mappings.ipynb new file mode 100644 index 0000000..090a736 --- /dev/null +++ b/notebooks/analysis/generate_example_mappings.ipynb @@ -0,0 +1,10278 @@ +{ + "cells": [ + { + "cell_type": "code", + "execution_count": 2, + "id": "85f18129", + "metadata": {}, + "outputs": [], + "source": [ + "import pandas as pd\n", + "import pickle\n", + "import operator\n", + "import requests\n", + "import Bio\n", + "from Bio.SeqUtils import seq1\n", + "from Bio.Seq import Seq\n", + "import math\n", + "from math import isnan\n", + "import io\n", + "import re\n", + "from ga4gh.core import sha512t24u\n", + "from ga4gh.vrs.dataproxy import SeqRepoDataProxy\n", + "from ga4gh.vrsatile.pydantic.vrs_models import Variation, Sequence, Allele, SimpleInterval, Location\n", + "from ga4gh.vrsatile.pydantic.vrsatile_models import VariationDescriptor, Expression\n", + "from ga4gh.vrs.extras.translator import Translator\n", + "from ga4gh.vrs.normalize import normalize\n", + "from biocommons.seqrepo import SeqRepo\n", + "import nest_asyncio\n", + "import asyncio\n", + "sr = SeqRepo(\"/usr/local/share/seqrepo/latest\")\n", + "from cool_seq_tool.cool_seq_tool import CoolSeqTool\n", + "from cool_seq_tool.data_sources.uta_database import UTADatabase\n", + "from cool_seq_tool.data_sources.mane_transcript_mappings import MANETranscriptMappings\n", + "from os import environ\n", + "environ[\"UTA_DB_URL\"] = 'postgresql://uta_admin:uta@localhost:5432/uta/uta_20210129'\n", + "from gene.query import QueryHandler\n", + "import hgvs.parser\n", + "import hgvs.location\n", + "import hgvs.posedit\n", + "import hgvs.edit\n", + "import hgvs.sequencevariant\n", + "import hgvs.dataproviders.uta" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "id": "fc55ffd4", + "metadata": {}, + "outputs": [], + "source": [ + "with open('results/mave_blat.pickle', 'rb') as fn:\n", + " mave_blat = pickle.load(fn)" + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "id": "44c7ba22", + "metadata": {}, + "outputs": [], + "source": [ + "# Load metadata\n", + "mave_dat = pd.read_csv('results/mave_dat.csv')" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "id": "49d3fa86", + "metadata": {}, + "outputs": [], + "source": [ + "# Load mappings data\n", + "with open('results/mappings.pickle', 'rb') as fn:\n", + " mappings_dict = pickle.load(fn)" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "id": "01156f12", + "metadata": {}, + "outputs": [], + "source": [ + "with open('results/scores_coding.pickle', 'rb') as fn:\n", + " scores_coding = pickle.load(fn)\n", + " \n", + "with open('results/scores_noncoding.pickle', 'rb') as fn:\n", + " scores_noncoding = pickle.load(fn)" + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "id": "81b5a493", + "metadata": {}, + "outputs": [], + "source": [ + "with open('results/vrs_mappings_coding_normalize_false.pickle', 'rb') as fn:\n", + " vrs_mappings_coding = pickle.load(fn)\n", + " \n", + "with open('results/vrs_mappings_noncoding_normalize_false.pickle', 'rb') as fn:\n", + " vrs_mappings_noncoding = pickle.load(fn)" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "id": "a2285339", + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "{'urn:mavedb:00000041-a-1': {'chrom': '20',\n", + " 'strand': 1,\n", + " 'target': 'Src catalytic domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P12931',\n", + " 'coverage': '750 / 750, 100.0',\n", + " 'identity': 99.86666666666666,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:52] [37397802:37397854]\n", + " 1 [52:232] [37400114:37400294]\n", + " 2 [232:309] [37401601:37401678]\n", + " 3 [309:463] [37402434:37402588]\n", + " 4 [463:595] [37402748:37402880]\n", + " 5 [595:750] [37403170:37403325]},\n", + " 'urn:mavedb:00000048-a-1': {'chrom': '2',\n", + " 'strand': -1,\n", + " 'target': 'CXCR4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P61073',\n", + " 'coverage': '1041 / 1053, 98.86039886039886',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [12:1053] [136114871:136115912]},\n", + " 'urn:mavedb:00000068-b-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'TP53 (P72R)',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '1180 / 1182, 99.83079526226734',\n", + " 'identity': 99.91525423728814,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1100:1180] [7669610:7669690]\n", + " 1 [993:1100] [7670608:7670715]\n", + " 2 [919:993] [7673534:7673608]\n", + " 3 [782:919] [7673700:7673837]\n", + " 4 [672:782] [7674180:7674290]\n", + " 5 [559:672] [7674858:7674971]\n", + " 6 [375:559] [7675052:7675236]\n", + " 7 [96:375] [7675993:7676272]\n", + " 8 [74:96] [7676381:7676403]\n", + " 9 [0:74] [7676520:7676594]},\n", + " 'urn:mavedb:00000045-c-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000018-a-1': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'HBB promoter',\n", + " 'target_type': 'Regulatory',\n", + " 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'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000083-b-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - SRSF1 (ASF/SF2) binding site',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '41 / 51, 80.3921568627451',\n", + " 'identity': 97.5609756097561,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [10:51] [32416489:32416530]},\n", + " 'urn:mavedb:00000094-a-5': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 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100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:158] [48037746:48037904]\n", + " 1 [158:355] [48040919:48041116]\n", + " 2 [355:495] [48045659:48045799]},\n", + " 'urn:mavedb:00000104-a-2': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'PARP1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '3958 / 3958, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [3107:3958] [226360690:226361541]\n", + " 1 [2992:3107] [226361968:226362083]\n", + " 2 [2930:2992] [226363098:226363160]\n", + " 3 [2802:2930] [226363942:226364070]\n", + " 4 [2649:2802] [226365001:226365154]\n", + " 5 [2550:2649] [226365953:226366052]\n", + " 6 [2421:2550] [226367479:226367608]\n", + " 7 [2298:2421] [226368198:226368321]\n", + " 8 [2214:2298] [226370433:226370517]\n", + " 9 [2085:2214] [226374225:226374354]\n", + " 10 [1889:2085] [226377107:226377303]\n", + " 11 [1756:1889] [226379141:226379274]\n", + " 12 [1687:1756] 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+ " 0 [0:12] [38551475:38551511]},\n", + " 'urn:mavedb:00000108-a-2': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'HMBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P08397',\n", + " 'coverage': '1086 / 1086, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:33] [119085033:119085066]\n", + " 1 [33:87] [119088254:119088308]\n", + " 2 [87:160] [119088634:119088707]\n", + " 3 [160:210] [119089081:119089131]\n", + " 4 [210:266] [119089216:119089272]\n", + " 5 [266:344] [119089682:119089760]\n", + " 6 [344:422] [119089989:119090067]\n", + " 7 [422:498] [119090189:119090265]\n", + " 8 [498:612] [119091412:119091526]\n", + " 9 [612:651] [119092124:119092163]\n", + " 10 [651:771] [119092403:119092523]\n", + " 11 [771:825] [119092757:119092811]\n", + " 12 [825:912] [119092934:119093021]\n", + " 13 [912:1086] [119093109:119093283]},\n", + " 'urn:mavedb:00000001-a-4': {'chrom': '16',\n", + " 'strand': 1,\n", + " 'target': 'UBE2I',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63279',\n", + " 'coverage': '477 / 477, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:66] [1314030:1314096]\n", + " 1 [66:150] [1314292:1314376]\n", + " 2 [150:223] [1315653:1315726]\n", + " 3 [223:333] [1320173:1320283]\n", + " 4 [333:413] [1320437:1320517]\n", + " 5 [413:477] [1324729:1324793]},\n", + " 'urn:mavedb:00000094-a-6': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000078-a-1': {'chrom': '16',\n", + " 'strand': 0,\n", + " 'target': 'VKOR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '163 / 163, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:57] [31094558:31094729]\n", + " 1 [57:94] [31093312:31093423]\n", + " 2 [94:163] [31091136:31091343]},\n", + " 'urn:mavedb:00000103-c-1': {'chrom': '22',\n", + " 'strand': 0,\n", + " 'target': 'MAPK1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '360 / 360, 100.0',\n", + " 'identity': 99.9071494893222,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:39] [21867323:21867440]\n", + " 1 [40:101] [21807662:21807845]\n", + " 2 [101:164] [21805849:21806038]\n", + " 3 [164:203] [21799011:21799128]\n", + " 4 [203:241] [21788694:21788808]\n", + " 5 [241:285] [21788257:21788389]\n", + " 6 [285:322] [21772872:21772983]\n", + " 7 [322:360] [21769206:21769320]},\n", + " 'urn:mavedb:00000043-a-1': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'MPL',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P40238',\n", + " 'coverage': '93 / 93, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:10] [43348992:43349002]\n", + " 1 [10:93] [43349262:43349345]},\n", + " 'urn:mavedb:00000061-d-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000046-a-1': {'chrom': '3',\n", + " 'strand': 1,\n", + " 'target': 'CD86',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42081',\n", + " 'coverage': '81 / 81, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:81] [122109290:122109371]},\n", + " 'urn:mavedb:00000081-a-1': {'chrom': '17',\n", + " 'strand': 0,\n", + " 'target': 'BRCA1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P38398',\n", + " 'coverage': '1863 / 1863, 100.0',\n", + " 'identity': 99.94623655913979,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:26] [43124018:43124096]\n", + " 1 [27:45] [43115724:43115778]\n", + " 2 [45:70] [43106457:43106532]\n", + " 3 [70:100] [43104868:43104958]\n", + " 4 [101:147] [43104121:43104259]\n", + " 5 [147:181] [43099778:43099880]\n", + " 6 [181:197] [43097245:43097293]\n", + " 7 [197:223] [43095846:43095924]\n", + " 8 [223:1365] [43091435:43094861]\n", + " 9 [1365:1395] [43090943:43091033]\n", + " 10 [1395:1451] [43082407:43082575]\n", + " 11 [1451:1494] [43076489:43076618]\n", + " 12 [1494:1558] [43074331:43074523]\n", + " 13 [1558:1662] [43070927:43071239]\n", + " 14 [1662:1691] [43067608:43067695]\n", + " 15 [1691:1717] [43063874:43063952]\n", + " 16 [1718:1731] [43063332:43063371]\n", + " 17 [1731:1759] [43057051:43057135]\n", + " 18 [1759:1777] [43051063:43051117]\n", + " 19 [1777:1802] [43049120:43049195]\n", + " 20 [1802:1822] [43047643:43047703]\n", + " 21 [1822:1863] [43045680:43045803]},\n", + " 'urn:mavedb:00000097-r-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 19',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '104 / 104, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [43057041:43057145]},\n", + " 'urn:mavedb:00000067-a-1': {'chrom': '19',\n", + " 'strand': 1,\n", + " 'target': 'TECR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9NZ01',\n", + " 'coverage': '916 / 927, 98.8133764832794',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [11:66] [14562520:14562575]\n", + " 1 [66:118] [14563205:14563257]\n", + " 2 [118:163] [14563657:14563702]\n", + " 3 [163:267] [14563799:14563903]\n", + " 4 [267:383] [14563981:14564097]\n", + " 5 [383:489] [14564181:14564287]\n", + " 6 [489:562] [14564785:14564858]\n", + " 7 [562:606] [14564948:14564992]\n", + " 8 [606:664] [14565065:14565123]\n", + " 9 [664:753] [14565201:14565290]\n", + " 10 [753:799] [14565617:14565663]\n", + " 11 [799:927] [14565743:14565871]},\n", + " 'urn:mavedb:00000001-c-2': {'chrom': '14',\n", + " 'strand': 1,\n", + " 'target': 'CALM1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P0DP23',\n", + " 'coverage': '448 / 450, 99.55555555555556',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [2:34] [90400063:90400095]\n", + " 1 [34:178] [90401258:90401402]\n", + " 2 [178:285] [90403861:90403968]\n", + " 3 [285:421] [90404378:90404514]\n", + " 4 [421:450] [90404688:90404717]},\n", + " 'urn:mavedb:00000049-a-7': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000060-a-2': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'TARDBP',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q13148',\n", + " 'coverage': '1242 / 1242, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:238] [11013727:11013965]\n", + " 1 [238:402] [11016843:11017007]\n", + " 2 [402:543] [11018732:11018873]\n", + " 3 [543:714] [11020428:11020599]\n", + " 4 [714:1242] [11022123:11022651]},\n", + " 'urn:mavedb:00000058-a-1': {'chrom': '21',\n", + " 'strand': -1,\n", + " 'target': 'Aβ42',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P05067',\n", + " 'coverage': '126 / 126, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [51:126] [25891793:25891868]\n", + " 1 [0:51] [25897572:25897623]},\n", + " 'urn:mavedb:00000045-k-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000094-a-14': {'chrom': '11',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '676 / 676, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:129] [2445098:2445485]\n", + " 1 [129:159] [2527928:2528018]\n", + " 2 [159:201] [2570627:2570753]\n", + " 3 [201:227] [2571323:2571401]\n", + " 4 [227:260] [2572010:2572109]\n", + " 5 [260:307] [2572845:2572986]\n", + " 6 [307:344] [2583434:2583545]\n", + " 7 [344:375] [2585211:2585304]\n", + " 8 [375:417] [2587566:2587692]\n", + " 9 [417:462] [2588712:2588847]\n", + " 10 [462:505] [2661953:2662082]\n", + " 11 [505:529] [2768844:2768916]\n", + " 12 [529:561] [2775956:2776052]\n", + " 13 [561:577] [2776983:2777031]\n", + " 14 [577:598] [2777974:2778037]\n", + " 15 [598:676] [2847766:2848000]},\n", + " 'urn:mavedb:00000069-a-2': {'chrom': 'X',\n", + " 'strand': 0,\n", + " 'target': 'ACE2',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9BYF1',\n", + " 'coverage': '805 / 805, 100.0',\n", + " 'identity': 99.87531172069825,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:62] [15600725:15600911]\n", + " 1 [62:115] [15594844:15595003]\n", + " 2 [115:146] [15592229:15592322]\n", + " 3 [146:194] [15591713:15591857]\n", + " 4 [195:232] [15589343:15589454]\n", + " 5 [232:267] [15587753:15587858]\n", + " 6 [267:299] [15585477:15585573]\n", + " 7 [299:356] [15581222:15581393]\n", + " 8 [356:432] [15578089:15578317]\n", + " 9 [432:481] [15575664:15575811]\n", + " 10 [481:513] [15573368:15573464]\n", + " 11 [513:554] [15572202:15572325]\n", + " 12 [555:612] [15571624:15571795]\n", + " 13 [613:632] [15570294:15570351]\n", + " 14 [632:666] [15567724:15567826]\n", + " 15 [666:704] [15566254:15566368]\n", + " 16 [704:770] [15564022:15564220]\n", + " 17 [770:805] [15561907:15562012]},\n", + " 'urn:mavedb:00000106-b-1': {'chrom': '12',\n", + " 'strand': 0,\n", + " 'target': 'AID',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '196 / 198, 98.98989898989899',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [2:52] [8606864:8607014]\n", + " 1 [52:142] [8605215:8605485]\n", + " 2 [142:181] [8604806:8604923]\n", + " 3 [181:198] [8604286:8604337]},\n", + " 'urn:mavedb:00000046-a-2': {'chrom': '3',\n", + " 'strand': 1,\n", + " 'target': 'CD86',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42081',\n", + " 'coverage': '81 / 81, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:81] [122109290:122109371]},\n", + " 'urn:mavedb:00000069-a-1': {'chrom': 'X',\n", + " 'strand': 0,\n", + " 'target': 'ACE2',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '805 / 805, 100.0',\n", + " 'identity': 99.87531172069825,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:62] [15600725:15600911]\n", + " 1 [62:115] [15594844:15595003]\n", + " 2 [115:146] [15592229:15592322]\n", + " 3 [146:194] [15591713:15591857]\n", + " 4 [195:232] [15589343:15589454]\n", + " 5 [232:267] [15587753:15587858]\n", + " 6 [267:299] [15585477:15585573]\n", + " 7 [299:356] [15581222:15581393]\n", + " 8 [356:432] [15578089:15578317]\n", + " 9 [432:481] [15575664:15575811]\n", + " 10 [481:513] [15573368:15573464]\n", + " 11 [513:554] [15572202:15572325]\n", + " 12 [555:612] [15571624:15571795]\n", + " 13 [613:632] [15570294:15570351]\n", + " 14 [632:666] [15567724:15567826]\n", + " 15 [666:704] [15566254:15566368]\n", + " 16 [704:770] [15564022:15564220]\n", + " 17 [770:805] [15561907:15562012]},\n", + " 'urn:mavedb:00000034-b-1': {'chrom': '7',\n", + " 'strand': 1,\n", + " 'target': 'ZRS enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '485 / 486, 99.79423868312757',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:485] [156791118:156791603]},\n", + " 'urn:mavedb:00000049-a-8': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000047-c-1': {'chrom': '3',\n", + " 'strand': 1,\n", + " 'target': 'CCR5',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P51681',\n", + " 'coverage': '1053 / 1053, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:1053] [46372905:46373958]},\n", + " 'urn:mavedb:00000094-a-8': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000041-b-1': {'chrom': '20',\n", + " 'strand': 1,\n", + " 'target': 'Src SH4 domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P12931',\n", + " 'coverage': '54 / 54, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:54] [37384156:37384210]},\n", + " 'urn:mavedb:00000097-o-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 18',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '101 / 101, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:101] [43063302:43063403]},\n", + " 'urn:mavedb:00000045-a-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000097-0-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Locus',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '78414 / 78414, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:78414] [43045704:43124118]},\n", + " 'urn:mavedb:00000097-h-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 5',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '109 / 109, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:109] [43104857:43104966]},\n", + " 'urn:mavedb:00000061-h-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000066-a-1': {'chrom': 'X',\n", + " 'strand': 1,\n", + " 'target': 'GDI1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P31150',\n", + " 'coverage': '1344 / 1344, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:45] [154437254:154437299]\n", + " 1 [45:153] [154438522:154438630]\n", + " 2 [153:253] [154438764:154438864]\n", + " 3 [253:388] [154439005:154439140]\n", + " 4 [388:587] [154439940:154440139]\n", + " 5 [587:719] [154440374:154440506]\n", + " 6 [719:819] [154441095:154441195]\n", + " 7 [819:991] [154441622:154441794]\n", + " 8 [991:1136] [154442110:154442255]\n", + " 9 [1136:1191] [154442373:154442428]\n", + " 10 [1191:1344] [154442519:154442672]},\n", + " 'urn:mavedb:00000021-a-1': {'chrom': '6',\n", + " 'strand': 1,\n", + " 'target': 'IRF4 enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '451 / 451, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:451] [396142:396593]},\n", + " 'urn:mavedb:00000108-a-3': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'HMBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P08397',\n", + " 'coverage': '1086 / 1086, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:33] [119085033:119085066]\n", + " 1 [33:87] [119088254:119088308]\n", + " 2 [87:160] [119088634:119088707]\n", + " 3 [160:210] [119089081:119089131]\n", + " 4 [210:266] [119089216:119089272]\n", + " 5 [266:344] [119089682:119089760]\n", + " 6 [344:422] [119089989:119090067]\n", + " 7 [422:498] [119090189:119090265]\n", + " 8 [498:612] [119091412:119091526]\n", + " 9 [612:651] [119092124:119092163]\n", + " 10 [651:771] [119092403:119092523]\n", + " 11 [771:825] [119092757:119092811]\n", + " 12 [825:912] [119092934:119093021]\n", + " 13 [912:1086] [119093109:119093283]},\n", + " 'urn:mavedb:00000094-a-15': {'chrom': '11',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '676 / 676, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:129] [2445098:2445485]\n", + " 1 [129:159] [2527928:2528018]\n", + " 2 [159:201] [2570627:2570753]\n", + " 3 [201:227] [2571323:2571401]\n", + " 4 [227:260] [2572010:2572109]\n", + " 5 [260:307] [2572845:2572986]\n", + " 6 [307:344] [2583434:2583545]\n", + " 7 [344:375] [2585211:2585304]\n", + " 8 [375:417] [2587566:2587692]\n", + " 9 [417:462] [2588712:2588847]\n", + " 10 [462:505] [2661953:2662082]\n", + " 11 [505:529] [2768844:2768916]\n", + " 12 [529:561] [2775956:2776052]\n", + " 13 [561:577] [2776983:2777031]\n", + " 14 [577:598] [2777974:2778037]\n", + " 15 [598:676] [2847766:2848000]},\n", + " 'urn:mavedb:00000031-a-1': {'chrom': '5',\n", + " 'strand': 1,\n", + " 'target': 'TERT promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '259 / 259, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:259] [1294988:1295247]},\n", + " 'urn:mavedb:00000094-a-2': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000094-a-4': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000059-a-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'p53',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04637',\n", + " 'coverage': '573 / 573, 100.0',\n", + " 'identity': 99.82547993019197,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [479:573] [7673743:7673837]\n", + " 1 [369:479] [7674180:7674290]\n", + " 2 [256:369] [7674858:7674971]\n", + " 3 [72:256] [7675052:7675236]\n", + " 4 [0:72] [7675993:7676065]},\n", + " 'urn:mavedb:00000094-a-1': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000083-i-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - AC-rich enhancer',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '41 / 51, 80.3921568627451',\n", + " 'identity': 97.5609756097561,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [10:51] [32416489:32416530]},\n", + " 'urn:mavedb:00000045-g-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000097-i-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 15',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '106 / 106, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:106] [43070917:43071023]},\n", + " 'urn:mavedb:00000097-w-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 22',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43047617:43047717]},\n", + " 'urn:mavedb:00000045-j-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000103-b-1': {'chrom': '22',\n", + " 'strand': 0,\n", + " 'target': 'MAPK1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '360 / 360, 100.0',\n", + " 'identity': 99.9071494893222,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:39] [21867323:21867440]\n", + " 1 [40:101] [21807662:21807845]\n", + " 2 [101:164] [21805849:21806038]\n", + " 3 [164:203] [21799011:21799128]\n", + " 4 [203:241] [21788694:21788808]\n", + " 5 [241:285] [21788257:21788389]\n", + " 6 [285:322] [21772872:21772983]\n", + " 7 [322:360] [21769206:21769320]},\n", + " 'urn:mavedb:00000097-g-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 5',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '109 / 109, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:109] [43104857:43104966]},\n", + " 'urn:mavedb:00000026-a-1': {'chrom': '8',\n", + " 'strand': 1,\n", + " 'target': 'MYC enhancer (rs11986220)',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '463 / 463, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:463] [127519269:127519732]},\n", + " 'urn:mavedb:00000083-j-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - pyrimidine sequence',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '42 / 51, 82.3529411764706',\n", + " 'identity': 97.61904761904762,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [9:51] [32416489:32416531]},\n", + " 'urn:mavedb:00000049-a-4': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000083-e-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - hnRNP D binding site',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '42 / 51, 82.3529411764706',\n", + " 'identity': 97.61904761904762,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [9:51] [32416489:32416531]},\n", + " 'urn:mavedb:00000014-a-1': {'chrom': '2',\n", + " 'strand': 1,\n", + " 'target': 'BCL11A enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '600 / 600, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:600] [60494939:60495539]},\n", + " 'urn:mavedb:00000097-b-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 2',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '106 / 106, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:106] [43124012:43124118]},\n", + " 'urn:mavedb:00000097-k-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 16',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '108 / 108, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:108] [43067597:43067705]},\n", + " 'urn:mavedb:00000102-0-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'PTEN',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P60484',\n", + " 'coverage': '1212 / 1212, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:79] [87864469:87864548]\n", + " 1 [79:164] [87894024:87894109]\n", + " 2 [164:209] [87925512:87925557]\n", + " 3 [209:253] [87931045:87931089]\n", + " 4 [253:492] [87933012:87933251]\n", + " 5 [492:634] [87952117:87952259]\n", + " 6 [634:801] [87957852:87958019]\n", + " 7 [801:1026] [87960893:87961118]\n", + " 8 [1026:1212] [87965286:87965472]},\n", + " 'urn:mavedb:00000001-b-2': {'chrom': '2',\n", + " 'strand': -1,\n", + " 'target': 'SUMO1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63165',\n", + " 'coverage': '297 / 306, 97.05882352941177',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [237:306] [202207252:202207321]\n", + " 1 [165:237] [202210734:202210806]\n", + " 2 [87:165] [202214356:202214434]\n", + " 3 [9:87] [202220031:202220109]},\n", + " 'urn:mavedb:00000094-a-3': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000061-g-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000001-d-1': {'chrom': '7',\n", + " 'strand': -1,\n", + " 'target': 'TPK1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9H3S4',\n", + " 'coverage': '585 / 585, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [466:585] [144453544:144453663]\n", + " 1 [354:466] [144548490:144548602]\n", + " 2 [258:354] [144623165:144623261]\n", + " 3 [185:258] [144648806:144648879]\n", + " 4 [115:185] [144682908:144682978]\n", + " 5 [43:115] [144765879:144765951]\n", + " 6 [0:43] [144835559:144835602]},\n", + " 'urn:mavedb:00000097-p-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 18',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '101 / 101, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:101] [43063302:43063403]},\n", + " 'urn:mavedb:00000097-x-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 22',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43047617:43047717]},\n", + " 'urn:mavedb:00000055-a-1': {'chrom': '13',\n", + " 'strand': 1,\n", + " 'target': 'NUDT15',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9NV35',\n", + " 'coverage': '495 / 495, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:158] [48037746:48037904]\n", + " 1 [158:355] [48040919:48041116]\n", + " 2 [355:495] [48045659:48045799]},\n", + " 'urn:mavedb:00000094-a-10': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000045-i-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000032-a-1': {'chrom': '2',\n", + " 'strand': 1,\n", + " 'target': 'UC88 enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '590 / 591, 99.83079526226734',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:590] [161238407:161238997]},\n", + " 'urn:mavedb:00000101-a-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'PTEN',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P60484',\n", + " 'coverage': '1212 / 1212, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:79] [87864469:87864548]\n", + " 1 [79:164] [87894024:87894109]\n", + " 2 [164:209] [87925512:87925557]\n", + " 3 [209:253] [87931045:87931089]\n", + " 4 [253:492] [87933012:87933251]\n", + " 5 [492:634] [87952117:87952259]\n", + " 6 [634:801] [87957852:87958019]\n", + " 7 [801:1026] [87960893:87961118]\n", + " 8 [1026:1212] [87965286:87965472]},\n", + " 'urn:mavedb:00000053-a-1': {'chrom': '17',\n", + " 'strand': 1,\n", + " 'target': 'PSD95 PDZ3',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P78352',\n", + " 'coverage': '249 / 249, 100.0',\n", + " 'identity': 74.6987951807229,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:156] [7196753:7196909]\n", + " 1 [156:249] [7196479:7196572]},\n", + " 'urn:mavedb:00000097-v-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 21',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '105 / 105, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:105] [43049102:43049207]},\n", + " 'urn:mavedb:00000091-a-1': {'chrom': '7',\n", + " 'strand': 0,\n", + " 'target': 'BRAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P15056',\n", + " 'coverage': '118 / 119, 99.15966386554622',\n", + " 'identity': 98.86039886039886,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1:29] [140777992:140778076]\n", + " 1 [29:88] [140776913:140777090]\n", + " 2 [89:105] [140754184:140754232]\n", + " 3 [105:119] [140753349:140753391]},\n", + " 'urn:mavedb:00000048-c-1': {'chrom': '2',\n", + " 'strand': -1,\n", + " 'target': 'CXCR4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P61073',\n", + " 'coverage': '1041 / 1053, 98.86039886039886',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [12:1053] [136114871:136115912]},\n", + " 'urn:mavedb:00000031-c-1': {'chrom': '5',\n", + " 'strand': 1,\n", + " 'target': 'TERT promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '259 / 259, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:259] [1294988:1295247]},\n", + " 'urn:mavedb:00000051-b-1': {'chrom': '17',\n", + " 'strand': 1,\n", + " 'target': 'ErbB2',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04626',\n", + " 'coverage': '71 / 72, 98.61111111111111',\n", + " 'identity': 95.77464788732394,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:71] [39723322:39723393]},\n", + " 'urn:mavedb:00000097-m-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 17',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '98 / 98, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:98] [43063863:43063961]},\n", + " 'urn:mavedb:00000001-b-1': {'chrom': '2',\n", + " 'strand': -1,\n", + " 'target': 'SUMO1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63165',\n", + " 'coverage': '297 / 306, 97.05882352941177',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [237:306] [202207252:202207321]\n", + " 1 [165:237] [202210734:202210806]\n", + " 2 [87:165] [202214356:202214434]\n", + " 3 [9:87] [202220031:202220109]},\n", + " 'urn:mavedb:00000103-a-1': {'chrom': '22',\n", + " 'strand': 0,\n", + " 'target': 'MAPK1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '360 / 360, 100.0',\n", + " 'identity': 99.9071494893222,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:39] [21867323:21867440]\n", + " 1 [40:101] [21807662:21807845]\n", + " 2 [101:164] [21805849:21806038]\n", + " 3 [164:203] [21799011:21799128]\n", + " 4 [203:241] [21788694:21788808]\n", + " 5 [241:285] [21788257:21788389]\n", + " 6 [285:322] [21772872:21772983]\n", + " 7 [322:360] [21769206:21769320]},\n", + " 'urn:mavedb:00000097-f-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43106445:43106545]},\n", + " 'urn:mavedb:00000057-b-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Ras',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P01112',\n", + " 'coverage': '495 / 495, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [447:495] [532707:532755]\n", + " 1 [287:447] [533452:533612]\n", + " 2 [108:287] [533765:533944]\n", + " 3 [0:108] [534211:534319]},\n", + " 'urn:mavedb:00000083-a-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - Wilms’ tumor gene',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '51 / 51, 100.0',\n", + " 'identity': 98.0392156862745,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:51] [32416489:32416540]},\n", + " 'urn:mavedb:00000097-s-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 20',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43051039:43051139]},\n", + " 'urn:mavedb:00000024-a-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'MSMB promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '591 / 591, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:591] [46046243:46046834]},\n", + " 'urn:mavedb:00000045-f-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000072-a-1': {'chrom': '14',\n", + " 'strand': 0,\n", + " 'target': 'IGHG1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P01857',\n", + " 'coverage': '106 / 106, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:106] [105741478:105741796]},\n", + " 'urn:mavedb:00000095-b-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'CYP2C9',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P11712',\n", + " 'coverage': '1470 / 1470, 100.0',\n", + " 'identity': 99.1991991991992,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:168] [94938682:94938850]\n", + " 1 [168:331] [94941857:94942020]\n", + " 2 [331:481] [94942191:94942341]\n", + " 3 [481:536] [94947778:94947833]\n", + " 4 [937:959] [94972221:94972243]\n", + " 5 [1029:1149] [94981250:94981370]\n", + " 6 [1149:1291] [94986032:94986174]\n", + " 7 [1291:1470] [94988846:94989025]},\n", + " 'urn:mavedb:00000001-a-1': {'chrom': '16',\n", + " 'strand': 1,\n", + " 'target': 'UBE2I',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63279',\n", + " 'coverage': '477 / 477, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:66] [1314030:1314096]\n", + " 1 [66:150] [1314292:1314376]\n", + " 2 [150:223] [1315653:1315726]\n", + " 3 [223:333] [1320173:1320283]\n", + " 4 [333:413] [1320437:1320517]\n", + " 5 [413:477] [1324729:1324793]},\n", + " 'urn:mavedb:00000023-a-1': {'chrom': '19',\n", + " 'strand': 1,\n", + " 'target': 'LDLR promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '318 / 318, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:318] [11089230:11089548]},\n", + " 'urn:mavedb:00000049-a-2': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000062-b-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'CYP2C19',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P33261',\n", + " 'coverage': '1443 / 1443, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:144] [94762729:94762873]\n", + " 1 [144:307] [94775057:94775220]\n", + " 2 [307:457] [94775389:94775539]\n", + " 3 [457:618] [94780498:94780659]\n", + " 4 [618:795] [94781820:94781997]\n", + " 5 [795:937] [94820495:94820637]\n", + " 6 [937:1125] [94842836:94843024]\n", + " 7 [1125:1267] [94849916:94850058]\n", + " 8 [1267:1443] [94852732:94852908]},\n", + " 'urn:mavedb:00000094-a-12': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000057-c-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Ras',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P01112',\n", + " 'coverage': '495 / 495, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [447:495] [532707:532755]\n", + " 1 [287:447] [533452:533612]\n", + " 2 [108:287] [533765:533944]\n", + " 3 [0:108] [534211:534319]},\n", + " 'urn:mavedb:00000094-a-7': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000061-f-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000001-a-2': {'chrom': '16',\n", + " 'strand': 1,\n", + " 'target': 'UBE2I',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63279',\n", + " 'coverage': '477 / 477, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:66] [1314030:1314096]\n", + " 1 [66:150] [1314292:1314376]\n", + " 2 [150:223] [1315653:1315726]\n", + " 3 [223:333] [1320173:1320283]\n", + " 4 [333:413] [1320437:1320517]\n", + " 5 [413:477] [1324729:1324793]},\n", + " 'urn:mavedb:00000083-d-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - hnRNPA1 binding site',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '42 / 51, 82.3529411764706',\n", + " 'identity': 97.61904761904762,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [9:51] [32416489:32416531]},\n", + " 'urn:mavedb:00000003-b-2': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 RING domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '909 / 909, 100.0',\n", + " 'identity': 99.66960352422907,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [667:909] [43094618:43094860]\n", + " 1 [590:667] [43095845:43095922]\n", + " 2 [544:590] [43097243:43097289]\n", + " 3 [438:544] [43099774:43099880]\n", + " 4 [298:438] [43104121:43104261]\n", + " 5 [209:298] [43104867:43104956]\n", + " 6 [131:209] [43106455:43106533]\n", + " 7 [78:131] [43115725:43115778]\n", + " 8 [0:77] [43124016:43124093]},\n", + " 'urn:mavedb:00000027-a-1': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'PKLR promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '470 / 470, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:470] [155301394:155301864]},\n", + " 'urn:mavedb:00000062-a-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'CYP2C9',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P11712',\n", + " 'coverage': '1461 / 1461, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:162] [94938688:94938850]\n", + " 1 [162:325] [94941857:94942020]\n", + " 2 [325:475] [94942191:94942341]\n", + " 3 [475:636] [94947778:94947939]\n", + " 4 [636:813] [94949107:94949284]\n", + " 5 [813:955] [94972103:94972245]\n", + " 6 [955:1143] [94981182:94981370]\n", + " 7 [1143:1285] [94986032:94986174]\n", + " 8 [1285:1461] [94988846:94989022]},\n", + " 'urn:mavedb:00000097-e-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43106445:43106545]},\n", + " 'urn:mavedb:00000005-a-5': {'chrom': '21',\n", + " 'strand': -1,\n", + " 'target': 'CBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P35520',\n", + " 'coverage': '1656 / 1656, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1552:1656] [43053879:43053983]\n", + " 1 [1467:1552] [43056802:43056887]\n", + " 2 [1358:1467] [43058144:43058253]\n", + " 3 [1223:1358] [43058833:43058968]\n", + " 4 [1145:1223] [43059225:43059303]\n", + " 5 [1039:1145] [43060440:43060546]\n", + " 6 [954:1039] [43062310:43062395]\n", + " 7 [828:954] [43062952:43063078]\n", + " 8 [736:828] [43063899:43063991]\n", + " 9 [666:736] [43065202:43065272]\n", + " 10 [531:666] [43065386:43065521]\n", + " 11 [451:531] [43065615:43065695]\n", + " 12 [316:451] [43066242:43066377]\n", + " 13 [209:316] [43068508:43068615]\n", + " 14 [0:209] [43071984:43072193]},\n", + " 'urn:mavedb:00000033-a-1': {'chrom': '6',\n", + " 'strand': 1,\n", + " 'target': 'ZFAND3 enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '579 / 579, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:579] [37807498:37808077]},\n", + " 'urn:mavedb:00000057-d-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Ras',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P01112',\n", + " 'coverage': '495 / 495, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [447:495] [532707:532755]\n", + " 1 [287:447] [533452:533612]\n", + " 2 [108:287] [533765:533944]\n", + " 3 [0:108] [534211:534319]},\n", + " 'urn:mavedb:00000068-a-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'TP53 (P72R)',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '1180 / 1182, 99.83079526226734',\n", + " 'identity': 99.91525423728814,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1100:1180] [7669610:7669690]\n", + " 1 [993:1100] [7670608:7670715]\n", + " 2 [919:993] [7673534:7673608]\n", + " 3 [782:919] [7673700:7673837]\n", + " 4 [672:782] [7674180:7674290]\n", + " 5 [559:672] [7674858:7674971]\n", + " 6 [375:559] [7675052:7675236]\n", + " 7 [96:375] [7675993:7676272]\n", + " 8 [74:96] [7676381:7676403]\n", + " 9 [0:74] [7676520:7676594]},\n", + " 'urn:mavedb:00000049-a-6': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000104-a-1': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'PARP1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '3958 / 3958, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [3107:3958] [226360690:226361541]\n", + " 1 [2992:3107] [226361968:226362083]\n", + " 2 [2930:2992] [226363098:226363160]\n", + " 3 [2802:2930] [226363942:226364070]\n", + " 4 [2649:2802] [226365001:226365154]\n", + " 5 [2550:2649] [226365953:226366052]\n", + " 6 [2421:2550] [226367479:226367608]\n", + " 7 [2298:2421] [226368198:226368321]\n", + " 8 [2214:2298] [226370433:226370517]\n", + " 9 [2085:2214] [226374225:226374354]\n", + " 10 [1889:2085] [226377107:226377303]\n", + " 11 [1756:1889] [226379141:226379274]\n", + " 12 [1687:1756] [226379572:226379641]\n", + " 13 [1444:1687] [226379921:226380164]\n", + " 14 [1303:1444] [226381067:226381208]\n", + " 15 [1155:1303] [226383035:226383183]\n", + " 16 [978:1155] [226385503:226385680]\n", + " 17 [861:978] [226386325:226386442]\n", + " 18 [761:861] [226388655:226388755]\n", + " 19 [546:761] [226390409:226390624]\n", + " 20 [430:546] [226392198:226392314]\n", + " 21 [264:430] [226402213:226402379]\n", + " 22 [0:264] [226407809:226408073]},\n", + " 'urn:mavedb:00000083-c-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - SRSF7 (9G8) binding site',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '41 / 51, 80.3921568627451',\n", + " 'identity': 97.5609756097561,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [10:51] [32416489:32416530]},\n", + " 'urn:mavedb:00000049-a-1': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000028-a-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'RET enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '600 / 600, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:600] [43086478:43087078]},\n", + " 'urn:mavedb:00000029-a-1': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'SORT1 enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '600 / 600, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:600] [109274651:109275251]},\n", + " 'urn:mavedb:00000013-b-1': {'chrom': '6',\n", + " 'strand': -1,\n", + " 'target': 'TPMT',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P51580',\n", + " 'coverage': '738 / 738, 100.0',\n", + " 'identity': 99.86449864498645,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [625:738] [18130667:18130780]\n", + " 1 [580:625] [18132132:18132177]\n", + " 2 [494:580] [18133803:18133889]\n", + " 3 [419:494] [18138962:18139037]\n", + " 4 [366:419] [18139664:18139717]\n", + " 5 [233:366] [18143595:18143728]\n", + " 6 [140:233] [18147822:18147915]\n", + " 7 [0:140] [18148987:18149127]},\n", + " 'urn:mavedb:00000093-a-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 translation start through RING domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P38398',\n", + " 'coverage': '300 / 300, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [212:300] [43104868:43104956]\n", + " 1 [134:212] [43106455:43106533]\n", + " 2 [80:134] [43115725:43115779]\n", + " 3 [0:80] [43124016:43124096]},\n", + " 'urn:mavedb:00000001-a-3': {'chrom': '16',\n", + " 'strand': 1,\n", + " 'target': 'UBE2I',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63279',\n", + " 'coverage': '477 / 477, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:66] [1314030:1314096]\n", + " 1 [66:150] [1314292:1314376]\n", + " 2 [150:223] [1315653:1315726]\n", + " 3 [223:333] [1320173:1320283]\n", + " 4 [333:413] [1320437:1320517]\n", + " 5 [413:477] [1324729:1324793]},\n", + " 'urn:mavedb:00000045-d-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000108-a-1': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'HMBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P08397',\n", + " 'coverage': '1086 / 1086, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:33] [119085033:119085066]\n", + " 1 [33:87] [119088254:119088308]\n", + " 2 [87:160] [119088634:119088707]\n", + " 3 [160:210] [119089081:119089131]\n", + " 4 [210:266] [119089216:119089272]\n", + " 5 [266:344] [119089682:119089760]\n", + " 6 [344:422] [119089989:119090067]\n", + " 7 [422:498] [119090189:119090265]\n", + " 8 [498:612] [119091412:119091526]\n", + " 9 [612:651] [119092124:119092163]\n", + " 10 [651:771] [119092403:119092523]\n", + " 11 [771:825] [119092757:119092811]\n", + " 12 [825:912] [119092934:119093021]\n", + " 13 [912:1086] [119093109:119093283]},\n", + " 'urn:mavedb:00000096-a-1': {'chrom': '7',\n", + " 'strand': 1,\n", + " 'target': 'GCK',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '1398 / 1398, 100.0',\n", + " 'identity': 70.60085836909872,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:45] [44188908:44188953]\n", + " 1 [45:208] [44153300:44153463]\n", + " 2 [208:363] [44152270:44152425]\n", + " 3 [363:483] [44150955:44151075]\n", + " 4 [483:579] [44149968:44150064]\n", + " 5 [579:681] [44149757:44149859]\n", + " 6 [681:863] [44147649:44147831]\n", + " 7 [863:1017] [44146464:44146618]\n", + " 8 [1017:1247] [44145502:44145732]\n", + " 9 [1247:1398] [44145135:44145286]},\n", + " 'urn:mavedb:00000003-a-2': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 RING domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '909 / 909, 100.0',\n", + " 'identity': 99.66960352422907,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [667:909] [43094618:43094860]\n", + " 1 [590:667] [43095845:43095922]\n", + " 2 [544:590] [43097243:43097289]\n", + " 3 [438:544] [43099774:43099880]\n", + " 4 [298:438] [43104121:43104261]\n", + " 5 [209:298] [43104867:43104956]\n", + " 6 [131:209] [43106455:43106533]\n", + " 7 [78:131] [43115725:43115778]\n", + " 8 [0:77] [43124016:43124093]},\n", + " 'urn:mavedb:00000097-c-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 3',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43115702:43115802]},\n", + " 'urn:mavedb:00000106-a-1': {'chrom': '12',\n", + " 'strand': 0,\n", + " 'target': 'AID',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '196 / 198, 98.98989898989899',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [2:52] [8606864:8607014]\n", + " 1 [52:142] [8605215:8605485]\n", + " 2 [142:181] [8604806:8604923]\n", + " 3 [181:198] [8604286:8604337]},\n", + " 'urn:mavedb:00000083-g-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - hnRNP L binding site',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '41 / 51, 80.3921568627451',\n", + " 'identity': 97.5609756097561,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [10:51] [32416489:32416530]},\n", + " 'urn:mavedb:00000036-a-2': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'LDLRAP1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '927 / 927, 100.0',\n", + " 'identity': 99.78425026968716,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:88] [25543698:25543786]\n", + " 1 [88:231] [25553921:25554064]\n", + " 2 [231:344] [25554859:25554972]\n", + " 3 [344:459] [25557152:25557267]\n", + " 4 [459:532] [25562643:25562716]\n", + " 5 [532:616] [25563069:25563153]\n", + " 6 [616:747] [25563660:25563791]\n", + " 7 [747:782] [25565172:25565207]\n", + " 8 [782:927] [25566847:25566992]},\n", + " 'urn:mavedb:00000097-t-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 20',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43051039:43051139]},\n", + " 'urn:mavedb:00000097-l-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 16',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '108 / 108, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:108] [43067597:43067705]},\n", + " 'urn:mavedb:00000094-a-11': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000027-b-1': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'PKLR promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '470 / 470, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:470] [155301394:155301864]},\n", + " 'urn:mavedb:00000002-a-2': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'hYAP65 WW domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P46937',\n", + " 'coverage': '102 / 102, 100.0',\n", + " 'identity': 77.45098039215686,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:60] [102114329:102114389]\n", + " 1 [60:102] [102162450:102162492]},\n", + " 'urn:mavedb:00000061-c-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000035-a-2': {'chrom': '5',\n", + " 'strand': 1,\n", + " 'target': 'HMGCR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '2667 / 2667, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:165] [75342605:75342770]\n", + " 1 [165:277] [75343852:75343964]\n", + " 2 [277:365] [75344244:75344332]\n", + " 3 [365:450] [75345573:75345658]\n", + " 4 [450:556] [75347203:75347309]\n", + " 5 [556:663] [75350041:75350148]\n", + " 6 [663:780] [75350257:75350374]\n", + " 7 [780:941] [75350788:75350949]\n", + " 8 [941:1189] [75351067:75351315]\n", + " 9 [1189:1368] [75351423:75351602]\n", + " 10 [1368:1563] [75354502:75354697]\n", + " 11 [1563:1722] [75355055:75355214]\n", + " 12 [1722:1880] [75355364:75355522]\n", + " 13 [1880:1986] [75356342:75356448]\n", + " 14 [1986:2157] [75358656:75358827]\n", + " 15 [2157:2298] [75359169:75359310]\n", + " 16 [2298:2457] [75359397:75359556]\n", + " 17 [2457:2612] [75359984:75360139]\n", + " 18 [2612:2667] [75360287:75360342]},\n", + " 'urn:mavedb:00000031-b-1': {'chrom': '5',\n", + " 'strand': 1,\n", + " 'target': 'TERT promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '259 / 259, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:259] [1294988:1295247]},\n", + " 'urn:mavedb:00000035-a-3': {'chrom': '5',\n", + " 'strand': 1,\n", + " 'target': 'HMGCR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '2667 / 2667, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:165] [75342605:75342770]\n", + " 1 [165:277] [75343852:75343964]\n", + " 2 [277:365] [75344244:75344332]\n", + " 3 [365:450] [75345573:75345658]\n", + " 4 [450:556] [75347203:75347309]\n", + " 5 [556:663] [75350041:75350148]\n", + " 6 [663:780] [75350257:75350374]\n", + " 7 [780:941] [75350788:75350949]\n", + " 8 [941:1189] [75351067:75351315]\n", + " 9 [1189:1368] [75351423:75351602]\n", + " 10 [1368:1563] [75354502:75354697]\n", + " 11 [1563:1722] [75355055:75355214]\n", + " 12 [1722:1880] [75355364:75355522]\n", + " 13 [1880:1986] [75356342:75356448]\n", + " 14 [1986:2157] [75358656:75358827]\n", + " 15 [2157:2298] [75359169:75359310]\n", + " 16 [2298:2457] [75359397:75359556]\n", + " 17 [2457:2612] [75359984:75360139]\n", + " 18 [2612:2667] [75360287:75360342]},\n", + " 'urn:mavedb:00000006-a-1': {'chrom': '9',\n", + " 'strand': 1,\n", + " 'target': 'ALDOB enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '259 / 259, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:259] [101433287:101433546]},\n", + " 'urn:mavedb:00000094-a-13': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000045-h-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000051-c-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'Glycophorin A',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P02724',\n", + " 'coverage': '44 / 45, 97.77777777777777',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:44] [144116887:144116931]},\n", + " 'urn:mavedb:00000097-u-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 21',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '105 / 105, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:105] [43049102:43049207]},\n", + " 'urn:mavedb:00000097-d-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 3',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43115702:43115802]},\n", + " 'urn:mavedb:00000036-a-1': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'LDLRAP1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '927 / 927, 100.0',\n", + " 'identity': 99.78425026968716,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:88] [25543698:25543786]\n", + " 1 [88:231] [25553921:25554064]\n", + " 2 [231:344] [25554859:25554972]\n", + " 3 [344:459] [25557152:25557267]\n", + " 4 [459:532] [25562643:25562716]\n", + " 5 [532:616] [25563069:25563153]\n", + " 6 [616:747] [25563660:25563791]\n", + " 7 [747:782] [25565172:25565207]\n", + " 8 [782:927] [25566847:25566992]},\n", + " 'urn:mavedb:00000105-a-1': {'chrom': 'NA',\n", + " 'strand': 'NA',\n", + " 'target': 'NA',\n", + " 'target_type': 'NA',\n", + " 'uniprot': 'NA',\n", + " 'coverage': 'NA',\n", + " 'identity': 'NA',\n", + " 'hits': query_ranges hit_ranges\n", + " 0 N N\n", + " 1 A A},\n", + " 'urn:mavedb:00000081-a-2': {'chrom': '17',\n", + " 'strand': 0,\n", + " 'target': 'BRCA1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '1863 / 1863, 100.0',\n", + " 'identity': 99.94623655913979,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:26] [43124018:43124096]\n", + " 1 [27:45] [43115724:43115778]\n", + " 2 [45:70] [43106457:43106532]\n", + " 3 [70:100] [43104868:43104958]\n", + " 4 [101:147] [43104121:43104259]\n", + " 5 [147:181] [43099778:43099880]\n", + " 6 [181:197] [43097245:43097293]\n", + " 7 [197:223] [43095846:43095924]\n", + " 8 [223:1365] [43091435:43094861]\n", + " 9 [1365:1395] [43090943:43091033]\n", + " 10 [1395:1451] [43082407:43082575]\n", + " 11 [1451:1494] [43076489:43076618]\n", + " 12 [1494:1558] [43074331:43074523]\n", + " 13 [1558:1662] [43070927:43071239]\n", + " 14 [1662:1691] [43067608:43067695]\n", + " 15 [1691:1717] [43063874:43063952]\n", + " 16 [1718:1731] [43063332:43063371]\n", + " 17 [1731:1759] [43057051:43057135]\n", + " 18 [1759:1777] [43051063:43051117]\n", + " 19 [1777:1802] [43049120:43049195]\n", + " 20 [1802:1822] [43047643:43047703]\n", + " 21 [1822:1863] [43045680:43045803]},\n", + " 'urn:mavedb:00000053-a-2': {'chrom': '17',\n", + " 'strand': 1,\n", + " 'target': 'PSD95 PDZ3',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P78352',\n", + " 'coverage': '249 / 249, 100.0',\n", + " 'identity': 74.6987951807229,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:156] [7196753:7196909]\n", + " 1 [156:249] [7196479:7196572]},\n", + " 'urn:mavedb:00000060-a-1': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'TARDBP',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q13148',\n", + " 'coverage': '1242 / 1242, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:238] [11013727:11013965]\n", + " 1 [238:402] [11016843:11017007]\n", + " 2 [402:543] [11018732:11018873]\n", + " 3 [543:714] [11020428:11020599]\n", + " 4 [714:1242] [11022123:11022651]},\n", + " 'urn:mavedb:00000013-a-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'PTEN',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P60484',\n", + " 'coverage': '1212 / 1212, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:79] [87864469:87864548]\n", + " 1 [79:164] [87894024:87894109]\n", + " 2 [164:209] [87925512:87925557]\n", + " 3 [209:253] [87931045:87931089]\n", + " 4 [253:492] [87933012:87933251]\n", + " 5 [492:634] [87952117:87952259]\n", + " 6 [634:801] [87957852:87958019]\n", + " 7 [801:1026] [87960893:87961118]\n", + " 8 [1026:1212] [87965286:87965472]},\n", + " 'urn:mavedb:00000022-a-1': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'IRF6 enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '601 / 601, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:601] [209815789:209816390]},\n", + " 'urn:mavedb:00000097-z-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 23',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '108 / 108, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:108] [43045704:43045812]},\n", + " 'urn:mavedb:00000094-a-9': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000045-e-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000097-j-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 15',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '106 / 106, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:106] [43070917:43071023]},\n", + " 'urn:mavedb:00000047-b-1': {'chrom': '3',\n", + " 'strand': 1,\n", + " 'target': 'CCR5',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P51681',\n", + " 'coverage': '1053 / 1053, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:1053] [46372905:46373958]},\n", + " 'urn:mavedb:00000003-b-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 RING domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '909 / 909, 100.0',\n", + " 'identity': 99.66960352422907,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [667:909] [43094618:43094860]\n", + " 1 [590:667] [43095845:43095922]\n", + " 2 [544:590] [43097243:43097289]\n", + " 3 [438:544] [43099774:43099880]\n", + " 4 [298:438] [43104121:43104261]\n", + " 5 [209:298] [43104867:43104956]\n", + " 6 [131:209] [43106455:43106533]\n", + " 7 [78:131] [43115725:43115778]\n", + " 8 [0:77] [43124016:43124093]},\n", + " 'urn:mavedb:00000054-a-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'PTEN',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P60484',\n", + " 'coverage': '1212 / 1212, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:79] [87864469:87864548]\n", + " 1 [79:164] [87894024:87894109]\n", + " 2 [164:209] [87925512:87925557]\n", + " 3 [209:253] [87931045:87931089]\n", + " 4 [253:492] [87933012:87933251]\n", + " 5 [492:634] [87952117:87952259]\n", + " 6 [634:801] [87957852:87958019]\n", + " 7 [801:1026] [87960893:87961118]\n", + " 8 [1026:1212] [87965286:87965472]},\n", + " 'urn:mavedb:00000061-a-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000047-a-1': {'chrom': '3',\n", + " 'strand': 1,\n", + " 'target': 'CCR5',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P51681',\n", + " 'coverage': '1053 / 1053, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:1053] [46372905:46373958]},\n", + " 'urn:mavedb:00000035-a-1': {'chrom': '5',\n", + " 'strand': 1,\n", + " 'target': 'HMGCR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '2667 / 2667, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:165] [75342605:75342770]\n", + " 1 [165:277] [75343852:75343964]\n", + " 2 [277:365] [75344244:75344332]\n", + " 3 [365:450] [75345573:75345658]\n", + " 4 [450:556] [75347203:75347309]\n", + " 5 [556:663] [75350041:75350148]\n", + " 6 [663:780] [75350257:75350374]\n", + " 7 [780:941] [75350788:75350949]\n", + " 8 [941:1189] [75351067:75351315]\n", + " 9 [1189:1368] [75351423:75351602]\n", + " 10 [1368:1563] [75354502:75354697]\n", + " 11 [1563:1722] [75355055:75355214]\n", + " 12 [1722:1880] [75355364:75355522]\n", + " 13 [1880:1986] [75356342:75356448]\n", + " 14 [1986:2157] [75358656:75358827]\n", + " 15 [2157:2298] [75359169:75359310]\n", + " 16 [2298:2457] [75359397:75359556]\n", + " 17 [2457:2612] [75359984:75360139]\n", + " 18 [2612:2667] [75360287:75360342]},\n", + " 'urn:mavedb:00000015-a-1': {'chrom': 'X',\n", + " 'strand': 1,\n", + " 'target': 'F9 promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '303 / 303, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:303] [139530462:139530765]},\n", + " 'urn:mavedb:00000078-b-1': {'chrom': '16',\n", + " 'strand': 0,\n", + " 'target': 'VKOR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '163 / 163, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:57] [31094558:31094729]\n", + " 1 [57:94] [31093312:31093423]\n", + " 2 [94:163] [31091136:31091343]},\n", + " 'urn:mavedb:00000025-a-1': {'chrom': '8',\n", + " 'strand': 1,\n", + " 'target': 'MYC enhancer (rs6983267)',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '600 / 600, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:600] [127400828:127401428]},\n", + " 'urn:mavedb:00000045-l-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000065-a-1': {'chrom': '9',\n", + " 'strand': 1,\n", + " 'target': 'NCS1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '573 / 573, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:64] [130172663:130172727]\n", + " 1 [64:89] [130200957:130200982]\n", + " 2 [89:228] [130217831:130217970]\n", + " 3 [228:307] [130219724:130219803]\n", + " 4 [307:396] [130222649:130222738]\n", + " 5 [396:474] [130223081:130223159]\n", + " 6 [474:573] [130226388:130226487]},\n", + " 'urn:mavedb:00000046-a-3': {'chrom': '3',\n", + " 'strand': 1,\n", + " 'target': 'CD86',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42081',\n", + " 'coverage': '81 / 81, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:81] [122109290:122109371]},\n", + " 'urn:mavedb:00000068-c-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'TP53 (P72R)',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '1180 / 1182, 99.83079526226734',\n", + " 'identity': 99.91525423728814,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1100:1180] [7669610:7669690]\n", + " 1 [993:1100] [7670608:7670715]\n", + " 2 [919:993] [7673534:7673608]\n", + " 3 [782:919] [7673700:7673837]\n", + " 4 [672:782] [7674180:7674290]\n", + " 5 [559:672] [7674858:7674971]\n", + " 6 [375:559] [7675052:7675236]\n", + " 7 [96:375] [7675993:7676272]\n", + " 8 [74:96] [7676381:7676403]\n", + " 9 [0:74] [7676520:7676594]},\n", + " 'urn:mavedb:00000005-a-2': {'chrom': '21',\n", + " 'strand': -1,\n", + " 'target': 'CBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P35520',\n", + " 'coverage': '1656 / 1656, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1552:1656] [43053879:43053983]\n", + " 1 [1467:1552] [43056802:43056887]\n", + " 2 [1358:1467] [43058144:43058253]\n", + " 3 [1223:1358] [43058833:43058968]\n", + " 4 [1145:1223] [43059225:43059303]\n", + " 5 [1039:1145] [43060440:43060546]\n", + " 6 [954:1039] [43062310:43062395]\n", + " 7 [828:954] [43062952:43063078]\n", + " 8 [736:828] [43063899:43063991]\n", + " 9 [666:736] [43065202:43065272]\n", + " 10 [531:666] [43065386:43065521]\n", + " 11 [451:531] [43065615:43065695]\n", + " 12 [316:451] [43066242:43066377]\n", + " 13 [209:316] [43068508:43068615]\n", + " 14 [0:209] [43071984:43072193]},\n", + " 'urn:mavedb:00000061-e-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000019-a-1': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'HBG1 promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '274 / 274, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:274] [5249804:5250078]},\n", + " 'urn:mavedb:00000055-b-1': {'chrom': '13',\n", + " 'strand': 1,\n", + " 'target': 'NUDT15',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9NV35',\n", + " 'coverage': '495 / 495, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:158] [48037746:48037904]\n", + " 1 [158:355] [48040919:48041116]\n", + " 2 [355:495] [48045659:48045799]},\n", + " 'urn:mavedb:00000057-a-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Ras',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P01112',\n", + " 'coverage': '495 / 495, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [447:495] [532707:532755]\n", + " 1 [287:447] [533452:533612]\n", + " 2 [108:287] [533765:533944]\n", + " 3 [0:108] [534211:534319]},\n", + " 'urn:mavedb:00000097-n-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 17',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '98 / 98, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:98] [43063863:43063961]},\n", + " 'urn:mavedb:00000001-d-2': {'chrom': '7',\n", + " 'strand': -1,\n", + " 'target': 'TPK1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9H3S4',\n", + " 'coverage': '585 / 585, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [466:585] [144453544:144453663]\n", + " 1 [354:466] [144548490:144548602]\n", + " 2 [258:354] [144623165:144623261]\n", + " 3 [185:258] [144648806:144648879]\n", + " 4 [115:185] [144682908:144682978]\n", + " 5 [43:115] [144765879:144765951]\n", + " 6 [0:43] [144835559:144835602]},\n", + " 'urn:mavedb:00000017-a-1': {'chrom': '22',\n", + " 'strand': 1,\n", + " 'target': 'GP1BB promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '385 / 385, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:385] [19723265:19723650]},\n", + " 'urn:mavedb:00000005-a-3': {'chrom': '21',\n", + " 'strand': -1,\n", + " 'target': 'CBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P35520',\n", + " 'coverage': '1656 / 1656, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1552:1656] [43053879:43053983]\n", + " 1 [1467:1552] [43056802:43056887]\n", + " 2 [1358:1467] [43058144:43058253]\n", + " 3 [1223:1358] [43058833:43058968]\n", + " 4 [1145:1223] [43059225:43059303]\n", + " 5 [1039:1145] [43060440:43060546]\n", + " 6 [954:1039] [43062310:43062395]\n", + " 7 [828:954] [43062952:43063078]\n", + " 8 [736:828] [43063899:43063991]\n", + " 9 [666:736] [43065202:43065272]\n", + " 10 [531:666] [43065386:43065521]\n", + " 11 [451:531] [43065615:43065695]\n", + " 12 [316:451] [43066242:43066377]\n", + " 13 [209:316] [43068508:43068615]\n", + " 14 [0:209] [43071984:43072193]},\n", + " 'urn:mavedb:00000083-f-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - hnRNP I (PTB) binding site',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '41 / 51, 80.3921568627451',\n", + " 'identity': 97.5609756097561,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [10:51] [32416489:32416530]},\n", + " 'urn:mavedb:00000031-d-1': {'chrom': '5',\n", + " 'strand': 1,\n", + " 'target': 'TERT promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '259 / 259, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:259] [1294988:1295247]},\n", + " 'urn:mavedb:00000106-c-1': {'chrom': '12',\n", + " 'strand': 0,\n", + " 'target': 'AID',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '196 / 198, 98.98989898989899',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [2:52] [8606864:8607014]\n", + " 1 [52:142] [8605215:8605485]\n", + " 2 [142:181] [8604806:8604923]\n", + " 3 [181:198] [8604286:8604337]},\n", + " 'urn:mavedb:00000020-a-1': {'chrom': '20',\n", + " 'strand': 1,\n", + " 'target': 'HNF4A promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '285 / 285, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:285] [44355519:44355804]},\n", + " 'urn:mavedb:00000007-a-1': {'chrom': '2',\n", + " 'strand': 1,\n", + " 'target': 'ECR11 enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '620 / 620, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:620] [169082571:169083191]},\n", + " 'urn:mavedb:00000045-b-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000048-b-1': {'chrom': '2',\n", + " 'strand': -1,\n", + " 'target': 'CXCR4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P61073',\n", + " 'coverage': '1041 / 1053, 98.86039886039886',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [12:1053] [136114871:136115912]},\n", + " 'urn:mavedb:00000095-a-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'CYP2C9',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '1470 / 1470, 100.0',\n", + " 'identity': 75.03401360544217,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:168] [94938682:94938850]\n", + " 1 [168:334] [94941857:94942023]\n", + " 2 [334:479] [94942194:94942339]\n", + " 3 [479:642] [94947776:94947939]\n", + " 4 [642:819] [94949107:94949284]\n", + " 5 [819:961] [94972103:94972245]\n", + " 6 [961:1149] [94981182:94981370]\n", + " 7 [1149:1291] [94986032:94986174]\n", + " 8 [1291:1470] [94988846:94989025]},\n", + " 'urn:mavedb:00000016-a-1': {'chrom': '9',\n", + " 'strand': 1,\n", + " 'target': 'FOXE1 promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '600 / 600, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:600] [97853254:97853854]},\n", + " 'urn:mavedb:00000029-b-1': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'SORT1 enhancer (flipped)',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '600 / 601, 99.83361064891847',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1:601] [109274651:109275251]},\n", + " 'urn:mavedb:00000049-a-5': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000097-y-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 23',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '108 / 108, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:108] [43045704:43045812]},\n", + " 'urn:mavedb:00000005-a-1': {'chrom': '21',\n", + " 'strand': -1,\n", + " 'target': 'CBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P35520',\n", + " 'coverage': '1656 / 1656, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1552:1656] [43053879:43053983]\n", + " 1 [1467:1552] [43056802:43056887]\n", + " 2 [1358:1467] [43058144:43058253]\n", + " 3 [1223:1358] [43058833:43058968]\n", + " 4 [1145:1223] [43059225:43059303]\n", + " 5 [1039:1145] [43060440:43060546]\n", + " 6 [954:1039] [43062310:43062395]\n", + " 7 [828:954] [43062952:43063078]\n", + " 8 [736:828] [43063899:43063991]\n", + " 9 [666:736] [43065202:43065272]\n", + " 10 [531:666] [43065386:43065521]\n", + " 11 [451:531] [43065615:43065695]\n", + " 12 [316:451] [43066242:43066377]\n", + " 13 [209:316] [43068508:43068615]\n", + " 14 [0:209] [43071984:43072193]},\n", + " 'urn:mavedb:00000097-a-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 2',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '106 / 106, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:106] [43124012:43124118]},\n", + " 'urn:mavedb:00000003-a-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 RING domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '909 / 909, 100.0',\n", + " 'identity': 99.66960352422907,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [667:909] [43094618:43094860]\n", + " 1 [590:667] [43095845:43095922]\n", + " 2 [544:590] [43097243:43097289]\n", + " 3 [438:544] [43099774:43099880]\n", + " 4 [298:438] [43104121:43104261]\n", + " 5 [209:298] [43104867:43104956]\n", + " 6 [131:209] [43106455:43106533]\n", + " 7 [78:131] [43115725:43115778]\n", + " 8 [0:77] [43124016:43124093]},\n", + " 'urn:mavedb:00000030-a-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'TCF7L2 enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '600 / 600, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:600] [112998239:112998839]},\n", + " 'urn:mavedb:00000005-a-4': {'chrom': '21',\n", + " 'strand': -1,\n", + " 'target': 'CBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P35520',\n", + " 'coverage': '1656 / 1656, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1552:1656] [43053879:43053983]\n", + " 1 [1467:1552] [43056802:43056887]\n", + " 2 [1358:1467] [43058144:43058253]\n", + " 3 [1223:1358] [43058833:43058968]\n", + " 4 [1145:1223] [43059225:43059303]\n", + " 5 [1039:1145] [43060440:43060546]\n", + " 6 [954:1039] [43062310:43062395]\n", + " 7 [828:954] [43062952:43063078]\n", + " 8 [736:828] [43063899:43063991]\n", + " 9 [666:736] [43065202:43065272]\n", + " 10 [531:666] [43065386:43065521]\n", + " 11 [451:531] [43065615:43065695]\n", + " 12 [316:451] [43066242:43066377]\n", + " 13 [209:316] [43068508:43068615]\n", + " 14 [0:209] [43071984:43072193]},\n", + " 'urn:mavedb:00000034-a-1': {'chrom': '7',\n", + " 'strand': 1,\n", + " 'target': 'ZRS enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '485 / 486, 99.79423868312757',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:485] [156791118:156791603]},\n", + " 'urn:mavedb:00000023-a-2': {'chrom': '19',\n", + " 'strand': 1,\n", + " 'target': 'LDLR promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '318 / 318, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:318] [11089230:11089548]},\n", + " 'urn:mavedb:00000002-a-1': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'hYAP65 WW domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P46937',\n", + " 'coverage': '102 / 102, 100.0',\n", + " 'identity': 77.45098039215686,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:60] [102114329:102114389]\n", + " 1 [60:102] [102162450:102162492]},\n", + " 'urn:mavedb:00000107-a-1': {'chrom': '9',\n", + " 'strand': 0,\n", + " 'target': 'PSAT1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '370 / 370, 100.0',\n", + " 'identity': 99.9096657633243,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:20] [78297210:78297270]\n", + " 1 [20:40] [78300601:78300661]\n", + " 2 [40:64] [78301952:78302024]\n", + " 3 [64:132] [78304735:78304939]\n", + " 4 [133:189] [78306315:78306483]\n", + " 5 [189:245] [78308410:78308578]\n", + " 6 [245:290] [78317670:78317805]\n", + " 7 [290:335] [78328051:78328186]\n", + " 8 [335:370] [78328978:78329083]},\n", + " 'urn:mavedb:00000103-d-1': {'chrom': '22',\n", + " 'strand': 0,\n", + " 'target': 'MAPK1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '360 / 360, 100.0',\n", + " 'identity': 99.9071494893222,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:39] [21867323:21867440]\n", + " 1 [40:101] [21807662:21807845]\n", + " 2 [101:164] [21805849:21806038]\n", + " 3 [164:203] [21799011:21799128]\n", + " 4 [203:241] [21788694:21788808]\n", + " 5 [241:285] [21788257:21788389]\n", + " 6 [285:322] [21772872:21772983]\n", + " 7 [322:360] [21769206:21769320]},\n", + " 'urn:mavedb:00000029-a-2': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'SORT1 enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '600 / 600, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:600] [109274651:109275251]},\n", + " 'urn:mavedb:00000061-b-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000097-q-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 19',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '104 / 104, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [43057041:43057145]}}" + ] + }, + "execution_count": 8, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "mave_blat" + ] + }, + { + "cell_type": "code", + "execution_count": 9, + "id": "c7b5141f", + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "{'urn:mavedb:00000041-a-1': ['NP_938033.1',\n", + " 269,\n", + " 'urn:mavedb:00000041-a-1',\n", + " True],\n", + " 'urn:mavedb:00000048-a-1': ['NP_003458.1',\n", + " 0,\n", + " 'urn:mavedb:00000048-a-1',\n", + " True],\n", + 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" 0,\n", + " 'urn:mavedb:00000049-a-5',\n", + " True],\n", + " 'urn:mavedb:00000097-y-1': ['NP_009225.1',\n", + " -1,\n", + " 'urn:mavedb:00000097-y-1',\n", + " False],\n", + " 'urn:mavedb:00000005-a-1': ['NP_000062.1',\n", + " 0,\n", + " 'urn:mavedb:00000005-a-1',\n", + " True],\n", + " 'urn:mavedb:00000097-a-1': [],\n", + " 'urn:mavedb:00000003-a-1': ['NP_009225.1',\n", + " 1,\n", + " 'urn:mavedb:00000003-a-1',\n", + " False],\n", + " 'urn:mavedb:00000005-a-4': ['NP_000062.1',\n", + " 0,\n", + " 'urn:mavedb:00000005-a-4',\n", + " True],\n", + " 'urn:mavedb:00000002-a-1': ['NP_001123617.1',\n", + " 169,\n", + " 'urn:mavedb:00000002-a-1',\n", + " True],\n", + " 'urn:mavedb:00000107-a-1': ['NP_478059.1',\n", + " 0,\n", + " 'urn:mavedb:00000107-a-1',\n", + " True],\n", + " 'urn:mavedb:00000103-d-1': ['NP_002736.3',\n", + " 0,\n", + " 'urn:mavedb:00000103-d-1',\n", + " True],\n", + " 'urn:mavedb:00000061-b-1': ['NP_002871.1',\n", + " 51,\n", + " 'urn:mavedb:00000061-b-1',\n", + " True],\n", + " 'urn:mavedb:00000097-q-1': []}" + ] + }, + "execution_count": 9, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "mappings_dict" + ] + }, + { + "cell_type": "code", + "execution_count": 10, + "id": "634571d9", + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "{'urn:mavedb:00000041-a-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.K7JuB0HAfN875G9YyQvnjWCH1STCY... \n", + " 1 {'id': 'ga4gh:VA.14HDZPvvZuCWWhT_OhE-Yvvc89gvk... \n", + " 2 {'id': 'ga4gh:VA._wx37BU-VVTbvg0zWgwp2Ym55iMVb... \n", + " 3 {'id': 'ga4gh:VA.EcsLmgd4pHc1uejRP34CxQ0setRif... \n", + " 4 {'id': 'ga4gh:VA.AsE39Yu8GinT0QVRkC8cs486_m68C... \n", + " ... ... \n", + " 3501 {'id': 'ga4gh:VA.AjXbF7b5sjQwteZlMKSmabYsqJHvB... \n", + " 3502 {'id': 'ga4gh:VA.vL2mlC4h7ZTEcJML6XY8LQGmc6Ph6... \n", + " 3503 {'id': 'ga4gh:VA.i4aHKTjGaCqm82v_sAbhJqi_pJ5o7... \n", + " 3504 {'id': 'ga4gh:VA.dVXd7aZ85GIcK0mLQ2eYqcIyE7EO0... \n", + " 3505 {'id': 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{'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1964 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " \n", + " mapped \n", + " 0 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 2 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 3 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 4 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " ... ... \n", + " 1960 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1961 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1962 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1963 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1964 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " \n", + " [1965 rows x 2 columns],\n", + " 'urn:mavedb:00000055-0-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.PZ4TzypyhPOi0pa7HyfiX7ugDCBUS... \n", + " 1 {'id': 'ga4gh:VA.mt57gu1pxh-LFSsgofp3ebve-0LJw... \n", 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columns],\n", + " 'urn:mavedb:00000072-a-1': pre_mapping \\\n", + " 0 {'definition': 'P01857:p.Lys99Ter', 'type': 'T... \n", + " 1 {'definition': 'P01857:p.Gln98Ter', 'type': 'T... \n", + " 2 {'definition': 'P01857:p.Thr97Ter', 'type': 'T... \n", + " 3 {'definition': 'P01857:p.Tyr96Ter', 'type': 'T... \n", + " 4 {'definition': 'P01857:p.Glu90Ter', 'type': 'T... \n", + " .. ... \n", + " 693 {'definition': 'P01857:p.Val8Ala', 'type': 'Te... \n", + " 694 {'definition': 'P01857:p.Pro6Ala', 'type': 'Te... \n", + " 695 {'definition': 'P01857:p.Glu5Ala', 'type': 'Te... \n", + " 696 {'definition': 'P01857:p.Pro3Ala', 'type': 'Te... \n", + " 697 {'definition': 'P01857:p.Gly1Ala', 'type': 'Te... \n", + " \n", + " mapped \n", + " 0 {'definition': 'P01857:p.Lys99Ter', 'type': 'T... \n", + " 1 {'definition': 'P01857:p.Gln98Ter', 'type': 'T... \n", + " 2 {'definition': 'P01857:p.Thr97Ter', 'type': 'T... \n", + " 3 {'definition': 'P01857:p.Tyr96Ter', 'type': 'T... \n", + " 4 {'definition': 'P01857:p.Glu90Ter', 'type': 'T... \n", + " .. ... \n", + " 693 {'definition': 'P01857:p.Val8Ala', 'type': 'Te... \n", + " 694 {'definition': 'P01857:p.Pro6Ala', 'type': 'Te... \n", + " 695 {'definition': 'P01857:p.Glu5Ala', 'type': 'Te... \n", + " 696 {'definition': 'P01857:p.Pro3Ala', 'type': 'Te... \n", + " 697 {'definition': 'P01857:p.Gly1Ala', 'type': 'Te... \n", + " \n", + " [698 rows x 2 columns],\n", + " 'urn:mavedb:00000095-b-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.YacijvKtg-szZIKCDNdENg96brStR... \n", + " 1 {'id': 'ga4gh:VA.Gd4m35Bnopq_bW6eIb6v9RpeuX3CU... \n", + " 2 {'id': 'ga4gh:VA.U8kgyImE4IfXxCXRoXMZYP9XQEttk... \n", + " 3 {'id': 'ga4gh:VA.3BdtFlWQ45rxxadgTb5fKNLjyA7D4... \n", + " 4 {'id': 'ga4gh:VA.bdAiS2wARSjZHohwj8b4lnyoGCNq2... \n", + " ... ... \n", + " 6815 {'id': 'ga4gh:VA.DblkfpjJ0UIaof-NPa_qEgTPUB1hS... \n", + " 6816 {'id': 'ga4gh:VA.Jh2qWWvTTZgZaCP0etLpxm1WWelaj... \n", + " 6817 {'id': 'ga4gh:VA.lV1Rh028vVAda8f-UQA4MoX0xo-jj... \n", + " 6818 {'id': 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'ga4gh:VA.WUD7hZ-4dKcNb3tk66dt2VD4nPlxB... \n", + " .. ... \n", + " 116 {'id': 'ga4gh:VA.HtMHDW9qvBJTGV2TKrs1mon3WLChs... \n", + " 117 {'id': 'ga4gh:VA.ht3kZs-MI8ALoIvCc_7yX2R5CxtT9... \n", + " 118 {'id': 'ga4gh:VA.X5xHNrLJaXK5LkU9J008YBhC4WQCc... \n", + " 119 {'id': 'ga4gh:VA.8KvomdTpMILf-lglSGmXG-nYP8N3-... \n", + " 120 {'id': 'ga4gh:VA.SmZ8XsBsagWLNi-wnkErrUD_S3fIC... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.JrAZJqX-RizXM4lcw6Dju8Vm1iNR_... \n", + " 1 {'id': 'ga4gh:VA.qlLOI0Ll5WFGofrkEkuryPVQT0U4I... \n", + " 2 {'id': 'ga4gh:VA.OpGLgysA-5oFkwRCbtIBJ0jy81v1Q... \n", + " 3 {'id': 'ga4gh:VA.xw4UCSxpj_Gr1uP0hzeFqe18Dhe6K... \n", + " 4 {'id': 'ga4gh:VA.SOZXohIq7QCQY_kda8VIL7M_SWPVo... \n", + " .. ... \n", + " 116 {'id': 'ga4gh:VA.zN9HtNUS-7sb1fK8EUxdC3PDJikYz... \n", + " 117 {'id': 'ga4gh:VA.mE-vrP7nV51Xdjj_-1KoVkzOukoTW... \n", + " 118 {'id': 'ga4gh:VA.RDLb4XHwjQK515Q-w4wmHqUKY-LGc... \n", + " 119 {'id': 'ga4gh:VA.jwkBIUox4BG0Zx2JyCLXs7pDrBx1u... \n", + " 120 {'id': 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columns],\n", + " 'urn:mavedb:00000097-d-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.kznoVx4h-WaHRLavc6NelJggTiAAu... \n", + " 1 {'id': 'ga4gh:VA.5GOvFG6LIIq_o0VdcE10wowlWFo1F... \n", + " 2 {'id': 'ga4gh:VA.AuRHRhmFy5gqAaI_6RESjdyyPZQty... \n", + " 3 {'id': 'ga4gh:VA.oVw-3INT49d3Ro9-F7hylI6MOQzEX... \n", + " 4 {'id': 'ga4gh:VA.5xHYgQLGum_x8zX0p75xzCX0ynu0B... \n", + " .. ... \n", + " 150 {'id': 'ga4gh:VA.nRz_DHZOQ5tjaUnNRSH59WMb6cTYe... \n", + " 151 {'id': 'ga4gh:VA.Oin0Wg9nIxFJj0av-Vu37fMtI8LaI... \n", + " 152 {'id': 'ga4gh:VA.kq6x2OsvSCyBL2Sg8gIH83P1nRO6b... \n", + " 153 {'id': 'ga4gh:VA.DuqOPjEoYw18UcPTK2_Q--duxJZ8W... \n", + " 154 {'id': 'ga4gh:VA.BnPmV9yDNJMrBHTtOoS7tQNnlFClR... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.kznoVx4h-WaHRLavc6NelJggTiAAu... \n", + " 1 {'id': 'ga4gh:VA.5GOvFG6LIIq_o0VdcE10wowlWFo1F... \n", + " 2 {'id': 'ga4gh:VA.AuRHRhmFy5gqAaI_6RESjdyyPZQty... \n", + " 3 {'id': 'ga4gh:VA.oVw-3INT49d3Ro9-F7hylI6MOQzEX... \n", + " 4 {'id': 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] + }, + "execution_count": 10, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "dna_or_prot = {}\n", + "for key in vrs_mappings_coding:\n", + " if len(vrs_mappings_coding[key]) > 1: # take genomic, first 10 rows\n", + " vrs_mappings_coding[key] = vrs_mappings_coding[key][1]\n", + " #vrs_mappings_coding[key] = ex_mappings[key].head(10)\n", + " dna_or_prot[key] = 'dna'\n", + " else:\n", + " vrs_mappings_coding[key] = vrs_mappings_coding[key][0]\n", + " #ex_mappings[key] = ex_mappings[key].head(10)\n", + " dna_or_prot[key] = 'protein'\n", + "vrs_mappings_coding" + ] + }, + { + "cell_type": "code", + "execution_count": 11, + "id": "476e3e74", + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "{'urn:mavedb:00000018-a-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.aL2vPNTYMmCg2AlvBxo6Z2JKkDSS7... \n", + " 1 {'id': 'ga4gh:VA.8343MCMO9Ou--W6di93xasf9G47fj... \n", + " 2 {'id': 'ga4gh:VA.YYoWQwhF42lOv1ryIwca-_wIAxeE8... \n", + " 3 {'id': 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pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.lnnQZhpB3Ycq2rf9hIBYBSCmFdg_H... \n", + " 1 {'id': 'ga4gh:VA.GuhVTvxU6LBAg7GLFAQ1yy91_fEfP... \n", + " 2 {'id': 'ga4gh:VA.1u6VaIT9Igh1k7oYnEhWx9SPtS2Ci... \n", + " 3 {'id': 'ga4gh:VA.pB0QwXEkSmrPF-6diuBS8Tma-doql... \n", + " 4 {'id': 'ga4gh:VA.SN_NMiS8g9QYwowlU_3EezMDEEAlY... \n", + " ... ... \n", + " 1450 {'id': 'ga4gh:VA.M79IqBqvmsFipEEHSXuRvQFuXcM_F... \n", + " 1451 {'id': 'ga4gh:VA.TAoKnneo-B2pp2j-d8sCLKJ6liKYe... \n", + " 1452 {'id': 'ga4gh:VA.3IhYb4oC2dtDDSI6OfX02NKOISlrr... \n", + " 1453 {'id': 'ga4gh:VA.5sOpVj2A5IOWMkm7e0frQ7MVyBYsO... \n", + " 1454 {'id': 'ga4gh:VA.ibBOyEFZKv_snB8BRImoIfIl52J5-... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.BG_JeFI3MvY8-2uscgDiA7V3gUBQr... \n", + " 1 {'id': 'ga4gh:VA.eowpy9fCvetX5g3F7ygauOyOG_a0N... \n", + " 2 {'id': 'ga4gh:VA.Co7K7Pdq72evu5C7Hr6CanDGoBZAo... \n", + " 3 {'id': 'ga4gh:VA.gz9KqF6aVsPgRcWD2UbubPGwe1LN2... \n", + " 4 {'id': 'ga4gh:VA.bQNYaiLkT_do8h6KXhLQsu9UpCFRQ... \n", + " ... ... \n", + " 1450 {'id': 'ga4gh:VA.IQ_dgFehQ9yFC80EH7IKqn3V14nEC... \n", + " 1451 {'id': 'ga4gh:VA.6wpNwv3Npnxp5vYjnCrIn_ucywJhj... \n", + " 1452 {'id': 'ga4gh:VA.d1f9HXauvNDbJdhqE6z1MzeaV4YTP... \n", + " 1453 {'id': 'ga4gh:VA.0WDJUfcKPgHhfyVJbMlc8QUCjZO6A... \n", + " 1454 {'id': 'ga4gh:VA.VhRyW9zFC8YuEiTKTu8JHyWz2VJfl... \n", + " \n", + " [1455 rows x 2 columns],\n", + " 'urn:mavedb:00000023-a-2': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.dET-JF5Ck81eYg2apI9o8lGK9FtGv... \n", + " 1 {'id': 'ga4gh:VA.bIoSGsu__QtUgVG5tG6Gvc6P0c7eS... \n", + " 2 {'id': 'ga4gh:VA.ZccYLLSrx7eraJce2Hc8Rcr-TJ0EK... \n", + " 3 {'id': 'ga4gh:VA.OfU3kMd_19j5fH7IYK3Tz9w1Ytpao... \n", + " 4 {'id': 'ga4gh:VA.taN0_XxCdl-aEHbVIl5d5QDmgFJvd... \n", + " .. ... \n", + " 949 {'id': 'ga4gh:VA.vKkR853tAymsr4zJFt9ZCaNvv8wwv... \n", + " 950 {'id': 'ga4gh:VA.CiIjXSme8dyR5nponSfCicChUmFHl... \n", + " 951 {'id': 'ga4gh:VA.Qbfu5LS06TtfyDuMMQt6jNaStuE4S... \n", + " 952 {'id': 'ga4gh:VA.3ebz7ntsD5tilTlOTy-vFnPHwn8PA... \n", + " 953 {'id': 'ga4gh:VA.6ooFNX0GC6KlhBk3eo0F7CVCgasRb... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.pTORP9NROdfSibB_aotzDhjD3tTke... \n", + " 1 {'id': 'ga4gh:VA.i-72CQpIC-hY_lHlqnEoJ8KAeiY2a... \n", + " 2 {'id': 'ga4gh:VA.guLtgmWfD7dZztOnklen6O4IPY7Gx... \n", + " 3 {'id': 'ga4gh:VA.RpkpfpjmMisxhV851YmQYyvTOMEx-... \n", + " 4 {'id': 'ga4gh:VA.AaFpTUuFwNxTO3MF1COf4h6y4u0AX... \n", + " .. ... \n", + " 949 {'id': 'ga4gh:VA.psbPEFt0lkyWDSD9-eLqkwW8GEnIa... \n", + " 950 {'id': 'ga4gh:VA.okz_A7_UT2CPCokf99B9Rb_905ZOL... \n", + " 951 {'id': 'ga4gh:VA.1i3SeouK_BVboaFecb-ekkf-ePcnT... \n", + " 952 {'id': 'ga4gh:VA.vveQbFD92OO5uWt2CLL6UoegN4YLI... \n", + " 953 {'id': 'ga4gh:VA.7xWMENEFmn58u8gwCsQuNQPcgCEKX... \n", + " \n", + " [954 rows x 2 columns],\n", + " 'urn:mavedb:00000029-a-2': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.sf20_ihYkCXOW-eVtkXXROdsP-72P... \n", + " 1 {'id': 'ga4gh:VA.hrn2rTpSbVMWu5IWhQb9b2dyiqBx8... \n", + " 2 {'id': 'ga4gh:VA.m4gw9V5ml3aKCNAde9JuYALc5UV3y... \n", + " 3 {'id': 'ga4gh:VA.u2pUTbLYRye1awCpLtEWLfpyUXIUe... \n", + " 4 {'id': 'ga4gh:VA.Jw0O-eU_zkuEoh8MpAp9H8__PxXmM... \n", + " ... ... \n", + " 1793 {'id': 'ga4gh:VA.aILVRRDZHdEGi-T_XY4e09LM0c_WQ... \n", + " 1794 {'id': 'ga4gh:VA.dwv343iTdmQSVAj6BbKaG6__-rPbK... \n", + " 1795 {'id': 'ga4gh:VA.bm65IPzMoInJX6nk6jmLHfX0fTgFa... \n", + " 1796 {'id': 'ga4gh:VA.I3KIabPCzZLY5Qz8jKku3GgkR9CMJ... \n", + " 1797 {'id': 'ga4gh:VA.wLpfah7fK2C6asbZEe--rTopz2R9S... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.JDfPubJjmK3aidfYv_l15GW6rpxd0... \n", + " 1 {'id': 'ga4gh:VA.G0AmQ1QRsEyPIvARihre7KY17TT7G... \n", + " 2 {'id': 'ga4gh:VA.kPgC5AEdhWnYYV2gdDV5dfAXFBwhp... \n", + " 3 {'id': 'ga4gh:VA.KTMqXe7bTUVTglZGzHtebdCk2X-Km... \n", + " 4 {'id': 'ga4gh:VA.kLScfwjGcZVcGCtd9bP6AnMxZ7CKK... \n", + " ... ... \n", + " 1793 {'id': 'ga4gh:VA.jqPGxeHWFoE3qSSRH3wHI-Jabntv9... \n", + " 1794 {'id': 'ga4gh:VA.oW9KA4W0eNgCDWuNF5JOHEKYlFZiT... \n", + " 1795 {'id': 'ga4gh:VA.xt6w7J54HVsjENPz2QWUsF5oROZih... \n", + " 1796 {'id': 'ga4gh:VA.qNa33a1F0UruRa8yj3uKenLyOJEim... \n", + " 1797 {'id': 'ga4gh:VA.n7gXWkkWGfAc-dj6d0qW2BbI5xM2E... \n", + " \n", + " [1798 rows x 2 columns]}" + ] + }, + "execution_count": 11, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "for key in vrs_mappings_noncoding:\n", + " dna_or_prot[key] = 'dna'\n", + "vrs_mappings_noncoding" + ] + }, + { + "cell_type": "code", + "execution_count": 12, + "id": "842ad3bb", + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "{'urn:mavedb:00000041-a-1': 'protein',\n", + " 'urn:mavedb:00000048-a-1': 'protein',\n", + " 'urn:mavedb:00000068-b-1': 'protein',\n", + " 'urn:mavedb:00000045-c-1': 'protein',\n", + " 'urn:mavedb:00000099-a-1': 'dna',\n", + " 'urn:mavedb:00000001-c-1': 'dna',\n", + " 'urn:mavedb:00000049-a-3': 'protein',\n", + " 'urn:mavedb:00000050-a-1': 'protein',\n", + " 'urn:mavedb:00000061-i-1': 'protein',\n", + " 'urn:mavedb:00000094-a-5': 'protein',\n", + " 'urn:mavedb:00000043-a-2': 'dna',\n", + " 'urn:mavedb:00000055-0-1': 'protein',\n", + " 'urn:mavedb:00000104-a-2': 'dna',\n", + " 'urn:mavedb:00000005-a-6': 'dna',\n", + " 'urn:mavedb:00000098-a-1': 'protein',\n", + " 'urn:mavedb:00000108-a-2': 'protein',\n", + " 'urn:mavedb:00000001-a-4': 'dna',\n", + " 'urn:mavedb:00000094-a-6': 'protein',\n", + " 'urn:mavedb:00000078-a-1': 'protein',\n", + " 'urn:mavedb:00000103-c-1': 'protein',\n", + " 'urn:mavedb:00000043-a-1': 'dna',\n", + " 'urn:mavedb:00000061-d-1': 'protein',\n", + " 'urn:mavedb:00000046-a-1': 'protein',\n", + " 'urn:mavedb:00000081-a-1': 'protein',\n", + " 'urn:mavedb:00000097-r-1': 'protein',\n", + " 'urn:mavedb:00000067-a-1': 'protein',\n", + " 'urn:mavedb:00000001-c-2': 'protein',\n", + " 'urn:mavedb:00000049-a-7': 'protein',\n", + " 'urn:mavedb:00000060-a-2': 'protein',\n", + " 'urn:mavedb:00000058-a-1': 'protein',\n", + " 'urn:mavedb:00000045-k-1': 'protein',\n", + " 'urn:mavedb:00000094-a-14': 'protein',\n", + " 'urn:mavedb:00000069-a-2': 'protein',\n", + " 'urn:mavedb:00000106-b-1': 'protein',\n", + " 'urn:mavedb:00000046-a-2': 'protein',\n", + " 'urn:mavedb:00000069-a-1': 'protein',\n", + " 'urn:mavedb:00000049-a-8': 'protein',\n", + " 'urn:mavedb:00000047-c-1': 'protein',\n", + " 'urn:mavedb:00000094-a-8': 'protein',\n", + " 'urn:mavedb:00000041-b-1': 'protein',\n", + " 'urn:mavedb:00000097-o-1': 'protein',\n", + " 'urn:mavedb:00000045-a-1': 'protein',\n", + " 'urn:mavedb:00000097-0-1': 'protein',\n", + " 'urn:mavedb:00000097-h-1': 'protein',\n", + " 'urn:mavedb:00000061-h-1': 'protein',\n", + " 'urn:mavedb:00000066-a-1': 'protein',\n", + " 'urn:mavedb:00000108-a-3': 'protein',\n", + " 'urn:mavedb:00000094-a-15': 'protein',\n", + " 'urn:mavedb:00000094-a-2': 'protein',\n", + " 'urn:mavedb:00000094-a-4': 'protein',\n", + " 'urn:mavedb:00000059-a-1': 'protein',\n", + " 'urn:mavedb:00000094-a-1': 'protein',\n", + " 'urn:mavedb:00000045-g-1': 'protein',\n", + " 'urn:mavedb:00000097-i-1': 'protein',\n", + " 'urn:mavedb:00000097-w-1': 'protein',\n", + " 'urn:mavedb:00000045-j-1': 'protein',\n", + " 'urn:mavedb:00000103-b-1': 'protein',\n", + " 'urn:mavedb:00000097-g-1': 'protein',\n", + " 'urn:mavedb:00000049-a-4': 'protein',\n", + " 'urn:mavedb:00000097-b-1': 'protein',\n", + " 'urn:mavedb:00000097-k-1': 'protein',\n", + " 'urn:mavedb:00000102-0-1': 'protein',\n", + " 'urn:mavedb:00000001-b-2': 'dna',\n", + " 'urn:mavedb:00000094-a-3': 'protein',\n", + " 'urn:mavedb:00000061-g-1': 'protein',\n", + " 'urn:mavedb:00000001-d-1': 'dna',\n", + " 'urn:mavedb:00000097-p-1': 'protein',\n", + " 'urn:mavedb:00000097-x-1': 'protein',\n", + " 'urn:mavedb:00000055-a-1': 'protein',\n", + " 'urn:mavedb:00000094-a-10': 'protein',\n", + " 'urn:mavedb:00000045-i-1': 'protein',\n", + " 'urn:mavedb:00000101-a-1': 'protein',\n", + " 'urn:mavedb:00000053-a-1': 'protein',\n", + " 'urn:mavedb:00000097-v-1': 'protein',\n", + " 'urn:mavedb:00000091-a-1': 'protein',\n", + " 'urn:mavedb:00000048-c-1': 'protein',\n", + " 'urn:mavedb:00000051-b-1': 'protein',\n", + " 'urn:mavedb:00000097-m-1': 'protein',\n", + " 'urn:mavedb:00000001-b-1': 'protein',\n", + " 'urn:mavedb:00000103-a-1': 'protein',\n", + " 'urn:mavedb:00000097-f-1': 'protein',\n", + " 'urn:mavedb:00000057-b-1': 'protein',\n", + " 'urn:mavedb:00000097-s-1': 'protein',\n", + " 'urn:mavedb:00000045-f-1': 'protein',\n", + " 'urn:mavedb:00000072-a-1': 'protein',\n", + " 'urn:mavedb:00000095-b-1': 'protein',\n", + " 'urn:mavedb:00000001-a-1': 'protein',\n", + " 'urn:mavedb:00000049-a-2': 'protein',\n", + " 'urn:mavedb:00000062-b-1': 'dna',\n", + " 'urn:mavedb:00000094-a-12': 'protein',\n", + " 'urn:mavedb:00000057-c-1': 'protein',\n", + " 'urn:mavedb:00000094-a-7': 'protein',\n", + " 'urn:mavedb:00000061-f-1': 'protein',\n", + " 'urn:mavedb:00000001-a-2': 'dna',\n", + " 'urn:mavedb:00000003-b-2': 'protein',\n", + " 'urn:mavedb:00000062-a-1': 'dna',\n", + " 'urn:mavedb:00000097-e-1': 'protein',\n", + " 'urn:mavedb:00000005-a-5': 'dna',\n", + " 'urn:mavedb:00000057-d-1': 'protein',\n", + " 'urn:mavedb:00000068-a-1': 'protein',\n", + " 'urn:mavedb:00000049-a-6': 'protein',\n", + " 'urn:mavedb:00000104-a-1': 'dna',\n", + " 'urn:mavedb:00000049-a-1': 'protein',\n", + " 'urn:mavedb:00000013-b-1': 'protein',\n", + " 'urn:mavedb:00000093-a-1': 'dna',\n", + " 'urn:mavedb:00000001-a-3': 'dna',\n", + " 'urn:mavedb:00000045-d-1': 'protein',\n", + " 'urn:mavedb:00000108-a-1': 'protein',\n", + " 'urn:mavedb:00000096-a-1': 'protein',\n", + " 'urn:mavedb:00000003-a-2': 'protein',\n", + " 'urn:mavedb:00000097-c-1': 'protein',\n", + " 'urn:mavedb:00000106-a-1': 'protein',\n", + " 'urn:mavedb:00000036-a-2': 'protein',\n", + " 'urn:mavedb:00000097-t-1': 'protein',\n", + " 'urn:mavedb:00000097-l-1': 'protein',\n", + " 'urn:mavedb:00000094-a-11': 'protein',\n", + " 'urn:mavedb:00000002-a-2': 'protein',\n", + " 'urn:mavedb:00000061-c-1': 'protein',\n", + " 'urn:mavedb:00000035-a-2': 'protein',\n", + " 'urn:mavedb:00000035-a-3': 'protein',\n", + " 'urn:mavedb:00000094-a-13': 'protein',\n", + " 'urn:mavedb:00000045-h-1': 'protein',\n", + " 'urn:mavedb:00000051-c-1': 'protein',\n", + " 'urn:mavedb:00000097-u-1': 'protein',\n", + " 'urn:mavedb:00000097-d-1': 'protein',\n", + " 'urn:mavedb:00000036-a-1': 'protein',\n", + " 'urn:mavedb:00000105-a-1': 'protein',\n", + " 'urn:mavedb:00000081-a-2': 'protein',\n", + " 'urn:mavedb:00000053-a-2': 'protein',\n", + " 'urn:mavedb:00000060-a-1': 'protein',\n", + " 'urn:mavedb:00000013-a-1': 'protein',\n", + " 'urn:mavedb:00000097-z-1': 'protein',\n", + " 'urn:mavedb:00000094-a-9': 'protein',\n", + " 'urn:mavedb:00000045-e-1': 'protein',\n", + " 'urn:mavedb:00000097-j-1': 'protein',\n", + " 'urn:mavedb:00000047-b-1': 'protein',\n", + " 'urn:mavedb:00000003-b-1': 'dna',\n", + " 'urn:mavedb:00000054-a-1': 'dna',\n", + " 'urn:mavedb:00000061-a-1': 'protein',\n", + " 'urn:mavedb:00000047-a-1': 'protein',\n", + " 'urn:mavedb:00000035-a-1': 'protein',\n", + " 'urn:mavedb:00000078-b-1': 'protein',\n", + " 'urn:mavedb:00000045-l-1': 'protein',\n", + " 'urn:mavedb:00000065-a-1': 'protein',\n", + " 'urn:mavedb:00000046-a-3': 'protein',\n", + " 'urn:mavedb:00000068-c-1': 'protein',\n", + " 'urn:mavedb:00000005-a-2': 'protein',\n", + " 'urn:mavedb:00000061-e-1': 'protein',\n", + " 'urn:mavedb:00000055-b-1': 'protein',\n", + " 'urn:mavedb:00000057-a-1': 'protein',\n", + " 'urn:mavedb:00000097-n-1': 'protein',\n", + " 'urn:mavedb:00000001-d-2': 'protein',\n", + " 'urn:mavedb:00000005-a-3': 'protein',\n", + " 'urn:mavedb:00000106-c-1': 'protein',\n", + " 'urn:mavedb:00000045-b-1': 'protein',\n", + " 'urn:mavedb:00000048-b-1': 'protein',\n", + " 'urn:mavedb:00000095-a-1': 'protein',\n", + " 'urn:mavedb:00000049-a-5': 'protein',\n", + " 'urn:mavedb:00000097-y-1': 'protein',\n", + " 'urn:mavedb:00000005-a-1': 'protein',\n", + " 'urn:mavedb:00000097-a-1': 'protein',\n", + " 'urn:mavedb:00000003-a-1': 'dna',\n", + " 'urn:mavedb:00000005-a-4': 'protein',\n", + " 'urn:mavedb:00000002-a-1': 'dna',\n", + " 'urn:mavedb:00000107-a-1': 'protein',\n", + " 'urn:mavedb:00000103-d-1': 'protein',\n", + " 'urn:mavedb:00000061-b-1': 'protein',\n", + " 'urn:mavedb:00000097-q-1': 'protein',\n", + " 'urn:mavedb:00000018-a-1': 'dna',\n", + " 'urn:mavedb:00000083-b-1': 'dna',\n", + " 'urn:mavedb:00000083-h-1': 'dna',\n", + " 'urn:mavedb:00000034-b-1': 'dna',\n", + " 'urn:mavedb:00000021-a-1': 'dna',\n", + " 'urn:mavedb:00000031-a-1': 'dna',\n", + " 'urn:mavedb:00000083-i-1': 'dna',\n", + " 'urn:mavedb:00000026-a-1': 'dna',\n", + " 'urn:mavedb:00000083-j-1': 'dna',\n", + " 'urn:mavedb:00000083-e-1': 'dna',\n", + " 'urn:mavedb:00000014-a-1': 'dna',\n", + " 'urn:mavedb:00000032-a-1': 'dna',\n", + " 'urn:mavedb:00000031-c-1': 'dna',\n", + " 'urn:mavedb:00000083-a-1': 'dna',\n", + " 'urn:mavedb:00000024-a-1': 'dna',\n", + " 'urn:mavedb:00000023-a-1': 'dna',\n", + " 'urn:mavedb:00000083-d-1': 'dna',\n", + " 'urn:mavedb:00000027-a-1': 'dna',\n", + " 'urn:mavedb:00000033-a-1': 'dna',\n", + " 'urn:mavedb:00000083-c-1': 'dna',\n", + " 'urn:mavedb:00000028-a-1': 'dna',\n", + " 'urn:mavedb:00000029-a-1': 'dna',\n", + " 'urn:mavedb:00000083-g-1': 'dna',\n", + " 'urn:mavedb:00000027-b-1': 'dna',\n", + " 'urn:mavedb:00000031-b-1': 'dna',\n", + " 'urn:mavedb:00000006-a-1': 'dna',\n", + " 'urn:mavedb:00000022-a-1': 'dna',\n", + " 'urn:mavedb:00000015-a-1': 'dna',\n", + " 'urn:mavedb:00000025-a-1': 'dna',\n", + " 'urn:mavedb:00000019-a-1': 'dna',\n", + " 'urn:mavedb:00000017-a-1': 'dna',\n", + " 'urn:mavedb:00000083-f-1': 'dna',\n", + " 'urn:mavedb:00000031-d-1': 'dna',\n", + " 'urn:mavedb:00000020-a-1': 'dna',\n", + " 'urn:mavedb:00000007-a-1': 'dna',\n", + " 'urn:mavedb:00000016-a-1': 'dna',\n", + " 'urn:mavedb:00000029-b-1': 'dna',\n", + " 'urn:mavedb:00000030-a-1': 'dna',\n", + " 'urn:mavedb:00000034-a-1': 'dna',\n", + " 'urn:mavedb:00000023-a-2': 'dna',\n", + " 'urn:mavedb:00000029-a-2': 'dna'}" + ] + }, + "execution_count": 12, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "dna_or_prot" + ] + }, + { + "cell_type": "code", + "execution_count": 13, + "id": "6136c2c1", + "metadata": {}, + "outputs": [], + "source": [ + "def rep_mapping(pre_mapped, post_mapped, score):\n", + " obj = {}\n", + " obj['pre_mapped'] = pre_mapped\n", + " obj['post_mapped'] = post_mapped\n", + " obj['relation'] = 'SO:is_homologous_to'\n", + " obj['score'] = float(score)\n", + " if isnan(float(obj['score'])):\n", + " obj['score'] = None\n", + " return obj" + ] + }, + { + "cell_type": "code", + "execution_count": 14, + "id": "577fc3a7", + "metadata": {}, + "outputs": [], + "source": [ + "def get_allele(vrs_dict):\n", + " obj = {}\n", + " obj['type'] = 'SequenceInterval'\n", + " obj['start'] = vrs_dict['location']['start']\n", + " obj['end'] = vrs_dict['location']['end']\n", + " vrs_dict['location']['interval'] = obj\n", + " del vrs_dict['location']['start']\n", + " del vrs_dict['location']['end']\n", + " return Allele(**vrs_dict)" + ] + }, + { + "cell_type": "code", + "execution_count": 15, + "id": "991bb3f7", + "metadata": {}, + "outputs": [], + "source": [ + "var_mappings = {}\n", + "\n", + "for key in vrs_mappings_coding:\n", + " if key in mappings_dict.keys():\n", + " curr = vrs_mappings_coding[key]\n", + " if dna_or_prot[key] == 'protein':\n", + " scores = scores_coding[key][0]\n", + " else:\n", + " scores = scores_coding[key][1]\n", + " mappings = []\n", + " for i in range(len(curr.index)):\n", + " obj = rep_mapping(curr.at[i, 'pre_mapping'], curr.at[i, 'mapped'], scores[i])\n", + " mappings.append(obj)\n", + " var_mappings[key] = mappings" + ] + }, + { + "cell_type": "code", + "execution_count": 16, + "id": "79d1066a", + "metadata": {}, + "outputs": [], + "source": [ + "for key in vrs_mappings_noncoding:\n", + " curr = vrs_mappings_noncoding[key]\n", + " scores = scores_noncoding[key]\n", + " mappings = []\n", + " for i in range(len(curr.index)):\n", + " obj = rep_mapping(curr.at[i, 'pre_mapping'], curr.at[i, 'mapped'], scores[i])\n", + " mappings.append(obj)\n", + " var_mappings[key] = mappings" + ] + }, + { + "cell_type": "code", + "execution_count": 17, + "id": "9eb300ff", + "metadata": {}, + "outputs": [], + "source": [ + "def get_computed_reference_seq(urn):\n", + " d = {}\n", + " df = mave_dat[mave_dat['urn'] == urn]\n", + " seq = df['target_sequence'].values[0]\n", + " seq = Seq(seq)\n", + " \n", + " if dna_or_prot[urn] == 'protein':\n", + " if len(set(seq)) > 4:\n", + " d['sequence'] = str(seq)\n", + " else:\n", + " d['sequence'] = str(seq.translate(table=1)).replace('*', '')\n", + " else:\n", + " d['sequence'] = str(seq)\n", + " d['sequence_type'] = dna_or_prot[urn]\n", + " d['sequence_id'] = 'ga4gh:SQ.' + sha512t24u(d['sequence'].encode('ascii'))\n", + " return d" + ] + }, + { + "cell_type": "code", + "execution_count": 18, + "id": "a40ab609", + "metadata": {}, + "outputs": [], + "source": [ + "def get_refseq(dp, ref):\n", + " aliases = dp.get_metadata(ref)['aliases']\n", + " f = filter(lambda x: 'refseq' in x, aliases)\n", + " return list(f)[0].split(':')[1]\n", + "\n", + "def get_human_reference_seq(dp, urn):\n", + " curr = var_mappings[urn]\n", + " try:\n", + " temp = curr[0]['post_mapped']['location']['sequence_id']\n", + " except:\n", + " temp = curr[0]['post_mapped']['members'][0]['location']['sequence_id']\n", + " d = {}\n", + " d['sequence_type'] = dna_or_prot[urn]\n", + " d['sequence_id'] = temp\n", + " d['sequence_accessions'] = [get_refseq(dp, temp)]\n", + " return d" + ] + }, + { + "cell_type": "code", + "execution_count": 19, + "id": "18a13903", + "metadata": {}, + "outputs": [], + "source": [ + "def get_ref_state(allele, seq, typ, strand, acc, status):\n", + " start = allele['location']['start']['value']\n", + " end = allele['location']['end']['value']\n", + " d = {}\n", + " d['type'] = 'LiteralSequenceExpression'\n", + " \n", + " if status == 'pre_mapped' or strand != -1:\n", + " try:\n", + " d['sequence'] = seq[start:end]\n", + " except:\n", + " try:\n", + " d[sequence] = seq[start-1:end-1]\n", + " except: \n", + " d['sequence'] = '' \n", + " else:\n", + " temp = Seq(str(sr[acc][start:end]))\n", + " d['sequence'] = str(temp)\n", + " \n", + " return d" + ] + }, + { + "cell_type": "code", + "execution_count": 20, + "id": "bc08a3e7", + "metadata": {}, + "outputs": [], + "source": [ + "from Bio.SeqUtils import seq3\n", + "def get_protein_hgvs(a, ac):\n", + " if ac.startswith('NP'):\n", + " stype = 'p'\n", + " else:\n", + " stype = 'g'\n", + " start = a.location.interval.start.value\n", + " end = a.location.interval.end.value\n", + "\n", + " if start == end: \n", + " ref = None\n", + " aas = dp.get_sequence(ac, start-1, start)\n", + " aae = dp.get_sequence(ac, end, end + 1)\n", + " end += 1\n", + " else:\n", + " ref = dp.get_sequence(ac, start, end)\n", + " aas = dp.get_sequence(ac, start, start + 1)\n", + " aae = dp.get_sequence(ac, end - 1, end)\n", + " start += 1\n", + "\n", + " if stype == 'p':\n", + " ival = hgvs.location.Interval(start=hgvs.location.AAPosition(base=start, aa = aas), end=hgvs.location.AAPosition(base=end, aa = aae))\n", + " else:\n", + " ival = hgvs.location.Interval(start=hgvs.location.SimplePosition(base=start), end=hgvs.location.SimplePosition(base=end))\n", + " alt = a.state.sequence\n", + "\n", + " edit = '' # Set default\n", + " if alt == ref:\n", + " edit = '='\n", + " if ref != None:\n", + " if 2*ref == alt or len(ref) == 1 and set(ref) == set(alt):\n", + " edit = 'dup'\n", + " if alt == '':\n", + " edit = 'del'\n", + " \n", + " if edit != 'dup' or edit != 'del' or edit != '=':\n", + " if stype == 'p':\n", + " edit = hgvs.edit.AARefAlt(ref=ref, alt=alt)\n", + " else:\n", + " edit = hgvs.edit.NARefAlt(ref=ref, alt=alt)\n", + " \n", + " if alt != ref:\n", + " posedit = hgvs.posedit.PosEdit(pos=ival, edit=edit)\n", + " else:\n", + " posedit = seq3(ref) + str(start) + '='\n", + "\n", + " var = str(hgvs.sequencevariant.SequenceVariant(ac=ac,type=stype,posedit=posedit))\n", + " if var.endswith('delins') == True:\n", + " var = var.replace('delins', 'del')\n", + " return var" + ] + }, + { + "cell_type": "code", + "execution_count": 21, + "id": "972d7e78", + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "urn:mavedb:00000041-a-1\n", + "urn:mavedb:00000048-a-1\n", + "urn:mavedb:00000068-b-1\n", + "urn:mavedb:00000045-c-1\n", + "urn:mavedb:00000099-a-1\n", + "urn:mavedb:00000001-c-1\n", + "urn:mavedb:00000049-a-3\n", + "urn:mavedb:00000050-a-1\n", + "urn:mavedb:00000061-i-1\n", + "urn:mavedb:00000094-a-5\n", + "urn:mavedb:00000043-a-2\n", + "urn:mavedb:00000055-0-1\n", + "urn:mavedb:00000104-a-2\n", + "urn:mavedb:00000005-a-6\n", + "urn:mavedb:00000098-a-1\n", + "urn:mavedb:00000108-a-2\n", + "urn:mavedb:00000001-a-4\n", + "urn:mavedb:00000094-a-6\n", + "urn:mavedb:00000078-a-1\n", + "urn:mavedb:00000103-c-1\n", + "urn:mavedb:00000043-a-1\n", + "urn:mavedb:00000061-d-1\n", + "urn:mavedb:00000046-a-1\n", + "urn:mavedb:00000081-a-1\n", + "urn:mavedb:00000097-r-1\n", + "urn:mavedb:00000067-a-1\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "urn:mavedb:00000001-c-2\n", + "urn:mavedb:00000049-a-7\n", + "urn:mavedb:00000060-a-2\n", + "urn:mavedb:00000058-a-1\n", + "urn:mavedb:00000045-k-1\n", + "urn:mavedb:00000094-a-14\n", + "urn:mavedb:00000069-a-2\n", + "urn:mavedb:00000106-b-1\n", + "urn:mavedb:00000046-a-2\n", + "urn:mavedb:00000069-a-1\n", + "urn:mavedb:00000049-a-8\n", + "urn:mavedb:00000047-c-1\n", + "urn:mavedb:00000094-a-8\n", + "urn:mavedb:00000041-b-1\n", + "urn:mavedb:00000097-o-1\n", + "urn:mavedb:00000045-a-1\n", + "urn:mavedb:00000097-0-1\n", + "urn:mavedb:00000097-h-1\n", + "urn:mavedb:00000061-h-1\n", + "urn:mavedb:00000066-a-1\n", + "urn:mavedb:00000108-a-3\n", + "urn:mavedb:00000094-a-15\n", + "urn:mavedb:00000094-a-2\n", + "urn:mavedb:00000094-a-4\n", + "urn:mavedb:00000059-a-1\n", + "urn:mavedb:00000094-a-1\n", + "urn:mavedb:00000045-g-1\n", + "urn:mavedb:00000097-i-1\n", + "urn:mavedb:00000097-w-1\n", + "urn:mavedb:00000045-j-1\n", + "urn:mavedb:00000103-b-1\n", + "urn:mavedb:00000097-g-1\n", + "urn:mavedb:00000049-a-4\n", + "urn:mavedb:00000097-b-1\n", + "urn:mavedb:00000097-k-1\n", + "urn:mavedb:00000102-0-1\n", + "urn:mavedb:00000001-b-2\n", + "urn:mavedb:00000094-a-3\n", + "urn:mavedb:00000061-g-1\n", + "urn:mavedb:00000001-d-1\n", + "urn:mavedb:00000097-p-1\n", + "urn:mavedb:00000097-x-1\n", + "urn:mavedb:00000055-a-1\n", + "urn:mavedb:00000094-a-10\n", + "urn:mavedb:00000045-i-1\n", + "urn:mavedb:00000101-a-1\n", + "urn:mavedb:00000053-a-1\n", + "urn:mavedb:00000097-v-1\n", + "urn:mavedb:00000091-a-1\n", + "urn:mavedb:00000048-c-1\n", + "urn:mavedb:00000051-b-1\n", + "urn:mavedb:00000097-m-1\n", + "urn:mavedb:00000001-b-1\n", + "urn:mavedb:00000103-a-1\n", + "urn:mavedb:00000097-f-1\n", + "urn:mavedb:00000057-b-1\n", + "urn:mavedb:00000097-s-1\n", + "urn:mavedb:00000045-f-1\n", + "urn:mavedb:00000072-a-1\n", + "urn:mavedb:00000095-b-1\n", + "urn:mavedb:00000001-a-1\n", + "urn:mavedb:00000049-a-2\n", + "urn:mavedb:00000062-b-1\n", + "urn:mavedb:00000094-a-12\n", + "urn:mavedb:00000057-c-1\n", + "urn:mavedb:00000094-a-7\n", + "urn:mavedb:00000061-f-1\n", + "urn:mavedb:00000001-a-2\n", + "urn:mavedb:00000003-b-2\n", + "urn:mavedb:00000062-a-1\n", + "urn:mavedb:00000097-e-1\n", + "urn:mavedb:00000005-a-5\n", + "urn:mavedb:00000057-d-1\n", + "urn:mavedb:00000068-a-1\n", + "urn:mavedb:00000049-a-6\n", + "urn:mavedb:00000104-a-1\n", + "urn:mavedb:00000049-a-1\n", + "urn:mavedb:00000013-b-1\n", + "urn:mavedb:00000093-a-1\n", + "urn:mavedb:00000001-a-3\n", + "urn:mavedb:00000045-d-1\n", + "urn:mavedb:00000108-a-1\n", + "urn:mavedb:00000096-a-1\n", + "urn:mavedb:00000003-a-2\n", + "urn:mavedb:00000097-c-1\n", + "urn:mavedb:00000106-a-1\n", + "urn:mavedb:00000036-a-2\n", + "urn:mavedb:00000097-t-1\n", + "urn:mavedb:00000097-l-1\n", + "urn:mavedb:00000094-a-11\n", + "urn:mavedb:00000002-a-2\n", + "urn:mavedb:00000061-c-1\n", + "urn:mavedb:00000035-a-2\n", + "urn:mavedb:00000035-a-3\n", + "urn:mavedb:00000094-a-13\n", + "urn:mavedb:00000045-h-1\n", + "urn:mavedb:00000051-c-1\n", + "urn:mavedb:00000097-u-1\n", + "urn:mavedb:00000097-d-1\n", + "urn:mavedb:00000036-a-1\n", + "urn:mavedb:00000081-a-2\n", + "urn:mavedb:00000053-a-2\n", + "urn:mavedb:00000060-a-1\n", + "urn:mavedb:00000013-a-1\n", + "urn:mavedb:00000097-z-1\n", + "urn:mavedb:00000094-a-9\n", + "urn:mavedb:00000045-e-1\n", + "urn:mavedb:00000097-j-1\n", + "urn:mavedb:00000047-b-1\n", + "urn:mavedb:00000003-b-1\n", + "urn:mavedb:00000054-a-1\n", + "urn:mavedb:00000061-a-1\n", + "urn:mavedb:00000047-a-1\n", + "urn:mavedb:00000035-a-1\n", + "urn:mavedb:00000078-b-1\n", + "urn:mavedb:00000045-l-1\n", + "urn:mavedb:00000065-a-1\n", + "urn:mavedb:00000046-a-3\n", + "urn:mavedb:00000068-c-1\n", + "urn:mavedb:00000005-a-2\n", + "urn:mavedb:00000061-e-1\n", + "urn:mavedb:00000055-b-1\n", + "urn:mavedb:00000057-a-1\n", + "urn:mavedb:00000097-n-1\n", + "urn:mavedb:00000001-d-2\n", + "urn:mavedb:00000005-a-3\n", + "urn:mavedb:00000106-c-1\n", + "urn:mavedb:00000045-b-1\n", + "urn:mavedb:00000048-b-1\n", + "urn:mavedb:00000095-a-1\n", + "urn:mavedb:00000049-a-5\n", + "urn:mavedb:00000097-y-1\n", + "urn:mavedb:00000005-a-1\n", + "urn:mavedb:00000097-a-1\n", + "urn:mavedb:00000003-a-1\n", + "urn:mavedb:00000005-a-4\n", + "urn:mavedb:00000002-a-1\n", + "urn:mavedb:00000107-a-1\n", + "urn:mavedb:00000103-d-1\n", + "urn:mavedb:00000061-b-1\n", + "urn:mavedb:00000097-q-1\n", + "urn:mavedb:00000018-a-1\n", + "urn:mavedb:00000083-b-1\n", + "urn:mavedb:00000083-h-1\n", + "urn:mavedb:00000034-b-1\n", + "urn:mavedb:00000021-a-1\n", + "urn:mavedb:00000031-a-1\n", + "urn:mavedb:00000083-i-1\n", + "urn:mavedb:00000026-a-1\n", + "urn:mavedb:00000083-j-1\n", + "urn:mavedb:00000083-e-1\n", + "urn:mavedb:00000014-a-1\n", + "urn:mavedb:00000032-a-1\n", + "urn:mavedb:00000031-c-1\n", + "urn:mavedb:00000083-a-1\n", + "urn:mavedb:00000024-a-1\n", + "urn:mavedb:00000023-a-1\n", + "urn:mavedb:00000083-d-1\n", + "urn:mavedb:00000027-a-1\n", + "urn:mavedb:00000033-a-1\n", + "urn:mavedb:00000083-c-1\n", + "urn:mavedb:00000028-a-1\n", + "urn:mavedb:00000029-a-1\n", + "urn:mavedb:00000083-g-1\n", + "urn:mavedb:00000027-b-1\n", + "urn:mavedb:00000031-b-1\n", + "urn:mavedb:00000006-a-1\n", + "urn:mavedb:00000022-a-1\n", + "urn:mavedb:00000015-a-1\n", + "urn:mavedb:00000025-a-1\n", + "urn:mavedb:00000019-a-1\n", + "urn:mavedb:00000017-a-1\n", + "urn:mavedb:00000083-f-1\n", + "urn:mavedb:00000031-d-1\n", + "urn:mavedb:00000020-a-1\n", + "urn:mavedb:00000007-a-1\n", + "urn:mavedb:00000016-a-1\n", + "urn:mavedb:00000029-b-1\n", + "urn:mavedb:00000030-a-1\n", + "urn:mavedb:00000034-a-1\n", + "urn:mavedb:00000023-a-2\n", + "urn:mavedb:00000029-a-2\n" + ] + } + ], + "source": [ + "import json\n", + "response = requests.get('https://www.mavedb.org/api/scoresets/')\n", + "json_parse = response.json()\n", + "dp = SeqRepoDataProxy(sr = sr)\n", + "hp = hgvs.parser.Parser()\n", + "err_urns = ['urn:mavedb:00000048-a-1', 'urn:mavedb:00000060-a-2', 'urn:mavedb:00000058-a-1', 'urn:mavedb:00000047-c-1', 'urn:mavedb:00000053-a-1', 'urn:mavedb:00000048-c-1', 'urn:mavedb:00000053-a-2', 'urn:mavedb:00000060-a-1', 'urn:mavedb:00000047-b-1', 'urn:mavedb:00000047-a-1', 'urn:mavedb:00000048-b-1']\n", + " \n", + "for key in var_mappings:\n", + " print(key)\n", + " for i in range(len(json_parse)):\n", + " if json_parse[i]['urn'] == key:\n", + " curr = json_parse[i]\n", + " continue\n", + " curr['target']['computed_reference_sequence'] = get_computed_reference_seq(key)\n", + " \n", + " if key != 'urn:mavedb:00000072-a-1': # No RefSeq\n", + " curr['mapped_reference_sequence'] = get_human_reference_seq(dp, key)\n", + " curr['mapped_scores'] = var_mappings[key]\n", + " \n", + " typ = curr['mapped_reference_sequence']['sequence_type']\n", + " strand = mave_blat[key]['strand']\n", + " acc = curr['mapped_reference_sequence']['sequence_accessions'][0]\n", + " \n", + " for i in range(len(curr['mapped_scores'])):\n", + " if 'members' not in curr['mapped_scores'][i]['pre_mapped'].keys():\n", + " pre = curr['mapped_scores'][i]['pre_mapped'] \n", + " post = curr['mapped_scores'][i]['post_mapped']\n", + " \n", + " start = curr['mapped_scores'][i]['post_mapped']['location']['start']['value']\n", + " end = curr['mapped_scores'][i]['post_mapped']['location']['end']['value']\n", + " \n", + " if key in err_urns or '97-' in key: # discordance/already mapped\n", + " ref_allele = str(sr[acc][start:end])\n", + " vod_pre = VariationDescriptor(id = pre['id'], variation = get_allele(pre), vrs_ref_allele_seq = ref_allele).dict()\n", + " post = get_allele(post)\n", + " if acc.startswith('NP'):\n", + " vod_post = VariationDescriptor(id = post.id, variation = post, expressions = [Expression(syntax='hgvs.p', value = get_protein_hgvs(post, acc))],vrs_ref_allele_seq = ref_allele).dict()\n", + " else:\n", + " vod_post = VariationDescriptor(id = post.id, variation = post, expressions = [Expression(syntax='hgvs.g', value = get_protein_hgvs(post, acc))],vrs_ref_allele_seq = ref_allele).dict() \n", + " vod_pre = {key:value for key, value in vod_pre.items() if value is not None}\n", + " vod_post = {key:value for key, value in vod_post.items() if value is not None}\n", + " curr['mapped_scores'][i]['pre_mapped'] = vod_pre\n", + " curr['mapped_scores'][i]['post_mapped'] = vod_post\n", + " \n", + " else:\n", + " ref_allele = get_ref_state(pre, curr['target']['computed_reference_sequence']['sequence'] ,typ, strand, acc, 'pre_mapped')['sequence']\n", + " vod_pre = VariationDescriptor(id = pre['id'], variation = get_allele(pre), vrs_ref_allele_seq = ref_allele).dict()\n", + " if typ == 'dna' and strand != 1:\n", + " ref_allele = get_ref_state(post, curr['target']['computed_reference_sequence']['sequence'] ,typ, strand, acc, 'post_mapped')['sequence']\n", + " post = get_allele(post)\n", + " if acc.startswith('NP'):\n", + " vod_post = VariationDescriptor(id = post.id, variation = post, expressions = [Expression(syntax='hgvs.p', value = get_protein_hgvs(post, acc))],vrs_ref_allele_seq = ref_allele).dict()\n", + " else:\n", + " vod_post = VariationDescriptor(id = post.id, variation = post, expressions = [Expression(syntax='hgvs.g', value = get_protein_hgvs(post, acc))],vrs_ref_allele_seq = ref_allele).dict() \n", + " vod_pre = {key:value for key, value in vod_pre.items() if value is not None}\n", + " vod_post = {key:value for key, value in vod_post.items() if value is not None}\n", + " curr['mapped_scores'][i]['pre_mapped'] = vod_pre\n", + " curr['mapped_scores'][i]['post_mapped'] = vod_post\n", + " \n", + " else:\n", + " for j in range(len(curr['mapped_scores'][i]['pre_mapped']['members'])):\n", + " pre = curr['mapped_scores'][i]['pre_mapped']['members'][j]\n", + " post = curr['mapped_scores'][i]['post_mapped']['members'][j]\n", + " \n", + " start = curr['mapped_scores'][i]['post_mapped']['members'][j]['location']['start']['value']\n", + " end = curr['mapped_scores'][i]['post_mapped']['members'][j]['location']['end']['value']\n", + " \n", + " if key in err_urns or '97-' in key: # discordance/already mapped\n", + " ref_allele = str(sr[acc][start:end])\n", + " vod_pre = VariationDescriptor(id = pre['id'], variation = get_allele(pre), vrs_ref_allele_seq = ref_allele).dict()\n", + " post = get_allele(post)\n", + " if acc.startswith('NP'):\n", + " vod_post = VariationDescriptor(id = post.id, variation = post, expressions = [Expression(syntax='hgvs.p', value = get_protein_hgvs(post, acc))],vrs_ref_allele_seq = ref_allele).dict()\n", + " else:\n", + " vod_post = VariationDescriptor(id = post.id, variation = post, expressions = [Expression(syntax='hgvs.g', value = get_protein_hgvs(post, acc))],vrs_ref_allele_seq = ref_allele).dict() \n", + " vod_pre = {key:value for key, value in vod_pre.items() if value is not None}\n", + " vod_post = {key:value for key, value in vod_post.items() if value is not None}\n", + " curr['mapped_scores'][i]['pre_mapped']['members'][j] = vod_pre\n", + " curr['mapped_scores'][i]['post_mapped']['members'][j] = vod_post\n", + " \n", + " else:\n", + " ref_allele = get_ref_state(pre, curr['target']['computed_reference_sequence']['sequence'], typ, strand, acc, 'pre_mapped')['sequence']\n", + " vod_pre = VariationDescriptor(id = pre['id'], variation = get_allele(pre), vrs_ref_allele_seq = ref_allele).dict()\n", + " if typ == 'dna' and strand != 1:\n", + " ref_allele = get_ref_state(post, curr['target']['computed_reference_sequence']['sequence'] ,typ, strand, acc, 'post_mapped')['sequence']\n", + " post = get_allele(post)\n", + " if acc.startswith('NP'):\n", + " vod_post = VariationDescriptor(id = post.id, variation = post, expressions = [Expression(syntax='hgvs.p', value = get_protein_hgvs(post, acc))],vrs_ref_allele_seq = ref_allele).dict()\n", + " else:\n", + " vod_post = VariationDescriptor(id = post.id, variation = post, expressions = [Expression(syntax='hgvs.g', value = get_protein_hgvs(post, acc))],vrs_ref_allele_seq = ref_allele).dict() \n", + " vod_pre = {key:value for key, value in vod_pre.items() if value is not None}\n", + " vod_post = {key:value for key, value in vod_post.items() if value is not None}\n", + " curr['mapped_scores'][i]['pre_mapped']['members'][j] = vod_pre\n", + " curr['mapped_scores'][i]['post_mapped']['members'][j] = vod_post\n", + "\n", + " \n", + " urn = key.replace('urn:mavedb:', '')\n", + " with open(f'mappings/{urn}.json', 'w') as f:\n", + " json.dump(curr, f, indent = 4)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "cdc05c13", + "metadata": {}, + "outputs": [], + "source": [] + } + ], + "metadata": { + "kernelspec": { + "display_name": "mavedb-mapping", + "language": "python", + "name": "mavedb-mapping" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.10.3" + } + }, + "nbformat": 4, + "nbformat_minor": 5 +} diff --git a/notebooks/analysis/mavedb_mapping.ipynb b/notebooks/analysis/mavedb_mapping.ipynb index bdbc067..16f273d 100644 --- a/notebooks/analysis/mavedb_mapping.ipynb +++ b/notebooks/analysis/mavedb_mapping.ipynb @@ -11,17 +11,15 @@ { "cell_type": "code", "execution_count": 1, - "id": "d23864a1", + "id": "f9dce63c", "metadata": {}, "outputs": [ { "name": "stderr", "output_type": "stream", "text": [ - "Removing allOf attribute from AbsoluteCopyNumber to avoid python-jsonschema-objects error.\n", - "Removing allOf attribute from SequenceInterval to avoid python-jsonschema-objects error.\n", "Removing allOf attribute from RepeatedSequenceExpression to avoid python-jsonschema-objects error.\n", - "/Users/rsjxa001/.local/share/virtualenvs/dcd_mapping-l1Mz4xFf/lib/python3.8/site-packages/python_jsonschema_objects/__init__.py:49: UserWarning: Schema version http://json-schema.org/draft-07/schema not recognized. Some keywords and features may not be supported.\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/python_jsonschema_objects/__init__.py:49: UserWarning: Schema version http://json-schema.org/draft-07/schema not recognized. Some keywords and features may not be supported.\n", " warnings.warn(\n" ] } @@ -37,24 +35,34 @@ "from ga4gh.core import ga4gh_identify, ga4gh_serialize, ga4gh_digest, ga4gh_deref, sha512t24u\n", "from ga4gh.vrs.extras.translator import Translator\n", "from ga4gh.vrs.dataproxy import SeqRepoDataProxy\n", + "from ga4gh.vrs.normalize import normalize\n", "import pandas as pd\n", "from gene.query import QueryHandler\n", "import nest_asyncio\n", "import asyncio\n", - "from uta_tools.uta_tools import UTATools\n", - "from uta_tools.data_sources.uta_database import UTADatabase\n", - "from uta_tools.data_sources.mane_transcript_mappings import MANETranscriptMappings\n", + "from cool_seq_tool.cool_seq_tool import CoolSeqTool\n", + "from cool_seq_tool.data_sources.uta_database import UTADatabase\n", + "from cool_seq_tool.data_sources.mane_transcript_mappings import MANETranscriptMappings\n", "import pickle\n", "from os import environ\n", + "import Bio\n", "from Bio.SeqUtils import seq1\n", "from Bio.Seq import Seq\n", "from biocommons.seqrepo import SeqRepo\n", "from bs4 import BeautifulSoup\n", - "sr = SeqRepo(\"/usr/local/share/seqrepo/latest\")\n", + "sr = SeqRepo(\"/usr/local/share/seqrepo/latest\", writeable = True)\n", "environ[\"UTA_DB_URL\"] = 'postgresql://uta_admin:uta@localhost:5432/uta/uta_20210129'\n", "from pyliftover import LiftOver" ] }, + { + "cell_type": "markdown", + "id": "ba98fdd2", + "metadata": {}, + "source": [ + "# The blocks below can be run to reproduce the output in the results directory" + ] + }, { "cell_type": "markdown", "id": "a6d05229", @@ -66,7 +74,7 @@ { "cell_type": "code", "execution_count": 2, - "id": "41488d9a", + "id": "1d5cb631", "metadata": {}, "outputs": [], "source": [ @@ -277,16 +285,6 @@ " \n", " \n", " 3\n", - " urn:mavedb:00000023-a-1\n", - " AGCTCTTCACCGGAGACCCAAATACAACAAATCAAGTCGCCTGCCC...\n", - " dna\n", - " LDLR promoter\n", - " GCF_000001405.26\n", - " None\n", - " Regulatory\n", - " \n", - " \n", - " 4\n", " urn:mavedb:00000045-c-1\n", " ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTG...\n", " dna\n", @@ -296,6 +294,16 @@ " Protein coding\n", " \n", " \n", + " 4\n", + " urn:mavedb:00000018-a-1\n", + " GGTGTCTGTTTGAGGTTGCTAGTGAACACAGTTGTGTCAGAAGCAA...\n", + " dna\n", + " HBB promoter\n", + " GCF_000001405.26\n", + " None\n", + " Regulatory\n", + " \n", + " \n", " ...\n", " ...\n", " ...\n", @@ -306,17 +314,27 @@ " ...\n", " \n", " \n", - " 158\n", - " urn:mavedb:00000072-a-1\n", - " GQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQ...\n", + " 204\n", + " urn:mavedb:00000107-a-1\n", + " MDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRS...\n", + " protein\n", + " PSAT1\n", + " GCF_000001405.26\n", + " None\n", + " Protein coding\n", + " \n", + " \n", + " 205\n", + " urn:mavedb:00000103-d-1\n", + " MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNV...\n", " protein\n", - " IGHG1\n", + " MAPK1\n", " GCF_000001405.26\n", - " P01857\n", + " None\n", " Protein coding\n", " \n", " \n", - " 159\n", + " 206\n", " urn:mavedb:00000029-a-2\n", " GAACTGGAAAAGCCCTGTCCGGTGAGGGGGCAGAAGGACTCAGCGC...\n", " dna\n", @@ -326,7 +344,7 @@ " Regulatory\n", " \n", " \n", - " 160\n", + " 207\n", " urn:mavedb:00000061-b-1\n", " TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAA...\n", " dna\n", @@ -336,28 +354,18 @@ " Protein coding\n", " \n", " \n", - " 161\n", - " urn:mavedb:00000095-b-1\n", - " ATGGATTCTCTTGTGGTCCTTGTGCTCTGTCTCTCATGTTTGCTTC...\n", - " dna\n", - " CYP2C9\n", - " GCF_000001405.26\n", - " P11712\n", - " Protein coding\n", - " \n", - " \n", - " 162\n", - " urn:mavedb:00000001-a-1\n", - " ATGTCGGGGATCGCCCTCAGCAGACTCGCCCAGGAGAGGAAAGCAT...\n", + " 208\n", + " urn:mavedb:00000097-q-1\n", + " TTTCTTTCAGCATGATTTTGAAGTCAGAGGAGATGTGGTCAATGGA...\n", " dna\n", - " UBE2I\n", - " GCF_000001405.26\n", - " P63279\n", + " BRCA1 Exon 19\n", + " GCF_000001405.13\n", + " None\n", " Protein coding\n", " \n", " \n", "\n", - "

163 rows × 7 columns

\n", + "

209 rows × 7 columns

\n", "" ], "text/plain": [ @@ -365,42 +373,42 @@ "0 urn:mavedb:00000041-a-1 \n", "1 urn:mavedb:00000048-a-1 \n", "2 urn:mavedb:00000068-b-1 \n", - "3 urn:mavedb:00000023-a-1 \n", - "4 urn:mavedb:00000045-c-1 \n", + "3 urn:mavedb:00000045-c-1 \n", + "4 urn:mavedb:00000018-a-1 \n", ".. ... \n", - "158 urn:mavedb:00000072-a-1 \n", - "159 urn:mavedb:00000029-a-2 \n", - "160 urn:mavedb:00000061-b-1 \n", - "161 urn:mavedb:00000095-b-1 \n", - "162 urn:mavedb:00000001-a-1 \n", + "204 urn:mavedb:00000107-a-1 \n", + "205 urn:mavedb:00000103-d-1 \n", + "206 urn:mavedb:00000029-a-2 \n", + "207 urn:mavedb:00000061-b-1 \n", + "208 urn:mavedb:00000097-q-1 \n", "\n", " target_sequence target_sequence_type \\\n", "0 CTGCGGCTGGAGGTCAAGCTGGGCCAGGGCTGCTTTGGCGAGGTGT... dna \n", "1 GAGGGGATCAGTATATACACTTCAGATAACTACACCGAGGAAATGG... dna \n", "2 ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTC... dna \n", - "3 AGCTCTTCACCGGAGACCCAAATACAACAAATCAAGTCGCCTGCCC... dna \n", - "4 ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTG... dna \n", + "3 ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTG... dna \n", + "4 GGTGTCTGTTTGAGGTTGCTAGTGAACACAGTTGTGTCAGAAGCAA... dna \n", ".. ... ... \n", - "158 GQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQ... protein \n", - "159 GAACTGGAAAAGCCCTGTCCGGTGAGGGGGCAGAAGGACTCAGCGC... dna \n", - "160 TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAA... dna \n", - "161 ATGGATTCTCTTGTGGTCCTTGTGCTCTGTCTCTCATGTTTGCTTC... dna \n", - "162 ATGTCGGGGATCGCCCTCAGCAGACTCGCCCAGGAGAGGAAAGCAT... dna \n", + "204 MDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRS... protein \n", + "205 MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNV... protein \n", + "206 GAACTGGAAAAGCCCTGTCCGGTGAGGGGGCAGAAGGACTCAGCGC... dna \n", + "207 TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAA... dna \n", + "208 TTTCTTTCAGCATGATTTTGAAGTCAGAGGAGATGTGGTCAATGGA... dna \n", "\n", " target assembly_id uniprot_id target_type \n", "0 Src catalytic domain GCF_000001405.26 P12931 Protein coding \n", "1 CXCR4 GCF_000001405.26 P61073 Protein coding \n", "2 TP53 (P72R) GCF_000001405.26 None Protein coding \n", - "3 LDLR promoter GCF_000001405.26 None Regulatory \n", - "4 alpha-synuclein GCF_000001405.10 P37840 Protein coding \n", + "3 alpha-synuclein GCF_000001405.10 P37840 Protein coding \n", + "4 HBB promoter GCF_000001405.26 None Regulatory \n", ".. ... ... ... ... \n", - "158 IGHG1 GCF_000001405.26 P01857 Protein coding \n", - "159 SORT1 enhancer GCF_000001405.26 None Regulatory \n", - "160 RAF GCF_000001405.26 P04049 Protein coding \n", - "161 CYP2C9 GCF_000001405.26 P11712 Protein coding \n", - "162 UBE2I GCF_000001405.26 P63279 Protein coding \n", + "204 PSAT1 GCF_000001405.26 None Protein coding \n", + "205 MAPK1 GCF_000001405.26 None Protein coding \n", + "206 SORT1 enhancer GCF_000001405.26 None Regulatory \n", + "207 RAF GCF_000001405.26 P04049 Protein coding \n", + "208 BRCA1 Exon 19 GCF_000001405.13 None Protein coding \n", "\n", - "[163 rows x 7 columns]" + "[209 rows x 7 columns]" ] }, "execution_count": 9, @@ -413,6 +421,7 @@ "dat = {'urn': urns, 'target_sequence': human_target_sequences, 'target_sequence_type': target_type, 'target':human_targets, \n", " 'assembly_id':human_assembly, 'uniprot_id':uniprot, 'target_type':targets}\n", "dat = pd.DataFrame(data=dat)\n", + "dat.to_csv('results/mave_dat.csv')\n", "dat" ] }, @@ -499,36 +508,31 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 318 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1971 bases in 1 sequences\n", + "Searched 187 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1443 bases in 1 sequences\n", + "Searched 1047 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", + "Searched 450 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 495 bases in 1 sequences\n", + "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 187 bases in 1 sequences\n", + "Searched 2805 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -536,58 +540,50 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 450 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Searched 51 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1971 bases in 1 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 477 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Searched 93 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 2805 bases in 1 sequences\n", + "Searched 495 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 51 bases in 1 sequences\n", + "Searched 3958 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 117 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 909 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 470 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Searched 1656 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1461 bases in 1 sequences\n", + "Searched 51 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1656 bases in 1 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 579 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 51 bases in 1 sequences\n", + "Searched 1086 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 495 bases in 1 sequences\n", + "Searched 477 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", @@ -596,52 +592,38 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1182 bases in 1 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 93 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 495 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 51 bases in 1 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1656 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 51 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 600 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 477 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 93 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", + "Searched 117 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 600 bases in 1 sequences\n", + "Searched 81 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -649,42 +631,21 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 738 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n" - ] - }, - { - "name": "stdout", - "output_type": "stream", - "text": [ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 93 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 300 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 117 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 477 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 81 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Searched 104 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -693,28 +654,20 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", "Searched 450 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 423 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1398 bases in 1 sequences\n", "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 909 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -732,50 +685,29 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 51 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 927 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 470 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 102 bases in 1 sequences\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 117 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 2667 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 259 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -783,32 +715,16 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 2667 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 259 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 45 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 927 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -819,18 +735,15 @@ "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", "Searched 1053 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n" - ] - }, - { - "name": "stdout", - "output_type": "stream", - "text": [ + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -838,10 +751,7 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 249 bases in 1 sequences\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Searched 101 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -849,242 +759,120 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1242 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Searched 78414 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 117 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1212 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 601 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1344 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 451 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 259 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1053 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 909 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1212 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 573 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 117 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 51 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1053 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 2667 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 303 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 600 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 423 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 573 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 463 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 81 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 51 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1182 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1656 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 117 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 51 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n" - ] - }, - { - "name": "stdout", - "output_type": "stream", - "text": [ "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 274 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 600 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 495 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 306 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 117 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 585 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 495 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 495 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 585 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 385 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1656 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 51 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 591 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 259 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 285 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 620 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", @@ -1135,29 +923,50 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 109 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 117 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1344 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 451 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1086 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 259 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 573 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n" + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n" ] }, { @@ -1166,15 +975,28 @@ "text": [ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 51 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 106 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 100 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", @@ -1186,55 +1008,99 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 109 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 463 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 51 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 51 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 600 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 106 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 108 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1212 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 306 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 117 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 585 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 101 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 100 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 495 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 591 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1212 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 249 bases in 1 sequences\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", @@ -1242,26 +1108,48 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 105 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1053 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 259 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 72 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 98 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 306 bases in 1 sequences\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", @@ -1273,47 +1161,60 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 100 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 495 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 51 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 100 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 591 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1470 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 477 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 318 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 249 bases in 1 sequences\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n" - ] - }, - { - "name": "stdout", - "output_type": "stream", - "text": [ - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Searched 1443 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -1321,44 +1222,43 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1053 bases in 1 sequences\n", + "Searched 495 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1053 bases in 1 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1470 bases in 1 sequences\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", + "Searched 117 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 477 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 259 bases in 1 sequences\n", + "Searched 51 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 600 bases in 1 sequences\n", + "Searched 909 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 72 bases in 1 sequences\n", + "Searched 470 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 601 bases in 1 sequences\n", + "Searched 1461 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1971 bases in 1 sequences\n", + "Searched 100 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -1366,42 +1266,31 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 306 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Searched 579 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 909 bases in 1 sequences\n", + "Searched 495 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 600 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1656 bases in 1 sequences\n", + "Searched 1182 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 486 bases in 1 sequences\n", + "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 318 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 102 bases in 1 sequences\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 3958 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 495 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", @@ -1410,15 +1299,20 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 591 bases in 1 sequences\n", - "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Searched 1971 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Searched 423 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", - "Loaded 3209286105 letters in 455 sequences\n", - "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 600 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", @@ -1426,389 +1320,2320 @@ "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 117 bases in 1 sequences\n", + "Searched 738 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", - "Searched 1470 bases in 1 sequences\n", + "Searched 300 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "Loaded 3209286105 letters in 455 sequences\n", "Searched 477 bases in 1 sequences\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 423 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1086 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1398 bases in 1 sequences\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 909 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 100 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 51 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 927 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 100 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 108 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 470 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 102 bases in 1 sequences\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 117 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 2667 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 259 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 2667 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 259 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 423 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 45 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 105 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 100 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 927 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 249 bases in 1 sequences\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", "***Using Gene Database Endpoint: http://localhost:8000***\n" ] - } - ], - "source": [ - "# Get Query and Hit Ranges for Each Human Target Sequence\n", - "from Bio import SearchIO\n", - "mave_blat_dict = {}\n", - "\n", - "for i in range(len(dat.index)):\n", - " blat_file = open('blat_query.fa', 'w')\n", - " blat_file.write('>' + dat.at[i, 'target'] + '\\n')\n", - " blat_file.write(dat.at[i, 'target_sequence'] + '\\n')\n", - " blat_file.close()\n", - "\n", - " if dat.at[i, 'target_sequence_type'] == 'protein':\n", - " !./blat hg38.2bit -q=prot -t=dnax blat_query.fa blat_out.psl\n", - " else:\n", - " !./blat hg38.2bit blat_query.fa blat_out.psl\n", - "\n", - " # Extract ranges\n", - " chrom = ''\n", - " strand = ''\n", - " target = ''\n", - " target_type = ''\n", - " coverage = None\n", - " identity = None\n", - " query_ranges = list()\n", - " hit_ranges = list()\n", - " \n", - " try:\n", - " output = SearchIO.read('blat_out.psl', 'blat-psl')\n", - " except:\n", - " try:\n", - " !./blat hg38.2bit -q=dnax -t=dnax blat_query.fa blat_out.psl \n", - " output = SearchIO.read('blat_out.psl', 'blat-psl')\n", - " except:\n", - " qh_dat = {'query_ranges': list('NA'), 'hit_ranges': list('NA')}\n", - " qh_dat = pd.DataFrame(data = qh_dat)\n", - " mave_blat_dict[dat.at[i, 'urn']] = {'chrom': 'NA', 'strand': 'NA', 'target': 'NA', 'target_type': 'NA',\n", - " 'uniprot': 'NA','coverage': 'NA','identity':'NA', 'hits': qh_dat}\n", - " continue\n", - "\n", - " # Find chromosome to select hit from\n", - " hit_scores = list()\n", - " hit_dict = {}\n", - " use_chr = False\n", - " \n", - " for c in range(len(output)):\n", - " correct_chr = get_gene_data(i,output[c].id.strip('chr'), return_chr = True)\n", - " if correct_chr == output[c].id.strip('chr'):\n", - " use_chr = True\n", - " break\n", - " if correct_chr == 'NA': # Take top scoring hit if target not found using gene normalizer\n", - " hit_scores = list()\n", - " for e in range(len(output[c])):\n", - " hit_scores.append(output[c][e].score)\n", - " hit_dict[c] = hit_scores\n", - "\n", - " if use_chr == False:\n", - " for key in hit_dict:\n", - " hit_dict[key] = max(hit_dict[key])\n", - " hit = max(hit_dict, key = hit_dict.get)\n", - " else:\n", - " hit = c\n", - " \n", - " \n", - " # Use location provided by gene normalizer to find hsp\n", - " loc_dict = get_gene_data(i, output[hit].id.strip('chr'), return_chr = False)\n", - " \n", - " hit_starts = list()\n", - " for n in range(len(output[hit])):\n", - " hit_starts.append(output[hit][n].hit_start)\n", - " \n", - " sub_scores = list()\n", - " for n in range(len(output[hit])):\n", - " sub_scores.append(output[hit][n].score)\n", - " \n", - " if loc_dict == 'NA':\n", - " hsp = output[hit][sub_scores.index(max(sub_scores))] # Take top score if no match found \n", - " else:\n", - " hsp = output[hit][hit_starts.index(min(hit_starts, key=lambda x:abs(x - loc_dict['start'])))]\n", - "\n", - " \n", - " for j in range(len(hsp)):\n", - " test_file = open('blat_output_test.txt', 'w')\n", - " test_file.write(str(hsp[j]))\n", - " test_file.close()\n", - "\n", - " query_string = ''\n", - " hit_string = ''\n", - " strand = hsp[0].query_strand\n", - " coverage = 100 * (hsp.query_end - hsp.query_start) / output.seq_len\n", - " coverage = f\"{hsp.query_end - hsp.query_start} / {output.seq_len}, {coverage}\" \n", - " identity = hsp.ident_pct\n", - "\n", - " test_file = open('blat_output_test.txt', 'r')\n", - " for k,line in enumerate(test_file):\n", - " if k == 1:\n", - " chrom = line.strip('\\n')\n", - " if k == 2:\n", - " query_string = line.strip('\\n')\n", - " if k == 3:\n", - " hit_string = line.strip('\\n')\n", - " test_file.close()\n", - "\n", - " chrom = chrom.split(' ')[9].strip('chr')\n", - " query_string = query_string.split(' ')\n", - " hit_string = hit_string.split(' ')\n", - " query_ranges.append(query_string[2])\n", - " hit_ranges.append(hit_string[4])\n", - " \n", - " # Add to dict\n", - " qh_dat = {'query_ranges': query_ranges, 'hit_ranges': hit_ranges}\n", - " qh_dat = pd.DataFrame(data = qh_dat)\n", - " mave_blat_dict[dat.at[i, 'urn']] = {'chrom': chrom,'strand': strand,'target': dat.at[i,'target'], 'target_type': dat.at[i, 'target_type'],\n", - " 'uniprot': dat.at[i,'uniprot_id'],'coverage': coverage,'identity': identity, 'hits': qh_dat} " - ] - }, - { - "cell_type": "code", - "execution_count": 12, - "id": "e199a3d9", - "metadata": {}, - "outputs": [ + }, { - "data": { - "text/plain": [ - "{'urn:mavedb:00000041-a-1': {'chrom': '20',\n", - " 'strand': 1,\n", - " 'target': 'Src catalytic domain',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P12931',\n", - " 'coverage': '750 / 750, 100.0',\n", - " 'identity': 99.86666666666666,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:52] [37397802:37397854]\n", - " 1 [52:232] [37400114:37400294]\n", - " 2 [232:309] [37401601:37401678]\n", - " 3 [309:463] [37402434:37402588]\n", - " 4 [463:595] [37402748:37402880]\n", - " 5 [595:750] [37403170:37403325]},\n", - " 'urn:mavedb:00000048-a-1': {'chrom': '2',\n", - " 'strand': -1,\n", - " 'target': 'CXCR4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P61073',\n", - " 'coverage': '1041 / 1053, 98.86039886039886',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [12:1053] [136114871:136115912]},\n", - " 'urn:mavedb:00000068-b-1': {'chrom': '17',\n", - " 'strand': -1,\n", - " 'target': 'TP53 (P72R)',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '1180 / 1182, 99.83079526226734',\n", - " 'identity': 99.91525423728814,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [1100:1180] [7669610:7669690]\n", - " 1 [993:1100] [7670608:7670715]\n", - " 2 [919:993] [7673534:7673608]\n", - " 3 [782:919] [7673700:7673837]\n", - " 4 [672:782] [7674180:7674290]\n", - " 5 [559:672] [7674858:7674971]\n", - " 6 [375:559] [7675052:7675236]\n", - " 7 [96:375] [7675993:7676272]\n", - " 8 [74:96] [7676381:7676403]\n", - " 9 [0:74] [7676520:7676594]},\n", - " 'urn:mavedb:00000023-a-1': {'chrom': '19',\n", - " 'strand': 1,\n", - " 'target': 'LDLR promoter',\n", - " 'target_type': 'Regulatory',\n", - " 'uniprot': None,\n", - " 'coverage': '318 / 318, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:318] [11089230:11089548]},\n", - " 'urn:mavedb:00000045-c-1': {'chrom': '4',\n", - " 'strand': -1,\n", - " 'target': 'alpha-synuclein',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P37840',\n", - " 'coverage': '423 / 423, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [390:423] [89726627:89726660]\n", - " 1 [306:390] [89729193:89729277]\n", - " 2 [163:306] [89822245:89822388]\n", - " 3 [121:163] [89828142:89828184]\n", - " 4 [0:121] [89835546:89835667]},\n", - " 'urn:mavedb:00000049-a-2': {'chrom': '1',\n", - " 'strand': -1,\n", - " 'target': 'MTHFR',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P42898',\n", - " 'coverage': '1971 / 1971, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [1752:1971] [11790679:11790898]\n", - " 1 [1632:1752] [11791206:11791326]\n", - " 2 [1530:1632] [11792277:11792379]\n", - " 3 [1347:1530] [11793906:11794089]\n", - " 4 [1166:1347] [11794357:11794538]\n", - " 5 [1031:1166] [11794728:11794863]\n", - " 6 [780:1031] [11795097:11795348]\n", - " 7 [586:780] [11796205:11796399]\n", - " 8 [475:586] [11800211:11800322]\n", - " 9 [236:475] [11801160:11801399]\n", - " 10 [0:236] [11802880:11803116]},\n", - " 'urn:mavedb:00000062-b-1': {'chrom': '10',\n", - " 'strand': 1,\n", - " 'target': 'CYP2C19',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P33261',\n", - " 'coverage': '1443 / 1443, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:144] [94762729:94762873]\n", - " 1 [144:307] [94775057:94775220]\n", - " 2 [307:457] [94775389:94775539]\n", - " 3 [457:618] [94780498:94780659]\n", - " 4 [618:795] [94781820:94781997]\n", - " 5 [795:937] [94820495:94820637]\n", - " 6 [937:1125] [94842836:94843024]\n", - " 7 [1125:1267] [94849916:94850058]\n", - " 8 [1267:1443] [94852732:94852908]},\n", - " 'urn:mavedb:00000094-a-12': {'chrom': '1',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '695 / 695, 100.0',\n", - " 'identity': 99.9519692603266,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:104] [40784093:40784405]\n", - " 1 [105:135] [40817265:40817355]\n", - " 2 [135:177] [40818163:40818289]\n", - " 3 [177:236] [40818503:40818680]\n", - " 4 [236:278] [40819346:40819472]\n", - " 5 [278:315] [40819874:40819985]\n", - " 6 [315:346] [40820164:40820257]\n", - " 7 [346:376] [40822310:40822400]\n", - " 8 [376:430] [40824094:40824256]\n", - " 9 [430:504] [40831081:40831303]\n", - " 10 [504:537] [40833012:40833111]\n", - " 11 [537:581] [40834964:40835096]\n", - " 12 [581:624] [40837662:40837791]\n", - " 13 [624:695] [40838307:40838520]},\n", - " 'urn:mavedb:00000057-c-1': {'chrom': '11',\n", - " 'strand': -1,\n", - " 'target': 'Ras',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P01112',\n", - " 'coverage': '495 / 495, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [447:495] [532707:532755]\n", - " 1 [287:447] [533452:533612]\n", - " 2 [108:287] [533765:533944]\n", - " 3 [0:108] [534211:534319]},\n", - " 'urn:mavedb:00000094-a-7': {'chrom': '1',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '695 / 695, 100.0',\n", - " 'identity': 99.9519692603266,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:104] [40784093:40784405]\n", - " 1 [105:135] [40817265:40817355]\n", - " 2 [135:177] [40818163:40818289]\n", - " 3 [177:236] [40818503:40818680]\n", - " 4 [236:278] [40819346:40819472]\n", - " 5 [278:315] [40819874:40819985]\n", - " 6 [315:346] [40820164:40820257]\n", - " 7 [346:376] [40822310:40822400]\n", - " 8 [376:430] [40824094:40824256]\n", - " 9 [430:504] [40831081:40831303]\n", - " 10 [504:537] [40833012:40833111]\n", - " 11 [537:581] [40834964:40835096]\n", - " 12 [581:624] [40837662:40837791]\n", - " 13 [624:695] [40838307:40838520]},\n", - " 'urn:mavedb:00000018-a-1': {'chrom': '11',\n", - " 'strand': 1,\n", - " 'target': 'HBB promoter',\n", - " 'target_type': 'Regulatory',\n", - " 'uniprot': None,\n", - " 'coverage': '187 / 187, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:187] [5227021:5227208]},\n", - " 'urn:mavedb:00000061-f-1': {'chrom': '3',\n", - " 'strand': -1,\n", - " 'target': 'RAF',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P04049',\n", - " 'coverage': '117 / 117, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [54:117] [12611999:12612062]\n", - " 1 [0:54] [12618514:12618568]},\n", - " 'urn:mavedb:00000001-c-1': {'chrom': '14',\n", - " 'strand': 1,\n", - " 'target': 'CALM1',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P0DP23',\n", - " 'coverage': '448 / 450, 99.55555555555556',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [2:34] [90400063:90400095]\n", - " 1 [34:178] [90401258:90401402]\n", - " 2 [178:285] [90403861:90403968]\n", - " 3 [285:421] [90404378:90404514]\n", - " 4 [421:450] [90404688:90404717]},\n", - " 'urn:mavedb:00000049-a-3': {'chrom': '1',\n", - " 'strand': -1,\n", - " 'target': 'MTHFR',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P42898',\n", - " 'coverage': '1971 / 1971, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [1752:1971] [11790679:11790898]\n", - " 1 [1632:1752] [11791206:11791326]\n", - " 2 [1530:1632] [11792277:11792379]\n", - " 3 [1347:1530] [11793906:11794089]\n", - " 4 [1166:1347] [11794357:11794538]\n", - " 5 [1031:1166] [11794728:11794863]\n", - " 6 [780:1031] [11795097:11795348]\n", - " 7 [586:780] [11796205:11796399]\n", - " 8 [475:586] [11800211:11800322]\n", - " 9 [236:475] [11801160:11801399]\n", - " 10 [0:236] [11802880:11803116]},\n", - " 'urn:mavedb:00000001-a-2': {'chrom': '16',\n", - " 'strand': 1,\n", - " 'target': 'UBE2I',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P63279',\n", - " 'coverage': '477 / 477, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:66] [1314030:1314096]\n", - " 1 [66:150] [1314292:1314376]\n", - " 2 [150:223] [1315653:1315726]\n", - " 3 [223:333] [1320173:1320283]\n", - " 4 [333:413] [1320437:1320517]\n", - " 5 [413:477] [1324729:1324793]},\n", - " 'urn:mavedb:00000050-a-1': {'chrom': '2',\n", - " 'strand': 1,\n", - " 'target': 'MSH2',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P43246',\n", - " 'coverage': '2805 / 2805, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:211] [47403191:47403402]\n", - " 1 [211:366] [47408400:47408555]\n", - " 2 [366:645] [47410093:47410372]\n", - " 3 [645:792] [47412413:47412560]\n", - " 4 [792:942] [47414268:47414418]\n", - " 5 [942:1076] [47416295:47416429]\n", - " 6 [1076:1276] [47429741:47429941]\n", - " 7 [1276:1386] [47445547:47445657]\n", - " 8 [1386:1510] [47463030:47463154]\n", - " 9 [1510:1661] [47466657:47466808]\n", - " 10 [1661:1759] [47470964:47471062]\n", + "name": "stdout", + "output_type": "stream", + "text": [ + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1242 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1212 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 601 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 108 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 423 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 106 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1053 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 909 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1212 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 117 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1053 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 2667 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 303 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 600 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 423 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 573 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 81 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1182 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1656 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 117 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 274 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 495 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 495 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 98 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 585 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 385 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1656 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 51 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 259 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 285 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 620 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 423 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1053 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1470 bases in 1 sequences\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 600 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 601 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1971 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 108 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1656 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 106 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 909 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 600 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 1656 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 486 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 318 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 102 bases in 1 sequences\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Blatx 455 sequences in database, 1 files in query\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 600 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 117 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "Loaded 3209286105 letters in 455 sequences\n", + "Searched 104 bases in 1 sequences\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "***Using Gene Database Endpoint: http://localhost:8000***\n" + ] + } + ], + "source": [ + "# Get Query and Hit Ranges for Each Human Target Sequence\n", + "from Bio import SearchIO\n", + "mave_blat_dict = {}\n", + "\n", + "for i in range(len(dat.index)):\n", + " blat_file = open('blat_query.fa', 'w')\n", + " blat_file.write('>' + dat.at[i, 'target'] + '\\n')\n", + " blat_file.write(dat.at[i, 'target_sequence'] + '\\n')\n", + " blat_file.close()\n", + "\n", + " if dat.at[i, 'target_sequence_type'] == 'protein':\n", + " !./blat hg38.2bit -q=prot -t=dnax -minScore=20 blat_query.fa blat_out.psl\n", + " else:\n", + " !./blat hg38.2bit -minScore=20 blat_query.fa blat_out.psl\n", + "\n", + " # Extract ranges\n", + " chrom = ''\n", + " strand = ''\n", + " target = ''\n", + " target_type = ''\n", + " coverage = None\n", + " identity = None\n", + " query_ranges = list()\n", + " hit_ranges = list()\n", + " \n", + " try:\n", + " output = SearchIO.read('blat_out.psl', 'blat-psl')\n", + " except:\n", + " try:\n", + " !./blat hg38.2bit -q=dnax -t=dnax -minScore=20 blat_query.fa blat_out.psl \n", + " output = SearchIO.read('blat_out.psl', 'blat-psl')\n", + " except:\n", + " qh_dat = {'query_ranges': list('NA'), 'hit_ranges': list('NA')}\n", + " qh_dat = pd.DataFrame(data = qh_dat)\n", + " mave_blat_dict[dat.at[i, 'urn']] = {'chrom': 'NA', 'strand': 'NA', 'target': 'NA', 'target_type': 'NA',\n", + " 'uniprot': 'NA','coverage': 'NA','identity':'NA', 'hits': qh_dat}\n", + " continue\n", + "\n", + " # Find chromosome to select hit from\n", + " hit_scores = list()\n", + " hit_dict = {}\n", + " use_chr = False\n", + " \n", + " for c in range(len(output)):\n", + " correct_chr = get_gene_data(i,output[c].id.strip('chr'), return_chr = True)\n", + " if correct_chr == output[c].id.strip('chr'):\n", + " use_chr = True\n", + " break\n", + " if correct_chr == 'NA': # Take top scoring hit if target not found using gene normalizer\n", + " hit_scores = list()\n", + " for e in range(len(output[c])):\n", + " hit_scores.append(output[c][e].score)\n", + " hit_dict[c] = hit_scores\n", + "\n", + " if use_chr == False:\n", + " for key in hit_dict:\n", + " hit_dict[key] = max(hit_dict[key])\n", + " hit = max(hit_dict, key = hit_dict.get)\n", + " else:\n", + " hit = c\n", + " \n", + " \n", + " # Use location provided by gene normalizer to find hsp\n", + " loc_dict = get_gene_data(i, output[hit].id.strip('chr'), return_chr = False)\n", + " \n", + " hit_starts = list()\n", + " for n in range(len(output[hit])):\n", + " hit_starts.append(output[hit][n].hit_start)\n", + " \n", + " sub_scores = list()\n", + " for n in range(len(output[hit])):\n", + " sub_scores.append(output[hit][n].score)\n", + " \n", + " if loc_dict == 'NA':\n", + " hsp = output[hit][sub_scores.index(max(sub_scores))] # Take top score if no match found \n", + " else:\n", + " hsp = output[hit][hit_starts.index(min(hit_starts, key=lambda x:abs(x - loc_dict['start'])))]\n", + "\n", + " \n", + " for j in range(len(hsp)):\n", + " test_file = open('blat_output_test.txt', 'w')\n", + " test_file.write(str(hsp[j]))\n", + " test_file.close()\n", + "\n", + " query_string = ''\n", + " hit_string = ''\n", + " strand = hsp[0].query_strand\n", + " coverage = 100 * (hsp.query_end - hsp.query_start) / output.seq_len\n", + " coverage = f\"{hsp.query_end - hsp.query_start} / {output.seq_len}, {coverage}\" \n", + " identity = hsp.ident_pct\n", + "\n", + " test_file = open('blat_output_test.txt', 'r')\n", + " for k,line in enumerate(test_file):\n", + " if k == 1:\n", + " chrom = line.strip('\\n')\n", + " if k == 2:\n", + " query_string = line.strip('\\n')\n", + " if k == 3:\n", + " hit_string = line.strip('\\n')\n", + " test_file.close()\n", + "\n", + " chrom = chrom.split(' ')[9].strip('chr')\n", + " query_string = query_string.split(' ')\n", + " hit_string = hit_string.split(' ')\n", + " query_ranges.append(query_string[2])\n", + " hit_ranges.append(hit_string[4])\n", + " \n", + " # Add to dict\n", + " qh_dat = {'query_ranges': query_ranges, 'hit_ranges': hit_ranges}\n", + " qh_dat = pd.DataFrame(data = qh_dat)\n", + " mave_blat_dict[dat.at[i, 'urn']] = {'chrom': chrom,'strand': strand,'target': dat.at[i,'target'], 'target_type': dat.at[i, 'target_type'],\n", + " 'uniprot': dat.at[i,'uniprot_id'],'coverage': coverage,'identity': identity, 'hits': qh_dat} " + ] + }, + { + "cell_type": "code", + "execution_count": 12, + "id": "e199a3d9", + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "{'urn:mavedb:00000041-a-1': {'chrom': '20',\n", + " 'strand': 1,\n", + " 'target': 'Src catalytic domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P12931',\n", + " 'coverage': '750 / 750, 100.0',\n", + " 'identity': 99.86666666666666,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:52] [37397802:37397854]\n", + " 1 [52:232] [37400114:37400294]\n", + " 2 [232:309] [37401601:37401678]\n", + " 3 [309:463] [37402434:37402588]\n", + " 4 [463:595] [37402748:37402880]\n", + " 5 [595:750] [37403170:37403325]},\n", + " 'urn:mavedb:00000048-a-1': {'chrom': '2',\n", + " 'strand': -1,\n", + " 'target': 'CXCR4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P61073',\n", + " 'coverage': '1041 / 1053, 98.86039886039886',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [12:1053] [136114871:136115912]},\n", + " 'urn:mavedb:00000068-b-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'TP53 (P72R)',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '1180 / 1182, 99.83079526226734',\n", + " 'identity': 99.91525423728814,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1100:1180] [7669610:7669690]\n", + " 1 [993:1100] [7670608:7670715]\n", + " 2 [919:993] [7673534:7673608]\n", + " 3 [782:919] [7673700:7673837]\n", + " 4 [672:782] [7674180:7674290]\n", + " 5 [559:672] [7674858:7674971]\n", + " 6 [375:559] [7675052:7675236]\n", + " 7 [96:375] [7675993:7676272]\n", + " 8 [74:96] [7676381:7676403]\n", + " 9 [0:74] [7676520:7676594]},\n", + " 'urn:mavedb:00000045-c-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000018-a-1': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'HBB promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '187 / 187, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:187] [5227021:5227208]},\n", + " 'urn:mavedb:00000099-a-1': {'chrom': '3',\n", + " 'strand': 1,\n", + " 'target': 'RHO',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '1047 / 1047, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:361] [129528733:129529094]\n", + " 1 [361:530] [129530875:129531044]\n", + " 2 [530:696] [129532250:129532416]\n", + " 3 [696:936] [129532532:129532772]\n", + " 4 [936:1047] [129533607:129533718]},\n", + " 'urn:mavedb:00000001-c-1': {'chrom': '14',\n", + " 'strand': 1,\n", + " 'target': 'CALM1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P0DP23',\n", + " 'coverage': '448 / 450, 99.55555555555556',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [2:34] [90400063:90400095]\n", + " 1 [34:178] [90401258:90401402]\n", + " 2 [178:285] [90403861:90403968]\n", + " 3 [285:421] [90404378:90404514]\n", + " 4 [421:450] [90404688:90404717]},\n", + " 'urn:mavedb:00000049-a-3': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000050-a-1': {'chrom': '2',\n", + " 'strand': 1,\n", + " 'target': 'MSH2',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P43246',\n", + " 'coverage': '2805 / 2805, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:211] [47403191:47403402]\n", + " 1 [211:366] [47408400:47408555]\n", + " 2 [366:645] [47410093:47410372]\n", + " 3 [645:792] [47412413:47412560]\n", + " 4 [792:942] [47414268:47414418]\n", + " 5 [942:1076] [47416295:47416429]\n", + " 6 [1076:1276] [47429741:47429941]\n", + " 7 [1276:1386] [47445547:47445657]\n", + " 8 [1386:1510] [47463030:47463154]\n", + " 9 [1510:1661] [47466657:47466808]\n", + " 10 [1661:1759] [47470964:47471062]\n", " 11 [1759:2005] [47475024:47475270]\n", " 12 [2005:2210] [47476366:47476571]\n", " 13 [2210:2458] [47478271:47478519]\n", " 14 [2458:2634] [47480695:47480871]\n", " 15 [2634:2805] [47482778:47482949]},\n", + " 'urn:mavedb:00000061-i-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000083-b-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - SRSF1 (ASF/SF2) binding site',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '41 / 51, 80.3921568627451',\n", + " 'identity': 97.5609756097561,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [10:51] [32416489:32416530]},\n", + " 'urn:mavedb:00000094-a-5': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000043-a-2': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'S505N MPL',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P40238',\n", + " 'coverage': '93 / 93, 100.0',\n", + " 'identity': 98.9247311827957,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:10] [43348992:43349002]\n", + " 1 [10:93] [43349262:43349345]},\n", + " 'urn:mavedb:00000055-0-1': {'chrom': '13',\n", + " 'strand': 1,\n", + " 'target': 'NUDT15',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9NV35',\n", + " 'coverage': '495 / 495, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:158] [48037746:48037904]\n", + " 1 [158:355] [48040919:48041116]\n", + " 2 [355:495] [48045659:48045799]},\n", + " 'urn:mavedb:00000104-a-2': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'PARP1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '3958 / 3958, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [3107:3958] [226360690:226361541]\n", + " 1 [2992:3107] [226361968:226362083]\n", + " 2 [2930:2992] [226363098:226363160]\n", + " 3 [2802:2930] [226363942:226364070]\n", + " 4 [2649:2802] [226365001:226365154]\n", + " 5 [2550:2649] [226365953:226366052]\n", + " 6 [2421:2550] [226367479:226367608]\n", + " 7 [2298:2421] [226368198:226368321]\n", + " 8 [2214:2298] [226370433:226370517]\n", + " 9 [2085:2214] [226374225:226374354]\n", + " 10 [1889:2085] [226377107:226377303]\n", + " 11 [1756:1889] [226379141:226379274]\n", + " 12 [1687:1756] [226379572:226379641]\n", + " 13 [1444:1687] [226379921:226380164]\n", + " 14 [1303:1444] [226381067:226381208]\n", + " 15 [1155:1303] [226383035:226383183]\n", + " 16 [978:1155] [226385503:226385680]\n", + " 17 [861:978] [226386325:226386442]\n", + " 18 [761:861] [226388655:226388755]\n", + " 19 [546:761] [226390409:226390624]\n", + " 20 [430:546] [226392198:226392314]\n", + " 21 [264:430] [226402213:226402379]\n", + " 22 [0:264] [226407809:226408073]},\n", + " 'urn:mavedb:00000005-a-6': {'chrom': '21',\n", + " 'strand': -1,\n", + " 'target': 'CBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P35520',\n", + " 'coverage': '1656 / 1656, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1552:1656] [43053879:43053983]\n", + " 1 [1467:1552] [43056802:43056887]\n", + " 2 [1358:1467] [43058144:43058253]\n", + " 3 [1223:1358] [43058833:43058968]\n", + " 4 [1145:1223] [43059225:43059303]\n", + " 5 [1039:1145] [43060440:43060546]\n", + " 6 [954:1039] [43062310:43062395]\n", + " 7 [828:954] [43062952:43063078]\n", + " 8 [736:828] [43063899:43063991]\n", + " 9 [666:736] [43065202:43065272]\n", + " 10 [531:666] [43065386:43065521]\n", + " 11 [451:531] [43065615:43065695]\n", + " 12 [316:451] [43066242:43066377]\n", + " 13 [209:316] [43068508:43068615]\n", + " 14 [0:209] [43071984:43072193]},\n", + " 'urn:mavedb:00000083-h-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - CG-containing enhancer',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '41 / 51, 80.3921568627451',\n", + " 'identity': 97.5609756097561,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [10:51] [32416489:32416530]},\n", + " 'urn:mavedb:00000098-a-1': {'chrom': '3',\n", + " 'strand': 0,\n", + " 'target': 'SCN5A',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q14524',\n", + " 'coverage': '12 / 12, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:12] [38551475:38551511]},\n", + " 'urn:mavedb:00000108-a-2': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'HMBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P08397',\n", + " 'coverage': '1086 / 1086, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:33] [119085033:119085066]\n", + " 1 [33:87] [119088254:119088308]\n", + " 2 [87:160] [119088634:119088707]\n", + " 3 [160:210] [119089081:119089131]\n", + " 4 [210:266] [119089216:119089272]\n", + " 5 [266:344] [119089682:119089760]\n", + " 6 [344:422] [119089989:119090067]\n", + " 7 [422:498] [119090189:119090265]\n", + " 8 [498:612] [119091412:119091526]\n", + " 9 [612:651] [119092124:119092163]\n", + " 10 [651:771] [119092403:119092523]\n", + " 11 [771:825] [119092757:119092811]\n", + " 12 [825:912] [119092934:119093021]\n", + " 13 [912:1086] [119093109:119093283]},\n", + " 'urn:mavedb:00000001-a-4': {'chrom': '16',\n", + " 'strand': 1,\n", + " 'target': 'UBE2I',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63279',\n", + " 'coverage': '477 / 477, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:66] [1314030:1314096]\n", + " 1 [66:150] [1314292:1314376]\n", + " 2 [150:223] [1315653:1315726]\n", + " 3 [223:333] [1320173:1320283]\n", + " 4 [333:413] [1320437:1320517]\n", + " 5 [413:477] [1324729:1324793]},\n", + " 'urn:mavedb:00000094-a-6': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000078-a-1': {'chrom': '16',\n", + " 'strand': 0,\n", + " 'target': 'VKOR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '163 / 163, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:57] [31094558:31094729]\n", + " 1 [57:94] [31093312:31093423]\n", + " 2 [94:163] [31091136:31091343]},\n", + " 'urn:mavedb:00000103-c-1': {'chrom': '22',\n", + " 'strand': 0,\n", + " 'target': 'MAPK1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '360 / 360, 100.0',\n", + " 'identity': 99.9071494893222,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:39] [21867323:21867440]\n", + " 1 [40:101] [21807662:21807845]\n", + " 2 [101:164] [21805849:21806038]\n", + " 3 [164:203] [21799011:21799128]\n", + " 4 [203:241] [21788694:21788808]\n", + " 5 [241:285] [21788257:21788389]\n", + " 6 [285:322] [21772872:21772983]\n", + " 7 [322:360] [21769206:21769320]},\n", + " 'urn:mavedb:00000043-a-1': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'MPL',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P40238',\n", + " 'coverage': '93 / 93, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:10] [43348992:43349002]\n", + " 1 [10:93] [43349262:43349345]},\n", + " 'urn:mavedb:00000061-d-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000046-a-1': {'chrom': '3',\n", + " 'strand': 1,\n", + " 'target': 'CD86',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42081',\n", + " 'coverage': '81 / 81, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:81] [122109290:122109371]},\n", + " 'urn:mavedb:00000081-a-1': {'chrom': '17',\n", + " 'strand': 0,\n", + " 'target': 'BRCA1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P38398',\n", + " 'coverage': '1863 / 1863, 100.0',\n", + " 'identity': 99.94623655913979,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:26] [43124018:43124096]\n", + " 1 [27:45] [43115724:43115778]\n", + " 2 [45:70] [43106457:43106532]\n", + " 3 [70:100] [43104868:43104958]\n", + " 4 [101:147] [43104121:43104259]\n", + " 5 [147:181] [43099778:43099880]\n", + " 6 [181:197] [43097245:43097293]\n", + " 7 [197:223] [43095846:43095924]\n", + " 8 [223:1365] [43091435:43094861]\n", + " 9 [1365:1395] [43090943:43091033]\n", + " 10 [1395:1451] [43082407:43082575]\n", + " 11 [1451:1494] [43076489:43076618]\n", + " 12 [1494:1558] [43074331:43074523]\n", + " 13 [1558:1662] [43070927:43071239]\n", + " 14 [1662:1691] [43067608:43067695]\n", + " 15 [1691:1717] [43063874:43063952]\n", + " 16 [1718:1731] [43063332:43063371]\n", + " 17 [1731:1759] [43057051:43057135]\n", + " 18 [1759:1777] [43051063:43051117]\n", + " 19 [1777:1802] [43049120:43049195]\n", + " 20 [1802:1822] [43047643:43047703]\n", + " 21 [1822:1863] [43045680:43045803]},\n", + " 'urn:mavedb:00000097-r-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 19',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '104 / 104, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [43057041:43057145]},\n", + " 'urn:mavedb:00000067-a-1': {'chrom': '19',\n", + " 'strand': 1,\n", + " 'target': 'TECR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9NZ01',\n", + " 'coverage': '916 / 927, 98.8133764832794',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [11:66] [14562520:14562575]\n", + " 1 [66:118] [14563205:14563257]\n", + " 2 [118:163] [14563657:14563702]\n", + " 3 [163:267] [14563799:14563903]\n", + " 4 [267:383] [14563981:14564097]\n", + " 5 [383:489] [14564181:14564287]\n", + " 6 [489:562] [14564785:14564858]\n", + " 7 [562:606] [14564948:14564992]\n", + " 8 [606:664] [14565065:14565123]\n", + " 9 [664:753] [14565201:14565290]\n", + " 10 [753:799] [14565617:14565663]\n", + " 11 [799:927] [14565743:14565871]},\n", + " 'urn:mavedb:00000001-c-2': {'chrom': '14',\n", + " 'strand': 1,\n", + " 'target': 'CALM1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P0DP23',\n", + " 'coverage': '448 / 450, 99.55555555555556',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [2:34] [90400063:90400095]\n", + " 1 [34:178] [90401258:90401402]\n", + " 2 [178:285] [90403861:90403968]\n", + " 3 [285:421] [90404378:90404514]\n", + " 4 [421:450] [90404688:90404717]},\n", + " 'urn:mavedb:00000049-a-7': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000060-a-2': {'chrom': '1',\n", + " 'strand': 1,\n", + " 'target': 'TARDBP',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q13148',\n", + " 'coverage': '1242 / 1242, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:238] [11013727:11013965]\n", + " 1 [238:402] [11016843:11017007]\n", + " 2 [402:543] [11018732:11018873]\n", + " 3 [543:714] [11020428:11020599]\n", + " 4 [714:1242] [11022123:11022651]},\n", + " 'urn:mavedb:00000058-a-1': {'chrom': '21',\n", + " 'strand': -1,\n", + " 'target': 'Aβ42',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P05067',\n", + " 'coverage': '126 / 126, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [51:126] [25891793:25891868]\n", + " 1 [0:51] [25897572:25897623]},\n", + " 'urn:mavedb:00000045-k-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000094-a-14': {'chrom': '11',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '676 / 676, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:129] [2445098:2445485]\n", + " 1 [129:159] [2527928:2528018]\n", + " 2 [159:201] [2570627:2570753]\n", + " 3 [201:227] [2571323:2571401]\n", + " 4 [227:260] [2572010:2572109]\n", + " 5 [260:307] [2572845:2572986]\n", + " 6 [307:344] [2583434:2583545]\n", + " 7 [344:375] [2585211:2585304]\n", + " 8 [375:417] [2587566:2587692]\n", + " 9 [417:462] [2588712:2588847]\n", + " 10 [462:505] [2661953:2662082]\n", + " 11 [505:529] [2768844:2768916]\n", + " 12 [529:561] [2775956:2776052]\n", + " 13 [561:577] [2776983:2777031]\n", + " 14 [577:598] [2777974:2778037]\n", + " 15 [598:676] [2847766:2848000]},\n", + " 'urn:mavedb:00000069-a-2': {'chrom': 'X',\n", + " 'strand': 0,\n", + " 'target': 'ACE2',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9BYF1',\n", + " 'coverage': '805 / 805, 100.0',\n", + " 'identity': 99.87531172069825,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:62] [15600725:15600911]\n", + " 1 [62:115] [15594844:15595003]\n", + " 2 [115:146] [15592229:15592322]\n", + " 3 [146:194] [15591713:15591857]\n", + " 4 [195:232] [15589343:15589454]\n", + " 5 [232:267] [15587753:15587858]\n", + " 6 [267:299] [15585477:15585573]\n", + " 7 [299:356] [15581222:15581393]\n", + " 8 [356:432] [15578089:15578317]\n", + " 9 [432:481] [15575664:15575811]\n", + " 10 [481:513] [15573368:15573464]\n", + " 11 [513:554] [15572202:15572325]\n", + " 12 [555:612] [15571624:15571795]\n", + " 13 [613:632] [15570294:15570351]\n", + " 14 [632:666] [15567724:15567826]\n", + " 15 [666:704] [15566254:15566368]\n", + " 16 [704:770] [15564022:15564220]\n", + " 17 [770:805] [15561907:15562012]},\n", + " 'urn:mavedb:00000106-b-1': {'chrom': '12',\n", + " 'strand': 0,\n", + " 'target': 'AID',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '196 / 198, 98.98989898989899',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [2:52] [8606864:8607014]\n", + " 1 [52:142] [8605215:8605485]\n", + " 2 [142:181] [8604806:8604923]\n", + " 3 [181:198] [8604286:8604337]},\n", + " 'urn:mavedb:00000046-a-2': {'chrom': '3',\n", + " 'strand': 1,\n", + " 'target': 'CD86',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42081',\n", + " 'coverage': '81 / 81, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:81] [122109290:122109371]},\n", + " 'urn:mavedb:00000069-a-1': {'chrom': 'X',\n", + " 'strand': 0,\n", + " 'target': 'ACE2',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '805 / 805, 100.0',\n", + " 'identity': 99.87531172069825,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:62] [15600725:15600911]\n", + " 1 [62:115] [15594844:15595003]\n", + " 2 [115:146] [15592229:15592322]\n", + " 3 [146:194] [15591713:15591857]\n", + " 4 [195:232] [15589343:15589454]\n", + " 5 [232:267] [15587753:15587858]\n", + " 6 [267:299] [15585477:15585573]\n", + " 7 [299:356] [15581222:15581393]\n", + " 8 [356:432] [15578089:15578317]\n", + " 9 [432:481] [15575664:15575811]\n", + " 10 [481:513] [15573368:15573464]\n", + " 11 [513:554] [15572202:15572325]\n", + " 12 [555:612] [15571624:15571795]\n", + " 13 [613:632] [15570294:15570351]\n", + " 14 [632:666] [15567724:15567826]\n", + " 15 [666:704] [15566254:15566368]\n", + " 16 [704:770] [15564022:15564220]\n", + " 17 [770:805] [15561907:15562012]},\n", + " 'urn:mavedb:00000034-b-1': {'chrom': '7',\n", + " 'strand': 1,\n", + " 'target': 'ZRS enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '485 / 486, 99.79423868312757',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:485] [156791118:156791603]},\n", + " 'urn:mavedb:00000049-a-8': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000047-c-1': {'chrom': '3',\n", + " 'strand': 1,\n", + " 'target': 'CCR5',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P51681',\n", + " 'coverage': '1053 / 1053, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:1053] [46372905:46373958]},\n", + " 'urn:mavedb:00000094-a-8': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000041-b-1': {'chrom': '20',\n", + " 'strand': 1,\n", + " 'target': 'Src SH4 domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P12931',\n", + " 'coverage': '54 / 54, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:54] [37384156:37384210]},\n", + " 'urn:mavedb:00000097-o-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 18',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '101 / 101, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:101] [43063302:43063403]},\n", + " 'urn:mavedb:00000045-a-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000097-0-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Locus',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '78414 / 78414, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:78414] [43045704:43124118]},\n", + " 'urn:mavedb:00000097-h-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 5',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '109 / 109, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:109] [43104857:43104966]},\n", + " 'urn:mavedb:00000061-h-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000066-a-1': {'chrom': 'X',\n", + " 'strand': 1,\n", + " 'target': 'GDI1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P31150',\n", + " 'coverage': '1344 / 1344, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:45] [154437254:154437299]\n", + " 1 [45:153] [154438522:154438630]\n", + " 2 [153:253] [154438764:154438864]\n", + " 3 [253:388] [154439005:154439140]\n", + " 4 [388:587] [154439940:154440139]\n", + " 5 [587:719] [154440374:154440506]\n", + " 6 [719:819] [154441095:154441195]\n", + " 7 [819:991] [154441622:154441794]\n", + " 8 [991:1136] [154442110:154442255]\n", + " 9 [1136:1191] [154442373:154442428]\n", + " 10 [1191:1344] [154442519:154442672]},\n", + " 'urn:mavedb:00000021-a-1': {'chrom': '6',\n", + " 'strand': 1,\n", + " 'target': 'IRF4 enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '451 / 451, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:451] [396142:396593]},\n", + " 'urn:mavedb:00000108-a-3': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'HMBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P08397',\n", + " 'coverage': '1086 / 1086, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:33] [119085033:119085066]\n", + " 1 [33:87] [119088254:119088308]\n", + " 2 [87:160] [119088634:119088707]\n", + " 3 [160:210] [119089081:119089131]\n", + " 4 [210:266] [119089216:119089272]\n", + " 5 [266:344] [119089682:119089760]\n", + " 6 [344:422] [119089989:119090067]\n", + " 7 [422:498] [119090189:119090265]\n", + " 8 [498:612] [119091412:119091526]\n", + " 9 [612:651] [119092124:119092163]\n", + " 10 [651:771] [119092403:119092523]\n", + " 11 [771:825] [119092757:119092811]\n", + " 12 [825:912] [119092934:119093021]\n", + " 13 [912:1086] [119093109:119093283]},\n", + " 'urn:mavedb:00000094-a-15': {'chrom': '11',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '676 / 676, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:129] [2445098:2445485]\n", + " 1 [129:159] [2527928:2528018]\n", + " 2 [159:201] [2570627:2570753]\n", + " 3 [201:227] [2571323:2571401]\n", + " 4 [227:260] [2572010:2572109]\n", + " 5 [260:307] [2572845:2572986]\n", + " 6 [307:344] [2583434:2583545]\n", + " 7 [344:375] [2585211:2585304]\n", + " 8 [375:417] [2587566:2587692]\n", + " 9 [417:462] [2588712:2588847]\n", + " 10 [462:505] [2661953:2662082]\n", + " 11 [505:529] [2768844:2768916]\n", + " 12 [529:561] [2775956:2776052]\n", + " 13 [561:577] [2776983:2777031]\n", + " 14 [577:598] [2777974:2778037]\n", + " 15 [598:676] [2847766:2848000]},\n", + " 'urn:mavedb:00000031-a-1': {'chrom': '5',\n", + " 'strand': 1,\n", + " 'target': 'TERT promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '259 / 259, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:259] [1294988:1295247]},\n", + " 'urn:mavedb:00000094-a-2': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000094-a-4': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000059-a-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'p53',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04637',\n", + " 'coverage': '573 / 573, 100.0',\n", + " 'identity': 99.82547993019197,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [479:573] [7673743:7673837]\n", + " 1 [369:479] [7674180:7674290]\n", + " 2 [256:369] [7674858:7674971]\n", + " 3 [72:256] [7675052:7675236]\n", + " 4 [0:72] [7675993:7676065]},\n", + " 'urn:mavedb:00000094-a-1': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000083-i-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - AC-rich enhancer',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '41 / 51, 80.3921568627451',\n", + " 'identity': 97.5609756097561,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [10:51] [32416489:32416530]},\n", + " 'urn:mavedb:00000045-g-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000097-i-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 15',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '106 / 106, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:106] [43070917:43071023]},\n", + " 'urn:mavedb:00000097-w-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 22',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43047617:43047717]},\n", + " 'urn:mavedb:00000045-j-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000103-b-1': {'chrom': '22',\n", + " 'strand': 0,\n", + " 'target': 'MAPK1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '360 / 360, 100.0',\n", + " 'identity': 99.9071494893222,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:39] [21867323:21867440]\n", + " 1 [40:101] [21807662:21807845]\n", + " 2 [101:164] [21805849:21806038]\n", + " 3 [164:203] [21799011:21799128]\n", + " 4 [203:241] [21788694:21788808]\n", + " 5 [241:285] [21788257:21788389]\n", + " 6 [285:322] [21772872:21772983]\n", + " 7 [322:360] [21769206:21769320]},\n", + " 'urn:mavedb:00000097-g-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 5',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '109 / 109, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:109] [43104857:43104966]},\n", + " 'urn:mavedb:00000026-a-1': {'chrom': '8',\n", + " 'strand': 1,\n", + " 'target': 'MYC enhancer (rs11986220)',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '463 / 463, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:463] [127519269:127519732]},\n", + " 'urn:mavedb:00000083-j-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - pyrimidine sequence',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '42 / 51, 82.3529411764706',\n", + " 'identity': 97.61904761904762,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [9:51] [32416489:32416531]},\n", + " 'urn:mavedb:00000049-a-4': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000083-e-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - hnRNP D binding site',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '42 / 51, 82.3529411764706',\n", + " 'identity': 97.61904761904762,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [9:51] [32416489:32416531]},\n", + " 'urn:mavedb:00000014-a-1': {'chrom': '2',\n", + " 'strand': 1,\n", + " 'target': 'BCL11A enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '600 / 600, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:600] [60494939:60495539]},\n", + " 'urn:mavedb:00000097-b-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 2',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '106 / 106, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:106] [43124012:43124118]},\n", + " 'urn:mavedb:00000097-k-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 16',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '108 / 108, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:108] [43067597:43067705]},\n", + " 'urn:mavedb:00000102-0-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'PTEN',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P60484',\n", + " 'coverage': '1212 / 1212, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:79] [87864469:87864548]\n", + " 1 [79:164] [87894024:87894109]\n", + " 2 [164:209] [87925512:87925557]\n", + " 3 [209:253] [87931045:87931089]\n", + " 4 [253:492] [87933012:87933251]\n", + " 5 [492:634] [87952117:87952259]\n", + " 6 [634:801] [87957852:87958019]\n", + " 7 [801:1026] [87960893:87961118]\n", + " 8 [1026:1212] [87965286:87965472]},\n", + " 'urn:mavedb:00000001-b-2': {'chrom': '2',\n", + " 'strand': -1,\n", + " 'target': 'SUMO1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63165',\n", + " 'coverage': '297 / 306, 97.05882352941177',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [237:306] [202207252:202207321]\n", + " 1 [165:237] [202210734:202210806]\n", + " 2 [87:165] [202214356:202214434]\n", + " 3 [9:87] [202220031:202220109]},\n", + " 'urn:mavedb:00000094-a-3': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000061-g-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000001-d-1': {'chrom': '7',\n", + " 'strand': -1,\n", + " 'target': 'TPK1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9H3S4',\n", + " 'coverage': '585 / 585, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [466:585] [144453544:144453663]\n", + " 1 [354:466] [144548490:144548602]\n", + " 2 [258:354] [144623165:144623261]\n", + " 3 [185:258] [144648806:144648879]\n", + " 4 [115:185] [144682908:144682978]\n", + " 5 [43:115] [144765879:144765951]\n", + " 6 [0:43] [144835559:144835602]},\n", + " 'urn:mavedb:00000097-p-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 18',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '101 / 101, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:101] [43063302:43063403]},\n", + " 'urn:mavedb:00000097-x-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 22',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43047617:43047717]},\n", + " 'urn:mavedb:00000055-a-1': {'chrom': '13',\n", + " 'strand': 1,\n", + " 'target': 'NUDT15',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'Q9NV35',\n", + " 'coverage': '495 / 495, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:158] [48037746:48037904]\n", + " 1 [158:355] [48040919:48041116]\n", + " 2 [355:495] [48045659:48045799]},\n", + " 'urn:mavedb:00000094-a-10': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000045-i-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000032-a-1': {'chrom': '2',\n", + " 'strand': 1,\n", + " 'target': 'UC88 enhancer',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '590 / 591, 99.83079526226734',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:590] [161238407:161238997]},\n", + " 'urn:mavedb:00000101-a-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'PTEN',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P60484',\n", + " 'coverage': '1212 / 1212, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:79] [87864469:87864548]\n", + " 1 [79:164] [87894024:87894109]\n", + " 2 [164:209] [87925512:87925557]\n", + " 3 [209:253] [87931045:87931089]\n", + " 4 [253:492] [87933012:87933251]\n", + " 5 [492:634] [87952117:87952259]\n", + " 6 [634:801] [87957852:87958019]\n", + " 7 [801:1026] [87960893:87961118]\n", + " 8 [1026:1212] [87965286:87965472]},\n", + " 'urn:mavedb:00000053-a-1': {'chrom': '17',\n", + " 'strand': 1,\n", + " 'target': 'PSD95 PDZ3',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P78352',\n", + " 'coverage': '249 / 249, 100.0',\n", + " 'identity': 74.6987951807229,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:156] [7196753:7196909]\n", + " 1 [156:249] [7196479:7196572]},\n", + " 'urn:mavedb:00000097-v-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 21',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '105 / 105, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:105] [43049102:43049207]},\n", + " 'urn:mavedb:00000091-a-1': {'chrom': '7',\n", + " 'strand': 0,\n", + " 'target': 'BRAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P15056',\n", + " 'coverage': '118 / 119, 99.15966386554622',\n", + " 'identity': 98.86039886039886,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1:29] [140777992:140778076]\n", + " 1 [29:88] [140776913:140777090]\n", + " 2 [89:105] [140754184:140754232]\n", + " 3 [105:119] [140753349:140753391]},\n", + " 'urn:mavedb:00000048-c-1': {'chrom': '2',\n", + " 'strand': -1,\n", + " 'target': 'CXCR4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P61073',\n", + " 'coverage': '1041 / 1053, 98.86039886039886',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [12:1053] [136114871:136115912]},\n", + " 'urn:mavedb:00000031-c-1': {'chrom': '5',\n", + " 'strand': 1,\n", + " 'target': 'TERT promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '259 / 259, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:259] [1294988:1295247]},\n", + " 'urn:mavedb:00000051-b-1': {'chrom': '17',\n", + " 'strand': 1,\n", + " 'target': 'ErbB2',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04626',\n", + " 'coverage': '71 / 72, 98.61111111111111',\n", + " 'identity': 95.77464788732394,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:71] [39723322:39723393]},\n", + " 'urn:mavedb:00000097-m-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 17',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '98 / 98, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:98] [43063863:43063961]},\n", + " 'urn:mavedb:00000001-b-1': {'chrom': '2',\n", + " 'strand': -1,\n", + " 'target': 'SUMO1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63165',\n", + " 'coverage': '297 / 306, 97.05882352941177',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [237:306] [202207252:202207321]\n", + " 1 [165:237] [202210734:202210806]\n", + " 2 [87:165] [202214356:202214434]\n", + " 3 [9:87] [202220031:202220109]},\n", + " 'urn:mavedb:00000103-a-1': {'chrom': '22',\n", + " 'strand': 0,\n", + " 'target': 'MAPK1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '360 / 360, 100.0',\n", + " 'identity': 99.9071494893222,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:39] [21867323:21867440]\n", + " 1 [40:101] [21807662:21807845]\n", + " 2 [101:164] [21805849:21806038]\n", + " 3 [164:203] [21799011:21799128]\n", + " 4 [203:241] [21788694:21788808]\n", + " 5 [241:285] [21788257:21788389]\n", + " 6 [285:322] [21772872:21772983]\n", + " 7 [322:360] [21769206:21769320]},\n", + " 'urn:mavedb:00000097-f-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43106445:43106545]},\n", + " 'urn:mavedb:00000057-b-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Ras',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P01112',\n", + " 'coverage': '495 / 495, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [447:495] [532707:532755]\n", + " 1 [287:447] [533452:533612]\n", + " 2 [108:287] [533765:533944]\n", + " 3 [0:108] [534211:534319]},\n", + " 'urn:mavedb:00000083-a-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Minigene exon - Wilms’ tumor gene',\n", + " 'target_type': 'Other noncoding',\n", + " 'uniprot': None,\n", + " 'coverage': '51 / 51, 100.0',\n", + " 'identity': 98.0392156862745,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:51] [32416489:32416540]},\n", + " 'urn:mavedb:00000097-s-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 20',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43051039:43051139]},\n", + " 'urn:mavedb:00000024-a-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'MSMB promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '591 / 591, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:591] [46046243:46046834]},\n", + " 'urn:mavedb:00000045-f-1': {'chrom': '4',\n", + " 'strand': -1,\n", + " 'target': 'alpha-synuclein',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P37840',\n", + " 'coverage': '423 / 423, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [390:423] [89726627:89726660]\n", + " 1 [306:390] [89729193:89729277]\n", + " 2 [163:306] [89822245:89822388]\n", + " 3 [121:163] [89828142:89828184]\n", + " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000072-a-1': {'chrom': '14',\n", + " 'strand': 0,\n", + " 'target': 'IGHG1',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P01857',\n", + " 'coverage': '106 / 106, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:106] [105741478:105741796]},\n", + " 'urn:mavedb:00000095-b-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'CYP2C9',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P11712',\n", + " 'coverage': '1470 / 1470, 100.0',\n", + " 'identity': 99.1991991991992,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:168] [94938682:94938850]\n", + " 1 [168:331] [94941857:94942020]\n", + " 2 [331:481] [94942191:94942341]\n", + " 3 [481:536] [94947778:94947833]\n", + " 4 [937:959] [94972221:94972243]\n", + " 5 [1029:1149] [94981250:94981370]\n", + " 6 [1149:1291] [94986032:94986174]\n", + " 7 [1291:1470] [94988846:94989025]},\n", + " 'urn:mavedb:00000001-a-1': {'chrom': '16',\n", + " 'strand': 1,\n", + " 'target': 'UBE2I',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63279',\n", + " 'coverage': '477 / 477, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:66] [1314030:1314096]\n", + " 1 [66:150] [1314292:1314376]\n", + " 2 [150:223] [1315653:1315726]\n", + " 3 [223:333] [1320173:1320283]\n", + " 4 [333:413] [1320437:1320517]\n", + " 5 [413:477] [1324729:1324793]},\n", + " 'urn:mavedb:00000023-a-1': {'chrom': '19',\n", + " 'strand': 1,\n", + " 'target': 'LDLR promoter',\n", + " 'target_type': 'Regulatory',\n", + " 'uniprot': None,\n", + " 'coverage': '318 / 318, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:318] [11089230:11089548]},\n", + " 'urn:mavedb:00000049-a-2': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'MTHFR',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P42898',\n", + " 'coverage': '1971 / 1971, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [1752:1971] [11790679:11790898]\n", + " 1 [1632:1752] [11791206:11791326]\n", + " 2 [1530:1632] [11792277:11792379]\n", + " 3 [1347:1530] [11793906:11794089]\n", + " 4 [1166:1347] [11794357:11794538]\n", + " 5 [1031:1166] [11794728:11794863]\n", + " 6 [780:1031] [11795097:11795348]\n", + " 7 [586:780] [11796205:11796399]\n", + " 8 [475:586] [11800211:11800322]\n", + " 9 [236:475] [11801160:11801399]\n", + " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000062-b-1': {'chrom': '10',\n", + " 'strand': 1,\n", + " 'target': 'CYP2C19',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P33261',\n", + " 'coverage': '1443 / 1443, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:144] [94762729:94762873]\n", + " 1 [144:307] [94775057:94775220]\n", + " 2 [307:457] [94775389:94775539]\n", + " 3 [457:618] [94780498:94780659]\n", + " 4 [618:795] [94781820:94781997]\n", + " 5 [795:937] [94820495:94820637]\n", + " 6 [937:1125] [94842836:94843024]\n", + " 7 [1125:1267] [94849916:94850058]\n", + " 8 [1267:1443] [94852732:94852908]},\n", + " 'urn:mavedb:00000094-a-12': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000057-c-1': {'chrom': '11',\n", + " 'strand': -1,\n", + " 'target': 'Ras',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P01112',\n", + " 'coverage': '495 / 495, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [447:495] [532707:532755]\n", + " 1 [287:447] [533452:533612]\n", + " 2 [108:287] [533765:533944]\n", + " 3 [0:108] [534211:534319]},\n", + " 'urn:mavedb:00000094-a-7': {'chrom': '1',\n", + " 'strand': 0,\n", + " 'target': 'KCNQ4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '695 / 695, 100.0',\n", + " 'identity': 99.9519692603266,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [40784093:40784405]\n", + " 1 [105:135] [40817265:40817355]\n", + " 2 [135:177] [40818163:40818289]\n", + " 3 [177:236] [40818503:40818680]\n", + " 4 [236:278] [40819346:40819472]\n", + " 5 [278:315] [40819874:40819985]\n", + " 6 [315:346] [40820164:40820257]\n", + " 7 [346:376] [40822310:40822400]\n", + " 8 [376:430] [40824094:40824256]\n", + " 9 [430:504] [40831081:40831303]\n", + " 10 [504:537] [40833012:40833111]\n", + " 11 [537:581] [40834964:40835096]\n", + " 12 [581:624] [40837662:40837791]\n", + " 13 [624:695] [40838307:40838520]},\n", + " 'urn:mavedb:00000061-f-1': {'chrom': '3',\n", + " 'strand': -1,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", + " 'urn:mavedb:00000001-a-2': {'chrom': '16',\n", + " 'strand': 1,\n", + " 'target': 'UBE2I',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P63279',\n", + " 'coverage': '477 / 477, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:66] [1314030:1314096]\n", + " 1 [66:150] [1314292:1314376]\n", + " 2 [150:223] [1315653:1315726]\n", + " 3 [223:333] [1320173:1320283]\n", + " 4 [333:413] [1320437:1320517]\n", + " 5 [413:477] [1324729:1324793]},\n", " 'urn:mavedb:00000083-d-1': {'chrom': '11',\n", " 'strand': -1,\n", " 'target': 'Minigene exon - hnRNPA1 binding site',\n", @@ -1818,16 +3643,6 @@ " 'identity': 97.61904761904762,\n", " 'hits': query_ranges hit_ranges\n", " 0 [9:51] [32416489:32416531]},\n", - " 'urn:mavedb:00000061-i-1': {'chrom': '3',\n", - " 'strand': -1,\n", - " 'target': 'RAF',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P04049',\n", - " 'coverage': '117 / 117, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [54:117] [12611999:12612062]\n", - " 1 [0:54] [12618514:12618568]},\n", " 'urn:mavedb:00000003-b-2': {'chrom': '17',\n", " 'strand': -1,\n", " 'target': 'BRCA1 RING domain',\n", @@ -1871,6 +3686,15 @@ " 6 [955:1143] [94981182:94981370]\n", " 7 [1143:1285] [94986032:94986174]\n", " 8 [1285:1461] [94988846:94989022]},\n", + " 'urn:mavedb:00000097-e-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 4',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43106445:43106545]},\n", " 'urn:mavedb:00000005-a-5': {'chrom': '21',\n", " 'strand': -1,\n", " 'target': 'CBS',\n", @@ -1903,15 +3727,6 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:579] [37807498:37808077]},\n", - " 'urn:mavedb:00000083-b-1': {'chrom': '11',\n", - " 'strand': -1,\n", - " 'target': 'Minigene exon - SRSF1 (ASF/SF2) binding site',\n", - " 'target_type': 'Other noncoding',\n", - " 'uniprot': None,\n", - " 'coverage': '41 / 51, 80.3921568627451',\n", - " 'identity': 97.5609756097561,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [10:51] [32416489:32416530]},\n", " 'urn:mavedb:00000057-d-1': {'chrom': '11',\n", " 'strand': -1,\n", " 'target': 'Ras',\n", @@ -1924,28 +3739,6 @@ " 1 [287:447] [533452:533612]\n", " 2 [108:287] [533765:533944]\n", " 3 [0:108] [534211:534319]},\n", - " 'urn:mavedb:00000094-a-5': {'chrom': '1',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '695 / 695, 100.0',\n", - " 'identity': 99.9519692603266,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:104] [40784093:40784405]\n", - " 1 [105:135] [40817265:40817355]\n", - " 2 [135:177] [40818163:40818289]\n", - " 3 [177:236] [40818503:40818680]\n", - " 4 [236:278] [40819346:40819472]\n", - " 5 [278:315] [40819874:40819985]\n", - " 6 [315:346] [40820164:40820257]\n", - " 7 [346:376] [40822310:40822400]\n", - " 8 [376:430] [40824094:40824256]\n", - " 9 [430:504] [40831081:40831303]\n", - " 10 [504:537] [40833012:40833111]\n", - " 11 [537:581] [40834964:40835096]\n", - " 12 [581:624] [40837662:40837791]\n", - " 13 [624:695] [40838307:40838520]},\n", " 'urn:mavedb:00000068-a-1': {'chrom': '17',\n", " 'strand': -1,\n", " 'target': 'TP53 (P72R)',\n", @@ -1983,27 +3776,37 @@ " 8 [475:586] [11800211:11800322]\n", " 9 [236:475] [11801160:11801399]\n", " 10 [0:236] [11802880:11803116]},\n", - " 'urn:mavedb:00000043-a-2': {'chrom': '1',\n", - " 'strand': 1,\n", - " 'target': 'S505N MPL',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P40238',\n", - " 'coverage': '93 / 93, 100.0',\n", - " 'identity': 98.9247311827957,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:10] [43348992:43349002]\n", - " 1 [10:93] [43349262:43349345]},\n", - " 'urn:mavedb:00000055-0-1': {'chrom': '13',\n", - " 'strand': 1,\n", - " 'target': 'NUDT15',\n", + " 'urn:mavedb:00000104-a-1': {'chrom': '1',\n", + " 'strand': -1,\n", + " 'target': 'PARP1',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'Q9NV35',\n", - " 'coverage': '495 / 495, 100.0',\n", + " 'uniprot': None,\n", + " 'coverage': '3958 / 3958, 100.0',\n", " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:158] [48037746:48037904]\n", - " 1 [158:355] [48040919:48041116]\n", - " 2 [355:495] [48045659:48045799]},\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [3107:3958] [226360690:226361541]\n", + " 1 [2992:3107] [226361968:226362083]\n", + " 2 [2930:2992] [226363098:226363160]\n", + " 3 [2802:2930] [226363942:226364070]\n", + " 4 [2649:2802] [226365001:226365154]\n", + " 5 [2550:2649] [226365953:226366052]\n", + " 6 [2421:2550] [226367479:226367608]\n", + " 7 [2298:2421] [226368198:226368321]\n", + " 8 [2214:2298] [226370433:226370517]\n", + " 9 [2085:2214] [226374225:226374354]\n", + " 10 [1889:2085] [226377107:226377303]\n", + " 11 [1756:1889] [226379141:226379274]\n", + " 12 [1687:1756] [226379572:226379641]\n", + " 13 [1444:1687] [226379921:226380164]\n", + " 14 [1303:1444] [226381067:226381208]\n", + " 15 [1155:1303] [226383035:226383183]\n", + " 16 [978:1155] [226385503:226385680]\n", + " 17 [861:978] [226386325:226386442]\n", + " 18 [761:861] [226388655:226388755]\n", + " 19 [546:761] [226390409:226390624]\n", + " 20 [430:546] [226392198:226392314]\n", + " 21 [264:430] [226402213:226402379]\n", + " 22 [0:264] [226407809:226408073]},\n", " 'urn:mavedb:00000083-c-1': {'chrom': '11',\n", " 'strand': -1,\n", " 'target': 'Minigene exon - SRSF7 (9G8) binding site',\n", @@ -2013,38 +3816,6 @@ " 'identity': 97.5609756097561,\n", " 'hits': query_ranges hit_ranges\n", " 0 [10:51] [32416489:32416530]},\n", - " 'urn:mavedb:00000005-a-6': {'chrom': '21',\n", - " 'strand': -1,\n", - " 'target': 'CBS',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P35520',\n", - " 'coverage': '1656 / 1656, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [1552:1656] [43053879:43053983]\n", - " 1 [1467:1552] [43056802:43056887]\n", - " 2 [1358:1467] [43058144:43058253]\n", - " 3 [1223:1358] [43058833:43058968]\n", - " 4 [1145:1223] [43059225:43059303]\n", - " 5 [1039:1145] [43060440:43060546]\n", - " 6 [954:1039] [43062310:43062395]\n", - " 7 [828:954] [43062952:43063078]\n", - " 8 [736:828] [43063899:43063991]\n", - " 9 [666:736] [43065202:43065272]\n", - " 10 [531:666] [43065386:43065521]\n", - " 11 [451:531] [43065615:43065695]\n", - " 12 [316:451] [43066242:43066377]\n", - " 13 [209:316] [43068508:43068615]\n", - " 14 [0:209] [43071984:43072193]},\n", - " 'urn:mavedb:00000083-h-1': {'chrom': '11',\n", - " 'strand': -1,\n", - " 'target': 'Minigene exon - CG-containing enhancer',\n", - " 'target_type': 'Other noncoding',\n", - " 'uniprot': None,\n", - " 'coverage': '41 / 51, 80.3921568627451',\n", - " 'identity': 97.5609756097561,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [10:51] [32416489:32416530]},\n", " 'urn:mavedb:00000049-a-1': {'chrom': '1',\n", " 'strand': -1,\n", " 'target': 'MTHFR',\n", @@ -2073,42 +3844,6 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:600] [43086478:43087078]},\n", - " 'urn:mavedb:00000001-a-4': {'chrom': '16',\n", - " 'strand': 1,\n", - " 'target': 'UBE2I',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P63279',\n", - " 'coverage': '477 / 477, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:66] [1314030:1314096]\n", - " 1 [66:150] [1314292:1314376]\n", - " 2 [150:223] [1315653:1315726]\n", - " 3 [223:333] [1320173:1320283]\n", - " 4 [333:413] [1320437:1320517]\n", - " 5 [413:477] [1324729:1324793]},\n", - " 'urn:mavedb:00000094-a-6': {'chrom': '1',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '695 / 695, 100.0',\n", - " 'identity': 99.9519692603266,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:104] [40784093:40784405]\n", - " 1 [105:135] [40817265:40817355]\n", - " 2 [135:177] [40818163:40818289]\n", - " 3 [177:236] [40818503:40818680]\n", - " 4 [236:278] [40819346:40819472]\n", - " 5 [278:315] [40819874:40819985]\n", - " 6 [315:346] [40820164:40820257]\n", - " 7 [346:376] [40822310:40822400]\n", - " 8 [376:430] [40824094:40824256]\n", - " 9 [430:504] [40831081:40831303]\n", - " 10 [504:537] [40833012:40833111]\n", - " 11 [537:581] [40834964:40835096]\n", - " 12 [581:624] [40837662:40837791]\n", - " 13 [624:695] [40838307:40838520]},\n", " 'urn:mavedb:00000029-a-1': {'chrom': '1',\n", " 'strand': 1,\n", " 'target': 'SORT1 enhancer',\n", @@ -2118,151 +3853,48 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:600] [109274651:109275251]},\n", - " 'urn:mavedb:00000078-a-1': {'chrom': '16',\n", - " 'strand': 0,\n", - " 'target': 'VKOR',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '163 / 163, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:57] [31094558:31094729]\n", - " 1 [57:94] [31093312:31093423]\n", - " 2 [94:163] [31091136:31091343]},\n", " 'urn:mavedb:00000013-b-1': {'chrom': '6',\n", " 'strand': -1,\n", - " 'target': 'TPMT',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P51580',\n", - " 'coverage': '738 / 738, 100.0',\n", - " 'identity': 99.86449864498645,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [625:738] [18130667:18130780]\n", - " 1 [580:625] [18132132:18132177]\n", - " 2 [494:580] [18133803:18133889]\n", - " 3 [419:494] [18138962:18139037]\n", - " 4 [366:419] [18139664:18139717]\n", - " 5 [233:366] [18143595:18143728]\n", - " 6 [140:233] [18147822:18147915]\n", - " 7 [0:140] [18148987:18149127]},\n", - " 'urn:mavedb:00000043-a-1': {'chrom': '1',\n", - " 'strand': 1,\n", - " 'target': 'MPL',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P40238',\n", - " 'coverage': '93 / 93, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:10] [43348992:43349002]\n", - " 1 [10:93] [43349262:43349345]},\n", - " 'urn:mavedb:00000093-a-1': {'chrom': '17',\n", - " 'strand': -1,\n", - " 'target': 'BRCA1 translation start through RING domain',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P38398',\n", - " 'coverage': '300 / 300, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [212:300] [43104868:43104956]\n", - " 1 [134:212] [43106455:43106533]\n", - " 2 [80:134] [43115725:43115779]\n", - " 3 [0:80] [43124016:43124096]},\n", - " 'urn:mavedb:00000061-d-1': {'chrom': '3',\n", - " 'strand': -1,\n", - " 'target': 'RAF',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P04049',\n", - " 'coverage': '117 / 117, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [54:117] [12611999:12612062]\n", - " 1 [0:54] [12618514:12618568]},\n", - " 'urn:mavedb:00000001-a-3': {'chrom': '16',\n", - " 'strand': 1,\n", - " 'target': 'UBE2I',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P63279',\n", - " 'coverage': '477 / 477, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:66] [1314030:1314096]\n", - " 1 [66:150] [1314292:1314376]\n", - " 2 [150:223] [1315653:1315726]\n", - " 3 [223:333] [1320173:1320283]\n", - " 4 [333:413] [1320437:1320517]\n", - " 5 [413:477] [1324729:1324793]},\n", - " 'urn:mavedb:00000046-a-1': {'chrom': '3',\n", - " 'strand': 1,\n", - " 'target': 'CD86',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P42081',\n", - " 'coverage': '81 / 81, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:81] [122109290:122109371]},\n", - " 'urn:mavedb:00000081-a-1': {'chrom': '17',\n", - " 'strand': 0,\n", - " 'target': 'BRCA1',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P38398',\n", - " 'coverage': '1863 / 1863, 100.0',\n", - " 'identity': 99.94623655913979,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:26] [43124018:43124096]\n", - " 1 [27:45] [43115724:43115778]\n", - " 2 [45:70] [43106457:43106532]\n", - " 3 [70:100] [43104868:43104958]\n", - " 4 [101:147] [43104121:43104259]\n", - " 5 [147:181] [43099778:43099880]\n", - " 6 [181:197] [43097245:43097293]\n", - " 7 [197:223] [43095846:43095924]\n", - " 8 [223:1365] [43091435:43094861]\n", - " 9 [1365:1395] [43090943:43091033]\n", - " 10 [1395:1451] [43082407:43082575]\n", - " 11 [1451:1494] [43076489:43076618]\n", - " 12 [1494:1558] [43074331:43074523]\n", - " 13 [1558:1662] [43070927:43071239]\n", - " 14 [1662:1691] [43067608:43067695]\n", - " 15 [1691:1717] [43063874:43063952]\n", - " 16 [1718:1731] [43063332:43063371]\n", - " 17 [1731:1759] [43057051:43057135]\n", - " 18 [1759:1777] [43051063:43051117]\n", - " 19 [1777:1802] [43049120:43049195]\n", - " 20 [1802:1822] [43047643:43047703]\n", - " 21 [1822:1863] [43045680:43045803]},\n", - " 'urn:mavedb:00000067-a-1': {'chrom': '19',\n", - " 'strand': 1,\n", - " 'target': 'TECR',\n", + " 'target': 'TPMT',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'Q9NZ01',\n", - " 'coverage': '916 / 927, 98.8133764832794',\n", + " 'uniprot': 'P51580',\n", + " 'coverage': '738 / 738, 100.0',\n", + " 'identity': 99.86449864498645,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [625:738] [18130667:18130780]\n", + " 1 [580:625] [18132132:18132177]\n", + " 2 [494:580] [18133803:18133889]\n", + " 3 [419:494] [18138962:18139037]\n", + " 4 [366:419] [18139664:18139717]\n", + " 5 [233:366] [18143595:18143728]\n", + " 6 [140:233] [18147822:18147915]\n", + " 7 [0:140] [18148987:18149127]},\n", + " 'urn:mavedb:00000093-a-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 translation start through RING domain',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P38398',\n", + " 'coverage': '300 / 300, 100.0',\n", " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [11:66] [14562520:14562575]\n", - " 1 [66:118] [14563205:14563257]\n", - " 2 [118:163] [14563657:14563702]\n", - " 3 [163:267] [14563799:14563903]\n", - " 4 [267:383] [14563981:14564097]\n", - " 5 [383:489] [14564181:14564287]\n", - " 6 [489:562] [14564785:14564858]\n", - " 7 [562:606] [14564948:14564992]\n", - " 8 [606:664] [14565065:14565123]\n", - " 9 [664:753] [14565201:14565290]\n", - " 10 [753:799] [14565617:14565663]\n", - " 11 [799:927] [14565743:14565871]},\n", - " 'urn:mavedb:00000001-c-2': {'chrom': '14',\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [212:300] [43104868:43104956]\n", + " 1 [134:212] [43106455:43106533]\n", + " 2 [80:134] [43115725:43115779]\n", + " 3 [0:80] [43124016:43124096]},\n", + " 'urn:mavedb:00000001-a-3': {'chrom': '16',\n", " 'strand': 1,\n", - " 'target': 'CALM1',\n", + " 'target': 'UBE2I',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P0DP23',\n", - " 'coverage': '448 / 450, 99.55555555555556',\n", + " 'uniprot': 'P63279',\n", + " 'coverage': '477 / 477, 100.0',\n", " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [2:34] [90400063:90400095]\n", - " 1 [34:178] [90401258:90401402]\n", - " 2 [178:285] [90403861:90403968]\n", - " 3 [285:421] [90404378:90404514]\n", - " 4 [421:450] [90404688:90404717]},\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:66] [1314030:1314096]\n", + " 1 [66:150] [1314292:1314376]\n", + " 2 [150:223] [1315653:1315726]\n", + " 3 [223:333] [1320173:1320283]\n", + " 4 [333:413] [1320437:1320517]\n", + " 5 [413:477] [1324729:1324793]},\n", " 'urn:mavedb:00000045-d-1': {'chrom': '4',\n", " 'strand': -1,\n", " 'target': 'alpha-synuclein',\n", @@ -2276,6 +3908,28 @@ " 2 [163:306] [89822245:89822388]\n", " 3 [121:163] [89828142:89828184]\n", " 4 [0:121] [89835546:89835667]},\n", + " 'urn:mavedb:00000108-a-1': {'chrom': '11',\n", + " 'strand': 1,\n", + " 'target': 'HMBS',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P08397',\n", + " 'coverage': '1086 / 1086, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:33] [119085033:119085066]\n", + " 1 [33:87] [119088254:119088308]\n", + " 2 [87:160] [119088634:119088707]\n", + " 3 [160:210] [119089081:119089131]\n", + " 4 [210:266] [119089216:119089272]\n", + " 5 [266:344] [119089682:119089760]\n", + " 6 [344:422] [119089989:119090067]\n", + " 7 [422:498] [119090189:119090265]\n", + " 8 [498:612] [119091412:119091526]\n", + " 9 [612:651] [119092124:119092163]\n", + " 10 [651:771] [119092403:119092523]\n", + " 11 [771:825] [119092757:119092811]\n", + " 12 [825:912] [119092934:119093021]\n", + " 13 [912:1086] [119093109:119093283]},\n", " 'urn:mavedb:00000096-a-1': {'chrom': '7',\n", " 'strand': 1,\n", " 'target': 'GCK',\n", @@ -2311,61 +3965,27 @@ " 6 [131:209] [43106455:43106533]\n", " 7 [78:131] [43115725:43115778]\n", " 8 [0:77] [43124016:43124093]},\n", - " 'urn:mavedb:00000049-a-7': {'chrom': '1',\n", - " 'strand': -1,\n", - " 'target': 'MTHFR',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P42898',\n", - " 'coverage': '1971 / 1971, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [1752:1971] [11790679:11790898]\n", - " 1 [1632:1752] [11791206:11791326]\n", - " 2 [1530:1632] [11792277:11792379]\n", - " 3 [1347:1530] [11793906:11794089]\n", - " 4 [1166:1347] [11794357:11794538]\n", - " 5 [1031:1166] [11794728:11794863]\n", - " 6 [780:1031] [11795097:11795348]\n", - " 7 [586:780] [11796205:11796399]\n", - " 8 [475:586] [11800211:11800322]\n", - " 9 [236:475] [11801160:11801399]\n", - " 10 [0:236] [11802880:11803116]},\n", - " 'urn:mavedb:00000060-a-2': {'chrom': '1',\n", - " 'strand': 1,\n", - " 'target': 'TARDBP',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'Q13148',\n", - " 'coverage': '1242 / 1242, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:238] [11013727:11013965]\n", - " 1 [238:402] [11016843:11017007]\n", - " 2 [402:543] [11018732:11018873]\n", - " 3 [543:714] [11020428:11020599]\n", - " 4 [714:1242] [11022123:11022651]},\n", - " 'urn:mavedb:00000058-a-1': {'chrom': '21',\n", + " 'urn:mavedb:00000097-c-1': {'chrom': '17',\n", " 'strand': -1,\n", - " 'target': 'Aβ42',\n", + " 'target': 'BRCA1 Exon 3',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P05067',\n", - " 'coverage': '126 / 126, 100.0',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", - " 0 [51:126] [25891793:25891868]\n", - " 1 [0:51] [25897572:25897623]},\n", - " 'urn:mavedb:00000045-k-1': {'chrom': '4',\n", - " 'strand': -1,\n", - " 'target': 'alpha-synuclein',\n", + " 0 [0:100] [43115702:43115802]},\n", + " 'urn:mavedb:00000106-a-1': {'chrom': '12',\n", + " 'strand': 0,\n", + " 'target': 'AID',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P37840',\n", - " 'coverage': '423 / 423, 100.0',\n", + " 'uniprot': None,\n", + " 'coverage': '196 / 198, 98.98989898989899',\n", " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [390:423] [89726627:89726660]\n", - " 1 [306:390] [89729193:89729277]\n", - " 2 [163:306] [89822245:89822388]\n", - " 3 [121:163] [89828142:89828184]\n", - " 4 [0:121] [89835546:89835667]},\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [2:52] [8606864:8607014]\n", + " 1 [52:142] [8605215:8605485]\n", + " 2 [142:181] [8604806:8604923]\n", + " 3 [181:198] [8604286:8604337]},\n", " 'urn:mavedb:00000083-g-1': {'chrom': '11',\n", " 'strand': -1,\n", " 'target': 'Minigene exon - hnRNP L binding site',\n", @@ -2375,30 +3995,6 @@ " 'identity': 97.5609756097561,\n", " 'hits': query_ranges hit_ranges\n", " 0 [10:51] [32416489:32416530]},\n", - " 'urn:mavedb:00000094-a-14': {'chrom': '11',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ1',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '676 / 676, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:129] [2445098:2445485]\n", - " 1 [129:159] [2527928:2528018]\n", - " 2 [159:201] [2570627:2570753]\n", - " 3 [201:227] [2571323:2571401]\n", - " 4 [227:260] [2572010:2572109]\n", - " 5 [260:307] [2572845:2572986]\n", - " 6 [307:344] [2583434:2583545]\n", - " 7 [344:375] [2585211:2585304]\n", - " 8 [375:417] [2587566:2587692]\n", - " 9 [417:462] [2588712:2588847]\n", - " 10 [462:505] [2661953:2662082]\n", - " 11 [505:529] [2768844:2768916]\n", - " 12 [529:561] [2775956:2776052]\n", - " 13 [561:577] [2776983:2777031]\n", - " 14 [577:598] [2777974:2778037]\n", - " 15 [598:676] [2847766:2848000]},\n", " 'urn:mavedb:00000036-a-2': {'chrom': '1',\n", " 'strand': 1,\n", " 'target': 'LDLRAP1',\n", @@ -2416,6 +4012,24 @@ " 6 [616:747] [25563660:25563791]\n", " 7 [747:782] [25565172:25565207]\n", " 8 [782:927] [25566847:25566992]},\n", + " 'urn:mavedb:00000097-t-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 20',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43051039:43051139]},\n", + " 'urn:mavedb:00000097-l-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 16',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '108 / 108, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:108] [43067597:43067705]},\n", " 'urn:mavedb:00000094-a-11': {'chrom': '1',\n", " 'strand': 0,\n", " 'target': 'KCNQ4',\n", @@ -2447,32 +4061,6 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:470] [155301394:155301864]},\n", - " 'urn:mavedb:00000069-a-2': {'chrom': 'X',\n", - " 'strand': 0,\n", - " 'target': 'ACE2',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'Q9BYF1',\n", - " 'coverage': '805 / 805, 100.0',\n", - " 'identity': 99.87531172069825,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:62] [15600725:15600911]\n", - " 1 [62:115] [15594844:15595003]\n", - " 2 [115:146] [15592229:15592322]\n", - " 3 [146:194] [15591713:15591857]\n", - " 4 [195:232] [15589343:15589454]\n", - " 5 [232:267] [15587753:15587858]\n", - " 6 [267:299] [15585477:15585573]\n", - " 7 [299:356] [15581222:15581393]\n", - " 8 [356:432] [15578089:15578317]\n", - " 9 [432:481] [15575664:15575811]\n", - " 10 [481:513] [15573368:15573464]\n", - " 11 [513:554] [15572202:15572325]\n", - " 12 [555:612] [15571624:15571795]\n", - " 13 [613:632] [15570294:15570351]\n", - " 14 [632:666] [15567724:15567826]\n", - " 15 [666:704] [15566254:15566368]\n", - " 16 [704:770] [15564022:15564220]\n", - " 17 [770:805] [15561907:15562012]},\n", " 'urn:mavedb:00000002-a-2': {'chrom': '11',\n", " 'strand': 1,\n", " 'target': 'hYAP65 WW domain',\n", @@ -2529,15 +4117,6 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:259] [1294988:1295247]},\n", - " 'urn:mavedb:00000046-a-2': {'chrom': '3',\n", - " 'strand': 1,\n", - " 'target': 'CD86',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P42081',\n", - " 'coverage': '81 / 81, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:81] [122109290:122109371]},\n", " 'urn:mavedb:00000035-a-3': {'chrom': '5',\n", " 'strand': 1,\n", " 'target': 'HMGCR',\n", @@ -2574,32 +4153,6 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:259] [101433287:101433546]},\n", - " 'urn:mavedb:00000069-a-1': {'chrom': 'X',\n", - " 'strand': 0,\n", - " 'target': 'ACE2',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '805 / 805, 100.0',\n", - " 'identity': 99.87531172069825,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:62] [15600725:15600911]\n", - " 1 [62:115] [15594844:15595003]\n", - " 2 [115:146] [15592229:15592322]\n", - " 3 [146:194] [15591713:15591857]\n", - " 4 [195:232] [15589343:15589454]\n", - " 5 [232:267] [15587753:15587858]\n", - " 6 [267:299] [15585477:15585573]\n", - " 7 [299:356] [15581222:15581393]\n", - " 8 [356:432] [15578089:15578317]\n", - " 9 [432:481] [15575664:15575811]\n", - " 10 [481:513] [15573368:15573464]\n", - " 11 [513:554] [15572202:15572325]\n", - " 12 [555:612] [15571624:15571795]\n", - " 13 [613:632] [15570294:15570351]\n", - " 14 [632:666] [15567724:15567826]\n", - " 15 [666:704] [15566254:15566368]\n", - " 16 [704:770] [15564022:15564220]\n", - " 17 [770:805] [15561907:15562012]},\n", " 'urn:mavedb:00000094-a-13': {'chrom': '1',\n", " 'strand': 0,\n", " 'target': 'KCNQ4',\n", @@ -2644,91 +4197,81 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:44] [144116887:144116931]},\n", - " 'urn:mavedb:00000036-a-1': {'chrom': '1',\n", - " 'strand': 1,\n", - " 'target': 'LDLRAP1',\n", + " 'urn:mavedb:00000097-u-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 21',\n", " 'target_type': 'Protein coding',\n", " 'uniprot': None,\n", - " 'coverage': '927 / 927, 100.0',\n", - " 'identity': 99.78425026968716,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:88] [25543698:25543786]\n", - " 1 [88:231] [25553921:25554064]\n", - " 2 [231:344] [25554859:25554972]\n", - " 3 [344:459] [25557152:25557267]\n", - " 4 [459:532] [25562643:25562716]\n", - " 5 [532:616] [25563069:25563153]\n", - " 6 [616:747] [25563660:25563791]\n", - " 7 [747:782] [25565172:25565207]\n", - " 8 [782:927] [25566847:25566992]},\n", - " 'urn:mavedb:00000034-b-1': {'chrom': '7',\n", - " 'strand': 1,\n", - " 'target': 'ZRS enhancer',\n", - " 'target_type': 'Regulatory',\n", - " 'uniprot': None,\n", - " 'coverage': '485 / 486, 99.79423868312757',\n", + " 'coverage': '105 / 105, 100.0',\n", " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:485] [156791118:156791603]},\n", - " 'urn:mavedb:00000049-a-8': {'chrom': '1',\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:105] [43049102:43049207]},\n", + " 'urn:mavedb:00000097-d-1': {'chrom': '17',\n", " 'strand': -1,\n", - " 'target': 'MTHFR',\n", + " 'target': 'BRCA1 Exon 3',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P42898',\n", - " 'coverage': '1971 / 1971, 100.0',\n", + " 'uniprot': None,\n", + " 'coverage': '100 / 100, 100.0',\n", " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [1752:1971] [11790679:11790898]\n", - " 1 [1632:1752] [11791206:11791326]\n", - " 2 [1530:1632] [11792277:11792379]\n", - " 3 [1347:1530] [11793906:11794089]\n", - " 4 [1166:1347] [11794357:11794538]\n", - " 5 [1031:1166] [11794728:11794863]\n", - " 6 [780:1031] [11795097:11795348]\n", - " 7 [586:780] [11796205:11796399]\n", - " 8 [475:586] [11800211:11800322]\n", - " 9 [236:475] [11801160:11801399]\n", - " 10 [0:236] [11802880:11803116]},\n", - " 'urn:mavedb:00000047-c-1': {'chrom': '3',\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:100] [43115702:43115802]},\n", + " 'urn:mavedb:00000036-a-1': {'chrom': '1',\n", " 'strand': 1,\n", - " 'target': 'CCR5',\n", + " 'target': 'LDLRAP1',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P51681',\n", - " 'coverage': '1053 / 1053, 100.0',\n", - " 'identity': 100.0,\n", + " 'uniprot': None,\n", + " 'coverage': '927 / 927, 100.0',\n", + " 'identity': 99.78425026968716,\n", " 'hits': query_ranges hit_ranges\n", - " 0 [0:1053] [46372905:46373958]},\n", - " 'urn:mavedb:00000094-a-8': {'chrom': '1',\n", + " 0 [0:88] [25543698:25543786]\n", + " 1 [88:231] [25553921:25554064]\n", + " 2 [231:344] [25554859:25554972]\n", + " 3 [344:459] [25557152:25557267]\n", + " 4 [459:532] [25562643:25562716]\n", + " 5 [532:616] [25563069:25563153]\n", + " 6 [616:747] [25563660:25563791]\n", + " 7 [747:782] [25565172:25565207]\n", + " 8 [782:927] [25566847:25566992]},\n", + " 'urn:mavedb:00000105-a-1': {'chrom': 'NA',\n", + " 'strand': 'NA',\n", + " 'target': 'NA',\n", + " 'target_type': 'NA',\n", + " 'uniprot': 'NA',\n", + " 'coverage': 'NA',\n", + " 'identity': 'NA',\n", + " 'hits': query_ranges hit_ranges\n", + " 0 N N\n", + " 1 A A},\n", + " 'urn:mavedb:00000081-a-2': {'chrom': '17',\n", " 'strand': 0,\n", - " 'target': 'KCNQ4',\n", + " 'target': 'BRCA1',\n", " 'target_type': 'Protein coding',\n", " 'uniprot': None,\n", - " 'coverage': '695 / 695, 100.0',\n", - " 'identity': 99.9519692603266,\n", + " 'coverage': '1863 / 1863, 100.0',\n", + " 'identity': 99.94623655913979,\n", " 'hits': query_ranges hit_ranges\n", - " 0 [0:104] [40784093:40784405]\n", - " 1 [105:135] [40817265:40817355]\n", - " 2 [135:177] [40818163:40818289]\n", - " 3 [177:236] [40818503:40818680]\n", - " 4 [236:278] [40819346:40819472]\n", - " 5 [278:315] [40819874:40819985]\n", - " 6 [315:346] [40820164:40820257]\n", - " 7 [346:376] [40822310:40822400]\n", - " 8 [376:430] [40824094:40824256]\n", - " 9 [430:504] [40831081:40831303]\n", - " 10 [504:537] [40833012:40833111]\n", - " 11 [537:581] [40834964:40835096]\n", - " 12 [581:624] [40837662:40837791]\n", - " 13 [624:695] [40838307:40838520]},\n", - " 'urn:mavedb:00000041-b-1': {'chrom': '20',\n", - " 'strand': 1,\n", - " 'target': 'Src SH4 domain',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P12931',\n", - " 'coverage': '54 / 54, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:54] [37384156:37384210]},\n", + " 0 [0:26] [43124018:43124096]\n", + " 1 [27:45] [43115724:43115778]\n", + " 2 [45:70] [43106457:43106532]\n", + " 3 [70:100] [43104868:43104958]\n", + " 4 [101:147] [43104121:43104259]\n", + " 5 [147:181] [43099778:43099880]\n", + " 6 [181:197] [43097245:43097293]\n", + " 7 [197:223] [43095846:43095924]\n", + " 8 [223:1365] [43091435:43094861]\n", + " 9 [1365:1395] [43090943:43091033]\n", + " 10 [1395:1451] [43082407:43082575]\n", + " 11 [1451:1494] [43076489:43076618]\n", + " 12 [1494:1558] [43074331:43074523]\n", + " 13 [1558:1662] [43070927:43071239]\n", + " 14 [1662:1691] [43067608:43067695]\n", + " 15 [1691:1717] [43063874:43063952]\n", + " 16 [1718:1731] [43063332:43063371]\n", + " 17 [1731:1759] [43057051:43057135]\n", + " 18 [1759:1777] [43051063:43051117]\n", + " 19 [1777:1802] [43049120:43049195]\n", + " 20 [1802:1822] [43047643:43047703]\n", + " 21 [1822:1863] [43045680:43045803]},\n", " 'urn:mavedb:00000053-a-2': {'chrom': '17',\n", " 'strand': 1,\n", " 'target': 'PSD95 PDZ3',\n", @@ -2739,19 +4282,6 @@ " 'hits': query_ranges hit_ranges\n", " 0 [0:156] [7196753:7196909]\n", " 1 [156:249] [7196479:7196572]},\n", - " 'urn:mavedb:00000045-a-1': {'chrom': '4',\n", - " 'strand': -1,\n", - " 'target': 'alpha-synuclein',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P37840',\n", - " 'coverage': '423 / 423, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [390:423] [89726627:89726660]\n", - " 1 [306:390] [89729193:89729277]\n", - " 2 [163:306] [89822245:89822388]\n", - " 3 [121:163] [89828142:89828184]\n", - " 4 [0:121] [89835546:89835667]},\n", " 'urn:mavedb:00000060-a-1': {'chrom': '1',\n", " 'strand': 1,\n", " 'target': 'TARDBP',\n", @@ -2765,16 +4295,6 @@ " 2 [402:543] [11018732:11018873]\n", " 3 [543:714] [11020428:11020599]\n", " 4 [714:1242] [11022123:11022651]},\n", - " 'urn:mavedb:00000061-h-1': {'chrom': '3',\n", - " 'strand': -1,\n", - " 'target': 'RAF',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P04049',\n", - " 'coverage': '117 / 117, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [54:117] [12611999:12612062]\n", - " 1 [0:54] [12618514:12618568]},\n", " 'urn:mavedb:00000013-a-1': {'chrom': '10',\n", " 'strand': 1,\n", " 'target': 'PTEN',\n", @@ -2801,34 +4321,15 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:601] [209815789:209816390]},\n", - " 'urn:mavedb:00000066-a-1': {'chrom': 'X',\n", - " 'strand': 1,\n", - " 'target': 'GDI1',\n", + " 'urn:mavedb:00000097-z-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 23',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P31150',\n", - " 'coverage': '1344 / 1344, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:45] [154437254:154437299]\n", - " 1 [45:153] [154438522:154438630]\n", - " 2 [153:253] [154438764:154438864]\n", - " 3 [253:388] [154439005:154439140]\n", - " 4 [388:587] [154439940:154440139]\n", - " 5 [587:719] [154440374:154440506]\n", - " 6 [719:819] [154441095:154441195]\n", - " 7 [819:991] [154441622:154441794]\n", - " 8 [991:1136] [154442110:154442255]\n", - " 9 [1136:1191] [154442373:154442428]\n", - " 10 [1191:1344] [154442519:154442672]},\n", - " 'urn:mavedb:00000021-a-1': {'chrom': '6',\n", - " 'strand': 1,\n", - " 'target': 'IRF4 enhancer',\n", - " 'target_type': 'Regulatory',\n", " 'uniprot': None,\n", - " 'coverage': '451 / 451, 100.0',\n", + " 'coverage': '108 / 108, 100.0',\n", " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:451] [396142:396593]},\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:108] [43045704:43045812]},\n", " 'urn:mavedb:00000094-a-9': {'chrom': '1',\n", " 'strand': 0,\n", " 'target': 'KCNQ4',\n", @@ -2864,61 +4365,15 @@ " 2 [163:306] [89822245:89822388]\n", " 3 [121:163] [89828142:89828184]\n", " 4 [0:121] [89835546:89835667]},\n", - " 'urn:mavedb:00000094-a-15': {'chrom': '11',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ1',\n", + " 'urn:mavedb:00000097-j-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 15',\n", " 'target_type': 'Protein coding',\n", " 'uniprot': None,\n", - " 'coverage': '676 / 676, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:129] [2445098:2445485]\n", - " 1 [129:159] [2527928:2528018]\n", - " 2 [159:201] [2570627:2570753]\n", - " 3 [201:227] [2571323:2571401]\n", - " 4 [227:260] [2572010:2572109]\n", - " 5 [260:307] [2572845:2572986]\n", - " 6 [307:344] [2583434:2583545]\n", - " 7 [344:375] [2585211:2585304]\n", - " 8 [375:417] [2587566:2587692]\n", - " 9 [417:462] [2588712:2588847]\n", - " 10 [462:505] [2661953:2662082]\n", - " 11 [505:529] [2768844:2768916]\n", - " 12 [529:561] [2775956:2776052]\n", - " 13 [561:577] [2776983:2777031]\n", - " 14 [577:598] [2777974:2778037]\n", - " 15 [598:676] [2847766:2848000]},\n", - " 'urn:mavedb:00000031-a-1': {'chrom': '5',\n", - " 'strand': 1,\n", - " 'target': 'TERT promoter',\n", - " 'target_type': 'Regulatory',\n", - " 'uniprot': None,\n", - " 'coverage': '259 / 259, 100.0',\n", + " 'coverage': '106 / 106, 100.0',\n", " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:259] [1294988:1295247]},\n", - " 'urn:mavedb:00000094-a-2': {'chrom': '1',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '695 / 695, 100.0',\n", - " 'identity': 99.9519692603266,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:104] [40784093:40784405]\n", - " 1 [105:135] [40817265:40817355]\n", - " 2 [135:177] [40818163:40818289]\n", - " 3 [177:236] [40818503:40818680]\n", - " 4 [236:278] [40819346:40819472]\n", - " 5 [278:315] [40819874:40819985]\n", - " 6 [315:346] [40820164:40820257]\n", - " 7 [346:376] [40822310:40822400]\n", - " 8 [376:430] [40824094:40824256]\n", - " 9 [430:504] [40831081:40831303]\n", - " 10 [504:537] [40833012:40833111]\n", - " 11 [537:581] [40834964:40835096]\n", - " 12 [581:624] [40837662:40837791]\n", - " 13 [624:695] [40838307:40838520]},\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:106] [43070917:43071023]},\n", " 'urn:mavedb:00000047-b-1': {'chrom': '3',\n", " 'strand': 1,\n", " 'target': 'CCR5',\n", @@ -2928,28 +4383,6 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:1053] [46372905:46373958]},\n", - " 'urn:mavedb:00000094-a-4': {'chrom': '1',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '695 / 695, 100.0',\n", - " 'identity': 99.9519692603266,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:104] [40784093:40784405]\n", - " 1 [105:135] [40817265:40817355]\n", - " 2 [135:177] [40818163:40818289]\n", - " 3 [177:236] [40818503:40818680]\n", - " 4 [236:278] [40819346:40819472]\n", - " 5 [278:315] [40819874:40819985]\n", - " 6 [315:346] [40820164:40820257]\n", - " 7 [346:376] [40822310:40822400]\n", - " 8 [376:430] [40824094:40824256]\n", - " 9 [430:504] [40831081:40831303]\n", - " 10 [504:537] [40833012:40833111]\n", - " 11 [537:581] [40834964:40835096]\n", - " 12 [581:624] [40837662:40837791]\n", - " 13 [624:695] [40838307:40838520]},\n", " 'urn:mavedb:00000003-b-1': {'chrom': '17',\n", " 'strand': -1,\n", " 'target': 'BRCA1 RING domain',\n", @@ -2972,72 +4405,28 @@ " 'target': 'PTEN',\n", " 'target_type': 'Protein coding',\n", " 'uniprot': 'P60484',\n", - " 'coverage': '1212 / 1212, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:79] [87864469:87864548]\n", - " 1 [79:164] [87894024:87894109]\n", - " 2 [164:209] [87925512:87925557]\n", - " 3 [209:253] [87931045:87931089]\n", - " 4 [253:492] [87933012:87933251]\n", - " 5 [492:634] [87952117:87952259]\n", - " 6 [634:801] [87957852:87958019]\n", - " 7 [801:1026] [87960893:87961118]\n", - " 8 [1026:1212] [87965286:87965472]},\n", - " 'urn:mavedb:00000059-a-1': {'chrom': '17',\n", - " 'strand': -1,\n", - " 'target': 'p53',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P04637',\n", - " 'coverage': '573 / 573, 100.0',\n", - " 'identity': 99.82547993019197,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [479:573] [7673743:7673837]\n", - " 1 [369:479] [7674180:7674290]\n", - " 2 [256:369] [7674858:7674971]\n", - " 3 [72:256] [7675052:7675236]\n", - " 4 [0:72] [7675993:7676065]},\n", - " 'urn:mavedb:00000061-a-1': {'chrom': '3',\n", - " 'strand': -1,\n", - " 'target': 'RAF',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P04049',\n", - " 'coverage': '117 / 117, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [54:117] [12611999:12612062]\n", - " 1 [0:54] [12618514:12618568]},\n", - " 'urn:mavedb:00000094-a-1': {'chrom': '1',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '695 / 695, 100.0',\n", - " 'identity': 99.9519692603266,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:104] [40784093:40784405]\n", - " 1 [105:135] [40817265:40817355]\n", - " 2 [135:177] [40818163:40818289]\n", - " 3 [177:236] [40818503:40818680]\n", - " 4 [236:278] [40819346:40819472]\n", - " 5 [278:315] [40819874:40819985]\n", - " 6 [315:346] [40820164:40820257]\n", - " 7 [346:376] [40822310:40822400]\n", - " 8 [376:430] [40824094:40824256]\n", - " 9 [430:504] [40831081:40831303]\n", - " 10 [504:537] [40833012:40833111]\n", - " 11 [537:581] [40834964:40835096]\n", - " 12 [581:624] [40837662:40837791]\n", - " 13 [624:695] [40838307:40838520]},\n", - " 'urn:mavedb:00000083-i-1': {'chrom': '11',\n", + " 'coverage': '1212 / 1212, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:79] [87864469:87864548]\n", + " 1 [79:164] [87894024:87894109]\n", + " 2 [164:209] [87925512:87925557]\n", + " 3 [209:253] [87931045:87931089]\n", + " 4 [253:492] [87933012:87933251]\n", + " 5 [492:634] [87952117:87952259]\n", + " 6 [634:801] [87957852:87958019]\n", + " 7 [801:1026] [87960893:87961118]\n", + " 8 [1026:1212] [87965286:87965472]},\n", + " 'urn:mavedb:00000061-a-1': {'chrom': '3',\n", " 'strand': -1,\n", - " 'target': 'Minigene exon - AC-rich enhancer',\n", - " 'target_type': 'Other noncoding',\n", - " 'uniprot': None,\n", - " 'coverage': '41 / 51, 80.3921568627451',\n", - " 'identity': 97.5609756097561,\n", + " 'target': 'RAF',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': 'P04049',\n", + " 'coverage': '117 / 117, 100.0',\n", + " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", - " 0 [10:51] [32416489:32416530]},\n", + " 0 [54:117] [12611999:12612062]\n", + " 1 [0:54] [12618514:12618568]},\n", " 'urn:mavedb:00000047-a-1': {'chrom': '3',\n", " 'strand': 1,\n", " 'target': 'CCR5',\n", @@ -3047,19 +4436,6 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:1053] [46372905:46373958]},\n", - " 'urn:mavedb:00000045-g-1': {'chrom': '4',\n", - " 'strand': -1,\n", - " 'target': 'alpha-synuclein',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P37840',\n", - " 'coverage': '423 / 423, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [390:423] [89726627:89726660]\n", - " 1 [306:390] [89729193:89729277]\n", - " 2 [163:306] [89822245:89822388]\n", - " 3 [121:163] [89828142:89828184]\n", - " 4 [0:121] [89835546:89835667]},\n", " 'urn:mavedb:00000035-a-1': {'chrom': '5',\n", " 'strand': 1,\n", " 'target': 'HMGCR',\n", @@ -3087,19 +4463,6 @@ " 16 [2298:2457] [75359397:75359556]\n", " 17 [2457:2612] [75359984:75360139]\n", " 18 [2612:2667] [75360287:75360342]},\n", - " 'urn:mavedb:00000045-j-1': {'chrom': '4',\n", - " 'strand': -1,\n", - " 'target': 'alpha-synuclein',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P37840',\n", - " 'coverage': '423 / 423, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [390:423] [89726627:89726660]\n", - " 1 [306:390] [89729193:89729277]\n", - " 2 [163:306] [89822245:89822388]\n", - " 3 [121:163] [89828142:89828184]\n", - " 4 [0:121] [89835546:89835667]},\n", " 'urn:mavedb:00000015-a-1': {'chrom': 'X',\n", " 'strand': 1,\n", " 'target': 'F9 promoter',\n", @@ -3157,15 +4520,6 @@ " 4 [307:396] [130222649:130222738]\n", " 5 [396:474] [130223081:130223159]\n", " 6 [474:573] [130226388:130226487]},\n", - " 'urn:mavedb:00000026-a-1': {'chrom': '8',\n", - " 'strand': 1,\n", - " 'target': 'MYC enhancer (rs11986220)',\n", - " 'target_type': 'Regulatory',\n", - " 'uniprot': None,\n", - " 'coverage': '463 / 463, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:463] [127519269:127519732]},\n", " 'urn:mavedb:00000046-a-3': {'chrom': '3',\n", " 'strand': 1,\n", " 'target': 'CD86',\n", @@ -3175,34 +4529,6 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:81] [122109290:122109371]},\n", - " 'urn:mavedb:00000083-j-1': {'chrom': '11',\n", - " 'strand': -1,\n", - " 'target': 'Minigene exon - pyrimidine sequence',\n", - " 'target_type': 'Other noncoding',\n", - " 'uniprot': None,\n", - " 'coverage': '42 / 51, 82.3529411764706',\n", - " 'identity': 97.61904761904762,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [9:51] [32416489:32416531]},\n", - " 'urn:mavedb:00000049-a-4': {'chrom': '1',\n", - " 'strand': -1,\n", - " 'target': 'MTHFR',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P42898',\n", - " 'coverage': '1971 / 1971, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [1752:1971] [11790679:11790898]\n", - " 1 [1632:1752] [11791206:11791326]\n", - " 2 [1530:1632] [11792277:11792379]\n", - " 3 [1347:1530] [11793906:11794089]\n", - " 4 [1166:1347] [11794357:11794538]\n", - " 5 [1031:1166] [11794728:11794863]\n", - " 6 [780:1031] [11795097:11795348]\n", - " 7 [586:780] [11796205:11796399]\n", - " 8 [475:586] [11800211:11800322]\n", - " 9 [236:475] [11801160:11801399]\n", - " 10 [0:236] [11802880:11803116]},\n", " 'urn:mavedb:00000068-c-1': {'chrom': '17',\n", " 'strand': -1,\n", " 'target': 'TP53 (P72R)',\n", @@ -3254,15 +4580,6 @@ " 'hits': query_ranges hit_ranges\n", " 0 [54:117] [12611999:12612062]\n", " 1 [0:54] [12618514:12618568]},\n", - " 'urn:mavedb:00000083-e-1': {'chrom': '11',\n", - " 'strand': -1,\n", - " 'target': 'Minigene exon - hnRNP D binding site',\n", - " 'target_type': 'Other noncoding',\n", - " 'uniprot': None,\n", - " 'coverage': '42 / 51, 82.3529411764706',\n", - " 'identity': 97.61904761904762,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [9:51] [32416489:32416531]},\n", " 'urn:mavedb:00000019-a-1': {'chrom': '11',\n", " 'strand': 1,\n", " 'target': 'HBG1 promoter',\n", @@ -3272,15 +4589,6 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:274] [5249804:5250078]},\n", - " 'urn:mavedb:00000014-a-1': {'chrom': '2',\n", - " 'strand': 1,\n", - " 'target': 'BCL11A enhancer',\n", - " 'target_type': 'Regulatory',\n", - " 'uniprot': None,\n", - " 'coverage': '600 / 600, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:600] [60494939:60495539]},\n", " 'urn:mavedb:00000055-b-1': {'chrom': '13',\n", " 'strand': 1,\n", " 'target': 'NUDT15',\n", @@ -3292,65 +4600,6 @@ " 0 [0:158] [48037746:48037904]\n", " 1 [158:355] [48040919:48041116]\n", " 2 [355:495] [48045659:48045799]},\n", - " 'urn:mavedb:00000001-b-2': {'chrom': '2',\n", - " 'strand': -1,\n", - " 'target': 'SUMO1',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P63165',\n", - " 'coverage': '297 / 306, 97.05882352941177',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [237:306] [202207252:202207321]\n", - " 1 [165:237] [202210734:202210806]\n", - " 2 [87:165] [202214356:202214434]\n", - " 3 [9:87] [202220031:202220109]},\n", - " 'urn:mavedb:00000094-a-3': {'chrom': '1',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '695 / 695, 100.0',\n", - " 'identity': 99.9519692603266,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:104] [40784093:40784405]\n", - " 1 [105:135] [40817265:40817355]\n", - " 2 [135:177] [40818163:40818289]\n", - " 3 [177:236] [40818503:40818680]\n", - " 4 [236:278] [40819346:40819472]\n", - " 5 [278:315] [40819874:40819985]\n", - " 6 [315:346] [40820164:40820257]\n", - " 7 [346:376] [40822310:40822400]\n", - " 8 [376:430] [40824094:40824256]\n", - " 9 [430:504] [40831081:40831303]\n", - " 10 [504:537] [40833012:40833111]\n", - " 11 [537:581] [40834964:40835096]\n", - " 12 [581:624] [40837662:40837791]\n", - " 13 [624:695] [40838307:40838520]},\n", - " 'urn:mavedb:00000061-g-1': {'chrom': '3',\n", - " 'strand': -1,\n", - " 'target': 'RAF',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P04049',\n", - " 'coverage': '117 / 117, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [54:117] [12611999:12612062]\n", - " 1 [0:54] [12618514:12618568]},\n", - " 'urn:mavedb:00000001-d-1': {'chrom': '7',\n", - " 'strand': -1,\n", - " 'target': 'TPK1',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'Q9H3S4',\n", - " 'coverage': '585 / 585, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [466:585] [144453544:144453663]\n", - " 1 [354:466] [144548490:144548602]\n", - " 2 [258:354] [144623165:144623261]\n", - " 3 [185:258] [144648806:144648879]\n", - " 4 [115:185] [144682908:144682978]\n", - " 5 [43:115] [144765879:144765951]\n", - " 6 [0:43] [144835559:144835602]},\n", " 'urn:mavedb:00000057-a-1': {'chrom': '11',\n", " 'strand': -1,\n", " 'target': 'Ras',\n", @@ -3363,17 +4612,15 @@ " 1 [287:447] [533452:533612]\n", " 2 [108:287] [533765:533944]\n", " 3 [0:108] [534211:534319]},\n", - " 'urn:mavedb:00000055-a-1': {'chrom': '13',\n", - " 'strand': 1,\n", - " 'target': 'NUDT15',\n", + " 'urn:mavedb:00000097-n-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 17',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'Q9NV35',\n", - " 'coverage': '495 / 495, 100.0',\n", + " 'uniprot': None,\n", + " 'coverage': '98 / 98, 100.0',\n", " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", - " 0 [0:158] [48037746:48037904]\n", - " 1 [158:355] [48040919:48041116]\n", - " 2 [355:495] [48045659:48045799]},\n", + " 0 [0:98] [43063863:43063961]},\n", " 'urn:mavedb:00000001-d-2': {'chrom': '7',\n", " 'strand': -1,\n", " 'target': 'TPK1',\n", @@ -3389,28 +4636,6 @@ " 4 [115:185] [144682908:144682978]\n", " 5 [43:115] [144765879:144765951]\n", " 6 [0:43] [144835559:144835602]},\n", - " 'urn:mavedb:00000094-a-10': {'chrom': '1',\n", - " 'strand': 0,\n", - " 'target': 'KCNQ4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': None,\n", - " 'coverage': '695 / 695, 100.0',\n", - " 'identity': 99.9519692603266,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:104] [40784093:40784405]\n", - " 1 [105:135] [40817265:40817355]\n", - " 2 [135:177] [40818163:40818289]\n", - " 3 [177:236] [40818503:40818680]\n", - " 4 [236:278] [40819346:40819472]\n", - " 5 [278:315] [40819874:40819985]\n", - " 6 [315:346] [40820164:40820257]\n", - " 7 [346:376] [40822310:40822400]\n", - " 8 [376:430] [40824094:40824256]\n", - " 9 [430:504] [40831081:40831303]\n", - " 10 [504:537] [40833012:40833111]\n", - " 11 [537:581] [40834964:40835096]\n", - " 12 [581:624] [40837662:40837791]\n", - " 13 [624:695] [40838307:40838520]},\n", " 'urn:mavedb:00000017-a-1': {'chrom': '22',\n", " 'strand': 1,\n", " 'target': 'GP1BB promoter',\n", @@ -3452,28 +4677,6 @@ " 'identity': 97.5609756097561,\n", " 'hits': query_ranges hit_ranges\n", " 0 [10:51] [32416489:32416530]},\n", - " 'urn:mavedb:00000045-i-1': {'chrom': '4',\n", - " 'strand': -1,\n", - " 'target': 'alpha-synuclein',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P37840',\n", - " 'coverage': '423 / 423, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [390:423] [89726627:89726660]\n", - " 1 [306:390] [89729193:89729277]\n", - " 2 [163:306] [89822245:89822388]\n", - " 3 [121:163] [89828142:89828184]\n", - " 4 [0:121] [89835546:89835667]},\n", - " 'urn:mavedb:00000032-a-1': {'chrom': '2',\n", - " 'strand': 1,\n", - " 'target': 'UC88 enhancer',\n", - " 'target_type': 'Regulatory',\n", - " 'uniprot': None,\n", - " 'coverage': '590 / 591, 99.83079526226734',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:590] [161238407:161238997]},\n", " 'urn:mavedb:00000031-d-1': {'chrom': '5',\n", " 'strand': 1,\n", " 'target': 'TERT promoter',\n", @@ -3483,6 +4686,18 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:259] [1294988:1295247]},\n", + " 'urn:mavedb:00000106-c-1': {'chrom': '12',\n", + " 'strand': 0,\n", + " 'target': 'AID',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '196 / 198, 98.98989898989899',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [2:52] [8606864:8607014]\n", + " 1 [52:142] [8605215:8605485]\n", + " 2 [142:181] [8604806:8604923]\n", + " 3 [181:198] [8604286:8604337]},\n", " 'urn:mavedb:00000020-a-1': {'chrom': '20',\n", " 'strand': 1,\n", " 'target': 'HNF4A promoter',\n", @@ -3500,38 +4715,7 @@ " 'coverage': '620 / 620, 100.0',\n", " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", - " 0 [0:620] [169082571:169083191]},\n", - " 'urn:mavedb:00000053-a-1': {'chrom': '17',\n", - " 'strand': 1,\n", - " 'target': 'PSD95 PDZ3',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P78352',\n", - " 'coverage': '249 / 249, 100.0',\n", - " 'identity': 74.6987951807229,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:156] [7196753:7196909]\n", - " 1 [156:249] [7196479:7196572]},\n", - " 'urn:mavedb:00000091-a-1': {'chrom': '7',\n", - " 'strand': 0,\n", - " 'target': 'BRAF',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P15056',\n", - " 'coverage': '118 / 119, 99.15966386554622',\n", - " 'identity': 98.86039886039886,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [1:29] [140777992:140778076]\n", - " 1 [29:88] [140776913:140777090]\n", - " 2 [89:105] [140754184:140754232]\n", - " 3 [105:119] [140753349:140753391]},\n", - " 'urn:mavedb:00000048-c-1': {'chrom': '2',\n", - " 'strand': -1,\n", - " 'target': 'CXCR4',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P61073',\n", - " 'coverage': '1041 / 1053, 98.86039886039886',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [12:1053] [136114871:136115912]},\n", + " 0 [0:620] [169082571:169083191]},\n", " 'urn:mavedb:00000045-b-1': {'chrom': '4',\n", " 'strand': -1,\n", " 'target': 'alpha-synuclein',\n", @@ -3571,15 +4755,6 @@ " 6 [961:1149] [94981182:94981370]\n", " 7 [1149:1291] [94986032:94986174]\n", " 8 [1291:1470] [94988846:94989025]},\n", - " 'urn:mavedb:00000031-c-1': {'chrom': '5',\n", - " 'strand': 1,\n", - " 'target': 'TERT promoter',\n", - " 'target_type': 'Regulatory',\n", - " 'uniprot': None,\n", - " 'coverage': '259 / 259, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:259] [1294988:1295247]},\n", " 'urn:mavedb:00000016-a-1': {'chrom': '9',\n", " 'strand': 1,\n", " 'target': 'FOXE1 promoter',\n", @@ -3589,15 +4764,6 @@ " 'identity': 100.0,\n", " 'hits': query_ranges hit_ranges\n", " 0 [0:600] [97853254:97853854]},\n", - " 'urn:mavedb:00000051-b-1': {'chrom': '17',\n", - " 'strand': 1,\n", - " 'target': 'ErbB2',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P04626',\n", - " 'coverage': '71 / 72, 98.61111111111111',\n", - " 'identity': 95.77464788732394,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:71] [39723322:39723393]},\n", " 'urn:mavedb:00000029-b-1': {'chrom': '1',\n", " 'strand': 1,\n", " 'target': 'SORT1 enhancer (flipped)',\n", @@ -3626,6 +4792,15 @@ " 8 [475:586] [11800211:11800322]\n", " 9 [236:475] [11801160:11801399]\n", " 10 [0:236] [11802880:11803116]},\n", + " 'urn:mavedb:00000097-y-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 23',\n", + " 'target_type': 'Protein coding',\n", + " 'uniprot': None,\n", + " 'coverage': '108 / 108, 100.0',\n", + " 'identity': 100.0,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:108] [43045704:43045812]},\n", " 'urn:mavedb:00000005-a-1': {'chrom': '21',\n", " 'strand': -1,\n", " 'target': 'CBS',\n", @@ -3649,18 +4824,15 @@ " 12 [316:451] [43066242:43066377]\n", " 13 [209:316] [43068508:43068615]\n", " 14 [0:209] [43071984:43072193]},\n", - " 'urn:mavedb:00000001-b-1': {'chrom': '2',\n", + " 'urn:mavedb:00000097-a-1': {'chrom': '17',\n", " 'strand': -1,\n", - " 'target': 'SUMO1',\n", + " 'target': 'BRCA1 Exon 2',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P63165',\n", - " 'coverage': '297 / 306, 97.05882352941177',\n", + " 'uniprot': None,\n", + " 'coverage': '106 / 106, 100.0',\n", " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [237:306] [202207252:202207321]\n", - " 1 [165:237] [202210734:202210806]\n", - " 2 [87:165] [202214356:202214434]\n", - " 3 [9:87] [202220031:202220109]},\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:106] [43124012:43124118]},\n", " 'urn:mavedb:00000003-a-1': {'chrom': '17',\n", " 'strand': -1,\n", " 'target': 'BRCA1 RING domain',\n", @@ -3738,58 +4910,39 @@ " 'hits': query_ranges hit_ranges\n", " 0 [0:60] [102114329:102114389]\n", " 1 [60:102] [102162450:102162492]},\n", - " 'urn:mavedb:00000057-b-1': {'chrom': '11',\n", - " 'strand': -1,\n", - " 'target': 'Ras',\n", + " 'urn:mavedb:00000107-a-1': {'chrom': '9',\n", + " 'strand': 0,\n", + " 'target': 'PSAT1',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P01112',\n", - " 'coverage': '495 / 495, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [447:495] [532707:532755]\n", - " 1 [287:447] [533452:533612]\n", - " 2 [108:287] [533765:533944]\n", - " 3 [0:108] [534211:534319]},\n", - " 'urn:mavedb:00000083-a-1': {'chrom': '11',\n", - " 'strand': -1,\n", - " 'target': 'Minigene exon - Wilms’ tumor gene',\n", - " 'target_type': 'Other noncoding',\n", - " 'uniprot': None,\n", - " 'coverage': '51 / 51, 100.0',\n", - " 'identity': 98.0392156862745,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:51] [32416489:32416540]},\n", - " 'urn:mavedb:00000024-a-1': {'chrom': '10',\n", - " 'strand': 1,\n", - " 'target': 'MSMB promoter',\n", - " 'target_type': 'Regulatory',\n", " 'uniprot': None,\n", - " 'coverage': '591 / 591, 100.0',\n", - " 'identity': 100.0,\n", + " 'coverage': '370 / 370, 100.0',\n", + " 'identity': 99.9096657633243,\n", " 'hits': query_ranges hit_ranges\n", - " 0 [0:591] [46046243:46046834]},\n", - " 'urn:mavedb:00000045-f-1': {'chrom': '4',\n", - " 'strand': -1,\n", - " 'target': 'alpha-synuclein',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P37840',\n", - " 'coverage': '423 / 423, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [390:423] [89726627:89726660]\n", - " 1 [306:390] [89729193:89729277]\n", - " 2 [163:306] [89822245:89822388]\n", - " 3 [121:163] [89828142:89828184]\n", - " 4 [0:121] [89835546:89835667]},\n", - " 'urn:mavedb:00000072-a-1': {'chrom': '14',\n", + " 0 [0:20] [78297210:78297270]\n", + " 1 [20:40] [78300601:78300661]\n", + " 2 [40:64] [78301952:78302024]\n", + " 3 [64:132] [78304735:78304939]\n", + " 4 [133:189] [78306315:78306483]\n", + " 5 [189:245] [78308410:78308578]\n", + " 6 [245:290] [78317670:78317805]\n", + " 7 [290:335] [78328051:78328186]\n", + " 8 [335:370] [78328978:78329083]},\n", + " 'urn:mavedb:00000103-d-1': {'chrom': '22',\n", " 'strand': 0,\n", - " 'target': 'IGHG1',\n", + " 'target': 'MAPK1',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P01857',\n", - " 'coverage': '106 / 106, 100.0',\n", - " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:106] [105741478:105741796]},\n", + " 'uniprot': None,\n", + " 'coverage': '360 / 360, 100.0',\n", + " 'identity': 99.9071494893222,\n", + " 'hits': query_ranges hit_ranges\n", + " 0 [0:39] [21867323:21867440]\n", + " 1 [40:101] [21807662:21807845]\n", + " 2 [101:164] [21805849:21806038]\n", + " 3 [164:203] [21799011:21799128]\n", + " 4 [203:241] [21788694:21788808]\n", + " 5 [241:285] [21788257:21788389]\n", + " 6 [285:322] [21772872:21772983]\n", + " 7 [322:360] [21769206:21769320]},\n", " 'urn:mavedb:00000029-a-2': {'chrom': '1',\n", " 'strand': 1,\n", " 'target': 'SORT1 enhancer',\n", @@ -3809,187 +4962,1165 @@ " 'hits': query_ranges hit_ranges\n", " 0 [54:117] [12611999:12612062]\n", " 1 [0:54] [12618514:12618568]},\n", - " 'urn:mavedb:00000095-b-1': {'chrom': '10',\n", - " 'strand': 1,\n", - " 'target': 'CYP2C9',\n", - " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P11712',\n", - " 'coverage': '1470 / 1470, 100.0',\n", - " 'identity': 99.1991991991992,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:168] [94938682:94938850]\n", - " 1 [168:331] [94941857:94942020]\n", - " 2 [331:481] [94942191:94942341]\n", - " 3 [481:536] [94947778:94947833]\n", - " 4 [937:959] [94972221:94972243]\n", - " 5 [1029:1149] [94981250:94981370]\n", - " 6 [1149:1291] [94986032:94986174]\n", - " 7 [1291:1470] [94988846:94989025]},\n", - " 'urn:mavedb:00000001-a-1': {'chrom': '16',\n", - " 'strand': 1,\n", - " 'target': 'UBE2I',\n", + " 'urn:mavedb:00000097-q-1': {'chrom': '17',\n", + " 'strand': -1,\n", + " 'target': 'BRCA1 Exon 19',\n", " 'target_type': 'Protein coding',\n", - " 'uniprot': 'P63279',\n", - " 'coverage': '477 / 477, 100.0',\n", + " 'uniprot': None,\n", + " 'coverage': '104 / 104, 100.0',\n", " 'identity': 100.0,\n", - " 'hits': query_ranges hit_ranges\n", - " 0 [0:66] [1314030:1314096]\n", - " 1 [66:150] [1314292:1314376]\n", - " 2 [150:223] [1315653:1315726]\n", - " 3 [223:333] [1320173:1320283]\n", - " 4 [333:413] [1320437:1320517]\n", - " 5 [413:477] [1324729:1324793]}}" + " 'hits': query_ranges hit_ranges\n", + " 0 [0:104] [43057041:43057145]}}" + ] + }, + "execution_count": 12, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "mave_blat_dict" + ] + }, + { + "cell_type": "code", + "execution_count": 13, + "id": "d66f6830", + "metadata": {}, + "outputs": [], + "source": [ + "with open('results/mave_blat.pickle', 'wb') as fn:\n", + " pickle.dump(mave_blat_dict, fn, protocol=pickle.HIGHEST_PROTOCOL)" + ] + }, + { + "cell_type": "markdown", + "id": "8ad39211", + "metadata": {}, + "source": [ + "## Part 2: BLAT Output to Transcript Selection" + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "id": "1059d30e", + "metadata": {}, + "outputs": [], + "source": [ + "## Helper functions\n", + "\n", + "def get_start(string):\n", + " return int(string.split(':')[0].strip('['))\n", + "\n", + "def get_end(string):\n", + " return int(string.split(':')[1].strip(']'))\n", + "\n", + "def get_locs_list(hitsdat):\n", + " locs_list = []\n", + " for i in range(len(hitsdat.index)):\n", + " start = get_start(hitsdat.at[i, 'hit_ranges'])\n", + " end = get_end(hitsdat.at[i, 'hit_ranges'])\n", + " locs_list.append([start,end])\n", + " return locs_list\n", + "\n", + "def get_hits_list(hitsdat):\n", + " hits_list = []\n", + " for i in range(len(hitsdat.index)):\n", + " start = get_start(hitsdat.at[i, 'query_ranges'])\n", + " end = get_end(hitsdat.at[i, 'query_ranges'])\n", + " hits_list.append([start,end])\n", + " return hits_list\n", + "\n", + "def get_query_hits(dat):\n", + " query_list = []\n", + " hits_list = []\n", + " for i in range(len(dat.index)):\n", + " query_start = get_start(dat.at[i, 'query_ranges'])\n", + " query_end = get_end(dat.at[i, 'query_ranges'])\n", + " query_list.append([query_start, query_end])\n", + " hit_start = get_start(dat.at[i, 'hit_ranges'])\n", + " hit_end = get_end(dat.at[i, 'hit_ranges'])\n", + " hits_list.append([hit_start, hit_end])\n", + " return query_list, hits_list\n", + "\n", + "def get_ga4gh(dp, ref):\n", + " aliases = dp.get_metadata(ref)['aliases']\n", + " f = filter(lambda x: 'ga4gh' in x, aliases)\n", + " return 'ga4gh:' + list(f)[0].split(':')[1]\n", + "\n", + "def get_chr(dp, chrom):\n", + " aliases = dp.get_metadata('GRCh38:' + chrom)['aliases']\n", + " f = filter(lambda x: 'refseq' in x, aliases)\n", + " return list(f)[0].split(':')[1]\n", + "\n", + "def modify_hgvs(var, ref, off, hp):\n", + " if len(var) == 3 or var == '_wt' or var == '_sy' or '[' in var:\n", + " return var\n", + " var = ref + ':' + var\n", + " var = hp.parse_hgvs_variant(var)\n", + " var.posedit.pos.start.base = var.posedit.pos.start.base + off\n", + " var.posedit.pos.end.base = var.posedit.pos.end.base + off\n", + " return(str(var))\n", + "\n", + "def blat_check(i):\n", + " item = mave_blat_dict[dat.at[i, 'urn']]\n", + " if item['uniprot'] == None:\n", + " test = dat.at[i, 'target'].split(' ')\n", + " for j in range(len(test)):\n", + " try:\n", + " out = qh.normalize(test[j]).gene_descriptor\n", + " gene_dat = [out.label, out.extensions[2].value['chr']]\n", + " if item['chrom'] != gene_dat[1]:\n", + " return False\n", + " else:\n", + " return True\n", + " except:\n", + " continue\n", + "\n", + "def get_haplotype_allele(var, ref, offset, l, tr, dp, ts, mapped, ranges, hits, strand):\n", + " var = var.lstrip(f'{l}.')\n", + "\n", + " if '[' in var:\n", + " var = var[1:][:-1]\n", + " varlist = var.split(';')\n", + " varlist = list(set(varlist))\n", + " else:\n", + " varlist = list()\n", + " varlist.append(var)\n", + "\n", + " locs = {}\n", + " alleles = []\n", + "\n", + " for i in range(len(varlist)):\n", + " try:\n", + " hgvs_string = ref + ':'+ l +'.' + varlist[i]\n", + " allele = tr.translate_from(hgvs_string, 'hgvs')\n", + " \n", + " if mapped == 'pre':\n", + " allele.location.sequence_id = 'ga4gh:SQ.' + sha512t24u(ts.encode('ascii'))\n", + " if 'dup' in hgvs_string:\n", + " allele.state.sequence = 2*str(sr[str(allele.location.sequence_id)][allele.location.start.value:allele.location.end.value])\n", + " \n", + " else:\n", + " if l != 'g':\n", + " allele.location.start.value = allele.location.start.value + offset\n", + " allele.location.end.value = allele.location.end.value + offset\n", + " if 'dup' in hgvs_string:\n", + " allele.state.sequence = 2*str(sr[str(allele.location.sequence_id)][allele.location.start.value:allele.location.end.value])\n", + " \n", + " else:\n", + " start = allele.location.start.value\n", + " if len(hits) == 1 and strand == 1:\n", + " i = 0\n", + " diff = start - hits[i][0]\n", + " diff2 = allele.location.end.value - start\n", + " allele.location.start.value = ranges[i][0] + diff\n", + " allele.location.end.value = allele.location.start.value + diff2\n", + " else:\n", + " for i in range(len(hits)):\n", + " if start >= hits[i][0] and start < hits[i][1]:\n", + " break\n", + " diff = start - hits[i][0]\n", + " diff2 = allele.location.end.value - start\n", + " if strand == 1: # positive orientation\n", + " allele.location.start.value = ranges[i][0] + diff\n", + " allele.location.end.value = allele.location.start.value + diff2\n", + " if 'dup' in hgvs_string:\n", + " allele.state.sequence = 2*str(sr[str(allele.location.sequence_id)][allele.location.start.value:allele.location.end.value])\n", + " else: \n", + " allele.location.start.value = ranges[i][1] - diff - diff2\n", + " allele.location.end.value = allele.location.start.value + diff2\n", + " if 'dup' in hgvs_string:\n", + " allele.state.sequence = 2*str(sr[str(allele.location.sequence_id)][allele.location.start.value:allele.location.end.value])\n", + " allele.state.sequence = str(Seq(str(allele.state.sequence)).reverse_complement())\n", + " \n", + " allele = normalize(allele, data_proxy = dp) \n", + " allele.id = ga4gh_identify(allele)\n", + " alleles.append(allele)\n", + " except:\n", + " vrstext = {'definition':ref + ':'+ l +'.' + varlist[i], 'type': 'Text'}\n", + " return vrstext\n", + " \n", + " if len(alleles) == 1: # Not haplotype\n", + " return alleles[0]\n", + " else:\n", + " return models.Haplotype(members = alleles)\n", + " \n", + "def get_clingen_id(hgvs):\n", + " url = 'https://reg.genome.network/allele?hgvs=' + hgvs\n", + " page = requests.get(url).json()\n", + " page = page['@id']\n", + " try:\n", + " return page.split('/')[4]\n", + " except:\n", + " return 'NA'" + ] + }, + { + "cell_type": "code", + "execution_count": 15, + "id": "24d27355", + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "***Using Gene Database Endpoint: http://localhost:8000***\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/bs4/__init__.py:435: MarkupResemblesLocatorWarning: The input looks more like a filename than markup. You may want to open this file and pass the filehandle into Beautiful Soup.\n", + " warnings.warn(\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "['urn:mavedb:00000097-r-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-o-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-h-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-w-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-g-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-b-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-k-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-p-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-x-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-v-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-m-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-f-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-s-1', 'no transcripts found']\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/bs4/builder/__init__.py:545: XMLParsedAsHTMLWarning: It looks like you're parsing an XML document using an HTML parser. If this really is an HTML document (maybe it's XHTML?), you can ignore or filter this warning. If it's XML, you should know that using an XML parser will be more reliable. To parse this document as XML, make sure you have the lxml package installed, and pass the keyword argument `features=\"xml\"` into the BeautifulSoup constructor.\n", + " warnings.warn(\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "['urn:mavedb:00000097-e-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-c-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-t-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-l-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-u-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-d-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-n-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-a-1', 'no transcripts found']\n", + "['urn:mavedb:00000097-q-1', 'no transcripts found']\n" + ] + }, + { + "data": { + "text/plain": [ + "{'urn:mavedb:00000041-a-1': ['NP_938033.1',\n", + " 269,\n", + " 'urn:mavedb:00000041-a-1',\n", + " True],\n", + " 'urn:mavedb:00000048-a-1': ['NP_003458.1',\n", + 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'urn:mavedb:00000061-b-1': ['NP_002871.1',\n", + " 51,\n", + " 'urn:mavedb:00000061-b-1',\n", + " True],\n", + " 'urn:mavedb:00000097-q-1': []}" ] }, - "execution_count": 12, + "execution_count": 15, "metadata": {}, "output_type": "execute_result" } ], "source": [ - "mave_blat_dict" - ] - }, - { - "cell_type": "markdown", - "id": "8ad39211", - "metadata": {}, - "source": [ - "## Part 2: BLAT Output to Transcript Selection" - ] - }, - { - "cell_type": "code", - "execution_count": 13, - "id": "1059d30e", - "metadata": {}, - "outputs": [], - "source": [ - "## Helper functions\n", - "\n", - "def get_start(string):\n", - " return int(string.split(':')[0].strip('['))\n", - "\n", - "def get_end(string):\n", - " return int(string.split(':')[1].strip(']'))\n", + "## UTA Transcript Selection\n", + "nest_asyncio.apply()\n", + "mane = MANETranscriptMappings()\n", + "utadb = UTADatabase(db_pwd = 'uta')\n", + "qh = QueryHandler()\n", + "dp = SeqRepoDataProxy(sr = sr)\n", "\n", - "def get_locs_list(hitsdat):\n", - " locs_list = []\n", - " for i in range(len(hitsdat.index)):\n", - " start = get_start(hitsdat.at[i, 'hit_ranges'])\n", - " end = get_end(hitsdat.at[i, 'hit_ranges'])\n", - " locs_list.append([start,end])\n", - " return locs_list\n", + "mappings_dict = {}\n", + "mave_dat = pd.read_csv('results/mave_dat.csv')\n", + "dat = mave_dat\n", + "with open('results/mave_blat.pickle', 'rb') as fn:\n", + " mave_blat_dict = pickle.load(fn)\n", "\n", - "def get_query_hits(dat):\n", - " query_list = []\n", - " hits_list = []\n", - " for i in range(len(dat.index)):\n", - " query_start = get_start(dat.at[i, 'query_ranges'])\n", - " query_end = get_end(dat.at[i, 'query_ranges'])\n", - " query_list.append([query_start, query_end])\n", - " hit_start = get_start(dat.at[i, 'hit_ranges'])\n", - " hit_end = get_end(dat.at[i, 'hit_ranges'])\n", - " hits_list.append([hit_start, hit_end])\n", - " return query_list, hits_list\n", + "for j in range(len(dat.index)):\n", + " if dat.at[j, 'target_type'] == 'Protein coding':\n", + " item = mave_blat_dict[dat.at[j,'urn']]\n", + " #if blat_check(j) == False:\n", + " # mappings_dict[dat.at[j, 'urn']] = 'BLAT hit not found on correct chromosome'\n", + " # continue\n", + " if item['chrom'] == 'NA':\n", + " continue\n", + " locs = get_locs_list(item['hits'])\n", + " chrom = get_chr(dp, item['chrom'])\n", "\n", - "def get_ga4gh(dp, ref):\n", - " aliases = dp.get_metadata(ref)['aliases']\n", - " f = filter(lambda x: 'ga4gh' in x, aliases)\n", - " return 'ga4gh:' + list(f)[0].split(':')[1]\n", + " try:\n", + " uniprot = dat.at[j, 'uniprot_id']\n", + " gsymb = qh.normalize(str(f'uniprot:{uniprot}')).gene_descriptor.label\n", + " except: \n", + " temp = dat.at[j, 'target'].split(' ')\n", + " gsymb = qh.normalize(temp[0]).gene_descriptor.label\n", "\n", - "def get_chr(dp, chrom):\n", - " aliases = dp.get_metadata('GRCh38:' + chrom)['aliases']\n", - " f = filter(lambda x: 'refseq' in x, aliases)\n", - " return list(f)[0].split(':')[1]\n", + " async def mapq():\n", + " transcript_lists = []\n", + " for i in range(len(locs)):\n", + " testquery = (f\"\"\"select *\n", + " from uta_20210129.tx_exon_aln_v\n", + " where hgnc = '{gsymb}'\n", + " and {locs[i][0]} between alt_start_i and alt_end_i\n", + " or {locs[i][1]} between alt_start_i and alt_end_i\n", + " and alt_ac = '{chrom}'\"\"\") \n", + " \n", + " out = await utadb.execute_query(testquery)\n", + " tl = []\n", + " for j in range(len(out)):\n", + " if out[j]['tx_ac'].startswith('NR_') == False:\n", + " tl.append(out[j]['tx_ac'])\n", + " if tl != []:\n", + " transcript_lists.append(tl)\n", + " return(transcript_lists)\n", "\n", - "def modify_hgvs(var, ref, off, hp):\n", - " if len(var) == 3 or var == '_wt' or var == '_sy' or '[' in var:\n", - " return var\n", - " var = ref + ':' + var\n", - " var = hp.parse_hgvs_variant(var)\n", - " var.posedit.pos.start.base = var.posedit.pos.start.base + off\n", - " var.posedit.pos.end.base = var.posedit.pos.end.base + off\n", - " return(str(var))\n", + " ts = asyncio.run(mapq())\n", + " try:\n", + " isect = list(set.intersection(*map(set,ts)))\n", + " except:\n", + " try: # Look for transcripts using uniprot id\n", + " url = 'https://www.uniprot.org/uniprot/' + str(dat.at[j, 'uniprot_id']) + '.xml'\n", + " page = requests.get(url)\n", + " page = BeautifulSoup(page.text)\n", + " page = page.find_all('sequence')\n", + " up = page[1].get_text()\n", "\n", - "def blat_check(i):\n", - " item = mave_blat_dict[dat.at[i, 'urn']]\n", - " if item['uniprot'] == None:\n", - " test = dat.at[i, 'target'].split(' ')\n", - " for j in range(len(test)):\n", - " try:\n", - " out = qh.normalize(test[j]).gene_descriptor\n", - " gene_dat = [out.label, out.extensions[2].value['chr']]\n", - " if item['chrom'] != gene_dat[1]:\n", - " return False\n", + " stri = str(dat.at[j,'target_sequence'])\n", + " if up.find(stri) != -1:\n", + " full_match = True\n", " else:\n", - " return True\n", + " full_match = False\n", + " start = up.find(stri[:10])\n", + " mappings_dict[dat.at[j,'urn']] = [dat.at[j, 'uniprot_id'], start, dat.at[j, 'urn'], full_match]\n", + " continue\n", " except:\n", + " print([dat.at[j, 'urn'], 'no transcripts found'])\n", + " mappings_dict[dat.at[j,'urn']] = []\n", " continue\n", "\n", - "def get_haplotype_allele(var, ref, offset, l, tr, dp, ts, mapped):\n", - " var = var.lstrip(f'{l}.')\n", - " \n", - " if '[' in var:\n", - " var = var[1:][:-1]\n", - " varlist = var.split(';')\n", - " varlist = list(set(varlist))\n", - " else:\n", - " varlist = list()\n", - " varlist.append(var)\n", - "\n", - " locs = {}\n", - " alleles = []\n", - "\n", - " for i in range(len(varlist)):\n", - " try:\n", - " allele = tr.translate_from(ref + ':'+ l +'.' + varlist[i], 'hgvs')\n", - " if mapped == 'pre':\n", - " allele['location']['sequence_id'] = 'ga4gh:SQ.' + sha512t24u(ts.encode('ascii'))\n", - " allele['location']['interval']['start']['value'] = allele['location']['interval']['start']['value'] + offset\n", - " allele['location']['interval']['end']['value'] = allele['location']['interval']['end']['value'] + offset\n", - " allele['_id'] = ga4gh_identify(allele)\n", - " alleles.append(allele)\n", - " except:\n", - " vrstext = {'definition':ref + ':'+ l +'.' + varlist[i], 'type': 'Text'}\n", - " return vrstext\n", - " \n", - " if len(alleles) == 1: # Not haplotype\n", - " return alleles[0]\n", - " else:\n", - " return models.Haplotype(members = alleles)\n", + " mane_trans = mane.get_mane_from_transcripts(isect)\n", + " if mane_trans != []:\n", + " if len(mane_trans) == 1:\n", + " np = mane_trans[0]['RefSeq_prot']\n", + " else:\n", + " if mane_trans[0]['MANE_status'] == 'MANE Select':\n", + " np = mane_trans[0]['RefSeq_prot']\n", + " else:\n", + " np = mane_trans[1]['RefSeq_prot']\n", + " \n", + " oseq = dat.at[j, 'target_sequence']\n", + " \n", + " if len(set(str(oseq))) > 4:\n", + " stri = str(oseq)\n", + " else:\n", + " oseq = Seq(oseq)\n", + " stri = str(oseq.translate(table=1)).replace('*', '')\n", + " \n", + " if str(sr[np]).find(stri) != -1:\n", + " full_match = True\n", + " else:\n", + " full_match = False\n", + " start = str(sr[np]).find(stri[:10])\n", + " mappings_dict[dat.at[j,'urn']] = [np, start, dat.at[j, 'urn'], full_match]\n", + " \n", + " else:\n", + " trans_lens = []\n", + " for i in range(len(isect)):\n", + " trans_lens.append(len(str(sr[isect[i]])))\n", + " loc = trans_lens.index(max(trans_lens))\n", + " nm = isect[loc]\n", " \n", - "def get_clingen_id(hgvs):\n", - " url = 'https://reg.genome.network/allele?hgvs=' + hgvs\n", - " page = requests.get(url).json()\n", - " page = page['@id']\n", - " try:\n", - " return page.split('/')[4]\n", - " except:\n", - " return 'NA'" + " testquery = f\"SELECT pro_ac FROM uta_20210129.associated_accessions WHERE tx_ac = '{nm}'\"\n", + " async def np():\n", + " out = await utadb.execute_query(testquery)\n", + " try:\n", + " return out[0]['pro_ac']\n", + " except:\n", + " return out\n", + " np = asyncio.run(np())\n", + " \n", + " if np != []:\n", + " oseq = dat.at[j, 'target_sequence']\n", + " \n", + " if len(set(str(oseq))) > 4:\n", + " stri = str(oseq)\n", + " else:\n", + " oseq = Seq(oseq)\n", + " stri = str(oseq.translate(table=1)).replace('*', '')\n", + " \n", + " if str(sr[np]).find(stri) != -1:\n", + " full_match = True\n", + " else:\n", + " full_match = False\n", + " start = str(sr[np]).find(stri[:10])\n", + " mappings_dict[dat.at[j,'urn']] = [np, start, dat.at[j, 'urn'], full_match] \n", + "mappings_dict" ] }, { "cell_type": "code", - "execution_count": 14, - "id": "24d27355", + "execution_count": 16, + "id": "9a3cb7f1", "metadata": {}, "outputs": [ - { - "name": "stdout", - "output_type": "stream", - "text": [ - "***Using Gene Database Endpoint: http://localhost:8000***\n" - ] - }, { "name": "stderr", "output_type": "stream", "text": [ - "/Users/rsjxa001/.local/share/virtualenvs/dcd_mapping-l1Mz4xFf/lib/python3.8/site-packages/bs4/builder/__init__.py:545: XMLParsedAsHTMLWarning: It looks like you're parsing an XML document using an HTML parser. If this really is an HTML document (maybe it's XHTML?), you can ignore or filter this warning. If it's XML, you should know that using an XML parser will be more reliable. To parse this document as XML, make sure you have the lxml package installed, and pass the keyword argument `features=\"xml\"` into the BeautifulSoup constructor.\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n", + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", " warnings.warn(\n" ] - }, + } + ], + "source": [ + "# Find start location in provided target sequence when start position is not first position of sequence \n", + "import operator\n", + "offset_within_ts = {}\n", + "\n", + "def validation_helper(protstring):\n", + " protstring = protstring[1:][:-1]\n", + " vs = protstring.split(';')\n", + " return vs\n", + "\n", + "for i in range(len(mave_dat.index)):\n", + " if mave_dat.at[i, 'target_type'] == 'Protein coding' and mave_dat.at[i, 'target_sequence_type'] == 'dna':\n", + " urn = mave_dat.at[i, 'urn']\n", + " if urn == 'urn:mavedb:00000053-a-1' or urn == 'urn:mavedb:00000053-a-2': # target sequence missing codon\n", + " continue\n", + " oseq = Seq(mave_dat.at[i, 'target_sequence'])\n", + " ts = str(oseq.translate(table = 1))\n", + "\n", + " string = 'https://www.mavedb.org/scoreset/' + urn + '/scores/'\n", + " dat = requests.get(string).content\n", + " dat = pd.read_csv(io.StringIO(dat.decode('utf-8')), skiprows = 3, header = [1])\n", + "\n", + " protlist = dat['hgvs_pro'].to_list()\n", + " if type(dat.at[0, 'hgvs_pro']) != str or dat.at[0, 'hgvs_pro'].startswith('NP'):\n", + " continue\n", + " protlist = [x.lstrip('p.') for x in protlist]\n", + " \n", + " aa_dict = {}\n", + " for k in range(len(protlist)):\n", + " if protlist[k] == '_sy' or protlist[k] == '_wt':\n", + " continue\n", + " else:\n", + " if ';' in protlist[k]: \n", + " vs = validation_helper(protlist[k])\n", + " for l in range(len(vs)):\n", + " aa = vs[l][:3]\n", + " if aa == '=' or vs[l][-3:] not in Bio.SeqUtils.IUPACData.protein_letters_3to1.keys():\n", + " continue\n", + " if '=' in vs[l]:\n", + " loc = vs[l][3:][:-1]\n", + " else:\n", + " loc = vs[l][3:][:-3]\n", + " if loc not in aa_dict:\n", + " loc = re.sub('[^0-9]', '', loc)\n", + " aa_dict[loc] = seq1(aa)\n", + " \n", + " else:\n", + " if '_' in protlist[k]:\n", + " continue\n", + " aa = protlist[k][:3]\n", + " if aa == '=' or protlist[k][-3:] not in Bio.SeqUtils.IUPACData.protein_letters_3to1.keys():\n", + " continue\n", + " if '=' in protlist[k]:\n", + " loc = protlist[k][3:][:-1]\n", + " else:\n", + " loc = protlist[k][3:][:-3]\n", + " if loc not in aa_dict:\n", + " loc = re.sub('[^0-9]', '', loc)\n", + " aa_dict[loc] = seq1(aa)\n", + " \n", + "\n", + " aa_dict.pop('', None)\n", + " \n", + " err_locs = []\n", + " for m in range(len(ts)):\n", + " if str(m) in list(aa_dict.keys()):\n", + " if aa_dict[str(m)] != ts[int(m) - 1]: # Str vs dict offset\n", + " err_locs.append(m)\n", + " \n", + " if len(err_locs) > 1:\n", + " aa_dict = {int(k):v for k,v in aa_dict.items()}\n", + " aa_dict = sorted(aa_dict.items())\n", + " aa_dict = dict(aa_dict)\n", + " locs = list(aa_dict.keys())[0:5]\n", + " p0, p1, p2, p3, p4 = locs[0], locs[1], locs[2], locs[3], locs[4]\n", + " offset = locs[0]\n", + "\n", + " seq = ''\n", + " for key in aa_dict:\n", + " seq = seq + aa_dict[key]\n", + " \n", + " for i in range(len(ts)):\n", + " if ts[i] == aa_dict[p0] and ts[i + p1 - p0] == aa_dict[p1] and ts[i + p2 - p0] == aa_dict[p2] and ts[i + p3 - p0] == aa_dict[p3] and ts[i + p4 - p0] == aa_dict[p4]:\n", + " if i + 1 == min(aa_dict.keys()) or i + 2 == min(aa_dict.keys()):\n", + " offset_within_ts[urn] = 0\n", + " else:\n", + " offset_within_ts[urn] = i\n", + " break\n", + "\n", + "for key in offset_within_ts:\n", + " mappings_dict[key][1] = offset_within_ts[key]" + ] + }, + { + "cell_type": "code", + "execution_count": 18, + "id": "cfdad34c", + "metadata": {}, + "outputs": [ { "data": { "text/plain": [ @@ -3997,17 +6128,307 @@ " 269,\n", " 'urn:mavedb:00000041-a-1',\n", " True],\n", - " 'urn:mavedb:00000048-a-1': ['NP_003458.1',\n", + " 'urn:mavedb:00000048-a-1': ['NP_003458.1',\n", + " 0,\n", + " 'urn:mavedb:00000048-a-1',\n", + " True],\n", + " 'urn:mavedb:00000068-b-1': ['NP_000537.3',\n", + " 0,\n", + " 'urn:mavedb:00000068-b-1',\n", + " False],\n", + " 'urn:mavedb:00000045-c-1': 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'urn:mavedb:00000104-a-2': ['NP_001609.2',\n", + " -1,\n", + " 'urn:mavedb:00000104-a-2',\n", + " False],\n", + " 'urn:mavedb:00000005-a-6': ['NP_000062.1',\n", + " 0,\n", + " 'urn:mavedb:00000005-a-6',\n", + " True],\n", + " 'urn:mavedb:00000098-a-1': ['NP_000326.2',\n", + " 1619,\n", + " 'urn:mavedb:00000098-a-1',\n", + " True],\n", + " 'urn:mavedb:00000108-a-2': ['NP_000181.2',\n", + " 0,\n", + " 'urn:mavedb:00000108-a-2',\n", + " True],\n", + " 'urn:mavedb:00000001-a-4': ['NP_003336.1',\n", + " 0,\n", + " 'urn:mavedb:00000001-a-4',\n", + " True],\n", + " 'urn:mavedb:00000094-a-6': ['NP_004691.2',\n", + " 0,\n", + " 'urn:mavedb:00000094-a-6',\n", + " True],\n", + " 'urn:mavedb:00000078-a-1': ['NP_076869.1',\n", + " 0,\n", + " 'urn:mavedb:00000078-a-1',\n", + " True],\n", + " 'urn:mavedb:00000103-c-1': ['NP_002736.3',\n", + " 0,\n", + " 'urn:mavedb:00000103-c-1',\n", + " True],\n", + " 'urn:mavedb:00000043-a-1': ['NP_005364.1',\n", + " 486,\n", + " 'urn:mavedb:00000043-a-1',\n", + " 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'urn:mavedb:00000097-b-1': [],\n", + " 'urn:mavedb:00000097-k-1': [],\n", + " 'urn:mavedb:00000102-0-1': ['NP_000305.3',\n", + " 0,\n", + " 'urn:mavedb:00000102-0-1',\n", + " True],\n", + " 'urn:mavedb:00000001-b-2': ['NP_003343.1',\n", + " 0,\n", + " 'urn:mavedb:00000001-b-2',\n", + " True],\n", + " 'urn:mavedb:00000094-a-3': ['NP_004691.2',\n", + " 0,\n", + " 'urn:mavedb:00000094-a-3',\n", + " True],\n", + " 'urn:mavedb:00000061-g-1': ['NP_002871.1',\n", + " 51,\n", + " 'urn:mavedb:00000061-g-1',\n", + " True],\n", + " 'urn:mavedb:00000001-d-1': ['NP_071890.2',\n", + " 0,\n", + " 'urn:mavedb:00000001-d-1',\n", + " False],\n", + " 'urn:mavedb:00000097-p-1': [],\n", + " 'urn:mavedb:00000097-x-1': [],\n", + " 'urn:mavedb:00000055-a-1': ['NP_060753.1',\n", + " 0,\n", + " 'urn:mavedb:00000055-a-1',\n", + " True],\n", + " 'urn:mavedb:00000094-a-10': ['NP_004691.2',\n", + " 0,\n", + " 'urn:mavedb:00000094-a-10',\n", + " True],\n", + " 'urn:mavedb:00000045-i-1': ['NP_000336.1',\n", + " 0,\n", + " 'urn:mavedb:00000045-i-1',\n", + " True],\n", + " 'urn:mavedb:00000101-a-1': ['NP_000305.3',\n", + " 0,\n", + " 'urn:mavedb:00000101-a-1',\n", + " True],\n", + " 'urn:mavedb:00000053-a-1': ['NP_001308004.1',\n", + " 310,\n", + " 'urn:mavedb:00000053-a-1',\n", + " True],\n", + " 'urn:mavedb:00000097-v-1': [],\n", + " 'urn:mavedb:00000091-a-1': ['NP_004324.2',\n", + " 476,\n", + " 'urn:mavedb:00000091-a-1',\n", + " True],\n", + " 'urn:mavedb:00000048-c-1': ['NP_003458.1',\n", + " 0,\n", + " 'urn:mavedb:00000048-c-1',\n", + " True],\n", + " 'urn:mavedb:00000051-b-1': ['NP_004439.2',\n", + " 650,\n", + " 'urn:mavedb:00000051-b-1',\n", + " True],\n", + " 'urn:mavedb:00000097-m-1': [],\n", + " 'urn:mavedb:00000001-b-1': ['NP_003343.1',\n", + " 0,\n", + " 'urn:mavedb:00000001-b-1',\n", + " True],\n", + " 'urn:mavedb:00000103-a-1': ['NP_002736.3',\n", + " 0,\n", + " 'urn:mavedb:00000103-a-1',\n", + " True],\n", + " 'urn:mavedb:00000097-f-1': [],\n", + " 'urn:mavedb:00000057-b-1': ['NP_005334.1',\n", " 1,\n", - " 'urn:mavedb:00000048-a-1',\n", + " 'urn:mavedb:00000057-b-1',\n", " True],\n", - " 'urn:mavedb:00000068-b-1': ['NP_000537.3',\n", + " 'urn:mavedb:00000097-s-1': [],\n", + " 'urn:mavedb:00000045-f-1': ['NP_000336.1',\n", " 0,\n", - " 'urn:mavedb:00000068-b-1',\n", - " False],\n", - " 'urn:mavedb:00000045-c-1': ['NP_000336.1',\n", + " 'urn:mavedb:00000045-f-1',\n", + " True],\n", + " 'urn:mavedb:00000072-a-1': ['P01857', 223, 'urn:mavedb:00000072-a-1', True],\n", + " 'urn:mavedb:00000095-b-1': ['NP_000762.2',\n", " 0,\n", - " 'urn:mavedb:00000045-c-1',\n", + " 'urn:mavedb:00000095-b-1',\n", + " True],\n", + " 'urn:mavedb:00000001-a-1': ['NP_003336.1',\n", + " 0,\n", + " 'urn:mavedb:00000001-a-1',\n", " True],\n", " 'urn:mavedb:00000049-a-2': ['NP_005948.3',\n", " 0,\n", @@ -4033,26 +6454,10 @@ " 51,\n", " 'urn:mavedb:00000061-f-1',\n", " True],\n", - " 'urn:mavedb:00000001-c-1': ['NP_008819.1',\n", - " 0,\n", - " 'urn:mavedb:00000001-c-1',\n", - " True],\n", - " 'urn:mavedb:00000049-a-3': ['NP_005948.3',\n", - " 0,\n", - " 'urn:mavedb:00000049-a-3',\n", - " True],\n", " 'urn:mavedb:00000001-a-2': ['NP_003336.1',\n", " 0,\n", " 'urn:mavedb:00000001-a-2',\n", " True],\n", - " 'urn:mavedb:00000050-a-1': ['NP_000242.1',\n", - " 0,\n", - " 'urn:mavedb:00000050-a-1',\n", - " True],\n", - " 'urn:mavedb:00000061-i-1': ['NP_002871.1',\n", - " 51,\n", - " 'urn:mavedb:00000061-i-1',\n", - " True],\n", " 'urn:mavedb:00000003-b-2': ['NP_009225.1',\n", " 1,\n", " 'urn:mavedb:00000003-b-2',\n", @@ -4061,6 +6466,7 @@ " 2,\n", " 'urn:mavedb:00000062-a-1',\n", " True],\n", + " 'urn:mavedb:00000097-e-1': [],\n", " 'urn:mavedb:00000005-a-5': ['NP_000062.1',\n", " 0,\n", " 'urn:mavedb:00000005-a-5',\n", @@ -4069,10 +6475,6 @@ " 1,\n", " 'urn:mavedb:00000057-d-1',\n", " True],\n", - " 'urn:mavedb:00000094-a-5': ['NP_004691.2',\n", - " 0,\n", - " 'urn:mavedb:00000094-a-5',\n", - " True],\n", " 'urn:mavedb:00000068-a-1': ['NP_000537.3',\n", " 0,\n", " 'urn:mavedb:00000068-a-1',\n", @@ -4081,74 +6483,34 @@ " 0,\n", " 'urn:mavedb:00000049-a-6',\n", " True],\n", - " 'urn:mavedb:00000043-a-2': ['NP_005364.1',\n", - " 486,\n", - " 'urn:mavedb:00000043-a-2',\n", + " 'urn:mavedb:00000104-a-1': ['NP_001609.2',\n", + " -1,\n", + " 'urn:mavedb:00000104-a-1',\n", " False],\n", - " 'urn:mavedb:00000055-0-1': ['NP_060753.1',\n", - " 0,\n", - " 'urn:mavedb:00000055-0-1',\n", - " True],\n", - " 'urn:mavedb:00000005-a-6': ['NP_000062.1',\n", - " 0,\n", - " 'urn:mavedb:00000005-a-6',\n", - " True],\n", " 'urn:mavedb:00000049-a-1': ['NP_005948.3',\n", " 0,\n", " 'urn:mavedb:00000049-a-1',\n", " True],\n", - " 'urn:mavedb:00000001-a-4': ['NP_003336.1',\n", - " 0,\n", - " 'urn:mavedb:00000001-a-4',\n", - " True],\n", - " 'urn:mavedb:00000094-a-6': ['NP_004691.2',\n", - " 0,\n", - " 'urn:mavedb:00000094-a-6',\n", - " True],\n", - " 'urn:mavedb:00000078-a-1': ['NP_076869.1',\n", - " 0,\n", - " 'urn:mavedb:00000078-a-1',\n", - " True],\n", " 'urn:mavedb:00000013-b-1': ['NP_000358.1',\n", " 0,\n", " 'urn:mavedb:00000013-b-1',\n", " True],\n", - " 'urn:mavedb:00000043-a-1': ['NP_005364.1',\n", - " 486,\n", - " 'urn:mavedb:00000043-a-1',\n", - " True],\n", " 'urn:mavedb:00000093-a-1': ['NP_009225.1',\n", " 0,\n", " 'urn:mavedb:00000093-a-1',\n", " True],\n", - " 'urn:mavedb:00000061-d-1': ['NP_002871.1',\n", - " 51,\n", - " 'urn:mavedb:00000061-d-1',\n", - " True],\n", " 'urn:mavedb:00000001-a-3': ['NP_003336.1',\n", " 0,\n", " 'urn:mavedb:00000001-a-3',\n", " True],\n", - " 'urn:mavedb:00000046-a-1': ['NP_787058.5',\n", - " 243,\n", - " 'urn:mavedb:00000046-a-1',\n", - " True],\n", - " 'urn:mavedb:00000081-a-1': ['NP_009225.1',\n", - " 0,\n", - " 'urn:mavedb:00000081-a-1',\n", - " True],\n", - " 'urn:mavedb:00000067-a-1': ['NP_612510.1',\n", - " 0,\n", - " 'urn:mavedb:00000067-a-1',\n", - " True],\n", - " 'urn:mavedb:00000001-c-2': ['NP_008819.1',\n", - " 0,\n", - " 'urn:mavedb:00000001-c-2',\n", - " True],\n", " 'urn:mavedb:00000045-d-1': ['NP_000336.1',\n", " 0,\n", " 'urn:mavedb:00000045-d-1',\n", " True],\n", + " 'urn:mavedb:00000108-a-1': ['NP_000181.2',\n", + " 0,\n", + " 'urn:mavedb:00000108-a-1',\n", + " True],\n", " 'urn:mavedb:00000096-a-1': ['NP_000153.1',\n", " 0,\n", " 'urn:mavedb:00000096-a-1',\n", @@ -4157,38 +6519,21 @@ " 1,\n", " 'urn:mavedb:00000003-a-2',\n", " False],\n", - " 'urn:mavedb:00000049-a-7': ['NP_005948.3',\n", - " 0,\n", - " 'urn:mavedb:00000049-a-7',\n", - " True],\n", - " 'urn:mavedb:00000060-a-2': ['NP_031401.1',\n", - " 0,\n", - " 'urn:mavedb:00000060-a-2',\n", - " True],\n", - " 'urn:mavedb:00000058-a-1': ['NP_000475.1',\n", - " 671,\n", - " 'urn:mavedb:00000058-a-1',\n", - " True],\n", - " 'urn:mavedb:00000045-k-1': ['NP_000336.1',\n", - " 0,\n", - " 'urn:mavedb:00000045-k-1',\n", - " True],\n", - " 'urn:mavedb:00000094-a-14': ['NP_000209.2',\n", + " 'urn:mavedb:00000097-c-1': [],\n", + " 'urn:mavedb:00000106-a-1': ['NP_065712.1',\n", " 0,\n", - " 'urn:mavedb:00000094-a-14',\n", + " 'urn:mavedb:00000106-a-1',\n", " True],\n", " 'urn:mavedb:00000036-a-2': ['NP_056442.2',\n", " 0,\n", " 'urn:mavedb:00000036-a-2',\n", " False],\n", + " 'urn:mavedb:00000097-t-1': [],\n", + " 'urn:mavedb:00000097-l-1': [],\n", " 'urn:mavedb:00000094-a-11': ['NP_004691.2',\n", " 0,\n", " 'urn:mavedb:00000094-a-11',\n", " True],\n", - " 'urn:mavedb:00000069-a-2': ['NP_001358344.1',\n", - " 0,\n", - " 'urn:mavedb:00000069-a-2',\n", - " True],\n", " 'urn:mavedb:00000002-a-2': ['NP_001123617.1',\n", " 169,\n", " 'urn:mavedb:00000002-a-2',\n", @@ -4201,18 +6546,10 @@ " 0,\n", " 'urn:mavedb:00000035-a-2',\n", " True],\n", - " 'urn:mavedb:00000046-a-2': ['NP_787058.5',\n", - " 243,\n", - " 'urn:mavedb:00000046-a-2',\n", - " True],\n", " 'urn:mavedb:00000035-a-3': ['NP_000850.1',\n", " 0,\n", " 'urn:mavedb:00000035-a-3',\n", " True],\n", - " 'urn:mavedb:00000069-a-1': ['NP_001358344.1',\n", - " 0,\n", - " 'urn:mavedb:00000069-a-1',\n", - " True],\n", " 'urn:mavedb:00000094-a-13': ['NP_004691.2',\n", " 0,\n", " 'urn:mavedb:00000094-a-13',\n", @@ -4225,50 +6562,32 @@ " 93,\n", " 'urn:mavedb:00000051-c-1',\n", " True],\n", + " 'urn:mavedb:00000097-u-1': [],\n", + " 'urn:mavedb:00000097-d-1': [],\n", " 'urn:mavedb:00000036-a-1': ['NP_056442.2',\n", " 0,\n", " 'urn:mavedb:00000036-a-1',\n", " False],\n", - " 'urn:mavedb:00000049-a-8': ['NP_005948.3',\n", - " 0,\n", - " 'urn:mavedb:00000049-a-8',\n", - " True],\n", - " 'urn:mavedb:00000047-c-1': ['NP_000570.1',\n", - " 1,\n", - " 'urn:mavedb:00000047-c-1',\n", - " True],\n", - " 'urn:mavedb:00000094-a-8': ['NP_004691.2',\n", + " 'urn:mavedb:00000081-a-2': ['NP_009225.1',\n", " 0,\n", - " 'urn:mavedb:00000094-a-8',\n", - " True],\n", - " 'urn:mavedb:00000041-b-1': ['NP_938033.1',\n", - " 1,\n", - " 'urn:mavedb:00000041-b-1',\n", + " 'urn:mavedb:00000081-a-2',\n", " True],\n", " 'urn:mavedb:00000053-a-2': ['NP_001308004.1',\n", " 310,\n", " 'urn:mavedb:00000053-a-2',\n", " True],\n", - " 'urn:mavedb:00000045-a-1': ['NP_000336.1',\n", - " 0,\n", - " 'urn:mavedb:00000045-a-1',\n", - " True],\n", " 'urn:mavedb:00000060-a-1': ['NP_031401.1',\n", - " 0,\n", + " 289,\n", " 'urn:mavedb:00000060-a-1',\n", " True],\n", - " 'urn:mavedb:00000061-h-1': ['NP_002871.1',\n", - " 51,\n", - " 'urn:mavedb:00000061-h-1',\n", - " True],\n", " 'urn:mavedb:00000013-a-1': ['NP_000305.3',\n", " 0,\n", " 'urn:mavedb:00000013-a-1',\n", " True],\n", - " 'urn:mavedb:00000066-a-1': ['NP_001484.1',\n", - " 0,\n", - " 'urn:mavedb:00000066-a-1',\n", - " True],\n", + " 'urn:mavedb:00000097-z-1': ['NP_009225.1',\n", + " -1,\n", + " 'urn:mavedb:00000097-z-1',\n", + " False],\n", " 'urn:mavedb:00000094-a-9': ['NP_004691.2',\n", " 0,\n", " 'urn:mavedb:00000094-a-9',\n", @@ -4277,21 +6596,13 @@ " 0,\n", " 'urn:mavedb:00000045-e-1',\n", " True],\n", - " 'urn:mavedb:00000094-a-15': ['NP_000209.2',\n", - " 0,\n", - " 'urn:mavedb:00000094-a-15',\n", - " True],\n", - " 'urn:mavedb:00000094-a-2': ['NP_004691.2',\n", - " 0,\n", - " 'urn:mavedb:00000094-a-2',\n", - " True],\n", + " 'urn:mavedb:00000097-j-1': ['NP_009225.1',\n", + " 1630,\n", + " 'urn:mavedb:00000097-j-1',\n", + " False],\n", " 'urn:mavedb:00000047-b-1': ['NP_000570.1',\n", - " 1,\n", - " 'urn:mavedb:00000047-b-1',\n", - " True],\n", - " 'urn:mavedb:00000094-a-4': ['NP_004691.2',\n", " 0,\n", - " 'urn:mavedb:00000094-a-4',\n", + " 'urn:mavedb:00000047-b-1',\n", " True],\n", " 'urn:mavedb:00000003-b-1': ['NP_009225.1',\n", " 1,\n", @@ -4301,34 +6612,18 @@ " 0,\n", " 'urn:mavedb:00000054-a-1',\n", " True],\n", - " 'urn:mavedb:00000059-a-1': ['NP_000537.3',\n", - " 101,\n", - " 'urn:mavedb:00000059-a-1',\n", - " True],\n", " 'urn:mavedb:00000061-a-1': ['NP_002871.1',\n", " 51,\n", " 'urn:mavedb:00000061-a-1',\n", " True],\n", - " 'urn:mavedb:00000094-a-1': ['NP_004691.2',\n", - " 0,\n", - " 'urn:mavedb:00000094-a-1',\n", - " True],\n", " 'urn:mavedb:00000047-a-1': ['NP_000570.1',\n", - " 1,\n", - " 'urn:mavedb:00000047-a-1',\n", - " True],\n", - " 'urn:mavedb:00000045-g-1': ['NP_000336.1',\n", " 0,\n", - " 'urn:mavedb:00000045-g-1',\n", + " 'urn:mavedb:00000047-a-1',\n", " True],\n", " 'urn:mavedb:00000035-a-1': ['NP_000850.1',\n", " 0,\n", " 'urn:mavedb:00000035-a-1',\n", " True],\n", - " 'urn:mavedb:00000045-j-1': ['NP_000336.1',\n", - " 0,\n", - " 'urn:mavedb:00000045-j-1',\n", - " True],\n", " 'urn:mavedb:00000078-b-1': ['NP_076869.1',\n", " 0,\n", " 'urn:mavedb:00000078-b-1',\n", @@ -4345,10 +6640,6 @@ " 243,\n", " 'urn:mavedb:00000046-a-3',\n", " True],\n", - " 'urn:mavedb:00000049-a-4': ['NP_005948.3',\n", - " 0,\n", - " 'urn:mavedb:00000049-a-4',\n", - " True],\n", " 'urn:mavedb:00000068-c-1': ['NP_000537.3',\n", " 0,\n", " 'urn:mavedb:00000068-c-1',\n", @@ -4365,86 +6656,48 @@ " 0,\n", " 'urn:mavedb:00000055-b-1',\n", " True],\n", - " 'urn:mavedb:00000001-b-2': ['NP_003343.1',\n", - " 0,\n", - " 'urn:mavedb:00000001-b-2',\n", - " True],\n", - " 'urn:mavedb:00000094-a-3': ['NP_004691.2',\n", - " 0,\n", - " 'urn:mavedb:00000094-a-3',\n", - " True],\n", - " 'urn:mavedb:00000061-g-1': ['NP_002871.1',\n", - " 51,\n", - " 'urn:mavedb:00000061-g-1',\n", - " True],\n", - " 'urn:mavedb:00000001-d-1': ['NP_071890.2',\n", - " 0,\n", - " 'urn:mavedb:00000001-d-1',\n", - " False],\n", " 'urn:mavedb:00000057-a-1': ['NP_005334.1',\n", " 1,\n", " 'urn:mavedb:00000057-a-1',\n", " True],\n", - " 'urn:mavedb:00000055-a-1': ['NP_060753.1',\n", - " 0,\n", - " 'urn:mavedb:00000055-a-1',\n", - " True],\n", + " 'urn:mavedb:00000097-n-1': [],\n", " 'urn:mavedb:00000001-d-2': ['NP_071890.2',\n", " 0,\n", " 'urn:mavedb:00000001-d-2',\n", " False],\n", - " 'urn:mavedb:00000094-a-10': ['NP_004691.2',\n", - " 0,\n", - " 'urn:mavedb:00000094-a-10',\n", - " True],\n", " 'urn:mavedb:00000005-a-3': ['NP_000062.1',\n", " 0,\n", " 'urn:mavedb:00000005-a-3',\n", " True],\n", - " 'urn:mavedb:00000045-i-1': ['NP_000336.1',\n", - " 0,\n", - " 'urn:mavedb:00000045-i-1',\n", - " True],\n", - " 'urn:mavedb:00000053-a-1': ['NP_001308004.1',\n", - " 310,\n", - " 'urn:mavedb:00000053-a-1',\n", - " True],\n", - " 'urn:mavedb:00000091-a-1': ['NP_004324.2',\n", - " 476,\n", - " 'urn:mavedb:00000091-a-1',\n", - " True],\n", - " 'urn:mavedb:00000048-c-1': ['NP_003458.1',\n", - " 1,\n", - " 'urn:mavedb:00000048-c-1',\n", + " 'urn:mavedb:00000106-c-1': ['NP_065712.1',\n", + " 0,\n", + " 'urn:mavedb:00000106-c-1',\n", " True],\n", " 'urn:mavedb:00000045-b-1': ['NP_000336.1',\n", " 0,\n", " 'urn:mavedb:00000045-b-1',\n", " True],\n", " 'urn:mavedb:00000048-b-1': ['NP_003458.1',\n", - " 1,\n", + " 0,\n", " 'urn:mavedb:00000048-b-1',\n", " True],\n", " 'urn:mavedb:00000095-a-1': ['NP_000762.2',\n", " 0,\n", " 'urn:mavedb:00000095-a-1',\n", " True],\n", - " 'urn:mavedb:00000051-b-1': ['NP_004439.2',\n", - " 650,\n", - " 'urn:mavedb:00000051-b-1',\n", - " True],\n", " 'urn:mavedb:00000049-a-5': ['NP_005948.3',\n", " 0,\n", " 'urn:mavedb:00000049-a-5',\n", " True],\n", + " 'urn:mavedb:00000097-y-1': ['NP_009225.1',\n", + " -1,\n", + " 'urn:mavedb:00000097-y-1',\n", + " False],\n", " 'urn:mavedb:00000005-a-1': ['NP_000062.1',\n", " 0,\n", " 'urn:mavedb:00000005-a-1',\n", " True],\n", - " 'urn:mavedb:00000001-b-1': ['NP_003343.1',\n", - " 0,\n", - " 'urn:mavedb:00000001-b-1',\n", - " True],\n", + " 'urn:mavedb:00000097-a-1': [],\n", " 'urn:mavedb:00000003-a-1': ['NP_009225.1',\n", " 1,\n", " 'urn:mavedb:00000003-a-1',\n", @@ -4457,163 +6710,41 @@ " 169,\n", " 'urn:mavedb:00000002-a-1',\n", " True],\n", - " 'urn:mavedb:00000057-b-1': ['NP_005334.1',\n", - " 1,\n", - " 'urn:mavedb:00000057-b-1',\n", + " 'urn:mavedb:00000107-a-1': ['NP_478059.1',\n", + " 0,\n", + " 'urn:mavedb:00000107-a-1',\n", " True],\n", - " 'urn:mavedb:00000045-f-1': ['NP_000336.1',\n", + " 'urn:mavedb:00000103-d-1': ['NP_002736.3',\n", " 0,\n", - " 'urn:mavedb:00000045-f-1',\n", + " 'urn:mavedb:00000103-d-1',\n", " True],\n", - " 'urn:mavedb:00000072-a-1': ['P01857', 223, 'urn:mavedb:00000072-a-1', True],\n", " 'urn:mavedb:00000061-b-1': ['NP_002871.1',\n", " 51,\n", " 'urn:mavedb:00000061-b-1',\n", " True],\n", - " 'urn:mavedb:00000095-b-1': ['NP_000762.2',\n", - " 0,\n", - " 'urn:mavedb:00000095-b-1',\n", - " True],\n", - " 'urn:mavedb:00000001-a-1': ['NP_003336.1',\n", - " 0,\n", - " 'urn:mavedb:00000001-a-1',\n", - " True]}" + " 'urn:mavedb:00000097-q-1': []}" ] }, - "execution_count": 14, + "execution_count": 18, "metadata": {}, "output_type": "execute_result" } ], "source": [ - "## UTA Transcript Selection\n", - "nest_asyncio.apply()\n", - "mane = MANETranscriptMappings()\n", - "utadb = UTADatabase(db_pwd = 'uta')\n", - "qh = QueryHandler()\n", - "dp = SeqRepoDataProxy(sr = sr)\n", - "\n", - "mappings_dict = {}\n", - "\n", - "for j in range(len(dat.index)):\n", - " if dat.at[j, 'target_type'] == 'Protein coding':\n", - " item = mave_blat_dict[dat.at[j,'urn']]\n", - " #if blat_check(j) == False:\n", - " # mappings_dict[dat.at[j, 'urn']] = 'BLAT hit not found on correct chromosome'\n", - " # continue\n", - " if item['chrom'] == 'NA':\n", - " continue\n", - " locs = get_locs_list(item['hits'])\n", - " chrom = get_chr(dp, item['chrom'])\n", - "\n", - " try:\n", - " uniprot = dat.at[j, 'uniprot_id']\n", - " gsymb = qh.normalize(str(f'uniprot:{uniprot}')).gene_descriptor.label\n", - " except: \n", - " temp = dat.at[j, 'target'].split(' ')\n", - " gsymb = qh.normalize(temp[0]).gene_descriptor.label\n", - "\n", - " async def mapq():\n", - " transcript_lists = []\n", - " for i in range(len(locs)):\n", - " testquery = (f\"\"\"select *\n", - " from uta_20210129.tx_exon_aln_v\n", - " where hgnc = '{gsymb}'\n", - " and {locs[i][0]} between alt_start_i and alt_end_i\n", - " or {locs[i][1]} between alt_start_i and alt_end_i\n", - " and alt_ac = '{chrom}'\"\"\") \n", - " \n", - " out = await utadb.execute_query(testquery)\n", - " tl = []\n", - " for j in range(len(out)):\n", - " if out[j]['tx_ac'].startswith('NR_') == False:\n", - " tl.append(out[j]['tx_ac'])\n", - " if tl != []:\n", - " transcript_lists.append(tl)\n", - " return(transcript_lists)\n", - "\n", - " ts = asyncio.run(mapq())\n", - " try:\n", - " isect = list(set.intersection(*map(set,ts)))\n", - " except:\n", - " try: # Look for transcripts using uniprot id\n", - " url = 'https://www.uniprot.org/uniprot/' + str(dat.at[j, 'uniprot_id']) + '.xml'\n", - " page = requests.get(url)\n", - " page = BeautifulSoup(page.text)\n", - " page = page.find_all('sequence')\n", - " up = page[1].get_text()\n", - "\n", - " stri = str(dat.at[j,'target_sequence'])\n", - " if up.find(stri) != -1:\n", - " full_match = True\n", - " else:\n", - " full_match = False\n", - " start = up.find(stri[0:9])\n", - " mappings_dict[dat.at[j,'urn']] = [dat.at[j, 'uniprot_id'], start, dat.at[j, 'urn'], full_match]\n", - " continue\n", - " except:\n", - " print([dat.at[j, 'urn'], 'no transcripts found'])\n", - " continue\n", - "\n", - " mane_trans = mane.get_mane_from_transcripts(isect)\n", - " if mane_trans != []:\n", - " if len(mane_trans) == 1:\n", - " np = mane_trans[0]['RefSeq_prot']\n", - " else:\n", - " if mane_trans[0]['MANE_status'] == 'MANE Select':\n", - " np = mane_trans[0]['RefSeq_prot']\n", - " else:\n", - " np = mane_trans[1]['RefSeq_prot']\n", - " \n", - " oseq = dat.at[j, 'target_sequence']\n", - " \n", - " if len(set(str(oseq))) > 4:\n", - " stri = str(oseq)\n", - " else:\n", - " oseq = Seq(oseq)\n", - " stri = str(oseq.translate(table=1)).replace('*', '')\n", - " \n", - " if str(sr[np]).find(stri) != -1:\n", - " full_match = True\n", - " else:\n", - " full_match = False\n", - " start = str(sr[np]).find(stri[0:9])\n", - " mappings_dict[dat.at[j,'urn']] = [np, start, dat.at[j, 'urn'], full_match]\n", - " \n", - " else:\n", - " trans_lens = []\n", - " for i in range(len(isect)):\n", - " trans_lens.append(len(str(sr[isect[i]])))\n", - " loc = trans_lens.index(max(trans_lens))\n", - " nm = isect[loc]\n", - " \n", - " testquery = f\"SELECT pro_ac FROM uta_20210129.associated_accessions WHERE tx_ac = '{nm}'\"\n", - " async def np():\n", - " out = await utadb.execute_query(testquery)\n", - " try:\n", - " return out[0]['pro_ac']\n", - " except:\n", - " return out\n", - " np = asyncio.run(np())\n", - " \n", - " if np != []:\n", - " oseq = dat.at[j, 'target_sequence']\n", - " \n", - " if len(set(str(oseq))) > 4:\n", - " stri = str(oseq)\n", - " else:\n", - " oseq = Seq(oseq)\n", - " stri = str(oseq.translate(table=1)).replace('*', '')\n", - " \n", - " if str(sr[np]).find(stri) != -1:\n", - " full_match = True\n", - " else:\n", - " full_match = False\n", - " start = str(sr[np]).find(stri[0:9])\n", - " mappings_dict[dat.at[j,'urn']] = [np, start, dat.at[j, 'urn'], full_match] \n", "mappings_dict" ] }, + { + "cell_type": "code", + "execution_count": 17, + "id": "37a7890c", + "metadata": {}, + "outputs": [], + "source": [ + "with open('results/mappings.pickle', 'wb') as fn:\n", + " pickle.dump(mappings_dict, fn, protocol=pickle.HIGHEST_PROTOCOL)" + ] + }, { "cell_type": "markdown", "id": "17c59aa0", @@ -4624,7 +6755,21 @@ }, { "cell_type": "code", - "execution_count": 15, + "execution_count": 3, + "id": "f86c4681", + "metadata": {}, + "outputs": [], + "source": [ + "with open('results/mave_blat.pickle', 'rb') as fn:\n", + " mave_blat_dict = pickle.load(fn)\n", + " \n", + "with open('results/mappings.pickle', 'rb') as fn:\n", + " mappings_dict = pickle.load(fn)" + ] + }, + { + "cell_type": "code", + "execution_count": 4, "id": "b3d361bd", "metadata": {}, "outputs": [ @@ -4632,3479 +6777,5682 @@ "name": "stdout", "output_type": "stream", "text": [ - "***Using Gene Database Endpoint: http://localhost:8000***\n" + "***Using Gene Database Endpoint: http://localhost:8000***\n", + "urn:mavedb:00000041-a-1\n", + "urn:mavedb:00000048-a-1\n", + "urn:mavedb:00000068-b-1\n", + "urn:mavedb:00000045-c-1\n", + "urn:mavedb:00000099-a-1\n", + "urn:mavedb:00000001-c-1\n", + "urn:mavedb:00000049-a-3\n", + "urn:mavedb:00000050-a-1\n", + "urn:mavedb:00000061-i-1\n", + "urn:mavedb:00000094-a-5\n", + "urn:mavedb:00000043-a-2\n", + "urn:mavedb:00000055-0-1\n", + "urn:mavedb:00000104-a-2\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "urn:mavedb:00000005-a-6\n", + "urn:mavedb:00000098-a-1\n", + "urn:mavedb:00000108-a-2\n", + "urn:mavedb:00000001-a-4\n", + "urn:mavedb:00000094-a-6\n", + "urn:mavedb:00000078-a-1\n", + "urn:mavedb:00000103-c-1\n", + "urn:mavedb:00000043-a-1\n", + "urn:mavedb:00000061-d-1\n", + "urn:mavedb:00000046-a-1\n", + "urn:mavedb:00000081-a-1\n", + "urn:mavedb:00000097-r-1\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "urn:mavedb:00000067-a-1\n", + "urn:mavedb:00000001-c-2\n", + "urn:mavedb:00000049-a-7\n", + "urn:mavedb:00000060-a-2\n", + "urn:mavedb:00000058-a-1\n", + "urn:mavedb:00000045-k-1\n", + "urn:mavedb:00000094-a-14\n", + "urn:mavedb:00000069-a-2\n", + "urn:mavedb:00000106-b-1\n", + "urn:mavedb:00000046-a-2\n", + "urn:mavedb:00000069-a-1\n", + "urn:mavedb:00000049-a-8\n", + "urn:mavedb:00000047-c-1\n", + "urn:mavedb:00000094-a-8\n", + "urn:mavedb:00000041-b-1\n", + "urn:mavedb:00000097-o-1\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "urn:mavedb:00000045-a-1\n", + "urn:mavedb:00000097-0-1\n", + "urn:mavedb:00000097-h-1\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "urn:mavedb:00000061-h-1\n", + "urn:mavedb:00000066-a-1\n", + "urn:mavedb:00000108-a-3\n", + "urn:mavedb:00000094-a-15\n", + "urn:mavedb:00000094-a-2\n", + "urn:mavedb:00000094-a-4\n", + "urn:mavedb:00000059-a-1\n", + "urn:mavedb:00000094-a-1\n", + "urn:mavedb:00000045-g-1\n", + "urn:mavedb:00000097-i-1\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "urn:mavedb:00000097-w-1\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "urn:mavedb:00000045-j-1\n", + "urn:mavedb:00000103-b-1\n", + "urn:mavedb:00000097-g-1\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/Users/rsjxa001/.local/share/virtualenvs/analysis-WLxR8p6d/lib/python3.10/site-packages/Bio/Seq.py:3482: BiopythonWarning: Partial codon, len(sequence) not a multiple of three. Explicitly trim the sequence or add trailing N before translation. This may become an error in future.\n", + " warnings.warn(\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "urn:mavedb:00000049-a-4\n", + "urn:mavedb:00000097-b-1\n" ] }, { - "data": { - "text/plain": [ - "{'urn:mavedb:00000041-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.mEeUxPTsYR3nv2HatnR0fVPAN4wh... \n", - " 1 {'_id': 'ga4gh:VA.FXAraUEJO3xdWq83lg9L_XgSwkNK... \n", - " 2 {'_id': 'ga4gh:VA.FU1r-YnZOUngFiqwOjnttxkS_UWC... \n", - " 3 {'_id': 'ga4gh:VA.4IqIvzuRDc1_dbZERqoMcO2owJI_... \n", - " 4 {'_id': 'ga4gh:VA.mLrgCANFaxaL_w5H-HOqGOXxdHAN... \n", - " ... ... \n", - " 3501 {'_id': 'ga4gh:VA.J3C6cHm747Gel6jEHVuBFjq20jVd... \n", - " 3502 {'_id': 'ga4gh:VA.4cAPn_Ym9zeape35iStqIguN--7D... \n", - " 3503 {'_id': 'ga4gh:VA.-SRcbASnO6P-_eUyTkCbUU0ObSIu... \n", - " 3504 {'_id': 'ga4gh:VA.b9uqNCk5AoY2FOepvkpcPmTvUY0M... \n", - " 3505 {'_id': 'ga4gh:VA.Rfe-JmdXfDPA0EZzXPs-rFmiRRu-... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.NXnq2B9h0OLVbKfqGRoDLkf4Mqc0... \n", - 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" .. ... \n", - " 116 {'_id': 'ga4gh:VA.vDVoJkcwBUKFonGAKmpsx7zGeXgc... \n", - " 117 {'_id': 'ga4gh:VA.mjYft03aNux0EqjD-QK9Hw-KHDZi... \n", - " 118 {'_id': 'ga4gh:VA.7a9bQRo05VL8HqiLfs-_Wkh3enph... \n", - " 119 {'_id': 'ga4gh:VA.PiEfiCnLNSOOg-n0GCMiJrks-4tj... \n", - " 120 {'_id': 'ga4gh:VA.UOJELVKckhIgl2OS0EWW1xvSIFLj... \n", - " \n", - " [121 rows x 2 columns],\n", - " 'urn:mavedb:00000094-a-12': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.-pcjCCXTKLI85aEU_QOXBPbMpM1Z... \n", - " 1 {'_id': 'ga4gh:VA.WM_YPc7aV9wdgwIuLc6SUzAg-El_... \n", - " 2 {'_id': 'ga4gh:VA.A221adAyFECXuDpq5Uy3QQ2IRRmQ... \n", - " 3 {'_id': 'ga4gh:VA.sgAqv8p-qqy3cqBT1g1GqygV5z62... \n", - " 4 {'_id': 'ga4gh:VA.uhP28prWp3_8nXmbjPobsotDPI24... \n", - " 5 {'_id': 'ga4gh:VA.lNSdg_HZ-1Fwi7ZE_mJtvQyZCect... \n", - " 6 {'_id': 'ga4gh:VA.-MZ9RNMuMcP_RI3j1rPbk_ucakbF... \n", - " 7 {'_id': 'ga4gh:VA.rifLh3MMuC8vGbupstuxwF6m32j2... \n", - " 8 {'_id': 'ga4gh:VA.kARP3Mro9vgd16Yd1aU6KBE4xVb1... \n", - " 9 {'_id': 'ga4gh:VA.yDYfqFmBGEuTdZfMJTki_qVv8xPX... \n", - " 10 {'_id': 'ga4gh:VA.fgN-vvLXYF2NWlXYYGcBGZ-apD3E... \n", - " 11 {'_id': 'ga4gh:VA.WbLAZ2YycOL56tLCq_pFQ0tNyZ2f... \n", - " 12 {'_id': 'ga4gh:VA.U6qCyZ9-B__vUAH8jaF8jcjxZCmw... \n", - " 13 {'_id': 'ga4gh:VA.6CgKqFWbPJ1jsyacZVvnxeC1TTF3... \n", - " 14 {'_id': 'ga4gh:VA.8jrySzd9VqFnA0KhDOdCa9zDthro... \n", - " 15 {'_id': 'ga4gh:VA.mBnYh36eogOgi-hjLU2SIncSe0ni... \n", - " 16 {'_id': 'ga4gh:VA.re8FjaXRyycj2L_N1H7AofCWkyAa... \n", - " 17 {'_id': 'ga4gh:VA.CvJgabT4ChbUU9_Xt2C3hGG_3vuk... \n", - " 18 {'_id': 'ga4gh:VA.xJnPm67IJNXmRNfGnfEFbzBSP3XF... \n", - " 19 {'_id': 'ga4gh:VA.EbEENq5tIWYjgG3_3gGZxqlCDdKx... \n", - " 20 {'_id': 'ga4gh:VA.d_lprtLSdgbknwefMitzq1dbzU5e... \n", - " 21 {'_id': 'ga4gh:VA.MHWIL_ygi82zPzAUpcKY5uzf-Okv... \n", - " 22 {'_id': 'ga4gh:VA.SKSITMZ19cGk1-8FtmcTAaJS8Es2... \n", - " 23 {'_id': 'ga4gh:VA.KqxYFZ07NYM1YMZQ-sKXWXPycU47... \n", - " 24 {'_id': 'ga4gh:VA.Dw897hXUKAgOtIzzvkoGw-FnEqvE... \n", - " 25 {'_id': 'ga4gh:VA.TAxvWH5eZ7Rnwph1rkxb8A0IANtM... \n", - " 26 {'_id': 'ga4gh:VA.c_aPR9sTU45eCY5JuVmerN2mcRq4... \n", - " 27 {'_id': 'ga4gh:VA.TqB1_gDkP1fJuOw9GizZl6apze7M... \n", - " 28 {'_id': 'ga4gh:VA.-ooFOfzOIt49a6GbZ7FDZWMPQW0r... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.-pcjCCXTKLI85aEU_QOXBPbMpM1Z... \n", - " 1 {'_id': 'ga4gh:VA.WM_YPc7aV9wdgwIuLc6SUzAg-El_... \n", - " 2 {'_id': 'ga4gh:VA.A221adAyFECXuDpq5Uy3QQ2IRRmQ... \n", - " 3 {'_id': 'ga4gh:VA.sgAqv8p-qqy3cqBT1g1GqygV5z62... \n", - " 4 {'_id': 'ga4gh:VA.uhP28prWp3_8nXmbjPobsotDPI24... \n", - " 5 {'_id': 'ga4gh:VA.lNSdg_HZ-1Fwi7ZE_mJtvQyZCect... \n", - " 6 {'_id': 'ga4gh:VA.-MZ9RNMuMcP_RI3j1rPbk_ucakbF... \n", - " 7 {'_id': 'ga4gh:VA.rifLh3MMuC8vGbupstuxwF6m32j2... \n", - " 8 {'_id': 'ga4gh:VA.kARP3Mro9vgd16Yd1aU6KBE4xVb1... \n", - " 9 {'_id': 'ga4gh:VA.yDYfqFmBGEuTdZfMJTki_qVv8xPX... \n", - " 10 {'_id': 'ga4gh:VA.fgN-vvLXYF2NWlXYYGcBGZ-apD3E... \n", - " 11 {'_id': 'ga4gh:VA.WbLAZ2YycOL56tLCq_pFQ0tNyZ2f... \n", - " 12 {'_id': 'ga4gh:VA.U6qCyZ9-B__vUAH8jaF8jcjxZCmw... \n", - " 13 {'_id': 'ga4gh:VA.6CgKqFWbPJ1jsyacZVvnxeC1TTF3... \n", - " 14 {'_id': 'ga4gh:VA.8jrySzd9VqFnA0KhDOdCa9zDthro... \n", - " 15 {'_id': 'ga4gh:VA.mBnYh36eogOgi-hjLU2SIncSe0ni... \n", - " 16 {'_id': 'ga4gh:VA.re8FjaXRyycj2L_N1H7AofCWkyAa... \n", - " 17 {'_id': 'ga4gh:VA.CvJgabT4ChbUU9_Xt2C3hGG_3vuk... \n", - " 18 {'_id': 'ga4gh:VA.xJnPm67IJNXmRNfGnfEFbzBSP3XF... \n", - " 19 {'_id': 'ga4gh:VA.EbEENq5tIWYjgG3_3gGZxqlCDdKx... \n", - " 20 {'_id': 'ga4gh:VA.d_lprtLSdgbknwefMitzq1dbzU5e... \n", - " 21 {'_id': 'ga4gh:VA.MHWIL_ygi82zPzAUpcKY5uzf-Okv... \n", - " 22 {'_id': 'ga4gh:VA.SKSITMZ19cGk1-8FtmcTAaJS8Es2... \n", - " 23 {'_id': 'ga4gh:VA.KqxYFZ07NYM1YMZQ-sKXWXPycU47... \n", - " 24 {'_id': 'ga4gh:VA.Dw897hXUKAgOtIzzvkoGw-FnEqvE... \n", - " 25 {'_id': 'ga4gh:VA.TAxvWH5eZ7Rnwph1rkxb8A0IANtM... \n", - " 26 {'_id': 'ga4gh:VA.c_aPR9sTU45eCY5JuVmerN2mcRq4... \n", - " 27 {'_id': 'ga4gh:VA.TqB1_gDkP1fJuOw9GizZl6apze7M... \n", - " 28 {'_id': 'ga4gh:VA.-ooFOfzOIt49a6GbZ7FDZWMPQW0r... ,\n", - " 'urn:mavedb:00000057-c-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.JH_qV-_9-ED4c9TO756XO2t1wybz... \n", - " 1 {'_id': 'ga4gh:VA.mHTikzGXkVcVuja1Cm5IAYCqC9Ha... \n", - " 2 {'_id': 'ga4gh:VA.dnUQg_3jD85tH3d_ru_olHYo0jke... \n", - " 3 {'_id': 'ga4gh:VA.JvUKP8vch4gIjlLRqWDPpCkKyJlq... \n", - " 4 {'_id': 'ga4gh:VA.DKQnVE4Ia3GkipXxZA0pTgSpQbmh... \n", - " ... ... \n", - " 3295 {'_id': 'ga4gh:VA.fAJqqW_Apv_2fzfRxrMnEk8cL8Si... \n", - " 3296 {'_id': 'ga4gh:VA.GtCcd5tjO5Wk0P0HPSgNo5aRDF-4... \n", - " 3297 {'_id': 'ga4gh:VA.guIQ6k4Hh4uz9AJfLhbdRUuUlvcc... \n", - " 3298 {'_id': 'ga4gh:VA.-CRqRSOUjzw0kQSs7j_RH2RTPDU_... \n", - " 3299 {'_id': 'ga4gh:VA.QKMAmGaA0ywaeyt8Chfq0jt1OCrz... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.-Oy_pcXpTYO-ofnNJJJH3_OgBVap... \n", - " 1 {'_id': 'ga4gh:VA.15DGh44KNnwam_1nuzOXfWlEjl1F... \n", - " 2 {'_id': 'ga4gh:VA.x3iHjACLPjtYYvEO3I0iFL7DTMp7... \n", - " 3 {'_id': 'ga4gh:VA.nJclz7QL-L6Z7RcE8lLPqFALSo_-... \n", - " 4 {'_id': 'ga4gh:VA.6R0o-ZjU0ZAbRmK4a1yYQSZWItEt... \n", - " ... ... \n", - " 3295 {'_id': 'ga4gh:VA.39C5F8lNQ-7lwPVRPD1jiddrTuxK... \n", - " 3296 {'_id': 'ga4gh:VA._crplVVMbmutmzCuMpUY8gzTpEYi... \n", - " 3297 {'_id': 'ga4gh:VA.SWvRkxuC_7a0hPbzzAVUyTkVX2Rc... \n", - " 3298 {'_id': 'ga4gh:VA.LFUb0B8ou-6GMHDVzYT9EUi9iw8h... \n", - " 3299 {'_id': 'ga4gh:VA.-JY7PRsipUMZ7pbURJ3Lu5ZJZ64C... \n", - " \n", - " [3300 rows x 2 columns],\n", - " 'urn:mavedb:00000094-a-7': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.1I94VC5u62-yCNxdtIN9iZfPoi9a... \n", - " 1 {'_id': 'ga4gh:VA.ZnKbt_R0NzwHM78PtKKRvng1UuES... \n", - " 2 {'_id': 'ga4gh:VA.tjX4SVcN7Vy3QKNebOoJA2Jpm4wu... \n", - " 3 {'_id': 'ga4gh:VA.XqOaxLWDNiLELe8CIMP6fJ2m6AYA... \n", - " 4 {'_id': 'ga4gh:VA.6voO1ip5CdZCx3WMMfQUHPWviChL... \n", - " .. ... \n", - " 148 {'_id': 'ga4gh:VA.6-BF1T9Glqd-lYvEk_43y9_5Uzz3... \n", - " 149 {'_id': 'ga4gh:VA.zKAQs5XABlbh0HlKnjmLfrFokdN0... \n", - " 150 {'_id': 'ga4gh:VA.mXzK1oHgKbZ1AIotE_DyqEfWSIfw... \n", - " 151 {'_id': 'ga4gh:VA.yFYBsjEzbaNVy4N93PFTbl1txiNi... \n", - " 152 {'_id': 'ga4gh:VA.XjB1HLjGDd0jfIGt1Lz8vH_EiROl... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.1I94VC5u62-yCNxdtIN9iZfPoi9a... \n", - " 1 {'_id': 'ga4gh:VA.ZnKbt_R0NzwHM78PtKKRvng1UuES... \n", - " 2 {'_id': 'ga4gh:VA.tjX4SVcN7Vy3QKNebOoJA2Jpm4wu... \n", - " 3 {'_id': 'ga4gh:VA.XqOaxLWDNiLELe8CIMP6fJ2m6AYA... \n", - " 4 {'_id': 'ga4gh:VA.6voO1ip5CdZCx3WMMfQUHPWviChL... \n", - " .. ... \n", - " 148 {'_id': 'ga4gh:VA.6-BF1T9Glqd-lYvEk_43y9_5Uzz3... \n", - " 149 {'_id': 'ga4gh:VA.zKAQs5XABlbh0HlKnjmLfrFokdN0... \n", - " 150 {'_id': 'ga4gh:VA.mXzK1oHgKbZ1AIotE_DyqEfWSIfw... \n", - " 151 {'_id': 'ga4gh:VA.yFYBsjEzbaNVy4N93PFTbl1txiNi... \n", - " 152 {'_id': 'ga4gh:VA.XjB1HLjGDd0jfIGt1Lz8vH_EiROl... \n", - " \n", - " [153 rows x 2 columns],\n", - " 'urn:mavedb:00000061-f-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA._8KwsU3sY4BypgOHjsCe5TMi3RMK... \n", - " 1 {'_id': 'ga4gh:VA.vYcda-pX5hAyJA9kdsYV2a6qSCG5... \n", - " 2 {'_id': 'ga4gh:VA.8Q7MJ9teWYApwn3n-ibDM9YUKP6j... \n", - " 3 {'_id': 'ga4gh:VA.L9S0vh6aEt3IJrD6ldxO_y5RIygU... \n", - " 4 {'_id': 'ga4gh:VA.wK4QQrCDGpEjI4K24VQWfzRlxTP7... \n", - " .. ... \n", - " 292 {'_id': 'ga4gh:VA.E8eUuddsO-lgh5_pfq69ja4Yga7F... \n", - " 293 {'_id': 'ga4gh:VA.-ZJ6-e9_JUBQVWDCIGhD1_q6Aawk... \n", - " 294 {'_id': 'ga4gh:VA.N6DMjFFZWVBFXtIfxJTJl_MULjYJ... \n", - " 295 {'_id': 'ga4gh:VA.0eJe4CyGplhRDB58l1g3CZJTun8n... \n", - " 296 {'_id': 'ga4gh:VA.HDwRxLsfSCCAhWdxgK_cftpzHBo3... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.kbwbTQQeuDIS-JlPQ-FikXijh2uC... \n", - " 1 {'_id': 'ga4gh:VA.es-nmUGhn9Gtg8pMw6dArUDjuKAc... \n", - " 2 {'_id': 'ga4gh:VA.RfxPfsu0xrJJmY-lQieuPRMSXAdt... \n", - " 3 {'_id': 'ga4gh:VA.UfdAl4Vf2Oz4s9QZI0dLULFoocrr... \n", - " 4 {'_id': 'ga4gh:VA.iSx0Xz6ZMpzTJZwrm_cXn3gQQu4M... \n", - " .. ... \n", - " 292 {'_id': 'ga4gh:VA.bq2ZT7YXkeMmwcokNwbnIh_yDq-Z... \n", - " 293 {'_id': 'ga4gh:VA.Q2Qcb1H9vc8IxHN5JhBsAaQe1PzT... \n", - " 294 {'_id': 'ga4gh:VA.p_KrLKauVGMz3USpZWI4lpk4ZOUr... \n", - " 295 {'_id': 'ga4gh:VA.geXsqQFPltdY2tniCRUPGs-7slRo... \n", - " 296 {'_id': 'ga4gh:VA.CYCkON8FBCk_GveRUNvBpun0jd_7... \n", - " \n", - " [297 rows x 2 columns],\n", - " 'urn:mavedb:00000001-c-1': pre_mapping \\\n", - 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This may become an error in future.\n", + " warnings.warn(\n" + ] + }, + { + "data": { + "text/plain": [ + "{'urn:mavedb:00000041-a-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.K7JuB0HAfN875G9YyQvnjWCH1STCY... \n", + " 1 {'id': 'ga4gh:VA.14HDZPvvZuCWWhT_OhE-Yvvc89gvk... \n", + " 2 {'id': 'ga4gh:VA._wx37BU-VVTbvg0zWgwp2Ym55iMVb... \n", + " 3 {'id': 'ga4gh:VA.EcsLmgd4pHc1uejRP34CxQ0setRif... \n", + " 4 {'id': 'ga4gh:VA.AsE39Yu8GinT0QVRkC8cs486_m68C... \n", + " ... ... \n", + " 3501 {'id': 'ga4gh:VA.AjXbF7b5sjQwteZlMKSmabYsqJHvB... \n", + " 3502 {'id': 'ga4gh:VA.vL2mlC4h7ZTEcJML6XY8LQGmc6Ph6... \n", + " 3503 {'id': 'ga4gh:VA.i4aHKTjGaCqm82v_sAbhJqi_pJ5o7... \n", + " 3504 {'id': 'ga4gh:VA.dVXd7aZ85GIcK0mLQ2eYqcIyE7EO0... \n", + " 3505 {'id': 'ga4gh:VA.-MzSTq_-YLGQs2Fw-0Ia9Sc-UMcp0... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.sDvBfCFBq2mUl7bL0D5ycHC3jNFg... \n", - " 1 {'_id': 'ga4gh:VA.GqFWnxf_zdaSeVQs6RM2Elbh9T19... \n", - " 2 {'_id': 'ga4gh:VA.jt0yzpCqrwQy8MSVBs2Lw-dFVzOE... 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\\\n", + " 0 {'id': 'ga4gh:VA.nYGssfca5mqtSWUFdSbkRt8ykMV16... \n", + " 1 {'id': 'ga4gh:VA.MkNOw2X3c1r8a7aKNvGDVao8Ksok1... \n", + " 2 {'id': 'ga4gh:VA.X16jwotZGu99Bb-2z0pFbfshtnLct... \n", + " 3 {'id': 'ga4gh:VA.Su1x6cPyWs9C2CimKJxATdDXPQISP... \n", + " 4 {'id': 'ga4gh:VA.SOpdi5QFExOmsUQ_MEXNBnG0bPwKj... \n", + " ... ... \n", + " 13685 {'id': 'ga4gh:VA.F5_5Dh6GwTkXbZ21Z7-7S-QMNBIPl... \n", + " 13686 {'id': 'ga4gh:VA.1BtFIFYr80MlByN-lI3DyrQkB84yD... \n", + " 13687 {'id': 'ga4gh:VA.mhvXRaaiSQR4D2SAyWEMdqcE7Mw0x... \n", + " 13688 {'id': 'ga4gh:VA.jeHGpx-9kmg2V90F0w-b1YQCa8yxT... \n", + " 13689 {'id': 'ga4gh:VA.Nvsc75_pVPMuOXNJEuJfqWAc_TlCt... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.nYGssfca5mqtSWUFdSbkRt8ykMV16... \n", + " 1 {'id': 'ga4gh:VA.MkNOw2X3c1r8a7aKNvGDVao8Ksok1... \n", + " 2 {'id': 'ga4gh:VA.X16jwotZGu99Bb-2z0pFbfshtnLct... \n", + " 3 {'id': 'ga4gh:VA.Su1x6cPyWs9C2CimKJxATdDXPQISP... \n", + " 4 {'id': 'ga4gh:VA.SOpdi5QFExOmsUQ_MEXNBnG0bPwKj... \n", + " ... ... \n", + " 13685 {'id': 'ga4gh:VA.F5_5Dh6GwTkXbZ21Z7-7S-QMNBIPl... \n", + " 13686 {'id': 'ga4gh:VA.1BtFIFYr80MlByN-lI3DyrQkB84yD... \n", + " 13687 {'id': 'ga4gh:VA.mhvXRaaiSQR4D2SAyWEMdqcE7Mw0x... \n", + " 13688 {'id': 'ga4gh:VA.jeHGpx-9kmg2V90F0w-b1YQCa8yxT... \n", + " 13689 {'id': 'ga4gh:VA.Nvsc75_pVPMuOXNJEuJfqWAc_TlCt... \n", + " \n", + " [13690 rows x 2 columns]],\n", + " 'urn:mavedb:00000050-a-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.4QuOadZ5Vsm9cT1NF6Qmu3qrr2RZw... \n", + " 1 {'id': 'ga4gh:VA.8vXDjuVv3ladwIJKHdFxTYqHz36x3... \n", + " 2 {'id': 'ga4gh:VA.AT_fY1w20A7_KwFjhH0_Wl9E2pSn2... \n", + " 3 {'id': 'ga4gh:VA.M9o8iexsNCT2LX0aSGWMYLDDYeBI4... \n", + " 4 {'id': 'ga4gh:VA.xtK09VyrtG3WQ0lVKwYa5ZGTDpdL6... \n", + " ... ... \n", + " 17741 {'id': 'ga4gh:VA.5gnRFrJlR5D7jgB9rinD4Xpk62a3g... \n", + " 17742 {'id': 'ga4gh:VA.motnAAOQ9A2ZuT-09qwgaBXYRS52P... \n", + " 17743 {'id': 'ga4gh:VA.09iMuzhRZ5d_Fd5mRBrVXeGCT-C2A... \n", + " 17744 {'id': 'ga4gh:VA.XwnuFhbDwwybXkkkAs1Foa9qWzGgi... \n", + " 17745 {'id': 'ga4gh:VA.piAZ2qIqY38IhnuUNDtqegvxe9ehH... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.4QuOadZ5Vsm9cT1NF6Qmu3qrr2RZw... \n", + " 1 {'id': 'ga4gh:VA.8vXDjuVv3ladwIJKHdFxTYqHz36x3... \n", + " 2 {'id': 'ga4gh:VA.AT_fY1w20A7_KwFjhH0_Wl9E2pSn2... \n", + " 3 {'id': 'ga4gh:VA.M9o8iexsNCT2LX0aSGWMYLDDYeBI4... \n", + " 4 {'id': 'ga4gh:VA.xtK09VyrtG3WQ0lVKwYa5ZGTDpdL6... \n", + " ... ... \n", + " 17741 {'id': 'ga4gh:VA.5gnRFrJlR5D7jgB9rinD4Xpk62a3g... \n", + " 17742 {'id': 'ga4gh:VA.motnAAOQ9A2ZuT-09qwgaBXYRS52P... \n", + " 17743 {'id': 'ga4gh:VA.09iMuzhRZ5d_Fd5mRBrVXeGCT-C2A... \n", + " 17744 {'id': 'ga4gh:VA.XwnuFhbDwwybXkkkAs1Foa9qWzGgi... \n", + " 17745 {'id': 'ga4gh:VA.piAZ2qIqY38IhnuUNDtqegvxe9ehH... \n", + " \n", + " [17746 rows x 2 columns]],\n", + " 'urn:mavedb:00000061-i-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.0JLYvO-oKusafaf3UC8JT8tmTjvNO... \n", + " 1 {'id': 'ga4gh:VA.Z_Rq47uT6cXhDUBDRhVkDDDsjBRs_... \n", + " 2 {'id': 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'ga4gh:VA.vfhVKJ_8HZCOlbCtQ_GhrsQ7zVBs... \n", - " 1963 {'_id': 'ga4gh:VA.syMKQClJOHozNkvhquHgDH9cuvbJ... \n", - " 1964 {'_id': 'ga4gh:VA.syMKQClJOHozNkvhquHgDH9cuvbJ... \n", - " \n", - " [1965 rows x 2 columns],\n", - " 'urn:mavedb:00000055-0-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.YidvVb77TcjaW1COdmYGDMK-M4j0... \n", - " 1 {'_id': 'ga4gh:VA.w8xjASY5yYRNvHNWXVCPu9Gk5z8W... \n", - " 2 {'_id': 'ga4gh:VA.gbASN2U3g2k7ocITm5k-VmzcSyKW... \n", - " 3 {'_id': 'ga4gh:VA.9Zp63mK9rxKsSUlpHLu6eJcgrJ0w... \n", - " 4 {'_id': 'ga4gh:VA.qpOZaWqNGPfRSkZK4BpEfIxSksJJ... \n", - " ... ... \n", - " 3009 {'_id': 'ga4gh:VA.at35Qbi3bB7lbqFs5tPw5aMZ0JH5... \n", - " 3010 {'_id': 'ga4gh:VA.E-_x3_dqKmJSBK3Qjm5MOQ0JpEdG... \n", - " 3011 {'_id': 'ga4gh:VA.DdyEZbZl-Ggx9YebFp6NavfH-Xwp... \n", - " 3012 {'_id': 'ga4gh:VA.hzFrWtBiW-FtoXMYRBpi3zI3bpq6... \n", - " 3013 {'_id': 'ga4gh:VA.YVUrbRpI9Naddy2BzI7Qh4bqNx-7... \n", - " \n", + " 0 {'id': 'ga4gh:VA.TaqdL9WrLoRrHnfMGJshPWd-nN7kQ... \n", + " 1 {'id': 'ga4gh:VA.ZqjF-YzQFca6iJzmbyds6hokjdFb9... \n", + " 2 {'id': 'ga4gh:VA.NKAc1WbfH3fXayWT8A0h8z-8nWNrV... \n", + " 3 {'id': 'ga4gh:VA.wmFW49-H75N-tldH64-4emr3rhlF0... \n", + " 4 {'id': 'ga4gh:VA.WBegm08BNrk7qNu-FoEdL7doQT4Pu... \n", + " .. ... \n", + " 292 {'id': 'ga4gh:VA.NMeqSijprMU0ZfggEDnVMpMs87Sbx... \n", + " 293 {'id': 'ga4gh:VA.rG1l--AEwLbCmCwHcJCQxm-C_k0-7... \n", + " 294 {'id': 'ga4gh:VA.PNwPiJzGqVwDrCNtzHn2e9a8o8HM8... \n", + " 295 {'id': 'ga4gh:VA.-Udu9WpLxl8nmU1WM2PhDVJDQ3nQT... \n", + " 296 {'id': 'ga4gh:VA.EGgncAidr2i_sUTRYJqO4ZySyG9D-... \n", + " \n", + " [297 rows x 2 columns]],\n", + " 'urn:mavedb:00000094-a-5': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.AAtdtl6-VdhvWGK-JuCaT716B2ZN0... \n", + " 1 {'id': 'ga4gh:VA.NAwQcw1UmXX7BA1kfm8sf3injekGr... \n", + " 2 {'id': 'ga4gh:VA.BiuVCc080nqjKlvZX2MsUGdTUW8PB... \n", + " 3 {'id': 'ga4gh:VA.8sCTw148ZkBDFMdcxh4KsCo6vlUNM... \n", + " 4 {'id': 'ga4gh:VA.QIxWliSei8e6uPPh4c9qX71C_cEUE... \n", + " .. ... \n", + " 910 {'id': 'ga4gh:VA.NihSI1ibNHM8kJqw-UNwe2J0-eOFc... \n", + " 911 {'id': 'ga4gh:VA.btHKqeve_lfGe8vf_9_CuyCCdMwQv... \n", + " 912 {'id': 'ga4gh:VA.HGi01HpwsqrDUdkr_rcqL0uFpSyEi... \n", + " 913 {'id': 'ga4gh:VA.L0dTPFM8yLmfD5oZfDtvkH51xlp4H... \n", + " 914 {'id': 'ga4gh:VA.iLL2NI9e9dV9TOhU7FEvKCo57oT3K... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.YidvVb77TcjaW1COdmYGDMK-M4j0... \n", - " 1 {'_id': 'ga4gh:VA.w8xjASY5yYRNvHNWXVCPu9Gk5z8W... \n", - " 2 {'_id': 'ga4gh:VA.gbASN2U3g2k7ocITm5k-VmzcSyKW... \n", - " 3 {'_id': 'ga4gh:VA.9Zp63mK9rxKsSUlpHLu6eJcgrJ0w... \n", - " 4 {'_id': 'ga4gh:VA.qpOZaWqNGPfRSkZK4BpEfIxSksJJ... \n", - " ... ... \n", - " 3009 {'_id': 'ga4gh:VA.at35Qbi3bB7lbqFs5tPw5aMZ0JH5... \n", - " 3010 {'_id': 'ga4gh:VA.E-_x3_dqKmJSBK3Qjm5MOQ0JpEdG... \n", - " 3011 {'_id': 'ga4gh:VA.DdyEZbZl-Ggx9YebFp6NavfH-Xwp... \n", - " 3012 {'_id': 'ga4gh:VA.hzFrWtBiW-FtoXMYRBpi3zI3bpq6... \n", - " 3013 {'_id': 'ga4gh:VA.YVUrbRpI9Naddy2BzI7Qh4bqNx-7... \n", - " \n", - " [3014 rows x 2 columns],\n", - " 'urn:mavedb:00000005-a-6': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.4w3sR9ptToy5O9aAUaA0jCD5FlKp... \n", - " 1 {'_id': 'ga4gh:VA.VO6KjDCN_t9rj11SwpOwjf86Kxoq... \n", - " 2 {'_id': 'ga4gh:VA.YT8CLWfzUCYiTjW4uoFWZOMVqb7X... \n", - " 3 {'_id': 'ga4gh:VA.YT8CLWfzUCYiTjW4uoFWZOMVqb7X... \n", - " 4 {'_id': 'ga4gh:VA.YT8CLWfzUCYiTjW4uoFWZOMVqb7X... \n", - " ... ... \n", - " 10797 {'_id': 'ga4gh:VA.e5On7rzdv_uGC7Vm4kzahHeKUmOz... \n", - " 10798 {'_id': 'ga4gh:VA.-QOqvkPk7FTuSuax9DYqCQtWydNe... \n", - " 10799 {'_id': 'ga4gh:VA.JW1NfIBzBJ0QqhkUCi_JEbO8xQye... \n", - " 10800 {'_id': 'ga4gh:VA.gQzF1GiKx6BkTzyQ3fr3VTGFcIDX... \n", - " 10801 {'_id': 'ga4gh:VA.P6owh9pg9i_liGjZX9xx5Zu7gows... \n", - " \n", + " 0 {'id': 'ga4gh:VA.AAtdtl6-VdhvWGK-JuCaT716B2ZN0... \n", + " 1 {'id': 'ga4gh:VA.NAwQcw1UmXX7BA1kfm8sf3injekGr... \n", + " 2 {'id': 'ga4gh:VA.BiuVCc080nqjKlvZX2MsUGdTUW8PB... \n", + " 3 {'id': 'ga4gh:VA.8sCTw148ZkBDFMdcxh4KsCo6vlUNM... \n", + " 4 {'id': 'ga4gh:VA.QIxWliSei8e6uPPh4c9qX71C_cEUE... \n", + " .. ... \n", + " 910 {'id': 'ga4gh:VA.NihSI1ibNHM8kJqw-UNwe2J0-eOFc... \n", + " 911 {'id': 'ga4gh:VA.btHKqeve_lfGe8vf_9_CuyCCdMwQv... \n", + " 912 {'id': 'ga4gh:VA.HGi01HpwsqrDUdkr_rcqL0uFpSyEi... \n", + " 913 {'id': 'ga4gh:VA.L0dTPFM8yLmfD5oZfDtvkH51xlp4H... \n", + " 914 {'id': 'ga4gh:VA.iLL2NI9e9dV9TOhU7FEvKCo57oT3K... \n", + " \n", + " [915 rows x 2 columns]],\n", + " 'urn:mavedb:00000043-a-2': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.Jp3JojhKbTGkghs6TzqJpVzClD-D2... \n", + " 1 {'id': 'ga4gh:VA.Jp3JojhKbTGkghs6TzqJpVzClD-D2... \n", + " 2 {'id': 'ga4gh:VA.Jp3JojhKbTGkghs6TzqJpVzClD-D2... \n", + " 3 {'id': 'ga4gh:VA.Jp3JojhKbTGkghs6TzqJpVzClD-D2... \n", + " 4 {'id': 'ga4gh:VA.79Xi07J717gm5EDvigz_SfPIG1Nco... \n", + " ... ... \n", + " 1960 {'id': 'ga4gh:VA.nPLQcJLGtuk3VICo7JCvCw5irEWtw... \n", + " 1961 {'id': 'ga4gh:VA.XrjwI8P2W2ZCitwlpcl41gEy540AP... \n", + " 1962 {'id': 'ga4gh:VA.XrjwI8P2W2ZCitwlpcl41gEy540AP... \n", + " 1963 {'id': 'ga4gh:VA.1SfE6bRx3IhtSHjKezpYkC_Yp8b2S... \n", + " 1964 {'id': 'ga4gh:VA.1SfE6bRx3IhtSHjKezpYkC_Yp8b2S... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.4w3sR9ptToy5O9aAUaA0jCD5FlKp... \n", - " 1 {'_id': 'ga4gh:VA.VO6KjDCN_t9rj11SwpOwjf86Kxoq... \n", - " 2 {'_id': 'ga4gh:VA.YT8CLWfzUCYiTjW4uoFWZOMVqb7X... \n", - " 3 {'_id': 'ga4gh:VA.YT8CLWfzUCYiTjW4uoFWZOMVqb7X... \n", - " 4 {'_id': 'ga4gh:VA.YT8CLWfzUCYiTjW4uoFWZOMVqb7X... \n", - " ... ... \n", - " 10797 {'_id': 'ga4gh:VA.e5On7rzdv_uGC7Vm4kzahHeKUmOz... \n", - " 10798 {'_id': 'ga4gh:VA.-QOqvkPk7FTuSuax9DYqCQtWydNe... \n", - " 10799 {'_id': 'ga4gh:VA.JW1NfIBzBJ0QqhkUCi_JEbO8xQye... \n", - " 10800 {'_id': 'ga4gh:VA.gQzF1GiKx6BkTzyQ3fr3VTGFcIDX... \n", - " 10801 {'_id': 'ga4gh:VA.P6owh9pg9i_liGjZX9xx5Zu7gows... \n", - " \n", - " [10802 rows x 2 columns],\n", - " 'urn:mavedb:00000049-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.geIkNDd-9WbvUyORdGetgadmWXXk... \n", - " 1 {'_id': 'ga4gh:VA.U4CznAWPCpr33nMHOCYHjvsqV-bf... \n", - " 2 {'_id': 'ga4gh:VA.oW5MjBcA2Xay7COb5Rsd06esot31... \n", - " 3 {'_id': 'ga4gh:VA.cbVRtv8fRwNmawjFTS_xfkY_86R6... \n", - " 4 {'_id': 'ga4gh:VA.agiTOwORhUDY1hceBKxCDfUXNQf7... \n", - " ... ... \n", - " 13699 {'_id': 'ga4gh:VA.r615zEzv-YqbeRnBIqwjaelNxr9E... \n", - " 13700 {'_id': 'ga4gh:VA.7E6OACVfPVYnVOGtievDr9a2oP0l... \n", - " 13701 {'_id': 'ga4gh:VA.zvBHULymbpXFCT337LeKFq8822jQ... \n", - " 13702 {'_id': 'ga4gh:VA.evG3TyIwZpryIgd2c9EmOIRBGlmc... \n", - " 13703 {'_id': 'ga4gh:VA.u3HKyvh5midVI8A1IgGm63cdcusr... \n", - " \n", + " 0 {'id': 'ga4gh:VA.R-Nhx9MAdm0FR8VMAgpm8R7sFbKPt... \n", + " 1 {'id': 'ga4gh:VA.R-Nhx9MAdm0FR8VMAgpm8R7sFbKPt... \n", + " 2 {'id': 'ga4gh:VA.R-Nhx9MAdm0FR8VMAgpm8R7sFbKPt... \n", + " 3 {'id': 'ga4gh:VA.R-Nhx9MAdm0FR8VMAgpm8R7sFbKPt... \n", + " 4 {'id': 'ga4gh:VA.Xw7VNiM2VntdVoMt3Movp9xfOaw2C... \n", + " ... ... \n", + " 1960 {'id': 'ga4gh:VA.YEu-uOPKSPlv3IKP36OLVWpQ1LEEW... \n", + " 1961 {'id': 'ga4gh:VA.spzCfx-Z3OFHxDiNeIUyGf5uqdLOe... \n", + " 1962 {'id': 'ga4gh:VA.spzCfx-Z3OFHxDiNeIUyGf5uqdLOe... \n", + " 1963 {'id': 'ga4gh:VA.3Gg0f6pqZxDW0JA5zd-i8JfbFSP4A... \n", + " 1964 {'id': 'ga4gh:VA.3Gg0f6pqZxDW0JA5zd-i8JfbFSP4A... \n", + " \n", + " [1965 rows x 2 columns],\n", + " pre_mapping \\\n", + " 0 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 2 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 3 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 4 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " ... ... \n", + " 1960 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1961 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1962 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1963 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1964 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.geIkNDd-9WbvUyORdGetgadmWXXk... \n", - " 1 {'_id': 'ga4gh:VA.U4CznAWPCpr33nMHOCYHjvsqV-bf... \n", - " 2 {'_id': 'ga4gh:VA.oW5MjBcA2Xay7COb5Rsd06esot31... \n", - " 3 {'_id': 'ga4gh:VA.cbVRtv8fRwNmawjFTS_xfkY_86R6... \n", - " 4 {'_id': 'ga4gh:VA.agiTOwORhUDY1hceBKxCDfUXNQf7... \n", - " ... ... \n", - " 13699 {'_id': 'ga4gh:VA.r615zEzv-YqbeRnBIqwjaelNxr9E... \n", - " 13700 {'_id': 'ga4gh:VA.7E6OACVfPVYnVOGtievDr9a2oP0l... \n", - " 13701 {'_id': 'ga4gh:VA.zvBHULymbpXFCT337LeKFq8822jQ... \n", - " 13702 {'_id': 'ga4gh:VA.evG3TyIwZpryIgd2c9EmOIRBGlmc... \n", - " 13703 {'_id': 'ga4gh:VA.u3HKyvh5midVI8A1IgGm63cdcusr... \n", - " \n", - " [13704 rows x 2 columns],\n", - " 'urn:mavedb:00000001-a-4': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.ab-lV0YLcg3yLadZ1Nrg-b5kjFVr... \n", - " 1 {'_id': 'ga4gh:VA.ykqf36upN66tqYLBczR_WyD1BoyU... \n", - " 2 {'members': [{'_id': 'ga4gh:VA.m0Pv-muJ9wG60rK... \n", - " 3 {'_id': 'ga4gh:VA.QUpJkQQt8lM6eLu17L5XJeSIwfb3... \n", - " 4 {'_id': 'ga4gh:VA.Um0xJaGwrIl2CYq775EYZFe2-OKq... \n", - " ... ... \n", - " 10429 {'_id': 'ga4gh:VA.XZCsgb406NnezSY1rwj0U0z0Tll_... \n", - " 10430 {'members': [{'_id': 'ga4gh:VA.PeH_elNdQOGkgPV... \n", - " 10431 {'_id': 'ga4gh:VA.NoCtKTo6daztnJjBIT5ITfPEavKq... \n", - " 10432 {'members': [{'_id': 'ga4gh:VA.GUlZ__q33sREwCW... \n", - " 10433 {'members': [{'_id': 'ga4gh:VA.VIYGIpYnTWZ_v9i... \n", - " \n", + " 0 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 2 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 3 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 4 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " ... ... \n", + " 1960 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1961 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1962 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1963 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1964 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " \n", + " [1965 rows x 2 columns]],\n", + " 'urn:mavedb:00000055-0-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.PZ4TzypyhPOi0pa7HyfiX7ugDCBUS... \n", + " 1 {'id': 'ga4gh:VA.mt57gu1pxh-LFSsgofp3ebve-0LJw... \n", + " 2 {'id': 'ga4gh:VA.W1Lqk52hcLTxAwUtOwLh1H0QMiFdn... \n", + " 3 {'id': 'ga4gh:VA.keOX5MLI_rk5_ZG8SipID-0yC0ewo... \n", + " 4 {'id': 'ga4gh:VA.IigEnnDHBGdSnWS7hbKCrgJWOVGKe... \n", + " ... ... \n", + " 3009 {'id': 'ga4gh:VA.IPwJdE4ISsXvshE_eC4kxhR4qPhmw... \n", + " 3010 {'id': 'ga4gh:VA.Zu7XUF9AYAXrOYbvl_KzGwd9IEBNN... \n", + " 3011 {'id': 'ga4gh:VA.1nK-ULzhTlDbl2OH2Ad7t-sesjs6k... \n", + " 3012 {'id': 'ga4gh:VA.WlTgx_jxO8d5HyZa7HlIfHdpPQet1... \n", + " 3013 {'id': 'ga4gh:VA.j253_vhu3LaRqM1QiwTTyd4A9M7ZJ... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.ab-lV0YLcg3yLadZ1Nrg-b5kjFVr... \n", - " 1 {'_id': 'ga4gh:VA.ykqf36upN66tqYLBczR_WyD1BoyU... \n", - " 2 {'members': [{'_id': 'ga4gh:VA.m0Pv-muJ9wG60rK... \n", - " 3 {'_id': 'ga4gh:VA.QUpJkQQt8lM6eLu17L5XJeSIwfb3... \n", - " 4 {'_id': 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{'_id': 'ga4gh:VA.1EiRu0ZVxRkvIjzbW3FJUWeRFYs2... \n", - " 3 {'_id': 'ga4gh:VA.ixJQpIpSSgrWSl2ruwUPU86916qZ... \n", - " 4 {'_id': 'ga4gh:VA.PncyY0L8djuKKWlfoNvLYTwfEEe-... \n", - " .. ... \n", - " 741 {'_id': 'ga4gh:VA.-bB23CMgvWL9ub4Tvj75dxsWF5th... \n", - " 742 {'_id': 'ga4gh:VA.G8-k7_LgQu4Y8LKp2-wDSwzwLqVq... \n", - " 743 {'_id': 'ga4gh:VA.OORXvG0LAs5Q1VVfhBQwgQsJqUm7... \n", - " 744 {'_id': 'ga4gh:VA.9svBjChjlnl2uBT9RqiW61OFcj8p... \n", - " 745 {'_id': 'ga4gh:VA.kttLNMSzg0f91lIba3n38hyKH71X... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.WOetJw9pc0iKVkWcGrqSKVCtW98J... \n", - " 1 {'_id': 'ga4gh:VA.BW251ZAhxvDymwdczd2LudMO1NS4... \n", - " 2 {'_id': 'ga4gh:VA.1EiRu0ZVxRkvIjzbW3FJUWeRFYs2... \n", - " 3 {'_id': 'ga4gh:VA.ixJQpIpSSgrWSl2ruwUPU86916qZ... \n", - " 4 {'_id': 'ga4gh:VA.PncyY0L8djuKKWlfoNvLYTwfEEe-... \n", - " .. ... \n", - " 741 {'_id': 'ga4gh:VA.-bB23CMgvWL9ub4Tvj75dxsWF5th... \n", - " 742 {'_id': 'ga4gh:VA.G8-k7_LgQu4Y8LKp2-wDSwzwLqVq... \n", - " 743 {'_id': 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" 2 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 3 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 4 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " ... ... \n", + " 32340 {'id': 'ga4gh:VA.7_coFhHyGU8nIqYUkXvQmw2-igbAO... \n", + " 32341 {'id': 'ga4gh:VA.s3q-ayx5AD37Py5gE91z_56LsDsEd... \n", + " 32342 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 32343 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 32344 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " \n", + " [32345 rows x 2 columns]],\n", + " 'urn:mavedb:00000081-a-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.YUECR-1Kvm-T0TEjgwSNUtVsYYoTk... \n", + " 1 {'id': 'ga4gh:VA.1ktRLMIVftvLIwHKU7FNhhMdjfGIv... \n", + " 2 {'id': 'ga4gh:VA.P8gVQTBY2ckgxQPfwn5UNcvn3J0kw... \n", + " 3 {'id': 'ga4gh:VA.3mLx_W3u_w8mdNvywXiqcNZ2HM567... \n", + " 4 {'id': 'ga4gh:VA.vpe3s8VCFC9tFERvinfq6g4Z3R7o6... \n", + " ... ... \n", + " 1054 {'id': 'ga4gh:VA.vRGhjuf93gZwzofNNlnW_kjW_cMf5... 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1 {'id': 'ga4gh:VA.20j8bIE6AT18tohDxP7n1JrHDclFZ... \n", + " 2 {'id': 'ga4gh:VA.e-IoI5e0Pr7KUeK4Wqt_09HeUG3av... \n", + " 3 {'id': 'ga4gh:VA.OkIsXYBC-vwwg0u33LCxxHdqLu11z... \n", + " 4 {'id': 'ga4gh:VA.Or-yHo1u2DBX6hOyiZMxIjm0ktqzP... \n", + " ... ... \n", + " 2795 {'id': 'ga4gh:VA.DUL_83oGRKCggIq9FZAkWcFEwEJFA... \n", + " 2796 {'id': 'ga4gh:VA.Z-SaNiQFyTFOwz1foCeFyTyTI1LBd... \n", + " 2797 {'id': 'ga4gh:VA.gPFRS0fdeaa5994kbqtNHiUuqcD_q... \n", + " 2798 {'id': 'ga4gh:VA.MaaFXv7-H_qHfL5AEU3USAiHIBgh1... \n", + " 2799 {'id': 'ga4gh:VA.JbNRetrGrHwHmVi63nT3WFxlTJZZ6... \n", + " \n", + " [2800 rows x 2 columns]],\n", + " 'urn:mavedb:00000094-a-14': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.kU0p1RINQTelCBABeQP0Mw6ANZJuM... \n", + " 1 {'id': 'ga4gh:VA.ySqpR5A1P4L2EDxn1DVU_6sb7ba9V... \n", + " 2 {'id': 'ga4gh:VA.kEJ6xPA7W9JgWPVTQPmesMJYkHHhl... \n", + " 3 {'id': 'ga4gh:VA.tJo5t3G_jEA5eNsx-61eUihR7gbGO... \n", + " 4 {'id': 'ga4gh:VA.R58q2R9eA6AfgAHGyJyAicKkFrXCv... \n", + " .. ... \n", + " 57 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'ga4gh:VA.iiRe0be_P-UG2pNkC52_TYeJR8jtb... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.ZTjjIujFTepkPiq6NC_FJOCV4Xcx... \n", - " 1 {'_id': 'ga4gh:VA.csfU6BI7w3o4CpDao2L6poXrgU_g... \n", - " 2 {'_id': 'ga4gh:VA.nNeOPpQfvR5U0dDU6tS4q2DyOrc3... \n", - " 3 {'_id': 'ga4gh:VA.3mFXnXRf_GDaskNrWJ1GxzHcsH33... \n", - " 4 {'_id': 'ga4gh:VA.ad0T7P5HFm0pxWlla4dE2ePWppOu... \n", - " ... ... \n", - " 2795 {'_id': 'ga4gh:VA._dKFs7c3ZQDhpHxcFKduBmMJ1swy... \n", - " 2796 {'_id': 'ga4gh:VA._sshvCz4jEPfPC290EUVSNgE8f-M... \n", - " 2797 {'_id': 'ga4gh:VA.7QMWUUbdAJMccZchynsbSwoQkD24... \n", - " 2798 {'_id': 'ga4gh:VA.ndfWyD-urWki1B-C9WSoGHF71tSb... \n", - " 2799 {'_id': 'ga4gh:VA.gckyxFFs9KT7nVjE_1R9OLGF4kgg... \n", - " \n", - " [2800 rows x 2 columns],\n", - " 'urn:mavedb:00000094-a-14': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.QwVfTjVlfY9oD1vuBFbIEZUwv2GT... \n", - " 1 {'_id': 'ga4gh:VA.E4H9AhnJypyvSBwyz70Zg10mnu17... \n", - " 2 {'_id': 'ga4gh:VA.fIp50GVaB7O3DIdD3g_bxdWYATt2... \n", - " 3 {'_id': 'ga4gh:VA.XZXNkqCMNS5E5JCVvErY_zIsxLME... \n", - " 4 {'_id': 'ga4gh:VA.2f7PkJO8VPZCghgnLsmJkmsISUTl... \n", - " .. ... \n", - " 57 {'_id': 'ga4gh:VA.z5wcAoMiIqV4ortnMVFccUdJPIKy... \n", - " 58 {'_id': 'ga4gh:VA.SNm1CFfXgALnUl7D4IMN4ZG1HPoZ... \n", - " 59 {'_id': 'ga4gh:VA.Rz92q7Rw95tg0xcZLSnBrELbXxhK... \n", - " 60 {'_id': 'ga4gh:VA.PhRuhDJUu-DKJGzr5MyLFigtP7PB... \n", - " 61 {'_id': 'ga4gh:VA.pCcN_FnVcAfGVQCf0ShlLblw8rQT... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.QwVfTjVlfY9oD1vuBFbIEZUwv2GT... \n", - " 1 {'_id': 'ga4gh:VA.E4H9AhnJypyvSBwyz70Zg10mnu17... \n", - " 2 {'_id': 'ga4gh:VA.fIp50GVaB7O3DIdD3g_bxdWYATt2... \n", - " 3 {'_id': 'ga4gh:VA.XZXNkqCMNS5E5JCVvErY_zIsxLME... \n", - " 4 {'_id': 'ga4gh:VA.2f7PkJO8VPZCghgnLsmJkmsISUTl... \n", - " .. ... \n", - " 57 {'_id': 'ga4gh:VA.z5wcAoMiIqV4ortnMVFccUdJPIKy... \n", - " 58 {'_id': 'ga4gh:VA.SNm1CFfXgALnUl7D4IMN4ZG1HPoZ... \n", - " 59 {'_id': 'ga4gh:VA.Rz92q7Rw95tg0xcZLSnBrELbXxhK... \n", - " 60 {'_id': 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'ga4gh:VA.IgbBx-eCgFXIP3okdWD8yi8loZ5rn... \n", + " 3 {'id': 'ga4gh:VA.G2IBqoZTlf-YorQ6IaVfElsSZLkdj... \n", + " 4 {'id': 'ga4gh:VA.0iiU1xdNq2StO7E2I8Ax0Ep00X0Ce... \n", + " .. ... \n", + " 111 {'id': 'ga4gh:VA.uE1tv5QFiaspsHs00DX6i8JpJByWB... \n", + " 112 {'id': 'ga4gh:VA.iiRe0be_P-UG2pNkC52_TYeJR8jtb... \n", + " 113 {'id': 'ga4gh:VA.ghQgElVkxgTlGxbXB0Ch2lNrZRGih... \n", + " 114 {'id': 'ga4gh:VA.ipfihSyZn62cqX56zPxBO49q6pUJP... \n", + " 115 {'id': 'ga4gh:VA.iiRe0be_P-UG2pNkC52_TYeJR8jtb... \n", + " \n", + " [116 rows x 2 columns]],\n", + " 'urn:mavedb:00000045-a-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.KFBRkiWi7B4EYboSX4g6H7pSCmrhf... \n", + " 1 {'id': 'ga4gh:VA.osE32S6eNvvTdLic8kLOdqUM3cbhY... \n", + " 2 {'id': 'ga4gh:VA.onLtKBhKViB9q0nesC92cpbsc7gs6... \n", + " 3 {'id': 'ga4gh:VA.919dxnK6yiXieJIFaLzIdptOKzL-8... \n", + " 4 {'id': 'ga4gh:VA.KHtJ6hcq7cB-MkqzBbHMZZNHZaHEf... \n", + " ... ... \n", + " 2795 {'id': 'ga4gh:VA.DUL_83oGRKCggIq9FZAkWcFEwEJFA... \n", + " 2796 {'id': 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\\\n", + " 0 {'id': 'ga4gh:VA.VumEZjVX5NN5Q6_gkvdDD7wpbB5dk... \n", + " 1 {'id': 'ga4gh:VA.4U0M6eP053d89gYKzuW-cnviNv0Pf... \n", + " 2 {'id': 'ga4gh:VA.VumEZjVX5NN5Q6_gkvdDD7wpbB5dk... \n", + " 3 {'id': 'ga4gh:VA.eB3W3aPqf3Vmg-s0LcBElHH1J5FzQ... \n", + " 4 {'id': 'ga4gh:VA.arLD8K8lXDH4J33rOtYxhK9J-mXbE... \n", + " ... ... \n", + " 2798 {'id': 'ga4gh:VA.8KP6dn6vIsxkJRSE4ef3Qp-KbYqVp... \n", + " 2799 {'id': 'ga4gh:VA.Kg3NxAv2Dx2f5iO7sdTh4D5ihMpoD... \n", + " 2800 {'id': 'ga4gh:VA.O9ciKmfn4TFsZb5Nq0gBkd4w3XTGQ... \n", + " 2801 {'id': 'ga4gh:VA.pASAXl21V8QfOPxsfbQ7xw84xSq-Z... \n", + " 2802 {'id': 'ga4gh:VA.PUMvpqO-IYor-D7SZ4Smkaat2b_-s... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.VumEZjVX5NN5Q6_gkvdDD7wpbB5dk... \n", + " 1 {'id': 'ga4gh:VA.4U0M6eP053d89gYKzuW-cnviNv0Pf... \n", + " 2 {'id': 'ga4gh:VA.VumEZjVX5NN5Q6_gkvdDD7wpbB5dk... \n", + " 3 {'id': 'ga4gh:VA.eB3W3aPqf3Vmg-s0LcBElHH1J5FzQ... \n", + " 4 {'id': 'ga4gh:VA.arLD8K8lXDH4J33rOtYxhK9J-mXbE... \n", + " ... ... \n", + " 2798 {'id': 'ga4gh:VA.8KP6dn6vIsxkJRSE4ef3Qp-KbYqVp... \n", + " 2799 {'id': 'ga4gh:VA.Kg3NxAv2Dx2f5iO7sdTh4D5ihMpoD... \n", + " 2800 {'id': 'ga4gh:VA.O9ciKmfn4TFsZb5Nq0gBkd4w3XTGQ... \n", + " 2801 {'id': 'ga4gh:VA.pASAXl21V8QfOPxsfbQ7xw84xSq-Z... \n", + " 2802 {'id': 'ga4gh:VA.PUMvpqO-IYor-D7SZ4Smkaat2b_-s... \n", + " \n", + " [2803 rows x 2 columns]],\n", + " 'urn:mavedb:00000097-h-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA._BhgovuUZUDnq4u5zfrhCcptvlNDo... \n", + " 1 {'id': 'ga4gh:VA._BhgovuUZUDnq4u5zfrhCcptvlNDo... \n", + " 2 {'id': 'ga4gh:VA._BhgovuUZUDnq4u5zfrhCcptvlNDo... \n", + " 3 {'id': 'ga4gh:VA.YR7_b8OkRoPZSjE3WKP5Fy3rpYWZn... \n", + " 4 {'id': 'ga4gh:VA.Zo2QSgrEyUicGPuPOIMO5rrH4lBP0... \n", + " .. ... \n", + " 241 {'id': 'ga4gh:VA.ZDA_Mb4L2xFqNUHb4jmVOPBKs7Hrm... \n", + " 242 {'id': 'ga4gh:VA.dLi8Y1_bfJfT-n6bGYBCSoAW68D2e... \n", + " 243 {'id': 'ga4gh:VA.qXTI_CG2lp1ZrokNE09kIgdCfiBij... \n", + " 244 {'id': 'ga4gh:VA.qXTI_CG2lp1ZrokNE09kIgdCfiBij... \n", + " 245 {'id': 'ga4gh:VA.HnHxRVSMwE4gh8yZnz68yfRApu194... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.fsBZGfP3BAea2Eop_aasiL_7KwTo... \n", - " 1 {'_id': 'ga4gh:VA.i7rtfcLnVhS7Y3Xixni9gnmBX6rJ... \n", - " 2 {'_id': 'ga4gh:VA.jRB8w-gLOv_nscJm14uJDQcEmhLn... \n", - " 3 {'_id': 'ga4gh:VA.CD1YpSt78AII3w-NntTp8_igp-jj... \n", - " 4 {'_id': 'ga4gh:VA.VmzzoJ83RR3rfw8UOODPmrYGJrq-... \n", - " ... ... \n", - " 6378 {'_id': 'ga4gh:VA.1AELuaoOAFPueXxgWckqtATpZVfS... \n", - " 6379 {'_id': 'ga4gh:VA.x8GY2fHsRNmRArcAIgbYlz3Sgy7J... \n", - " 6380 {'_id': 'ga4gh:VA.Mxz9W5pouT2pE-zjW0OqnmT3EMgc... \n", - " 6381 {'_id': 'ga4gh:VA.xSpUjuSbrZqNiYGzFwvUdErd9fmO... \n", - " 6382 {'_id': 'ga4gh:VA.GrvL7h5bN_x2H_D413uOX3gAPsVu... \n", - " \n", - " [6383 rows x 2 columns],\n", - " 'urn:mavedb:00000094-a-11': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.S8ODyhfy2RD0VeY9g8srenEwxQcs... \n", - " 1 {'_id': 'ga4gh:VA.Fzq3FWUp90GcnX2WmLgZoauSyNR7... \n", - " 2 {'_id': 'ga4gh:VA.QEevWPKmAqQCFT4wviUJEz88AAiQ... \n", - " 3 {'_id': 'ga4gh:VA.A_nRcYQMUnIj3I4l4ZDLh_5NwNQR... \n", - " 4 {'_id': 'ga4gh:VA.FG5aXKjblHmf4iU23C886e-0QoDu... \n", - " .. ... \n", - " 71 {'_id': 'ga4gh:VA.FzfTSqps6hckiUVp99grkwJQhk6o... \n", - " 72 {'_id': 'ga4gh:VA.ue-n7cyn_X9hwYUbTimEw_JebbCr... \n", - " 73 {'_id': 'ga4gh:VA.f58__q9jmzbgf2S1PeOlQkDqwCTd... \n", - " 74 {'_id': 'ga4gh:VA.r-Yx7pZ9NRKKciPuB2gSIEVEf_F2... \n", - " 75 {'_id': 'ga4gh:VA.8dJipbN9pZoz22wvvfI-ySW4HfOf... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.S8ODyhfy2RD0VeY9g8srenEwxQcs... \n", - " 1 {'_id': 'ga4gh:VA.Fzq3FWUp90GcnX2WmLgZoauSyNR7... \n", - " 2 {'_id': 'ga4gh:VA.QEevWPKmAqQCFT4wviUJEz88AAiQ... \n", - " 3 {'_id': 'ga4gh:VA.A_nRcYQMUnIj3I4l4ZDLh_5NwNQR... \n", - " 4 {'_id': 'ga4gh:VA.FG5aXKjblHmf4iU23C886e-0QoDu... \n", - " .. ... \n", - " 71 {'_id': 'ga4gh:VA.FzfTSqps6hckiUVp99grkwJQhk6o... \n", - " 72 {'_id': 'ga4gh:VA.ue-n7cyn_X9hwYUbTimEw_JebbCr... \n", - " 73 {'_id': 'ga4gh:VA.f58__q9jmzbgf2S1PeOlQkDqwCTd... \n", - " 74 {'_id': 'ga4gh:VA.r-Yx7pZ9NRKKciPuB2gSIEVEf_F2... \n", - " 75 {'_id': 'ga4gh:VA.8dJipbN9pZoz22wvvfI-ySW4HfOf... \n", - " \n", - " [76 rows x 2 columns],\n", - " 'urn:mavedb:00000069-a-2': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.3ap48D8Q79kJmk-K1E17_T-tTTFf... \n", - " 1 {'_id': 'ga4gh:VA.JTaw3GEyDgJzzD1KILeNRKufauEr... \n", - " 2 {'_id': 'ga4gh:VA.4OhiYS9VmbNh6IPjwZQUwRz7RlRL... \n", - " 3 {'_id': 'ga4gh:VA.WcKr1_RkqD-wojWaSJCtatmCUJc7... \n", - " 4 {'_id': 'ga4gh:VA.I1skAWb9OySISYSUVFbENFztZSGp... \n", - " ... ... \n", - " 2335 {'_id': 'ga4gh:VA.qTRtT2GzvKud3EMR87yzEXFnCFf3... \n", - " 2336 {'_id': 'ga4gh:VA.v8fbMYgC7cPAO7gxonozApsU4Ej4... \n", - " 2337 {'_id': 'ga4gh:VA.Xrs_toel2IzzJ055Y5gPf2FkESEj... \n", - " 2338 {'_id': 'ga4gh:VA.wzGmWh69YjFaS1fFTCZiGDS8LUjU... \n", - " 2339 {'_id': 'ga4gh:VA.r_MFnDeUMTFFzlre8be_Alw4SJw4... \n", - " \n", + " 0 {'id': 'ga4gh:VA._BhgovuUZUDnq4u5zfrhCcptvlNDo... \n", + " 1 {'id': 'ga4gh:VA._BhgovuUZUDnq4u5zfrhCcptvlNDo... \n", + " 2 {'id': 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{'id': 'ga4gh:VA.sNefRfKNtHApd0962cKr5auRZ7qg2... \n", + " 1 {'id': 'ga4gh:VA.4FODx6a8fNgI_iKBR-fh3Cre10I8g... \n", + " 2 {'id': 'ga4gh:VA.B27uwdYY9iO1dhC512TbD-gN91bJI... \n", + " 3 {'id': 'ga4gh:VA.AaTpu-WV2LvPu5FZf-1SI0onO2JD-... \n", + " 4 {'id': 'ga4gh:VA.Xht9UML3qzG3do0h9YWjxk9WttgZM... \n", + " ... ... \n", + " 6958 {'id': 'ga4gh:VA.NXJXci2A23yjT3ANIjgPJQcWFgj5A... \n", + " 6959 {'id': 'ga4gh:VA.TcdrF7yA-5r40c_eu_FeyYj21dli_... \n", + " 6960 {'id': 'ga4gh:VA.4XGunIjQmkiQZBBkT0WXJcUQkCTJJ... \n", + " 6961 {'id': 'ga4gh:VA.6s_xhxJQI_mpLskGEXvAZcKuqXOrT... \n", + " 6962 {'id': 'ga4gh:VA.BeKzyOqRxqFb3dDzmrnmfQL6b21N1... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.6LRoSkSbLmc_g5xjWUjJoz1kvFKH... \n", - " 1 {'_id': 'ga4gh:VA.8vqdFkW0OCxmMPYpNhHUju5NDOB_... \n", - " 2 {'_id': 'ga4gh:VA.1apfbmLxsNtmMJHGWgREHNVNVTHW... \n", - " 3 {'_id': 'ga4gh:VA.LtLETN-TVHUq4e3r1ecz2LxKMAbT... \n", - " 4 {'_id': 'ga4gh:VA.U0PS_L-e54Ut5E8b3WTOJxgmOqie... \n", - " ... ... \n", - " 18443 {'_id': 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'ga4gh:VA.r_MFnDeUMTFFzlre8be_Alw4SJw4... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.qptEBkcJMw8x7xER9RPdqnKDu3EH... \n", - " 1 {'_id': 'ga4gh:VA.EiJ0U6oNBeFKqMnjrYtkNDscDTSP... \n", - " 2 {'_id': 'ga4gh:VA.3RNOuTtZtd0xOzLqezrPxDbZHFSq... \n", - " 3 {'_id': 'ga4gh:VA.tZMZXPJTYYs61ipgPerW_E33Fshr... \n", - " 4 {'_id': 'ga4gh:VA.rSVdTuSrqFyT5FJOfaBOyV29xU1w... \n", - " ... ... \n", - " 2335 {'_id': 'ga4gh:VA.qTRtT2GzvKud3EMR87yzEXFnCFf3... \n", - " 2336 {'_id': 'ga4gh:VA.v8fbMYgC7cPAO7gxonozApsU4Ej4... \n", - " 2337 {'_id': 'ga4gh:VA.Xrs_toel2IzzJ055Y5gPf2FkESEj... \n", - " 2338 {'_id': 'ga4gh:VA.wzGmWh69YjFaS1fFTCZiGDS8LUjU... \n", - " 2339 {'_id': 'ga4gh:VA.r_MFnDeUMTFFzlre8be_Alw4SJw4... \n", - " \n", - " [2340 rows x 2 columns],\n", - " 'urn:mavedb:00000094-a-13': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.-pcjCCXTKLI85aEU_QOXBPbMpM1Z... \n", - " 1 {'_id': 'ga4gh:VA.WM_YPc7aV9wdgwIuLc6SUzAg-El_... \n", - " 2 {'_id': 'ga4gh:VA.A221adAyFECXuDpq5Uy3QQ2IRRmQ... \n", - " 3 {'_id': 'ga4gh:VA.sgAqv8p-qqy3cqBT1g1GqygV5z62... \n", - " 4 {'_id': 'ga4gh:VA.uhP28prWp3_8nXmbjPobsotDPI24... \n", - " 5 {'_id': 'ga4gh:VA.lNSdg_HZ-1Fwi7ZE_mJtvQyZCect... \n", - " 6 {'_id': 'ga4gh:VA.-MZ9RNMuMcP_RI3j1rPbk_ucakbF... \n", - " 7 {'_id': 'ga4gh:VA.rifLh3MMuC8vGbupstuxwF6m32j2... \n", - " 8 {'_id': 'ga4gh:VA.kARP3Mro9vgd16Yd1aU6KBE4xVb1... \n", - " 9 {'_id': 'ga4gh:VA.yDYfqFmBGEuTdZfMJTki_qVv8xPX... \n", - " 10 {'_id': 'ga4gh:VA.fgN-vvLXYF2NWlXYYGcBGZ-apD3E... \n", - " 11 {'_id': 'ga4gh:VA.WbLAZ2YycOL56tLCq_pFQ0tNyZ2f... \n", - " 12 {'_id': 'ga4gh:VA.U6qCyZ9-B__vUAH8jaF8jcjxZCmw... \n", - " 13 {'_id': 'ga4gh:VA.6CgKqFWbPJ1jsyacZVvnxeC1TTF3... \n", - " 14 {'_id': 'ga4gh:VA.8jrySzd9VqFnA0KhDOdCa9zDthro... \n", - " 15 {'_id': 'ga4gh:VA.mBnYh36eogOgi-hjLU2SIncSe0ni... \n", - " 16 {'_id': 'ga4gh:VA.re8FjaXRyycj2L_N1H7AofCWkyAa... \n", - " 17 {'_id': 'ga4gh:VA.CvJgabT4ChbUU9_Xt2C3hGG_3vuk... \n", - " 18 {'_id': 'ga4gh:VA.xJnPm67IJNXmRNfGnfEFbzBSP3XF... \n", - " 19 {'_id': 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+ " 6959 {'id': 'ga4gh:VA.YD0gmSvlg7vfvaSX2PV8iUbgW_xs-... \n", + " 6960 {'id': 'ga4gh:VA.-kURShNmdExZZbceXrBQt1ALAzX-Y... \n", + " 6961 {'id': 'ga4gh:VA.qWUXjybNf9m9TM7HvEEPdm3GYUuHq... \n", + " 6962 {'id': 'ga4gh:VA.GsvcY6tUSJL4Z3wS4nakjCkW13r_8... \n", + " \n", + " [6963 rows x 2 columns]],\n", + " 'urn:mavedb:00000094-a-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.30Y_WeZGfewE7k9GoSNlYUHzxiB6n... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.-pcjCCXTKLI85aEU_QOXBPbMpM1Z... \n", - " 1 {'_id': 'ga4gh:VA.WM_YPc7aV9wdgwIuLc6SUzAg-El_... \n", - " 2 {'_id': 'ga4gh:VA.A221adAyFECXuDpq5Uy3QQ2IRRmQ... \n", - " 3 {'_id': 'ga4gh:VA.sgAqv8p-qqy3cqBT1g1GqygV5z62... \n", - " 4 {'_id': 'ga4gh:VA.uhP28prWp3_8nXmbjPobsotDPI24... \n", - " 5 {'_id': 'ga4gh:VA.lNSdg_HZ-1Fwi7ZE_mJtvQyZCect... \n", - " 6 {'_id': 'ga4gh:VA.-MZ9RNMuMcP_RI3j1rPbk_ucakbF... \n", - " 7 {'_id': 'ga4gh:VA.rifLh3MMuC8vGbupstuxwF6m32j2... \n", - " 8 {'_id': 'ga4gh:VA.kARP3Mro9vgd16Yd1aU6KBE4xVb1... \n", - " 9 {'_id': 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'ga4gh:VA.ZTjjIujFTepkPiq6NC_FJOCV4Xcx... \n", - " 1 {'_id': 'ga4gh:VA.csfU6BI7w3o4CpDao2L6poXrgU_g... \n", - " 2 {'_id': 'ga4gh:VA.nNeOPpQfvR5U0dDU6tS4q2DyOrc3... \n", - " 3 {'_id': 'ga4gh:VA.3mFXnXRf_GDaskNrWJ1GxzHcsH33... \n", - " 4 {'_id': 'ga4gh:VA.ad0T7P5HFm0pxWlla4dE2ePWppOu... \n", - " ... ... \n", - " 2795 {'_id': 'ga4gh:VA._dKFs7c3ZQDhpHxcFKduBmMJ1swy... \n", - " 2796 {'_id': 'ga4gh:VA._sshvCz4jEPfPC290EUVSNgE8f-M... \n", - " 2797 {'_id': 'ga4gh:VA.7QMWUUbdAJMccZchynsbSwoQkD24... \n", - " 2798 {'_id': 'ga4gh:VA.ndfWyD-urWki1B-C9WSoGHF71tSb... \n", - " 2799 {'_id': 'ga4gh:VA.gckyxFFs9KT7nVjE_1R9OLGF4kgg... \n", - " \n", - " [2800 rows x 2 columns],\n", - " 'urn:mavedb:00000051-c-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.PNKthMVMgyxtSA-c2BomXWUXIF__... \n", - " 1 {'_id': 'ga4gh:VA.JOLvOkFYXt8CkBnpIu5uFDhtkQfW... \n", - " 2 {'_id': 'ga4gh:VA.clqMxg9ZLtE7BzL5YIjAyOguu9pd... \n", - " 3 {'_id': 'ga4gh:VA.LnMBK2I2XuGVmVMNZyyv7sFxgRlE... \n", - " 4 {'_id': 'ga4gh:VA.HJY-MaPQeWSSxPwp6ExE9FdCtzFb... \n", - " .. ... \n", - " 295 {'_id': 'ga4gh:VA.fAZslasd0N5e5q6MxwiIIj_-K_AH... \n", - " 296 {'_id': 'ga4gh:VA.MXWpKNUKjSSGv0YzfSpJpEHqPbyJ... \n", - " 297 {'_id': 'ga4gh:VA.Oas0LyNuLHDkWgDjH6lLwl8tps3b... \n", - " 298 {'_id': 'ga4gh:VA.kn1zjCFvbz7xzyX3gUJfEQ4Rzzwf... \n", - " 299 {'_id': 'ga4gh:VA.iMD5XWFh479zv7S8elXG8xZMsUyQ... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.obF3b5leLNTP3wd71KewNnRCN1gF... \n", - " 1 {'_id': 'ga4gh:VA.00Aak0xd-Ko82v5P_79p4lDv0sRk... \n", - " 2 {'_id': 'ga4gh:VA.saJ6k7b7AkoNyIgVcFjIHzEo_F1f... \n", - " 3 {'_id': 'ga4gh:VA.heoruhoRFE2mys_BGkI_mG-yyzWv... \n", - " 4 {'_id': 'ga4gh:VA.xS0P8VIs8phCpyQ-WABI0DI1t8we... \n", - " .. ... \n", - " 295 {'_id': 'ga4gh:VA.HL97Zo7Kh8Nok4T7rq6kMa0rvD9k... \n", - " 296 {'_id': 'ga4gh:VA.tmwgEwOyLn7KUnFfpBXR4ps4GYHe... \n", - " 297 {'_id': 'ga4gh:VA.MjQME5Emo5i7RuJhCqgamZmVa4nr... \n", - " 298 {'_id': 'ga4gh:VA.XJ0JCjQfBxSYMCTTO5kZ5rUZL4sF... \n", - " 299 {'_id': 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{'_id': 'ga4gh:VA.CD1YpSt78AII3w-NntTp8_igp-jj... \n", - " 4 {'_id': 'ga4gh:VA.VmzzoJ83RR3rfw8UOODPmrYGJrq-... \n", - " ... ... \n", - " 6380 {'_id': 'ga4gh:VA.pqHGaW8eygaJnrHaTXQ4sr_s_3Ju... \n", - " 6381 {'_id': 'ga4gh:VA.cuhrhyOQzXAw9Z5mgoHlqU6Ddsvg... \n", - " 6382 {'_id': 'ga4gh:VA.OfRjLkuxdE9Vu9o8oFvtllU8c3Vu... \n", - " 6383 {'_id': 'ga4gh:VA.5fSlHqh_uXGR0K0I4kkk0UrbJeL7... \n", - " 6384 {'_id': 'ga4gh:VA.CPmhIlCK9P6a0gTzLtSA9jg07cpe... \n", - " \n", - " [6385 rows x 2 columns],\n", - " 'urn:mavedb:00000049-a-8': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.r5FUulAPss5Hsv0NDTHivCR_GM_k... \n", - " 1 {'_id': 'ga4gh:VA.5IMn6Ks0HOBEAoDuktLCSewGvE-h... \n", - " 2 {'_id': 'ga4gh:VA.oX6tzaYnWt0nVYq-iXWZxuV_i0w-... \n", - " 3 {'_id': 'ga4gh:VA.K7OINGlz7Sux0RIX7VWgLNES-Wqp... \n", - " 4 {'_id': 'ga4gh:VA.cOBwg6Ur5sDiuu4ECOzxuYzHr3FJ... \n", - " ... ... \n", - " 12136 {'_id': 'ga4gh:VA.eDCHZ5OPww87CYlfnixU_P8UUfSU... \n", - " 12137 {'_id': 'ga4gh:VA.K31TyKib_bzp_ZGkPQSpGvFiKgbS... \n", - " 12138 {'_id': 'ga4gh:VA.SC8vYAjaz_S7uPpxEdEGMNbF8ujI... \n", - " 12139 {'_id': 'ga4gh:VA.6Wmow794cSz-V30oZK8CdylEa9Qv... \n", - " 12140 {'_id': 'ga4gh:VA.rZ6P_AEoGy7sfuRMNcRYeXXVsSfr... \n", - " \n", + " 0 {'id': 'ga4gh:VA.30Y_WeZGfewE7k9GoSNlYUHzxiB6n... ],\n", + " 'urn:mavedb:00000045-g-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.CUHrKxCDBp2FQ2EyO06idRdorlVG_... \n", + " 1 {'id': 'ga4gh:VA.20j8bIE6AT18tohDxP7n1JrHDclFZ... \n", + " 2 {'id': 'ga4gh:VA.e-IoI5e0Pr7KUeK4Wqt_09HeUG3av... \n", + " 3 {'id': 'ga4gh:VA.OkIsXYBC-vwwg0u33LCxxHdqLu11z... \n", + " 4 {'id': 'ga4gh:VA.Or-yHo1u2DBX6hOyiZMxIjm0ktqzP... \n", + " ... ... \n", + " 2795 {'id': 'ga4gh:VA.DUL_83oGRKCggIq9FZAkWcFEwEJFA... \n", + " 2796 {'id': 'ga4gh:VA.Z-SaNiQFyTFOwz1foCeFyTyTI1LBd... \n", + " 2797 {'id': 'ga4gh:VA.gPFRS0fdeaa5994kbqtNHiUuqcD_q... \n", + " 2798 {'id': 'ga4gh:VA.MaaFXv7-H_qHfL5AEU3USAiHIBgh1... \n", + " 2799 {'id': 'ga4gh:VA.JbNRetrGrHwHmVi63nT3WFxlTJZZ6... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.r5FUulAPss5Hsv0NDTHivCR_GM_k... \n", - " 1 {'_id': 'ga4gh:VA.5IMn6Ks0HOBEAoDuktLCSewGvE-h... \n", - " 2 {'_id': 'ga4gh:VA.oX6tzaYnWt0nVYq-iXWZxuV_i0w-... \n", - " 3 {'_id': 'ga4gh:VA.K7OINGlz7Sux0RIX7VWgLNES-Wqp... \n", - " 4 {'_id': 'ga4gh:VA.cOBwg6Ur5sDiuu4ECOzxuYzHr3FJ... \n", - " ... ... \n", - " 12136 {'_id': 'ga4gh:VA.eDCHZ5OPww87CYlfnixU_P8UUfSU... \n", - " 12137 {'_id': 'ga4gh:VA.K31TyKib_bzp_ZGkPQSpGvFiKgbS... \n", - " 12138 {'_id': 'ga4gh:VA.SC8vYAjaz_S7uPpxEdEGMNbF8ujI... \n", - " 12139 {'_id': 'ga4gh:VA.6Wmow794cSz-V30oZK8CdylEa9Qv... \n", - " 12140 {'_id': 'ga4gh:VA.rZ6P_AEoGy7sfuRMNcRYeXXVsSfr... \n", - " \n", - " [12141 rows x 2 columns],\n", - " 'urn:mavedb:00000047-c-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.rlA8rhTHryLxk7yOE1aGUw9erjjR... \n", - " 1 {'_id': 'ga4gh:VA.L58OQ9zPD19h_Ba9Ffu3bx70XYod... \n", - " 2 {'_id': 'ga4gh:VA.v3FcnZodPI7obYzTVzQbSeXbS-B2... \n", - " 3 {'_id': 'ga4gh:VA.Dp_runNTJLcl87Q1GMX1tBI5h-L8... \n", - " 4 {'_id': 'ga4gh:VA.ipgfC_enkcSB_k5LTDxTZcfGDQJO... \n", - " ... ... \n", - " 7014 {'_id': 'ga4gh:VA.zOc5thrfJAfvXyoG1XWKkLwSDgSu... \n", - " 7015 {'_id': 'ga4gh:VA.uUrRj3BR3jA-W4OO3peBOKoe1VlL... \n", - " 7016 {'_id': 'ga4gh:VA.e94ZW9CyhvgLV-CsAw03kBCDbWXN... \n", - " 7017 {'_id': 'ga4gh:VA.SEAnOXQHmn61c7nM7K4lORVTHccT... \n", - " 7018 {'_id': 'ga4gh:VA.mgE9Kf153pm9pKVjxsLI7anKsOEX... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.eOYTf86-ytcNSPDZCWRN7kKw6Lm1... \n", - " 1 {'_id': 'ga4gh:VA.BzO1LC27XPMPU_YpV7f5rowEa87W... \n", - " 2 {'_id': 'ga4gh:VA.nJMgcFKdmAUe1H3Ux95O5NrbvICl... \n", - " 3 {'_id': 'ga4gh:VA.XYv1-1r7jll4aA9hyngPd3C55Q-0... \n", - " 4 {'_id': 'ga4gh:VA.glNDjxwcpMR2vXjtW8oliMqQdf1m... \n", - " ... ... \n", - " 7014 {'_id': 'ga4gh:VA.uboT_K7H3FUl9Xn-NhqML8t4F-h9... \n", - " 7015 {'_id': 'ga4gh:VA.Q_oVjakUq__9IDycmuQfDbfMiX9L... \n", - " 7016 {'_id': 'ga4gh:VA.RGLkJ9CZoUwTQjjJwJaBmZTWqpG7... \n", - " 7017 {'_id': 'ga4gh:VA.lgtUZ0bh4rjcqejgGyBS3JxyE09Z... \n", - " 7018 {'_id': 'ga4gh:VA.DQQRZ4MvTON70HNs1Cc167-_vnkz... \n", - " \n", - " [7019 rows x 2 columns],\n", - " 'urn:mavedb:00000094-a-8': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.lRS24u_9FSVE5kyeZohrGJq8kDDs... \n", - " 1 {'_id': 'ga4gh:VA.j5No02-cuxJEaxeO_ALvfte0eQx2... \n", - " 2 {'_id': 'ga4gh:VA.8Y2DxfNgOseynvJuGd2BxIIp3nVl... \n", - " 3 {'_id': 'ga4gh:VA.U4AVEawW1tMoF-5DPvsCOMPjX8bs... \n", - " 4 {'_id': 'ga4gh:VA.vC_hLzkFso7gb7BKNHzHERJGPMRi... \n", - " 5 {'_id': 'ga4gh:VA.kfyHphFJxVRvuthqMZ64ThJOjQV6... \n", - " 6 {'_id': 'ga4gh:VA.ByHm6rKn3cghJ11-Q5MnnYKkUlnn... \n", - " 7 {'_id': 'ga4gh:VA.cqRtuIq2mJo0UuA4bupowivmEEiy... \n", - " 8 {'_id': 'ga4gh:VA.J8YnSrQXgV_3Samgn7P1v6tofYlz... \n", - " 9 {'_id': 'ga4gh:VA.1bOm58oh5wIBO9A2eJ2zZNogmt3j... \n", - " 10 {'_id': 'ga4gh:VA.aJnymKKs1VhgFJO5vg5_qom6-xcb... \n", - " 11 {'_id': 'ga4gh:VA.8hSLCkm5PNPuMBxyqo9hhUWYqJf0... \n", - " 12 {'_id': 'ga4gh:VA.C7S_RSHJZQIuFWitSfchDWaJUieE... \n", - " 13 {'_id': 'ga4gh:VA.rDcHFYeSjZDXvflse0RuJnWJEswX... \n", - " 14 {'_id': 'ga4gh:VA.X3l2nwILifZWWo_fnLQmcb9UAA1X... \n", - " 15 {'_id': 'ga4gh:VA.WsHZq1VqEASH_F9Hak7caSzr0OaM... \n", - " 16 {'_id': 'ga4gh:VA.cP-qY6YfKqC4nfgbwPS4gj_yYUbr... \n", - " 17 {'_id': 'ga4gh:VA.wa7KC8VHOo1QzMIa2Mu60iCIjHRB... \n", - " 18 {'_id': 'ga4gh:VA.3ExRnwjfMXibxMD4kZ6hUp63ul2W... \n", - " 19 {'_id': 'ga4gh:VA.aYGY6DPpZyelsWdcXhqHs1det0xN... \n", - " 20 {'_id': 'ga4gh:VA.JB0rYuAEMf2fmagTumtNleLJU6bi... \n", - " 21 {'_id': 'ga4gh:VA.ATLGL9lQlGZUXn_Tzh1xQokcT0U1... \n", - " 22 {'_id': 'ga4gh:VA.TQpYA51FWb4jERV5s-cgSyax1Ms8... \n", - " 23 {'_id': 'ga4gh:VA.pPIgjKOsSpI4lyzgD2DYnopQUP4D... \n", - " 24 {'_id': 'ga4gh:VA.2qJVOrE91panUx5CsRz3iuA12-74... \n", - " 25 {'_id': 'ga4gh:VA.1EI4zcnBwgmrfh0iwlEpN6TFqXs5... \n", - " 26 {'_id': 'ga4gh:VA.nRqqqlxsAB3r67VBIgBZEn538Wvl... \n", - " 27 {'_id': 'ga4gh:VA.xO5JNowreUNMoZaSCugj-2aNvlNw... \n", - " 28 {'_id': 'ga4gh:VA.sg7Dg4E-db3PHtkZboC8ReZXcoPL... \n", - " 29 {'_id': 'ga4gh:VA.8FE0NZYfDTAB2UPidM6zKZSS-IMD... \n", - " 30 {'_id': 'ga4gh:VA.bqmQFTDB_uKqeZUpCmb4B-vjGGi6... \n", - " 31 {'_id': 'ga4gh:VA.aeUBy9jIH3TZFgJ3vm1kclwMCLdv... \n", - " 32 {'_id': 'ga4gh:VA.dnnKwcNHZ7Xw0mIWijgcf0gzo8c7... \n", - " 33 {'_id': 'ga4gh:VA.XICWbfp3l3WBX6-acTpPxQrzGrm7... \n", - " 34 {'_id': 'ga4gh:VA.Umj6LbP9WOE6r2r6fGuTCJOLBSp1... \n", - " 35 {'_id': 'ga4gh:VA.HJtFi0HEZtKtFsHOaBxQTVfmdnND... \n", - " 36 {'_id': 'ga4gh:VA.512j4I5xx3a_lj1FvDGcYEZmaY0V... \n", - " 37 {'_id': 'ga4gh:VA.v1BfKndB0bcF11jeiE4GXNZuUPA3... \n", - " 38 {'_id': 'ga4gh:VA.jdsqAKarRFD0QnqA_dPELtPAjLmS... \n", - " 39 {'_id': 'ga4gh:VA.v17twWP2eeq68mjDS7nBW0E5qK6Q... \n", - " 40 {'_id': 'ga4gh:VA.cuh4AmaMGcP0h4n7q3tHY8SbTBR_... \n", - " 41 {'_id': 'ga4gh:VA.BlYEQ63jTMO1u19m1UwcHt8ppxqr... \n", - " 42 {'_id': 'ga4gh:VA.y2jha7G--ydjcJ4YsALHXkng6HSe... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.lRS24u_9FSVE5kyeZohrGJq8kDDs... \n", - " 1 {'_id': 'ga4gh:VA.j5No02-cuxJEaxeO_ALvfte0eQx2... \n", - " 2 {'_id': 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2 {'id': 'ga4gh:VA.ubrul7y4bwXAM9T2gz_b9RkjNHF3y... \n", + " 3 {'id': 'ga4gh:VA.lZRgu5rEAjK0Z0Hw-b6rEcVa2WmYO... \n", + " 4 {'id': 'ga4gh:VA.oB2AqNt0bWPKX32FeHeOFr53PYkvh... \n", + " ... ... \n", + " 6805 {'id': 'ga4gh:VA.ZKDTxwT7yoinH4CdiaQ2YdFlKCEN6... \n", + " 6806 {'id': 'ga4gh:VA.c5vyOF5dahm-doUvSum5FKJBc-L5K... \n", + " 6807 {'id': 'ga4gh:VA.lZ4TlwoBDnHgv1VGkGbDsR4XR7LI0... \n", + " 6808 {'id': 'ga4gh:VA.eE4ibsuOi818C0H1-JpOzIJPNu1vL... \n", + " 6809 {'id': 'ga4gh:VA.H_7xCjw--slTAAKFwP42WCUo1tITw... \n", + " \n", + " [6810 rows x 2 columns]],\n", + " 'urn:mavedb:00000097-g-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.ciZjtDpTKBX7M4i9dJHbK6Sid4csD... \n", + " 1 {'id': 'ga4gh:VA.XM4IWZO3pzpW-vJLLfsQapkAbEw0u... \n", + " 2 {'id': 'ga4gh:VA.dBCrNuJnFVLKR5lUm48zIE1axRaeK... \n", + " 3 {'id': 'ga4gh:VA.dBCrNuJnFVLKR5lUm48zIE1axRaeK... \n", + " 4 {'id': 'ga4gh:VA.B6Chj29sWZNWFNkRBRrGEa4sHDBZW... \n", + " .. ... \n", + " 241 {'id': 'ga4gh:VA.ZDA_Mb4L2xFqNUHb4jmVOPBKs7Hrm... \n", + " 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" 3 {'id': 'ga4gh:VA.26EV63UcQ6MbTphq4Y2jtLl6uZPgZ... \n", + " 4 {'id': 'ga4gh:VA.jNACKAa57eitLBJPwGQqx7bTzR2Xc... \n", + " .. ... \n", + " 230 {'id': 'ga4gh:VA.Li7q-tO6SO1wIgVKF1nLGEzvZ83ii... \n", + " 231 {'id': 'ga4gh:VA.cnief_bG658fyh6f6ku-EaF5FLFr7... \n", + " 232 {'id': 'ga4gh:VA.Zq8gZeT85_xmymLUx9t8LaaePrKAQ... \n", + " 233 {'id': 'ga4gh:VA.lOjh2t3G19_UhbKq6n9nM0tA4RPOm... \n", + " 234 {'id': 'ga4gh:VA.i1TYI_BCejNMBP1huc0SXquAki9eO... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.mJOTDZMb2b-dFHwq9wAsHGEui2q-... \n", - " 1 {'_id': 'ga4gh:VA.We_nAODDEuAMvSfe28nNlTVo4Q7h... \n", - " 2 {'_id': 'ga4gh:VA.25UnCVSimkNQ6oXHUISTKlW0YTZL... \n", - " 3 {'_id': 'ga4gh:VA.wCPePx-v5vvsCWz2w7Yy50evZrXo... \n", - " 4 {'_id': 'ga4gh:VA.uI2btmkpdkoPJeBTFcDFyYBAkZ4U... \n", - " ... ... \n", - " 5003 {'_id': 'ga4gh:VA.YuYT0Vplfna5gxHDru1S8qmlr_BP... \n", - " 5004 {'_id': 'ga4gh:VA.yi_bPNO46EKNzTyulNmP_I8Squa_... \n", - " 5005 {'_id': 'ga4gh:VA.FloVrKkI-mfVHhXtKFCG32C4SDO_... \n", - " 5006 {'_id': 'ga4gh:VA.ZrirZueaUI0sEwNaAihZJLbWxRcg... \n", - " 5007 {'_id': 'ga4gh:VA.JrY0T8qiCnE1nkTKTxbUd-lqtUuE... \n", - " \n", - " [5008 rows x 2 columns],\n", - " 'urn:mavedb:00000094-a-9': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.lRS24u_9FSVE5kyeZohrGJq8kDDs... \n", - " 1 {'_id': 'ga4gh:VA.j5No02-cuxJEaxeO_ALvfte0eQx2... \n", - " 2 {'_id': 'ga4gh:VA.8Y2DxfNgOseynvJuGd2BxIIp3nVl... \n", - " 3 {'_id': 'ga4gh:VA.U4AVEawW1tMoF-5DPvsCOMPjX8bs... \n", - " 4 {'_id': 'ga4gh:VA.vC_hLzkFso7gb7BKNHzHERJGPMRi... \n", - " 5 {'_id': 'ga4gh:VA.kfyHphFJxVRvuthqMZ64ThJOjQV6... \n", - " 6 {'_id': 'ga4gh:VA.ByHm6rKn3cghJ11-Q5MnnYKkUlnn... \n", - " 7 {'_id': 'ga4gh:VA.cqRtuIq2mJo0UuA4bupowivmEEiy... \n", - " 8 {'_id': 'ga4gh:VA.J8YnSrQXgV_3Samgn7P1v6tofYlz... \n", - " 9 {'_id': 'ga4gh:VA.1bOm58oh5wIBO9A2eJ2zZNogmt3j... \n", - " 10 {'_id': 'ga4gh:VA.aJnymKKs1VhgFJO5vg5_qom6-xcb... \n", - " 11 {'_id': 'ga4gh:VA.8hSLCkm5PNPuMBxyqo9hhUWYqJf0... \n", - " 12 {'_id': 'ga4gh:VA.C7S_RSHJZQIuFWitSfchDWaJUieE... \n", - " 13 {'_id': 'ga4gh:VA.rDcHFYeSjZDXvflse0RuJnWJEswX... \n", - " 14 {'_id': 'ga4gh:VA.X3l2nwILifZWWo_fnLQmcb9UAA1X... \n", - " 15 {'_id': 'ga4gh:VA.WsHZq1VqEASH_F9Hak7caSzr0OaM... \n", - " 16 {'_id': 'ga4gh:VA.cP-qY6YfKqC4nfgbwPS4gj_yYUbr... \n", - " 17 {'_id': 'ga4gh:VA.wa7KC8VHOo1QzMIa2Mu60iCIjHRB... \n", - " 18 {'_id': 'ga4gh:VA.3ExRnwjfMXibxMD4kZ6hUp63ul2W... \n", - " 19 {'_id': 'ga4gh:VA.aYGY6DPpZyelsWdcXhqHs1det0xN... \n", - " 20 {'_id': 'ga4gh:VA.JB0rYuAEMf2fmagTumtNleLJU6bi... \n", - " 21 {'_id': 'ga4gh:VA.ATLGL9lQlGZUXn_Tzh1xQokcT0U1... \n", - " 22 {'_id': 'ga4gh:VA.TQpYA51FWb4jERV5s-cgSyax1Ms8... \n", - " 23 {'_id': 'ga4gh:VA.pPIgjKOsSpI4lyzgD2DYnopQUP4D... \n", - " 24 {'_id': 'ga4gh:VA.2qJVOrE91panUx5CsRz3iuA12-74... \n", - " 25 {'_id': 'ga4gh:VA.1EI4zcnBwgmrfh0iwlEpN6TFqXs5... \n", - " 26 {'_id': 'ga4gh:VA.nRqqqlxsAB3r67VBIgBZEn538Wvl... \n", - " 27 {'_id': 'ga4gh:VA.xO5JNowreUNMoZaSCugj-2aNvlNw... \n", - " 28 {'_id': 'ga4gh:VA.sg7Dg4E-db3PHtkZboC8ReZXcoPL... \n", - " 29 {'_id': 'ga4gh:VA.8FE0NZYfDTAB2UPidM6zKZSS-IMD... \n", - " 30 {'_id': 'ga4gh:VA.bqmQFTDB_uKqeZUpCmb4B-vjGGi6... \n", - " 31 {'_id': 'ga4gh:VA.aeUBy9jIH3TZFgJ3vm1kclwMCLdv... \n", - " 32 {'_id': 'ga4gh:VA.dnnKwcNHZ7Xw0mIWijgcf0gzo8c7... \n", - " 33 {'_id': 'ga4gh:VA.XICWbfp3l3WBX6-acTpPxQrzGrm7... \n", - " 34 {'_id': 'ga4gh:VA.Umj6LbP9WOE6r2r6fGuTCJOLBSp1... \n", - " 35 {'_id': 'ga4gh:VA.HJtFi0HEZtKtFsHOaBxQTVfmdnND... \n", - " 36 {'_id': 'ga4gh:VA.512j4I5xx3a_lj1FvDGcYEZmaY0V... \n", - " 37 {'_id': 'ga4gh:VA.v1BfKndB0bcF11jeiE4GXNZuUPA3... \n", - " 38 {'_id': 'ga4gh:VA.jdsqAKarRFD0QnqA_dPELtPAjLmS... \n", - " 39 {'_id': 'ga4gh:VA.v17twWP2eeq68mjDS7nBW0E5qK6Q... \n", - " 40 {'_id': 'ga4gh:VA.cuh4AmaMGcP0h4n7q3tHY8SbTBR_... \n", - " 41 {'_id': 'ga4gh:VA.BlYEQ63jTMO1u19m1UwcHt8ppxqr... \n", - " 42 {'_id': 'ga4gh:VA.y2jha7G--ydjcJ4YsALHXkng6HSe... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.lRS24u_9FSVE5kyeZohrGJq8kDDs... \n", - " 1 {'_id': 'ga4gh:VA.j5No02-cuxJEaxeO_ALvfte0eQx2... \n", - " 2 {'_id': 'ga4gh:VA.8Y2DxfNgOseynvJuGd2BxIIp3nVl... \n", - " 3 {'_id': 'ga4gh:VA.U4AVEawW1tMoF-5DPvsCOMPjX8bs... \n", - " 4 {'_id': 'ga4gh:VA.vC_hLzkFso7gb7BKNHzHERJGPMRi... \n", - " 5 {'_id': 'ga4gh:VA.kfyHphFJxVRvuthqMZ64ThJOjQV6... \n", - " 6 {'_id': 'ga4gh:VA.ByHm6rKn3cghJ11-Q5MnnYKkUlnn... \n", - " 7 {'_id': 'ga4gh:VA.cqRtuIq2mJo0UuA4bupowivmEEiy... \n", - " 8 {'_id': 'ga4gh:VA.J8YnSrQXgV_3Samgn7P1v6tofYlz... \n", - " 9 {'_id': 'ga4gh:VA.1bOm58oh5wIBO9A2eJ2zZNogmt3j... \n", - " 10 {'_id': 'ga4gh:VA.aJnymKKs1VhgFJO5vg5_qom6-xcb... \n", - " 11 {'_id': 'ga4gh:VA.8hSLCkm5PNPuMBxyqo9hhUWYqJf0... \n", - " 12 {'_id': 'ga4gh:VA.C7S_RSHJZQIuFWitSfchDWaJUieE... \n", - " 13 {'_id': 'ga4gh:VA.rDcHFYeSjZDXvflse0RuJnWJEswX... \n", - " 14 {'_id': 'ga4gh:VA.X3l2nwILifZWWo_fnLQmcb9UAA1X... \n", - " 15 {'_id': 'ga4gh:VA.WsHZq1VqEASH_F9Hak7caSzr0OaM... \n", - " 16 {'_id': 'ga4gh:VA.cP-qY6YfKqC4nfgbwPS4gj_yYUbr... \n", - " 17 {'_id': 'ga4gh:VA.wa7KC8VHOo1QzMIa2Mu60iCIjHRB... \n", - " 18 {'_id': 'ga4gh:VA.3ExRnwjfMXibxMD4kZ6hUp63ul2W... \n", - " 19 {'_id': 'ga4gh:VA.aYGY6DPpZyelsWdcXhqHs1det0xN... \n", - " 20 {'_id': 'ga4gh:VA.JB0rYuAEMf2fmagTumtNleLJU6bi... \n", - " 21 {'_id': 'ga4gh:VA.ATLGL9lQlGZUXn_Tzh1xQokcT0U1... \n", - " 22 {'_id': 'ga4gh:VA.TQpYA51FWb4jERV5s-cgSyax1Ms8... \n", - " 23 {'_id': 'ga4gh:VA.pPIgjKOsSpI4lyzgD2DYnopQUP4D... \n", - " 24 {'_id': 'ga4gh:VA.2qJVOrE91panUx5CsRz3iuA12-74... \n", - " 25 {'_id': 'ga4gh:VA.1EI4zcnBwgmrfh0iwlEpN6TFqXs5... \n", - " 26 {'_id': 'ga4gh:VA.nRqqqlxsAB3r67VBIgBZEn538Wvl... \n", - " 27 {'_id': 'ga4gh:VA.xO5JNowreUNMoZaSCugj-2aNvlNw... \n", - " 28 {'_id': 'ga4gh:VA.sg7Dg4E-db3PHtkZboC8ReZXcoPL... \n", - " 29 {'_id': 'ga4gh:VA.8FE0NZYfDTAB2UPidM6zKZSS-IMD... \n", - " 30 {'_id': 'ga4gh:VA.bqmQFTDB_uKqeZUpCmb4B-vjGGi6... \n", - " 31 {'_id': 'ga4gh:VA.aeUBy9jIH3TZFgJ3vm1kclwMCLdv... \n", - " 32 {'_id': 'ga4gh:VA.dnnKwcNHZ7Xw0mIWijgcf0gzo8c7... \n", - " 33 {'_id': 'ga4gh:VA.XICWbfp3l3WBX6-acTpPxQrzGrm7... \n", - " 34 {'_id': 'ga4gh:VA.Umj6LbP9WOE6r2r6fGuTCJOLBSp1... \n", - " 35 {'_id': 'ga4gh:VA.HJtFi0HEZtKtFsHOaBxQTVfmdnND... \n", - " 36 {'_id': 'ga4gh:VA.512j4I5xx3a_lj1FvDGcYEZmaY0V... \n", - " 37 {'_id': 'ga4gh:VA.v1BfKndB0bcF11jeiE4GXNZuUPA3... \n", - " 38 {'_id': 'ga4gh:VA.jdsqAKarRFD0QnqA_dPELtPAjLmS... \n", - " 39 {'_id': 'ga4gh:VA.v17twWP2eeq68mjDS7nBW0E5qK6Q... \n", - " 40 {'_id': 'ga4gh:VA.cuh4AmaMGcP0h4n7q3tHY8SbTBR_... \n", - " 41 {'_id': 'ga4gh:VA.BlYEQ63jTMO1u19m1UwcHt8ppxqr... \n", - " 42 {'_id': 'ga4gh:VA.y2jha7G--ydjcJ4YsALHXkng6HSe... ,\n", - " 'urn:mavedb:00000045-e-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.ZTjjIujFTepkPiq6NC_FJOCV4Xcx... \n", - " 1 {'_id': 'ga4gh:VA.csfU6BI7w3o4CpDao2L6poXrgU_g... \n", - " 2 {'_id': 'ga4gh:VA.nNeOPpQfvR5U0dDU6tS4q2DyOrc3... \n", - " 3 {'_id': 'ga4gh:VA.3mFXnXRf_GDaskNrWJ1GxzHcsH33... \n", - " 4 {'_id': 'ga4gh:VA.ad0T7P5HFm0pxWlla4dE2ePWppOu... \n", - " ... ... \n", - " 2795 {'_id': 'ga4gh:VA._dKFs7c3ZQDhpHxcFKduBmMJ1swy... \n", - " 2796 {'_id': 'ga4gh:VA._sshvCz4jEPfPC290EUVSNgE8f-M... \n", - " 2797 {'_id': 'ga4gh:VA.7QMWUUbdAJMccZchynsbSwoQkD24... \n", - " 2798 {'_id': 'ga4gh:VA.ndfWyD-urWki1B-C9WSoGHF71tSb... \n", - " 2799 {'_id': 'ga4gh:VA.gckyxFFs9KT7nVjE_1R9OLGF4kgg... \n", - " \n", + " 0 {'id': 'ga4gh:VA.XMopDz0dwRQdssRdn3y5Zp0Z5ezcP... \n", + " 1 {'id': 'ga4gh:VA.4tHHvR1o4F2JQPLJ3vZuKJY3owAII... \n", + " 2 {'id': 'ga4gh:VA.QngWkBqacReF6mt3Bo8wRffdJPRw3... \n", + " 3 {'id': 'ga4gh:VA.26EV63UcQ6MbTphq4Y2jtLl6uZPgZ... \n", + " 4 {'id': 'ga4gh:VA.jNACKAa57eitLBJPwGQqx7bTzR2Xc... \n", + " .. ... \n", + " 230 {'id': 'ga4gh:VA.Li7q-tO6SO1wIgVKF1nLGEzvZ83ii... \n", + " 231 {'id': 'ga4gh:VA.cnief_bG658fyh6f6ku-EaF5FLFr7... \n", + " 232 {'id': 'ga4gh:VA.Zq8gZeT85_xmymLUx9t8LaaePrKAQ... \n", + " 233 {'id': 'ga4gh:VA.lOjh2t3G19_UhbKq6n9nM0tA4RPOm... \n", + " 234 {'id': 'ga4gh:VA.i1TYI_BCejNMBP1huc0SXquAki9eO... \n", + " \n", + " [235 rows x 2 columns]],\n", + " 'urn:mavedb:00000097-k-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.Pheqioq41wWdIm90E1Vq0SrrM4J2i... \n", + " 1 {'id': 'ga4gh:VA.RIs0uKzGfG6akWoftSBnelCLKhe_l... \n", + " 2 {'id': 'ga4gh:VA.xwktbg7btg5vOCqobSoi84k2ymKtP... \n", + " 3 {'id': 'ga4gh:VA.lhLEcRsw79pZ3edV97CUtc63D77Nt... \n", + " 4 {'id': 'ga4gh:VA.lhLEcRsw79pZ3edV97CUtc63D77Nt... \n", + " .. ... \n", + " 246 {'id': 'ga4gh:VA.A0Ghje53eU_rIgSkNZsxcXfKkeIzM... \n", + " 247 {'id': 'ga4gh:VA.AMgQRT4J1RR08CEWdM2zZHSzglgfy... \n", + " 248 {'id': 'ga4gh:VA.b1xmtsFYZ0YsOR2lxsLiTPw9hoRxt... \n", + " 249 {'id': 'ga4gh:VA._iXcY4-V0dM_Hsa7hT43dIA6GWvCS... \n", + " 250 {'id': 'ga4gh:VA.b1xmtsFYZ0YsOR2lxsLiTPw9hoRxt... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.ZTjjIujFTepkPiq6NC_FJOCV4Xcx... \n", - " 1 {'_id': 'ga4gh:VA.csfU6BI7w3o4CpDao2L6poXrgU_g... \n", - " 2 {'_id': 'ga4gh:VA.nNeOPpQfvR5U0dDU6tS4q2DyOrc3... \n", - " 3 {'_id': 'ga4gh:VA.3mFXnXRf_GDaskNrWJ1GxzHcsH33... \n", - " 4 {'_id': 'ga4gh:VA.ad0T7P5HFm0pxWlla4dE2ePWppOu... \n", - " ... ... \n", - " 2795 {'_id': 'ga4gh:VA._dKFs7c3ZQDhpHxcFKduBmMJ1swy... \n", - " 2796 {'_id': 'ga4gh:VA._sshvCz4jEPfPC290EUVSNgE8f-M... \n", - " 2797 {'_id': 'ga4gh:VA.7QMWUUbdAJMccZchynsbSwoQkD24... \n", - " 2798 {'_id': 'ga4gh:VA.ndfWyD-urWki1B-C9WSoGHF71tSb... \n", - " 2799 {'_id': 'ga4gh:VA.gckyxFFs9KT7nVjE_1R9OLGF4kgg... \n", - " \n", - " [2800 rows x 2 columns],\n", - " 'urn:mavedb:00000094-a-15': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.QwVfTjVlfY9oD1vuBFbIEZUwv2GT... \n", - " 1 {'_id': 'ga4gh:VA.E4H9AhnJypyvSBwyz70Zg10mnu17... \n", - " 2 {'_id': 'ga4gh:VA.fIp50GVaB7O3DIdD3g_bxdWYATt2... \n", - " 3 {'_id': 'ga4gh:VA.XZXNkqCMNS5E5JCVvErY_zIsxLME... \n", - " 4 {'_id': 'ga4gh:VA.2f7PkJO8VPZCghgnLsmJkmsISUTl... \n", - " .. ... \n", - " 57 {'_id': 'ga4gh:VA.z5wcAoMiIqV4ortnMVFccUdJPIKy... \n", - " 58 {'_id': 'ga4gh:VA.SNm1CFfXgALnUl7D4IMN4ZG1HPoZ... \n", - " 59 {'_id': 'ga4gh:VA.Rz92q7Rw95tg0xcZLSnBrELbXxhK... \n", - " 60 {'_id': 'ga4gh:VA.PhRuhDJUu-DKJGzr5MyLFigtP7PB... \n", - " 61 {'_id': 'ga4gh:VA.pCcN_FnVcAfGVQCf0ShlLblw8rQT... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.QwVfTjVlfY9oD1vuBFbIEZUwv2GT... \n", - " 1 {'_id': 'ga4gh:VA.E4H9AhnJypyvSBwyz70Zg10mnu17... \n", - " 2 {'_id': 'ga4gh:VA.fIp50GVaB7O3DIdD3g_bxdWYATt2... \n", - " 3 {'_id': 'ga4gh:VA.XZXNkqCMNS5E5JCVvErY_zIsxLME... \n", - " 4 {'_id': 'ga4gh:VA.2f7PkJO8VPZCghgnLsmJkmsISUTl... \n", - " .. ... \n", - " 57 {'_id': 'ga4gh:VA.z5wcAoMiIqV4ortnMVFccUdJPIKy... \n", - " 58 {'_id': 'ga4gh:VA.SNm1CFfXgALnUl7D4IMN4ZG1HPoZ... \n", - " 59 {'_id': 'ga4gh:VA.Rz92q7Rw95tg0xcZLSnBrELbXxhK... \n", - " 60 {'_id': 'ga4gh:VA.PhRuhDJUu-DKJGzr5MyLFigtP7PB... \n", - " 61 {'_id': 'ga4gh:VA.pCcN_FnVcAfGVQCf0ShlLblw8rQT... \n", - " \n", - " [62 rows x 2 columns],\n", - " 'urn:mavedb:00000094-a-2': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.0djwREL84ZFU2JI13Sz1zReInoj8... \n", - " 1 {'_id': 'ga4gh:VA.NOMG99LRu4BTmTL0QqE0r6ef5Cgu... \n", - " 2 {'_id': 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pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.z6-TKfkJCKngP_YxzF4hECK33-pws... \n", + " 1 {'id': 'ga4gh:VA.ZokITP7BQuO66GepatHTXY4Jgll_d... \n", + " 2 {'id': 'ga4gh:VA.9VjOelPiv-w6v-O_XRJpba3xmRbUP... \n", + " 3 {'id': 'ga4gh:VA.-Kq1WK_8XC7xuIeXo9Sg25t3qTP1l... \n", + " 4 {'id': 'ga4gh:VA.ljgGFsPyQ3ohw3ZWsRo8i0KNFjuUv... \n", + " .. ... \n", + " 222 {'id': 'ga4gh:VA.UUsg8JZr-RTPSwPf05z5PkS_kL-hT... \n", + " 223 {'id': 'ga4gh:VA.EMYx7sLeVBVofb5s52nZjqtN725zd... \n", + " 224 {'id': 'ga4gh:VA.RCcp0OCDEm8JIV1P1QocqZCfuZQQj... \n", + " 225 {'id': 'ga4gh:VA.9yM_7J8d2jDlatnu1rA6CAA7BMmXh... \n", + " 226 {'id': 'ga4gh:VA.RCcp0OCDEm8JIV1P1QocqZCfuZQQj... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.ZTjjIujFTepkPiq6NC_FJOCV4Xcx... \n", - " 1 {'_id': 'ga4gh:VA.csfU6BI7w3o4CpDao2L6poXrgU_g... \n", - " 2 {'_id': 'ga4gh:VA.nNeOPpQfvR5U0dDU6tS4q2DyOrc3... \n", - " 3 {'_id': 'ga4gh:VA.3mFXnXRf_GDaskNrWJ1GxzHcsH33... \n", - " 4 {'_id': 'ga4gh:VA.ad0T7P5HFm0pxWlla4dE2ePWppOu... \n", - " ... ... \n", 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{'_id': 'ga4gh:VA.ZNByPYRrRDt3NwvLT32MfE3DSDLO... \n", - " \n", + " 0 {'id': 'ga4gh:VA.z6-TKfkJCKngP_YxzF4hECK33-pws... \n", + " 1 {'id': 'ga4gh:VA.ZokITP7BQuO66GepatHTXY4Jgll_d... \n", + " 2 {'id': 'ga4gh:VA.9VjOelPiv-w6v-O_XRJpba3xmRbUP... \n", + " 3 {'id': 'ga4gh:VA.-Kq1WK_8XC7xuIeXo9Sg25t3qTP1l... \n", + " 4 {'id': 'ga4gh:VA.ljgGFsPyQ3ohw3ZWsRo8i0KNFjuUv... \n", + " .. ... \n", + " 222 {'id': 'ga4gh:VA.UUsg8JZr-RTPSwPf05z5PkS_kL-hT... \n", + " 223 {'id': 'ga4gh:VA.EMYx7sLeVBVofb5s52nZjqtN725zd... \n", + " 224 {'id': 'ga4gh:VA.RCcp0OCDEm8JIV1P1QocqZCfuZQQj... \n", + " 225 {'id': 'ga4gh:VA.9yM_7J8d2jDlatnu1rA6CAA7BMmXh... \n", + " 226 {'id': 'ga4gh:VA.RCcp0OCDEm8JIV1P1QocqZCfuZQQj... \n", + " \n", + " [227 rows x 2 columns]],\n", + " 'urn:mavedb:00000057-b-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.2LCPPJcDvPBNoXYhRMKbh9HNZAob3... \n", + " 1 {'id': 'ga4gh:VA.O9PKiKvsCXGfHjvmYYrjpcDRAbeIc... \n", + " 2 {'id': 'ga4gh:VA.n1_cOh-xNfg2vK8UDNXxUsjSCe6z4... \n", + " 3 {'id': 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{'_id': 'ga4gh:VA._sshvCz4jEPfPC290EUVSNgE8f-M... \n", - " 2797 {'_id': 'ga4gh:VA.7QMWUUbdAJMccZchynsbSwoQkD24... \n", - " 2798 {'_id': 'ga4gh:VA.ndfWyD-urWki1B-C9WSoGHF71tSb... \n", - " 2799 {'_id': 'ga4gh:VA.gckyxFFs9KT7nVjE_1R9OLGF4kgg... \n", - " \n", + " 0 {'id': 'ga4gh:VA.9f2cgWv-PTCutm5hlDahl2NOCpCgW... \n", + " 1 {'id': 'ga4gh:VA.VIJBS25vLnLKDlQBqBJubuQZG88yw... \n", + " 2 {'id': 'ga4gh:VA.PE9-wbOh_MOm3yXInaPHKegg-cg2E... \n", + " 3 {'id': 'ga4gh:VA.bBb8_K8o3m3UTofeO6bIdpK5Uz3U1... \n", + " 4 {'id': 'ga4gh:VA.WoNc5k5D3EvKNo-2uIYUZMWb5740u... \n", + " .. ... \n", + " 149 {'id': 'ga4gh:VA.BvjuLriXs9BQL8wb8ZTKbjRWt3skq... \n", + " 150 {'id': 'ga4gh:VA.qXtHEiI9ArP_oQUcXTuYmAVXV2qhF... \n", + " 151 {'id': 'ga4gh:VA.qXtHEiI9ArP_oQUcXTuYmAVXV2qhF... \n", + " 152 {'id': 'ga4gh:VA.EzfYysqLY41GTvGAFW24-NMoDF0H3... \n", + " 153 {'id': 'ga4gh:VA.12JPP3kzEoGEHt0R3EoxFE3zSUReD... \n", + " \n", + " [154 rows x 2 columns]],\n", + " 'urn:mavedb:00000045-f-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.CUHrKxCDBp2FQ2EyO06idRdorlVG_... \n", + " 1 {'id': 'ga4gh:VA.20j8bIE6AT18tohDxP7n1JrHDclFZ... \n", + " 2 {'id': 'ga4gh:VA.e-IoI5e0Pr7KUeK4Wqt_09HeUG3av... \n", + " 3 {'id': 'ga4gh:VA.OkIsXYBC-vwwg0u33LCxxHdqLu11z... \n", + " 4 {'id': 'ga4gh:VA.Or-yHo1u2DBX6hOyiZMxIjm0ktqzP... \n", + " ... ... \n", + " 2795 {'id': 'ga4gh:VA.DUL_83oGRKCggIq9FZAkWcFEwEJFA... \n", + " 2796 {'id': 'ga4gh:VA.Z-SaNiQFyTFOwz1foCeFyTyTI1LBd... \n", + " 2797 {'id': 'ga4gh:VA.gPFRS0fdeaa5994kbqtNHiUuqcD_q... \n", + " 2798 {'id': 'ga4gh:VA.MaaFXv7-H_qHfL5AEU3USAiHIBgh1... \n", + " 2799 {'id': 'ga4gh:VA.JbNRetrGrHwHmVi63nT3WFxlTJZZ6... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.CUHrKxCDBp2FQ2EyO06idRdorlVG_... \n", + " 1 {'id': 'ga4gh:VA.20j8bIE6AT18tohDxP7n1JrHDclFZ... \n", + " 2 {'id': 'ga4gh:VA.e-IoI5e0Pr7KUeK4Wqt_09HeUG3av... \n", + " 3 {'id': 'ga4gh:VA.OkIsXYBC-vwwg0u33LCxxHdqLu11z... \n", + " 4 {'id': 'ga4gh:VA.Or-yHo1u2DBX6hOyiZMxIjm0ktqzP... \n", + " ... ... \n", + " 2795 {'id': 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'P01857:p.Gly1Ala', 'type': 'Te... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.ZTjjIujFTepkPiq6NC_FJOCV4Xcx... \n", - " 1 {'_id': 'ga4gh:VA.csfU6BI7w3o4CpDao2L6poXrgU_g... \n", - " 2 {'_id': 'ga4gh:VA.nNeOPpQfvR5U0dDU6tS4q2DyOrc3... \n", - " 3 {'_id': 'ga4gh:VA.3mFXnXRf_GDaskNrWJ1GxzHcsH33... \n", - " 4 {'_id': 'ga4gh:VA.ad0T7P5HFm0pxWlla4dE2ePWppOu... \n", - " ... ... \n", - " 2795 {'_id': 'ga4gh:VA._dKFs7c3ZQDhpHxcFKduBmMJ1swy... \n", - " 2796 {'_id': 'ga4gh:VA._sshvCz4jEPfPC290EUVSNgE8f-M... \n", - " 2797 {'_id': 'ga4gh:VA.7QMWUUbdAJMccZchynsbSwoQkD24... \n", - " 2798 {'_id': 'ga4gh:VA.ndfWyD-urWki1B-C9WSoGHF71tSb... \n", - " 2799 {'_id': 'ga4gh:VA.gckyxFFs9KT7nVjE_1R9OLGF4kgg... \n", - " \n", - " [2800 rows x 2 columns],\n", - " 'urn:mavedb:00000065-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.Q9gtBjnoAYcatc57g1hrEXcRYHwP... \n", - " 1 {'_id': 'ga4gh:VA.LEiSQmTQVpQiBZsazJxsi28KKb-Z... \n", - " 2 {'_id': 'ga4gh:VA.mdoEDJQm3bdUAfxOrnlla1p27WIa... \n", - " 3 {'_id': 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mapped \n", + " 0 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 1 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 2 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 3 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 4 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " ... ... \n", + " 3295 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 3296 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 3297 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 3298 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " 3299 {'type': 'Haplotype', 'members': [{'id': 'ga4g... \n", + " \n", + " [3300 rows x 2 columns]],\n", + " 'urn:mavedb:00000068-a-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.M9T_dH2hC9EaD_8l9m7YOkz5V54H9... \n", + " 1 {'id': 'ga4gh:VA.dk7Lrx0FnDBvfZvfFKuUyFCY8Keyd... \n", + " 2 {'id': 'ga4gh:VA.2fMmxAueAGojA5elUYJ_9fL8A7QEt... \n", + " 3 {'id': 'ga4gh:VA.islJUEY3OX5PTpXqw8s5n4aSoL6oC... \n", + " 4 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... ... \n", + " 46208 {'id': 'ga4gh:VA.7obW6ZvcwbYO_Aab62FHFkxNDwcay... \n", + " 46209 {'id': 'ga4gh:VA._uC5xUvycxIokVAGhR0nwpMoRVdqX... \n", + " 46210 {'id': 'ga4gh:VA.vT3C_XXMM8j6ynkxefEY6ZSjqZwi8... \n", + " 46211 {'id': 'ga4gh:VA.qQnpOxUwRRGI34jmH_tK3VFwPueQ7... \n", + " 46212 {'id': 'ga4gh:VA.xEmVKY2y6G_DFnwQ2ewrc48ogyXVu... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.yGYz6W83hu805K6KO4yijhrCFQf-y... \n", + " 1 {'id': 'ga4gh:VA.wyHCqnvpcZDOxPWupQf-7EaUrable... \n", + " 2 {'id': 'ga4gh:VA.M4PM68RhZsGIxq9_GXsuFhZSHbyci... \n", + " 3 {'id': 'ga4gh:VA.kKApwHWG8hVccbu3buWzGD6OlqktL... \n", + " 4 {'id': 'ga4gh:VA.FpU5oEv56iuEUph8eLqP6WSsJHZVG... \n", + " ... ... \n", + " 46208 {'id': 'ga4gh:VA.NxyJqKK8xzdsaeivtLA_-FfLtldYH... \n", + " 46209 {'id': 'ga4gh:VA.M4F3_pJEuXHeV_wIJXYswriSl0TIC... \n", + " 46210 {'id': 'ga4gh:VA.wzkc_9nWaa00vPR0Nh7iiNyceBGwy... \n", + " 46211 {'id': 'ga4gh:VA.VinqzDh5wV7SawKcX52MElubo046G... \n", + " 46212 {'id': 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" 3 {'id': 'ga4gh:VA.Su1x6cPyWs9C2CimKJxATdDXPQISP... \n", + " 4 {'id': 'ga4gh:VA.SOpdi5QFExOmsUQ_MEXNBnG0bPwKj... \n", + " ... ... \n", + " 13699 {'id': 'ga4gh:VA.F5_5Dh6GwTkXbZ21Z7-7S-QMNBIPl... \n", + " 13700 {'id': 'ga4gh:VA.1BtFIFYr80MlByN-lI3DyrQkB84yD... \n", + " 13701 {'id': 'ga4gh:VA.mhvXRaaiSQR4D2SAyWEMdqcE7Mw0x... \n", + " 13702 {'id': 'ga4gh:VA.jeHGpx-9kmg2V90F0w-b1YQCa8yxT... \n", + " 13703 {'id': 'ga4gh:VA.Nvsc75_pVPMuOXNJEuJfqWAc_TlCt... \n", + " \n", + " [13704 rows x 2 columns]],\n", + " 'urn:mavedb:00000013-b-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.BsWcVYuSTHyevpkS_rAwCl_iVaivP... \n", + " 1 {'id': 'ga4gh:VA.wL3MMo0Qx6S4H6752J_JWqwaWecZu... \n", + " 2 {'id': 'ga4gh:VA.g7RqY895lhd3r8TWT_R6kGZzPSM-I... \n", + " 3 {'id': 'ga4gh:VA.farIOfUuZXiI-xB6U4upKPJLH5crV... \n", + " 4 {'id': 'ga4gh:VA.jWpS-lb154ESvc_STXmhU7FYtWrIu... \n", + " ... ... \n", + " 4022 {'id': 'ga4gh:VA.1meuqQDE2fxD5Yaxyn7zRYEx86Ank... \n", + " 4023 {'id': 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{'_id': 'ga4gh:VA.J36Bl7LOg_DUQyWOnN3ROlHLQxNf... \n", - " 9538 {'_id': 'ga4gh:VA.oSyPutd7eiBBlg4Xa0aPWC7NSe_p... \n", - " 9539 {'_id': 'ga4gh:VA.yr5C8pxVlcpXOYwuXCEQEYf3DbJx... \n", - " 9540 {'_id': 'ga4gh:VA.TBjtvTFox6NZyQ5D_NwWJgKPM_zR... \n", - " 9541 {'_id': 'ga4gh:VA.RMVFG5FtnCzwYgyp70T0fqw-qgTx... \n", - " \n", - " [9542 rows x 2 columns],\n", - " 'urn:mavedb:00000057-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.WbGEZoDc-xkm7Ef1EZnFEFu-htl3... \n", - " 1 {'_id': 'ga4gh:VA.JTHyKSY39VeMrHZnTiqGO0A0GW7k... \n", - " 2 {'_id': 'ga4gh:VA.P8YJuXq2Uz9kOZd3JBh7EMMRcrDg... \n", - " 3 {'_id': 'ga4gh:VA.vMyCYXoKcGbTAFRSzamVLFD8tlFP... \n", - " 4 {'_id': 'ga4gh:VA.vIqcn_upKUVo-yi2uVItCpo6RSSg... \n", - " ... ... \n", - " 3295 {'_id': 'ga4gh:VA.fAJqqW_Apv_2fzfRxrMnEk8cL8Si... \n", - " 3296 {'_id': 'ga4gh:VA.GtCcd5tjO5Wk0P0HPSgNo5aRDF-4... \n", - " 3297 {'_id': 'ga4gh:VA.guIQ6k4Hh4uz9AJfLhbdRUuUlvcc... \n", - " 3298 {'_id': 'ga4gh:VA.-CRqRSOUjzw0kQSs7j_RH2RTPDU_... \n", - " 3299 {'_id': 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3299 {'_id': 'ga4gh:VA.-JY7PRsipUMZ7pbURJ3Lu5ZJZ64C... \n", - " \n", - " [3300 rows x 2 columns],\n", - " 'urn:mavedb:00000055-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.YVUrbRpI9Naddy2BzI7Qh4bqNx-7... \n", - " 1 {'_id': 'ga4gh:VA.hzFrWtBiW-FtoXMYRBpi3zI3bpq6... \n", - " 2 {'_id': 'ga4gh:VA.DdyEZbZl-Ggx9YebFp6NavfH-Xwp... \n", - " 3 {'_id': 'ga4gh:VA.E-_x3_dqKmJSBK3Qjm5MOQ0JpEdG... \n", - " 4 {'_id': 'ga4gh:VA.at35Qbi3bB7lbqFs5tPw5aMZ0JH5... \n", - " ... ... \n", - " 3094 {'_id': 'ga4gh:VA.TcFBwQBDIiQ9SDxMjibcLSK-91pO... \n", - " 3095 {'_id': 'ga4gh:VA.ddlsxW4Ppdpe828sSFcdkB5JAhDy... \n", - " 3096 {'_id': 'ga4gh:VA.JDtSTkE5k81idaUIPG_VT5iETis3... \n", - " 3097 {'_id': 'ga4gh:VA.KLNFAzHEUp7zeIUuE62urG8oLYxc... \n", - " 3098 {'_id': 'ga4gh:VA.yLHwegU0RT5o3-KK57FTf1MUYlJe... \n", - " \n", + " 0 {'id': 'ga4gh:VA.LShlXG2q3BVqsMuVqeFNfl9VL0Bw_... \n", + " 1 {'id': 'ga4gh:VA.DvlxSL3OzyC0Beg5DTpcIJ-xGSPNB... \n", + " 2 {'id': 'ga4gh:VA.NccmMA1nG-gmsiUdVzRT70oLjzRFt... \n", + " 3 {'id': 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'ga4gh:VA.otAQMVk4ucwUdx9o4Rr5lxz2DFbr... \n", - " \n", + " 0 {'id': 'ga4gh:VA.kznoVx4h-WaHRLavc6NelJggTiAAu... \n", + " 1 {'id': 'ga4gh:VA.5GOvFG6LIIq_o0VdcE10wowlWFo1F... \n", + " 2 {'id': 'ga4gh:VA.AuRHRhmFy5gqAaI_6RESjdyyPZQty... \n", + " 3 {'id': 'ga4gh:VA.oVw-3INT49d3Ro9-F7hylI6MOQzEX... \n", + " 4 {'id': 'ga4gh:VA.5xHYgQLGum_x8zX0p75xzCX0ynu0B... \n", + " .. ... \n", + " 150 {'id': 'ga4gh:VA.nRz_DHZOQ5tjaUnNRSH59WMb6cTYe... \n", + " 151 {'id': 'ga4gh:VA.Oin0Wg9nIxFJj0av-Vu37fMtI8LaI... \n", + " 152 {'id': 'ga4gh:VA.kq6x2OsvSCyBL2Sg8gIH83P1nRO6b... \n", + " 153 {'id': 'ga4gh:VA.DuqOPjEoYw18UcPTK2_Q--duxJZ8W... \n", + " 154 {'id': 'ga4gh:VA.BnPmV9yDNJMrBHTtOoS7tQNnlFClR... \n", + " \n", + " [155 rows x 2 columns]],\n", + " 'urn:mavedb:00000106-a-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.VI5swJYUFAJUW677Um0MjsNbz09jz... \n", + " 1 {'id': 'ga4gh:VA.w0vlEYnYA0vDYO8TCl8rLvbH5r1Xo... \n", + " 2 {'id': 'ga4gh:VA.eUXufswE_zKlQOa3__LCQd8Jtq4VB... \n", + " 3 {'id': 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{'_id': 'ga4gh:VA.ZTjjIujFTepkPiq6NC_FJOCV4Xcx... \n", - " 1 {'_id': 'ga4gh:VA.csfU6BI7w3o4CpDao2L6poXrgU_g... \n", - " 2 {'_id': 'ga4gh:VA.nNeOPpQfvR5U0dDU6tS4q2DyOrc3... \n", - " 3 {'_id': 'ga4gh:VA.3mFXnXRf_GDaskNrWJ1GxzHcsH33... \n", - " 4 {'_id': 'ga4gh:VA.ad0T7P5HFm0pxWlla4dE2ePWppOu... \n", - " ... ... \n", - " 2795 {'_id': 'ga4gh:VA._dKFs7c3ZQDhpHxcFKduBmMJ1swy... \n", - " 2796 {'_id': 'ga4gh:VA._sshvCz4jEPfPC290EUVSNgE8f-M... \n", - " 2797 {'_id': 'ga4gh:VA.7QMWUUbdAJMccZchynsbSwoQkD24... \n", - " 2798 {'_id': 'ga4gh:VA.ndfWyD-urWki1B-C9WSoGHF71tSb... \n", - " 2799 {'_id': 'ga4gh:VA.gckyxFFs9KT7nVjE_1R9OLGF4kgg... \n", - " \n", - " [2800 rows x 2 columns],\n", - " 'urn:mavedb:00000048-b-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.dYepDGiMhsMoWpVB929f2zt9uCLK... \n", - " 1 {'_id': 'ga4gh:VA.HXCRfqtjEVF_ruoqLtZUDd4cCLYI... \n", - " 2 {'_id': 'ga4gh:VA.eUmzo6hrB84QTkiKKQi-7jzwY31A... \n", - " 3 {'_id': 'ga4gh:VA.KeMbHMeXAxcEwHBkbH4n43A_b1M3... \n", - " 4 {'_id': 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'urn:mavedb:00000049-a-5': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.geIkNDd-9WbvUyORdGetgadmWXXk... \n", - " 1 {'_id': 'ga4gh:VA.U4CznAWPCpr33nMHOCYHjvsqV-bf... \n", - " 2 {'_id': 'ga4gh:VA.oW5MjBcA2Xay7COb5Rsd06esot31... \n", - " 3 {'_id': 'ga4gh:VA.cbVRtv8fRwNmawjFTS_xfkY_86R6... \n", - " 4 {'_id': 'ga4gh:VA.agiTOwORhUDY1hceBKxCDfUXNQf7... \n", - " ... ... \n", - " 13685 {'_id': 'ga4gh:VA.r615zEzv-YqbeRnBIqwjaelNxr9E... \n", - " 13686 {'_id': 'ga4gh:VA.7E6OACVfPVYnVOGtievDr9a2oP0l... \n", - " 13687 {'_id': 'ga4gh:VA.zvBHULymbpXFCT337LeKFq8822jQ... \n", - " 13688 {'_id': 'ga4gh:VA.evG3TyIwZpryIgd2c9EmOIRBGlmc... \n", - " 13689 {'_id': 'ga4gh:VA.u3HKyvh5midVI8A1IgGm63cdcusr... \n", - " \n", + " 0 {'id': 'ga4gh:VA.Lx7mgBevj4uvWZ_5Ynn0AE0T0XQiM... \n", + " 1 {'id': 'ga4gh:VA.7bknyJKu_B3Bh5-R4SbMeYJI1iWrd... \n", + " 2 {'id': 'ga4gh:VA.9dm0nnyNsmhJbKJGCjCYbKssskxX9... \n", + " 3 {'id': 'ga4gh:VA.H9xUKvTC8IfknQJzHGFPhjO_3yLW_... \n", + " 4 {'id': 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3295 {'id': 'ga4gh:VA.DR9kmovNH5EHTzZQM4Yp5P36sHGP6... \n", + " 3296 {'id': 'ga4gh:VA.TNoRUALY6GjstKpvreBffpFtxwnOg... \n", + " 3297 {'id': 'ga4gh:VA.RonAzDFl-xW_cMl_Aa8sFVXnydH6R... \n", + " 3298 {'id': 'ga4gh:VA.AmsWpo22NjFISeHPh8OXMYOHVq8dw... \n", + " 3299 {'id': 'ga4gh:VA.QSlmxEK5APbOLvQHoYZ0KrGn-QxoZ... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.R_NRMFND8gqdH3L-6IB21x_7JYTYE... \n", + " 1 {'id': 'ga4gh:VA.4z2RccskeJxY6VOkY-8nB9FomWVq5... \n", + " 2 {'id': 'ga4gh:VA.FIbrNjrTMCpK7Qg4GojHbCcR50Gyv... \n", + " 3 {'id': 'ga4gh:VA.CoU-AtmkHLnDttAnZFId4eSkzUOmY... \n", + " 4 {'id': 'ga4gh:VA.bTT7Qn8x22QMQ8kmKsqpXfiXehSMF... \n", + " ... ... \n", + " 3295 {'id': 'ga4gh:VA.o5vg_n4VWdf6spj53RSxRdUDuc0hI... \n", + " 3296 {'id': 'ga4gh:VA.09dISOZ3ypLVx9yKopuAAPLizXHTq... \n", + " 3297 {'id': 'ga4gh:VA.gqmeXYmsxyomu388jMZ-3Cw6ULnqw... \n", + " 3298 {'id': 'ga4gh:VA.CXq0lQk1k1jZ5u5f9lVYFYwdDsmic... \n", + " 3299 {'id': 'ga4gh:VA.2w-Zbf5aE0179MuZ0uNrq6RzET00I... \n", + " \n", + " [3300 rows x 2 columns]],\n", + " 'urn:mavedb:00000097-n-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.0Z1Qc7BbHU8dHbtr-esIwrsGq2cux... \n", + " 1 {'id': 'ga4gh:VA._T6PcTfroE_o1jBTDGSdQ0-98Q6fU... \n", + " 2 {'id': 'ga4gh:VA._T6PcTfroE_o1jBTDGSdQ0-98Q6fU... \n", + " 3 {'id': 'ga4gh:VA.803JCe_SSUQzn9-pONE1P99z1-SFN... \n", + " 4 {'id': 'ga4gh:VA.-Fhxr9XVUikJyb70bcm94XC9rYvXv... \n", + " .. ... \n", + " 222 {'id': 'ga4gh:VA.R1NsYoexIkTJiaRxQ8ly2n9CbaUcO... \n", + " 223 {'id': 'ga4gh:VA.YgYhfS8JtSq_TSxUJSBBIxSlji46O... \n", + " 224 {'id': 'ga4gh:VA.5BEi2IPJ9o1LK3Vz9nNXt1O7G4h6H... \n", + " 225 {'id': 'ga4gh:VA.kI8zHHGsQH5RQf8SvETfUwLbLVs66... \n", + " 226 {'id': 'ga4gh:VA.OfP4-AZtVXzAOgD5hK2zs8NmDdWMb... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.ZTjjIujFTepkPiq6NC_FJOCV4Xcx... \n", - " 1 {'_id': 'ga4gh:VA.csfU6BI7w3o4CpDao2L6poXrgU_g... \n", - " 2 {'_id': 'ga4gh:VA.nNeOPpQfvR5U0dDU6tS4q2DyOrc3... \n", - " 3 {'_id': 'ga4gh:VA.3mFXnXRf_GDaskNrWJ1GxzHcsH33... \n", - " 4 {'_id': 'ga4gh:VA.ad0T7P5HFm0pxWlla4dE2ePWppOu... \n", - " ... ... \n", - " 2795 {'_id': 'ga4gh:VA._dKFs7c3ZQDhpHxcFKduBmMJ1swy... \n", - " 2796 {'_id': 'ga4gh:VA._sshvCz4jEPfPC290EUVSNgE8f-M... \n", - " 2797 {'_id': 'ga4gh:VA.7QMWUUbdAJMccZchynsbSwoQkD24... \n", - " 2798 {'_id': 'ga4gh:VA.ndfWyD-urWki1B-C9WSoGHF71tSb... \n", - " 2799 {'_id': 'ga4gh:VA.gckyxFFs9KT7nVjE_1R9OLGF4kgg... \n", - " \n", - " [2800 rows x 2 columns],\n", - " 'urn:mavedb:00000072-a-1': pre_mapping \\\n", - " 0 {'definition': 'P01857:p.Lys99Ter', 'type': 'T... \n", - " 1 {'definition': 'P01857:p.Gln98Ter', 'type': 'T... \n", - " 2 {'definition': 'P01857:p.Thr97Ter', 'type': 'T... \n", - " 3 {'definition': 'P01857:p.Tyr96Ter', 'type': 'T... \n", - " 4 {'definition': 'P01857:p.Glu90Ter', 'type': 'T... \n", - " .. ... \n", - " 693 {'definition': 'P01857:p.Val8Ala', 'type': 'Te... \n", - " 694 {'definition': 'P01857:p.Pro6Ala', 'type': 'Te... \n", - " 695 {'definition': 'P01857:p.Glu5Ala', 'type': 'Te... \n", - " 696 {'definition': 'P01857:p.Pro3Ala', 'type': 'Te... \n", - " 697 {'definition': 'P01857:p.Gly1Ala', 'type': 'Te... \n", - " \n", - " mapped \n", - " 0 {'definition': 'P01857:p.Lys99Ter', 'type': 'T... \n", - " 1 {'definition': 'P01857:p.Gln98Ter', 'type': 'T... \n", - " 2 {'definition': 'P01857:p.Thr97Ter', 'type': 'T... \n", - " 3 {'definition': 'P01857:p.Tyr96Ter', 'type': 'T... \n", - " 4 {'definition': 'P01857:p.Glu90Ter', 'type': 'T... \n", - " .. ... \n", - " 693 {'definition': 'P01857:p.Val8Ala', 'type': 'Te... \n", - " 694 {'definition': 'P01857:p.Pro6Ala', 'type': 'Te... \n", - " 695 {'definition': 'P01857:p.Glu5Ala', 'type': 'Te... \n", - " 696 {'definition': 'P01857:p.Pro3Ala', 'type': 'Te... \n", - " 697 {'definition': 'P01857:p.Gly1Ala', 'type': 'Te... \n", - " \n", - " [698 rows x 2 columns],\n", - " 'urn:mavedb:00000061-b-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA._8KwsU3sY4BypgOHjsCe5TMi3RMK... \n", - " 1 {'_id': 'ga4gh:VA.vYcda-pX5hAyJA9kdsYV2a6qSCG5... \n", - " 2 {'_id': 'ga4gh:VA.8Q7MJ9teWYApwn3n-ibDM9YUKP6j... \n", - " 3 {'_id': 'ga4gh:VA.L9S0vh6aEt3IJrD6ldxO_y5RIygU... \n", - " 4 {'_id': 'ga4gh:VA.wK4QQrCDGpEjI4K24VQWfzRlxTP7... \n", - " .. ... \n", - " 292 {'_id': 'ga4gh:VA.F98-6GGtwLiRoAKgyXJTxtUxI2dD... \n", - " 293 {'_id': 'ga4gh:VA.UWUlR13PFBrV1A7fIPm6kkTpXkAx... \n", - " 294 {'_id': 'ga4gh:VA.i9F6lDdL6UcGJ3ZAW2xXZ5jWLMMJ... \n", - " 295 {'_id': 'ga4gh:VA.Bdn2XIIIxElA_DZhZmPwPE3rzAOC... \n", - " 296 {'_id': 'ga4gh:VA.RBG4Cae25aE-5PYZCY-Z6tU4SmrU... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.kbwbTQQeuDIS-JlPQ-FikXijh2uC... \n", - " 1 {'_id': 'ga4gh:VA.es-nmUGhn9Gtg8pMw6dArUDjuKAc... \n", - " 2 {'_id': 'ga4gh:VA.RfxPfsu0xrJJmY-lQieuPRMSXAdt... \n", - " 3 {'_id': 'ga4gh:VA.UfdAl4Vf2Oz4s9QZI0dLULFoocrr... \n", - " 4 {'_id': 'ga4gh:VA.iSx0Xz6ZMpzTJZwrm_cXn3gQQu4M... \n", - " .. ... \n", - " 292 {'_id': 'ga4gh:VA.Lmh76q6tFugb2b_YNxSNRTsJzCFk... \n", - " 293 {'_id': 'ga4gh:VA._ocC9Z9RtJwai-AwKZfdN_7WtWnj... \n", - " 294 {'_id': 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'ga4gh:VA._T6PcTfroE_o1jBTDGSdQ0-98Q6fU... \n", + " 2 {'id': 'ga4gh:VA._T6PcTfroE_o1jBTDGSdQ0-98Q6fU... \n", + " 3 {'id': 'ga4gh:VA.803JCe_SSUQzn9-pONE1P99z1-SFN... \n", + " 4 {'id': 'ga4gh:VA.-Fhxr9XVUikJyb70bcm94XC9rYvXv... \n", + " .. ... \n", + " 222 {'id': 'ga4gh:VA.R1NsYoexIkTJiaRxQ8ly2n9CbaUcO... \n", + " 223 {'id': 'ga4gh:VA.YgYhfS8JtSq_TSxUJSBBIxSlji46O... \n", + " 224 {'id': 'ga4gh:VA.5BEi2IPJ9o1LK3Vz9nNXt1O7G4h6H... \n", + " 225 {'id': 'ga4gh:VA.kI8zHHGsQH5RQf8SvETfUwLbLVs66... \n", + " 226 {'id': 'ga4gh:VA.OfP4-AZtVXzAOgD5hK2zs8NmDdWMb... \n", + " \n", + " [227 rows x 2 columns]],\n", + " 'urn:mavedb:00000001-d-2': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.c59caMOtFESfpW1HZt_9XBTcKBNAy... \n", + " 1 {'id': 'ga4gh:VA.eFR-ErE-dVWFq5oZIZnhYCH1rbV0k... \n", + " 2 {'id': 'ga4gh:VA.mYCzfkCeHw4q9Znz2jWNp7hhdXG9c... \n", + " 3 {'id': 'ga4gh:VA.cNEbjb42jcIs2tBh2xyF2nxK0v3lq... \n", + " 4 {'id': 'ga4gh:VA.R8oCmXY0HZzS-4lJv_JavzcWMEyVe... \n", + " ... ... \n", + " 4855 {'id': 'ga4gh:VA.lnU6droMMm4HS5F-NJZPTLmW5bgmr... \n", + " 4856 {'id': 'ga4gh:VA.yUJ-wro6Yh5abXj6QWYSkpG5iFuOv... \n", + " 4857 {'id': 'ga4gh:VA.SP7pQSG7zpFxknDuAPGckBeFcuIJC... \n", + " 4858 {'id': 'ga4gh:VA.f0g14XW-eBSDp3jqiVVzbKxfgrLpm... \n", + " 4859 {'id': 'ga4gh:VA.zYLUwCX9KYkg3ObleogiFWO9jvL8t... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.Pauar6TK4XzVrES--DsSr-blPM_L4... \n", + " 1 {'id': 'ga4gh:VA.QL4lCQWzMXIKgFvj0n7yw7NR7TMW2... \n", + " 2 {'id': 'ga4gh:VA.jG8oWCOURcy7dnQGlR88CqLisDWsx... \n", + " 3 {'id': 'ga4gh:VA.yHB3xXLQeiEsSqsfLzAt9ARnx18Z-... \n", + " 4 {'id': 'ga4gh:VA.Mgv_QWm1cIMNJsuI1bFSe2lgiMNj9... \n", + " ... ... \n", + " 4855 {'id': 'ga4gh:VA.bVX47j2v89v536oMNE9W5FIJ6v_HN... \n", + " 4856 {'id': 'ga4gh:VA.GG2D7Mh3a1OkIHMiOzQ9GHgvAPkA6... \n", + " 4857 {'id': 'ga4gh:VA.2c6OV2BI84VejG0AuVNduK_Zgpdzv... \n", + " 4858 {'id': 'ga4gh:VA.nFZ77qyhkPYM38hlCpseibwEEuTle... \n", + " 4859 {'id': 'ga4gh:VA.t7gg0BtuVFpGHz4lRb1gtZ2I5LOzF... \n", + " \n", + " [4860 rows x 2 columns]],\n", + " 'urn:mavedb:00000005-a-3': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.kO4vcDAHd4Jt0CWauKvb-gqsas1eP... \n", + " 1 {'id': 'ga4gh:VA.Py7uJJTu577JRxsjGNYl_DxxFR6jN... \n", + " 2 {'id': 'ga4gh:VA.9Xxbuma5_bUP83N2orUhE9C2cS6pQ... \n", + " 3 {'id': 'ga4gh:VA.bcoAq2_h5ik06j_Y3Dhy8ti4fNlQP... \n", + " 4 {'id': 'ga4gh:VA.k6bTPJbfeqTgOchYXewREMUqGd9aF... \n", + " ... ... \n", + " 11545 {'id': 'ga4gh:VA.zHGWyfdzuJicD_HV_fJ5vUMV32yu0... \n", + " 11546 {'id': 'ga4gh:VA.pdeSdjxGDyHfww4Za0WOdr77TZNEI... \n", + " 11547 {'id': 'ga4gh:VA.ncC06_r6sbnrk3btzFQAecj4uIhZT... \n", + " 11548 {'id': 'ga4gh:VA.ZPdYCr0wTm6pHtHZolFsUDALi9YzM... \n", + " 11549 {'id': 'ga4gh:VA.bBWWvV1S4V6SNKFV2pYowj_pcnCg1... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.kO4vcDAHd4Jt0CWauKvb-gqsas1eP... \n", + " 1 {'id': 'ga4gh:VA.Py7uJJTu577JRxsjGNYl_DxxFR6jN... \n", + " 2 {'id': 'ga4gh:VA.9Xxbuma5_bUP83N2orUhE9C2cS6pQ... \n", + " 3 {'id': 'ga4gh:VA.bcoAq2_h5ik06j_Y3Dhy8ti4fNlQP... \n", + " 4 {'id': 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229 {'id': 'ga4gh:VA.wEKkc9l1nXK5i56rNhLdmSTwosNPa... \n", + " 230 {'id': 'ga4gh:VA.M-RMRevOyFh26IX2NYnAtmbBgn3sa... \n", + " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.00bPsCfj2T8-edk0eHv0dpxFmBaJ... \n", - " 1 {'_id': 'ga4gh:VA.ZAZHeO_YpzoLDjPCWMtgvz62Pfz7... \n", - " 2 {'_id': 'ga4gh:VA.2pU99PNrnYqczMAsoBStdEnSgOm5... \n", - " 3 {'_id': 'ga4gh:VA.JuT-1wqv-HQCWtwRCkXD9eRX67Rp... \n", - " 4 {'_id': 'ga4gh:VA.4TwjgbTKLXDJQb19MiZ02gvnMLl4... \n", - " ... ... \n", - " 6815 {'_id': 'ga4gh:VA.huSTgOggOBG04xQKMuvM70RRuWuY... \n", - " 6816 {'_id': 'ga4gh:VA.bU91PXPCUzZFS1OywzHDvo8_DZR1... \n", - " 6817 {'_id': 'ga4gh:VA.AcqqC7uJJpfC7hEmb5UxYOwe2ejH... \n", - " 6818 {'_id': 'ga4gh:VA.e7TTfgI2xVZpGoX-RkI6YmEBZI3X... \n", - " 6819 {'_id': 'ga4gh:VA.WhrFXCsvM1VOXWs8r-FNdHC6plYe... \n", - " \n", - " [6820 rows x 2 columns],\n", - " 'urn:mavedb:00000001-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.EzVRc1zTcgcd00IfxpHo41E-QpHv... \n", - " 1 {'_id': 'ga4gh:VA.4Td51fMdIEom9XQn_ADuOTVI2VG0... \n", - " 2 {'_id': 'ga4gh:VA.tZ_RcRtXnrPerbPpZIfCo2svAEJK... \n", - " 3 {'_id': 'ga4gh:VA.vouuKduuLHNRARAB9Zc8lsPY7KLb... \n", - " 4 {'_id': 'ga4gh:VA.sZQ6FWxgGZ25ezhJ4P-WANS6kOss... \n", - " ... ... \n", - " 3175 {'_id': 'ga4gh:VA.QBEs9yDNY85PlDUIMar7OOTAEUyb... \n", - " 3176 {'_id': 'ga4gh:VA.9WJ_8eEm_TKmk7zsZYy8Ca6-v0aB... \n", - " 3177 {'_id': 'ga4gh:VA.27Cj2FXkcNUpzLHLTi3VrYnfEVl-... \n", - " 3178 {'_id': 'ga4gh:VA.42RGbtEROh2GE2vl4ACrX1T-B5I8... \n", - " 3179 {'_id': 'ga4gh:VA.zrmUdqP_RsJbxCrdFXPoudfjfetr... \n", - " \n", + " 0 {'id': 'ga4gh:VA.VI5swJYUFAJUW677Um0MjsNbz09jz... \n", + " 1 {'id': 'ga4gh:VA.w0vlEYnYA0vDYO8TCl8rLvbH5r1Xo... \n", + " 2 {'id': 'ga4gh:VA.jPuGm7LxPoJ80cwz9yGL1GJQ2F-M4... \n", + " 3 {'id': 'ga4gh:VA.h6qp1BRgX4tQf9rMRxRoFeQwurRnJ... \n", + " 4 {'id': 'ga4gh:VA.pA38FT-N-KnJqpKNiX6rrN8Cee2cf... \n", + " .. ... \n", + " 226 {'id': 'ga4gh:VA.yz1RKWZvOKB0q-2br8q64NbamiP_E... \n", + " 227 {'id': 'ga4gh:VA.9K9qDCw7wY62-Ejuo0v49_7R3UjLW... \n", + " 228 {'id': 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1 {'id': 'ga4gh:VA.20j8bIE6AT18tohDxP7n1JrHDclFZ... \n", + " 2 {'id': 'ga4gh:VA.e-IoI5e0Pr7KUeK4Wqt_09HeUG3av... \n", + " 3 {'id': 'ga4gh:VA.OkIsXYBC-vwwg0u33LCxxHdqLu11z... \n", + " 4 {'id': 'ga4gh:VA.Or-yHo1u2DBX6hOyiZMxIjm0ktqzP... \n", + " ... ... \n", + " 2795 {'id': 'ga4gh:VA.DUL_83oGRKCggIq9FZAkWcFEwEJFA... \n", + " 2796 {'id': 'ga4gh:VA.Z-SaNiQFyTFOwz1foCeFyTyTI1LBd... \n", + " 2797 {'id': 'ga4gh:VA.gPFRS0fdeaa5994kbqtNHiUuqcD_q... \n", + " 2798 {'id': 'ga4gh:VA.MaaFXv7-H_qHfL5AEU3USAiHIBgh1... \n", + " 2799 {'id': 'ga4gh:VA.JbNRetrGrHwHmVi63nT3WFxlTJZZ6... \n", + " \n", + " [2800 rows x 2 columns]],\n", + " 'urn:mavedb:00000048-b-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.Nns6lI22wj4zZSrdE3A1vhj6UiWxx... \n", + " 1 {'id': 'ga4gh:VA.Fs2g2YjE5VNCMU5MOl1vII59kjLQ2... \n", + " 2 {'id': 'ga4gh:VA.aohAsT27Ox7gJ2MEZz67t3nR2j5PA... \n", + " 3 {'id': 'ga4gh:VA.OYRnW8KcRkr0oSx6sZhAMX4Lsn2LH... \n", + " 4 {'id': 'ga4gh:VA.tNZ4-wCobJbMDQdMq42S60DZ-6tro... \n", + " ... ... \n", + " 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columns]],\n", + " 'urn:mavedb:00000097-q-1': [ pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.zd9KQ6MXWRDzATOVTb-uLkpVNIwFN... \n", + " 1 {'id': 'ga4gh:VA.zd9KQ6MXWRDzATOVTb-uLkpVNIwFN... \n", + " 2 {'id': 'ga4gh:VA.hsikhTdVkyvZ9zDozS2wxJ58G1Vco... \n", + " 3 {'id': 'ga4gh:VA.FL2irtskWC1THh9AwlfTNQ5Jy_ZPO... \n", + " 4 {'id': 'ga4gh:VA.fHwAv8zQ5Gu8UR3fZ1FfqU8SibzCH... \n", + " .. ... \n", + " 239 {'id': 'ga4gh:VA.QiHrMBldMUcAIo2UjsyV8gwlg8N2A... \n", + " 240 {'id': 'ga4gh:VA.oWRw0JvIjvGmZrnX5cerKJkIPQxE5... \n", + " 241 {'id': 'ga4gh:VA.dzaF2m75JDidorD4XuZp-QGguVeG1... \n", + " 242 {'id': 'ga4gh:VA.SkmoVc4jlE17f95625J_SC9iwW9eT... \n", + " 243 {'id': 'ga4gh:VA.1bIrr3oRIl_aFpRr5yh85TSgm7UCA... \n", + " \n", + " mapped \n", + " 0 {'id': 'ga4gh:VA.zd9KQ6MXWRDzATOVTb-uLkpVNIwFN... \n", + " 1 {'id': 'ga4gh:VA.zd9KQ6MXWRDzATOVTb-uLkpVNIwFN... \n", + " 2 {'id': 'ga4gh:VA.hsikhTdVkyvZ9zDozS2wxJ58G1Vco... \n", + " 3 {'id': 'ga4gh:VA.FL2irtskWC1THh9AwlfTNQ5Jy_ZPO... \n", + " 4 {'id': 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coding':\n", " if dat.at[i, 'urn'] in mappings_dict.keys():\n", + " print(dat.at[i, 'urn'])\n", " item = mappings_dict[dat.at[i, 'urn']]\n", " #if blat_check(i) == False:\n", " # vrs_mappings_dict[dat.at[i, 'urn']] = 'BLAT hit not found on correct chromosome'\n", " # continue\n", - " string = 'https://www.mavedb.org/scoreset/' + item[2] + '/scores/'\n", + " string = 'https://www.mavedb.org/scoreset/' + dat.at[i, 'urn'] + '/scores/'\n", " vardat = requests.get(string).content\n", " vardat = pd.read_csv(io.StringIO(vardat.decode('utf-8')), skiprows = 3, header = [1])\n", - " np = item[0]\n", - " \n", - " offset = item[1]\n", - " varm = vardat['hgvs_pro']\n", - "\n", + " scores = vardat['score'].to_list()\n", + " mappings_list = []\n", + " scores_list = []\n", + " \n", + " # Process protein column\n", " var_ids_pre_map = []\n", " var_ids_post_map = []\n", + " \n", + " if len(item) != 0:\n", + " np = item[0]\n", + " offset = item[1]\n", + " varm = vardat['hgvs_pro']\n", " \n", " ts = dat.at[i, 'target_sequence']\n", " if len(set(str(ts))) > 4:\n", " stri = str(ts)\n", + " \n", " else:\n", " ts = Seq(ts)\n", " ts = str(ts.translate(table=1)).replace('*', '')\n", - "\n", + " \n", + " digest = 'SQ.' + sha512t24u(ts.encode('ascii'))\n", + " alias_dict_list = [{'namespace': 'ga4gh', 'alias': digest}]\n", + " sr.store(ts, nsaliases = alias_dict_list) # Add custom digest to SeqRepo\n", + " \n", + " spro = []\n", + " \n", " for j in range(len(varm)):\n", - " if len(varm[j]) == 3 or varm[j] == '_wt' or varm[j] == '_sy':\n", + " if type(varm[j]) != str or len(varm[j]) == 3 or varm[j] == '_wt' or varm[j] == '_sy':\n", " continue\n", + " if varm[j].startswith('NP') == True:\n", + " var_ids_pre_map.append(tr.translate_from(varm[j], 'hgvs').as_dict())\n", + " var_ids_post_map.append(tr.translate_from(varm[j], 'hgvs').as_dict())\n", + " spro.append(scores[j])\n", " else:\n", " try:\n", " if np.startswith('N') == True:\n", - " var_ids_pre_map.append(get_haplotype_allele(varm[j], np, 0, 'p', tr, dp, ts, 'pre').as_dict())\n", - " var_ids_post_map.append(get_haplotype_allele(varm[j], np, offset, 'p', tr, dp, ts, 'post').as_dict())\n", + " var_ids_pre_map.append(get_haplotype_allele(varm[j], np, 0, 'p', tr, dp, ts, 'pre', '', '', '').as_dict())\n", + " var_ids_post_map.append(get_haplotype_allele(varm[j], np, offset, 'p', tr, dp, ts, 'post', '', '', '').as_dict())\n", + " spro.append(scores[j])\n", " else:\n", - " var_ids_pre_map.append(get_haplotype_allele(varm[j], np, 0, 'p', tr, dp, ts, 'pre'))\n", - " var_ids_post_map.append(get_haplotype_allele(varm[j], np, offset, 'p', tr, dp, ts, 'post'))\n", + " var_ids_pre_map.append(get_haplotype_allele(varm[j], np, 0, 'p', tr, dp, ts, 'pre', '', '', ''))\n", + " var_ids_post_map.append(get_haplotype_allele(varm[j], np, offset, 'p', tr, dp, ts, 'post', ranges, hits, ''))\n", + " spro.append(scores[j])\n", " except:\n", " continue\n", " \n", " tempdat = pd.DataFrame({'pre_mapping': var_ids_pre_map, 'mapped': var_ids_post_map})\n", - " vrs_mappings_dict[dat.at[i, 'urn']] = tempdat\n", + " mappings_list.append(tempdat)\n", + " scores_list.append(spro)\n", + " \n", + " # Process nt column if data present\n", + " if vardat['hgvs_nt'].isnull().values.all() == False and '97' not in dat.at[i, 'urn']:\n", + " var_ids_pre_map = []\n", + " var_ids_post_map = []\n", + " \n", + " item = mave_blat_dict[dat.at[i, 'urn']]\n", + " ranges = get_locs_list(item['hits'])\n", + " hits = get_hits_list(item['hits'])\n", + " ref = get_chr(dp, item['chrom'])\n", + " ts = dat.at[i, 'target_sequence']\n", + " strand = mave_blat_dict[dat.at[i, 'urn']]['strand']\n", + " \n", + " digest = 'SQ.' + sha512t24u(ts.encode('ascii'))\n", + " alias_dict_list = [{'namespace': 'ga4gh', 'alias': digest}]\n", + " sr.store(ts, nsaliases = alias_dict_list) # Add custom digest to SeqRepo\n", + " \n", + " ntlist = vardat['hgvs_nt']\n", + " varm = vardat['hgvs_pro']\n", + " sn = []\n", + " \n", + " for j in range(len(ntlist)):\n", + " if type(ntlist[j]) != str or '=' in ntlist[j] or ntlist[j] == '_wt' or ntlist[j] == '_sy':\n", + " continue\n", + " else:\n", + " try:\n", + " var_ids_pre_map.append(get_haplotype_allele(ntlist[j][2:], ref, 0, 'g', tr, dp, ts,'pre', ranges, hits, strand).as_dict())\n", + " var_ids_post_map.append(get_haplotype_allele(ntlist[j][2:], ref, 0, 'g', tr, dp, ts,'post', ranges, hits, strand).as_dict())\n", + " sn.append(scores[j])\n", + " except:\n", + " continue\n", + " \n", + " tempdat = pd.DataFrame({'pre_mapping': var_ids_pre_map, 'mapped': var_ids_post_map})\n", + " mappings_list.append(tempdat)\n", + " scores_list.append(sn)\n", + " \n", + " vrs_mappings_dict[dat.at[i, 'urn']] = mappings_list\n", + " scores_dict_coding[dat.at[i, 'urn']] = scores_list \n", "vrs_mappings_dict" ] }, { "cell_type": "code", - "execution_count": 16, + "execution_count": 4, "id": "ad893d9b", "metadata": {}, "outputs": [ @@ -8176,1116 +12586,1116 @@ { "data": { "text/plain": [ - "{'urn:mavedb:00000023-a-1': 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" 2 {'id': 'ga4gh:VA.4_ejWeoNPilF8gI0OtO4Bc4CtE2aW... \n", + " 3 {'id': 'ga4gh:VA.68MqM6EljGJd6CmxU6dSqWpbKLtWz... \n", + " 4 {'id': 'ga4gh:VA.j2WnQMXJb_Zr44pjD4f1GBtR81cSK... \n", " .. ... \n", - " 550 {'_id': 'ga4gh:VA.ZqG1NlFeMnh8oesU2dZWKi-vdd2n... \n", - " 551 {'_id': 'ga4gh:VA.y0qTlKTZUdZAAY14G1ByzLwPPg0y... \n", - " 552 {'_id': 'ga4gh:VA.9lhi1NMpyaKfVIankqseKE8xCWC_... \n", - " 553 {'_id': 'ga4gh:VA.CEsQMo7mJqiWzSZWAMqyI59CYp6G... \n", - " 554 {'_id': 'ga4gh:VA.uUN1LYjNVKxVaJJ7xbTe_e8hNnMN... \n", + " 550 {'id': 'ga4gh:VA.-EPvgXFL-_5N3JKONEWpDn6_MWIzB... \n", + " 551 {'id': 'ga4gh:VA.eDAu0VwBV-4-4LFundOvvNyj52U_l... \n", + " 552 {'id': 'ga4gh:VA.xyj2UmReAlsFV-jkq_4TnrML8Z0QK... \n", + " 553 {'id': 'ga4gh:VA.TEKj9Y7Rje7gRWoLmWcBqkeGvzT4z... \n", + " 554 {'id': 'ga4gh:VA.EvGMl9kd5n-udRRlLRSosZCgWBwqw... \n", " \n", " [555 rows x 2 columns],\n", - " 'urn:mavedb:00000083-c-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.mg2F7tJ_gAb1fB3IPGEyy_DTeqfv... \n", - " 1 {'_id': 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'urn:mavedb:00000027-a-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.bXaARRRLC_j8hQsTLFyZbzwVrZgao... \n", + " 1 {'id': 'ga4gh:VA.xBJ8RzZDrxGBv_b9bgcaYkcygH7ZD... \n", + " 2 {'id': 'ga4gh:VA.dg16Vsu-Wo6RJEknlj9p9pDdtI9WQ... \n", + " 3 {'id': 'ga4gh:VA.WVWZOSB5H6suPBrjA6IzZ87ZXodbw... \n", + " 4 {'id': 'ga4gh:VA.1cp2RpmmXUbW87si24A1mAJQnKzX8... \n", " ... ... \n", - " 1450 {'_id': 'ga4gh:VA.vLeaUC_Jq-uawk-oFmPWZ3_KZ-jI... \n", - " 1451 {'_id': 'ga4gh:VA.LEMnWH4TlZvRZGaNipgWVl72MgAf... \n", - " 1452 {'_id': 'ga4gh:VA.3kpjzTO4ZjFLvkhjJFrtTkNftO4s... \n", - " 1453 {'_id': 'ga4gh:VA.cg8GwTgLO17w5Fpp47cuiImvkSSJ... \n", - " 1454 {'_id': 'ga4gh:VA.u92jmP1ViSx5GbtIocDiguWsoLgt... \n", + " 1402 {'id': 'ga4gh:VA.I0icEKadO-yskVDZH2pOOH3bzrawy... \n", + " 1403 {'id': 'ga4gh:VA.-XOCitPxSIu0GetMzwuUKOheja4nF... \n", + " 1404 {'id': 'ga4gh:VA.N6R-vg95pY4WLV2RvCJXkyKYk8J3F... \n", + " 1405 {'id': 'ga4gh:VA.Ycaf_kC42g0sJgp0QPq6POdwWeTJq... \n", + " 1406 {'id': 'ga4gh:VA.RLP042y_3gjTj8KlDYHbcIVm3Gwfl... 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'ga4gh:VA.o8VRNCmh6158XLZX8g1UAVqf8wOYx... \n", + " 1403 {'id': 'ga4gh:VA.R5OLYRU-_k3sAvoCEFCUFVD7qMv0u... \n", + " 1404 {'id': 'ga4gh:VA.3yfYohbtJi3Ume9efmJGJEBN8ae92... \n", + " 1405 {'id': 'ga4gh:VA.dQX5e1W0s4xIB6es7KPyt4XGPyODR... \n", + " 1406 {'id': 'ga4gh:VA.4lrecFv4nB6UmGxizpj4PYlvJtKV2... \n", " \n", - " [1455 rows x 2 columns],\n", - " 'urn:mavedb:00000022-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.0A5o-hDPosR1w1u0MzQUy-b-HKsQ... \n", - " 1 {'_id': 'ga4gh:VA.ZnvfdAzmCd4hx25MMMXMzKjVYptD... \n", - " 2 {'_id': 'ga4gh:VA.Rn2GnzgO_0OOr84u7G1zD7OE4YRu... \n", - " 3 {'_id': 'ga4gh:VA.kcyyNatuZchmRHmD_Iim4JOfXHob... \n", - " 4 {'_id': 'ga4gh:VA.j-qrtbIqx6s8f6xbFzpR0_1vzNSg... \n", + " [1407 rows x 2 columns],\n", + " 'urn:mavedb:00000033-a-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.Pm1XZIs5vkTcE7BZHI38jJAEbrUfG... \n", + " 1 {'id': 'ga4gh:VA.UohCgCJpUOMDrFsJAgniB5lkJR4Ud... \n", + " 2 {'id': 'ga4gh:VA.hEQdecrTOhBHqMvRzddB4nMxtPfhS... \n", + " 3 {'id': 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\n", + " 1735 {'id': 'ga4gh:VA.IRCMY5M8VCk5GX1UFhpTMgHf8pfGH... \n", " \n", - " [1785 rows x 2 columns],\n", - " 'urn:mavedb:00000021-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.q0UYtzrWAMqmxs6CizG9n0RB0DKv... \n", - " 1 {'_id': 'ga4gh:VA.jJRqA94UtZBOH23SZbzc3_L8chmX... \n", - " 2 {'_id': 'ga4gh:VA.h-_fwMzSEy_u_aMesCCWtvF32d8P... \n", - " 3 {'_id': 'ga4gh:VA.iRhxSFGkJtO9ui_f3TrkrL6mSWcB... \n", - " 4 {'_id': 'ga4gh:VA.nVbnqyWREH92V2QTcgrXfC3z1MSn... \n", + " [1736 rows x 2 columns],\n", + " 'urn:mavedb:00000083-c-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.5O-2DYgrrqpFtP8Ay4mFTJ7e3joct... \n", + " 1 {'id': 'ga4gh:VA.2mLX4h0mq1L2wxiv0y04tXZKnvgAF... \n", + " 2 {'id': 'ga4gh:VA.MCeLmGcWocOEtlSER1jkzoPPOxGRx... \n", + " 3 {'id': 'ga4gh:VA.spPlxkUEv0EkvJ0QgbEs4-ouAU2OZ... \n", + " 4 {'id': 'ga4gh:VA.az_akyhGmIZX1XfmI5Qv6Pcxmesp0... \n", + " .. ... \n", + " 550 {'id': 'ga4gh:VA.pBqgZGN3oIGXdEG4c5sO8NTBdVv2W... \n", + " 551 {'id': 'ga4gh:VA.5owqIMPXsh4Uh5uIonXvSww4V4hU8... \n", + " 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" 1794 {'id': 'ga4gh:VA.-G-gs4WGhlEPV1tYlBSPAjpK_ZeXM... \n", + " 1795 {'id': 'ga4gh:VA.StnFK2j0HCsKiubdYUJHxi7uBXf8H... \n", + " 1796 {'id': 'ga4gh:VA.4ZglGZ4NaMteIlPmD_IZ7Dezqh2JZ... \n", " \n", - " [1353 rows x 2 columns],\n", - " 'urn:mavedb:00000031-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.oaZL2s4enmAimwnUsw4dtv_o56wz... \n", - " 1 {'_id': 'ga4gh:VA.HgEMaYqEosTasqzpqN7hoQ5fPXmz... \n", - " 2 {'_id': 'ga4gh:VA.yHWoe6TKnnwpaOY18eL5IeR6y_jR... \n", - " 3 {'_id': 'ga4gh:VA.SCGJbNU8HAPwzpWBE9pBbZk07gSE... \n", - " 4 {'_id': 'ga4gh:VA.-Vh2Mn_DEak_JN52ALF4POhOva_V... \n", - " .. ... \n", - " 772 {'_id': 'ga4gh:VA.doaeIc7AdbB47j-9E4WZblpirSz_... \n", - " 773 {'_id': 'ga4gh:VA.GCD50OLlCWcskQwzI3zpAvqNGyCf... \n", - " 774 {'_id': 'ga4gh:VA.7zZweoaP75Sapdt1b4t7VZeUye9d... \n", - " 775 {'_id': 'ga4gh:VA.tTyoIgCCaqka_gWg92RydqTa5RxA... \n", - " 776 {'_id': 'ga4gh:VA.Q71mx562x0q4rg-9IhprUCpFiOor... \n", + " [1797 rows x 2 columns],\n", + " 'urn:mavedb:00000029-a-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.bh1DwN-gvpXGgwUUuH-FLAFHMHBzI... \n", + " 1 {'id': 'ga4gh:VA.1FoXRPaH3U9bMJUesYzj0tzKAyfJ3... \n", + " 2 {'id': 'ga4gh:VA.61P_7sMzllY8ZeYXWyNY7ptePIb1F... \n", + " 3 {'id': 'ga4gh:VA.IuYGtP0WysojxS4Xu3TQIt8pyh1G2... \n", + " 4 {'id': 'ga4gh:VA._jZgsrmN5n8IdlLAXarKyUysh8rG3... \n", + " ... ... \n", + " 1785 {'id': 'ga4gh:VA.oklrCUzYVIZz2eIWMnjQz9GWtxnkT... \n", + " 1786 {'id': 'ga4gh:VA.kXfqxXPUAXDgdmC1snDQCMTVnF_Md... \n", + " 1787 {'id': 'ga4gh:VA.TP4wlVs2lmnugz_waz_QU4Eo1yMBE... \n", + " 1788 {'id': 'ga4gh:VA.cju8zCIdFdS6wB_TkCuE6GJ_6Rfw7... \n", + " 1789 {'id': 'ga4gh:VA.C-KDFV07B4oJYoJxQFfYY1yFgCCRm... \n", " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.zCqMrST02LgT8dVMNBjkHVZ4yu6b... \n", - " 1 {'_id': 'ga4gh:VA.TylU9va_a2EETkYDmDAkEEpv_LF2... \n", - " 2 {'_id': 'ga4gh:VA.F1G-LRowf7Aw9zxPdFPtgmECON6p... \n", - " 3 {'_id': 'ga4gh:VA.zDoW89Z76F6RaPSW4STp9AnHccwK... \n", - " 4 {'_id': 'ga4gh:VA.EyKbWi2aGcih3jeLqQLSos5TXdpU... \n", - " .. ... \n", - " 772 {'_id': 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'urn:mavedb:00000083-i-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.N-L25auao1yHZ60s-WWspiqGQjNY... \n", - " 1 {'_id': 'ga4gh:VA.rF1iVvxN4pCHYhv-fTXN5_H0YRVL... \n", - " 2 {'_id': 'ga4gh:VA.fD3Wm1RqHNVhO53o2X1Lsdqh3tuI... \n", - " 3 {'_id': 'ga4gh:VA.BNoXVCHUJKw8eCPmdM02rjh-k6TS... \n", - " 4 {'_id': 'ga4gh:VA.SPGJ3P34L7O3JCNG1dQw3LTF2NNR... \n", + " [1790 rows x 2 columns],\n", + " 'urn:mavedb:00000083-g-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.M5mumj7br3HUUUmWzlZ_agW2obj4I... \n", + " 1 {'id': 'ga4gh:VA.12GJoWis85phd_LH1MN-HBVqFQ7ae... \n", + " 2 {'id': 'ga4gh:VA.bvRNlC42_7GxCDF_wTmNF08BCmJEW... \n", + " 3 {'id': 'ga4gh:VA.DvzGGCQnXKZunaEkINnrkAQBSHg8M... \n", + " 4 {'id': 'ga4gh:VA.FknevZoOwRMPBdg1hjmqBbJAD9pWp... \n", " .. ... \n", - " 550 {'_id': 'ga4gh:VA.-Sxc1pwswsE38XsvPM_J42u9NeXw... \n", - " 551 {'_id': 'ga4gh:VA.uhlJsUyH8FH_p3Zm75ZKnIZKJMik... \n", - " 552 {'_id': 'ga4gh:VA.lfYst4e4w01vEKWRrsExbR6hqd-k... \n", - " 553 {'_id': 'ga4gh:VA.jM_m9TdYRCYOFwcasU9wedS8Z039... \n", - " 554 {'_id': 'ga4gh:VA.r4oez3v0dkcwUdaeBdjMUe9MYCW3... \n", + " 550 {'id': 'ga4gh:VA.BfGn-CUt26LXGCHLSQKWl2qogNWGG... \n", + " 551 {'id': 'ga4gh:VA.baT00bPATu23R0fNJlesRyIxqYx0p... \n", + " 552 {'id': 'ga4gh:VA.JcTTFWyghF6l2nwA4MxdnmIBxdRsq... \n", + " 553 {'id': 'ga4gh:VA.JKVokDEEZnkIaRWu4yWRzszN3Y8W8... \n", + " 554 {'id': 'ga4gh:VA.Vexq_ye3Zj-0-lGOlHcs8dxnjmZpX... \n", " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.g1niS-RXuL028eosmvCpNYHUrnTl... \n", - " 1 {'_id': 'ga4gh:VA.h_XKiqvtOD6VerQXCAdYe6PxBJ0E... \n", - " 2 {'_id': 'ga4gh:VA.BAtfYatx6z38DgW1sZ4OOqrpwQ0s... \n", - " 3 {'_id': 'ga4gh:VA.B3BpFB5PUQOHx_2Uk2Qo4_IM0WBj... \n", - " 4 {'_id': 'ga4gh:VA.88V5NoQayFLEpXkszdFJdKWGDR50... \n", + " 0 {'id': 'ga4gh:VA.LPcKxe9xRP1811QlRD3FgNsrmD03I... \n", + " 1 {'id': 'ga4gh:VA.ducGHJNOx8_siUL2Pl3k5-qIglZpq... \n", + " 2 {'id': 'ga4gh:VA.sQaO8RZxWEjWgnQOWOV1VQdEUskxa... \n", + " 3 {'id': 'ga4gh:VA.-YDB8SYFqa7Xiwf3rOgBgLRuo-6v-... \n", + " 4 {'id': 'ga4gh:VA.yy9YV7Qi7OYiZ0kMJDKo-JdVrMaYs... \n", " .. ... \n", - " 550 {'_id': 'ga4gh:VA.ZqG1NlFeMnh8oesU2dZWKi-vdd2n... \n", - " 551 {'_id': 'ga4gh:VA.y0qTlKTZUdZAAY14G1ByzLwPPg0y... \n", - " 552 {'_id': 'ga4gh:VA.9lhi1NMpyaKfVIankqseKE8xCWC_... \n", - " 553 {'_id': 'ga4gh:VA.CEsQMo7mJqiWzSZWAMqyI59CYp6G... \n", - " 554 {'_id': 'ga4gh:VA.uUN1LYjNVKxVaJJ7xbTe_e8hNnMN... \n", + " 550 {'id': 'ga4gh:VA.-EPvgXFL-_5N3JKONEWpDn6_MWIzB... \n", + " 551 {'id': 'ga4gh:VA.eDAu0VwBV-4-4LFundOvvNyj52U_l... \n", + " 552 {'id': 'ga4gh:VA.xyj2UmReAlsFV-jkq_4TnrML8Z0QK... \n", + " 553 {'id': 'ga4gh:VA.TEKj9Y7Rje7gRWoLmWcBqkeGvzT4z... \n", + " 554 {'id': 'ga4gh:VA.EvGMl9kd5n-udRRlLRSosZCgWBwqw... \n", " \n", " [555 rows x 2 columns],\n", - " 'urn:mavedb:00000015-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.yTdZFVN8jptLTYeuIoB_3kSZNY0f... \n", - " 1 {'_id': 'ga4gh:VA.qg4tjHIo87gqHaUGhppXe_5psWo1... \n", - " 2 {'_id': 'ga4gh:VA.QDtMWWsk5UDYIteSqTsIgmFRfYHN... \n", - " 3 {'_id': 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" 2 {'id': 'ga4gh:VA.jb33WUiCQUPvQh-ecmfXq0RnCUrWk... \n", + " 3 {'id': 'ga4gh:VA.17QoPfcw9MsdeHweuccwcygF2FSHW... \n", + " 4 {'id': 'ga4gh:VA.Bw5mZc4-e4GQUaWMbIpkaf82Zy4hO... \n", " .. ... \n", - " 899 {'_id': 'ga4gh:VA.Dy-pCMoMg58WpA3w4dFKtxdVIWqW... \n", - " 900 {'_id': 'ga4gh:VA.ixgTKrpt0sAicP0ACIPYKai7h_kE... \n", - " 901 {'_id': 'ga4gh:VA.mprbv4ogpWBq_7SCLGLvawpFLVgo... \n", - " 902 {'_id': 'ga4gh:VA.y-fb-etsr7rVDknnV0AXVgd--fyE... \n", - " 903 {'_id': 'ga4gh:VA.zE5tQwHFgyIm2FhgbVsmmCOvuwnr... \n", + " 772 {'id': 'ga4gh:VA.yvVjMG5eV01Fb9CgKVJnhP96B6Zpe... \n", + " 773 {'id': 'ga4gh:VA.izFe7HU_t08s43qS2bNweLxfnykg7... \n", + " 774 {'id': 'ga4gh:VA.WrdAJH_vjJVCOLj-CN7e8t4CFUSi6... \n", + " 775 {'id': 'ga4gh:VA.nzM8-87GQAH-kUPUXS9WPdOP5afJ0... \n", + " 776 {'id': 'ga4gh:VA.eGy4aiGzH6DMm8C_KAJRk2jzsCFEi... \n", " \n", - " [904 rows x 2 columns],\n", - " 'urn:mavedb:00000025-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.dAQt7q1nhMk7i7DNNN-eTm14T-Mo... \n", - " 1 {'_id': 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'ga4gh:VA.CLGdLuLygkLE7xLUjpGbPdLh2_3b... \n", + " [777 rows x 2 columns],\n", + " 'urn:mavedb:00000022-a-1': pre_mapping \\\n", + " 0 {'id': 'ga4gh:VA.5tl_2WF9MuoBkza2ehWg_HUZsWkzR... \n", + " 1 {'id': 'ga4gh:VA.CrhmpHhNRRsgH-fRgRXe6xUlZUwgQ... \n", + " 2 {'id': 'ga4gh:VA.ztstZYOUI8dBPOl9t9BSXx94IsdiB... \n", + " 3 {'id': 'ga4gh:VA.nzqR_pxmq3Jx61lzPHh6TxxD3G9D0... \n", + " 4 {'id': 'ga4gh:VA.QDz1dynwE5jUIAC4OO6I6G-EEu4cz... \n", " ... ... \n", - " 1384 {'_id': 'ga4gh:VA._abGlPYq1-VaV7Ajd802U5lwAPDL... \n", - " 1385 {'_id': 'ga4gh:VA.p0-elC0B73E-s3eZSQqUMOxXJkmK... \n", - " 1386 {'_id': 'ga4gh:VA.BIPUuunz9jRSq2ClpikPORxtEdub... \n", - " 1387 {'_id': 'ga4gh:VA.y2CoIy3URL6cQy4bxSDvoAE0Qxqu... \n", - " 1388 {'_id': 'ga4gh:VA.qgWrOcLWW2DVJ3WZTewklzxGC9p7... \n", + " 1780 {'id': 'ga4gh:VA.tB6pftvOrybqiFeizlhC2GdMb1QDO... \n", + " 1781 {'id': 'ga4gh:VA.drmh4FJkTcomgymkNTfoGZqeSSO7i... \n", + " 1782 {'id': 'ga4gh:VA.TlsUXj_bPKRzrzaKiqbuJcaHH6pp4... \n", + " 1783 {'id': 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{'id': 'ga4gh:VA.f9hWUWMv8OhoWKvXY_33tHG8wkbx9... \n", + " 902 {'id': 'ga4gh:VA.IK09qEpTt6xC-jFSSefpyWkscHfzk... \n", + " 903 {'id': 'ga4gh:VA.vaYuHBIaWTrwfU3U5CLgGaS1bGzV8... \n", " \n", - " [555 rows x 2 columns],\n", - " 'urn:mavedb:00000083-e-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.bjnjn4K8ePQ4cbDOkt8gxx16ADo8... \n", - " 1 {'_id': 'ga4gh:VA.8GaILvPG443eLLMqLxbkdTA32qDI... \n", - " 2 {'_id': 'ga4gh:VA.osz0-_Gstbitee0W1m-qauV2SwPf... \n", - " 3 {'_id': 'ga4gh:VA.Zdn_l5KzoWM4698bLBOP-lZBom9v... \n", - " 4 {'_id': 'ga4gh:VA.ErUq6otYY5IRdLWV5FGlK2A3FlI4... \n", - " .. ... \n", - " 550 {'_id': 'ga4gh:VA.wGVQgAe-JHrdkmKfYu69ki2GbDC9... \n", - " 551 {'_id': 'ga4gh:VA.aajYJ8H32bE0ysAlcuj0nX9WoYY-... \n", - " 552 {'_id': 'ga4gh:VA.k_1kmIZIrHR6X1w4cfcFYr1Q0lqh... \n", - " 553 {'_id': 'ga4gh:VA.CqGlJNXODRw716Ys6RIhiby1YQhF... \n", - " 554 {'_id': 'ga4gh:VA.QCwih1r6aTPf1W6kcrNP_0Cuuhhq... \n", + " [904 rows x 2 columns],\n", + " 'urn:mavedb:00000025-a-1': pre_mapping \\\n", + " 0 {'id': 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[1792 rows x 2 columns],\n", " 'urn:mavedb:00000019-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.qbrLszlyB_lXRT6VOtRYRuTbfOCl... \n", - " 1 {'_id': 'ga4gh:VA.0xk1ykUIenk1DTxHboZ3KiKgME2z... \n", - " 2 {'_id': 'ga4gh:VA.6KdPtWfPxxlMfMWT0jlhxKsC6zvZ... \n", - " 3 {'_id': 'ga4gh:VA.byOaz_9nkqeI3sJbmEj29C7PtTOy... \n", - " 4 {'_id': 'ga4gh:VA.Ta6hxy7NU8_X0V9bjc0psU0aHCGL... \n", + " 0 {'id': 'ga4gh:VA.L1sFQeuGXVAMC5jBFs2jBPaB9SQkE... \n", + " 1 {'id': 'ga4gh:VA.cXj8KP9BiAd7B0GVZQ-09h-UTWhGz... \n", + " 2 {'id': 'ga4gh:VA.Gf1VNPtWmRvR0nBzzkevvOxkSjTRj... \n", + " 3 {'id': 'ga4gh:VA.K2QuxjkfshnoDIrjdgvr4SwkdLdUb... \n", + " 4 {'id': 'ga4gh:VA.m9N_NCeX6I1mZOpiZfVsJc4rmUlVP... \n", " .. ... \n", - " 817 {'_id': 'ga4gh:VA.9fmVp-MJA0Y2WX9aU3R52KtEr4xK... \n", - " 818 {'_id': 'ga4gh:VA.djOD5yEL6aEvDykRXu-p54LYyx5S... \n", - " 819 {'_id': 'ga4gh:VA.BD4uu1pK7nQjDftZhw7TZBfcC9lr... \n", - " 820 {'_id': 'ga4gh:VA.TaAJRzE7gc0pYAWKlCHDjO0DyoL1... \n", - " 821 {'_id': 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... \n", - " 817 {'_id': 'ga4gh:VA.g04UFMxP4iAwrDMNrcqcqh344hzI... \n", - " 818 {'_id': 'ga4gh:VA.Dn6UK7PAIKSCYL4AKB0E37djStrf... \n", - " 819 {'_id': 'ga4gh:VA.4P9adviydsRxIDrSc_KOqqU6_81Q... \n", - " 820 {'_id': 'ga4gh:VA.ogZ_nXSdID2C2kER6SH3HPgiIAme... \n", - " 821 {'_id': 'ga4gh:VA.RRzVO4PFMlugvHibTfkIgfGdYuXL... \n", + " 817 {'id': 'ga4gh:VA.w6QBm_NJBtbTfcNhl1b3mt5paqAdi... \n", + " 818 {'id': 'ga4gh:VA.m2E2dNNQtPZdnnXP4Zpn-zuCk6OGS... \n", + " 819 {'id': 'ga4gh:VA.t0kS0-HSHJzdsiswCE34pqvWtEkSo... \n", + " 820 {'id': 'ga4gh:VA.qF0034d2bTnvIzki7OpSWfjFrL18u... \n", + " 821 {'id': 'ga4gh:VA.51X-6F6Ix2ARuFbIJ251Ni8Y-rVKn... \n", " \n", " [822 rows x 2 columns],\n", - " 'urn:mavedb:00000014-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.6pT9JotEJQJGLOFR5Oks5jI6-q3d... \n", - " 1 {'_id': 'ga4gh:VA.E8sYRkTphht0oXp4d_FFQWNMi2C1... \n", - " 2 {'_id': 'ga4gh:VA.YrK6M0vJjrEsSLzI4uWILHvGmMla... \n", - " 3 {'_id': 'ga4gh:VA.ILx07sqDWS_oEnYpXtwKh51gS4ca... \n", - " 4 {'_id': 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854 {'id': 'ga4gh:VA.L9yJKrCCg0lZcKrYw4NuL-yJE3GTU... \n", " \n", " [855 rows x 2 columns],\n", " 'urn:mavedb:00000007-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.gb21u-E-QBPM-zl9nI2_0ZVCRHxi... \n", - " 1 {'_id': 'ga4gh:VA.UtE7zeeawXaoBbGXx94r_khu-dVq... \n", - " 2 {'_id': 'ga4gh:VA.c8XX-9-nvwazMH_12wS-OXT2oHG8... \n", - " 3 {'_id': 'ga4gh:VA.4LoeRzrwBcU2Xm5CeSNcoy_DNE-Q... \n", - " 4 {'_id': 'ga4gh:VA.HJFTkvmuQKTlgZvZapYg_uwNUtBr... \n", + " 0 {'id': 'ga4gh:VA.ewC5Kkchppag4kUzh0TMe5s-TALJj... \n", + " 1 {'id': 'ga4gh:VA.3iTU2PbPfYpDroWKucwmFCEMPiMGP... \n", + " 2 {'id': 'ga4gh:VA.qZdjewvIzi-MmTgBh0VozyPZxQuSo... \n", + " 3 {'id': 'ga4gh:VA.agpkkHTXSz8fNKobhX4DciGFtTWKB... \n", + " 4 {'id': 'ga4gh:VA.7yYJBaWUdhJSrIF0CRH61kQarSXk3... \n", " ... ... \n", - " 1855 {'_id': 'ga4gh:VA.llFUHNENN6kmNzcrsrjZxSZQdvar... \n", - " 1856 {'_id': 'ga4gh:VA.scWB_cP_k3gKWJbCUMWXeblN-3qW... \n", - " 1857 {'_id': 'ga4gh:VA.e0rvSmi8sUnozRfFQOwXoL3ozRp4... \n", - " 1858 {'_id': 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\n", + " 3 {'id': 'ga4gh:VA.QTkrfgtekMDePjTcvgxctWZFzHe8b... \n", + " 4 {'id': 'ga4gh:VA.CA9bNzG9IA-DVNZogB5Ab4nMowU9u... \n", " ... ... \n", - " 1795 {'_id': 'ga4gh:VA.au7FnDCnMgvf4q_GdxWE-7Vg6ycw... \n", - " 1796 {'_id': 'ga4gh:VA.fjqBrS00OzZ4w9MOZrqIpDMngPdy... \n", - " 1797 {'_id': 'ga4gh:VA.5alTewGOtQr0FkiiHJk-zWGdilxU... \n", - " 1798 {'_id': 'ga4gh:VA.VYNuYM59GWvRe3g1bGIc1h2G6t8p... \n", - " 1799 {'_id': 'ga4gh:VA.iw1LsHGA1q4pNn8quuigfNKZOZfr... \n", + " 1795 {'id': 'ga4gh:VA.bewXTfPfbMGZSqfOG3_cQK5isFlDs... \n", + " 1796 {'id': 'ga4gh:VA.FR-eoEUMLRVjL9nSWXmUY8DiF1TxK... \n", + " 1797 {'id': 'ga4gh:VA.W1R5qpU8b-BlUj8SOeIKCBny6a1-0... \n", + " 1798 {'id': 'ga4gh:VA.BWIx9c5vBuu9Ox48q35oLz4rPt569... \n", + " 1799 {'id': 'ga4gh:VA.i7_pIrqYcDCPmDrHEzs7NSP0FrjIb... \n", " \n", " [1800 rows x 2 columns],\n", " 'urn:mavedb:00000029-b-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.H86PzJGZ8c-4KeUt-pHZ6CDX7jXL... \n", - " 1 {'_id': 'ga4gh:VA.q_stNM7u0MYdvIaYzwcskvrdCjoi... \n", - " 2 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" 1767 {'id': 'ga4gh:VA.WUNBwFXcQsvzC0hEsgMMxubvDbv2V... \n", + " 1768 {'id': 'ga4gh:VA.uWU_LDFL5Ybaq3t87mgwUSmAOrH_5... \n", + " 1769 {'id': 'ga4gh:VA.Ulr0fTw3rFF4RCcpp5HBUy50H3ko3... \n", " \n", " [1770 rows x 2 columns],\n", " 'urn:mavedb:00000034-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.refZsSRKsWTRmQ0KqJ5kyxKj40HP... \n", - " 1 {'_id': 'ga4gh:VA.N5rFBI1Bek330CQ6DphZmGJue-JT... \n", - " 2 {'_id': 'ga4gh:VA.uLfc5rDnc24zx1FTZQUxjPV1Ht0p... \n", - " 3 {'_id': 'ga4gh:VA.c6-BTXDzKKECEOLcgEoI-qr_HH0X... \n", - " 4 {'_id': 'ga4gh:VA.y6dfeuGlEyJKAEscjNAyA0jT2BuU... \n", + " 0 {'id': 'ga4gh:VA.lnnQZhpB3Ycq2rf9hIBYBSCmFdg_H... \n", + " 1 {'id': 'ga4gh:VA.GuhVTvxU6LBAg7GLFAQ1yy91_fEfP... \n", + " 2 {'id': 'ga4gh:VA.1u6VaIT9Igh1k7oYnEhWx9SPtS2Ci... \n", + " 3 {'id': 'ga4gh:VA.pB0QwXEkSmrPF-6diuBS8Tma-doql... \n", + " 4 {'id': 'ga4gh:VA.SN_NMiS8g9QYwowlU_3EezMDEEAlY... \n", " ... ... \n", - " 1450 {'_id': 'ga4gh:VA.vLeaUC_Jq-uawk-oFmPWZ3_KZ-jI... \n", - " 1451 {'_id': 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{'id': 'ga4gh:VA.CiIjXSme8dyR5nponSfCicChUmFHl... \n", + " 951 {'id': 'ga4gh:VA.Qbfu5LS06TtfyDuMMQt6jNaStuE4S... \n", + " 952 {'id': 'ga4gh:VA.3ebz7ntsD5tilTlOTy-vFnPHwn8PA... \n", + " 953 {'id': 'ga4gh:VA.6ooFNX0GC6KlhBk3eo0F7CVCgasRb... \n", " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.VB1MqvJqueAuOGbmQ2EKopidRxd2... \n", - " 1 {'_id': 'ga4gh:VA.3_lU-LU24ZRYm247YQ1N8Hwr37w2... \n", - " 2 {'_id': 'ga4gh:VA.ewe5b8FDzv3jMStGc_eUgoN_SvVE... \n", - " 3 {'_id': 'ga4gh:VA.idl2CT3f655ATpaE7oiGu8eeQMDs... \n", - " 4 {'_id': 'ga4gh:VA.Iw1YsrORpg3zE96KpfNt3mbN4c8-... \n", + " 0 {'id': 'ga4gh:VA.pTORP9NROdfSibB_aotzDhjD3tTke... \n", + " 1 {'id': 'ga4gh:VA.i-72CQpIC-hY_lHlqnEoJ8KAeiY2a... \n", + " 2 {'id': 'ga4gh:VA.guLtgmWfD7dZztOnklen6O4IPY7Gx... \n", + " 3 {'id': 'ga4gh:VA.RpkpfpjmMisxhV851YmQYyvTOMEx-... \n", + " 4 {'id': 'ga4gh:VA.AaFpTUuFwNxTO3MF1COf4h6y4u0AX... \n", " .. ... \n", - " 949 {'_id': 'ga4gh:VA.89giGwEO-yc9iMA5b3yHH6ZmgwmY... \n", - " 950 {'_id': 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'ga4gh:VA.g_WNOkxYeyVFi_QnxjjkUiWzFex9... \n", - " 551 {'_id': 'ga4gh:VA.OgQxl4P9c9CnxMWNnTiFW9DwG4SU... \n", - " 552 {'_id': 'ga4gh:VA.ycntPGzWbs70sZ7LNFuH6AUowgR3... \n", - " 553 {'_id': 'ga4gh:VA.xQMyCxwcGzlRCqKE_Ty1UXjw8y8o... \n", - " 554 {'_id': 'ga4gh:VA.q_yD-1OpqBomQGRI3_fzJnPVFMWd... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.PRKTthr4_IJ89rAB6ZkrWR_K1HbV... \n", - " 1 {'_id': 'ga4gh:VA.oMWFjdiHslrLbImd-bsdAmbW0hi2... \n", - " 2 {'_id': 'ga4gh:VA.S1wJepqrb4sN1EN5XBqOaC0LHhJC... \n", - " 3 {'_id': 'ga4gh:VA.2Mu7IuEdOad3-W4gOhQSmUspfT-m... \n", - " 4 {'_id': 'ga4gh:VA.oXzXrtKWbrhYBfxTfPYVm7DnAUYH... \n", - " .. ... \n", - " 550 {'_id': 'ga4gh:VA.ZqG1NlFeMnh8oesU2dZWKi-vdd2n... \n", - " 551 {'_id': 'ga4gh:VA.y0qTlKTZUdZAAY14G1ByzLwPPg0y... \n", - " 552 {'_id': 'ga4gh:VA.9lhi1NMpyaKfVIankqseKE8xCWC_... \n", - " 553 {'_id': 'ga4gh:VA.CEsQMo7mJqiWzSZWAMqyI59CYp6G... \n", - " 554 {'_id': 'ga4gh:VA.uUN1LYjNVKxVaJJ7xbTe_e8hNnMN... \n", - " \n", - " [555 rows x 2 columns],\n", - " 'urn:mavedb:00000024-a-1': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.3mdM4ad4F_OkjuH76qOdHak-FdSI... \n", - " 1 {'_id': 'ga4gh:VA.Db6MMu1vbe7j27u6ec5DYCfWmPGv... \n", - " 2 {'_id': 'ga4gh:VA.NoJ20nyTUBWczQERT8wOyrUhCrhz... \n", - " 3 {'_id': 'ga4gh:VA.Pn3WJjy6ddIiys6GmbRwMxfR89Cz... \n", - " 4 {'_id': 'ga4gh:VA.UD6WJxlgV_QaGfr_s-Z-8GU1-X7p... \n", - " ... ... \n", - " 1768 {'_id': 'ga4gh:VA.1rblzU4wOMHZ7_LiAbTQ23ucEMrb... \n", - " 1769 {'_id': 'ga4gh:VA.MmrBIfhEkRaE6O5UfWI26Bg10hqn... \n", - " 1770 {'_id': 'ga4gh:VA.R7ogPJazNEptmBr7brmdDeYcxfC9... \n", - " 1771 {'_id': 'ga4gh:VA.-49O0fXSrbld7pp6rd6f6ZT9YFEc... \n", - " 1772 {'_id': 'ga4gh:VA.l8RIkAxtlxutVqm-_2PvSY6JlmHl... \n", - " \n", - " mapped \n", - " 0 {'_id': 'ga4gh:VA.UgfbvROERtiJkYPitPZgSqcJBQkN... \n", - " 1 {'_id': 'ga4gh:VA.6LzOz5VYcRUE7G215XuD7xn4j0UT... \n", - " 2 {'_id': 'ga4gh:VA.ueq_LTlfyP4flwdXvm9QEauezAXs... \n", - " 3 {'_id': 'ga4gh:VA.UXBumJN000TJyLf3GW1alvmU6C2L... \n", - " 4 {'_id': 'ga4gh:VA.a0T7r9ut76MeY_cwTeu0PXZuH4vt... \n", - " ... ... \n", - " 1768 {'_id': 'ga4gh:VA.JI41RiYSHz2_aqCdf7TMxHn_Qwk8... \n", - " 1769 {'_id': 'ga4gh:VA.XAzHNotEfadkax0OKnFYLOHXIyHE... \n", - " 1770 {'_id': 'ga4gh:VA.KQMMNcySandTtGKiHbULJM5tfWHa... \n", - " 1771 {'_id': 'ga4gh:VA.72ikUbtjo7706j9rzd3G7UPuKLfE... \n", - " 1772 {'_id': 'ga4gh:VA.50TgYiHe8PaSIdgNvR9P4UO6x9x4... \n", - " \n", - " [1773 rows x 2 columns],\n", " 'urn:mavedb:00000029-a-2': pre_mapping \\\n", - " 0 {'_id': 'ga4gh:VA.y0VFORHYdKUJ4CP-_X-ySlKybTgQ... \n", - " 1 {'_id': 'ga4gh:VA.xLz_tyMsJ5jqBxlH7E07tIM40Un9... \n", - " 2 {'_id': 'ga4gh:VA.z-IspnvdWlUbj3rxWVTux9_wUxIg... \n", - " 3 {'_id': 'ga4gh:VA.K-d-Rcag2Ro5XfY_WOKwSSOUclFJ... \n", - " 4 {'_id': 'ga4gh:VA.BjgbOZS0fBW-wc0PNcz-YXjxvCeU... \n", + " 0 {'id': 'ga4gh:VA.sf20_ihYkCXOW-eVtkXXROdsP-72P... \n", + " 1 {'id': 'ga4gh:VA.hrn2rTpSbVMWu5IWhQb9b2dyiqBx8... \n", + " 2 {'id': 'ga4gh:VA.m4gw9V5ml3aKCNAde9JuYALc5UV3y... \n", + " 3 {'id': 'ga4gh:VA.u2pUTbLYRye1awCpLtEWLfpyUXIUe... \n", + " 4 {'id': 'ga4gh:VA.Jw0O-eU_zkuEoh8MpAp9H8__PxXmM... \n", " ... ... \n", - " 1793 {'_id': 'ga4gh:VA.WM4_nuBJMzXVQxh01OeRxa25hSLk... \n", - " 1794 {'_id': 'ga4gh:VA.6hOkhv1NOvox27apnbNEbG9qimxk... \n", - " 1795 {'_id': 'ga4gh:VA.Swp32f3kTSspPn7Nif4XHsunD4_B... \n", - " 1796 {'_id': 'ga4gh:VA.Tgc9XUrsNU72y7-l5h7vZuIoGLwY... \n", - " 1797 {'_id': 'ga4gh:VA.cUxCvmhSmWZKRJO5ikElqSCAkeMN... \n", + " 1793 {'id': 'ga4gh:VA.aILVRRDZHdEGi-T_XY4e09LM0c_WQ... \n", + " 1794 {'id': 'ga4gh:VA.dwv343iTdmQSVAj6BbKaG6__-rPbK... \n", + " 1795 {'id': 'ga4gh:VA.bm65IPzMoInJX6nk6jmLHfX0fTgFa... \n", + " 1796 {'id': 'ga4gh:VA.I3KIabPCzZLY5Qz8jKku3GgkR9CMJ... \n", + " 1797 {'id': 'ga4gh:VA.wLpfah7fK2C6asbZEe--rTopz2R9S... \n", " \n", " mapped \n", - " 0 {'_id': 'ga4gh:VA.fOLhdhtKMWvA5kNekmB55SrfKsay... \n", - " 1 {'_id': 'ga4gh:VA.f9WPxUL_3hOG8RLzEXJvR5naEyg4... \n", - " 2 {'_id': 'ga4gh:VA.4u7t4OI6xE7zR4QStFfvgOTU2XmB... \n", - " 3 {'_id': 'ga4gh:VA.2Q0wcO3EujXr8lixf2YjiHyu-v_c... \n", - " 4 {'_id': 'ga4gh:VA.IiWFKEKrNAglBVRxUukhvUMr8kwt... \n", + " 0 {'id': 'ga4gh:VA.JDfPubJjmK3aidfYv_l15GW6rpxd0... \n", + " 1 {'id': 'ga4gh:VA.G0AmQ1QRsEyPIvARihre7KY17TT7G... \n", + " 2 {'id': 'ga4gh:VA.kPgC5AEdhWnYYV2gdDV5dfAXFBwhp... \n", + " 3 {'id': 'ga4gh:VA.KTMqXe7bTUVTglZGzHtebdCk2X-Km... \n", + " 4 {'id': 'ga4gh:VA.kLScfwjGcZVcGCtd9bP6AnMxZ7CKK... \n", " ... ... \n", - " 1793 {'_id': 'ga4gh:VA.wMQr1iwV0YXEpCaJSB484jeVenpw... \n", - " 1794 {'_id': 'ga4gh:VA.0hQwbPhK9rQdN7oXXot7BCZXX4Qt... \n", - " 1795 {'_id': 'ga4gh:VA.2xosiQVuDqI9n_kMiLGrMgneGbyn... \n", - " 1796 {'_id': 'ga4gh:VA.dJjgoHWTFSJL6HmKW5DvizwEc0ZD... \n", - " 1797 {'_id': 'ga4gh:VA.xA4wUEfrWca8-2Y6E0U_p5_AMSrr... \n", + " 1793 {'id': 'ga4gh:VA.jqPGxeHWFoE3qSSRH3wHI-Jabntv9... \n", + " 1794 {'id': 'ga4gh:VA.oW9KA4W0eNgCDWuNF5JOHEKYlFZiT... \n", + " 1795 {'id': 'ga4gh:VA.xt6w7J54HVsjENPz2QWUsF5oROZih... \n", + " 1796 {'id': 'ga4gh:VA.qNa33a1F0UruRa8yj3uKenLyOJEim... \n", + " 1797 {'id': 'ga4gh:VA.n7gXWkkWGfAc-dj6d0qW2BbI5xM2E... \n", " \n", " [1798 rows x 2 columns]}" ] }, - "execution_count": 16, + "execution_count": 4, "metadata": {}, "output_type": "execute_result" } @@ -9293,9 +13703,13 @@ "source": [ "# VRS variant mapping non-protein coding scoresets\n", "dp = SeqRepoDataProxy(sr = sr)\n", - "tr = Translator(data_proxy = dp)\n", + "tr = Translator(data_proxy = dp, normalize = False)\n", "qh = QueryHandler()\n", "vrs_noncoding_mappings_dict = {}\n", + "scores_dict_noncoding = {}\n", + "\n", + "mave_dat = pd.read_csv('results/mave_dat.csv')\n", + "dat = mave_dat\n", "\n", "for i in range(len(dat.index)):\n", " if dat.at[i, 'target_type'] != 'Protein coding':\n", @@ -9316,26 +13730,81 @@ " \n", " var_ids_pre_map = []\n", " var_ids_post_map = []\n", + " ranges = get_locs_list(item['hits'])\n", " ref = get_chr(dp, item['chrom'])\n", - " offset = ranges[0]\n", + " hits = get_hits_list(item['hits'])\n", + " strand = mave_blat_dict[dat.at[i, 'urn']]['strand']\n", + " \n", " ts = dat.at[i, 'target_sequence']\n", + " digest = 'SQ.' + sha512t24u(ts.encode('ascii'))\n", + " alias_dict_list = [{'namespace': 'ga4gh', 'alias': digest}]\n", + " sr.store(ts, nsaliases = alias_dict_list) # Add custom digest to SeqRepo\n", + " \n", + " scores = varsdat['score'].to_list()\n", + " scores_list = []\n", "\n", " for j in range(len(ntlist)):\n", " if '=' in ntlist[j] or ntlist[j] == '_wt' or ntlist[j] == '_sy':\n", " continue\n", " else:\n", " try:\n", - " var_ids_pre_map.append(get_haplotype_allele(ntlist[j][2:], ref, 0, 'g', tr, dp, ts, 'pre').as_dict())\n", - " var_ids_post_map.append(get_haplotype_allele(ntlist[j][2:], ref, offset, 'g', tr, dp, ts, 'post').as_dict())\n", + " var_ids_pre_map.append(get_haplotype_allele(ntlist[j][2:], ref, 0, 'g', tr, dp, ts, 'pre', ranges, hits, strand).as_dict())\n", + " var_ids_post_map.append(get_haplotype_allele(ntlist[j][2:], ref, 0, 'g', tr, dp, ts, 'post', ranges, hits, strand).as_dict())\n", + " scores_list.append(scores[j])\n", " except:\n", " continue\n", - "\n", + " \n", " tempdat = pd.DataFrame({'pre_mapping': var_ids_pre_map, 'mapped': var_ids_post_map})\n", " vrs_noncoding_mappings_dict[dat.at[i, 'urn']] = tempdat\n", + " scores_dict_noncoding[dat.at[i, 'urn']] = scores_list\n", "\n", "vrs_noncoding_mappings_dict" ] }, + { + "cell_type": "code", + "execution_count": 18, + "id": "9c0cbec6", + "metadata": {}, + "outputs": [], + "source": [ + "with open('results/vrs_mappings_coding_normalize_false.pickle', 'wb') as fn:\n", + " pickle.dump(vrs_mappings_dict, fn, protocol=pickle.HIGHEST_PROTOCOL)" + ] + }, + { + "cell_type": "code", + "execution_count": 19, + "id": "4432a1f5", + "metadata": {}, + "outputs": [], + "source": [ + "with open('results/scores_coding.pickle', 'wb') as fn:\n", + " pickle.dump(scores_dict_coding, fn, protocol=pickle.HIGHEST_PROTOCOL)" + ] + }, + { + "cell_type": "code", + "execution_count": 20, + "id": "f2faf010", + "metadata": {}, + "outputs": [], + "source": [ + "with open('results/vrs_mappings_noncoding_normalize_false.pickle', 'wb') as fn:\n", + " pickle.dump(vrs_noncoding_mappings_dict, fn, protocol=pickle.HIGHEST_PROTOCOL)" + ] + }, + { + "cell_type": "code", + "execution_count": 21, + "id": "c2daea2d", + "metadata": {}, + "outputs": [], + "source": [ + "with open('results/scores_noncoding.pickle', 'wb') as fn:\n", + " pickle.dump(scores_dict_noncoding, fn, protocol=pickle.HIGHEST_PROTOCOL)" + ] + }, { "cell_type": "code", "execution_count": 17, @@ -9346,16 +13815,16 @@ "name": "stdout", "output_type": "stream", "text": [ - "{'_id': 'ga4gh:VA.mEeUxPTsYR3nv2HatnR0fVPAN4whv_Vw', 'type': 'Allele', 'location': {'type': 'SequenceLocation', 'sequence_id': 'ga4gh:SQ.PyX9IDu95_tYLg1Jz9JpW5xpQkwn6bpB', 'interval': {'type': 'SequenceInterval', 'start': {'type': 'Number', 'value': 14}, 'end': {'type': 'Number', 'value': 15}}}, 'state': {'type': 'LiteralSequenceExpression', 'sequence': 'H'}}\n", - "{'_id': 'ga4gh:VA.NXnq2B9h0OLVbKfqGRoDLkf4Mqc0tKOP', 'type': 'Allele', 'location': {'type': 'SequenceLocation', 'sequence_id': 'ga4gh:SQ.uJDQo_HaTNFL2-0-6K5dVzVcweigexye', 'interval': {'type': 'SequenceInterval', 'start': {'type': 'Number', 'value': 283}, 'end': {'type': 'Number', 'value': 284}}}, 'state': {'type': 'LiteralSequenceExpression', 'sequence': 'H'}}\n", - "{'_id': 'ga4gh:VA.H0UXotsEF90OQKPLEsiuRbUkHCWgaW0q', 'type': 'Allele', 'location': {'type': 'SequenceLocation', 'sequence_id': 'ga4gh:SQ.jUOcLPDjSqWFEo9kSOG8ITe1dr9QK3h6', 'interval': {'type': 'SequenceInterval', 'start': {'type': 'Number', 'value': 2}, 'end': {'type': 'Number', 'value': 3}}}, 'state': {'type': 'LiteralSequenceExpression', 'sequence': 'G'}}\n", - "{'_id': 'ga4gh:VA.SBgaQ-fz9q0vSXtP9QDWZqmb0zrmnwx7', 'type': 'Allele', 'location': {'type': 'SequenceLocation', 'sequence_id': 'ga4gh:SQ.2NkFm8HK88MqeNkCgj78KidCAXgnsfV1', 'interval': {'type': 'SequenceInterval', 'start': {'type': 'Number', 'value': 5227023}, 'end': {'type': 'Number', 'value': 5227024}}}, 'state': {'type': 'LiteralSequenceExpression', 'sequence': 'G'}}\n" + "{'id': 'ga4gh:VA.K7JuB0HAfN875G9YyQvnjWCH1STCY3XW', 'type': 'Allele', 'location': {'type': 'SequenceLocation', 'sequence_id': 'ga4gh:SQ.PyX9IDu95_tYLg1Jz9JpW5xpQkwn6bpB', 'start': {'type': 'Number', 'value': 14}, 'end': {'type': 'Number', 'value': 15}}, 'state': {'type': 'LiteralSequenceExpression', 'sequence': 'H'}}\n", + "{'id': 'ga4gh:VA.HCOcTdM8eXArAEOy257kJuc95d-UBP2i', 'type': 'Allele', 'location': {'type': 'SequenceLocation', 'sequence_id': 'ga4gh:SQ.uJDQo_HaTNFL2-0-6K5dVzVcweigexye', 'start': {'type': 'Number', 'value': 283}, 'end': {'type': 'Number', 'value': 284}}, 'state': {'type': 'LiteralSequenceExpression', 'sequence': 'H'}}\n", + "{'id': 'ga4gh:VA.aL2vPNTYMmCg2AlvBxo6Z2JKkDSS7n1B', 'type': 'Allele', 'location': {'type': 'SequenceLocation', 'sequence_id': 'ga4gh:SQ.jUOcLPDjSqWFEo9kSOG8ITe1dr9QK3h6', 'start': {'type': 'Number', 'value': 2}, 'end': {'type': 'Number', 'value': 3}}, 'state': {'type': 'LiteralSequenceExpression', 'sequence': 'G'}}\n", + "{'id': 'ga4gh:VA.cEAoxVpV2kD6LPSInjaGs6ZBNbxSpYed', 'type': 'Allele', 'location': {'type': 'SequenceLocation', 'sequence_id': 'ga4gh:SQ.2NkFm8HK88MqeNkCgj78KidCAXgnsfV1', 'start': {'type': 'Number', 'value': 5227023}, 'end': {'type': 'Number', 'value': 5227024}}, 'state': {'type': 'LiteralSequenceExpression', 'sequence': 'G'}}\n" ] } ], "source": [ - "# Variant Mapping Example - Coding and Noncoding\n", - "ex = vrs_mappings_dict['urn:mavedb:00000041-a-1']\n", + "# Variant Mapping Example - Coding,Noncoding,Protein + Genomic\n", + "ex = vrs_mappings_dict['urn:mavedb:00000041-a-1'][0]\n", "print(ex.at[0, 'pre_mapping'])\n", "print(ex.at[0, 'mapped'])\n", "\n", @@ -9363,6 +13832,73 @@ "print(ex.at[0, 'pre_mapping'])\n", "print(ex.at[0, 'mapped'])" ] + }, + { + "cell_type": "markdown", + "id": "f3ad683a", + "metadata": {}, + "source": [ + "# The blocks below can be run to access the output in the results directory" + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "id": "4e5ae5b6", + "metadata": {}, + "outputs": [], + "source": [ + "# Load metadata\n", + "mave_dat = pd.read_csv('results/mave_dat.csv')" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "id": "201f3aef", + "metadata": {}, + "outputs": [], + "source": [ + "# Load alignment data\n", + "with open('results/mave_blat.pickle', 'rb') as fn:\n", + " mave_blat_dict = pickle.load(fn)" + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "id": "18bdefde", + "metadata": {}, + "outputs": [], + "source": [ + "# Load mappings data\n", + "with open('results/mappings.pickle', 'rb') as fn:\n", + " mappings_dict = pickle.load(fn)" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "id": "1ba2cf09", + "metadata": {}, + "outputs": [], + "source": [ + "# Load coding data\n", + "with open('results/vrs_mappings_coding_normalize_false.pickle', 'rb') as fn:\n", + " vrs_mappings_coding = pickle.load(fn)" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "id": "0ea50429", + "metadata": {}, + "outputs": [], + "source": [ + "# Load noncoding data\n", + "with open('results/vrs_mappings_noncoding_normalize_false.pickle', 'rb') as fn:\n", + " vrs_mappings_noncoding = pickle.load(fn)" + ] } ], "metadata": { @@ -9381,7 +13917,7 @@ "name": "python", "nbconvert_exporter": "python", "pygments_lexer": "ipython3", - "version": "3.8.9" + "version": "3.10.3" } }, "nbformat": 4, diff --git a/notebooks/analysis/results/mappings.pickle b/notebooks/analysis/results/mappings.pickle new file mode 100644 index 0000000..4f0ec10 Binary files /dev/null and b/notebooks/analysis/results/mappings.pickle differ diff --git a/notebooks/analysis/results/mave_blat.pickle b/notebooks/analysis/results/mave_blat.pickle new file mode 100644 index 0000000..d556d65 Binary files /dev/null and b/notebooks/analysis/results/mave_blat.pickle differ diff --git a/notebooks/analysis/results/mave_dat.csv b/notebooks/analysis/results/mave_dat.csv new file mode 100644 index 0000000..c8b170e --- /dev/null +++ b/notebooks/analysis/results/mave_dat.csv @@ -0,0 +1,210 @@ +,urn,target_sequence,target_sequence_type,target,assembly_id,uniprot_id,target_type +0,urn:mavedb:00000041-a-1,CTGCGGCTGGAGGTCAAGCTGGGCCAGGGCTGCTTTGGCGAGGTGTGGATGGGGACCTGGAACGGTACCACCAGGGTGGCCATCAAAACCCTGAAGCCTGGCACGATGTCTCCAGAGGCCTTCCTGCAGGAGGCCCAGGTCATGAAGAAGCTGAGGCATGAGAAGCTGGTGCAGTTGTATGCTGTGGTTTCAGAGGAGCCCATTTACATCGTCACGGAGTACATGAGCAAGGGGAGTTTGCTGGACTTTCTCAAGGGGGAGACAGGCAAGTACCTGCGGCTGCCTCAGCTGGTGGACATGGCTGCTCAGATCGCCTCAGGCATGGCGTACGTGGAGCGGATGAACTACGTCCACCGGGACCTTCGTGCAGCCAACATCCTGGTGGGAGAGAACCTGGTGTGCAAAGTGGCCGACTTTGGGCTGGCTCGGCTCATTGAAGACAATGAGTACACGGCGCGGCAAGGTGCCAAATTCCCCATCAAGTGGACGGCTCCAGAAGCTGCCCTCTATGGCCGCTTCACCATCAAGTCGGACGTGTGGTCCTTCGGGATCCTGCTGACTGAGCTCACCACAAAGGGACGGGTGCCCTACCCTGGGATGGTGAACCGCGAGGTGCTGGACCAGGTGGAGCGGGGCTACCGGATGCCCTGCCCGCCGGAGTGTCCCGAGTCCCTGCACGACCTCATGTGCCAGTGCTGGCGGAAGGAGCCTGAGGAGCGGCCCACCTTCGAGTACCTGCAGGCCTTCCTG,dna,Src catalytic domain,GCF_000001405.26,P12931,Protein coding +1,urn:mavedb:00000048-a-1,GAGGGGATCAGTATATACACTTCAGATAACTACACCGAGGAAATGGGCTCAGGGGACTATGACTCCATGAAGGAACCCTGTTTCCGTGAAGAAAATGCTAATTTCAATAAAATCTTCCTGCCCACCATCTACTCCATCATCTTCTTAACTGGCATTGTGGGCAATGGATTGGTCATCCTGGTCATGGGTTACCAGAAGAAACTGAGAAGCATGACGGACAAGTACAGGCTGCACCTGTCAGTGGCCGACCTCCTCTTTGTCATCACGCTTCCCTTCTGGGCAGTTGATGCCGTGGCAAACTGGTACTTTGGGAACTTCCTATGCAAGGCAGTCCATGTCATCTACACAGTCAACCTCTACAGCAGTGTCCTCATCCTGGCCTTCATCAGTCTGGACCGCTACCTGGCCATCGTCCACGCCACCAACAGTCAGAGGCCAAGGAAGCTGTTGGCTGAAAAGGTGGTCTATGTTGGCGTCTGGATCCCTGCCCTCCTGCTGACTATTCCCGACTTCATCTTTGCCAACGTCAGTGAGGCAGATGACAGATATATCTGTGACCGCTTCTACCCCAATGACTTGTGGGTGGTTGTGTTCCAGTTTCAGCACATCATGGTTGGCCTTATCCTGCCTGGTATTGTCATCCTGTCCTGCTATTGCATTATCATCTCCAAGCTGTCACACTCCAAGGGCCACCAGAAGCGCAAGGCCCTCAAGACCACAGTCATCCTCATCCTGGCTTTCTTCGCCTGTTGGCTGCCTTACTACATTGGGATCAGCATCGACTCCTTCATCCTCCTGGAAATCATCAAGCAAGGGTGTGAGTTTGAGAACACTGTGCACAAGTGGATTTCCATCACCGAGGCCCTAGCTTTCTTCCACTGTTGTCTGAACCCCATCCTCTATGCTTTCCTTGGAGCCAAATTTAAAACCTCTGCCCAGCACGCACTCACCTCTGTGAGCAGAGGGTCCAGCCTCAAGATCCTCTCCAAAGGAAAGCGAGGTGGACATTCATCTGTTTCCACTGAGTCTGAGTCTTCAAGTTTTCACTCCAGC,dna,CXCR4,GCF_000001405.26,P61073,Protein coding +2,urn:mavedb:00000068-b-1,ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAACGTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCAGATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCGCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCCTGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAGTCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACACCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAGCGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAACACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGTTCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGTGGTAATCTACTGGGACGGAACAGCTTTGAGGTGCGTGTTTGTGCCTGTCCTGGGAGAGACCGGCGCACAGAGGAAGAGAATCTCCGCAAGAAAGGGGAGCCTCACCACGAGCTGCCCCCAGGGAGCACTAAGCGAGCACTGCCCAACAACACCAGCTCCTCTCCCCAGCCAAAGAAGAAACCACTGGATGGAGAATATTTCACCCTTCAGATCCGTGGGCGTGAGCGCTTCGAGATGTTCCGAGAGCTGAATGAGGCCTTGGAACTCAAGGATGCCCAGGCTGGGAAGGAGCCAGGGGGGAGCAGGGCTCACTCCAGCCACCTGAAGTCCAAAAAGGGTCAGTCTACCTCCCGCCATAAAAAACTCATGTTCAAGACAGAAGGGCCTGACTCAGACTAG,dna,TP53 (P72R),GCF_000001405.26,,Protein coding +3,urn:mavedb:00000045-c-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +4,urn:mavedb:00000018-a-1,GGTGTCTGTTTGAGGTTGCTAGTGAACACAGTTGTGTCAGAAGCAAATGTAAGCAATAGATGGCTCTGCCCTGACTTTTATGCCCAGCCCTGGCTCCTGCCCTCCCTGCTCCTGGGAGTAGATTGGCCAACCCTAGGGTGTGGCTCCACAGGGTGAGGTCTAAGTGATGACAGCCGTACCTGTCCTT,dna,HBB promoter,GCF_000001405.26,,Regulatory +5,urn:mavedb:00000099-a-1,ATGAATGGCACAGAAGGCCCTAACTTCTACGTGCCCTTCTCCAATGCGACGGGTGTGGTACGCAGCCCCTTCGAGTACCCACAGTACTACCTGGCTGAGCCATGGCAGTTCTCCATGCTGGCCGCCTACATGTTTCTGCTGATCGTGCTGGGCTTCCCCATCAACTTCCTCACGCTCTACGTCACCGTCCAGCACAAGAAGCTGCGCACGCCTCTCAACTACATCCTGCTCAACCTAGCCGTGGCTGACCTCTTCATGGTCCTAGGTGGCTTCACCAGCACCCTCTACACCTCTCTGCATGGATACTTCGTCTTCGGGCCCACAGGATGCAATTTGGAGGGCTTCTTTGCCACCCTGGGCGGTGAAATTGCCCTGTGGTCCTTGGTGGTCCTGGCCATCGAGCGGTACGTGGTGGTGTGTAAGCCCATGAGCAACTTCCGCTTCGGGGAGAACCATGCCATCATGGGCGTTGCCTTCACCTGGGTCATGGCGCTGGCCTGCGCCGCACCCCCACTCGCCGGCTGGTCCAGGTACATCCCCGAGGGCCTGCAGTGCTCGTGTGGAATCGACTACTACACGCTCAAGCCGGAGGTCAACAACGAGTCTTTTGTCATCTACATGTTCGTGGTCCACTTCACCATCCCCATGATTATCATCTTTTTCTGCTATGGGCAGCTCGTCTTCACCGTCAAGGAGGCCGCTGCCCAGCAGCAGGAGTCAGCCACCACACAGAAGGCAGAGAAGGAGGTCACCCGCATGGTCATCATCATGGTCATCGCTTTCCTGATCTGCTGGGTGCCCTACGCCAGCGTGGCATTCTACATCTTCACCCACCAGGGCTCCAACTTCGGTCCCATCTTCATGACCATCCCAGCGTTCTTTGCCAAGAGCGCCGCCATCTACAACCCTGTCATCTATATCATGATGAACAAGCAGTTCCGGAACTGCATGCTCACCACCATCTGCTGCGGCAAGAACCCACTGGGTGACGATGAGGCCTCTGCTACCGTGTCCAAGACGGAGACGAGCCAGGTGGCCCCGGCCTAA,dna,RHO,GCF_000001405.26,,Protein coding +6,urn:mavedb:00000001-c-1,ATGGCTGATCAGCTGACCGAAGAACAGATTGCTGAATTCAAGGAAGCCTTCTCCCTATTTGATAAAGATGGCGATGGCACCATCACAACAAAGGAACTTGGAACTGTCATGAGGTCACTGGGTCAGAACCCAACAGAAGCTGAATTGCAGGATATGATCAATGAAGTGGATGCTGATGGTAATGGCACCATTGACTTCCCCGAATTTTTGACTATGATGGCTAGAAAAATGAAAGATACAGATAGTGAAGAAGAAATCCGTGAGGCATTCCGAGTCTTTGACAAGGATGGCAATGGTTATATCAGTGCAGCAGAACTACGTCACGTCATGACAAACTTAGGAGAAAAACTAACAGATGAAGAAGTAGATGAAATGATCAGAGAAGCAGATATTGATGGAGACGGACAAGTCAACTATGAAGAATTCGTACAGATGATGACTGCAAAATGA,dna,CALM1,GCF_000001405.26,P0DP23,Protein coding +7,urn:mavedb:00000049-a-3,ATGGTGAACGAAGCCAGAGGAAACAGCAGCCTCAACCCCTGCTTGGAGGGCAGTGCCAGCAGTGGCAGTGAGAGCTCCAAAGATAGTTCGAGATGTTCCACCCCGGGCCTGGACCCCGAGCGGCATGAGAGACTCCGGGAGAAGATGAGGCGGCGATTGGAATCTGGTGACAAGTGGTTCTCCCTGGAATTCTTCCCTCCTCGAACTGCTGAGGGAGCTGTCAATCTCATCTCAAGGTTTGACCGGATGGCAGCAGGTGGCCCCCTCTACATAGACGTGACCTGGCACCCAGCAGGTGACCCTGGCTCAGACAAGGAGACCTCCTCCATGATGATCGCCAGCACCGCCGTGAACTACTGTGGCCTGGAGACCATCCTGCACATGACCTGCTGCCGTCAGCGCCTGGAGGAGATCACGGGCCATCTGCACAAAGCTAAGCAGCTGGGCCTGAAGAACATCATGGCGCTGCGGGGAGACCCAATAGGTGACCAGTGGGAAGAGGAGGAGGGAGGCTTCAACTACGCAGTGGACCTGGTGAAGCACATCCGAAGTGAGTTTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCGAAGCAGGGAGCTTTGAGGCTGACCTGAAGCACTTGAAGGAGAAGGTGTCTGCGGGAGCCGATTTCATCATCACGCAGCTTTTCTTTGAGGCTGACACATTCTTCCGCTTTGTGAAGGCATGCACCGACATGGGCATCACTTGCCCCATCGTCCCCGGGATCTTTCCCATCCAGGGCTACCACTCCCTTCGGCAGCTTGTGAAGCTGTCCAAGCTGGAGGTGCCACAGGAGATCAAGGACGTGATTGAGCCAATCAAAGACAACGATGCTGCCATCCGCAACTATGGCATCGAGCTGGCCGTGAGCCTGTGCCAGGAGCTTCTGGCCAGTGGCTTGGTGCCAGGCCTCCACTTCTACACCCTCAACCGCGAGATGGCTACCACAGAGGTGCTGAAGCGCCTGGGGATGTGGACTGAGGACCCCAGGCGTCCCCTACCCTGGGCTCTCAGCGCCCACCCCAAGCGCCGAGAGGAAGATGTACGTCCCATCTTCTGGGCCTCCAGACCAAAGAGTTACATCTACCGTACCCAGGAGTGGGACGAGTTCCCTAACGGCCGCTGGGGCAATTCCTCTTCCCCTGCCTTTGGGGAGCTGAAGGACTACTACCTCTTCTACCTGAAGAGCAAGTCCCCCAAGGAGGAGCTGCTGAAGATGTGGGGGGAGGAGCTGACCAGTGAAGAAAGTGTCTTTGAAGTCTTCGTTCTTTACCTCTCGGGAGAACCAAACCGGAATGGTCACAAAGTGACTTGCCTGCCCTGGAACGATGAGCCCCTGGCGGCTGAGACCAGCCTGCTGAAGGAGGAGCTGCTGCGGGTGAACCGCCAGGGCATCCTCACCATCAACTCACAGCCCAACATCAACGGGAAGCCGTCCTCCGACCCCATCGTGGGCTGGGGCCCCAGCGGGGGCTATGTCTTCCAGAAGGCCTACTTAGAGTTTTTCACTTCCCGCGAGACAGCGGAAGCACTTCTGCAAGTGCTGAAGAAGTACGAGCTCCGGGTTAATTACCACCTTGTCAATGTGAAGGGTGAAAACATCACCAATGCCCCTGAACTGCAGCCGAATGCTGTCACTTGGGGCATCTTCCCTGGGCGAGAGATCATCCAGCCCACCGTAGTGGATCCCGTCAGCTTCATGTTCTGGAAGGACGAGGCCTTTGCCCTGTGGATTGAGCGGTGGGGAAAGCTGTATGAGGAGGAGTCCCCGTCCCGCACCATCATCCAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAATGACTTCCCACTGGACAACTGCCTCTGGCAGGTGGTGGAAGACACATTGGAGCTTCTCAACAGGCCCACCCAGAATGCGAGAGAAACGGAGGCTCCATGA,dna,MTHFR,GCF_000001405.26,P42898,Protein coding +8,urn:mavedb:00000050-a-1,ATGGCGGTGCAGCCGAAGGAGACGCTGCAGTTGGAGAGCGCGGCCGAGGTCGGCTTCGTGCGCTTCTTTCAGGGCATGCCGGAGAAGCCGACCACCACAGTGCGCCTTTTCGACCGGGGCGACTTCTATACGGCGCACGGCGAGGACGCGCTGCTGGCCGCCCGGGAGGTGTTCAAGACCCAGGGGGTGATCAAGTACATGGGGCCGGCAGGAGCAAAGAATCTGCAGAGTGTTGTGCTTAGTAAAATGAATTTTGAATCTTTTGTAAAAGATCTTCTTCTGGTTCGTCAGTATAGAGTTGAAGTTTATAAGAATAGAGCTGGAAATAAGGCATCCAAGGAGAATGATTGGTATTTGGCATATAAGGCTTCTCCTGGCAATCTCTCTCAGTTTGAAGACATTCTCTTTGGTAACAATGATATGTCAGCTTCCATTGGTGTTGTGGGTGTTAAAATGTCCGCAGTTGATGGCCAGAGACAGGTTGGAGTTGGGTATGTGGATTCCATACAGAGGAAACTAGGACTGTGTGAATTCCCTGATAATGATCAGTTCTCCAATCTTGAGGCTCTCCTCATCCAGATTGGACCAAAGGAATGTGTTTTACCCGGAGGAGAGACTGCTGGAGACATGGGGAAACTGAGACAGATAATTCAAAGAGGAGGAATTCTGATCACAGAAAGAAAAAAAGCTGACTTTTCCACAAAAGACATTTATCAGGACCTCAACCGGTTGTTGAAAGGCAAAAAGGGAGAGCAGATGAATAGTGCTGTATTGCCAGAAATGGAGAATCAGGTTGCAGTTTCATCACTGTCTGCGGTAATCAAGTTTTTAGAACTCTTATCAGATGATTCCAACTTTGGACAGTTTGAACTGACTACTTTTGACTTCAGCCAGTATATGAAATTGGATATTGCAGCAGTCAGAGCCCTTAACCTTTTTCAGGGTTCTGTTGAAGATACCACTGGCTCTCAGTCTCTGGCTGCCTTGCTGAATAAGTGTAAAACCCCTCAAGGACAAAGACTTGTTAACCAGTGGATTAAGCAGCCTCTCATGGATAAGAACAGAATAGAGGAGAGATTGAATTTAGTGGAAGCTTTTGTAGAAGATGCAGAATTGAGGCAGACTTTACAAGAAGATTTACTTCGTCGATTCCCAGATCTTAACCGACTTGCCAAGAAGTTTCAAAGACAAGCAGCAAACTTACAAGATTGTTACCGACTCTATCAGGGTATAAATCAACTACCTAATGTTATACAGGCTCTGGAAAAACATGAAGGAAAACACCAGAAATTATTGTTGGCAGTTTTTGTGACTCCTCTTACTGATCTTCGTTCTGACTTCTCCAAGTTTCAGGAAATGATAGAAACAACTTTAGATATGGATCAGGTGGAAAACCATGAATTCCTTGTAAAACCTTCATTTGATCCTAATCTCAGTGAATTAAGAGAAATAATGAATGACTTGGAAAAGAAGATGCAGTCAACATTAATAAGTGCAGCCAGAGATCTTGGCTTGGACCCTGGCAAACAGATTAAACTGGATTCCAGTGCACAGTTTGGATATTACTTTCGTGTAACCTGTAAGGAAGAAAAAGTCCTTCGTAACAATAAAAACTTTAGTACTGTAGATATCCAGAAGAATGGTGTTAAATTTACCAACAGCAAATTGACTTCTTTAAATGAAGAGTATACCAAAAATAAAACAGAATATGAAGAAGCCCAGGATGCCATTGTTAAAGAAATTGTCAATATTTCTTCAGGCTATGTAGAACCAATGCAGACACTCAATGATGTGTTAGCTCAGCTAGATGCTGTTGTCAGCTTTGCTCACGTGTCAAATGGAGCACCTGTTCCATATGTACGACCAGCCATTTTGGAGAAAGGACAAGGAAGAATTATATTAAAAGCATCCAGGCATGCTTGTGTTGAAGTTCAAGATGAAATTGCATTTATTCCTAATGACGTATACTTTGAAAAAGATAAACAGATGTTCCACATCATTACTGGCCCCAATATGGGAGGTAAATCAACATATATTCGACAAACTGGGGTGATAGTACTCATGGCCCAAATTGGGTGTTTTGTGCCATGTGAGTCAGCAGAAGTGTCCATTGTGGACTGCATCTTAGCCCGAGTAGGGGCTGGTGACAGTCAATTGAAAGGAGTCTCCACGTTCATGGCTGAAATGTTGGAAACTGCTTCTATCCTCAGGTCTGCAACCAAAGATTCATTAATAATCATAGATGAATTGGGAAGAGGAACTTCTACCTACGATGGATTTGGGTTAGCATGGGCTATATCAGAATACATTGCAACAAAGATTGGTGCTTTTTGCATGTTTGCAACCCATTTTCATGAACTTACTGCCTTGGCCAATCAGATACCAACTGTTAATAATCTACATGTCACAGCACTCACCACTGAAGAGACCTTAACTATGCTTTATCAGGTGAAGAAAGGTGTCTGTGATCAAAGTTTTGGGATTCATGTTGCAGAGCTTGCTAATTTCCCTAAGCATGTAATAGAGTGTGCTAAACAGAAAGCCCTGGAACTTGAGGAGTTTCAGTATATTGGAGAATCGCAAGGATATGATATCATGGAACCAGCAGCAAAGAAGTGCTATCTGGAAAGAGAGCAAGGTGAAAAAATTATTCAGGAGTTCCTGTCCAAGGTGAAACAAATGCCCTTTACTGAAATGTCAGAAGAAAACATCACAATAAAGTTAAAACAGCTAAAAGCTGAAGTAATAGCAAAGAATAATAGCTTTGTAAATGAAATCATTTCACGAATAAAAGTTACTACGTGA,dna,MSH2,GCF_000001405.26,P43246,Protein coding +9,urn:mavedb:00000061-i-1,TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAAGAACAGTGGTCAATGTGCGAAATGGAATGAGCTTGCATGACTGCCTTATGAAAGCACTCAAGGTGAGGGGC,dna,RAF,GCF_000001405.26,P04049,Protein coding +10,urn:mavedb:00000083-b-1,AGTTGAAGAAGGGAGCTCCAGCACAGTGAAATGGACAGAAGGGCAGAGCAA,dna,Minigene exon - SRSF1 (ASF/SF2) binding site,GCF_000001405.13,,Other noncoding +11,urn:mavedb:00000094-a-5,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +12,urn:mavedb:00000043-a-2,ACCGAGACCGCCTGGATCTCCTTGGTGACCGCTCTGCATCTAGTGCTGGGCCTCAACGCCGTCCTGGGCCTGCTGCTGCTGAGGTGGCAGTTT,dna,S505N MPL,GCF_000001405.10,P40238,Protein coding +13,urn:mavedb:00000055-0-1,ATGACGGCCAGCGCACAGCCGCGCGGGCGGCGGCCAGGAGTCGGAGTCGGAGTCGTGGTGACCAGCTGCAAGCATCCGCGTTGCGTCCTCCTGGGGAAGAGGAAAGGCTCGGTTGGAGCTGGCAGTTTCCAACTCCCTGGAGGTCATCTGGAGTTCGGTGAAACCTGGGAAGAATGTGCTCAAAGGGAAACCTGGGAAGAAGCAGCTCTTCACCTGAAAAATGTTCACTTTGCCTCAGTTGTGAATTCTTTCATTGAGAAGGAGAATTACCATTATGTTACTATATTAATGAAAGGAGAAGTGGATGTGACTCATGATTCAGAACCAAAGAATGTAGAGCCTGAAAAAAATGAAAGTTGGGAGTGGGTTCCTTGGGAAGAACTACCTCCCCTGGACCAGCTTTTCTGGGGACTGCGTTGTTTAAAAGAACAAGGCTATGATCCATTTAAAGAAGATCTGAACCATCTGGTGGGATACAAAGGAAATCATCTCTAG,dna,NUDT15,GCF_000001405.26,Q9NV35,Protein coding +14,urn:mavedb:00000104-a-2,CGGTGGCCGGTGCGGCGTGTTCGGTGGCGGCTCTGGCCGCTCAGGCGCCTGCGGCTGGGTGAGCGCACGCGAGGCGGCGAGGCGGCAGCGTGTTTCTAGGTCGTGGCGTCGGGCTTCCGGAGCTTTGGCGGCAGCTAGGGGAGGATGGCGGAGTCTTCGGATAAGCTCTATCGAGTCGAGTACGCCAAGAGCGGGCGCGCCTCTTGCAAGAAATGCAGCGAGAGCATCCCCAAGGACTCGCTCCGGATGGCCATCATGGTGCAGTCGCCCATGTTTGATGGAAAAGTCCCACACTGGTACCACTTCTCCTGCTTCTGGAAGGTGGGCCACTCCATCCGGCACCCTGACGTTGAGGTGGATGGGTTCTCTGAGCTTCGGTGGGATGACCAGCAGAAAGTCAAGAAGACAGCGGAAGCTGGAGGAGTGACAGGCAAAGGCCAGGATGGAATTGGTAGCAAGGCAGAGAAGACTCTGGGTGACTTTGCAGCAGAGTATGCCAAGTCCAACAGAAGTACGTGCAAGGGGTGTATGGAGAAGATAGAAAAGGGCCAGGTGCGCCTGTCCAAGAAGATGGTGGACCCGGAGAAGCCACAGCTAGGCATGATTGACCGCTGGTACCATCCAGGCTGCTTTGTCAAGAACAGGGAGGAGCTGGGTTTCCGGCCCGAGTACAGTGCGAGTCAGCTCAAGGGCTTCAGCCTCCTTGCTACAGAGGATAAAGAAGCCCTGAAGAAGCAGCTCCCAGGAGTCAAGAGTGAAGGAAAGAGAAAAGGCGATGAGGTGGATGGAGTGGATGAAGTGGCGAAGAAGAAATCTAAAAAAGAAAAAGACAAGGATAGTAAGCTTGAAAAAGCCCTAAAGGCTCAGAACGACCTGATCTGGAACATCAAGGACGAGCTAAAGAAAGTGTGTTCAACTAATGACCTGAAGGAGCTACTCATCTTCAACAAGCAGCAAGTGCCTTCTGGGGAGTCGGCGATCTTGGACCGAGTAGCTGATGGCATGGTGTTCGGTGCCCTCCTTCCCTGCGAGGAATGCTCGGGTCAGCTGGTCTTCAAGAGCGATGCCTATTACTGCACTGGGGACGTCACTGCCTGGACCAAGTGTATGGTCAAGACACAGACACCCAACCGGAAGGAGTGGGTAACCCCAAAGGAATTCCGAGAAATCTCTTACCTCAAGAAATTGAAGGTTAAAAAACAGGACCGTATATTCCCCCCAGAAACCAGCGCCTCCGTGGCGGCCACGCCTCCGCCCTCCACAGCCTCGGCTCCTGCTGCTGTGAACTCCTCTGCTTCAGCAGATAAGCCATTATCCAACATGAAGATCCTGACTCTCGGGAAGCTGTCCCGGAACAAGGATGAAGTGAAGGCCATGATTGAGAAACTCGGGGGGAAGTTGACGGGGACGGCCAACAAGGCTTCCCTGTGCATCAGCACCAAAAAGGAGGTGGAAAAGATGAATAAGAAGATGGAGGAAGTAAAGGAAGCCAACATCCGAGTTGTGTCTGAGGACTTCCTCCAGGACGTCTCCGCCTCCACCAAGAGCCTTCAGGAGTTGTTCTTAGCGCACATCTTGTCCCCTTGGGGGGCAGAGGTGAAGGCAGAGCCTGTTGAAGTTGTGGCCCCAAGAGGGAAGTCAGGGGCTGCGCTCTCCAAAAAAAGCAAGGGCCAGGTCAAGGAGGAAGGTATCAACAAATCTGAAAAGAGAATGAAATTAACTCTTAAAGGAGGAGCAGCTGTGGATCCTGATTCTGGACTGGAACACTCTGCGCATGTCCTGGAGAAAGGTGGGAAGGTCTTCAGTGCCACCCTTGGCCTGGTGGACATCGTTAAAGGAACCAACTCCTACTACAAGCTGCAGCTTCTGGAGGACGACAAGGAAAACAGGTATTGGATATTCAGGTCCTGGGGCCGTGTGGGTACGGTGATCGGTAGCAACAAACTGGAACAGATGCCGTCCAAGGAGGATGCCATTGAGCACTTCATGAAATTATATGAAGAAAAAACCGGGAACGCTTGGCACTCCAAAAATTTCACGAAGTATCCCAAAAAGTTCTACCCCCTGGAGATTGACTATGGCCAGGATGAAGAGGCAGTGAAGAAGCTGACAGTAAATCCTGGCACCAAGTCCAAGCTCCCCAAGCCAGTTCAGGACCTCATCAAGATGATCTTTGATGTGGAAAGTATGAAGAAAGCCATGGTGGAGTATGAGATCGACCTTCAGAAGATGCCCTTGGGGAAGCTGAGCAAAAGGCAGATCCAGGCCGCATACTCCATCCTCAGTGAGGTCCAGCAGGCGGTGTCTCAGGGCAGCAGCGACTCTCAGATCCTGGATCTCTCAAATCGCTTTTACACCCTGATCCCCCACGACTTTGGGATGAAGAAGCCTCCGCTCCTGAACAATGCAGACAGTGTGCAGGCCAAGGTGGAAATGCTTGACAACCTGCTGGACATCGAGGTGGCCTACAGTCTGCTCAGGGGAGGGTCTGATGATAGCAGCAAGGATCCCATCGATGTCAACTATGAGAAGCTCAAAACTGACATTAAGGTGGTTGACAGAGATTCTGAAGAAGCCGAGATCATCAGGAAGTATGTTAAGAACACTCATGCAACCACACACAATGCGTATGACTTGGAAGTCATCGATATCTTTAAGATAGAGCGTGAAGGCGAATGCCAGCGTTACAAGCCCTTTAAGCAGCTTCATAACCGAAGATTGCTGTGGCACGGGTCCAGGACCACCAACTTTGCTGGGATCCTGTCCCAGGGTCTTCGGATAGCCCCGCCTGAAGCGCCCGTGACAGGCTACATGTTTGGTAAAGGGATCTATTTCGCTGACATGGTCTCCAAGAGTGCCAACTACTGCCATACGTCTCAGGGAGACCCAATAGGCTTAATCCTGTTGGGAGAAGTTGCCCTTGGAAACATGTATGAACTGAAGCACGCTTCACATATCAGCAAGTTACCCAAGGGCAAGCACAGTGTCAAAGGTTTGGGCAAAACTACCCCTGATCCTTCAGCTAACATTAGTCTGGATGGTGTAGACGTTCCTCTTGGGACCGGGATTTCATCTGGTGTGAATGACACCTCTCTACTATATAACGAGTACATTGTCTATGATATTGCTCAGGTAAATCTGAAGTATCTGCTGAAACTGAAATTCAATTTTAAGACCTCCCTGTGGTAATTGGGAGAGGTAGCCGAGTCACACCCGGTGGCTCTGGTATGAATTCACCCGAAGCGCTTCTGCACCAACTCACCTGGCCGCTAAGTTGCTGATGGGTAGTACCTGTACTAAACCACCTCAGAAAGGATTTTACAGAAACGTGTTAAAGGTTTTCTCTAACTTCTCAAGTCCCTTGTTTTGTGTTGTGTCTGTGGGGAGGGGTTGTTTTGGGGTTGTTTTTGTTTTTTCTTGCCAGGTAGATAAAACTGACATAGAGAAAAGGCTGGAGAGAGATTCTGTTGCATAGACTAGTCCTATGGAAAAAACCAAGCTTCGTTAGAATGTCTGCCTTACTGGTTTCCCCAGGGAAGGAAAAATACACTTCCACCCTTTTTTCTAAGTGTTCGTCTTTAGTTTTGATTTTGGAAAGATGTTAAGCATTTATTTTTAGTTAAAAATAAAAACTAATTTCATACTATTTAGATTTTCTTTTTTATCTTGCACTTATTGTCCCCTTTTTAGTTTTTTTTGTTTGCCTCTTGTGGTGAGGGGTGTGGGAAGACCAAAGGAAGGAACGCTAACAATTTCTCATACTTAGAAACAAAAAGAGCTTTCCTTCTCCAGGAATACTGAACATGGGAGCTCTTGAAATATGTAGTATTAAAAGTTGCATTTGAAATTCTTGACTTTCTTATGGGCACTTTTGTCTTCCAAATTAAAACTCTACCACAAATATACTTACCCAAGGGCTAATAGTAATACTCGATTAAAAATGCAGATGCCTTCTCTA,dna,PARP1,GCF_000001405.26,,Protein coding +15,urn:mavedb:00000005-a-6,ATGCCTTCTGAGACCCCCCAGGCAGAAGTGGGGCCCACAGGCTGCCCCCACCGCTCAGGGCCACACTCGGCGAAGGGGAGCCTGGAGAAGGGGTCCCCAGAGGATAAGGAAGCCAAGGAGCCCCTGTGGATCCGGCCCGATGCTCCGAGCAGGTGCACCTGGCAGCTGGGCCGGCCTGCCTCCGAGTCCCCACATCACCACACTGCCCCGGCAAAATCTCCAAAAATCTTGCCAGATATTCTGAAGAAAATCGGGGACACCCCTATGGTCAGAATCAACAAGATTGGGAAGAAGTTCGGCCTGAAGTGTGAGCTCTTGGCCAAGTGTGAGTTCTTCAACGCGGGCGGGAGCGTGAAGGACCGCATCAGCCTGCGGATGATTGAGGATGCTGAGCGCGACGGGACGCTGAAGCCCGGGGACACGATTATCGAGCCGACATCCGGGAACACCGGGATCGGGCTGGCCCTGGCTGCGGCAGTGAGGGGCTATCGCTGCATCATCGTGATGCCAGAGAAGATGAGCTCCGAGAAGGTGGACGTGCTGCGGGCACTGGGGGCTGAGATTGTGAGGACGCCCACCAATGCCAGGTTCGACTCCCCGGAGTCACACGTGGGGGTGGCCTGGCGGCTGAAGAACGAAATCCCCAATTCTCACATCCTAGACCAGTACCGCAACGCCAGCAACCCCCTGGCTCACTACGACACCACCGCTGATGAGATCCTGCAGCAGTGTGATGGGAAGCTGGACATGCTGGTGGCTTCAGTGGGCACGGGCGGCACCATCACGGGCATTGCCAGGAAGCTGAAGGAGAAGTGTCCTGGATGCAGGATCATTGGGGTGGATCCCGAAGGGTCCATCCTCGCAGAGCCGGAGGAGCTGAACCAGACGGAGCAGACAACCTACGAGGTGGAAGGGATCGGCTACGACTTCATCCCCACGGTGCTGGACAGGACGGTGGTGGACAAGTGGTTCAAGAGCAACGATGAGGAGGCGTTCACCTTTGCCCGCATGCTGATCGCGCAAGAGGGGCTGCTGTGCGGTGGCAGTGCTGGCAGCACGGTGGCGGTGGCCGTGAAGGCCGCGCAGGAGCTGCAGGAGGGCCAGCGCTGCGTGGTCATTCTGCCCGACTCAGTGCGGAACTACATGACCAAGTTCCTGAGCGACAGGTGGATGCTGCAGAAGGGCTTTCTGAAGGAGGAGGACCTCACGGAGAAGAAGCCCTGGTGGTGGCACCTCCGTGTTCAGGAGCTGGGCCTGTCAGCCCCGCTGACCGTGCTCCCGACCATCACCTGTGGGCACACCATCGAGATCCTCCGGGAGAAGGGCTTCGACCAGGCGCCCGTGGTGGATGAGGCGGGGGTAATCCTGGGAATGGTGACGCTTGGGAACATGCTCTCGTCCCTGCTTGCCGGGAAGGTGCAGCCGTCAGACCAAGTTGGCAAAGTCATCTACAAGCAGTTCAAACAGATCCGCCTCACGGACACGCTGGGCAGGCTCTCGCACATCCTGGAGATGGACCACTTCGCCCTGGTGGTGCACGAGCAGATCCAGTACCACAGCACCGGGAAGTCCAGTCAGCGGCAGATGGTGTTCGGGGTGGTCACCGCCATTGACTTGCTGAACTTCGTGGCCGCCCAGGAGCGGGACCAGAAGTGA,dna,CBS,GCF_000001405.26,P35520,Protein coding +16,urn:mavedb:00000083-h-1,AGTTCGCGCCGGGAGCTCCAGCACAGTGAAATGGACAGAAGGGCAGAGCAA,dna,Minigene exon - CG-containing enhancer,GCF_000001405.13,,Other noncoding +17,urn:mavedb:00000098-a-1,LFRVIRLARIGR,protein,SCN5A,GCF_000001405.26,Q14524,Protein coding +18,urn:mavedb:00000108-a-2,ATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGCATGAAGATGGCCCTGAGGATGACCCACAGTTGGTAGGCATCACTGCTCGTAACATTCCACGAGGGCCCCAGTTGGCTGCCCAGAACTTGGGCATCAGCCTGGCCAACTTGTTGCTGAGCAAAGGAGCCAAAAACATCCTGGATGTTGCACGGCAGCTTAACGATGCCCATTAA,dna,HMBS,GCF_000001405.26,P08397,Protein coding +19,urn:mavedb:00000001-a-4,ATGTCGGGGATCGCCCTCAGCAGACTCGCCCAGGAGAGGAAAGCATGGAGGAAAGACCACCCATTTGGTTTCGTGGCTGTCCCAACAAAAAATCCCGATGGCACGATGAACCTCATGAACTGGGAGTGCGCCATTCCAGGAAAGAAAGGGACTCCGTGGGAAGGAGGCTTGTTTAAACTACGGATGCTTTTCAAAGATGATTATCCATCTTCGCCACCAAAATGTAAATTCGAACCACCATTATTTCACCCGAATGTGTACCCTTCGGGGACAGTGTGCCTGTCCATCTTAGAGGAGGACAAGGACTGGAGGCCAGCCATCACAATCAAACAGATCCTATTAGGAATACAGGAACTTCTAAATGAACCAAATATCCAAGACCCAGCTCAAGCAGAGGCCTACACGATTTACTGCCAAAACAGAGTGGAGTACGAGAAAAGGGTCCGAGCACAAGCCAAGAAGTTTGCGCCCTCATAA,dna,UBE2I,GCF_000001405.26,P63279,Protein coding +20,urn:mavedb:00000094-a-6,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +21,urn:mavedb:00000078-a-1,MGSTWGSPGWVRLALCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWGRGFGLVEHVLGQDSILNQSNSIFGCIFYTLQLLLGCLRTRWASVLMLLSSLVSLAGSVYLAWILFFVLYDFCIVCITTYAINVSLMWLSFRKVQEPQGKAKRH,protein,VKOR,GCF_000001405.26,,Protein coding +22,urn:mavedb:00000103-c-1,MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS,protein,MAPK1,GCF_000001405.26,,Protein coding +23,urn:mavedb:00000043-a-1,ACCGAGACCGCCTGGATCTCCTTGGTGACCGCTCTGCATCTAGTGCTGGGCCTCAGCGCCGTCCTGGGCCTGCTGCTGCTGAGGTGGCAGTTT,dna,MPL,GCF_000001405.10,P40238,Protein coding +24,urn:mavedb:00000061-d-1,TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAAGAACAGTGGTCAATGTGCGAAATGGAATGAGCTTGCATGACTGCCTTATGAAAGCACTCAAGGTGAGGGGC,dna,RAF,GCF_000001405.26,P04049,Protein coding +25,urn:mavedb:00000046-a-1,GACCACATTCCTTGGATTACAGCTGTACTTCCAACAGTTATTATATGTGTGATGGTTTTCTGTCTAATTCTATGGAAATGG,dna,CD86,GCF_000001405.10,P42081,Protein coding +26,urn:mavedb:00000081-a-1,MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKEFVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHSRETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVTFECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRGNETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY,protein,BRCA1,GCF_000001405.13,P38398,Protein coding +27,urn:mavedb:00000097-r-1,TTTCTTTCAGCATGATTTTGAAGTCAGAGGAGATGTGGTCAATGGAAGAAACCACCAAGGTCCAAAGCGAGCAAGAGAATCCCAGGACAGAAAGGTAAAGCTCC,dna,BRCA1 Exon 19,GCF_000001405.13,,Protein coding +28,urn:mavedb:00000067-a-1,ATGAAGCATTACGAGGTGGAGATTCTGGACGCAAAGACAAGGGAGAAGCTGTGTTTCTTGGACAAGGTGGAGCCCCACGCCACCATTGCGGAGATCAAGAACCTCTTCACTAAGACCCATCCGCAGTGGTACCCCGCCCGCCAGTCCCTCCGCCTGGACCCCAAGGGCAAGTCCCTGAAGGATGAGGATGTTCTGCAGAAGCTGCCCGTGGGCACCACGGCCACACTGTACTTCCGGGACCTGGGGGCCCAGATCAGCTGGGTGACGGTCTTCCTAACAGAGTACGCGGGGCCCCTTTTCATCTACCTGCTCTTCTACTTCCGAGTGCCCTTCATCTATGGCCACAAATATGACTTTACGTCCAGTCGGCATACAGTGGTGCACCTCGCCTGCATCTGTCACTCATTCCACTACATCAAGCGCCTGCTGGAGACGCTCTTCGTGCACCGCTTCTCCCATGGCACTATGCCTTTGCGCAACATCTTCAAGAACTGCACCTACTACTGGGGCTTCGCCGCGTGGATGGCCTATTACATCAATCACCCTCTCTACACTCCCCCTACCTACGGAGCTCAGCAGGTGAAACTGGCGCTCGCCATCTTTGTGATCTGCCAGCTCGGCAACTTCTCCATCCACATGGCCCTGCGGGACCTGCGGCCCGCTGGGTCCAAGACGCGGAAGATCCCATACCCCACCAAGAACCCCTTCACGTGGCTCTTCCTGCTGGTGTCCTGCCCCAACTACACCTACGAGGTGGGGTCCTGGATCGGTTTCGCCATCATGACGCAGTGTCTCCCAGTGGCCCTGTTCTCCCTGGTGGGCTTCACCCAGATGACCATCTGGGCCAAGGGCAAGCACCGCAGCTACCTGAAGGAGTTCCGGGACTACCCGCCCCTGCGCATGCCCATCATCCCCTTCCTGCTCTGA,dna,TECR,GCF_000001405.26,Q9NZ01,Protein coding +29,urn:mavedb:00000001-c-2,ATGGCTGATCAGCTGACCGAAGAACAGATTGCTGAATTCAAGGAAGCCTTCTCCCTATTTGATAAAGATGGCGATGGCACCATCACAACAAAGGAACTTGGAACTGTCATGAGGTCACTGGGTCAGAACCCAACAGAAGCTGAATTGCAGGATATGATCAATGAAGTGGATGCTGATGGTAATGGCACCATTGACTTCCCCGAATTTTTGACTATGATGGCTAGAAAAATGAAAGATACAGATAGTGAAGAAGAAATCCGTGAGGCATTCCGAGTCTTTGACAAGGATGGCAATGGTTATATCAGTGCAGCAGAACTACGTCACGTCATGACAAACTTAGGAGAAAAACTAACAGATGAAGAAGTAGATGAAATGATCAGAGAAGCAGATATTGATGGAGACGGACAAGTCAACTATGAAGAATTCGTACAGATGATGACTGCAAAATGA,dna,CALM1,GCF_000001405.26,P0DP23,Protein coding +30,urn:mavedb:00000049-a-7,ATGGTGAACGAAGCCAGAGGAAACAGCAGCCTCAACCCCTGCTTGGAGGGCAGTGCCAGCAGTGGCAGTGAGAGCTCCAAAGATAGTTCGAGATGTTCCACCCCGGGCCTGGACCCCGAGCGGCATGAGAGACTCCGGGAGAAGATGAGGCGGCGATTGGAATCTGGTGACAAGTGGTTCTCCCTGGAATTCTTCCCTCCTCGAACTGCTGAGGGAGCTGTCAATCTCATCTCAAGGTTTGACCGGATGGCAGCAGGTGGCCCCCTCTACATAGACGTGACCTGGCACCCAGCAGGTGACCCTGGCTCAGACAAGGAGACCTCCTCCATGATGATCGCCAGCACCGCCGTGAACTACTGTGGCCTGGAGACCATCCTGCACATGACCTGCTGCCGTCAGCGCCTGGAGGAGATCACGGGCCATCTGCACAAAGCTAAGCAGCTGGGCCTGAAGAACATCATGGCGCTGCGGGGAGACCCAATAGGTGACCAGTGGGAAGAGGAGGAGGGAGGCTTCAACTACGCAGTGGACCTGGTGAAGCACATCCGAAGTGAGTTTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCGAAGCAGGGAGCTTTGAGGCTGACCTGAAGCACTTGAAGGAGAAGGTGTCTGCGGGAGCCGATTTCATCATCACGCAGCTTTTCTTTGAGGCTGACACATTCTTCCGCTTTGTGAAGGCATGCACCGACATGGGCATCACTTGCCCCATCGTCCCCGGGATCTTTCCCATCCAGGGCTACCACTCCCTTCGGCAGCTTGTGAAGCTGTCCAAGCTGGAGGTGCCACAGGAGATCAAGGACGTGATTGAGCCAATCAAAGACAACGATGCTGCCATCCGCAACTATGGCATCGAGCTGGCCGTGAGCCTGTGCCAGGAGCTTCTGGCCAGTGGCTTGGTGCCAGGCCTCCACTTCTACACCCTCAACCGCGAGATGGCTACCACAGAGGTGCTGAAGCGCCTGGGGATGTGGACTGAGGACCCCAGGCGTCCCCTACCCTGGGCTCTCAGCGCCCACCCCAAGCGCCGAGAGGAAGATGTACGTCCCATCTTCTGGGCCTCCAGACCAAAGAGTTACATCTACCGTACCCAGGAGTGGGACGAGTTCCCTAACGGCCGCTGGGGCAATTCCTCTTCCCCTGCCTTTGGGGAGCTGAAGGACTACTACCTCTTCTACCTGAAGAGCAAGTCCCCCAAGGAGGAGCTGCTGAAGATGTGGGGGGAGGAGCTGACCAGTGAAGAAAGTGTCTTTGAAGTCTTCGTTCTTTACCTCTCGGGAGAACCAAACCGGAATGGTCACAAAGTGACTTGCCTGCCCTGGAACGATGAGCCCCTGGCGGCTGAGACCAGCCTGCTGAAGGAGGAGCTGCTGCGGGTGAACCGCCAGGGCATCCTCACCATCAACTCACAGCCCAACATCAACGGGAAGCCGTCCTCCGACCCCATCGTGGGCTGGGGCCCCAGCGGGGGCTATGTCTTCCAGAAGGCCTACTTAGAGTTTTTCACTTCCCGCGAGACAGCGGAAGCACTTCTGCAAGTGCTGAAGAAGTACGAGCTCCGGGTTAATTACCACCTTGTCAATGTGAAGGGTGAAAACATCACCAATGCCCCTGAACTGCAGCCGAATGCTGTCACTTGGGGCATCTTCCCTGGGCGAGAGATCATCCAGCCCACCGTAGTGGATCCCGTCAGCTTCATGTTCTGGAAGGACGAGGCCTTTGCCCTGTGGATTGAGCGGTGGGGAAAGCTGTATGAGGAGGAGTCCCCGTCCCGCACCATCATCCAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAATGACTTCCCACTGGACAACTGCCTCTGGCAGGTGGTGGAAGACACATTGGAGCTTCTCAACAGGCCCACCCAGAATGCGAGAGAAACGGAGGCTCCATGA,dna,MTHFR,GCF_000001405.26,P42898,Protein coding +31,urn:mavedb:00000060-a-2,ATGTCTGAATATATTCGGGTAACCGAAGATGAGAACGATGAGCCCATTGAAATACCATCGGAAGACGATGGGACGGTGCTGCTCTCCACGGTTACAGCCCAGTTTCCAGGGGCGTGTGGGCTTCGCTACAGGAATCCAGTGTCTCAGTGTATGAGAGGTGTCCGGCTGGTAGAAGGAATTCTGCATGCCCCAGATGCTGGCTGGGGAAATCTGGTGTATGTTGTCAACTATCCAAAAGATAACAAAAGAAAAATGGATGAGACAGATGCTTCATCAGCAGTGAAAGTGAAAAGAGCAGTCCAGAAAACATCCGATTTAATAGTGTTGGGTCTCCCATGGAAAACAACCGAACAGGACCTGAAAGAGTATTTTAGTACCTTTGGAGAAGTTCTTATGGTGCAGGTCAAGAAAGATCTTAAGACTGGTCATTCAAAGGGGTTTGGCTTTGTTCGTTTTACGGAATATGAAACACAAGTGAAAGTAATGTCACAGCGACATATGATAGATGGACGATGGTGTGACTGCAAACTTCCTAATTCTAAGCAAAGCCAAGATGAGCCTTTGAGAAGCAGAAAAGTGTTTGTGGGGCGCTGTACAGAGGACATGACTGAGGATGAGCTGCGGGAGTTCTTCTCTCAGTACGGGGATGTGATGGATGTCTTCATCCCCAAGCCATTCAGGGCCTTTGCCTTTGTTACATTTGCAGATGATCAGATTGCGCAGTCTCTTTGTGGAGAGGACTTGATCATTAAAGGAATCAGCGTTCATATATCCAATGCCGAACCTAAGCACAATAGCAATAGACAGTTAGAAAGAAGTGGAAGATTTGGTGGTAATCCAGGTGGCTTTGGGAATCAGGGTGGATTTGGTAATAGCAGAGGGGGTGGAGCTGGTTTGGGAAACAATCAAGGTAGTAATATGGGTGGTGGGATGAACTTTGGTGCGTTCAGCATTAATCCAGCCATGATGGCTGCCGCCCAGGCAGCACTACAGAGCAGTTGGGGTATGATGGGCATGTTAGCCAGCCAGCAGAACCAGTCAGGCCCATCGGGTAATAACCAAAACCAAGGCAACATGCAGAGGGAGCCAAACCAGGCCTTCGGTTCTGGAAATAACTCTTATAGTGGCTCTAATTCTGGTGCAGCAATTGGTTGGGGATCAGCATCCAATGCAGGGTCGGGCAGTGGTTTTAATGGAGGCTTTGGCTCAAGCATGGATTCTAAGTCTTCTGGCTGGGGAATG,dna,TARDBP,GCF_000001405.13,Q13148,Protein coding +32,urn:mavedb:00000058-a-1,GATGCAGAATTCCGACATGACTCAGGATATGAAGTTCATCATCAAAAATTGGTGTTCTTTGCAGAAGATGTGGGTTCAAACAAAGGTGCAATCATTGGACTCATGGTGGGCGGTGTTGTCATAGCG,dna,Aβ42,GCF_000001405.26,P05067,Protein coding +33,urn:mavedb:00000045-k-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +34,urn:mavedb:00000094-a-14,MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS,protein,KCNQ1,GCF_000001405.26,,Protein coding +35,urn:mavedb:00000069-a-2,MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNPGFQNTDDVQTSF,protein,ACE2,GCF_000001405.26,Q9BYF1,Protein coding +36,urn:mavedb:00000106-b-1,MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL,protein,AID,GCF_000001405.26,,Protein coding +37,urn:mavedb:00000046-a-2,GACCACATTCCTTGGATTACAGCTGTACTTCCAACAGTTATTATATGTGTGATGGTTTTCTGTCTAATTCTATGGAAATGG,dna,CD86,GCF_000001405.10,P42081,Protein coding +38,urn:mavedb:00000069-a-1,MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNPGFQNTDDVQTSF,protein,ACE2,GCF_000001405.26,,Protein coding +39,urn:mavedb:00000034-b-1,TGAGATATGGCTTCATTTTCTGTAATAAACACTAAGATCAAAACATGACCCAAGTTAAATTTCCTTGCAGGGTTCCCAGCAGGGGCTTCCCTTTTGTCTGTGATTTCCTCTCACCCACCAGAACCAGGCCAAATATGCGCATGTGCCACTAACACTAAGCAGCACTTCCTTAATCACTCATTTCCAACAATTTATGGATCATCAGTGGCAAAAAACGAGCAAAAATAATGAAAGAATGCAATGAAAGCTCGTGGAGACAGAGGCTGGACTTCCTACTCACTCTGTGTCTCTTTAAGATGGAGGCCTGATACAAATTAGCCACTGGGGGGAAAAAGTCATCTGGTCATAAAATACAGTACAAGGTCACTTTTATGTAAGTTTGCCAAAAGGGACATAAACCAGGACAATTTCAAACTGTGACACAGGATAGAAACATATTAAAAAAATCTTTGTTCCTCCTCTATTGTGCTGTCATGTTGCTCAGCA,dna,ZRS enhancer,GCF_000001405.26,,Regulatory +40,urn:mavedb:00000049-a-8,ATGGTGAACGAAGCCAGAGGAAACAGCAGCCTCAACCCCTGCTTGGAGGGCAGTGCCAGCAGTGGCAGTGAGAGCTCCAAAGATAGTTCGAGATGTTCCACCCCGGGCCTGGACCCCGAGCGGCATGAGAGACTCCGGGAGAAGATGAGGCGGCGATTGGAATCTGGTGACAAGTGGTTCTCCCTGGAATTCTTCCCTCCTCGAACTGCTGAGGGAGCTGTCAATCTCATCTCAAGGTTTGACCGGATGGCAGCAGGTGGCCCCCTCTACATAGACGTGACCTGGCACCCAGCAGGTGACCCTGGCTCAGACAAGGAGACCTCCTCCATGATGATCGCCAGCACCGCCGTGAACTACTGTGGCCTGGAGACCATCCTGCACATGACCTGCTGCCGTCAGCGCCTGGAGGAGATCACGGGCCATCTGCACAAAGCTAAGCAGCTGGGCCTGAAGAACATCATGGCGCTGCGGGGAGACCCAATAGGTGACCAGTGGGAAGAGGAGGAGGGAGGCTTCAACTACGCAGTGGACCTGGTGAAGCACATCCGAAGTGAGTTTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCGAAGCAGGGAGCTTTGAGGCTGACCTGAAGCACTTGAAGGAGAAGGTGTCTGCGGGAGCCGATTTCATCATCACGCAGCTTTTCTTTGAGGCTGACACATTCTTCCGCTTTGTGAAGGCATGCACCGACATGGGCATCACTTGCCCCATCGTCCCCGGGATCTTTCCCATCCAGGGCTACCACTCCCTTCGGCAGCTTGTGAAGCTGTCCAAGCTGGAGGTGCCACAGGAGATCAAGGACGTGATTGAGCCAATCAAAGACAACGATGCTGCCATCCGCAACTATGGCATCGAGCTGGCCGTGAGCCTGTGCCAGGAGCTTCTGGCCAGTGGCTTGGTGCCAGGCCTCCACTTCTACACCCTCAACCGCGAGATGGCTACCACAGAGGTGCTGAAGCGCCTGGGGATGTGGACTGAGGACCCCAGGCGTCCCCTACCCTGGGCTCTCAGCGCCCACCCCAAGCGCCGAGAGGAAGATGTACGTCCCATCTTCTGGGCCTCCAGACCAAAGAGTTACATCTACCGTACCCAGGAGTGGGACGAGTTCCCTAACGGCCGCTGGGGCAATTCCTCTTCCCCTGCCTTTGGGGAGCTGAAGGACTACTACCTCTTCTACCTGAAGAGCAAGTCCCCCAAGGAGGAGCTGCTGAAGATGTGGGGGGAGGAGCTGACCAGTGAAGAAAGTGTCTTTGAAGTCTTCGTTCTTTACCTCTCGGGAGAACCAAACCGGAATGGTCACAAAGTGACTTGCCTGCCCTGGAACGATGAGCCCCTGGCGGCTGAGACCAGCCTGCTGAAGGAGGAGCTGCTGCGGGTGAACCGCCAGGGCATCCTCACCATCAACTCACAGCCCAACATCAACGGGAAGCCGTCCTCCGACCCCATCGTGGGCTGGGGCCCCAGCGGGGGCTATGTCTTCCAGAAGGCCTACTTAGAGTTTTTCACTTCCCGCGAGACAGCGGAAGCACTTCTGCAAGTGCTGAAGAAGTACGAGCTCCGGGTTAATTACCACCTTGTCAATGTGAAGGGTGAAAACATCACCAATGCCCCTGAACTGCAGCCGAATGCTGTCACTTGGGGCATCTTCCCTGGGCGAGAGATCATCCAGCCCACCGTAGTGGATCCCGTCAGCTTCATGTTCTGGAAGGACGAGGCCTTTGCCCTGTGGATTGAGCGGTGGGGAAAGCTGTATGAGGAGGAGTCCCCGTCCCGCACCATCATCCAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAATGACTTCCCACTGGACAACTGCCTCTGGCAGGTGGTGGAAGACACATTGGAGCTTCTCAACAGGCCCACCCAGAATGCGAGAGAAACGGAGGCTCCATGA,dna,MTHFR,GCF_000001405.26,P42898,Protein coding +41,urn:mavedb:00000047-c-1,GATTATCAAGTGTCAAGTCCAATCTATGACATCAATTATTATACATCGGAGCCCTGCCAAAAAATCAATGTGAAGCAAATCGCAGCCCGCCTCCTGCCTCCGCTCTACTCACTGGTGTTCATCTTTGGTTTTGTGGGCAACATGCTGGTCATCCTCATCCTGATAAACTGCAAAAGGCTGAAGAGCATGACTGACATCTACCTGCTCAACCTGGCCATCTCTGACCTGTTTTTCCTTCTTACTGTCCCCTTCTGGGCTCACTATGCTGCCGCCCAGTGGGACTTTGGAAATACAATGTGTCAACTCTTGACAGGGCTCTATTTTATAGGCTTCTTCTCTGGAATCTTCTTCATCATCCTCCTGACAATCGATAGGTACCTGGCTGTCGTCCATGCTGTGTTTGCTTTAAAAGCCAGGACGGTCACCTTTGGGGTGGTGACAAGTGTGATCACTTGGGTGGTGGCTGTGTTTGCGTCTCTCCCAGGAATCATCTTTACCAGATCTCAAAAAGAAGGTCTTCATTACACCTGCAGCTCTCATTTTCCATACAGTCAGTATCAATTCTGGAAGAATTTCCAGACATTAAAGATAGTCATCTTGGGGCTGGTCCTGCCGCTGCTTGTCATGGTCATCTGCTACTCGGGAATCCTAAAAACTCTGCTTCGGTGTCGAAATGAGAAGAAGAGGCACAGGGCTGTGAGGCTTATCTTCACCATCATGATTGTTTATTTTCTCTTCTGGGCTCCCTACAACATTGTCCTTCTCCTGAACACCTTCCAGGAATTCTTTGGCCTGAATAATTGCAGTAGCTCTAACAGGTTGGACCAAGCTATGCAGGTGACAGAGACTCTTGGGATGACGCACTGCTGCATCAACCCCATCATCTATGCCTTTGTCGGGGAGAAGTTCAGAAACTACCTCTTAGTCTTCTTCCAAAAGCACATTGCCAAACGCTTCTGCAAATGCTGTTCTATTTTCCAGCAAGAGGCTCCCGAGCGAGCAAGCTCAGTTTACACCCGATCCACTGGGGAGCAGGAAATATCTGTGGGCTTG,dna,CCR5,GCF_000001405.26,P51681,Protein coding +42,urn:mavedb:00000094-a-8,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +43,urn:mavedb:00000041-b-1,GGTAGCAACAAGAGCAAGCCCAAGGATGCCAGCCAGCGGCGCCGCAGCCTGGAG,dna,Src SH4 domain,GCF_000001405.26,P12931,Protein coding +44,urn:mavedb:00000097-o-1,TGTAACCTGTCTTTTCTATGATCTCTTTAGGGGTGACCCAGTCTATTAAAGAAAGAAAAATGCTGAATGAGGTAAGTACTTGATGTTACAAACTAACCAGA,dna,BRCA1 Exon 18,GCF_000001405.13,,Protein coding +45,urn:mavedb:00000045-a-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +46,urn:mavedb:00000097-0-1,AAGTTCATTGGAACAGAAAGAAATGGATTTATCTGCTCTTCGCGTTGAAGAAGTACAAAATGTCATTAATGCTATGCAGAAAATCTTAGAGTGTCCCATCTGGTAAGTCAGCACAAGAGTGTATTAATTTGGGATTCCTATGATTATCTCCTATGCAAATGAACAGAATTGACCTTACATACTAGGGAAGAAAAGACATGTCTAGTAAGATTAGGCTATTGTAATTGCTGATTTTCTTAACTGAAGAACTTTAAAAATATAGAAAATGATTCCTTGTTCTCCATCCACTCTGCCTCTCCCACTCCTCTCCTTTTCAACACAAATCCTGTGGTCCGGGAAAGACAGGGACTCTGTCTTGATTGGTTCTGCACTGGGGCAGGAATCTAGTTTAGATTAACTGGCATTTTGGCTTTTCTTCCAGCTCTAAAACAAGCTCCATCACTTGAAATGGCAAAATAAAATCATGGATGAGGCCGAGGGCGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGTAGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACATGGTGAAACCCCCTCTCCACTAAAAATACAAAAATTAGCTGGGCGTAGTGGCATGTGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCAGGAGGCAGATGTTGCTGTGAGCCAATATGGCACCACTGAACTCCAGCGACAGAGCTAAACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAACATGGATGATCGGTGTCGTTGAGAGGATAGGTATTTGGAAGAACCTTTGTTTGAAACTGGCTCTGTACATACAATGAAATTACATACTTATTTACATACAATGAAATGCAGAGGTTTTTTTTTTATATAGGATCTCTGTCGAGAGGCTGGAGTGCAGTGGTGCTATCACAGCTCACTGCAGCCTCAACCTCGTCAGGCTCAAGCAATCCTCCCACCTCAGCCTCCAGAGTAGCAGGGACGATAGGTGTGCACCACCATGCCCAGCTAATTTTTGTATTTTTTTTTCTTTTTTTGAGATGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCAAACTCTGCCTCCCGGGTTCATGCCATTCTTCTGCCTGAGCCTCCTGAATAGCTGGGACTACAAGCACCCACTACCACGCCCGGCTAATTTTTTGTATTTTTTTTTCTTTTTTAGTAGAGGCGGGATTTCACCGTGTTAGCCAGGATAGTCTTGATCTCCTGACCTTGTGATCCACCCGCCTGGGCCTCCCAAAGTGCTAGGATTACAGGCATAAGCCACTGCGTCCAGCCATTCTTGTATTTTTCTGTTGTAGAGATAGGGTTTTGCTATGTTGGCCATGCTGGTCTCAAACTCCTGACCTCAAGTGATCTACCCTCCCTTGGCCTCTCAAGGTGCTGGGATTACAGGCCTGAGCCATTGCACCCAGCCATGGTCTAAAAATCTTGATTGAAATACCACCTTTTCATTTCCAGACACCCCTATTTAAAATTACCACACCCCCAGCACACACTTTATCTTCTATTCCTGCTGCTTCTCCATAACACTGATTACTAGCTGACATTCTATGTAATGTATCCATTTTTTATCTCTAGTCCCACAGAATGTAAACTCCAGGATGGGATTTTTGTTTTGTTTACATACATCTGTATGTTCAGTAGTTAGAACGGTACTTGGGACCTAGTTGCCACTCAATAAACATTTGTCAAATAAATAATAAACTAAACTAAATTAGTTCTTTAATTTTTTTAAATATGGTGATGGTTAGTAGTGAGTAACATTCAAAAAATAAGTTGAAAAGTTGTACCATTGCCTCTTACCCACAATAAAAAAGGGTAAATTCTTTTCTGCTTTATGAAAGTTGTTTTTCATATTTGAAGTCAAGTTAATCAGATTAAGGAAAATGTATGTTGTGTTTTCAGAGCGATACAAGATTTATAAATAACCATCCTCTCCCTTGCCCTTCAACATTATAGCTAAACAAAAATAAGAGGAAAACAGGATTCACAATTTATCAATTTATTGAAAATCAGAGCCAGAGAAGCAGGAAATGACATTGTAGGAAAAAACTGCTTTTGAAAAAGCACAAAACTTACTCATGACAATCAGTGATCAGGAAAATCCTCAATAGTGTGGCATTTGGATACATTTATGTTTCATTTCCATGGGAGAGAGTCATAAAAATAGGATGTTCTTTCTCATTCTGGCAAATTAAACCATCAATTAAAAACTCAGATACATAAAAATTAAAGATGTAAGAATGAAAATGCTAAATTGTTATTTTCAATCAACTATTATGTTTTCTAGCTTTTCATTGCTTTTTTCTGTTTCCTGTTAAGATTAATTTCTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGACTTTGGCTCTTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTACAACCTCCACCTCCCGGGTTCAAGCAATTCTGCTGCCTCAGCCTCCGGAGTACCTGGGATTGCAGGCATGTGCCATCACACCAGCTAATTTTGTATTTTTAGTAGAGACAGGGTTTCTCCATATTGGTCAGGTTGGTCTCGAACTCCTGACCTCAGGTGATCCTCCTGCCTTGGCCTCCGAAAGTGCTGGGATTACAGGCGTGAGCCACCGCTCCCAGACTTTTTGTTTTGTTTTGTTTTGTTTTTTTGAGACACGGTCTCGCTCTGCTGCCTAGGCTGGAGTGCAGTGGCACGATCTTGGCTCACTGCCAGCTCCGCCTCCCGGGTTCAGGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACTATGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAAGATGGTCTCGATCTCCTGACCTTGTGATCCACCCGCCTCAGCCTTCCAAAGTGCTGGGATTACAGTCCTGAGCCACTGCGCCCGGCCTGGACCTTTTTTTTTCGGGGTGGGGGGTTGGAGTCTGGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCCATCTTGGCTCACTGCAACCTCCGCCTGCCAGGTTCAAGTTCAAGCGCTTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTATAGGCGCACGCCACCGTGGCCGGCTAATTTTGTATTTTTAGTAGAGATAGGGTTTCATCACGTTGGTCAGGCTGGTCTTGAAGTCCTGATCTCGTGATCCACCCGCCTCGGCCTTCCAAAGTGCTGGCGTGAGCCACTGCGCCTGGCTTAAGATTAATTTTTGTTTGTTTTGTTTTTGAGACGGAGTCTCGCTCTTTCACCCAGGCCGGAGTGCAGTGGCGCCATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCGGCCCCCCAAGTAGCTGGGACTACAGGCGTCCACCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCCACTTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTTAAGATTAATTTTTATGGTGTTTTACATTCATTTGTATGGAAAGTTCTAGGATAGGGATCATATTTCACTTCCTTTTAATATAGTACAGTATAGCACAATTTGCAGTTATGTCTTAATATGTGATCAGGAATGATCATGACTGGAAACAGTGTTATTTGTGGTAGCTATAGGGTAGGTAAGGTTTTCAGCCTGTTTTAGGTTTCTTGAACTAAAATTCCTTCTGCTGTCTTCTAAGTCAATATTGGCAGCTATTTCTGACAATTGGTAGTTCTTTGTAACTTTTTACCTATGACTATAACATTTTTGACTTTCAGAAGAATTTGCTAAAATGTGTTCCCCGGTGGGTTGTTGTTTTTCAACCTAAACCTAGCTGCTTTTTCCAGTCACTTATCCGTATTGGAAGCTCAAAATGCAAATATACAGTAGGCCTAAAATATTGCCTGGTTTGAAAAGTGTTTAAAATATTTGAATCATTTTTATAGTAAACATTTACTCTCATCAGGACCTAGAAGGGGAACATTTTAATTTTTTTTCTTTTCCCTTTTCACAGTCTTCCTTCAACATTCATTACCTTTTTACATATCGGAGTTTTCATCTGTTCAAAGTTTGTGTTTACAGTGTGTTTATATAGTTTAGATTATAATTACCATACTGAAATATAATTGTTTCAGAATTGAGTCAGTGGTGAGAATGAAAGCCATCTGGTATGATAACTGAATCCAATTTTTCTTTTACGGAGAATTTCTTTGAAATGTAGCTTATCTCAGAAATAGGGATTTAGTAACCAATCAGAGTTTTCTTTGTCAAGGTTGTTTTTCTTTTTAAAGTCACATTTGGTCCCAGTAATAATACCAATGTTGGTACAAGTTATCTCAGGTTGTGAAGCATTTTTCCCAAGTCATCTCAGGTTGTGAAGCATTTTCCCAAGTAGCATTTAATTTTATTCTTGCAATAGCCCAAGGAGTCTGGCAGGGTGAATGGCAAGAGAAGGAAACAGGTTCAGGTAGAGTGGTTAGCCCAAGGTGGCTCTGCTTATATACACAACTGGTAGTAGAAACCCAGCCTCCTGACTTAGTTCATTGTTTTTCTTTTCACTGCCCTGTGCTATGTCAAAAACCCCATGATTACAAGAGTTGTATTACAACCCTTCACAATAAGGTTACTGTCCACAAGCTTTTCTTGTGATCCTTTTCTTTTTTTTTTTTCTTTTTTTGAGATGGATTCTCTGTCACCCAGGCTGGCCCGCCTTGGCCTCCCAAAATGCTGGGATTACAGCGTGAGCCACCGCACCTGGCCCTTGTGATCCTTTTCTAAAAAGTTAAATATTTAAGGAAAAAACCACATTCTTGTCACACTGCCAGGTTAGTCGTTCTTTGATATCTTGCCTGGACTTTATCCAAAAAATCCGTTTCAAAAATTCACATTTAGAGCTAAGTGTAGTGGCTCACGCCTGTAATCCCGGTCGAGGCAGATGGATCACTTGAGGTCAGGACTTCAAGACCAGCCTGGGCAATATGGTGAAACCCCTTCCCTACCAAAAATACAAAAAAATTAGCCGGGTGTGGCAGCACGCGCCTGTAGTCCCAGCTACTTGGAATGCTGAGGCACAAGAATCACTTCAATCCGAGAGGCAGAGGTTGCAGTGAGCCAAGACCACACCACTGCACTCCAGCCTGAGCAGCAGAGTGAGTGAGACTCCATCTCCAAAAAAAAAAAAAAAGGTTCACATTCAGAAGAAAGCTAAAGGCCGGGTATAGTAGCTCACACCTGTAATCCCAGCACTTTGGGAAGCCGAAGCAGGAAGATTGCTTGATGCCAGGCATTCAAGACCAGCATGGGCATCATAGTGAGATCCTGTCTCTACAAAAATTAATTAACATTAAAAATTAAAAAGATGGCTGGCATGGTGGCTCACTCCTGTAATCCCAGTACTTTGGGAGGCCAAGGCATGGTGGTGCATGCCTTTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAATTCAGGAGGCGGAGGTTACAGAGAGCCGAGATGGTGCCACTGCACTCCAGCCTGGGCGACAGAACGAGACTCTGTCTGAAAAAAAAAAAGAAAATTAAAAAGACCAGAATAAAGCTAAAGATTTAAAATAGCCTATAGGTTCCTACCAGAAGTTACCAGCTACCTCTCTGATAGTCTTTCCCTACAATATCCTCCTGGATTATTACATTTTAGCACCTTGACCTATCTGATGTCCTGCATACACAGGCATGGTCCTGCTCAGGGTTTGCCTTCTCTGCTCCCTCTTTCTTGGAATGCTCTTCCCCTAATTGTTGCATAGTGTGTTTCTTTACATTATTAAGCTATCCTCTAGTCTCACCTCAGTGAAACCTTTCCTGACTCCCCCCATGTACATCTCACCCCCACATAGATATTGAACTACCTGTTTCCCCTTACCCTGCTTAATTTTTCTCTTTAATGCACTTATTCCCATGTATTCTTTAATTCCGTATCAACTGTCTACCACACTAGAATATGAGCTCTATGAGAGCAGGCTTTATTTTGTAAACTGCTACATTTCTATCTCCTAGAATAGTACTTGAATATAGTAGTAGATACTTAATAAACACTTGTTATATTAGTATAATAAATGAACTAATCTCAGGAATGCCTTGGTTTTGTGGATAGACAGGTAGGGATGGGAACTTGGGTGATGTATTTTCTGAAGTTTTTATTTTTAAGCTTATTATTATTTTGAGATGGAGTCCAGCTCTGTCGCCCAGGTTGGAGTACAGTGGCGCGATCTTGGCTCACTGCAACGTGCACTTCCCCGGTTCAAGCGATTCTCCTGCCTTAGCCTCCCAAGTAGCTGGGATTACAGGCGCATGCCACCATGCCCAGTTAGTTTTGGTATTTTTAGTAGAGACAGCGTTTCACTGTGTTGGCCAGGCTGGTCTCGAAATCCTGACCTCATGATCCGCCCGCCTCGGCCTCCCAAGTGCTGGGATTACAAGCATGAGCCCCCGTGTCTGGCCTTATTTTCTTTTTTTTGAGACAGAGTCTTCCTCTGTCACCTAGGCTGGAGTGCAGTGGCACGATATTGGCTCACTCTGCAACCTCCACCTCCAGGATTCAAGTGATCCTTCTACCTTAGTCTCCAAAGTAGCTGAGACCACAGGCATGCGCCACCACGCCCGGCTAATTTTTGTATTTTTAGCGTAGACAGGGTTTCACCATATTGTCCAGGATGATCTGGAACTCCTGAGCTCAGGTGATCCACCCACCTCAGCCTCCCAAAGTGCTAGGATTACAGGCATGAGGCACCATGCCCGGCCTTAAGCTTATCATTTTCTAAATTTCCTTTAGTGAGTACTTATTACACTGTTTTTACAAAGTAATCACAAACCAAACATCATGCCTCTTCTGAAGTGATCTAATAAGAGTACACAGTACCATCTGTAAAGTGTTCTTGCCAGAAAGTTGAACCTGAATGATTAAGCCTGTAAGTCTAGTTTATAGGAAATAAGGCTAGAGGAACAAGTTAAACCTCACCATAGGGTTATACAATCAGCAAAATCCAGAATGGGGGAAACTCCACAGGTCAAATGACCTAATTTTAAAAATAAATGACAAGGGAGAAAAAGTAAGAGACACCTATAGATCAGAAGACACTTGGGGCTGGGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCGGCCAACATGGTGAAACCCCAACTCTACTAAAAATACGAAAAATCAGCCGGGCGTGGTGGCGCACGCCTGTAGTTCCAACTACCTGGGAGGCTGAGGCAGGAGAATCACTTGAACTTGGGAGGCAGAGGTTGCAGTGAGCCGAGATCGCACCATTGCATGCCAGTCTGGGCTACAAAAGCAAAACCCCATCTCAAAAAAAAGAAGACACTTGGGTTTGGGTGTGTTGGCTCATGCCTGTAAACCCCGTGCTGGGAGGATTGCTTGAGCCCAGGAGTTCAAGGCTGCAGTGAGGTATGTTTGCACCACTGCACTCCAGCCTAGGTGACAGAGTGTGACCTTATCTTAAAAGTAATAATAATTAAAATAATCTGGGGTAGGGGTGGATATGGGTGAAACAGCTTGGCCATGAGTTGATGGTTGTTGGACCAGGGTGATGGTCCATATAGTTCATTTTATTATTTTATTTACTTGAAATTTTGAAATACTTGAAATTTTCCATATTAAGTTAAAAAGGCATTTACAGTAAACAAAAAAAAGTTCTAGGAAGGAATTCAAAAGAAATATAAGCAGAAAATTTTGTCTTTATGGAGCTTAAAGATGAGATGTGCACCCACAGTGATAGTGCAGAAAAATATATCACTGGAAATGAATTCGTACGAACTATTATCAACTAATCTTTTAAATGCTGATGATAGTATAGAGTATTGAAGGGATCAATATAATTCTGTTTTGATATCTGAAAGCTCACTGAAGGTAAGGATCGTATTCTCTGCTGTATTCTCAGTTCCTGACACAGCAGACATTTAATAAATATTGAACGAACTTGAGGCCTTATGTTGACTCAGTCATAACAGCTCAAAGTTGAACTTATTCACTAAGAATAGCTTTATTTTTAAATAAATTATTGAGCCTCATTTATTTTCTTTTTCTCCCCCCCTACCCTGCTAGTCTGGAGTTGATCAAGGAACCTGTCTCCACAAAGTGTGACCACATATTTTGCAAGTAAGTTTGAATGTGTTATGTGGCTCCATTATTAGCTTTTGTTTTTGTCCTTCATAACCCAGGAAACACCTAACTTTATAGAAGCTTTACTTTCTTCAATTAAGTGAGAACGAAAAATCCAACTCCATTTCATTCTTTCTCAGAGAGTATATAGTTATCAAAAGTTGGTTGTAATCATAGTTCCTGGTAAAGTTTTGACATATATTATCTTTTTTTTTTTTTTTGAGACAAAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAACCTCCGCCCCCCGAGTTCAAGCGATTCTTCTACCTCAGCCTCCCAGGTAGCTGGGACTACAGGCACCCGCCACCATGCTTGGCTAATTTTTGTACTTTTAGTAGAGATAAGGTTTCACCATATTGGCCAGGCTGGTCTCGAACTCCTGACCTTGTGATCCACCTGCCTCGGCCTCCCAAAGTTCTGGGATTACAGGCGTGAGCCACCACACCCGACTGACATATATTATCTATTAGGATGTAACATCATTTTGAACAGTGTTTTGTATTTTTTGTGTCCATCAGTGAAAGCAAACTGCAAGCAGTTTTGAAATAAGCACATTGTGTTTGAGCCTTCCCAGTTTCTCCTTTCTGTTCATTTCTGCATATCCTTATGCATTCCCCCTTCTAAGGGTCAGTGTTTGCCCGCTTTGTAATCATTGTGAAGACAGGAAAGGACCTGATACCAGTTTCTATTTAGGCCAAAATTCATTTATAGCAGTGATTCAAGTTATATTTACGTATTTGATGATCTTGTCTTTTGAAATGAAAATGTTTGTTTCTTAATAAAAGAATTTCAGAAAAAGTAGAGTAGGTAATTTAGTAGAACAAGTGGGCTTTCTCCTTTTCTTTATGTTAAGCTATGGCTCACATCTTACCTTAAATGTCAACTAATTTGTTTTTAAGTATTTATGTACCTGGTACATAACCTGGTACCAGGTACAAACTATGTACTTGGTAAAAAGTTTATTAGCACAAAAAGGTATATGATGCAAAGTATACTTCCCTCTTACCCTACAACCCCTGCCTCCCTGTTCCCTCCCCAGACAACCACAATGATCAATTTCTTATGTATCCTTTGAGGAATTTTTAAATTCCAGAGTTCTTAACTTGGGGTTTATGAATAGTCTTTATGAATTTCCTAGAATTATATTTAAATTGTATTCAAAACTATGGCCATGTACATTTTTCTGGGAAGATAGTCCATAATTTTCATCTGAGTGAGCTAAGATCATGCCACTGCATTCCAGCCTGGGCGACAAGAGGGAGACTCAAAAAAAAAAAAAAAAGTCCCAGTATTTACTACAGAGAGCTAAAGATTAACCTTTAAAGCCCTGGGGCTTTCAATTTATCTGGATGAGAATCTTTCTGGAATGAACTGTATGTTTTCTTGTCAGCTTGAGTAACAAATGCTGAACATACTATACTATTATTACAGGGACTCAAGGGCCCAGTGTGGTAGCTCCTGCCCATAACCCCAGCACTTTGGGAGGCCAAGGCAGGAAGATCACTTAAGGCCAGGAGTTCGAAGCTGTAGTGAGCTATGATCACACCACTGCACTCCAGCCTAGATGACAGAGTGAGACCCTGTCTTTTTTTTTTTTTGAGATGGTGTTTCACTCTATTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCTTGAGTAGCTGGGATTACAGGCATCTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTCGAGACAGGGTTTTCACCATGTTGGCCAGGCTGCTCTCAAACTCCTGACTTCAGCTACCTTGGCCTTAAAAAGTGTTGGGATTACAGGTGTAAGCCACCGCGCCTGGCTGACCCTGTCTCTTAACAAAAAAAGAGAGATTAAGTTATGAATATAGTTGCTTTGAGAACTTGTGGAAGAAGGAAATTATAGGCTTATAGGCAGAGATAATAATACGAGCAAATGTACAAATAAAAGAAAATAGAGGACGGGCGCGGTGGCTCACGCCTATAATACCAGCACTTTGGGAGGTCGAGGTGGGCGGATCACGAGGTCAGGAAATTAAGACCATCCTGGCCAAAATGGCGAAACACTGTCTCTACTAAAACACACAAAAAACTAGCCTGGCATGGTGGCACGTACCTGTAGTCCCAGCTACTTGGTAGGCTGCGGCAGGGGTATCACTTGAACCTGGGAGGCAGAGGTTGCCCTGAGCCGAGATCATGCCAATGCACTCCAGCCTGACAACAGAGTGAGACTCTGTCTGAAAAAAAAGAAAAGAAAAGAAAATACATCCAGGAAAAATAAGCTAACTTTGCATATGTGTATAGGAGTTGTGTTAGAAAAGGAAGAAGCCCTCAAAGATGGGAAGCCATTTGCAAGAAAGAGAAGGTCCAAGAGGAGGCAGAAGGGATTGGAAATAGAAAAAGGATGTAAGAAAGAGTTGATTATTACTCATAAACAGTAATGAAGGAAAAGGAGAGTAATTCTACAGGAAGATGCTGAGGTGCTTTGAGCCCAGTGAAGTTGGAGGTAAAGACAGCTGTTGAGGCCGGGCACGGTGGCTCACGCCTCTAATCCTAGCACTTTTGGAGCCCAAGGCAGGTGGATCACCTGAGGTCAGGAGCTCAAGACCAGCCTGACCAACATAGAGAAACCCCATCTCTACTAAAAATACAAAATTAGACGGGCGTGGAGGCGCATGCCTGTAATCCCAGTTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGAGATTGCGCCATTGCACTCCAGCCTGGGCGACAAGAGTGAAAACTGTCTCAAAAAAAAAAAACAACAAAAAACAGCTGTTGAGATTGAGAGGATTAGAGTTGGCAACTGGAGAAGAGTGAGAAGCTTGGTTTCAAGCTTGTGATAGTCAGGATTGTGATAGTCAGGAAAGAACCAGTCATAAAGATATATGTGTGTGTATACATATAAATATGTTATATATATGTGTGTGTGTGACACATATATATTTTTGTTTGTTTCTTTGAGACAGTGTCTCCCTCTGACACCCAGGCTGGAGTTCAGTGGTGTGATCATAGTTCACTTTTACCTTGCAATCTGGGTTCAAGCAATCTCTCATCTCAGCCCCTCAAGTAGCTAGGACTACAGGTACATGGCATTTGCCCAGCTAATTTTTAAGTTTCTTGTAGAGATGGGCCAGCCATATTTTAAATTGTGTTTTGAATGTTATATTAGAATTAAAAGTCCAAAGCCGGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCGGATCACGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATATGGTAACACCATCTCTACTAAAAATACAAAAATTAGCTGGGTATGGGGGCACATGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGAGGAACCTCTTGAACCCAGGAGGCAGAGGCTGCAGTGAGTTGAGATCGTGCCACTGTACTCTAGCCTGGGCGACAGAGCAAGATTCCGTCTCAAAAAAAAAAAAAGTCCAGTATAATGCCCATGTGATAGATCGACTTTTTCATGAAATCTCTTCTGTAATATCAATATAATCTGAATAACACTTTGATCTATATGATGAGAAAGCTGGGAGCCTGGGAGCGATACCCCCATGCTTTTGTTGTATTAATTGTATTTTCTACGGATAAACTCTAATTGCTAAAAATAAAACAACTTTATTGACCCAAGCAAGCCTAAAGTTCTGAAATCTTTTTTTTATTTTTGTTTGTTTGTTTGTTTGTTTTTGTTTGTTTTGTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCGGTGGTGCAGTCTCGGCTCACTGCAAGCTCCACCTCCCGGGTTCACACCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGACGCCTGCCACCACGCCCAGCTAATTTTTTTGTATTTTTAGTAGAGAAAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCTGCCCGCCTTGGCCTCCCTAAGTTCTGGGATTACAAGTGTGAGCCACCACGCCCGGCTGTTTTTTTTTGTTTTGTTTTGAGACGGAGTCTCACTGTGTTGCCCAGACTGGAGTGCAGTGGCATGATCTCAGCTCACTGCCACCTCCATCTCCTGGGTTCAAGCAAATCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCATGTGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACTATGTTGGCCAGGCTGGTCCAAAACTCCTGACCTCAGGTGATCTGCTCGCCTTGGCCTCCCACAGTGCCAGGATTACAGGCATGAGCCACCTTGCCCAGCCAGTTCTGAAATCTTTTATGAAGCCTATAAAAAAAGATAATAATACCAATCTAGAAAATATTTCTTAAGGCAGTCATGCATTAGTTTGAACTTTCCAAACAAAAAAATGCAATGTGTAATACTTTTTTTTTTTTTTTTGAGATGGAGTCTTGTTCTGTTGCCCAGGCTGGAGTGCAGTGGTACAATCTCGGCTCACTGCAGCCTCTGCCTCTCTGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGTGCACCACCATGCATGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGACAAGGCTGATCTCGAACTCCTGACCTCAGGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTGAGATTACAGGCATTAGCCACCACGCCCAGCCTTTTATTTTAGTAGAGACCATGTTTCACCATGTTGACCAAGCTGGTCTTGAGCTGACCTCAAGTGATCCGCCCACCTCCACCTCCCAAAATGGTGGGATTATAGGCATGAGCCACCGCACCCAGCCTGTAATACTTTTTTGAAGATCTAGAACCACATTGTTCAAAGAGATAGAATGTGAGCAATAAATGTAACTTAAATTTTTCAACAGCTACTTTTTTTTTTTTTTTTTGAGACAGGGTCTTACTCTGTTGTCCCAGCTGGAGTACAGTGGTGCGATCATGAGGCTTACTGTTGCCTTGACCTCCTAGGCTCAAGCGATCCTATCACCTCAGTCTCCCAAGTAGCTGGGACTGTAAGTGCACACCACCATATCCAGCTAAATTTTGTGTTTTCTGTAGAGACGGGGTTTCGCCATGTTTCCCAGGCTGGTCTTGAACTTTGGGCTTAACCCGTCTGCCCACCTAGGCATCCCAAAGTGCTAGGATTACAGGTGTGAGTCATCATGCCTGGCCAGTATTTTAGTTAGCTCTGTCTTTTCAAGTCATATACAAGTTCATTTTCTTTTAAGTTTAGTTAACAACCTTTATACATGTATTCTTTTTCTAGCATAAAGAAAGATTCGAGGCCGGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGATGGGCACATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCGCCTCTACTAAAATTACAAAAAGTTAGCCAGGCGTGGTAGCGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCAGAGCTTGCAGTGAGCAGAGATTGTGCCACTGCACTCCAGCCTGAGAGACAGAGCGAGACTCCGTCTAAAAAAAAAAAAAAAGATTCGAATCCTTATCTTGGTTGATTTTTGCGTATCTAGTTCCACTGAATTATTTATATAATTGTATAGACTACAGCACGAGACAGCTTAGCTTGTCACTCTACTGTACTATATTCTGCAGTACTATCATAAGGGAATTTCCTCCCTACCCCTGCTCTGAATTGTTCAATTGTACTATTTGCTGGAGTAATGCTTGATGCCTTCTTGATCCATTATACTAGAGTATATGTAGTATTTGTAGATTCTGAAGGAGTGGGAGCCTCTATTCTGAGTTTTAAAGGTACTTATGTACAGTGGAGGTAGCTTTTTGACAGCCTCATCTTCCAAACTATAGAGTCATTGTTTTGTTGAGTGCAATATGGTACTTGAAGCATCTATATCGGCGAAGAAGGACCCAAGTCTCCTTGACCTTACCTACCTACATTCACTTTCTCTGGTAGGAAGATTGTGGGTGCCTCTCTCCAGACTTAGTTTCCATGTCAAAAAAGAAAAAAGGAAGATTGTGGGCTTTGCTACAATCCAATTCTGGATCCAATATAACCTTCATTGCTTAATTACTGTGTGATCTGGGACAAGCCTCTACTCTATAAAAATGAAGATAAGGCCAGGCTTGATGGCTCATGCCTGTAATCCCAGCACGTTGGGATGCCAAGGCAGGAGGATCACTTGAGGTCAGGAGTTCGAGACCAGACTGGGCAATATAGTGAAACCACATCTGTACAAAAATAAAGATAGAAAGTAGCCCAGCGCAATGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAAGCAGGCGATCACTTGAGGTCGGGAGTTCAAGACTGTAGACAGATAGATAGGTAGGTAGATAGATAGAGATATAGATATAGTTGGGGTTTTTTTGTTTTGTTTTGTTTTGTTTTTGAGATGGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCGCGATCTCAGTTTACTGCAACCTCCGCCTCCCGGGTTCAAGAGATTCTCCTGCCTCAGCCTCCTGAGTAGCCAGGATTACAGGCATATGCCACCATGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCTCCGTGTTGGTCAGGCTGGTCTTGAACTCCTGACCTCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCGCTCCTGGCCTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTCCTCTGTTGCCCAGGGTGGAGTGCAGTGGCACTCTTCTCAGCTCATTGCAACCTCTGCCATCCTGGGTTCCAGTGATTCTCATGCCTCAGCCTCCCAAGTAGCTGGGACTCAGGCGTGTGCCCACCACGCCTGGCTAATTTTGTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTAGCCAGGCTGGTCTCAAACTCCAGGCCTCAAGTGATCTGCCTGCCTCAGCCTCCTGGGATTGCAGACATGAGCCACTGCACCCGGCCAAGAGAGGGTAATAAATGTTAAATTACCTGGCTAGTAAAAAATATTCTCTAAGTGTCTTTTCTCACAATTCCCAATGCCTTTTTTTTTTTTTTGGCACAATCTCACTCTGTTGCCCAGGCTGGAATGCAATGGTGCAATATTGGCTCACTGTAACCCCCGCCTCACAGGTTCAACTTATTCTCATGCCTCAGCCTCCCGAGTAACTGGGACTACAGTGCACCACCACCACACCCAGCTAATTTTTGAATATTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGGCCTCAAGTGATTCACCCACCCCGCAAGTGCTGGGATTACAGGTGTGGACCACCGTGCACAGCCCTAGTGACTTTTTTTTTAGCCCCTTAATCTTTTCTTTCCTGGGTCTCTTCATTGTCAGTGTCTGCTATTTACTCCCTACCTAGTCACCCCCTTCACCAGTATATTATGTCCTTTATGTTTTATTTTGCAGGATCTTATTTTGCTTTTCTATTGAATCCCCTCCATCTAGAATAGTACTAGACATAGTAAATATTGGTTGTATGAGTGAATCGCTGCTTTTAATTATCATCACCATTGCTCTCTCTACTTCTGGTCTATGATCCACTTTGAGTTAACTTTTGTTATTTGGTGTGAGATAGGAGTATAATTTCATTCTTTTACATGTGGTTATACTTTTGTCTCAACACTGTTTGTTAAAAACACAAAAAGTATTATTTTCCCATTTAATCATCTTTGGCCTGGGCACGGTGGCTCATGCCTGTAATCCCAGCACTCTGGAAGGCCAAGGCAGATGGATCAATTTGAGGCCAGGAGTTCAAGACTAGCCAACATGGTGAAACTAAAAATACAAAAAATTAGCTGGGTATGGTGGTGCATGTCTGTAATCCCAGCTACTCGGGAGGCTGAGGCACGAGAATTGCTTGAGCCTAGGAGGTGGAGGTTGTAGTGAGCTGAGATTGTGTCACTACCCTCCAGCCTGGGTGATAGAGTGAGTCTGTCTCAAAAAAAAAAAAAAAAAATTAAGAAAATAAAAATCGTCGGCCAGGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCAGAGGCGGGCAGATCACGAGGTCAGGAGATGGAGACCATCCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAAATAAAAAAATTAGCCGGGCATGGTGCTGGGCGCCTGTAGTCCCAGCTGCTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGTGGAGCTTGCAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGAGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAATTGTCTTGGTATTTATTATTGTTGAAAATCGCTTGATCACAGATGTATGTATGAGTTTATTTCTGTACTGTCAATTCCATTTTATTGATGTATGTGTCTATTCTTATGCTATTACCACACTTTCTTGATTACTATAGCTTTGTGGTGAGGTGTTGAGATTTTAAACTAATTATAAGCATCTTACATGAACTACTTACCGTTTATATTTGATTATGCAGCATGAAATAATTATGAATATATCATTAAATATGCCATATTAACTTTTATTAAGTTTTATGTGATCATAACAGTAAGCCATATGCATGTAAGTTCAGTTTTCATAGATCATTGCTTATGTAGTTTAGGTTTTTGCTTATGCAGCATCCAAAAACAATTAGGAAACTATTGCTTGTAATTCACCTGCCATTACTTTTTAAATGGCTCTTAAGGGCAGTTGTGAGATTATCTTTTCATGGCTATTTGCCTTTTGAGTATTCTTTCTACAAAAGGAAGTAAATTAAATTGTTCTTTCTTTCTTTATAATTTATAGATTTTGCATGCTGAAACTTCTCAACCAGAAGAAAGGGCCTTCACAGTGTCCTTTATGTAAGAATGATATAACCAAAAGGTATATAATTTGGTAATGATGCTAGGTTGGAAGCAACCACAGTAGGAAAAAGTAGAAATTATTTAATAACATAGCGTTCCTATAAAACCATTCATCAGAAAAATTTATAAAAGAGTTTTTAGCACACAGTAAATTATTTCCAAAGTTATTTTCCTGAAAGTTTTATGGGACATCTGCCTTATACAGGTATTAGAAACTTACTGCCTTTCTCTAATGCTTCTAGTGTAAAAACTTGCAGACTTATGTAAAGTAGGGCTGTATCGCCGTGCCCCCATTGTCTGTTAATCTTGTTTTTATATTTTTGATTGTGTTTCCTTTTCTTTTTTTTTTTTTTTTTAAGACAGGGTCCTGCTCTGTCACTGAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGTAGCCTCTGTCTCCCAGCCTCTTCCTGCCTTAGCCTCCCAAATAGCTGGGACTACAGGCACACGCTACCATGCCCGGCCAATTTTTGTATTTTTTGTAGAGATGAGGTTTTACCATGTTGCCCAGGCTGGTAACTCCTGAGCTCAGGTGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGGTTCACAGGTGTGTGTTTATTTCTATCTAATTATTTACACAAACACAATGTATTTATATATTGTGTATCTCTTCTGCTACAATGTAAATTCTATGAGAGTAGTAATTTTGTCTGTCTCAACACTGTTTTTCCTAAGTTTGGTACATAGTAGGCACTCAGATGCTTAAAGGAATGAATGAATTGTGCTTTAATTCCACTTTACTAAACCCAAATCTCCCTTTGGACATTGTTATCTATGTGTTTTCAAAGAAGTATAATCATAATTTGACAGAAATCCTTGAGAGGCAGAACTAAGTGAGGGATTGGGCAGGGTTCAGATGTTAAGAACAGTAAGCTCAGCAGGGTGTGATTGCTCATGCCTATAACCCTAGCACTCTAGGAGGCTGAGGTGGGATGATTGCTTGAGGCCAGGAGTTTGAAATCAGCCTGGGCAACATAGTGAGACCCCATCACTACCAACAAAATAAATAAATAAATGTACATGGTGGCATATGCCCATAGTCCTAGCTACTTGGGAGGCTATAGTGGGAGGATAGCTTGAGTACAGAAGTCTGAGGCTGCAGTGAGCTATGATTGTGGCACTGCATGCTAGCCTGGGCAATAGAGCAAGACCCTGTCTCTAAATTAAACAAAAAAAAAAGTACTCTAGTTTTCTATGCAATGCATTATATCTGCTGTGGATTTAGGGCAGTATTATATCAGATAATTTTAGGCATTTGGTAGGCTTAAATGAATGACAAAAAGTTACTAAATCACTGCCATCACACGGTTTATACAGATGTCAATGATGTATTGATTATAGAGGTTTTCTACTGTTGCTGCATCTTATTTTTATTTGTTTACATGTCTTTTCTTATTTTAGTGTCCTTAAAAGGTTGATAATCACTTGCTGAGTGTGTTTCTCAAACAATTTAATTTCAGGAGCCTACAAGAAAGTACGAGATTTAGTCAACTTGTTGAAGAGCTATTGAAAATCATTTGTGCTTTTCAGCTTGACACAGGTTTGGAGTGTAAGTGTTGAATATCCCAAGAATGACACTCAAGTGCTGTCCATGAAAACTCAGGAAGTTTGCACAATTACTTTCTATGACGTGGTGATAAGACCTTTTAGTCTAGGTTAATTTTAGTTCTGTATCTGTAATCTATTTTTAAAAAATTACTCCCACTGGTCTCACACCTTATTTTATCAATCGTAAGGTGCACATTTTTCACATCTTAACATCTCTGAAATTGGGAACATTTTACTATTGAGGGTGTGTCATTTGTTTAATTTGTGTGCTTTCTTTCTTAGTGATACAGAAAATAATAGTGCAACTTACATTGTTGGTGTCTTAGCTTTAGTGAAATACAGTATTGATAGGCAAATTTCTTAGTGTTAAGGTAGAAAACAAGGACTCTAAATAACTTTGATGGTCTGTGTATTTGTTTTTGTTTCCTAGGAGTAAAATTTCCAGTTGATTTTTTAAAATTTGATTTTTAAAAAAAATCACAGGTAACCTTAATGCATTGTCTTAACACAACAAAGAGCATACATAGGGTTTCTCTTGGTTTCTTTGATTATAATTCATACATTTTTCTCTAACTGCAAACATAATGTTTTCCCTTGTATTTTACAGATGCAAACAGCTATAATTTTGCAAAAAAGGAAAATAACTCTCCTGAACATCTAAAAGATGAAGTTTCTATCATCCAAAGTATGGGCTACAGAAACCGTGCCAAAAGACTTCTACAGAGTGAACCCGAAAATCCTTCCTTGGTAAAACCATTTGTTTTCTTCTTCTTCTTCTTCTTCTTTTCTTTTTTTTTTCTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTGGCCCAGGCTAGAAGCAGTCCTCCTGCCTTAGCCCCCTTAGTAGCTGGGATTACAGGCACGCGCCACCATGCCAGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCATCATGTTGGCCAGGCTGGTCTCGAACTCCTAACCTCAGGTGATCCACCCACCTCGGCTCCCCAAATTGCTGGGATTACAGGTGTGAGCCACTGTGCCCGGCCGGTAAAACCATTTTCATTTATTCTGGCAACATCTCTTTATTGAGCATTGTGAATATGTTAGTGAATGTGCTAGATGCTCATAGATTTATATAAAAAGTTAGTGAAGAAGGAAAGATGGTATATTAAGTGGTTAGACAAGTGTTCTAATCAGTTAGAGTTCAGAGAAGGTCAGGGTACCTGATATAATCAAGAGAGAGACCTTACAGCCAGGTGAGGTGAATGTACCTATAATCCCAGCTACTTAGGAGGCTGAAATGGGAGGATCACTTGAGTCCAGGTTTGAGACCAGCCCAGGCAACATAGCAAGATCCCCATCAGATACACCAAAAAGACAGATTTCTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCGCCCAGGCTGGAGCGCAGTGACACGATGTCAGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGTTGGGACTACAGGGGTACGACACCAGACCTGGCTAATTTTTGTAATTTTAGTAGAGTCGGGGTTTCACCATATTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCTCCTTGGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCAAGCCCGGCCAAAAAAGAGAGCTCTTATAGGCCCTTCCTTGCTTTGGAGCTTTATCTGCTCTGTGATGCTTATCTAAAATAGCCATAAGGTCACTGATATTTTTAAGCATTTGGAAATTACTTCAGCTGGGTGCCATGGCTCATGCCTATAATCCCAACCCTTTGGGAGGCTGAGGTAGGAGGTCCTTTGAGCCCAGCTTGGGCAACACAGTGAGACACTGTCTCTGCAATTAAAAAAAAAAAAAAGTAGCTGGGTGCCGTGGCTCACGCCTGTAATTCCAGCACTAGGAGGCTTGAGGATTGCCTGAGCTCAGGAGTTCAAGACCAGTTTGGGCAACATAGCAAGTCCTTGTCTATATTAAAAGTTTTTTTAAATTATCTGGGCATGGTGGTGTGTGCCTGTAGTCCCAGCTACTTGGGAAGCTGAGACAGAAGGATCACTTGAGTCCAGGAGATGTAGACTACAGTGAGCTATGATCACTCCACTGCACTTCAGCGTGGGCGGCAAAGCAAGATCTAGTTGCAAAAAAAAAAAGAACTGGCTGGGTGCGGCGGCTAACACCTGCAATCCCAGCACCTTGGGAGGCTGAGGCCAGTGGATCATGAGGTCAGGAGATTGAGACCACCCTGGCCAACATGGTGAAACCCGGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACGTGCCTGTAATCCCAGCTACTCCAGAGGCTGAGGATGGAGAATCACTTGAACCTGAGAGTCGGAGGTTGCAGTGAGCCGAGATTGCGCCACTGCACTCCAGCCTGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAGCTTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGTCAAGTGGATCACGAGGTGTGGAGATCAAGACTATCCTGGCTCACATGGTGAAAGCCCGTCTCTACTAAAAACACAGAAAAATTAGCTGAGCGTGATGGCGGACTCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATAGCATGAACCCGGGAGGTGGAGCTTGCAGTGAGCCGAGATCCCGCCACTGCGATCCAGCCTGGGCGACAGAGTGAGACTCTGTCTCAAAAAAAAAACAAAAAAACTTAGCTGGGCGTGGTGGTATGCACCTGTGGTCCTAGCTACTTGGGAGGCTGAGGCTGGAGCATTGCTTTAACATAGAGAGTCAAGGCTGCAGTTGAGCTATGACTGTGCCACTGGACTCCAGCGCAGGTGACTGAGACCCTATCTTTTAAAAAAAGGGAAAATTACTTGAACTTAAAAGGTGTAATTGTTAAAGAAAATGTAGTGATTTGCTCTGTTGTTACTTATATGTGCATGAATGATGGAGATCTTAAAAAGTAATCATTCTGGGGCTGGGCGTAGTAGCTTGCACCTGTAATCCCAGCACTTCGGGAGGCTGAGGCAGGCAGATAATTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACGTACCTGTAATCCCAGCTACTCGGGAGGCGGAGGCACAAGAATTGCTTGAACCTAGGACGCGGAGGTTGCAGCGAGCCAAGATCGCGCCACTGCACTCCAGCCTGGGCCGTAGAGTGAGACTCTGTCTCAAAAAAGAAAAAAAAGTAATTGTTCTAGCTGGGCGCAGTGGCTCTTGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCTCGAGTCCTAGAGTTCAAGACCAGCCTAGGCAATGTGGTGAAACCCCATCGCTACAAAAAATACAAAAATTAGCCAGGCATGGTGGCGTGCGCATGTAGTCCCAGCTCCTTGGGAGGCTGAGGTGGGAGGATCACTTGAACCCAGGAGACAGAGGTTGCAGTGAACCGAGATCACGCCACCACGCTCCAGCCTGGGCAACAGAACAAGACTCTGTCTAAAAAAATACAAATAAAATAAAAGTAGTTCTCACAGTACCAGCATTCATTTTTCAAAAGATATAGAGCTAAAAAGGAAGGAAAAAAAAAGTAATGTTGGGCTTTTAAATACTCGTTCCTATACTAAATGTTCTTAGGAGTGCTGGGGTTTTATTGTCATCATTTATCCTTTTTAAAAATGTTATTGGCCAGGCACGGTGGCTCATGGCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCACCTGAGGTCAGGAGTGTGAGACCAGCCTGGCCAACATGGCGAAACCTGTCTCTACTAAAAATACAAAAATTAACTAGGCGTGGTGGTGTACGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCAACTGAACCAGGGAGGTGGAGGTTGCAGTGTGCCGAGATCACGCCACTGCACTCTAGCCTGGCAACAGAGCAAGATTCTGTCTCAAAAAAAAAAAACATATATACACATATATCCCAAAGTGCTGGGATTACATATATATATATATATATATATATTATATATATATATATATATATGTTATATATATGTTATATATATATAACATATATATATGTTATATATATGTTATATATATATAATATATATATGTTATATATATGTTATATATATATATACACACACACACACATATATATGTATATATATATACACACACACACACAAATTAGCCAGGCATAGTTGCACACGCTTGTAGACCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCTCTTGAACTTAGGAGGCGGAGGTTGCAGTGAGCTGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCAGGACTCTGTACACCCCCCAAAACAAAAAAAAAAGTTATCAGATGTGATTGGAATGTATATCAAGTATCAGCTTCAAAATATGCTATATTAATACTTCAAAAATTACACAAATAATACATAATCAGGTTTGAAAAATTTAAGACAACAGAAAAAAAAATTCAAATCACACATATCCCACACATTTTATTATTACTACTACTATTATTTTGTAGAGACTGGGTCTCACTCTGTTGCTTATGCTGGTCTTGAACTCCTGGCCTCAAGCAGTCCTGCTCCAGCCTCCCAAAGTGCTGGGATTATAGGCATGAGCTACCGCTCCCAGCCCCAGACATTTTAGTGTGTAAATTCCTGGGCATTTTTTCCAGGCATCATACATGTTAGCTGACTGATGATGGTCAATTTATTTTGTCCATGGTGTCAAGTTTCTCTTCAGGAGGAAAAGCACAGAACTGGCCAACAATTGCTTGACTGTTCTTTACCATACTGTTTAGCAGGAAACCAGTCTCAGTGTCCAACTCTCTAACCTTGGAACTGTGAGAACTCTGAGGACAAAGCAGCGGATACAACCTCAAAAGACGTCTGTCTACATTGAATTGGGTAAGGGTCTCAGGTTTTTTAAGTATTTAATAATAATTGCTGGATTCCTTATCTTATAGTTTTGCCAAAAATCTTGGTCATAATTTGTATTTGTGGTAGGCAGCTTTGGGAAGTGAATTTTATGAGCCCTATGGTGAGTTATAAAAAATGTAAAAGACGCAGTTCCCACCTTGAAGAATCTTACTTTAAAAAGGGAGCAAAAGAGGCCAGGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAAGTGGGTGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTAGCCAACATGGAGAAACTCTGTCTGTACCAAAAAATAAAAAATTAGCCAGGTGTGGTGGCACATAACTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGTGGAGGTTGCGGTGAACCGAGATCGCACCATTGCACTCCAGCCTGGGCAAAAATAGCGAAACTCCATCTAAAAAAAAAAAAGAGAGCAAAAGAAAGAATATCTGGTTTTAAATATGTGTAAATATGTTTTGGAAAGATGGAGAGTAGCAATAAGAAAAAACATGATGGATTGCTACAGTATTTAGTTCCAAGATAAATTGTACTAGATGAGGAAGCCTTTTAAGAAGAGCTGAATTGCCAGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACCTGAGGTCGGGAGTTCAAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAAAAAAAAAAAAAAAATTAGCCGGGGTGGTGGCTTATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAAGCAGAGGTTGCAGTGAGCCAAGATCGCACCATTGCACTCCAGCCTAGGCAACAAGAGTGAAACTCCATCTCAAAAAAAAAAAAAAAGAGCTGAATCTTGGCTGGGCAGGATGGCTCGTGCCTGTAATCCTAACGCTTTGGAAGACCGAGGCAGAAGGATTGGTTGAGTCCACGAGTTTAAGACCAGCCTGGCCAACATAGGGGAACCCTGTCTCTATTTTTAAAATAATAATACATTTTTGGCCGGTGCGGTGGCTCATGCCTGTAATCCCAATACTTTGGGAGGCTGAGGCAGGTAGATCACCTGAGGTCAGAGTTCGAGACCAGCCTGGATAACCTGGTGAAACCCCTCTTTACTAAAAATACAAAAAAAAAAAAAAATTAGCTGGGTGTGGTAGCACATGCTTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCAGGGAGGCGGAGGTTACAATGAGCCAACACTACACCACTGCACTCCAGCCTGGGCAATAGAGTGAGACTGCATCTCAAAAAAATAATAATTTTTAAAAATAATAAATTTTTTTAAGCTTATAAAAAGAAAAGTTGAGGCCAGCATAGTAGCTCACATCTGTAATCTCAGCAGTGGCAGAGGATTGCTTGAAGCCAGGAGTTTGAGACCAGCCTGGGCAACATAGCAAGACCTCATCTCTACAAAAAAATTTCTTTTTTAAATTAGCTGGGTGTGGTGGTGTGCATCTGTAGTCCCAGCTACTCAGGAGGCAGAGGTGAGTGGATACATTGAACCCAGGAGTTTGAGGCTGTAGTGAGCTATGATCATGCCACTGCACTCCAACCTGGGTGACAGAGCAAGACCTCCAAAAAAAAAAAAAAAAGAGCTGCTGAGCTCAGAATTCAAACTGGGCTCTCAAATTGGATTTTCTTTTAGAATATATTTATAATTAAAAAGGATAGCCATCTTTTGAGCTCCCAGGCACCACCATCTATTTATCATAACACTTACTGTTTTCCCCCCTTATGATCATAAATTCCTAGACAACAGGCATTGTAAAAATAGTTATAGTAGTTGATATTTAGGAGCACTTAACTATATTCCAGGCACTATTGTGCTTTTCTTGTATAACTCATTAGATGCTTGTCAGACCTCTGAGATTGTTCCTATTATACTTATTTTACAGATGAGAAAATTAAGGCACAGAGAAGTTATGAAATTTTTCCAAGGTATTAAACCTAGTAAGTGGCTGAGCCATGATTCAAACCTAGGAAGTTAGATGTCAGAGCCTGTGCTTTTTTTTTGTTTTTGTTTTTGTTTTCAGTAGAAACGGGGGTCTCACTTTGTTGGCCAGGCTGGTCTTGAACTCCTAACCTCAAATAATCCACCCATCTCGGCCTCCTCAAGTGCTGGGATTACAGGTGAGAGCCACTGTGCCTGGCGAAGCCCATGCCTTTAACCACTTCTCTGTATTACATACTAGCTTAACTAGCATTGTACCTGCCACAGTAGATGCTCAGTAAATATTTCTAGTTGAATATCTGTTTTTCAACAAGTACATTTTTTTAACCCTTTTAATTAAGAAAACTTTTATTGATTTATTTTTTGGGGGGAAATTTTTTAGGATCTGATTCTTCTGAAGATACCGTTAATAAGGCAACTTATTGCAGGTGAGTCAAAGAGAACCTTTGTCTATGAAGCTGGTATTTTCCTATTTAGTTAATATTAAGGATTGATGTTTCTCTCTTTTTAAAAATATTTTAACTTTTATTTTAGGTTCAGGGATGTATGTGCAGTTTGTTATATAGGTAAACACACGACTTGGGATTTGGTGTATAGATTTTTTTCATCATCCGGGTACTAAGCATACCCCACAGTTTTTTGTTTGCTTTCTTTCTGAATTTCTCCCTCTTCCCACCTTCCTCCCTCAAGTAGGCTGGTGTTTCTCCAGACTAGAATCATGGTATTGGAAGAAACCTTAGAGATCATCTAGTTTAGTTCTCTCATTTTATAGTGGAGGAAATACCCTTTTTGTTTGTTGGATTTAGTTATTAGCACTGTCCAAAGGAATTTAGGATAACAGTAGAACTCTGCACATGCTTGCTTCTAGCAGATTGTTCTCTAAGTTCCTCATATACAGTAATATTGACACAGCAGTAATTGTGACTGATGAAAATGTTCAAGGACTTCATTTTCAACTCTTTCTTTCCTCTGTTCCTTATTTCCACATATCTCTCAAGCTTTGTCTGTATGTTATATAATAAACTACAAGCAACCCCAACTATGTTACCTACCTTCCTTAGGAATTATTGCTTGACCCAGGTTTTTTTTTTTTTTTTTTTGGAGACGGGGTCTTGCCCTGTTGCCAGGATGGAGTGTAGTGGCGCCATCTCGGCTCACTGCAATCTCCAACTCCCTGGTTCAAGCGATTCTCCTGTCTCAATCTCACGAGTAGCTGGGACTACAGGTATACACCACCACGCCCGGTTAATTGACCATTCCATTTCTTTCTTTCTCTCTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTTGCCCAGGCTGGAGTACAGAGGTGTGATCTCACCTCTCCGCAACGTCTGCCTCCCAGGTTGAAGCCATACTCCTGCCTCAGCCTCTCTAGTAGCTGGGACTACAGGCGCGCGCCACCACACCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCATGACCTCAAGTGGTCCACCCGCCTCAGCCTCCCAAAGTGCTGGAATTACAGGCTTGAGCCACCGTGCCCAGCAACCATTTCATTTCAACTAGAAGTTTCTAAAGGAGAGAGCAGCTTTCACTAACTAAATAAGATTGGTCAGCTTTCTGTAATCGAAAGAGCTAAAATGTTTGATCTTGGTCATTTGACAGTTCTGCATACATGTAACTAGTGTTTCTTATTAGGACTCTGTCTTTTCCCTATAGTGTGGGAGATCAAGAATTGTTACAAATCACCCCTCAAGGAACCAGGGATGAAATCAGTTTGGATTCTGCAAAAAAGGGTAATGGCAAAGTTTGCCAACTTAACAGGCACTGAAAAGAGAGTGGGTAGATACAGTACTGTAATTAGATTATTCTGAAGACCATTTGGGACCTTTACAACCCACAAAATCTCTTGGCAGAGTTAGAGTATCATTCTCTGTCAAATGTCGTGGTATGGTCTGATAGATTTAAATGGTACTAGACTAATGTACCTATAATAAGACCTTCTGTAACTGATTGTTGCCCTTTCGTTTTTTTTTTTGTTTGTTTGTTTGTTTTTTTTTGAGATGGGGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGATGCAATCTTGGCTCACTGCAACCTCCACCTCCAAGGCTCAAGCTATCCTCCCACTTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCATGCCACCACACCCGGTTAATTTTTTGTGGTTTTATAGAGATGGGGTTTCACCATGTTACCGAGGCTGGTCTCAAACTCCTGGACTCAAGCAGTCTGCCCACTTCAGCCTCCCAAAGTGCTGCAGTTACAGGCTTGAGCCACTGTGCCTGGCCTGCCCTTTACTTTTAATTGGTGTATTTGTGTTTCATCTTTTACCTACTGGTTTTTAAATATAGGGAGTGGTAAGTCTGTAGATAGAACAGAGTATTAAGTAGACTTAATGGCCAGTAATCTTTAGAGTACATCAGAACCAGTTTTCTGATGGCCAATCTGCTTTTAATTCACTCTTAGACGTTAGAGAAATAGGTGTGGTTTCTGCATAGGGAAAATTCTGAAATTAAAAATTTAATGGATCCTAAGTGGAAATAATCTAGGTAAATAGGAATTAAATGAAAGAGTATGAGCTACATCTTCAGTATACTTGGTAGTTTATGAGGTTAGTTTCTCTAATATAGCCAGTTGGTTGATTTCCACCTCCAAGGTGTATGAAGTATGTATTTTTTTAATGACAATTCAGTTTTTGAGTACCTTGTTATTTTTGTATATTTTCAGCTGCTTGTGAATTTTCTGAGACGGATGTAACAAATACTGAACATCATCAACCCAGTAATAATGATTTGAACACCACTGAGAAGCGTGCAGCTGAGAGGCATCCAGAAAAGTATCAGGGTAGTTCTGTTTCAAACTTGCATGTGGAGCCATGTGGCACAAATACTCATGCCAGCTCATTACAGCATGAGAACAGCAGTTTATTACTCACTAAAGACAGAATGAATGTAGAAAAGGCTGAATTCTGTAATAAAAGCAAACAGCCTGGCTTAGCAAGGAGCCAACATAACAGATGGGCTGGAAGTAAGGAAACATGTAATGATAGGCGGACTCCCAGCACAGAAAAAAAGGTAGATCTGAATGCTGATCCCCTGTGTGAGAGAAAAGAATGGAATAAGCAGAAACTGCCATGCTCAGAGAATCCTAGAGATACTGAAGATGTTCCTTGGATAACACTAAATAGCAGCATTCAGAAAGTTAATGAGTGGTTTTCCAGAAGTGATGAACTGTTAGGTTCTGATGACTCACATGATGGGGAGTCTGAATCAAATGCCAAAGTAGCTGATGTATTGGACGTTCTAAATGAGGTAGATGAATATTCTGGTTCTTCAGAGAAAATAGACTTACTGGCCAGTGATCCTCATGAGGCTTTAATATGTAAAAGTGAAAGAGTTCACTCCAAATCAGTAGAGAGTAATATTGAAGACAAAATATTTGGGAAAACCTATCGGAAGAAGGCAAGCCTCCCCAACTTAAGCCATGTAACTGAAAATCTAATTATAGGAGCATTTGTTACTGAGCCACAGATAATACAAGAGCGTCCCCTCACAAATAAATTAAAGCGTAAAAGGAGACCTACATCAGGCCTTCATCCTGAGGATTTTATCAAGAAAGCAGATTTGGCAGTTCAAAAGACTCCTGAAATGATAAATCAGGGAACTAACCAAACGGAGCAGAATGGTCAAGTGATGAATATTACTAATAGTGGTCATGAGAATAAAACAAAAGGTGATTCTATTCAGAATGAGAAAAATCCTAACCCAATAGAATCACTCGAAAAAGAATCTGCTTTCAAAACGAAAGCTGAACCTATAAGCAGCAGTATAAGCAATATGGAACTCGAATTAAATATCCACAATTCAAAAGCACCTAAAAAGAATAGGCTGAGGAGGAAGTCTTCTACCAGGCATATTCATGCGCTTGAACTAGTAGTCAGTAGAAATCTAAGCCCACCTAATTGTACTGAATTGCAAATTGATAGTTGTTCTAGCAGTGAAGAGATAAAGAAAAAAAAGTACAACCAAATGCCAGTCAGGCACAGCAGAAACCTACAACTCATGGAAGGTAAAGAACCTGCAACTGGAGCCAAGAAGAGTAACAAGCCAAATGAACAGACAAGTAAAAGACATGACAGCGATACTTTCCCAGAGCTGAAGTTAACAAATGCACCTGGTTCTTTTACTAAGTGTTCAAATACCAGTGAACTTAAAGAATTTGTCAATCCTAGCCTTCCAAGAGAAGAAAAAGAAGAGAAACTAGAAACAGTTAAAGTGTCTAATAATGCTGAAGACCCCAAAGATCTCATGTTAAGTGGAGAAAGGGTTTTGCAAACTGAAAGATCTGTAGAGAGTAGCAGTATTTCATTGGTACCTGGTACTGATTATGGCACTCAGGAAAGTATCTCGTTACTGGAAGTTAGCACTCTAGGGAAGGCAAAAACAGAACCAAATAAATGTGTGAGTCAGTGTGCAGCATTTGAAAACCCCAAGGGACTAATTCATGGTTGTTCCAAAGATAATAGAAATGACACAGAAGGCTTTAAGTATCCATTGGGACATGAAGTTAACCACAGTCGGGAAACAAGCATAGAAATGGAAGAAAGTGAACTTGATGCTCAGTATTTGCAGAATACATTCAAGGTTTCAAAGCGCCAGTCATTTGCTCCGTTTTCAAATCCAGGAAATGCAGAAGAGGAATGTGCAACATTCTCTGCCCACTCTGGGTCCTTAAAGAAACAAAGTCCAAAAGTCACTTTTGAATGTGAACAAAAGGAAGAAAATCAAGGAAAGAATGAGTCTAATATCAAGCCTGTACAGACAGTTAATATCACTGCAGGCTTTCCTGTGGTTGGTCAGAAAGATAAGCCAGTTGATAATGCCAAATGTAGTATCAAAGGAGGCTCTAGGTTTTGTCTATCATCTCAGTTCAGAGGCAACGAAACTGGACTCATTACTCCAAATAAACATGGACTTTTACAAAACCCATATCGTATACCACCACTTTTTCCCATCAAGTCATTTGTTAAAACTAAATGTAAGAAAAATCTGCTAGAGGAAAACTTTGAGGAACATTCAATGTCACCTGAAAGAGAAATGGGAAATGAGAACATTCCAAGTACAGTGAGCACAATTAGCCGTAATAACATTAGAGAAAATGTTTTTAAAGAAGCCAGCTCAAGCAATATTAATGAAGTAGGTTCCAGTACTAATGAAGTGGGCTCCAGTATTAATGAAATAGGTTCCAGTGATGAAAACATTCAAGCAGAACTAGGTAGAAACAGAGGGCCAAAATTGAATGCTATGCTTAGATTAGGGGTTTTGCAACCTGAGGTCTATAAACAAAGTCTTCCTGGAAGTAATTGTAAGCATCCTGAAATAAAAAAGCAAGAATATGAAGAAGTAGTTCAGACTGTTAATACAGATTTCTCTCCATATCTGATTTCAGATAACTTAGAACAGCCTATGGGAAGTAGTCATGCATCTCAGGTTTGTTCTGAGACACCTGATGACCTGTTAGATGATGGTGAAATAAAGGAAGATACTAGTTTTGCTGAAAATGACATTAAGGAAAGTTCTGCTGTTTTTAGCAAAAGCGTCCAGAAAGGAGAGCTTAGCAGGAGTCCTAGCCCTTTCACCCATACACATTTGGCTCAGGGTTACCGAAGAGGGGCCAAGAAATTAGAGTCCTCAGAAGAGAACTTATCTAGTGAGGATGAAGAGCTTCCCTGCTTCCAACACTTGTTATTTGGTAAAGTAAACAATATACCTTCTCAGTCTACTAGGCATAGCACCGTTGCTACCGAGTGTCTGTCTAAGAACACAGAGGAGAATTTATTATCATTGAAGAATAGCTTAAATGACTGCAGTAACCAGGTAATATTGGCAAAGGCATCTCAGGAACATCACCTTAGTGAGGAAACAAAATGTTCTGCTAGCTTGTTTTCTTCACAGTGCAGTGAATTGGAAGACTTGACTGCAAATACAAACACCCAGGATCCTTTCTTGATTGGTTCTTCCAAACAAATGAGGCATCAGTCTGAAAGCCAGGGAGTTGGTCTGAGTGACAAGGAATTGGTTTCAGATGATGAAGAAAGAGGAACGGGCTTGGAAGAAAATAATCAAGAAGAGCAAAGCATGGATTCAAACTTAGGTATTGGAACCAGGTTTTTGTGTTTGCCCCAGTCTATTTATAGAAGTGAGCTAAATGTTTATGCTTTTGGGGAGCACATTTTACAAATTTCCAAGTATAGTTAAAGGAACTGCTTCTTAAACTTGAAACATGTTCCTCCTAAGGTGCTTTTCATAGAAAAAAGTCCTTCACACAGCTAGGACGTCATCTTTGACTGAATGAGCTTTAACATCCTAATTACTGGTGGACTTACTTCTGGTTTCATTTTATAAAAGCAAATCCAGGTGTCCCAAAGCAAGGAATTTAATCATTTTGTGTGACATGAAAGTAAATCCAGTCCTGCCAATGAGAAGAAAAAGACACAGCAAGTTGCAGCGTTTATAGTCTGCTTTTACATCTGAACCTCTGTTTTTGTTATTTAAGGTGAAGCAGCATCTGGGTGTGAGAGTGAAACAAGCGTCTCTGAAGACTGCTCAGGGCTATCCTCTCAGAGTGACATTTTAACCACTCAGGTAAAAAGCGTGTGTGTGTGTGCACATGCGTGTGTGTGGTGTCCTTTGCATTCAGTAGTATGTATCCCACATTCTTAGGTTTGCTGACATCATCTCTTTGAATTAATGGCACAATTGTTTGTGGTTCATTGTCTCCTTAAATTAGACTGTAAGCACCTTGATGGAACTCATACTACCTTTTATTTCACACACACGCACACGCGCACACACAGCCTACACATACACTGCCTAGCTCATTGTAGCATACTAAATACTGATTTTAATGAATAAGCTAAACCTTCGAAACCCATTTGCTAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGATCACCTCAGGTCAGAAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCACATCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGCCAATGCCTTGTAATCCCAGCTATTCTGGAGGCTGAGACAGGAGAATCGCCTGAACCTGGGAGGCGGAGGTTGCACTGAGCTGGGATTGTACCACTGCACTCCAGCCTGGGTGACAAAGTGAGACTCCATCTCAAAAACAAACAAACAAAAACACATCATTTCCCCTATAGCAAAAACATGACGGCACTTACTGTATCAAGAGAGGTGAGAAAAAGGAGCCACAGCAGGATGATTCAAGGGACTCTGCATAGCTCCATTTTAAGAATATGCCTACTGCAGGTCAGAGAAGGTAAGCAAACTGCCTAAGGCCACACAGCCAGGTACAGAACTCTCACCAATATTATTGCCAGCAATCGCAATTTTGGTGTTTATTCTTGGTACCAAGTTGGAGACTATAGGGTTCTCTTCCTAATAGAGACCATCTAGCCTTTCACTGTTTTGTGGATACTTCTTTCTCTTCTTCTTTTTTTTTTTCCCTTTTAAAATCTAGTTATTTTTTTCTTTTTGGTTTCTTTGACACAGGGTCTCTTACTCTGTTACCCAGGCTGGAATGGAGTAGTGCAGTCATGGTTCACTGTAGCTTTGACTTCCTGGGCTCAAGCGATCCTCCTACCTCAGCTTCCCGAGTAGCTGGGACCACAGGCGCCCACCAACACCTCCAGCTAATTTTTAAGTTTTTACTAGAGACAACATCTCACTATGTTGCCCAGGCTGGTCTCAAAATCCTGGGCTCAAGTGATCCCACCTCAGCCTCCCAAAATGCTGGGATTACAGGTGTGTGCAACCACGCCTGGCCTATTTTTTTTTTAATTGCTCATAAATCATCTTTTTTCTTTAAAAAAAAGAAAGATGGGAGGCTAAAGCAGGAGAATCACTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCTGAGATCATGCTGCTGCTCTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAAAAAAAAAAAAAAAGAAAGTACACAATTTTACTTTCTGGACCTAATGGTCAAGGCCAATAATTTGGTCACCTATGAAATAAATAAAAGCTTTACCATATATATGACCATTTGATAATGTAATATGAAATGTTTATGTACTAAAGGCAGAATAGTCTAGAAAAAACATTCTGTATCACAACGTCTAAAAATGAATATCATCTTCATCATAGAACCAGGCTCTTTCTCCTAATTTTTTTTTTTGAGATGGAGTTTTGCTCTGTCACCCAGGCTGGAATGCAGTGGCACAATTTTGGCTCACTGCAACCTTCAGCTCCCAGGTTCAGGATCAAGTGATTTTCGTGCTTCAGCCTTCTAAGTAGCTGGGATTACAGGTGACTGCCACCACACCCAGCTCATTTTTTTGTATTTTTTTAGTAGAGAGAGGGTTTCACCATGTTGGCCAGGCTCGTCTCGAACTCCTGACCTCAAATAATCCACCCGTCTCAGCCTCCCAAAGTGCTGAGATTACAGGCGTGAGCCACCAGGCCTGGCCTCCTAATTTTTATTTGTAGAAGTGGCACCAAAATTTTCCAAGTTCTCATGCAAAAATTCAGGCTCATCTCAGTTTATTTTTTTCATTTATTTATCTCCCACTAAATTGACAACTTCTAATAATTAGGTTGGTTCTTTGTATTCCCAGCACAGGGTTCTATGCAGAATACACACACAGCAGTTGCTGGCAATAATATTGGTGAGAGTTCTGTACTGGGCTATGTGATCTTAGACAGTTTGCTTATGTTCTCTGACCTGCCGTAGGCACATTCTTAAAATGAAGCTGTTCAGACCCCCTCGATTCATCCTGCTGTGGCTTCTTTTTCCCACCTAAATCTTAAATACCCTTTTAGCTGCTAGTAAGTGAATGATGTTTTTTTATGAACTTTCTGAAGTCAGATTAGATGAAGTTGAGAAAAGCCTGATATTCTTATAAAGTTATATATGTGCATCATAGAAAACTTAGAAAATACAGATAAACAAAAATCATCCATGGACGAACCTTGAAGACATTGTGTTAACTGAAATAAACCGGACACCAAAGGACACATGTTATATGCTTCCACTTATATGAGATACCTAGAATAGTTACATTTGGTTACTCTGGGTACATTGCCTATAGATAAGCCTTGCTCCACAAGGAGCAGTTAAAAAAAAAAAAAAGATAAATTCATAGGATGGAAGGTAGAATAGTGGTTACTAGGGACTTGGGGAGGGGGAAATGGGGAGTTACTGTTTGATGAGTGCAGATTTCAGTTTGGGATGATGAAAAAGTTCTGGAGATAGATAGTGGCAATGGTAACACAACAGTGTGAAAATAATGCCACTGAACTGTACACTTAAAATGATTAAAATGATAAGTTAATTGTAATTTGTGTTATCCAGAAATGGTTAGCAATTTATTGGTGTATATTCTTTTAGTATTCCTGTGTGTGCACAGGGGTGCTTGTATATACTTTATCTTTAAAATATATCCAGGAAGCTAGGCACAGTGGCTTACACCTGTAATCCCAGCACTTTGGGAGGGTGAGGCAGGAAGATTGCCTGAGCCCCGGAGGTCAAGGCTGCAGTGAGTTGTGATCACGCTACTGCACTCTGTTCTGGGCAACCCCTGTCTGGGAAAAAAAAAAAAATTAGTGAGGCTTAGTGGTGCACACCTGTAGTCTCAGCTACTTGAGTGGCTGGGGTAGGATTGCTTGATCCCAGCAAGTTGAGGCCGTGGTGAGCCATGATGGTGCCACTGCACTCCATCCTGGGTGATATGGTGAGACCCTGTCTCAAAAACAAGAAATCCAGATAATTCTGTGCATTATAATCTAGCTTTTACTGGATCATTAAAATTCTTTTTTCTTTTTTTTTTTTTTTTTCTGAGATGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAGTGGTGTGACCTTGGCTCACCGCATCCTCTGCCTCCCGGGTTCATGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGTGCCACCATGCCCAGCTAACTTTGTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGACCAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGGTTACAGGCGTGAGCCACCGCACTCAGCCTGGGTCGTTAAAATTCTTAAGTGACTTCATTTTTAATTACTATATGGGATTCTATCTTTCCAGTGTATCATGATTTATTTGACCTATTGCTGAATGTTGGAGGTTTCAGGGTAAGAGGCACAGTTTGCTATTATGTACATCACTATAGTGGCATCCTGATAGCTAAATATTTGCCTACATCCCTGATTATTTCCTTAGTCTAAATTACTGGGACTAGGATTTTGGTGTTTGATACATGTTACTAAATTGTTTTTTAGAAAGATTAAACCAGTTTATGCTCTTCCAGCCCCTGTGGTATATGATAGTTCCCATTTTCCTGTACCTTGCCAACACTGGGTGATATCCAGTTTTAAAATCTAAATCTTGCATTGCTATGAGAACTACAATTAGAGAAGGCTTATCTTCTACTGCCCATTCTCTGTACAGAGCAAATCCCTCTAGACCTGAAGCCCCTTGGAGTTGTCAAGAAACCTTTGAGATGACTCCCCACTCTGTATCTGAGCTGTCACCAGTATTCTCCACTTCTTCAGGATTGCCATGGCAACTAAATTGATGAAAAGATTTAGGAGGCCTTTTCTCTCTTTGCAATTCCTATGATCCTTTTTGAATGTGGGTTTGGGACTCTGTCAATATACCCATCATCTAATTCTGTCCATTGTGTTTTAAAGTTTAAGGTTGCAATTTCTGATTACATCTGCCTTAGCCATACTGTATTATATTTGACATTCAATATACAATGTCCTTGTTTTTCTGTATTTCTAATCTTATTCCCAGAGATGTGTCTATTTGTTCAGGATTCATTTTGCAACGTGTTTTTACTAAGCATCTACCCAAAACCGTTGAAGTCAGATTTCAGGCTGTCTTACGTCTAAAGTAGCACAGGCAGGAAAAACTATTGAAGTGGGATTTTTTTTTCCCTTTTTGTACTGAACCGAGAAAAAGTATATAGATGATAGAGAATTCCTAATTTGGTATCATTGATATCTGGGTTTTTGTTTGTTTTTACAGAAGACTGATTAACTATACTTATTTATTAATTTATCTTCTCATTAATAAACACTTGCTGAGTGCTTACTGTCTGCTAGGCATTAGGGAGACAAATATGATTAAGGGAAGCTTCCTCCTATCAAGGTCATGTGTTCCATTTGGGTATACTAATGCATTAGCAATGTAAATCAAGTAGTGAGAGATCATCTGTTCCCGATAGGAGATGGATTATTGGTGGGGACTTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTATGTGATAAAATAAATATAGGAAATGTTAATTATAGATTCTAAGTAGTAGATATATAAACACTCATTGCAAAGTTGCTTCAAGTTTTCTGTATATTTGAAAATATTCACAACATGTCGACAAAACTAGCATGATAAAGCCACTATTTGTGCTAAGACTTCAGCTTGTATCTGGATTAGGCTTATTATGTAGTAGTAGGAACATTAGAAATAGTTTTAACTCATTAAATACACATGTTTTATGGGAAGGTTTTATATATATATTTATATGTAATGAATGTGAACAAACAAGGGTCAGATATACACTCTGCTTCCCTCCAGACCAGTTCCGGCTGCTCTGCTGCACATTTCAGGAGTCTTATTAGAATTAGCCACATTCTGCCCACTTGCCCTTACTTCTCATATTTCACAACTCCTCCTGGTGGGGACTTAAGGAGACATTCAAACTAGGCCTTGAAAGATGAGAATTTTTCCAAGTGGAAAAAGAGGAGTGGCAGCAAGTAAGGTAAAGGTACAGAGTCATGGAATTCCCAGGAAACGTAAAGTTGTCATGTGTTATAGGAAAACAACTTGTGTGAGGGGTGTTGGGAGAAATGAGAGATAATACCAGGGTATAAAGGGCCTTTTGAATGCTATGTTGAGGAATTTTATCCTAATGGCAGTAATGACTAACAATTATATAGTGTTCAAAAAGTATAAATCAGCAGTGGTATACCACTAAGGGTTTTTTTCTTTTCTTTTTTTTTTTGAGACAGAGTTTTGCTCTGTTGCCCAGGCTGGAGTGCCGTGGCACGATCTCAGCTCACTGCACTTCCGCCACCTGGGTTCAAGTGATTCTTCTGCCTCAGCCAGTGTTTCACTGTGATGGCCAGGATGGAGCACTAAGGGTCTTTATGGAAGAAAAAGACATGATAAACAAGGCTTTTAGGGAACTTCTACAGTAATGTAGCTGTATTAAAAGTAGAGATCAGAGCAGCATAGTAGAAGTAGAAGGCTAGAGCTAATTGAAGGAGCACTTCAGAATTAGAATCAAGAAGTCTTAGAAACCTATTGGTTTTATTCTCCCTAATGTATTTGGCCACTTACCTGCTGGGGAATTTGTCTAAGTTATAAAAAATAATTCCTTTGGGAAACCCAAAGGAAAGTTATCTATTAATAATTACCCCACTACTTTTTCTGATTTATGTAATGGCCACGTAGAGGTTAGATGTGATGGTTGTGACAGTAGTGACTAATACAGCCTGTGAAGCATTTTGGTCAGATATCTATGTGCTTTCATTCCAGGTTGACTGAGGCAAGACTTTGGCTAGGGTTTGATCAGTGATGTAACTACTCACGAGTACCACGTGGTGGCAATGGCATTGCTGCAGACCTTGGCAGCAAAGCAGTGTTAGAGTAGCAGTAGAAACCTTTGTGAAGCTAGGAATACATTTTCTGGTCATAAAAACCTCCTGAAAATTGTGAACTCAGTGTAGCAGGAGAAAGAAGATGGCTTGTTTTTAGTAAAGGGCAAAGTCATTTTTAAGGATCAGAAGAAGAAACGGAGAGTGAAACAATGTGTTCCTGCCCTACTCCCCCACTGGACTTTTTGGCAACCATTGCTGTTCCTTCTAAAAGTGATTTTTAAACATGTATATTTTGAAGCCAGGCACAGTGACTCACGTCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGGCCAGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGAGGATCATGTGGTCAGGAGATCCAGACCATCCTGGCTAACACGGTGAAACACCATTTCTACTAAAAATACAAAAAATTAGCTGGGCATGGTGGCGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAAGCAGAAGAATGGCTTGAACCTGGGAGGCGGAGCTTGCAGTGAACCAAGATTGCGCCACTGCACTCCAGCCTGGGCAACAAAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAAATTAGTCGGGCATGGTAACAGGTGCCTGTAATCCCAGCTACTTGAGAGGCTGAGGCAGGGAGAATTGCTTGAACCAGGTAGGCGGAGGTTGCAGTGAGCCAAGATCGCACCACTGCACTCCAGCCTGGGGCAACAGAGCAAGACTGTCTCAAAAAAAATAAATAAATAAAATAAATTCTTAAGAAGGATATTTTGGAAAACTCCTTACATACCTAAATTCTTTGTTTATCAAATACTTGGACTTAGCACACTCTTCTTTGAAATGGACCAATAAACAACAGGAGCCCATAAGCAAAAAGAACTCATTATTTTAAAAACAGTAACTATCCTTACAGGCTTTCTCAGGGCTCTTTCTGTTGGATCCTTCCCTCTCACAGGTCCTTGCTAATGATCTCTAGGTGGACACATTCTAGATGAGATGTCCCTGTCTAGAATGGCAGCACCATGAGGGCTATATCCTCAGTACTAGGACAGCGCCTGGTGCTTAATAGATAGTAAATAGTTGTCTAATTAACTGAGCAAACAGATAGATTCATGAATTAGCTTTTTGCTTTTTCTGTTAGAAACTAAAGGTTCAGGTCAGGCACAATGGCGCATGTCTCTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCTGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATAGTAAAACCCTGTTTCTACAAAAATTACCAAAATTAGCCGGGCGTCTTGGCAAGCACCTGTAATGCCAGCTACTTGAGAGGCTGAGGTGGGAGAATCGCTTGAACCTGGGAGGAAGAGGTTGCAGTGAGCCGAGATGGTGCCAACCTGGGTGACAGAGGGAGACTTAAAAAAAAAAAGAAAGAAAGAAAGAAAAGAAACTAAAGGTTCAAAGAATCCCAGAAAAGGAAGAGTCCTCACAAGCCAGTAATCTAGGCAGGATTACTGATAGTATTTTTATATTTGTTGTATTTTTATAAAATGCCATAGATAGAGGGCTTTTTTCAACATTACATCAGTCTAAAAATCACACATTTTTATATGAACTAACCTAAATGTCTGATGAATCTCACAACACCAAGTCTTTGAAATGTGCCCATATAAATAAAATGTTAACAGATTCATGCTAATTTTAAATATCGATAGTGTTTAAATGCCTTAATTATTTTTTCACTCCCTAGCTTTAAAAGAAAATAACCAACTTCAAAAGGACATCACAATAACATCAAGTCTATTTGGGGGAATTTGAGGATTTTTTCCCTCACTAACATCATTTGGAAATAATTTCATGGGCATTAATTGCATGAATGTGGTTAGATTAAAAGGTGTTCAGCTAGAACTTGTAGTTCCATACTAGGTGATTTCAATTCCTGTGCTAAAATTAATTTGTATGATATATTTTCATTTAATGGAAAGCTTCTCAAAGTATTTCATTTTCTTGGTGCCATTTATCGTTTTTGAAGCAGAGGGATACCATGCAACATAACCTGATAAAGCTCCAGCAGGAAATGGCTGAACTAGAAGCTGTGTTAGAACAGCATGGGAGCCAGCCTTCTAACAGCTACCCTTCCATCATAAGTGACTCTTCTGCCCTTGAGGACCTGCGAAATCCAGAACAAAGCACATCAGAAAAAGGTGTGTATTGTTGGCCAAACACTGATATCTTAAGCAAAATTCTTTCCTTCCCCTTTATCTCCTTCTGAAGAGTAAGGACCTAGCTCCAACATTTTATGATCCTTGCTCAGCACATGGGTAATTATGGAGCCTTGGTTCTTGTCCCTGCTCACAACTAATATACCAGTCAGAGGGACCCAAGGCAGTCATTCATGTTGTCATCTGAGTACCTACAACAAGTAGATGCTATGGGGAGCCCATGGAAGATACATGGTATACAACATAGCTCTTGCTCTATTGGAAGCTAAGTGGAATGGGAGAAATTGGTGACAGGCAACCCCATAATTTCAGAAAGCTATGAAAAAGTACTCAGACATATTCCTTATAACACTGGTGTCACATCACAAAGACCTATTTAATGTGCTTCTGATTTATAGGGAGAGACATCCTATACTTCAGGAACTGCACTTTGATCCACAGAAAGCCTAGTGATGTAGAGCTCCTGTTAGTTCAAAAGGAAAAGAAAAGAACAACACAGAAAGCCTAATTATGCAATAGAGTCAAGTGCTTTATAGCAATGTTACAGTTATCAAAAAAAATCCAGATGGACCTCTGAGAGGATGCCATTGGAGTAACCAGGCAGATGCAGTTGATCAGAGCTGACTTCCTATAAGAAGTGAGCACTGAGCTGAGGAATAATGGCATAAATGAAGGAAAGTGAGATGGAAATTTGAGTTTTTAATTGGAAAGACAATACATCAGGCAGATTTTTAAATAGGGGCAAACAAACAGACACATAGGAGATGCTAGGCATGGGGTCCCCACTAGGATGCTGCTTAGAAACATGCAGGGGTGGTGAGTACTCCCAAAGTACACTTCATTCCTAGCTCAGTGATTCTTATCTGAGTGTTAAAGTTCCTTCTTCAGCACCCCGTTCCACAGTCCAACTGGGAACTTTAAGACCTTTCTTGGAGTCTTTCTAGGAACTCAAGTCTGCTACTTATACAGAACAGTGGCTTTGGTCCCCAGTTGTGCCTTGCAGTATTTTTGTGTTCAGGAAGAAACAGTAGCTCTTGGATAAAGAAGCTAGCTAGAAACTCTGTTGCTATGGCAGTGCTTCAAAATGTATTTCCTTAAATGCTTTCTTTGTAACTATCTTCATTTAGTTCATCTCTCAGATAATGAGAGATCAGAGTCCCATCCCCAGTATAATACTCTTCTTTAGGGTACTTTCACCATCTTCAGTCTAAACACAGACTAGACTTTCAATTATAATGTGTAAGATTTAAAATGTTATTATTGTGTGACTTTGAATATCTGTGTAAATCTACTATCTCCTCTTTGGTATATACGTGTGTTTATTTTTTTCTGGAGATCTGTAACTGAAATGCTTAATTTCTGAATTGTTTTGGATATCACAACTTAATACCAACATAAGTTTTGAGCCTTTTTCTCCCTAAATCTGGTGTGAGTCTAACTGAAACTCAAATGAACTTTTTAAAAATAATTTTTTCTTTTCTTTAATTTTTTTTTTAAGTAGAGACAGGGACGCACTGTTAACTAGGCTGGTCTTGAACTCCTGATCTTGAGCCATCCTCCCCGACCTGAGCCTCACCTTATAGAGAGGGTCTTGCTCTGTTGCCCAAGCTGGAGGGCAGTGGCATAATCACAGCTCACTGCAGCCTCTCGACCTCCTCAAGCGATCCTCCTGCCTTAGCCTCCCAAGTAGCTGGGACTATAGGCGTCCACCACCATACCCAGCTAATTTTTTTTTTTATTTTTTGTAGAGACAAGGTCTCCCTATGTTGCCCAAGTTGGTCTCAAACTCCTGGACTCAAGCAGTCCTCTCACCTCAGCCTCCCAAAGTGCTGGGGTTACAGGTGTGAGCCATGGCACCTGGCCAGAACTTCTAGTAAAAAGAATATTGTTGCCGGGTACGGTGGCTCACGCCTGTAACCCCAGCACTTTGGGAGGCCAAGGCAGGCGAATCACCTGAGGTCGGGAGCTCGAGACCAGCCTGACCAACATGGAGAAACCACATCTCTACTAAAACTACAAAAAATTAGCCGGGCGTGGTGGCACATGCCTGTAATCCCACCTACTTGGGAGCTACGGTGCCTGGCCTAGTTTATTATTTCTTAATATCTGTTGTCTTCCAGTGTCTTCCTTAATTCTTCACAATACCCTGTACAATGCTTAGCACACAGTGGGCAGTCTGTAAGTTTATTAAATGTTTGGTGTGGCCCATACTTCCTATCCACAAAGAATGTAACATGTTAAGACATCTAGATGAGGGAATGATTTAAGAGGAACTACAATAATATTCTGAAACTTGGACTCTGGATCTCTGCATTTAGACTTTCCTAAACCAGCCAGCAAGTAGATCATCATGTCACAAGGCTTAGGTTGGGCTTGCTGTTCAGAGAATGAATTAAGGATTAAGGAGAAAAAAAAGCAGAAAGGTTTTGCTCTGTTTTTCAGGTTCTATTGAGTTGTTAACTTCTAACAAGTTATCTTATTTGCTTCATTGCATGAGGCCCATTGTAGTAAGAAGAGGAATTTATATGCTAAATGTTCTGGTGATAGAATGACTTTTCTTTTTTTTTACAGTCCAAAGGTCTTTTTTTTTTTTTTTTAACACCTATTATGCCATGAATTCATAGGGAATAGGTTCCAGCTGCTCAGGCTCCTTCCCATTGGTTCTCACAAAGTGTGCTTCTCTGGGTGGAGCAGGCTGGTGCTTCAGTTGAACCCACGTACCTTTCTCTTTGGCTTCTTTCTTTTTCTGATCATTTTCCTTCACGCGTTTCAGGAAGCTGTCTTGGCTCTTAGAGTGTTTAATGTGCTCAATACGCACATTAATTCTCTTGGCAAGAATCTTGCCCTTAACTTGTTTACAGCGATGCCAACAGCATGCTGGGTCACGTTGTAGACTTTTCCAGTTTTGCCATGGTAACACTTGTGGGGCATTCCTTTTTGAACAGTACCCGTTCCCTTGATGTCTACAATTTCACCTTTCTTACAGATTCGCATATACATGGCCAAAGGAACAACTCCATGTTTTCTAAAAGGCCTAGAGAACATATATCAGGTGCCTCTCCTCTTTCCCTTTGTGTTCGTCATTTTGGCAAATTACTGAAAGATGGTGGTTCTGGCCAAAAGGAGGAATGACTTTTTAATAGCTGTGTTTGTATCTGAGCCTTCCCTCTGCCTTTCATTTTTTTTGTTTTGTTTTGTTTTGTTTTTGTTTGAGATGAAGTTTCACTTTTGTTGCCCAGGCTGGAGTGCAATGGTGTGATTTCGGCTCATTACAATGTCCGCCTCAGCCTCCTGGGTAGCTGGGATTACAGGCACCCGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCGGGCTGGTCTCAAACTCCTGACCTCAGGTGATCTGTCCACCTCGGCCTCTCAAAGTGCTGGGATTGTAGGCGTGAGCCACATCACCTGGCCACTTTTTTAACTCTTTCCAATGGTTAATTCCGTTTGATATGGTTCCTTGGAACTTGCACATTACCCTTTATCAATTATCACCCTGTATTGGGGGTGGGGAGGATGATACCTCTCTTCATAGTTAGATCCTACTTACTTTCAACAGAGTTCTTAACAATCCTAGAAACTCACAGGTCCAGAAAAGACAAGCATAAAGGAAACTATAAATAATGCATTTGAAGACTAACTCAGGAAATCAATGATTATTTCCCCCCAGGCTACCCAGTGTCTTAAAAAAACAGTTTAATTAATACAATCTTTTGTTTCAATTTTCTACCTATATTTATGGCTTTTAGCTTTTCTAATAAAAGCTCAAAATGAATTACAGTCATCAGTGACTTTTTAATGAATAGAAGACTTTTGCAATTTTTAACTATTTGTTTTTACTTATTAAATATTTCCGCCTTGGCCAGGCATGGTGGCTCACGCCTATAATCCCAGCACTGTGAGATGCCAAGGCAGGAGGATCACTTGAGTTTAAGAGTTCTAGACCAGGCTGGGTATGGTGGCTCATGCCTATAATCCCAGCACTTTGTGAGGCCAAGGTTGGCGGATCACCTGAGGTCAGGAGTTTAAGACCAGCCTGGCCAACATGGTAAAACCCCATCTCTACAAAAAATACAAAAATTAGCCAAGGGGTGGTGGTGGGCACCTATAATCCCATCTTCTTGGGAGGCTAAGGCAGGAGAATCGCTTGAACCTGGAGGCAGAGGTTGCAGTGAGCCGAGATCATGCCACTGTATTCCAGCCTGGGTAACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAGTTTGAAACCAGCCTGGTCAACACAGCAAGACACCCATCTCGTTGAAAAATAACGGTCGGGCGCAGTGGCTCACGCCTGTAATCCCATCACTTTGGGAGGCCGAGGCAGGCAGATCACCTGAGGTCGGGAGTTCGAGACCAGCGTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGTTGGGCGAGGTGGTGCATACCTGTAATCCCAACTACTTGGGAGGCTGAGGCAGGAGAACAGCTTGAACCTGGGAGGCAGAGAGGTTGTGGTGAGCCAAGATCATGCCATTGCACTGCAGCCTGGGCAACAAGAGCAAACTCCATCTCAAAAAAAATAAATAAATAAAAATAAATAAATAAGTACTTCTGCCTTTAAGCCACTTCCTAGAAGGCAGTGGCACAAAGTGATACATTTGGAGGAGTAAATATATTACAAAATGAATTAGGCTGGGCGCAGTGGCTCATGTCTGTAATCCCCGCACTTTGGGAGGCCAAGGCGGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGATCAACAGGGTAAAATCCCATCTCTACTAAAAATACCAAAAAAACTAGCTGGGCGTGGTGGCAGGCACCTGTAATGTCAGCTACTAGGAAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTGCACCATTGCACTTCAGCTTGGGCAACAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAGAACTAACATGCCAGAACTTTGCCTTCAGTATGTTTTGTGATTTTTCCCTTCTTGTGCCATTTCATCATTAGTTCCATGTATTATTTAAGATTTCTTATCAACCAGCACCTTGGGATTTTTTTGTGTATGTGTTGGTTTAGGGGGTTTATTTGTTTTTTTCTTTTTTTTCGGTAATTGAAAATGTGAAGCAAAATGTCACCTGTTTTTTCTTTCATGTCTGACACTCATGTCTTGTTTACCCCCGACATGCAGAAGCTGAAATCCCCATTTCATACAGTCTTCAATGTGGAGGCAGTAGGGATGGAGAAAATAATGTACTTTGTGCTCTCCGGTACTCTTTCTTTCCTATTGTCTGAGGGGATTTGGGCATAATTTATTTTGCTGCAGAGATAAAAATTTGTTATATATATTTTTTATCATTCAGGGCCAAGGAATATAGATTTTTTTTTTCAGCCTTGTCTCAGCTGGGTGTCTTTATTTACTCTGTCTTAAAGTGTTCCTTTTATTATCATTATTATTTTTTAATCATTGAATTCCATTTGGTGCTAGCATCTGTCTGTTGCATTGCTTGTGTTTATAAAATTCTGCCTGATATACTTGTTTAAAAACCAATTTGTGTATCATAGATTGATGCTTTTGAAAAAAATCAGTATTCTAACCTGAATTATCACTATCAGAACAAAGCAGTAAAGTAGATTTGTTTTCTCATTCCATTTAAAGCAGTATTAACTTCACAGAAAAGTAGTGAATACCCTATAAGCCAGAATCCAGAAGGCCTTTCTGCTGACAAGTTTGAGGTGTCTGCAGATAGTTCTACCAGTAAAAATAAAGAACCAGGAGTGGAAAGGTAAGAAACATCAATGTAAAGATGCTGTGGTATCTGACATCTTTATTTATATTGAACTCTGATTGTTAATTTTTTTCACCATACTTTCTCCAGTTTTTTGCATACAGGCATTTATACACTTTTATTGCTCTAGGATACTTCTTTTGTTTAATCCTATATAGGTTTTTTGAACCTATAACATAAGCTACAACATGAGAAATGTGCGGTTAGATAGATATGTCCCTTCTGAAGGTCAGAAAAAAATATAATGGAGGTAAAACCTGAACAAGCTTGGAAACTGATGGTAGACTTCTTCAAGGCAGCCCTTGCCCTAATTAAAATTCTTGTCTTTCTAGAAAAAGTCTAGCTGTTGATTTACCACAGAAAATAATAATAATAATTACTATTATTATTATTTTTTGAGACAGGGTCGCCCTGTGTCACCTAGATTGCAGTGGTGCAGTCATGGCTCACTGCATCCTCCGTTTTTCAGGCTCAAGCAATCCTCCCACCTTAGCCTCCTGAGTAGCTGGGTCCACAAGCATGCGCCACCCACACCCACTAAGTTTTTGTATTTTTGGTAGAGATGGAGTTTTACCTTGTTGCCCAGGCTGGTCTCAAATTCCTGGACTCAAGTAGTCCGCCCGCCTTGCCCTCCCAAAGCCAGAAAACATTTAGAATATCTTTCAGAGATGTGTATTTACACCACTATTAACACAGGGCTGTATAGCAGTCCAGTACTGGACTATGTAGTCCAGTACTATTCTTTTCCTTACTGGAGGGCCAGGCGTGGTGGCAGGTGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCTGGGACCGTGCCATTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAACAAAAAAAAAAAGAGAGAGAGAGCAGTAATTCAGGTCTCACCCATCTTCAATCCAGGGGGCCTAGCCTTAGTATTTGACCCATAGTAAGCACCCAATAATTGTTTAAATTAATTAACCTCTGAGGCCCTTTAAATCTGTTGATAAGTATCTTATTTTGCAAAGTCCTAAGCACTTGGAAGAGCAGAGGAACTATTTACTGGGTGTGTATGCTTTTCTAACAATATTTTATAGCTGGCTTTTGTTTTTAGAATGAATTTGAACATTGAAAAGGCAGGCAATAGGGATGATTCTGTGAATTCTGCTAAAACTGAGTAGAAAGAATGAGTGTAGAGATGTCGACATTGATCAACTTTCTATCTTCATAAGAGATCTGATTCTAACATATCCATTTAGACTCAAGTAGAATATTGTGTATAGAGTGAGTGGCAGTGAGTAATTTGGTAAAAATTTGCTGACCTGCTTTTATTCTTTCCTCCTTTCTTTCTTCCTTTCCTTCCTTCCTTCCTTCCGTCCTTTCCTTTCCTTTCCCTCCCTTCCTTCCTTCTTTCCTTCTTTCTTTCCTTTCTTTCCTTTCTTCCTTTCTTTCCTTCCTCCCTTCCTTTTCTTTTCTTTCTTTCCTTTCCTTTTCTTTCCTTTCTTTCCTTTCCTTTCTTTCTTGACAGAGTCTTGCTCTGTCACTCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCTGTCTCCCAGGTTCAAGCAATTTTCCTGCCTCAGCCTCCCGAGTAGCTGAGATTACAGGCGCCAGCCACCACACCCAGCTACTGACCTGCTTTTAAACAGCTGGGAGATATGGTGCCTCAGACCAACCCAACCCCATGTTATATGTCAACCCTGACATATTGGCAGGCAACATGAATCCAGACTTCTAGGCTGTCTTGCGGGCTCTTTTTTGCCAGTCATTTCTGATCTCTCTGACATGAGCTGTTTCATTTATGCTTTGGCTGCCCAGCAAGTATGATTTGTCCTTTCACAATTGGTGGCGATGGTTTTCTCCTTCCATTTATCTTTCTAGGTCATCCCCTTCTAAATGCCCATCATTAGATGATAGGTGGTACATGCACAGTTGCTCTGGGAGTCTTCAGAATAGAAACTACCCATCTCAAGAGGAGCTCATTAAGGTTGTTGATGTGGAGGAGCAACAGCTGGAAGAGTCTGGGCCACACGATTTGACGGAAACATCTTACTTGCCAAGGCAAGATCTAGGTAATATTTCATCTGCTGTATTGGAACAAACACTTTGATTTTACTCTGAATCCTACATAAAGATATTCTGGTTAACCAACTTTTAGATGTACTAGTCTATCATGGACACTTTTGTTATACTTAATTAAGCCCACTTTAGAAAAATAGCTCAAGTGTTAATCAAGGTTTACTTGAAAATTATTGAAACTGTTAATCCATCTATATTTTAATTAATGGTTTAACTAATGATTTTGAGGATGAGGGAGTCTTGGTGTACTCTAAATGTATTATTTCAGGCCAGGCATAGTGGCTCACGCCTGTAATCCCAGTACTCCAGGAGGCCGAGGCAGGTGGATCAGCTGAGGTCAGGAGTTCAAGACCTGTCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAAATTAACTGGGTGTGCTAGTGCATGCCCGTAATCCTAGCTACTCTGGAGGCTGAGGCAGCAGAATCACTTGAACCCGGGAGGCGGAGGTTGCGGTGAGCCAAGATCACACCACTGCACTCCAGTCTGGGTGACAGAGCAAGACTCCATCTCAAAAAATATATATATATATATATACACACATATATTTTATTTCAACTGTTAGACAAGAGTCCAAAGGCCAAAGAATAAAGTTTTAGGCCAGTCCTTTATTAGAAAATGAGTCAAATCCCAAAGCAAGTTTTTTTTATGAGTTAATGAATATAAATGACTACATATTTTATGCCTTAAAAATCACTTTTAATGAATGGTGTTTTATGGCTTGTAAATCAGAGTTTTAATCAGTAAAGAAAGTTTTTAATCCTCAAAAACACGTTATCATAAAAGACACTGTTTGGCATCAAATGTGGTATTTGGCCATGTTCATTAGGGTCATTTTAGGAATCTCATACATTCTACTTAGCTATGCTTAATTCCTGATACCATGGCATTTTCTGAAATGTTTCAAGGATGACATCTCTGCTGTTTTTAATTTGGTAATGATATCTGCTGATTTATTAAGTGAAAAAAGTAATGGTGTCATTACCTTGGATGAAGAAACAAAAATAAAGCATTTGCCACATTTTTCAACTTTTTTTTCCTTTCTTACAAAATTGCTATAAGCTCATTGCCCCCAAATTGGACAATATAGGGAATAAAAAAGATAATTTGGGGTGGGGTTAGACACGGGTCTTGTTATGTTGCCGAGGCTGGTCTCTAACTCCTGGCCTCATGCAATCTTCCTACCTTGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACTTCACCAAGCTGAGATGCCACCTCTTAAAAGATAAAATAAGGACAGATTACAGCCACTGCTCATGCCTGTAATCTCAGTACTTTGGGAGGCCAAGGTGGGAGAATTGCTCGAGGCCAAGAGTTCAAGACCAGCCTGGGCAATGTAGCGAGACCTGATCTCTATAAAAAGTAAAAAAAAAAAAAAACTAGCTGGGGCCAGGCGTGGTGGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACCTGAGGGCAGGAGTTCAGGACCAACCTGACCAATATGGAGAAACCCTGTCTCTACTAAAAATACAAAATTAGCCAGGCTTGGTGGCTTATGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTTCAGTGAGCTGAGATCGCGCCATTGCACTCTAGCCTGGGCAACAAGAATGAAACTCCATCTCAAAAAAAAAAAAAATCAGCTGGAAGGTGGCAAACACCTGTGGTCCCAGCTACTCAGGAGGCTGAGACAGGAAGATCACTTGAGTCCAGGAGGTCAAGGCTGCAGGTGAGCCATGTTTGTGCCACTGCACTGCAGCCTGGATGACAGACCGAGACCCTTCTCAAAAAAAAAAATATTACCCGTACTCTTTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGCAATCTCGGCTCAGCGCAACCTCCGCCTCCTGGGTTCGAGCGATTCTCCTGCTTCAGCCTCCCCAGTAGCTGGGATTACAGGCATGCACCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGTCAGACTGGTCTCGACCTCTTGACCTCAGGTGATCCGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCCTGAGCCACCGCACCCGGCCTGTACTCTTATTCTTTAATAATAAAATATTTCTGTGTTTCTTTAGTCATTTTACATAAACTTTTATTTATTTATTTATTTTTATTTATTTATTTTTTTGAGACGGAGTCTCGCTCTGTTGCCCAGGCTGGAATGCAATGGCTCAATCTCAGCTCACTGCAAGCTCTGCCTCCCGGGTACACGCCATTCCCCTGCCTCAGCCTCCCTAGTAGCCGGGACTACAGGCGCCCGCCACCACGCCCAGCTAATTTTTTTTTTTGTATTTTCAGTAGAGACAGGGTTTCACTGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCGTGATCCACCCGTCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGTGCTCGGCCCATAAACTTTTATTTTTAAAATAATGTCATGATAAATAATATTGCTTAGGTGTCTTTAATATATTAGTAACATTTCTGTTTTATTGTACATCAACATTTATATTCAAATTAATGGGTGAAGAGTACTCCATTGGACTAGGTATATCGTAATTTAATCTCCTATTATTGGACAACTACATTGTTTCTAAAATTATACTATTCCTATGACTAAACCTTTGCATATATCTTTTATCTCCCTAGGATATATTTCTAAAACTAGCATTGTTGACTGAAAGTGTAAATACGTGTTAAGGTGTTTGCTACATAATGCCATATTTCCTTTTTAGGAAACTAAGCTACTTTGGATTTCCACCAACACTGTATTCATGTACCCATTTTTCTCTTAACCTAACTTTATTGGTCTTTTTAATTCTTAACAGAGACCAGAACTTTGTAATTCAACATTCATCGTTGTGTAAATTAAACTTCTCCCATTCCTTTCAGAGGGAACCCCTTACCTGGAATCTGGAATCAGCCTCTTCTCTGATGACCCTGAATCTGATCCTTCTGAAGACAGAGCCCCAGAGTCAGCTCGTGTTGGCAACATACCATCTTCAACCTCTGCATTGAAAGTTCCCCAATTGAAAGTTGCAGAATCTGCCCAGAGTCCAGCTGCTGCTCATACTACTGATACTGCTGGGTATAATGCAATGGAAGAAAGTGTGAGCAGGGAGAAGCCAGAATTGACAGCTTCAACAGAAAGGGTCAACAAAAGAATGTCCATGGTGGTGTCTGGCCTGACCCCAGAAGAATTTGTGAGTGTATCCATATGTATCTCCCTAATGACTAAGACTTAACAACATTCTGGAAAGAGTTTTATGTAGGTATTGTCAATTAATAACCTAGAGGAAGAAATCTAGAAAACAATCACAGTTCTGTGTAATTTAATTTCGATTACTAATTTCTGAAAATTTAGATCTAGATAAAGCTATAGTGTGGATTATTTTATGTATATTTACTTGAGAAAATAATTATTAAATATTAGTGGAAAAGCTATACTTTGGGTATGATATAGGACTTTCGAATTGGAATTTTCCTTTCTATCTGTAAAAGCAAGTAGGTATAGTTTTATTCCCCAGAAGGCATCTTTTTCTCCCCCTTGTCTCACATGGGTGAATTTACCAGCATATTTAACTAAATTCAGACTGGTTCCAAATGTACTGCCAGATAGTAGCATTTCTCTAGTGTTTGTTTTCATCCTGGCTTGTAAGAATGCCCTGCCACTTCTGCCCTGCAATATCCCTTGCTATTAGGATTTTGGCATCACCTTGGGTCCTTAATGCCAGAAATGGGAATTGCTTCATACTGTGGAAAAATACCCATTAAAATATTAAGACCAGTAAAACCTCGTTTCTGCTTGGGCTATTTGTGGATTTCAGACATCCTGAGAAGTTTACCACCCCTGTAATTAATTGTCATTGTCATCACTTCATAATAAAAATAATTGCATGGCCGGGCATGGTGGCTCAAGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGTCAGATCACCTAAGGTCAGGAGATCAAGACCAGCCTGACCAACATGAAGAAACCCCATCTTTACTAAAAATACACAATTAGCCGGGCGTGGTGGCGCATGCCTATAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCGGAGGTTGCGGTGAGCCGAGATTGCACCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTCTCAATAATAAGAAGAAGAATTGCGTGAATATTTCTTTAAAACTATGATGAGATAACATACCAGATTATCAAATGGATTCAGTAGTGGGTGTGCCATTTATTGCACACTGAGAGATGACCAAGTCATTCTGAAATATCTTTATTAATATATCCTTCCTAGGATTTTTCATCCTAACTTCTCCATAGGTAGTTACTTAGCATAACATCTCTGTGGCCAGATGTATCCCACTACTAAAAGGGCAAAGTAAGCTGTGGCTGCCCTGGTAGATACAATGAGTAAGTGCACAGTGATGGCTATAAATGTTTTCATCTCATAATCCCATGTCCAGACCAGCAATTTGCTCTGAAAGCTCTTACCTGTGTCTGTTTCAATGGCTCTTGATCACTTGCCTGCACGTCCAGAATTCCTTATTTATTCATTGAAAATTAGCGTTCTTTATCCCTTTGTTTTGCAAGTTCAGCTTTTTAGAGATGGCTAAAATGGTCTAATCTTTCTTGGCAAAGGCAATTCTGAGCTGCAGATTAGACTACAAGTGGCTTGGGTACATGTTGTCTTTAAACAAGCGAAGAGGAAAACTTTGAGCTCTATTCAGACTTGGTGAAGTGTGGTAAATTTATGATGAAAGCTACTGACTGTATTACACATGATTAATTCTGAAGCCCATATTAAGATGATCTTTTCAGCAGTTCAGCATTGCTCTTCTAACTGAACAGTTTCAAGGCTGGGATTTCAGCAATTAATCAGTTCAGAATTGCTAATGATCCTGGCGGAGGGTGGTAGCAAAAGGGGGAGGATGTCATTAGCTTCTCTAGCCTGCCTTTTTTCAGTGCCCTGTGGCAGTATGGAGTGAGGCAACATGAAAGAAAGATGGCCTGACCTTCATGGCAGTATTGTGCAACACGTAAATACTGGTGTGAGTGGCTGTGGCTATGGCTAGTAAATGATGGCCCTTGGTAAACAAAGTTATTTATCAGACAATACCTACCAGCTAGGTCAACTGTGCCCATAATTGATCTGGTTAATTTCTTTTGCTGCCTATTGATTTTTATTTGGTTGATAGATAATAGCTAGAGGACTCTAAATTTCTTTGGGGAAGAACATGAACCCCTTCTAAGCCTTCTTACGAGAGAATTGATCGCTTTTGCACTGACCTTTAGTAACATCCTGATTTCAGTGTTTTGTAACTATCAGAGGGTTGAGTCTTGGTTTTAAGCCATGTATATCTGTAGCATAACTTTCTGTGTAGGCTAGTTACCTCTCAGCTTATAAAGTGTAGGCTGATAAATTTATAGTACAGTAGAGTGTCACTATGCAAAGAAACGATCTTAGGGAATCGAATGATATCTGCTATTAAAGCAAAATTAATATATATTTTTTCTTTTTACTTTTTTTTTTTTTTAAAGACATGAAATCTCACTGTATTGCCCAGGCTGGTCTTGGTCTCAGACTCTTGAGCTCAAGCAGTCCTCCCACCTCAGCTTCCCAAAGTGCTGGGATTATAGGCATGAGCTGCCGTGTCTGGCCCAGTATATATTTTTTAAGTTTTAAGTTTTGTGGTACGTAGTAGGTTTATAATATTATTTTGAATCCTTAGTTGTAATTTTATGTCTGCTGATGTGTACATAATTTTTATTAAACTATTTATTTGAGACTTCAGGTATCTTTTTTTTTTTTTTGAGACGGAGTCTCGCACTCTCGCCCAGGCTAGAGTGCAGTGGCGCCATCTCGGCTTACTGCAAGCTCTGCTTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGAGACTACAGGTGCCCGCCACCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTTGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGAGATTACAGGCGTGAGCCACCGCGCCCAGCCGAGACTTCAGGTGTCTTAGAATTTTTTAAATGTACCCTTTCTGAGAAAAACAGAGACTTAAAGCTAGGATAACTGGTATTCTATTTTTTTTTTTTTTTTTTTTTTACCTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTAAAAAAAAAAAAAAAAAAATTCACTTTAAATAGTTCCAGGACACGTGTAGAACGTGCAGGATTGCTACATAGGTAAACATATGCCATGGTGGAATAACTAGTATTCTGAGCTGTGTGCTAGAGGTAACTCATGATAATGGAATATTTGATTTAATTTCAGATGCTCGTGTACAAGTTTGCCAGAAAACACCACATCACTTTAACTAATCTAATTACTGAAGAGACTACTCATGTTGTTATGAAAACAGGTATACCAAGAACCTTTACAGAATACCTTGCATCTGCTGCATAAAACCACATGAGGCGAGGCACGGTGGCGCATGCCTGTAATCGCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACGAGATTAGGAGATCGAGACCATCCTGGCCAGCATGGTGAAACCCCGTCTCTACTAAAAAATAAAAAAATTAGCTGGGTGTGGTCGCGTGCGCCTGTAGTCCCAGCTACTCGTGAGGCTGAGGCAGGAGAATCACTTGAACCGGGGAGATGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCATTCCAGCCTGGCGACAGAGCAAGGCTCCGTCTCAAAAAAAAAAAAAAAAAACGTGAAAAAATAAGAATATTTGTTGAGCATAGCATGGATGATAGTCTTCTAATAGTCAATCAATTACTTTATGAAAGACAAATAATAGTTTTGCTGCTTCCTTACCTCCTTTTGTTTTGGGTTAAGATTTGGAGTGTGGGCCAGGCACGGTGGCTCACACCTGTAATCTCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACGTGTTGAAACCCCGTCTCTACTAAAAATATAAAAATTAGGTGGGCGTGGTGGCAGGCACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGCAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCAGTGACCCAAGATCGCACCATTGCACTCCAGCCTGGGGACAAGAGCGAGATTCTTGTCTCAAAAAAAAAAAAAAAAAAAAAAGGTTTGGAGGGTGGTGAGCTGAGATAGTCAACTATTAACTCCTATCTACCTGCTGGGACTACACTGGTGAGGTGGAGCCTAAGTCCTAAAACAACAAGTGAGGCAGCTGGACGCGGTGGCTCGCATCAGTAATCCCAGCACTTTGGGAGCCTGAGGCGGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGGCCAATATGGTAAAACCCAGTCTCTACTAAAAATACATAAATTGGCTGGGCGTGGTGGTGTGCACCTGTAATCCCAGCTACTTGGGAGGCTGACACAGAAGAATTGCTTGAACTCTGGAGGCTGAGGTTGCAGTCAGCTGAGATCCTGCCACTGCACTCCAGCCTGGCGACAGAGTGAGACTCTGTCTCAACAACAACAAAAGAAAGAACAAGTGAGGCAAAACCTGGAGACCCCAGCTTCATGTAACACCTAGTTTGAGTATTGTTGAGAGTTTTTCAGGAAAAAAGTCTGATAACAGCTCCGAGATAGTCTTAACATATGAAAAAGCAAAAAAGGGAGGAGACAGATCATTTGTCCTATACCTTTCTCTTTTAAGGTTTTAATTATAACTTGTGTAATACAGGAGACCTCTGGGTGTTTTTAGTTGACTATAAACTAAATCTGAGTACACATTTCAGGGCTGCTAAAAATGCTTATTTGAAACTGGGCCGTATTAACACAAGCAGAGGCTCTGGAGCAAGTGAAGTACAGATCCAGAGCCCCACTGTATTCTCCAATGGAGTGATTGCCTGAAAGATGATGTCAGTTTTAAGCACCGTGCTTGGTTTTTAACATGGTCACTGACAAATTGGAGAGTGTTTATCCAGAGGTAGATGGTAAAGATACATAAAAGTAACTTGAAATACTGTCTTTTGAAGAAGAAATGAGAAGATTTAAGGAAATAAGACACTGTCTTCAAGTATCTGAAGAACCGTTACCCGGAAGAGAACTGTTATCTGGAACAGGATTAAGACTCACTCATGGGGCTCCAGAAAGCAGACGAGTGCATGGAGGACGCAGAAGATGCAGATTGTGTGGCTCAACTCTAAAATCTTTCTAACAAAATTAGTTCTCTGGATGTGTTCCAGTTCACTTGATGATGATTCTTTTGTTTTTGTTTTTGTTTTTGAGGTGTAGTTTTTCACTCTTGTTGCCCAGGCTGCTGGAGTGCAATGGCACGATCTTGGCTTGCTGCAACCTCCCCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGAATGCACCACCATACCTAATTTTGTATTTTTAGTAGAGACAGGGTTTTTCCATGTCAGTCAGGCTGGTCTTGGACTCCCGACCTCAGGTGATCCACCTACCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCATCGCGCCTAGCCTATGATGATTCTTTTCACAGAGATACAGGCACTTAAGGAGAGGATCTAAACCCCTTGGACACATTGCCGTTGAACTTCTAAGATCTTAGGTTTCCACTTACTCATGAAAATTATACCACAGGGTCAGAGGGTAGTGTTCATTGGAGCCAGGTGCCAGAACAAGTTATTACAAACTACTATTTTAGAGAAAAATGTCATTAAAGTTTAAGATACCTTAAGCTATAGGTTTGCATCAAAGTTAATGAAAGGTAAAAAGATGCCAAGCGTGGTGGCTCAGGCCTGTAATCCCAGCGCTTTGGGGGGCCAAGGCGGGCAGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCATCTCTAGTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCATCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGCAGAGCTTGCCGTGAGCTGAGATCCAGCCACTGCACTCCAGCCTGGCTGACAGAGCAAGACTGCATCTCAAAAAAAAAAAAAAAAAAAAATGCAAATCAAATCTAAAGTAGTTCAGTCTTTAAACTCAAAGCCAATACATTTGCTTTGAACTACAAATGAACTGAAGTTTTTAAGTGTAATAAATGTTACTAAATCGGCTTTTGTAGCAGTTAAACAAAAAACTTCAAAAATTGTAAGGATTCTGTGAGGGAGCATGGCTGCTGCTGCTGCTGCTGCTTGCAGATAGCCTGCTGTGTTTAGGATTTAGTTAAATACATTTCTCCTGTTTAAAACTAAATGGTCTTTCCTTAGTTTGCTTAGTTCTTCAGAAGGGCCTTTGAAACACTGGGAAATAAACAAGTGATTCTTTAGCTACTGCTTTCTGAAATACTTATATAAAAGCTCTGCACTGTATTCTCCCATCCCTCTCAGGGGAATATTAGAGGGTTAGGACTCCCCAGGTAGACATTCTAGGGGTGAAAATTTGTCATTACATTGACATTTCAGATTTAGGTTTTCAACAATACTGTTTTCTTCTTTCACATATTGCCATCTAGTAATATAGATGTTCTCCGTCCACATTAATCAAAACTATTGACATGGATAATTCCTAATTCCTTGAACACTATAATGGAGATCTATAGCTAGCCTTGGCGTCTAGAAGATGGGTGTTGAGAAGAGGGAGTGGACAGATATTTCCTCTGGTCTTAACTTCATATCAGCCTCCCCTAGACTTCCAAATATCCATACCTGCTGGTTATAATTAGTGGTGTTTTCAGCCTCTGATTCTGTCACCAGGGGTTTTAGAATCATAAATCCAGATTGATCTTGGGAGTGTAAAAAACTGAGGCTCTTTAGCTTCTTAGGACAGCACTTCCTGATTTTGTTTTCAACTTCTAATCCTTTGAGTGTTTTTCATTCTGCAGATGCTGAGTTTGTGTGTGAACGGACACTGAAATATTTTCTAGGAATTGCGGGAGGAAAATGGGTAGTTAGCTATTTCTGTAAGTATAATACTATTTCTCCCCTCCTCCCTTTAACACCTCAGAATTGCATTTTTACACCTAACGTTTAACACCTAAGGTTTTTGCTGATGCTGAGTCTGAGTTACCAAAAGGTCTTTAATTGTAATACTAAACTACTTTTATCTTTAATATCACTTTGTTCAGATAAGCTGGTGATGCTGGGAAAATGGGTCTCTTTTATAACTAATAGGACCTAATCTGCTCCTAGCAATGTTAGCATATGAGCTAGGGATTTATTTAATAGTCGGCAGGAATCCATGTGCAGCAGGCAAACTTATAATGTTTAAATTAAACATCAACTCTGTCTCCAGAAGGAAACTGCTGCTACAAGCCTTATTAAAGGGCTGTGGCTTTAGAGGGAAGGACCTCTCCTCTGTCATTCTTCCTGTGCTCTTTTGTGAATCGCTGACCTCTCTATCTCCGTGAAAAGAGCACGTTCTTCTGCTGTATGTAACCTGTCTTTTCTATGATCTCTTTAGGGGTGACCCAGTCTATTAAAGAAAGAAAAATGCTGAATGAGGTAAGTACTTGATGTTACAAACTAACCAGAGATATTCATTCAGTCATATAGTTAAAAATGTATTTGCTTCCTTCCATCAATGCACCACTTTCCTTAACAATGCACAAATTTTCCATGATAATGAGGATCATCAAGAATTATGCAGGCCTGCACTGTGGCTCATACCTATAATCCCAGCGCTTTGGGAGGCTGAGGCGCTTGGATCACCTGATGTCGGGAGTTCAAGACCAGCCTGACCAACATGGAGAAACCCCGTTTCTACTAAAAATACAAAATTAGCCGGGCTTGGTGGCACTTGCCTGTAATTCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGGGGTTGCAGTGAGCTGAGATCGCATCATTGCACTCTAACCTGGGCAACAAGAGCAAAACTCCATCAAAAGAAAAAAAAAATCGGGTGCAGTGGCTCATGCCTGTAATCCTAACACTGTGGGAGGCCAAGACAGGCAGATTGCCTGAGCTCAGGAGTTCGAGATCAGCCTGGGCAACATGGTGAAACCCTGTCTCTACTAAAATACAAAAAATTACTCAGCGTGGTGGCATGCGCCTTTAGTTCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCTCTTGAACCCGGGAGGTGGAGGTTGCAATGAGCCAAGATCGTGCCACTGCACTCCAACCTGGCAACAGAGCGAGACTCCGTCTTAAAAAAAAAAAAAATTTTGCAGCGCAAACCAGGATATCCTCTGTTCTCATTTGTTCTAGATTTCAAAAGAAACAGTCCTTTCTTTGGGGAAAAGAGAAAGGAAAAGGAGTTTTATAAAAGGAAAGAAAAGATTCATAAGAACAAGAAGTGGGCCCACTTGCATATACCTTTGTAGAAAACTGTTCACTGTTGTTGAAGAAAAGCTCTTCATATTAATATGCAGTCCAGATGCAGTGGCTCACACTTATAATCTCAGCCCTTTGGGAGGCTGAGACAGGAAGATTACTTGAGGCCAGGAGTTTGAAACCAGCCTGGGCAACATAGTGAGACTCTGTCTCCACAAAATTTTTTTTTAATTAGCCGGGCATGGCAGTGTGCTTCTGTAGTCTTAGCTACTGAGGAAGCTAAGCCAGAAGAATCACTTGAGCCCAGGAGTTCAAGGCTGCAGTGAGCTATGATCATACCATTGCACTCTTGCACTTGCACAGAGCAAGACCCTGTCTCTTAAAAAAAAAAAAGTGTGTGTGTGCATATGCATATATACATATATATACATGCAAATGTATCTGTTTATAATTCAGATTGCTTCAAAAAGATGTTGCACTTTATGATACTGAGAACAGTGAGAAGTAAATAAGATAGAGTGTAGGAGGAGGAATAATTTCAGAACAGCCATCTGAGAACTTCTGTGACAACAGATCAGGCAAAATGAAATGTGAAAGTAATTTTATAGGCCAGGCGTGGTGGCTCATGCCTATAATCCCAGCACTTTGAGTGGCCAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGTCAACATGGTGAAACCTTGTCTCTACTAAAAACACAAAAAAATTAGTCGAGCGTGGTGGCATGTGCCTGTAATCCTAGCTGCTGGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCTAGATTGCACCACTGCACTCCAGCCTGTGAGACAGAATGAGACCCTGTCTTAAAAAAAAAAAAAAAGTAATTTTATAAACTATTGTGCACAATTCGATGTATTCATAATTAATTAAATGATTATTTTTGTTGGTTTTAACTTTTATTCAGTGGCTATTTATTGGGAGCCTACTGTGTTCTGGGCACTAGGAATGCAACAGTAAATAAGACTAACTAAGTCCCTGGTAGGATTCAGGTTCTGTCGAGGGGAGATACACAATAAAGATGAATTTAAGATAACAATAAATGCTATGGAGAAATATACAGAACAGTGGAATAGTATTAGCTGTCAAAGGTTGTTGATTACTTTCGTTTAAGGAGGCCAGGGAAAGCCTTTCTGAAAAAATTGAGCTGAGACCTAAATAACAAGAAATAATTGTCCTTGAAAAATGAAGGGAATGCATCTTATAGGCAGAGGAATAGCAAACATAAAGGTCTTGAGGTAATAATGAGTGTGGTTTTTTGATTTCTGTATTTTGGTTTTTTTGAGATGGTGTCTCCCTCTATCCCCCAGGCTGGAGTGCAGTGGCACAATCTTGGCTCACTGCAAACTCTGTCTCCTGGGTTCAAGCAATTCTCCTGCCTTGGCCTCCTGAGTAGCTGGTATTACAGGCACGCGTGCTACCACACCCGACTAGTTTTTATTTTTAGTAGAGATGGGGTTTTACCACGTTGGTCAGGCTGGTCTCAAACTCCTGAACTCAAGTGATCCAACCACCTCAACCTCCCAAAGTGCTGGGATCACAGGTGTGAGCCACTGTGCCCGGCCAGAGCTTGGTTTATTTTTTAAAAGATAGGCCAATGTTGGTCGTGTGTGGTGGCTCGTGCCTATAATCCCAGCACTTTGGGAAGCCAAGGCAGGCAAATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAACTAGCATGGTGTGGTGGTGTGTGCCTGTAATCCCAGTGCCTGTAATCCCAGCTACTCCAGAGGCTGAGGCAGGAGAATCACTTGAACCGAAAGGTAGGAGTTACAGTGAGCCAAGATCGCATCACTGCACTCCAGCCTGAACGACAGAGCAAGACTCCTGTCTCAAGAAATAATAATGATAAAAGGTTCGGGCACAGTGGCTCACACCTGTAATTCCAGCACTCTAGGAGGCCGAGGCAGGCAGATCCCCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGCAAAACCCCATCTCTACTAAAAAATGCAAAAATTAGCTGGGCACGGCTGGGTGTGGTGGCTCATTCCTGTAATCCCAGCACTTTGGGAGGTCAAGGCGGACAGATCACTGAGGTAGAAACCCTGTCTCTACTAAAAATACAAAAATTTGCCCAGCGTGGTGGCGCGTGCCTCTAATCCCAGCTACACGGGAGGCTGAGACAAGAGAATCACTTCATCAACCCGGGAGGTGGAGGTTGTGGTGAGCTGAGATCGCACCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAAAAACAAAAAAAAATTAGCTGGGAATGGTGGCATGTGCCTGTAATCACAGCTACTTGGGAGGCTGGGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGATTGCAGTGAGCTGAGATTGCGCCACTGCACTCCAGGCTGGGCGAAAGAGCAAGACTCCGTCTCAAAAATAATAATAATAATAATAATAGGCCAGTGTAGCTGGAGTAATTTGCAAATTATGTGTGGAGGCAGAGATTACACAAGGAATGGGAGAAGGTCATAGATGAGGGCCAGATCACATAGTATTTGGTGGTAAGGAATTCAGATTTTATCCTTGTGGTAATTGGTGGTGTGGAGATGGTTAAAAACAAGGTTGGTTTGGGATGGGTTTGAAGAGAGGACTTGCTAATGGATTAAATTTGGAGGATAAGGTAAAGAGAAATTGAAGGAGTGACACTTGGGTTTTGGCTTGAACAATAGATCTTGTTAGTAATATTAAATTAGATGAAGAAGGCATGGTAGGGAATATGGGGGAGTGGGAAAGGCAGGAAGCAGGAATGGAACCAGGAACTCTGTTTTAGATGTGAGAATTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTGACAGCATCTCGTTCTGTTGCCCAGGCTAGAGTGCATGGAGTGCGGTAGCACGATCTCAGCTCACTCCAACCTCCGCCTCCCGGTTCAAGTGATTTTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCTGCCACAATGCCTGGCTAATACTTGTATTTTTAGTAGAGATGGGGTTTTACCATGTTGGCCAGGCTGGTCTTAAACTCCTGACCTCAGGTAATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTGCAGGTGTGAGCCACTGTGCCCGGCCAGATGCATGAATTTTGAGATGTATACTAGACTTCTGGATAGAGAAGTTAAGTAGGCAGTTGGACACATTGTATGAAGCTCAGGGGTACAAGGAGGACTATGAACATGGGAGTCTTCTGACAAATTTATCACTAGACTCCTCATTCAAGTAACTAGGAAATGTCAGATATTCTTCCCCTAGTAATAGCCAGTGGTTATACTCTTGCCTTTAGTTTTCTTCACAATACTCTTGGCAACACATAAGGCCTTCCCTACAATCTGAGTTTCAGTCAGAATTGTTTCTGAGCGTTCTTCCTCAAATTTCTCCCCAGTCTCATTATTCTTTATTCTCATGTCCATGACCAGTCATAATAGTAATTATGAAAAACCTCTAACTTTCTTTAGTGCATTGAATGTATATTTTATCATTTTGGTTGTGTTAACTGTAAATCTCTCAGTGGAAATCTGAAAAGCCTTTATTTCCTTAGATGATAATATACAATTGATTTAGGAGATAGGGAATTTTTCAGTTACCTTTATAACAGCACAGTATTAGCAGTCTAATCTAAATGCTAAGTGAATGTTTTGAGAGGAGATAGATGTTGAAAATTAAAATACATTAAGTCCCAGTGAGGTGAAAAGCCGATTGTTAAGTTCTGCACACAAAAGATTTGCTTCAGTGAATTGATTTCAACAGCTGAGATCCTAGTCATTTCACCTGGTCTACCAAAAAGAATGATTTTACTTGCTTTTGGTCAAATCTCTGCCCAGCAATTCTTTTTCTTTCTTTCTTTTTTTTGTTTTATGTGTGTGTGTGTGTGTGTTTTTTTTTAGCAGAGTCTCACTTTGTCACCCAGGCGGGAGTGTGGTGGTATGATCACAGTTCACTGCAGCCTCCAACTCCTGGGCTCAAGTGATCCTCCAGCTTCAGCTTTTCAAGAAATTGGGACTGCAGGCACATGCAACTATGCCTGGCTGAGGTTTTATGTATCTTTTTTCTAGAGAAGGGGTCTCACTGTGTTGCCCAGCTGGGTCTCCAGCTCCTGGTCTCAAGCTGTCCTCCTGCCTCAGCCTCCCAAAGTGCCAAAGTGCTAGGGTTATAGGTGTGAGCCATTGGTGCCCAGCTACTGCCTGCCTGGCAATTCTGAATGCCTTAAATTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTTTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCATGATCGTGGCTCACAGCAACCTCTGCCTCCTGGATTCCAGCAATTCTCATGCCTCAGCTTCCCGAGTAGCTGGGACTACAGGTGCATGCCACCACGCCCAGCTAATTTTTGGTTTTTTTGTTTGTTTGTTTGTTTGTTTTGAGACGGAGTCTCGCTCAGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCCGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCTGCCACTACACCCGGCTAATTTTTTTGTATTTTAAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCTGTCTCGGCCTCCCAAAGTCCTGGGATTACAGGCGTGAGCCACCACACCCGGCCTAATTTTTTTTTTTTTAATTTTATTTTTAATTTTTTGAGATGCGAGATGGAGTCTCGCTCTGTTACCCAGGCTGGAGTGCAGTGGCACCATCTCAGCTCACTGCAACCTCCACCTCCTGCATTCAAAAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCCTGCCACCACGCCCAACTAATTTTTTGTATTTTTAGTAGAGATGAGGTTTCACCATGTTGGTCAGACTGGTGTCGAACTCCTGACCTCAAGTGATCTGCCTGCCTCAGTCTCCCAAAGTGCTAGGATTACAGGGGTGAGCCACTGCGCCTGGCCTGAATGCCTTAAATATGACGTGTCTGCTCCACTTCCATTGAAGGAAGCTTCTCTTTCTCTTATCCTGATGGGTTGTGTTTGGTTTCTTTCAGCATGATTTTGAAGTCAGAGGAGATGTGGTCAATGGAAGAAACCACCAAGGTCCAAAGCGAGCAAGAGAATCCCAGGACAGAAAGGTAAAGCTCCCTCCCTCAAGTTGACAAAAATCTCACCCCACCACTCTGTATTCCACTCCCCTTTGCAGAGATGGGCCGCTTCATTTTGTAAGACTTATTACATACATACACAGTGCTAGATACTTTCACACAGGTTCTTTTTTCACTCTTCCATCCCAACCACATAAATAAGTATTGTCTCTACTTTATGAATGATAAAACTAAGAGATTTAGAGAGGCTGTGTAATTTGGATTCCCGTCTCGGGTTCAGATCTTAGCTGATAAGTGGAAGAGCTGGGACTTTAAGCAGATGAGAATCTAAAGACTTTGCTCTTTTCACTTCACTGGGGTGTCTTTCTCTCTCTCTCTCTTGCTCTCTCTCTCTCTTTTTTTTTTTCCCAAGACGGAGTCTCACTCCATTGCCCAGGCCAGAGTGCAGTGGTGCGATCTCAGCTCACTGAAAACTCATCTTGCCCAGGCTGGTCTTGAACCCCTGACCTTGTGATCCTCCCGCCTTGGCCTCCCCAAGTGCTGGGATAGGCGTGAGCCACCGTGCCCAGCCAATAATAGCTAAAATTTATATAATGTTCACTGGGCCAGGCACAGCGGCTCGTTCCTGTTATCCCAGCACTTTGGGAAGCTGAGGCAGGCAGATCGCTTGAGCCAAGGAGTTCGATACCAGCCTGGGCAACATGGCAAAACCCCATCTCTACCAAAAAAAATATACAAAAATTAGCCAGGCGTGGTGGCATGTACTTGTAGTTCCAGCTACTCGGAAGGCTGAGTTGAGAGTATCTCTTGAGCCCAAGAAGAGGGGACTACAGTGAACGGAGATTGCGCCACTGCACTCCAGCCTAGACGACAGACAGAAGATCTCAAAAGAAAAAAAAAAAAAAAAGATCACTTTATGCTGGGACTGCTCTAAAGGCCCAACCATGTTTTAACTAATTAACAATTTTATGACAACTCTATGAGCTATGTACTGTAATTATGCCTATATTACAGATGTGAAAATTGAGGCTCAGAGAGGTTGAATAAGTTGCTCAAAGTCACACAGGTAATAAGTGATGGAACTAGAAGTTGAACTCAGGAAGTCTAGCTCCAAGTCTAAATTCTTTGTTAATTTATTTTTCGGGCCAGAGTCTTACTCTGTCACCCAGGCTGGAGTGCAGTGCCACTATCTCTGCTCACTGCAACCTTCACCTCCCAAGTTCAAACCTTGTTCAATTCTTGTGCCTTGGCCTCCCAAGTGGCTAGGATTACAGGCATGTGCCACAACAACTAGCTAATTTTTTGTCTGATTCTGTTGGCCAGTCTGGAGTGCAGTGGCGCAATCTCAGCTCACTGCAGTCTCCAGCTCCCAGGTTCAAGTGATTCTCGTGCCTTAGCCTCCCAAATAGCTGGGATTACAGGCACGTGCCACCACACCGAGATAGTTTTTTGTATTTTTAATAGAAACAAGGTTTCAACATGTTGGCCAGGCTGGTCTCAAATTCCAGACCTCAGATCATCTGCCCGCCTCAGGCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACCCGGCCTTAATTTTTATATTTTTATTAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGCCTTGATCTCCTGGCCTCCAGTGATCCACCCGCCTTGGCTTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTGCACCCGGCCTCCAATTCTAAACTCTTAACAACAATACTATAGTTTCTTGAAAAGTTGTTGAAGGCTTCACGGAGGGAAAAAAAATGGAGCATTCTAACAACTTTGCAGATGAGACCCAAGAAGACTCAATGACTTTCTCCTGATCATATTGTAGCAGATGACTTAGCCAGAACTCTGACTTCCTCACAGGGAGAAAGTCTGCAAGATTTCACACTTACCTGTCAGGCCTGAGCTGGCTGCTTTCTCAGCTCCCTAAGTGCTATGTTCCCAGTCTGCTTTTCTTCCTTTTTCAAGTGTGCACTACCAGGCATTTCAGAACATCCCAGGCTGGTCGCGGTGGCTCACACCTGTGATCCCAGCACTTTGGGAGCCCAAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAGTTAACTGGGCGTGGTGGTAGGCACCTGTAATCCTAGCTCAGGATTACTCGGGAGGCTGAGGCTAGAGAATCGGTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATTGCGCCACTGCACTCTAGCCTGGGGACAAGAGGGAGACTTCATCTCAAAAAAAAAAAAAAAATCCCAGCTGGGCACAGCGGCTCACTTCTGTAATCCCAGCACTTTAGGAGGCCAAGGCAGGAGGATCACTTGAGCCCAGGAGTTCAAGACTAGCCTGGGCAACATAGTAAGACCCTGTCTCTACAAAAAAATTTAAAAATTAATTGGGTGTCGTAGCACACTCTTGTATTCCCAGCTACTCAGGAGGCTGAGGTGAGAAGAATGCTTGAGTCTGGGAGGTCGAGGCTGCAGTGAGCCATGATGGTGCTACTGCACTCCAGCCTGGCCAACATTGTGAGACCTTGTCTCAAAACAAAACAAAACATCCTTCTACTGAGCACTTTCTGTCCCTTTATAGAAACTTAAGAGGGAACCAGTAGAGGTAATTTCCTAAGGAAAACTGCTTTGGGACATGATCACAAATGAAGCCTGGAGTTTTGAACTGCTGAGGTCAGCCTGTTTTTACCTTCTGAGCCTATCAAGTAATTGTTCCAGATGCCAAGAAAAGCTGCTGGCCTTATTTCTGCTTCTGCCTTTACCACAGGGGAGCGCCATGTGAGCCAGTCCTCTGTTTTTCCTCCACTGTATGCTAGGCAGTATTAGCACCAGATTCTTCCCCTCTTTAAAAAGAAATTCTAGTGCTTTGGATTTTTTCCTCCATGCAGAATAGCAATGATGGAAAGTATGTGGTCAAAGTAATGACATTCTGAAAATACTAAATGTCACCATAGTATTTTTCTCTGGAAGAGAAATGTATATGTAGAGGTGAAACTTCAAATTTCTTTTTTTTTTTTTTTAAGACGAAGCTTTGCTCTTCTTGCCCAGGCTGAAGTACAATGGCGTGATCTTGGCTCACCGCAATCTCTGCCTCCAGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTAAGTAGCTAGGATTACAGGCATGTGCCACCACGCCCAGCTGATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCACGCTGGTCTTGAACTCCCGACCCCAAGTGATCCACCCACCTCGGCCTCCCAAAGTGCTAGGATTACAGGCCACCGCGCCCGGCCTGAAACTTCAAATTTCTTTTTTTTTTTGAGACAGAGTCTCGCTATGTCACCCAGGCTGGAGTGCAGTGGCGCCGTCTCGGCTCACTACCAGCTCCACTCCACCTCCTGGGTTCACACCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGCCCGCCACCATGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACGGGTTTTCACTGTGTTAGACGGGATGGTCTCCATCTCTTGACCTCGTGATCCGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTACGCCAAGCCCGAAACTTCAAATTTCTTATCTCATAACTAGGCATCCTCATCACTGAGTGTTAGCCTGGATATAAACATTCCTAATCTTTTGTACTTTTCATGTCAGCATTTGGCTCCACTTGGCTGCCTGGGGAGAACTTCTAGCATTATGAGCATGCAGGTCCTATCAACAGGTTGGGGGTGCGGTTTATTCATACAGGTAGTGAGAGTGGCACAGATGGATGCTGTCCCTTAAAACAAACAGACTTGTCTTTGGGAGCCTGAGGCGGGTGGATCATGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATAGTGAAACCCCGTTTCTACTAAAAATACAAAAAATTAGCCGGGTGTGGTGGTGTGCACCTGTAATCCCAGCTACTAGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCGAGATGGCACCATTGCACTCCAGCCCAGGCGACAGTGCAAGACTGCGTCTCAAAAAAAAAAAAAAAACACACAGACTTGTCCTACTGCCATTTCTTTTCACTCTGGCGGTAAAGTAAGAGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTCTGTCCGTCTGTCTGTCAAGGGGGAGGGTGACCACTTTCTAAAAGGCCATCCGTGTATTTTTAGCTTCCTGATTTTTTTCTCTATCGCAGTCTCTTTGAAGCCAGGTGAATTTTAGGCCTTGGCAATTTTCTTTTTATTGCAATGGGAAGGTCAAGACACTGAGAGTCACCCAAAACATATCCATCCAAAATGATACAATTTTAGGGTTTATTTTTAAGTGATACCCAAGTTATTTGCTAAGAACCTATGCCAGTGTGTTTATGAGAATTTGCACTGTCCCACACTGTTGCCACCAGCCACATGGGACTGTTTAAATTTAAATTTTACAAATTAGCCAGTCATGGTGGTGTGCACTTGTAGTCCCAGCTACTTAGGAGGCTGAGGCAAGAGGATTGCTTGAGCCCAGAAGTTCAATACTGCAGCAAGCTATGATCGTGCCACTGTACTCCAGCCTGAGTGACAGAATGAGACCTCATCTCTTCAAAAAAAAAGAAAAAAATTAAAATATGAAGTTTAGTTCTTCATTCACCCTAACCACATCTCCAGTGCTCAATAACTATATGTGACTCATGGCTACCTTATTAGCATAGATATAGAACATTGTGACTATCACAGAAAGTTGTTTTGAACAGTGTTGCCAAGCCCTGTAAGTGGAAGAGGCAGTGCAGTGTGATCTGTGTCTTCAGGAAACCAGGTAGTCAGACTAGTTCAATGAGGAGAGGCAGAACCTGGCTTCACTTCTAGATTAAAAACTGCTTAGGTGGCCTAAAGATACAATGGCCATTCTCAGAGTAGTGAGAAGGAAGGAACAGATGTTTAGGGGGCTAGAAGAAAGTCAGAGAGGGCCGGGCGCAGTGGCTTATGCCTGTAATCCCAGCACTTTGGAAGGCCAAGACAGGCAGATCACGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGTGCGCGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTGAACCCTGGAGGCAGAGGTTGCAGTGAGCCCAGATCGCACCACTACGCTCCAGCCTAGGTGACAGAGAGAGACTCCGTCTCAAAAAAAAAAAAAAAAGTCAGAGGAGACAAGGAGCATGTACACCTAAAATCAACATAGACCCCTCTGTTGATGGGGTCATAGTGAGTACTTGAGGTACCAAGTCTGGATAAACATCAAACTTCAGCCAATAACTTTGAGTTTCTAGCCATCCAAGCCTCTTATTAAACATACAGAAGGACCTTTTTTCCCTTGCATCTAACAAGTTAAAGCACCTGCAGAGATCATTAGGGAGGAGCCTTGGCCTGATTGGTGACAAAAGTGAGATGCTCAGTCCTTGAATGACAAAGAATGCCTGTAGAGTGCAGGTCAACTACATATGCACTTCAAGAAGATCTTCTGAAATCCAGTAGTGTTCTGGACATTGGACTGCTTGTCCCTGGGAAGTAGCAGCAGAAATCATCAGGTGGTGAACAGAAGAAAAAGAAAAGCTCTTCCTTTTTGAAAGTCTGTTTTTTGAATAAAAGCCAATATTCTTTTATAACTAGATTTTCCTTCTCTCCATTCCCCTGTCCCTCTCTCTTCCTCTCTTCTTCCAGATCTTCAGGGGGCTAGAAATCTGTTGCTATGGGCCCTTCACCAACATGCCCACAGGTAAGAGCCTGGGAGAACCCCAGAGTTCCAGCACCAGCCTTTGTCTTACATAGTGGAGTATTATAAGCAAGATCCCACGATGGGGGTTCCTCAGATTGCTGAAATGTTCTAGAGGCTATTCTATTTCTCTACCACTCTCCAAACAAAACAGCACCTAAATGTTATCCTATGGCAAAAAAAAACTATACCTTGTCCCCCTTCTCAAGAGCATGAAGGTGGTTAATAGTTAGGATTCAGTATGTTATGTGTTCAGATGGCGTTGAGCTGCTGTTAGTGCCAACATGTTAGTGAGAAAATATCTTTGGATAGGTAAAAATCAAGGAGGAGTTCTCCTCTTCCTAAACCATCTTAATTTACTTACATAGAAGAAAGCACAGCAGCTGGCCCACCACGGACGGGCCCAGAGCAGGGGAAGATTCTCGGTGAACATTTCTTTTTTTTTTTCTTTTTTTTTGAGGTCGAGTCTCTGTTGCCCAGGCCAGAGTGCAATGGCGCGATCTCGGCTCACTGCAACCTCCACCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAATAGCTGAGACTACAGGCGTGTGCCACCACGCCCGACTAATTTTTTGTATTTTTTTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAATATGGTCCCGATCTCCTGACCTCGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACTGTGCCCAGCCCTCTCCATGAACATTTTCTAATTAAACTTGACACTTAATACAATGTTATGCTTAGGACTGCTATAAAGCTTACCTCTGGAGTTGCGCAGCACAAAGGCCTTGGTGTGTGTATAAATTTGGTTTGTTCTTTTCACAGCAAAAGCTACCCACCTTTGCCTCCTGTGCCTGCTTCTGCCCAGGGACTTAGGTCCTCTTACACCTTAGAGAAAGGCCTTAGCATCTGGTCACAGGCAGATGAGTGACAGCAAGAAAACCTGGCTGCAATGTAATTTTGTTTCCATCCTCTTTATTAGTTATCAATTGGATTTTTATGAAATTTCCAAGTTCCACTCAAGGATTTCTCAGTGTTTTTTTACTTTGGTATAGTGGAAACCAGGGTTGCCAGAAAGTATTATTTTGGGGGTGAGTTAGTCAACCTTCGTTCAGTCAGACAGACAGGAGCACCTCAGCAATTCCCAGAAACGGGCTGATGGGAAAGAGCAACATACATGAATGTCTTGAAGAACACAGCCAACAGAGCCCATTGGGCAGTTCTGATTTTCCAGGTACACAGCATCTCCACAGTCTCTTCTGATTTTTATTCCCCTGAGTATATGGATTCCAGCTCAGCATGTAGCCTTTCCCTGCTGAGTCTCTAACCAGGATAACATGTATTTTTTTGACTGGATGAATTATCTTCCCATCTCTTGACATTTACAGTAATTACCACCAAGTATGGTATTTTCAGTGGCCGTGATTATCAGTTACCAACACAGAATTAGGATGAAGGGAGGAAGGGAGGGAAGGAAGGTGGGTGTTTTTTCACACAGTGTCTTAGCCAGCAATTTAGCAAATTAATGGAAATTAGATCTTTGATTTTTTTTTCTTTCAAGCATTTTATTTGAGAGACTATCAAACCTTATACCAAGTGGCCTTATGGAGACTGATAACCAGAGTACATGGCATATCAGTGGCAAATTGACTTAAAATCCATACCCCTACTATTTTAAGACCATTGTCCTTTGGAGCAGAGAGACAGACTCTCCCATTGAGAGGTCTTGCTATAAGCCTTCATCCGGAGAGTGTAGGGTAGAGGGCCTGGGTTAAGTATGCAGATTACTGCAGTGATTTTACATCTAAATGTCCATTTTAGATCAACTGGAATGGATGGTACAGCTGTGTGGTGCTTCTGTGGTGAAGGAGCTTTCATCATTCACCCTTGGCACAGTAAGTATTGGGTGCCCTGTCAGAGAGGGAGGACACAATATTCTCTCCTGTGAGCAAGACTGGCACCTGTCAGTCCCTATGGATGCCCCTACTGTAGCCTCAGAAGTCTTCTCTGCCCACATACCTGTGCCAAAAGACTCCATCTGTAAGGGATGGGTAAGGATTTGAGAACTGCACATATTAAATATACTGAGGGAAGACTTTTTCCCTCTAACTCTTTTTCCCATATGTCCCTCCCCCTCCTCTCTGTGACTGCCCCAGCATACTGTGTTTCAACAAATCATCAAGAAATGATGGGCTGGAGGCTGGGCATGGTGGCTCATGTCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACTTGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTGTACTAAAAAAAAAAAAACAAAAAGTAGCCAGGCCTGGTGGAGCATGCCTGTAATGCCAGCTATTTGGGAAGTTGAGGTGTGAGCATCGCTTGAACGTGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGCACCACTGCACTCCAGACTGGGTGACAGAGTGAGACTTTGTCTAAAAAAAAAAAAAAAGAGAGAGAGAGAAAAGCTAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACGAGGTCAAGAGATCGAGACCATCCTGGCCAACCAACATGGCGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTAGGGGCGCACGCCTGTAGTCCCAGCTACTTGAGGGGCTGGGGCAGGAGAATCGCTTGAACCCCGGAGGCGGAGGTTGCAGTGAGCCAAGATCGCGCCACTGCACTCCAGCCCGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAGAGAGAGAGAGAAATGATGGGCTGGGCCAGTGCCCCACCCCTGTAATCACAACACTGGGAGGCCAAGGTGGGAGAATCGCTTGAGCCTGGGAGCTGAAGACCAGCCTGGGCAATACAGTAGGACCTCATGTCTACAAAAAAATTATTAAAAATTAGCCAAGGCTGGGTGCGGTGGCTCATGCCTATAATCCCGGGGGTGAAGTTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACATGGCAAAACCCTGTCTCTACCAAAAATACAAAAAAATTAGCCAGGGGTGGTGGTACGTGTCTGTAGTTCCAGCTACTTAGGAGGCTGAGATGGAAGGATTGCTTGAGCCCAGGAGGCAGAGGTGGCAGTGAGCTGAGATCACACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCTGTCTCAAAAACAAACAAAAAAAATGATGAAGTGACAGTTCCAGTAGTCCTACTTTGACACTTTGAATGCTCTTTCCTTCCTGGGGATCCAGGGTGTCCACCCAATTGTGGTTGTGCAGCCAGATGCCTGGACAGAGGACAATGGCTTCCATGGTAAGGTGCCTGCATGTACCTGTGCTATATGGGGTCCTTTTGCATGGGTTTGGTTTATCACTCATTACCTGGTGCTTGAGTAGCACAGTTCTTGGCACATTTTAAATATTTGTTGAATGAATGGCTAAAATGTCTTTTTGATGTTTTTATTGTTATTTGTTTTATATTGTAAAAGTAATACATGAACTGTTTCCATGGGGTGGGAGTAAGATATGAATGTTCATCACAAAAACATAAATCAAGGCCGGGCATGGTGGCTCATGCCTATAATTCCAGCACTTTGGGAGGTCAAGATGGAGGTCAAGGTGGGAGCCTAGAAGTTCGAGACCAGCCTGGGCAACATAAGGAGACTTCATCTGTACAACAAATTTAAAAAGTAGCTGGGTGTGGTGGCAGATGCCTGTAGTCGCAGCTACTTGGGAAGCTGAGGTGGGAGGATCACTTGAGCTCAGGAGGTTGATGCTTCAGTGAGCCACGATCACACCACTGTACTCCAGCCTGGGCGACAGAGCGAGACCGTGTCTCAAAAAGAAAAAAGAAAGTATAAATTTACACAAAAACAATAAAATAATCCCAGTAATTCCACCACTTGGAGATGATCACCATAAAACTCCACCAGGCATATGTGCGTATATATACACGTGTATTTTATAAAATGTGATCATAATTACACTGTTTTGCTTTTTTCCTTAAGATATTACATACATTTTTCCACATCGTTAAATTACAGTGCTGTTTTCCTGGTGGCTTTCCTTTAACAGATTGAAGTTCATGTTAATACAGTTGCCAGAGGCTGTGGGCTTTCACTGTCACCAGGAGTCACTCCTAGGGCCTCTTCAGAGCAAGGCCTTATGTCCTGAAGCATTGCCTTTTTTTTTTTTTTTTGAGGTGGAGTCTCACTCTGTCACTTAGCAGGCTGGAGTGCAGTGGCCCAGTCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTTAAATGATTCTCCTGCCTCAGCCTCAGGGCGGATCACCTGACATCAGGAGTTTGAGACCAGCCTGGCCAATATGGCGAAACCCCATCTCTACTAAAAATACTAAAAAAAATTAGCCAGGCATGGTGGCACGCACTTGTAGTCCCAGCTACTTGGGAGACTGAGGCAGGAGAATCGCTTGAACCCAGGATGTTGAGGTTGCAGTGAGCTGAGATCACACCATCACAATCCAGCCTGAGTGACAGAGTGAGACTCCATCTGAAAAAAAAGAAAAAACAATTAGCCTGGCATGGTGGCAGGCACCTGTAATCCCTGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCGTGCCATTGCATTCCAGGCTGAGCAACAAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAGGCCAGGTGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGATCACCTGAGGTCAGGAGTTCCAGAGCAGCCTGGCCAACATTGTGAAACCCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGATGGCATGTGCCTGTAATTCCAGCTACTCAGGAGGCAGAGACAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGAATGAGCCGAGATTGCGCCATCACACTCTAGCCTCGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAATTAGCTTCTACCTCATTAATCCTAAGAACTCATACAACCAGGACCCTGGAGTCGATTGATTAGAGCCTAGTCCAGGAGAATGAATTGACACTAATCTCTGCTTGTGTTCTCTGTCTCCAGCAATTGGGCAGATGTGTGAGGCACCTGTGGTGACCCGAGAGTGGGTGTTGGACAGTGTAGCACTCTACCAGTGCCAGGAGCTGGACACCTACCTGATA,dna,BRCA1 Locus,GCF_000001405.13,,Protein coding +47,urn:mavedb:00000097-h-1,TTAATTTCAGGAGCCTACAAGAAAGTACGAGATTTAGTCAACTTGTTGAAGAGCTATTGAAAATCATTTGTGCTTTTCAGCTTGACACAGGTTTGGAGTGTAAGTGTTG,dna,BRCA1 Exon 5,GCF_000001405.13,,Protein coding +48,urn:mavedb:00000061-h-1,TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAAGAACAGTGGTCAATGTGCGAAATGGAATGAGCTTGCATGACTGCCTTATGAAAGCACTCAAGGTGAGGGGC,dna,RAF,GCF_000001405.26,P04049,Protein coding +49,urn:mavedb:00000066-a-1,ATGGACGAGGAATACGATGTGATCGTGCTGGGGACCGGTCTCACCGAATGCATCCTGTCGGGCATCATGTCTGTGAACGGGAAGAAGGTGCTGCACATGGACCGGAACCCCTACTACGGGGGCGAGAGCTCCTCCATCACACCCCTGGAGGAGCTGTATAAGCGTTTTCAGTTGCTGGAGGGGCCCCCTGAGTCGATGGGCCGAGGCCGAGACTGGAATGTTGACCTGATTCCCAAATTCCTCATGGCTAACGGGCAGCTGGTAAAGATGCTACTGTATACAGAGGTGACTCGCTACCTGGACTTCAAGGTGGTGGAGGGCAGCTTTGTCTACAAGGGGGGCAAGATCTACAAAGTGCCGTCCACTGAGACTGAGGCCTTGGCTTCCAATCTGATGGGCATGTTTGAGAAACGGCGCTTCCGCAAGTTCCTGGTGTTTGTGGCAAACTTCGATGAGAATGACCCCAAGACCTTTGAGGGCGTTGACCCCCAGACTACCAGCATGCGTGACGTCTACCGGAAGTTTGATCTGGGCCAGGATGTCATCGATTTCACTGGCCATGCCCTGGCGCTCTACCGCACTGATGACTACCTGGACCAGCCCTGCCTTGAGACCGTCAACCGCATCAAGTTGTACAGTGAGTCCCTGGCCCGGTATGGCAAGAGCCCATATTTATACCCGCTCTACGGCTTGGGCGAGCTGCCCCAGGGTTTTGCAAGATTGAGTGCCATCTATGGGGGGACATATATGCTGAACAAACCTGTGGATGACATCATCATGGAGAACGGCAAGGTGGTGGGCGTGAAGTCTGAGGGAGAGGTGGCCCGCTGCAAGCAGCTGATCTGTGACCCCAGCTACATCCCGGACCGTGTGCGGAAGGCTGGCCAGGTTATCCGCATCATCTGTATCCTTAGCCACCCCATCAAGAACACCAACGACGCCAACTCCTGCCAAATAATCATCCCCCAGAACCAGGTCAACAGGAAGTCAGACATCTACGTGTGCATGATCTCCTATGCACACAACGTGGCGGCCCAGGGCAAGTACATAGCTATTGCCAGCACTACTGTGGAGACCACGGACCCTGAAAAGGAGGTGGAGCCGGCTCTGGAGCTGTTGGAGCCCATTGACCAGAAGTTTGTGGCTATCAGTGACTTGTATGAGCCCATTGATGATGGTTGTGAGAGCCAGGTGTTCTGTTCCTGCTCCTACGATGCCACCACACACTTTGAGACAACCTGCAACGACATCAAAGACATCTACAAACGCATGGCTGGCACGGCCTTTGACTTTGAGAACATGAAGCGCAAACAGAACGACGTCTTTGGAGAAGCTGAGCAGTGA,dna,GDI1,GCF_000001405.26,P31150,Protein coding +50,urn:mavedb:00000021-a-1,GGCGTGTCCGCCTGTTGGAATATGCTTCTCAGGTCTTCTGGGAAACAGATGTTTTGTGGAAGTGGAAGATTTTGGAAGTAGTGCCTTATCATGTGAAACCACAGGGCAGCTGATCTCTTCAGGCTTTCTTGATGTGAATGACAGCTTTGTTTCATCCACTTTGGTGGGTAAAAGAAGGCAAATTCCCCTGTGGTACTTTTGGTGCCAGGTTTAGCCATATGACGAAGCTTTACATAAAACAGTACAAGTATCTCCATTGTCCTTTATGATCCTCCATGAGTGTTTTCACTTAGTCTGATGAAGGGTTCACTCCAGTCTTTTCGGATGATAAAATGCTTCGGCTGTCAGTCTAATAAGGGATTCCCTGAGGAGTTTGGAGGCTGTAAGAGCACCCCCCGTCTCAATGCCAGTGCTTCTTATCTCAGCCTCTCCTGCACTCCTTTACCCCCGT,dna,IRF4 enhancer,GCF_000001405.26,,Regulatory +51,urn:mavedb:00000108-a-3,ATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGCATGAAGATGGCCCTGAGGATGACCCACAGTTGGTAGGCATCACTGCTCGTAACATTCCACGAGGGCCCCAGTTGGCTGCCCAGAACTTGGGCATCAGCCTGGCCAACTTGTTGCTGAGCAAAGGAGCCAAAAACATCCTGGATGTTGCACGGCAGCTTAACGATGCCCATTAA,dna,HMBS,GCF_000001405.26,P08397,Protein coding +52,urn:mavedb:00000094-a-15,MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS,protein,KCNQ1,GCF_000001405.26,,Protein coding +53,urn:mavedb:00000031-a-1,TCGCGGGGGTGGCCGGGGCCAGGGCTTCCCACGTGCGCAGCAGGACGCAGCGCTGCCTGAAACTCGCGCCGCGAGGAGAGGGCGGGGCCGCGGAAAGGAAGGGGAGGGGCTGGGAGGGCCCGGAGGGGGCTGGGCCGGGGACCCGGGAGGGGTCGGGACGGGGCGGGGTCCGCGCGGAGGAGGCGGAGCTGGAAGGTGAAGGGGCAGGACGGGTGCCCGGGTCCCCAGTCCCTCCGCCACGTGGGAAGCGCGGTCCTGG,dna,TERT promoter,GCF_000001405.26,,Regulatory +54,urn:mavedb:00000094-a-2,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +55,urn:mavedb:00000094-a-4,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +56,urn:mavedb:00000059-a-1,ACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAGTCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACACCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAGCGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAACACTTTTCGGCATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGTTCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGTGGTAATCTACTGGGACGGAACAGCTTTGAGGTGCGTGTTTGTGCCTGTCCTGGGAGAGACCGGCGCACAGAGGAAGAGAATCTCCGCAAGAAA,dna,p53,GCF_000001405.26,P04637,Protein coding +57,urn:mavedb:00000094-a-1,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +58,urn:mavedb:00000083-i-1,AGTTACCACCGGGAGCTCCAGCACAGTGAAATGGACAGAAGGGCAGAGCAA,dna,Minigene exon - AC-rich enhancer,GCF_000001405.13,,Other noncoding +59,urn:mavedb:00000045-g-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +60,urn:mavedb:00000097-i-1,AGTGTGAGCAGGGAGAAGCCAGAATTGACAGCTTCAACAGAAAGGGTCAACAAAAGAATGTCCATGGTGGTGTCTGGCCTGACCCCAGAAGAATTTGTGAGTGTAT,dna,BRCA1 Exon 15,GCF_000001405.13,,Protein coding +61,urn:mavedb:00000097-w-1,TCCTGGGGATCCAGGGTGTCCACCCAATTGTGGTTGTGCAGCCAGATGCCTGGACAGAGGACAATGGCTTCCATGGTAAGGTGCCTGCATGTACCTGTGC,dna,BRCA1 Exon 22,GCF_000001405.13,,Protein coding +62,urn:mavedb:00000045-j-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +63,urn:mavedb:00000103-b-1,MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS,protein,MAPK1,GCF_000001405.26,,Protein coding +64,urn:mavedb:00000097-g-1,TTAATTTCAGGAGCCTACAAGAAAGTACGAGATTTAGTCAACTTGTTGAAGAGCTATTGAAAATCATTTGTGCTTTTCAGCTTGACACAGGTTTGGAGTGTAAGTGTTG,dna,BRCA1 Exon 5,GCF_000001405.13,,Protein coding +65,urn:mavedb:00000026-a-1,GGTAAGTCAACATGAAATTATAAACCATGTTTAACTAACCCACAAGAAAAACAGAAAAAGAAAACAGATACATGAAAATCTGAGAGGAAAAAAAAAAAACAGAGAACACAATGGGAAGCTTCATTCAATGTAAGGGTACTAGAAGTTCTAGCCAGTGCAATTAAGAGGAAAAAAATAAATAAAAAGGCATATGTGTTGAAAGGAAGAAATTAAACTGTCTTTATTTGCAAATGACATGATTATCAGCACAGATAATCAAGATAAATATATAAAAAGATTTCTGAAACTAATAAGTTAGTTCAGTAAGGTCGTAAGCTATAAGACAAACAAAGGAAAATCAATTGTATTTGAATGTATCGACAGTAAACATATGGACATTAAAATTAACAATACAATATAATTTATATTTATTAAAAATATAAAATGCTTAGGCATAAATCTAACAAAACCCCCACAGTACTTG,dna,MYC enhancer (rs11986220),GCF_000001405.26,,Regulatory +66,urn:mavedb:00000083-j-1,AGTTTCTTTTGGGAGCTCCAGCACAGTGAAATGGACAGAAGGGCAGAGCAA,dna,Minigene exon - pyrimidine sequence,GCF_000001405.13,,Other noncoding +67,urn:mavedb:00000049-a-4,ATGGTGAACGAAGCCAGAGGAAACAGCAGCCTCAACCCCTGCTTGGAGGGCAGTGCCAGCAGTGGCAGTGAGAGCTCCAAAGATAGTTCGAGATGTTCCACCCCGGGCCTGGACCCCGAGCGGCATGAGAGACTCCGGGAGAAGATGAGGCGGCGATTGGAATCTGGTGACAAGTGGTTCTCCCTGGAATTCTTCCCTCCTCGAACTGCTGAGGGAGCTGTCAATCTCATCTCAAGGTTTGACCGGATGGCAGCAGGTGGCCCCCTCTACATAGACGTGACCTGGCACCCAGCAGGTGACCCTGGCTCAGACAAGGAGACCTCCTCCATGATGATCGCCAGCACCGCCGTGAACTACTGTGGCCTGGAGACCATCCTGCACATGACCTGCTGCCGTCAGCGCCTGGAGGAGATCACGGGCCATCTGCACAAAGCTAAGCAGCTGGGCCTGAAGAACATCATGGCGCTGCGGGGAGACCCAATAGGTGACCAGTGGGAAGAGGAGGAGGGAGGCTTCAACTACGCAGTGGACCTGGTGAAGCACATCCGAAGTGAGTTTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCGAAGCAGGGAGCTTTGAGGCTGACCTGAAGCACTTGAAGGAGAAGGTGTCTGCGGGAGCCGATTTCATCATCACGCAGCTTTTCTTTGAGGCTGACACATTCTTCCGCTTTGTGAAGGCATGCACCGACATGGGCATCACTTGCCCCATCGTCCCCGGGATCTTTCCCATCCAGGGCTACCACTCCCTTCGGCAGCTTGTGAAGCTGTCCAAGCTGGAGGTGCCACAGGAGATCAAGGACGTGATTGAGCCAATCAAAGACAACGATGCTGCCATCCGCAACTATGGCATCGAGCTGGCCGTGAGCCTGTGCCAGGAGCTTCTGGCCAGTGGCTTGGTGCCAGGCCTCCACTTCTACACCCTCAACCGCGAGATGGCTACCACAGAGGTGCTGAAGCGCCTGGGGATGTGGACTGAGGACCCCAGGCGTCCCCTACCCTGGGCTCTCAGCGCCCACCCCAAGCGCCGAGAGGAAGATGTACGTCCCATCTTCTGGGCCTCCAGACCAAAGAGTTACATCTACCGTACCCAGGAGTGGGACGAGTTCCCTAACGGCCGCTGGGGCAATTCCTCTTCCCCTGCCTTTGGGGAGCTGAAGGACTACTACCTCTTCTACCTGAAGAGCAAGTCCCCCAAGGAGGAGCTGCTGAAGATGTGGGGGGAGGAGCTGACCAGTGAAGAAAGTGTCTTTGAAGTCTTCGTTCTTTACCTCTCGGGAGAACCAAACCGGAATGGTCACAAAGTGACTTGCCTGCCCTGGAACGATGAGCCCCTGGCGGCTGAGACCAGCCTGCTGAAGGAGGAGCTGCTGCGGGTGAACCGCCAGGGCATCCTCACCATCAACTCACAGCCCAACATCAACGGGAAGCCGTCCTCCGACCCCATCGTGGGCTGGGGCCCCAGCGGGGGCTATGTCTTCCAGAAGGCCTACTTAGAGTTTTTCACTTCCCGCGAGACAGCGGAAGCACTTCTGCAAGTGCTGAAGAAGTACGAGCTCCGGGTTAATTACCACCTTGTCAATGTGAAGGGTGAAAACATCACCAATGCCCCTGAACTGCAGCCGAATGCTGTCACTTGGGGCATCTTCCCTGGGCGAGAGATCATCCAGCCCACCGTAGTGGATCCCGTCAGCTTCATGTTCTGGAAGGACGAGGCCTTTGCCCTGTGGATTGAGCGGTGGGGAAAGCTGTATGAGGAGGAGTCCCCGTCCCGCACCATCATCCAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAATGACTTCCCACTGGACAACTGCCTCTGGCAGGTGGTGGAAGACACATTGGAGCTTCTCAACAGGCCCACCCAGAATGCGAGAGAAACGGAGGCTCCATGA,dna,MTHFR,GCF_000001405.26,P42898,Protein coding +68,urn:mavedb:00000083-e-1,AGTTATATATGGGAGCTCCAGCACAGTGAAATGGACAGAAGGGCAGAGCAA,dna,Minigene exon - hnRNP D binding site,GCF_000001405.13,,Other noncoding +69,urn:mavedb:00000014-a-1,CCTAACACAGTAGCTGGTACCTGATAGGTGCCTATATGTGATGGATGGGTGGACAGCCCGACAGATGAAAAATGGACAATTATGAGGAGGGGAGAGTGCAGACAGGGGAAGCTTCACCTCCTTTACAATTTTGGGAGTCCACACGGCATGGCATACAAATTATTTCATTCCCATTGAGAAATAAAATCCAATTCTCCATCACCAAGAGAGCCTTCCGAAAGAGGCCCCCCTGGGCAAACGGCCACCGATGGAGAGGTCTGCCAGTCCTCTTCTACCCCACCCACGCCCCCACCCTAATCAGAGGCCAAACCCTTCCTGGAGCCTGTGATAAAAGCAACTGTTAGCTTGCACTAGACTAGCTTCAAAGTTGTATTGACCCTGGTGTGTTATGTCTAAGAGTAGATGCCATATCTCTTTTCTGGCCTATGTTATTACCTGTATGGACTTTGCACTGGAATCAGCTATCTGCTCTTACTTATGCACACCTGGGGCATAGAGCCAGCCCTGTATCGCTTTTCAGCCATCTCACTACAGATAACTCCCAAGTCCTGTCTAGCTGCCTTCCTTATCACAGGAATAGCACCCAAGGTCCATCAGTAC,dna,BCL11A enhancer,GCF_000001405.26,,Regulatory +70,urn:mavedb:00000097-b-1,AAGTTCATTGGAACAGAAAGAAATGGATTTATCTGCTCTTCGCGTTGAAGAAGTACAAAATGTCATTAATGCTATGCAGAAAATCTTAGAGTGTCCCATCTGGTAA,dna,BRCA1 Exon 2,GCF_000001405.13,,Protein coding +71,urn:mavedb:00000097-k-1,TTAATTTCAGATGCTCGTGTACAAGTTTGCCAGAAAACACCACATCACTTTAACTAATCTAATTACTGAAGAGACTACTCATGTTGTTATGAAAACAGGTATACCAAG,dna,BRCA1 Exon 16,GCF_000001405.13,,Protein coding +72,urn:mavedb:00000102-0-1,ATGACAGCCATCATCAAAGAGATCGTTAGCAGAAACAAAAGGAGATATCAAGAGGATGGATTCGACTTAGACTTGACCTATATTTATCCAAACATTATTGCTATGGGATTTCCTGCAGAAAGACTTGAAGGCGTATACAGGAACAATATTGATGATGTAGTAAGGTTTTTGGATTCAAAGCATAAAAACCATTACAAGATATACAATCTTTGTGCTGAAAGACATTATGACACCGCCAAATTTAATTGCAGAGTTGCACAATATCCTTTTGAAGACCATAACCCACCACAGCTAGAACTTATCAAACCCTTTTGTGAAGATCTTGACCAATGGCTAAGTGAAGATGACAATCATGTTGCAGCAATTCACTGTAAAGCTGGAAAGGGACGAACTGGTGTAATGATATGTGCATATTTATTACATCGGGGCAAATTTTTAAAGGCACAAGAGGCCCTAGATTTCTATGGGGAAGTAAGGACCAGAGACAAAAAGGGAGTAACTATTCCCAGTCAGAGGCGCTATGTGTATTATTATAGCTACCTGTTAAAGAATCATCTGGATTATAGACCAGTGGCACTGTTGTTTCACAAGATGATGTTTGAAACTATTCCAATGTTCAGTGGCGGAACTTGCAATCCTCAGTTTGTGGTCTGCCAGCTAAAGGTGAAGATATATTCCTCCAATTCAGGACCCACACGACGGGAAGACAAGTTCATGTACTTTGAGTTCCCTCAGCCGTTACCTGTGTGTGGTGATATCAAAGTAGAGTTCTTCCACAAACAGAACAAGATGCTAAAAAAGGACAAAATGTTTCACTTTTGGGTAAATACATTCTTCATACCAGGACCAGAGGAAACCTCAGAAAAAGTAGAAAATGGAAGTCTATGTGATCAAGAAATCGATAGCATTTGCAGTATAGAGCGTGCAGATAATGACAAGGAATATCTAGTACTTACTTTAACAAAAAATGATCTTGACAAAGCAAATAAAGACAAAGCCAACCGATACTTTTCTCCAAATTTTAAGGTGAAGCTGTACTTCACAAAAACAGTAGAGGAGCCGTCAAATCCAGAGGCTAGCAGTTCAACTTCTGTAACACCAGATGTTAGTGACAATGAACCTGATCATTATAGATATTCTGACACCACTGACTCTGATCCAGAGAATGAACCTTTTGATGAAGATCAGCATACACAAATTACAAAAGTCTGA,dna,PTEN,GCF_000001405.26,P60484,Protein coding +73,urn:mavedb:00000001-b-2,ATGTCTGACCAGGAGGCAAAACCTTCAACTGAGGACTTGGGGGATAAGAAGGAAGGTGAATATATTAAACTCAAAGTCATTGGACAGGATAGCAGTGAGATTCACTTCAAAGTGAAAATGACAACACATCTCAAGAAACTCAAAGAATCATACTGTCAAAGACAGGGTGTTCCAATGAATTCACTCAGGTTTCTCTTTGAGGGTCAGAGAATTGCTGATAATCATACTCCAAAAGAACTGGGAATGGAGGAAGAAGATGTGATTGAAGTTTATCAGGAACAAACGGGGGGTCATTCAACAGTTTAG,dna,SUMO1,GCF_000001405.26,P63165,Protein coding +74,urn:mavedb:00000094-a-3,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +75,urn:mavedb:00000061-g-1,TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAAGAACAGTGGTCAATGTGCGAAATGGAATGAGCTTGCATGACTGCCTTATGAAAGCACTCAAGGTGAGGGGC,dna,RAF,GCF_000001405.26,P04049,Protein coding +76,urn:mavedb:00000001-d-1,ATGGAGCATGCCTTTACCCCGTTGGAGCCCCTGCTTTCCACTGGGAATTTGAAGTACTGCCTTGTAATTCTTAATCAGCCTTTGGACAACTATTTTCGTCATCTTTGGAACAAAGCTCTTTTAAGAGCCTGTGCCGATGGAGGTGCCAACCGCTTATATGATATCACCGAAGGAGAGAGAGAAAGCTTTTTGCCTGAATTCATCAATGGAGACTTTGATTCTATTAGGCCTGAAGTCAGAGAATACTATGCTACTAAGGGATGTGAGCTCATTTCAACTCCTGATCAAGACCACACTGACTTTACTAAGTGCCTTAAAATGCTCCAAAAGAAGATAGAAGAAAAAGACTTAAAGGGAAAGCACAGGTTGCATGTAGACACTGGAATGGAGGGTGATTGGTGTGGCCTTATTCCTGTTGGACAGCCTTGTATGCAGGTTACAACCACAGGCCTCAAGTGGAACCTCACAAATGATGTGCTTGCTTTTGGAACATTGGTCAGTACTTCCAATACCTACGACGGGTCTGGTGTTGTGACTGTGGAAACTGACCACCCACTCCTCTGGACCATGGCCATCAAAAGCTAA,dna,TPK1,GCF_000001405.26,Q9H3S4,Protein coding +77,urn:mavedb:00000097-p-1,TGTAACCTGTCTTTTCTATGATCTCTTTAGGGGTGACCCAGTCTATTAAAGAAAGAAAAATGCTGAATGAGGTAAGTACTTGATGTTACAAACTAACCAGA,dna,BRCA1 Exon 18,GCF_000001405.13,,Protein coding +78,urn:mavedb:00000097-x-1,TCCTGGGGATCCAGGGTGTCCACCCAATTGTGGTTGTGCAGCCAGATGCCTGGACAGAGGACAATGGCTTCCATGGTAAGGTGCCTGCATGTACCTGTGC,dna,BRCA1 Exon 22,GCF_000001405.13,,Protein coding +79,urn:mavedb:00000055-a-1,ATGACGGCCAGCGCACAGCCGCGCGGGCGGCGGCCAGGAGTCGGAGTCGGAGTCGTGGTGACCAGCTGCAAGCATCCGCGTTGCGTCCTCCTGGGGAAGAGGAAAGGCTCGGTTGGAGCTGGCAGTTTCCAACTCCCTGGAGGTCATCTGGAGTTCGGTGAAACCTGGGAAGAATGTGCTCAAAGGGAAACCTGGGAAGAAGCAGCTCTTCACCTGAAAAATGTTCACTTTGCCTCAGTTGTGAATTCTTTCATTGAGAAGGAGAATTACCATTATGTTACTATATTAATGAAAGGAGAAGTGGATGTGACTCATGATTCAGAACCAAAGAATGTAGAGCCTGAAAAAAATGAAAGTTGGGAGTGGGTTCCTTGGGAAGAACTACCTCCCCTGGACCAGCTTTTCTGGGGACTGCGTTGTTTAAAAGAACAAGGCTATGATCCATTTAAAGAAGATCTGAACCATCTGGTGGGATACAAAGGAAATCATCTCTAG,dna,NUDT15,GCF_000001405.26,Q9NV35,Protein coding +80,urn:mavedb:00000094-a-10,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +81,urn:mavedb:00000045-i-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +82,urn:mavedb:00000032-a-1,ATACAGATAAATGCACACATGTATACGCGAAAGGTTAACTCGGCGGAGGACTCGCCCAAATAAGCACCGGGATTGCATTTAAAATAATAATAATAAATAAATAAATAAACTAGGAAGGAAAGCGGGGGGAGGGAAGCAGAAGTCGGGAAGAAAAGAGAAAAGCAGCAGGCTGATTACGAGGTGTCAAAACTGCCAGGAGCAAGAAGGTGATAGCAATCAGGGGTGAGAAGAGTGCGGCATTCGTGCGGGGCAACTAATTATCCGTCTCATTTGAGAAGAGCAGCATTTGAGGCAGCAGCGTTCGCCTGCTGAACGGTGACAGATTGGCGCGGAGGAGAGGGGAGGTGTTAAAACAATGGAGCCGGGCGCGCGAGCGCTGCTGCATGCTAATCAGCCCTCCCTCCGCCTGCCTGCCGCGCTCCCTCCTTCCTCCCGGCCTCCCTCCTCCGCGCTCCCTCCTCCCGCCTGCGGCGCTCCCTCCTTTCCAGCGGGCCCCGCGCCGCCGCCGCCACCCGCTTCCTGCTCCCTCGCTTTCCCGCGCGTCCTTCCCGCCGCTGGCGAGTGGAACCCAGCCACCGCCACCGAGTCCCA,dna,UC88 enhancer,GCF_000001405.26,,Regulatory +83,urn:mavedb:00000101-a-1,ATGACAGCCATCATCAAAGAGATCGTTAGCAGAAACAAAAGGAGATATCAAGAGGATGGATTCGACTTAGACTTGACCTATATTTATCCAAACATTATTGCTATGGGATTTCCTGCAGAAAGACTTGAAGGCGTATACAGGAACAATATTGATGATGTAGTAAGGTTTTTGGATTCAAAGCATAAAAACCATTACAAGATATACAATCTTTGTGCTGAAAGACATTATGACACCGCCAAATTTAATTGCAGAGTTGCACAATATCCTTTTGAAGACCATAACCCACCACAGCTAGAACTTATCAAACCCTTTTGTGAAGATCTTGACCAATGGCTAAGTGAAGATGACAATCATGTTGCAGCAATTCACTGTAAAGCTGGAAAGGGACGAACTGGTGTAATGATATGTGCATATTTATTACATCGGGGCAAATTTTTAAAGGCACAAGAGGCCCTAGATTTCTATGGGGAAGTAAGGACCAGAGACAAAAAGGGAGTAACTATTCCCAGTCAGAGGCGCTATGTGTATTATTATAGCTACCTGTTAAAGAATCATCTGGATTATAGACCAGTGGCACTGTTGTTTCACAAGATGATGTTTGAAACTATTCCAATGTTCAGTGGCGGAACTTGCAATCCTCAGTTTGTGGTCTGCCAGCTAAAGGTGAAGATATATTCCTCCAATTCAGGACCCACACGACGGGAAGACAAGTTCATGTACTTTGAGTTCCCTCAGCCGTTACCTGTGTGTGGTGATATCAAAGTAGAGTTCTTCCACAAACAGAACAAGATGCTAAAAAAGGACAAAATGTTTCACTTTTGGGTAAATACATTCTTCATACCAGGACCAGAGGAAACCTCAGAAAAAGTAGAAAATGGAAGTCTATGTGATCAAGAAATCGATAGCATTTGCAGTATAGAGCGTGCAGATAATGACAAGGAATATCTAGTACTTACTTTAACAAAAAATGATCTTGACAAAGCAAATAAAGACAAAGCCAACCGATACTTTTCTCCAAATTTTAAGGTGAAGCTGTACTTCACAAAAACAGTAGAGGAGCCGTCAAATCCAGAGGCTAGCAGTTCAACTTCTGTAACACCAGATGTTAGTGACAATGAACCTGATCATTATAGATATTCTGACACCACTGACTCTGATCCAGAGAATGAACCTTTTGATGAAGATCAGCATACACAAATTACAAAAGTCTGA,dna,PTEN,GCF_000001405.26,P60484,Protein coding +84,urn:mavedb:00000053-a-1,CCACGCCGCATCGTCATCCACCGTGGGTCAACGGGGTTAGGCTTCAATATCGTCGGTGGAGAGGATGGTGAGGGAATCTTCATCTCATTCATTCTGGCGGGAGGACCGGCCGATTTAAGCGGAGAACTTCGCAAAGGTGACCAGATCCTTTCGGTGAATGGCGTAGATTTGCGCAACGCATCACACGAACAGGCGGCCATCGCATTAAAGAACGCCGGCCAGACCGTTACGATTATCGCGCAGTATAAA,dna,PSD95 PDZ3,GCF_000001405.26,P78352,Protein coding +85,urn:mavedb:00000097-v-1,ATGTCCATTTTAGATCAACTGGAATGGATGGTACAGCTGTGTGGTGCTTCTGTGGTGAAGGAGCTTTCATCATTCACCCTTGGCACAGTAAGTATTGGGTGCCCT,dna,BRCA1 Exon 21,GCF_000001405.13,,Protein coding +86,urn:mavedb:00000091-a-1,HGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDF,protein,BRAF,GCF_000001405.13,P15056,Protein coding +87,urn:mavedb:00000048-c-1,GAGGGGATCAGTATATACACTTCAGATAACTACACCGAGGAAATGGGCTCAGGGGACTATGACTCCATGAAGGAACCCTGTTTCCGTGAAGAAAATGCTAATTTCAATAAAATCTTCCTGCCCACCATCTACTCCATCATCTTCTTAACTGGCATTGTGGGCAATGGATTGGTCATCCTGGTCATGGGTTACCAGAAGAAACTGAGAAGCATGACGGACAAGTACAGGCTGCACCTGTCAGTGGCCGACCTCCTCTTTGTCATCACGCTTCCCTTCTGGGCAGTTGATGCCGTGGCAAACTGGTACTTTGGGAACTTCCTATGCAAGGCAGTCCATGTCATCTACACAGTCAACCTCTACAGCAGTGTCCTCATCCTGGCCTTCATCAGTCTGGACCGCTACCTGGCCATCGTCCACGCCACCAACAGTCAGAGGCCAAGGAAGCTGTTGGCTGAAAAGGTGGTCTATGTTGGCGTCTGGATCCCTGCCCTCCTGCTGACTATTCCCGACTTCATCTTTGCCAACGTCAGTGAGGCAGATGACAGATATATCTGTGACCGCTTCTACCCCAATGACTTGTGGGTGGTTGTGTTCCAGTTTCAGCACATCATGGTTGGCCTTATCCTGCCTGGTATTGTCATCCTGTCCTGCTATTGCATTATCATCTCCAAGCTGTCACACTCCAAGGGCCACCAGAAGCGCAAGGCCCTCAAGACCACAGTCATCCTCATCCTGGCTTTCTTCGCCTGTTGGCTGCCTTACTACATTGGGATCAGCATCGACTCCTTCATCCTCCTGGAAATCATCAAGCAAGGGTGTGAGTTTGAGAACACTGTGCACAAGTGGATTTCCATCACCGAGGCCCTAGCTTTCTTCCACTGTTGTCTGAACCCCATCCTCTATGCTTTCCTTGGAGCCAAATTTAAAACCTCTGCCCAGCACGCACTCACCTCTGTGAGCAGAGGGTCCAGCCTCAAGATCCTCTCCAAAGGAAAGCGAGGTGGACATTCATCTGTTTCCACTGAGTCTGAGTCTTCAAGTTTTCACTCCAGC,dna,CXCR4,GCF_000001405.26,P61073,Protein coding +88,urn:mavedb:00000031-c-1,TCGCGGGGGTGGCCGGGGCCAGGGCTTCCCACGTGCGCAGCAGGACGCAGCGCTGCCTGAAACTCGCGCCGCGAGGAGAGGGCGGGGCCGCGGAAAGGAAGGGGAGGGGCTGGGAGGGCCCGGAGGGGGCTGGGCCGGGGACCCGGGAGGGGTCGGGACGGGGCGGGGTCCGCGCGGAGGAGGCGGAGCTGGAAGGTGAAGGGGCAGGACGGGTGCCCGGGTCCCCAGTCCCTCCGCCACGTGGGAAGCGCGGTCCTGG,dna,TERT promoter,GCF_000001405.26,,Regulatory +89,urn:mavedb:00000051-b-1,CTGACGTCTATCATCTCTGCGGTGGTTGGCATTCTGCTGGTCGTGGTCTTGGGCGTGGTCTTTGGCATCCTG,dna,ErbB2,GCF_000001405.26,P04626,Protein coding +90,urn:mavedb:00000097-m-1,CATTCTGCAGATGCTGAGTTTGTGTGTGAACGGACACTGAAATATTTTCTAGGAATTGCGGGAGGAAAATGGGTAGTTAGCTATTTCTGTAAGTATAA,dna,BRCA1 Exon 17,GCF_000001405.13,,Protein coding +91,urn:mavedb:00000001-b-1,ATGTCTGACCAGGAGGCAAAACCTTCAACTGAGGACTTGGGGGATAAGAAGGAAGGTGAATATATTAAACTCAAAGTCATTGGACAGGATAGCAGTGAGATTCACTTCAAAGTGAAAATGACAACACATCTCAAGAAACTCAAAGAATCATACTGTCAAAGACAGGGTGTTCCAATGAATTCACTCAGGTTTCTCTTTGAGGGTCAGAGAATTGCTGATAATCATACTCCAAAAGAACTGGGAATGGAGGAAGAAGATGTGATTGAAGTTTATCAGGAACAAACGGGGGGTCATTCAACAGTTTAG,dna,SUMO1,GCF_000001405.26,P63165,Protein coding +92,urn:mavedb:00000103-a-1,MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS,protein,MAPK1,GCF_000001405.26,,Protein coding +93,urn:mavedb:00000097-f-1,TATAATTTATAGATTTTGCATGCTGAAACTTCTCAACCAGAAGAAAGGGCCTTCACAGTGTCCTTTATGTAAGAATGATATAACCAAAAGGTATATAATT,dna,BRCA1 Exon 4,GCF_000001405.13,,Protein coding +94,urn:mavedb:00000057-b-1,ACGGAATATAAGCTGGTGGTGGTGGGCGCCGGCGGTGTGGGCAAGAGTGCGCTGACCATCCAGCTGATCCAGAACCATTTTGTGGACGAATACGACCCCACTATAGAGGATTCCTACCGGAAGCAGGTGGTCATTGATGGGGAGACGTGCCTGTTGGACATCCTGGATACCGCCGGCCAGGAGGAGTACAGCGCCATGCGGGACCAGTACATGCGCACCGGGGAGGGCTTCCTGTGTGTGTTTGCCATCAACAACACCAAGTCTTTTGAGGACATCCACCAGTACAGGGAGCAGATCAAACGGGTGAAGGACTCGGATGACGTGCCCATGGTGCTGGTGGGGAACAAGTGTGACCTGGCTGCACGCACTGTGGAATCTCGGCAGGCTCAGGACCTCGCCCGAAGCTACGGCATCCCCTACATCGAGACCTCGGCCAAGACCCGGCAGGGAGTGGAGGATGCCTTCTACACGTTGGTGCGTGAGATCCGGCAGCAC,dna,Ras,GCF_000001405.26,P01112,Protein coding +95,urn:mavedb:00000083-a-1,AGTTGCTGCTGGGAGCTCCAGCACAGTGAAATGGACAGAAGGGCAGAGCAA,dna,Minigene exon - Wilms’ tumor gene,GCF_000001405.13,,Other noncoding +96,urn:mavedb:00000097-s-1,CTCTCTTCCTCTCTTCTTCCAGATCTTCAGGGGGCTAGAAATCTGTTGCTATGGGCCCTTCACCAACATGCCCACAGGTAAGAGCCTGGGAGAACCCCAG,dna,BRCA1 Exon 20,GCF_000001405.13,,Protein coding +97,urn:mavedb:00000024-a-1,AAGCAGGACTCCTTATAGACAGGTACATCCAGGCAAAGCTGCATCAAACTTTTATACTGGAGAGGGCAACCACGCATTCGACATCATTGGGAATGATAACAAGGTGAGAACACATTGAGTGTTTACAGAGGGTTGACTATCAAAAGGAAAGTATGGTTTCAGATGATTTATGAGTTATTAATCAATCACATCTCCACCCAAGTTATGTGTTTACCTTGTCCCCACCCCGATCTGCATTTGCTGCTGACCTAAAAGAGCAGAGGAGGAGAGAACTTCTCTTTGCTGAGCCTTCGCCCTATGCTGGTGGATTGCTAGCACGTGATGTGTCCTTATTCGATTTTATACACAAAGAAACAGCCTCAGCGATGCCAGTCACAACAGCCAGGTGGTAAAGGTGGGTTTCCTGAAGGCATAAGAATAGCCCACAGGTCAGCCCACCAGGCCCACCGGGCCTGGGTCTGTGGCCCAGATGACCCTGCCCTTAGGGTCTGACATGAGAACAGAAATGGGTCAAGCCATCCTGCAGGGCACAGGAGAGCAAGAACTACATACAGCTCGGGGTTCCCTGACAAGCTGAATTGCTGGACCTTT,dna,MSMB promoter,GCF_000001405.26,,Regulatory +98,urn:mavedb:00000045-f-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +99,urn:mavedb:00000072-a-1,GQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG,protein,IGHG1,GCF_000001405.26,P01857,Protein coding +100,urn:mavedb:00000095-b-1,ATGGATTCTCTTGTGGTCCTTGTGCTCTGTCTCTCATGTTTGCTTCTCCTTTCACTCTGGAGACAGAGCTCTGGGAGAGGAAAACTCCCTCCTGGCCCCACTCCTCTCCCAGTGATTGGAAATATCCTACAGATAGGTATTAAGGACATCAGCAAATCCTTAACCAATCTCTCAAAGGTCTATGGCCCTGTGTTCACTCTGTATTTTGGCCTGAAACCCATAGTGGTGCTGCATGGATATGAAGCAGTGAAGGAAGCCCTGATTGATCTTGGAGAGGAGTTTTCTGGAAGAGGCATTTTCCCACTGGCTGAAAGAGCTAACAGAGGATTTGGAATTGTTTTCAGCAATGGAAAGAAATGGAAGGAGATCCGGCGTTTCTCCCTCATGACGCTGCGGAATTTTGGGATGGGGAAGAGGAGCATTGAGGACCGTGTTCAAGAGGAAGCCCGCTGCCTTGTGGAGGAGTTGAGAAAAACCAAGGCCTCACCCTGTGATCCCACTTTCATCCTGGGCTGTGCTCCCTGCAATGTGATCTGTAGTATCATATTTCACAAGCGGTTCGACTATAAGGACCAGCAATTCTTGAACCTTATGGAGAAACTGAATGAGAATATCAAAATTCTCTCAAGTCCGTGGATTCAGATTTGCAACAACTTTAGTCCCATTATTGATTATTTTCCGGGAACACACAACAAATTGCTGAAAAATGTAGCTTTTATGAAAAGTTACATTCTCGAGAAAGTCAAAGAGCATCAAGAGTCAATGGATATGAACAATCCTCAAGACTTCATTGATTGCTTCTTGATGAAAATGGAAAAGGAGAAACACAACCAACCATCTGAGTTCACAATCGAGTCACTGGAAAACACGGCCGTAGATCTCTTTGGTGCGGGGACGGAGACAACGAGTACGACTCTTAGATACGCGCTCCTTTTGTTGCTGAAGCACCCAGAAGTCACCGCGAAGGTGCAAGAAGAAATCGAGCGGGTAATCGGACGAAACAGATCCCCTTGTATGCAGGATAGAAGTCACATGCCCTACACAGATGCTGTGGTGCACGAGGTCCAGAGATACATTGACCTTCTCCCCACCAGCCTGCCCCATGCAGTGACCTGTGACATTAAATTCAGAAACTATCTCATTCCCAAGGGCACAACCATATTAATTTCCCTGACTTCTGTGCTACATGACAACAAAGAATTTCCCAACCCAGAGATGTTTGACCCTCATCACTTTCTGGATGAAGGTGGCAATTTCAAGAAGAGCAAGTATTTCATGCCTTTCTCAGCAGGAAAACGGATTTGTGTGGGAGAAGCCCTGGCCGGCATGGAGCTGTTTTTATTCCTGACCTCCATTTTACAGAACTTTAACCTGAAATCTCTGGTTGACCCAAAGAACCTTGACACCACTCCAGTTGTCAATGGATTTGCCTCTGTGCCGCCCTTCTACCAGCTGTGCTTCATTCCTGTC,dna,CYP2C9,GCF_000001405.26,P11712,Protein coding +101,urn:mavedb:00000001-a-1,ATGTCGGGGATCGCCCTCAGCAGACTCGCCCAGGAGAGGAAAGCATGGAGGAAAGACCACCCATTTGGTTTCGTGGCTGTCCCAACAAAAAATCCCGATGGCACGATGAACCTCATGAACTGGGAGTGCGCCATTCCAGGAAAGAAAGGGACTCCGTGGGAAGGAGGCTTGTTTAAACTACGGATGCTTTTCAAAGATGATTATCCATCTTCGCCACCAAAATGTAAATTCGAACCACCATTATTTCACCCGAATGTGTACCCTTCGGGGACAGTGTGCCTGTCCATCTTAGAGGAGGACAAGGACTGGAGGCCAGCCATCACAATCAAACAGATCCTATTAGGAATACAGGAACTTCTAAATGAACCAAATATCCAAGACCCAGCTCAAGCAGAGGCCTACACGATTTACTGCCAAAACAGAGTGGAGTACGAGAAAAGGGTCCGAGCACAAGCCAAGAAGTTTGCGCCCTCATAA,dna,UBE2I,GCF_000001405.26,P63279,Protein coding +102,urn:mavedb:00000023-a-1,AGCTCTTCACCGGAGACCCAAATACAACAAATCAAGTCGCCTGCCCTGGCGACACTTTCGAAGGACTGGAGTGGGAATCAGAGCTTCACGGGTTAAAAAGCCGATGTCACATCGGCCGTTCGAAACTCCTCCTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGACGTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGC,dna,LDLR promoter,GCF_000001405.26,,Regulatory +103,urn:mavedb:00000049-a-2,ATGGTGAACGAAGCCAGAGGAAACAGCAGCCTCAACCCCTGCTTGGAGGGCAGTGCCAGCAGTGGCAGTGAGAGCTCCAAAGATAGTTCGAGATGTTCCACCCCGGGCCTGGACCCCGAGCGGCATGAGAGACTCCGGGAGAAGATGAGGCGGCGATTGGAATCTGGTGACAAGTGGTTCTCCCTGGAATTCTTCCCTCCTCGAACTGCTGAGGGAGCTGTCAATCTCATCTCAAGGTTTGACCGGATGGCAGCAGGTGGCCCCCTCTACATAGACGTGACCTGGCACCCAGCAGGTGACCCTGGCTCAGACAAGGAGACCTCCTCCATGATGATCGCCAGCACCGCCGTGAACTACTGTGGCCTGGAGACCATCCTGCACATGACCTGCTGCCGTCAGCGCCTGGAGGAGATCACGGGCCATCTGCACAAAGCTAAGCAGCTGGGCCTGAAGAACATCATGGCGCTGCGGGGAGACCCAATAGGTGACCAGTGGGAAGAGGAGGAGGGAGGCTTCAACTACGCAGTGGACCTGGTGAAGCACATCCGAAGTGAGTTTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCGAAGCAGGGAGCTTTGAGGCTGACCTGAAGCACTTGAAGGAGAAGGTGTCTGCGGGAGCCGATTTCATCATCACGCAGCTTTTCTTTGAGGCTGACACATTCTTCCGCTTTGTGAAGGCATGCACCGACATGGGCATCACTTGCCCCATCGTCCCCGGGATCTTTCCCATCCAGGGCTACCACTCCCTTCGGCAGCTTGTGAAGCTGTCCAAGCTGGAGGTGCCACAGGAGATCAAGGACGTGATTGAGCCAATCAAAGACAACGATGCTGCCATCCGCAACTATGGCATCGAGCTGGCCGTGAGCCTGTGCCAGGAGCTTCTGGCCAGTGGCTTGGTGCCAGGCCTCCACTTCTACACCCTCAACCGCGAGATGGCTACCACAGAGGTGCTGAAGCGCCTGGGGATGTGGACTGAGGACCCCAGGCGTCCCCTACCCTGGGCTCTCAGCGCCCACCCCAAGCGCCGAGAGGAAGATGTACGTCCCATCTTCTGGGCCTCCAGACCAAAGAGTTACATCTACCGTACCCAGGAGTGGGACGAGTTCCCTAACGGCCGCTGGGGCAATTCCTCTTCCCCTGCCTTTGGGGAGCTGAAGGACTACTACCTCTTCTACCTGAAGAGCAAGTCCCCCAAGGAGGAGCTGCTGAAGATGTGGGGGGAGGAGCTGACCAGTGAAGAAAGTGTCTTTGAAGTCTTCGTTCTTTACCTCTCGGGAGAACCAAACCGGAATGGTCACAAAGTGACTTGCCTGCCCTGGAACGATGAGCCCCTGGCGGCTGAGACCAGCCTGCTGAAGGAGGAGCTGCTGCGGGTGAACCGCCAGGGCATCCTCACCATCAACTCACAGCCCAACATCAACGGGAAGCCGTCCTCCGACCCCATCGTGGGCTGGGGCCCCAGCGGGGGCTATGTCTTCCAGAAGGCCTACTTAGAGTTTTTCACTTCCCGCGAGACAGCGGAAGCACTTCTGCAAGTGCTGAAGAAGTACGAGCTCCGGGTTAATTACCACCTTGTCAATGTGAAGGGTGAAAACATCACCAATGCCCCTGAACTGCAGCCGAATGCTGTCACTTGGGGCATCTTCCCTGGGCGAGAGATCATCCAGCCCACCGTAGTGGATCCCGTCAGCTTCATGTTCTGGAAGGACGAGGCCTTTGCCCTGTGGATTGAGCGGTGGGGAAAGCTGTATGAGGAGGAGTCCCCGTCCCGCACCATCATCCAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAATGACTTCCCACTGGACAACTGCCTCTGGCAGGTGGTGGAAGACACATTGGAGCTTCTCAACAGGCCCACCCAGAATGCGAGAGAAACGGAGGCTCCATGA,dna,MTHFR,GCF_000001405.26,P42898,Protein coding +104,urn:mavedb:00000062-b-1,CTCTGTCTCTCATGTTTGCTTCTCCTTTCAATCTGGAGACAGAGCTCTGGGAGAGGAAAACTCCCTCCTGGCCCCACTCCTCTCCCAGTGATTGGAAATATCCTACAGATAGATATTAAGGATGTCAGCAAATCCTTAACCAATCTCTCAAAAATCTATGGCCCTGTGTTCACTCTGTATTTTGGCCTGGAACGCATGGTGGTGCTGCATGGATATGAAGTGGTGAAGGAAGCCCTGATTGATCTTGGAGAGGAGTTTTCTGGAAGAGGCCATTTCCCACTGGCTGAAAGAGCTAACAGAGGATTTGGAATCGTTTTCAGCAATGGAAAGAGATGGAAGGAGATCCGGCGTTTCTCCCTCATGACGCTGCGGAATTTTGGGATGGGGAAGAGGAGCATTGAGGACCGTGTTCAAGAGGAAGCCCGCTGCCTTGTGGAGGAGTTGAGAAAAACCAAGGCTTCACCCTGTGATCCCACTTTCATCCTGGGCTGTGCTCCCTGCAATGTGATCTGCTCCATTATTTTCCAGAAACGTTTCGATTATAAAGATCAGCAATTTCTTAACTTGATGGAAAAATTGAATGAAAACATCAGGATTGTAAGCACCCCCTGGATCCAGATATGCAATAATTTTCCCACTATCATTGATTATTTCCCGGGAACCCATAACAAATTACTTAAAAACCTTGCTTTTATGGAAAGTGATATTTTGGAGAAAGTAAAAGAACACCAAGAATCGATGGACATCAACAACCCTCGGGACTTTATTGATTGCTTCCTGATCAAAATGGAGAAGGAAAAGCAAAACCAACAGTCTGAATTCACTATTGAAAACTTGGTAATCACTGCAGCTGACTTACTTGGAGCTGGGACAGAGACAACAAGCACAACCCTGAGATATGCTCTCCTTCTCCTGCTGAAGCACCCAGAGGTCACAGCTAAAGTCCAGGAAGAGATTGAACGTGTCATTGGCAGAAACCGGAGCCCCTGCATGCAGGACAGGGGCCACATGCCCTACACAGATGCTGTGGTGCACGAGGTCCAGAGATACATCGACCTCATCCCCACCAGCCTGCCCCATGCAGTGACCTGTGACGTTAAATTCAGAAACTACCTCATTCCCAAGGGCACAACCATATTAACTTCCCTCACTTCTGTGCTACATGACAACAAAGAATTTCCCAACCCAGAGATGTTTGACCCTCGTCACTTTCTGGATGAAGGTGGAAATTTTAAGAAAAGTAACTACTTCATGCCTTTCTCAGCAGGAAAACGGATTTGTGTGGGAGAGGGCCTGGCCCGCATGGAGCTGTTTTTATTCCTGACCTTCATTTTACAGAACTTTAACCTGAAATCTCTGATTGACCCAAAGGACCTTGACACAACTCCTGTTGTCAATGGATTTGCTTCTGTCCCGCCCTTCTATCAGCTGTGCTTCATTCCT,dna,CYP2C19,GCF_000001405.26,P33261,Protein coding +105,urn:mavedb:00000094-a-12,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +106,urn:mavedb:00000057-c-1,ACGGAATATAAGCTGGTGGTGGTGGGCGCCGGCGGTGTGGGCAAGAGTGCGCTGACCATCCAGCTGATCCAGAACCATTTTGTGGACGAATACGACCCCACTATAGAGGATTCCTACCGGAAGCAGGTGGTCATTGATGGGGAGACGTGCCTGTTGGACATCCTGGATACCGCCGGCCAGGAGGAGTACAGCGCCATGCGGGACCAGTACATGCGCACCGGGGAGGGCTTCCTGTGTGTGTTTGCCATCAACAACACCAAGTCTTTTGAGGACATCCACCAGTACAGGGAGCAGATCAAACGGGTGAAGGACTCGGATGACGTGCCCATGGTGCTGGTGGGGAACAAGTGTGACCTGGCTGCACGCACTGTGGAATCTCGGCAGGCTCAGGACCTCGCCCGAAGCTACGGCATCCCCTACATCGAGACCTCGGCCAAGACCCGGCAGGGAGTGGAGGATGCCTTCTACACGTTGGTGCGTGAGATCCGGCAGCAC,dna,Ras,GCF_000001405.26,P01112,Protein coding +107,urn:mavedb:00000094-a-7,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +108,urn:mavedb:00000061-f-1,TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAAGAACAGTGGTCAATGTGCGAAATGGAATGAGCTTGCATGACTGCCTTATGAAAGCACTCAAGGTGAGGGGC,dna,RAF,GCF_000001405.26,P04049,Protein coding +109,urn:mavedb:00000001-a-2,ATGTCGGGGATCGCCCTCAGCAGACTCGCCCAGGAGAGGAAAGCATGGAGGAAAGACCACCCATTTGGTTTCGTGGCTGTCCCAACAAAAAATCCCGATGGCACGATGAACCTCATGAACTGGGAGTGCGCCATTCCAGGAAAGAAAGGGACTCCGTGGGAAGGAGGCTTGTTTAAACTACGGATGCTTTTCAAAGATGATTATCCATCTTCGCCACCAAAATGTAAATTCGAACCACCATTATTTCACCCGAATGTGTACCCTTCGGGGACAGTGTGCCTGTCCATCTTAGAGGAGGACAAGGACTGGAGGCCAGCCATCACAATCAAACAGATCCTATTAGGAATACAGGAACTTCTAAATGAACCAAATATCCAAGACCCAGCTCAAGCAGAGGCCTACACGATTTACTGCCAAAACAGAGTGGAGTACGAGAAAAGGGTCCGAGCACAAGCCAAGAAGTTTGCGCCCTCATAA,dna,UBE2I,GCF_000001405.26,P63279,Protein coding +110,urn:mavedb:00000083-d-1,AGTTAGGGATGGGAGCTCCAGCACAGTGAAATGGACAGAAGGGCAGAGCAA,dna,Minigene exon - hnRNPA1 binding site,GCF_000001405.13,,Other noncoding +111,urn:mavedb:00000003-b-2,GATTTATCTGCTCTTCGCGTTGAAGAAGTACAAAATGTCATTAATGCTATGCAGAAAATCTTAGAGTGTCCCATCTGCCTGGAGTTGATCAAGGAACCTGTCTCCACAAAGTGTGACCACATATTTTGCAAATTTTGCATGCTGAAACTTCTCAACCAGAAGAAAGGGCCTTCACAGTGTCCTTTATGTAAGAATGATATAACCAAAAGGAGCCTACAAGAAAGTACGAGATTTAGTCAACTTGTTGAAGAGCTATTGAAAATCATTTGTGCTTTTCAGCTTGACACAGGTTTGGAGTATGCAAACAGCTATAATTTTGCAAAAAAGGAAAATAACTCTCCTGAACATCTAAAAGATGAAGTTTCTATCATCCAAAGTATGGGCTACAGAAACCGTGCCAAAAGACTTCTACAGAGTGAACCCGAAAATCCTTCCTTGCAGGAAACCAGTCTCAGTGTCCAACTCTCTAACCTTGGAACTGTGAGAACTCTGAGGACAAAGCAGCGGATACAACCTCAAAGGACGTCTGTCTACATTGAATTGGGATCTGATTCTTCTGAAGATACCGTTAATAAGGCAACTTATTGCAGTGTGGGAGATCAAGAATTGTTACAAATCACCCCTCAAGGAACCAGGGATGAAATCAGTTTGGATTCTGCAAAAAAGGCTGCTTGTGAATTTTCTGAGACGGATGTAACAAATACTGAACATCATCAACCCAGTAATAATGATTTGAACACCACTGAGAAGCGTGCAGCTGAGAGGCATCCAGAAAAGTATCAGGGTAGTTCTGTTTCAAACTTGCATGTGGAGCCATGTGGCACAAATACTCATGCCAGCTCATTACAGCATGAGAACAGCAGTTTATTACTCACTAAAGACAGAATGAATGTAGAAAAGGCTGAGTTC,dna,BRCA1 RING domain,GCF_000001405.26,,Protein coding +112,urn:mavedb:00000027-a-1,TGCTTTCAGTGTGGGCCTGGGGCTGCGGGACCATGGAATGAGAGGGAGAGGATGACAAAACTGCTGGTCTTATCTAAGGGAGACAGAGAAGAGAAAAGGGGCACACCCAGTAGGCCACCCTGTCCCCACAGAATCCCTCCCCCAGAACGGCCTGCTCTCTGCCCTCATCTCCTGGCATTTCCTCTCATCCTTTTTTCCTGATAAATTTTCAATCCATTCATACTATCTGGTCATCCACGTGAATAGATATTTTTTTTTTGGCCAGTCATATGGCCCCATTTTCTTTGTACTTTACTGAAGTTAGCTCTAGTGAATCCAGGGAGCAGGGGCTGTAGGGTGGGGCTGGAGCCTGAAGAAAGACAAAAGGGATCACTGTGATAATATGGTGGGGGGAGGGTTACCCAGTTCTGACCACTTTTTTTCTCTGTCTCAACCAAGAAATGCAGAGTGCCTTCACCACTCTGTAACCT,dna,PKLR promoter,GCF_000001405.26,,Regulatory +113,urn:mavedb:00000062-a-1,TCTCTTGTGGTCCTTGTGCTCTGTCTCTCATGTTTGCTTCTCCTTTCACTCTGGAGACAGAGCTCTGGGAGAGGAAAACTCCCTCCTGGCCCCACTCCTCTCCCAGTGATTGGAAATATCCTACAGATAGGTATTAAGGACATCAGCAAATCCTTAACCAATCTCTCAAAGGTCTATGGCCCTGTGTTCACTCTGTATTTTGGCCTGAAACCCATAGTGGTGCTGCATGGATATGAAGCAGTGAAGGAAGCCCTGATTGATCTTGGAGAGGAGTTTTCTGGAAGAGGCATTTTCCCACTGGCTGAAAGAGCTAACAGAGGATTTGGAATTGTTTTCAGCAATGGAAAGAAATGGAAGGAGATCCGGCGTTTCTCCCTCATGACGCTGCGGAATTTTGGGATGGGGAAGAGGAGCATTGAGGACCGTGTTCAAGAGGAAGCCCGCTGCCTTGTGGAGGAGTTGAGAAAAACCAAGGCCTCACCCTGTGATCCCACTTTCATCCTGGGCTGTGCTCCCTGCAATGTGATCTGCTCCATTATTTTCCATAAACGTTTTGATTATAAAGATCAGCAATTTCTTAACTTAATGGAAAAGTTGAATGAAAACATCAAGATTTTGAGCAGCCCCTGGATCCAGATCTGCAATAATTTTTCTCCTATCATTGATTACTTCCCGGGAACTCACAACAAATTACTTAAAAACGTTGCTTTTATGAAAAGTTATATTTTGGAAAAAGTAAAAGAACACCAAGAATCAATGGACATGAACAACCCTCAGGACTTTATTGATTGCTTCCTGATGAAAATGGAGAAGGAAAAGCACAACCAACCATCTGAATTTACTATTGAAAGCTTGGAAAACACTGCAGTTGACTTGTTTGGAGCTGGGACAGAGACGACAAGCACAACCCTGAGATATGCTCTCCTTCTCCTGCTGAAGCACCCAGAGGTCACAGCTAAAGTCCAGGAAGAGATTGAACGTGTGATTGGCAGAAACCGGAGCCCCTGCATGCAAGACAGGAGCCACATGCCCTACACAGATGCTGTGGTGCACGAGGTCCAGAGATACATTGACCTTCTCCCCACCAGCCTGCCCCATGCAGTGACCTGTGACATTAAATTCAGAAACTATCTCATTCCCAAGGGCACAACCATATTAATTTCCCTGACTTCTGTGCTACATGACAACAAAGAATTTCCCAACCCAGAGATGTTTGACCCTCATCACTTTCTGGATGAAGGTGGCAATTTTAAGAAAAGTAAATACTTCATGCCTTTCTCAGCAGGAAAACGGATTTGTGTGGGAGAAGCCCTGGCCGGCATGGAGCTGTTTTTATTCCTGACCTCCATTTTACAGAACTTTAACCTGAAATCTCTGGTTGACCCAAAGAACCTTGACACCACTCCAGTTGTCAATGGATTTGCCTCTGTGCCGCCCTTCTACCAGCTGTGCTTCATTCCT,dna,CYP2C9,GCF_000001405.26,P11712,Protein coding +114,urn:mavedb:00000097-e-1,TATAATTTATAGATTTTGCATGCTGAAACTTCTCAACCAGAAGAAAGGGCCTTCACAGTGTCCTTTATGTAAGAATGATATAACCAAAAGGTATATAATT,dna,BRCA1 Exon 4,GCF_000001405.13,,Protein coding +115,urn:mavedb:00000005-a-5,ATGCCTTCTGAGACCCCCCAGGCAGAAGTGGGGCCCACAGGCTGCCCCCACCGCTCAGGGCCACACTCGGCGAAGGGGAGCCTGGAGAAGGGGTCCCCAGAGGATAAGGAAGCCAAGGAGCCCCTGTGGATCCGGCCCGATGCTCCGAGCAGGTGCACCTGGCAGCTGGGCCGGCCTGCCTCCGAGTCCCCACATCACCACACTGCCCCGGCAAAATCTCCAAAAATCTTGCCAGATATTCTGAAGAAAATCGGGGACACCCCTATGGTCAGAATCAACAAGATTGGGAAGAAGTTCGGCCTGAAGTGTGAGCTCTTGGCCAAGTGTGAGTTCTTCAACGCGGGCGGGAGCGTGAAGGACCGCATCAGCCTGCGGATGATTGAGGATGCTGAGCGCGACGGGACGCTGAAGCCCGGGGACACGATTATCGAGCCGACATCCGGGAACACCGGGATCGGGCTGGCCCTGGCTGCGGCAGTGAGGGGCTATCGCTGCATCATCGTGATGCCAGAGAAGATGAGCTCCGAGAAGGTGGACGTGCTGCGGGCACTGGGGGCTGAGATTGTGAGGACGCCCACCAATGCCAGGTTCGACTCCCCGGAGTCACACGTGGGGGTGGCCTGGCGGCTGAAGAACGAAATCCCCAATTCTCACATCCTAGACCAGTACCGCAACGCCAGCAACCCCCTGGCTCACTACGACACCACCGCTGATGAGATCCTGCAGCAGTGTGATGGGAAGCTGGACATGCTGGTGGCTTCAGTGGGCACGGGCGGCACCATCACGGGCATTGCCAGGAAGCTGAAGGAGAAGTGTCCTGGATGCAGGATCATTGGGGTGGATCCCGAAGGGTCCATCCTCGCAGAGCCGGAGGAGCTGAACCAGACGGAGCAGACAACCTACGAGGTGGAAGGGATCGGCTACGACTTCATCCCCACGGTGCTGGACAGGACGGTGGTGGACAAGTGGTTCAAGAGCAACGATGAGGAGGCGTTCACCTTTGCCCGCATGCTGATCGCGCAAGAGGGGCTGCTGTGCGGTGGCAGTGCTGGCAGCACGGTGGCGGTGGCCGTGAAGGCCGCGCAGGAGCTGCAGGAGGGCCAGCGCTGCGTGGTCATTCTGCCCGACTCAGTGCGGAACTACATGACCAAGTTCCTGAGCGACAGGTGGATGCTGCAGAAGGGCTTTCTGAAGGAGGAGGACCTCACGGAGAAGAAGCCCTGGTGGTGGCACCTCCGTGTTCAGGAGCTGGGCCTGTCAGCCCCGCTGACCGTGCTCCCGACCATCACCTGTGGGCACACCATCGAGATCCTCCGGGAGAAGGGCTTCGACCAGGCGCCCGTGGTGGATGAGGCGGGGGTAATCCTGGGAATGGTGACGCTTGGGAACATGCTCTCGTCCCTGCTTGCCGGGAAGGTGCAGCCGTCAGACCAAGTTGGCAAAGTCATCTACAAGCAGTTCAAACAGATCCGCCTCACGGACACGCTGGGCAGGCTCTCGCACATCCTGGAGATGGACCACTTCGCCCTGGTGGTGCACGAGCAGATCCAGTACCACAGCACCGGGAAGTCCAGTCAGCGGCAGATGGTGTTCGGGGTGGTCACCGCCATTGACTTGCTGAACTTCGTGGCCGCCCAGGAGCGGGACCAGAAGTGA,dna,CBS,GCF_000001405.26,P35520,Protein coding +116,urn:mavedb:00000033-a-1,GTTCATGTTTCCCCCGTATGTGCGTGCGCATGCACATATATAAACACATCTAGCTTCACACCTGTGTACTCACACCTGTGTGTACACACTCCTCCTGTACATGTGTATACACGCACACCCTCCCACCAGCATGAGCAGTATGTGGATTTTTTCTTCCAGCAGCCCTTTCAAGAACATACACCAGATGGGATTGGGTCTGCTACATGACTGAGCAGCCCCCACATCAGAAAGTCATCATCATTGAATCCATCATGTGGTGCAGCCTTGGCAAGGGCACAGCTCCTCGTCCTGCCCAATGGGCCGTGGAGGAATGCCTCCTCCTCCAGAGCAGAGAGCAGATATGGGCAGGCAGTTGCCAGGCAGTTGAGCCGGGAGAACAGATGGCAGCTGCACAGCCTCCTTCTAGCCCAGTTTCCTGGCTGCCGGGGAAGGAGTTGCAGGCGGCAAGGATCCTGCAGAAACCGCCCTCCCTATAACAGGCCATCTTGCCCTCTATCCTCTTACTGGGCTTTGGAGGTCCCAATCCTGCCCTGGTTCACCACCTGTGTGGCTTACCAAGCTGTGCAACTTGGGGCAGGA,dna,ZFAND3 enhancer,GCF_000001405.26,,Regulatory +117,urn:mavedb:00000057-d-1,ACGGAATATAAGCTGGTGGTGGTGGGCGCCGGCGGTGTGGGCAAGAGTGCGCTGACCATCCAGCTGATCCAGAACCATTTTGTGGACGAATACGACCCCACTATAGAGGATTCCTACCGGAAGCAGGTGGTCATTGATGGGGAGACGTGCCTGTTGGACATCCTGGATACCGCCGGCCAGGAGGAGTACAGCGCCATGCGGGACCAGTACATGCGCACCGGGGAGGGCTTCCTGTGTGTGTTTGCCATCAACAACACCAAGTCTTTTGAGGACATCCACCAGTACAGGGAGCAGATCAAACGGGTGAAGGACTCGGATGACGTGCCCATGGTGCTGGTGGGGAACAAGTGTGACCTGGCTGCACGCACTGTGGAATCTCGGCAGGCTCAGGACCTCGCCCGAAGCTACGGCATCCCCTACATCGAGACCTCGGCCAAGACCCGGCAGGGAGTGGAGGATGCCTTCTACACGTTGGTGCGTGAGATCCGGCAGCAC,dna,Ras,GCF_000001405.26,P01112,Protein coding +118,urn:mavedb:00000068-a-1,ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAACGTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCAGATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCGCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCCTGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAGTCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACACCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAGCGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAACACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGTTCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGTGGTAATCTACTGGGACGGAACAGCTTTGAGGTGCGTGTTTGTGCCTGTCCTGGGAGAGACCGGCGCACAGAGGAAGAGAATCTCCGCAAGAAAGGGGAGCCTCACCACGAGCTGCCCCCAGGGAGCACTAAGCGAGCACTGCCCAACAACACCAGCTCCTCTCCCCAGCCAAAGAAGAAACCACTGGATGGAGAATATTTCACCCTTCAGATCCGTGGGCGTGAGCGCTTCGAGATGTTCCGAGAGCTGAATGAGGCCTTGGAACTCAAGGATGCCCAGGCTGGGAAGGAGCCAGGGGGGAGCAGGGCTCACTCCAGCCACCTGAAGTCCAAAAAGGGTCAGTCTACCTCCCGCCATAAAAAACTCATGTTCAAGACAGAAGGGCCTGACTCAGACTAG,dna,TP53 (P72R),GCF_000001405.26,,Protein coding +119,urn:mavedb:00000049-a-6,ATGGTGAACGAAGCCAGAGGAAACAGCAGCCTCAACCCCTGCTTGGAGGGCAGTGCCAGCAGTGGCAGTGAGAGCTCCAAAGATAGTTCGAGATGTTCCACCCCGGGCCTGGACCCCGAGCGGCATGAGAGACTCCGGGAGAAGATGAGGCGGCGATTGGAATCTGGTGACAAGTGGTTCTCCCTGGAATTCTTCCCTCCTCGAACTGCTGAGGGAGCTGTCAATCTCATCTCAAGGTTTGACCGGATGGCAGCAGGTGGCCCCCTCTACATAGACGTGACCTGGCACCCAGCAGGTGACCCTGGCTCAGACAAGGAGACCTCCTCCATGATGATCGCCAGCACCGCCGTGAACTACTGTGGCCTGGAGACCATCCTGCACATGACCTGCTGCCGTCAGCGCCTGGAGGAGATCACGGGCCATCTGCACAAAGCTAAGCAGCTGGGCCTGAAGAACATCATGGCGCTGCGGGGAGACCCAATAGGTGACCAGTGGGAAGAGGAGGAGGGAGGCTTCAACTACGCAGTGGACCTGGTGAAGCACATCCGAAGTGAGTTTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCGAAGCAGGGAGCTTTGAGGCTGACCTGAAGCACTTGAAGGAGAAGGTGTCTGCGGGAGCCGATTTCATCATCACGCAGCTTTTCTTTGAGGCTGACACATTCTTCCGCTTTGTGAAGGCATGCACCGACATGGGCATCACTTGCCCCATCGTCCCCGGGATCTTTCCCATCCAGGGCTACCACTCCCTTCGGCAGCTTGTGAAGCTGTCCAAGCTGGAGGTGCCACAGGAGATCAAGGACGTGATTGAGCCAATCAAAGACAACGATGCTGCCATCCGCAACTATGGCATCGAGCTGGCCGTGAGCCTGTGCCAGGAGCTTCTGGCCAGTGGCTTGGTGCCAGGCCTCCACTTCTACACCCTCAACCGCGAGATGGCTACCACAGAGGTGCTGAAGCGCCTGGGGATGTGGACTGAGGACCCCAGGCGTCCCCTACCCTGGGCTCTCAGCGCCCACCCCAAGCGCCGAGAGGAAGATGTACGTCCCATCTTCTGGGCCTCCAGACCAAAGAGTTACATCTACCGTACCCAGGAGTGGGACGAGTTCCCTAACGGCCGCTGGGGCAATTCCTCTTCCCCTGCCTTTGGGGAGCTGAAGGACTACTACCTCTTCTACCTGAAGAGCAAGTCCCCCAAGGAGGAGCTGCTGAAGATGTGGGGGGAGGAGCTGACCAGTGAAGAAAGTGTCTTTGAAGTCTTCGTTCTTTACCTCTCGGGAGAACCAAACCGGAATGGTCACAAAGTGACTTGCCTGCCCTGGAACGATGAGCCCCTGGCGGCTGAGACCAGCCTGCTGAAGGAGGAGCTGCTGCGGGTGAACCGCCAGGGCATCCTCACCATCAACTCACAGCCCAACATCAACGGGAAGCCGTCCTCCGACCCCATCGTGGGCTGGGGCCCCAGCGGGGGCTATGTCTTCCAGAAGGCCTACTTAGAGTTTTTCACTTCCCGCGAGACAGCGGAAGCACTTCTGCAAGTGCTGAAGAAGTACGAGCTCCGGGTTAATTACCACCTTGTCAATGTGAAGGGTGAAAACATCACCAATGCCCCTGAACTGCAGCCGAATGCTGTCACTTGGGGCATCTTCCCTGGGCGAGAGATCATCCAGCCCACCGTAGTGGATCCCGTCAGCTTCATGTTCTGGAAGGACGAGGCCTTTGCCCTGTGGATTGAGCGGTGGGGAAAGCTGTATGAGGAGGAGTCCCCGTCCCGCACCATCATCCAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAATGACTTCCCACTGGACAACTGCCTCTGGCAGGTGGTGGAAGACACATTGGAGCTTCTCAACAGGCCCACCCAGAATGCGAGAGAAACGGAGGCTCCATGA,dna,MTHFR,GCF_000001405.26,P42898,Protein coding +120,urn:mavedb:00000104-a-1,CGGTGGCCGGTGCGGCGTGTTCGGTGGCGGCTCTGGCCGCTCAGGCGCCTGCGGCTGGGTGAGCGCACGCGAGGCGGCGAGGCGGCAGCGTGTTTCTAGGTCGTGGCGTCGGGCTTCCGGAGCTTTGGCGGCAGCTAGGGGAGGATGGCGGAGTCTTCGGATAAGCTCTATCGAGTCGAGTACGCCAAGAGCGGGCGCGCCTCTTGCAAGAAATGCAGCGAGAGCATCCCCAAGGACTCGCTCCGGATGGCCATCATGGTGCAGTCGCCCATGTTTGATGGAAAAGTCCCACACTGGTACCACTTCTCCTGCTTCTGGAAGGTGGGCCACTCCATCCGGCACCCTGACGTTGAGGTGGATGGGTTCTCTGAGCTTCGGTGGGATGACCAGCAGAAAGTCAAGAAGACAGCGGAAGCTGGAGGAGTGACAGGCAAAGGCCAGGATGGAATTGGTAGCAAGGCAGAGAAGACTCTGGGTGACTTTGCAGCAGAGTATGCCAAGTCCAACAGAAGTACGTGCAAGGGGTGTATGGAGAAGATAGAAAAGGGCCAGGTGCGCCTGTCCAAGAAGATGGTGGACCCGGAGAAGCCACAGCTAGGCATGATTGACCGCTGGTACCATCCAGGCTGCTTTGTCAAGAACAGGGAGGAGCTGGGTTTCCGGCCCGAGTACAGTGCGAGTCAGCTCAAGGGCTTCAGCCTCCTTGCTACAGAGGATAAAGAAGCCCTGAAGAAGCAGCTCCCAGGAGTCAAGAGTGAAGGAAAGAGAAAAGGCGATGAGGTGGATGGAGTGGATGAAGTGGCGAAGAAGAAATCTAAAAAAGAAAAAGACAAGGATAGTAAGCTTGAAAAAGCCCTAAAGGCTCAGAACGACCTGATCTGGAACATCAAGGACGAGCTAAAGAAAGTGTGTTCAACTAATGACCTGAAGGAGCTACTCATCTTCAACAAGCAGCAAGTGCCTTCTGGGGAGTCGGCGATCTTGGACCGAGTAGCTGATGGCATGGTGTTCGGTGCCCTCCTTCCCTGCGAGGAATGCTCGGGTCAGCTGGTCTTCAAGAGCGATGCCTATTACTGCACTGGGGACGTCACTGCCTGGACCAAGTGTATGGTCAAGACACAGACACCCAACCGGAAGGAGTGGGTAACCCCAAAGGAATTCCGAGAAATCTCTTACCTCAAGAAATTGAAGGTTAAAAAACAGGACCGTATATTCCCCCCAGAAACCAGCGCCTCCGTGGCGGCCACGCCTCCGCCCTCCACAGCCTCGGCTCCTGCTGCTGTGAACTCCTCTGCTTCAGCAGATAAGCCATTATCCAACATGAAGATCCTGACTCTCGGGAAGCTGTCCCGGAACAAGGATGAAGTGAAGGCCATGATTGAGAAACTCGGGGGGAAGTTGACGGGGACGGCCAACAAGGCTTCCCTGTGCATCAGCACCAAAAAGGAGGTGGAAAAGATGAATAAGAAGATGGAGGAAGTAAAGGAAGCCAACATCCGAGTTGTGTCTGAGGACTTCCTCCAGGACGTCTCCGCCTCCACCAAGAGCCTTCAGGAGTTGTTCTTAGCGCACATCTTGTCCCCTTGGGGGGCAGAGGTGAAGGCAGAGCCTGTTGAAGTTGTGGCCCCAAGAGGGAAGTCAGGGGCTGCGCTCTCCAAAAAAAGCAAGGGCCAGGTCAAGGAGGAAGGTATCAACAAATCTGAAAAGAGAATGAAATTAACTCTTAAAGGAGGAGCAGCTGTGGATCCTGATTCTGGACTGGAACACTCTGCGCATGTCCTGGAGAAAGGTGGGAAGGTCTTCAGTGCCACCCTTGGCCTGGTGGACATCGTTAAAGGAACCAACTCCTACTACAAGCTGCAGCTTCTGGAGGACGACAAGGAAAACAGGTATTGGATATTCAGGTCCTGGGGCCGTGTGGGTACGGTGATCGGTAGCAACAAACTGGAACAGATGCCGTCCAAGGAGGATGCCATTGAGCACTTCATGAAATTATATGAAGAAAAAACCGGGAACGCTTGGCACTCCAAAAATTTCACGAAGTATCCCAAAAAGTTCTACCCCCTGGAGATTGACTATGGCCAGGATGAAGAGGCAGTGAAGAAGCTGACAGTAAATCCTGGCACCAAGTCCAAGCTCCCCAAGCCAGTTCAGGACCTCATCAAGATGATCTTTGATGTGGAAAGTATGAAGAAAGCCATGGTGGAGTATGAGATCGACCTTCAGAAGATGCCCTTGGGGAAGCTGAGCAAAAGGCAGATCCAGGCCGCATACTCCATCCTCAGTGAGGTCCAGCAGGCGGTGTCTCAGGGCAGCAGCGACTCTCAGATCCTGGATCTCTCAAATCGCTTTTACACCCTGATCCCCCACGACTTTGGGATGAAGAAGCCTCCGCTCCTGAACAATGCAGACAGTGTGCAGGCCAAGGTGGAAATGCTTGACAACCTGCTGGACATCGAGGTGGCCTACAGTCTGCTCAGGGGAGGGTCTGATGATAGCAGCAAGGATCCCATCGATGTCAACTATGAGAAGCTCAAAACTGACATTAAGGTGGTTGACAGAGATTCTGAAGAAGCCGAGATCATCAGGAAGTATGTTAAGAACACTCATGCAACCACACACAATGCGTATGACTTGGAAGTCATCGATATCTTTAAGATAGAGCGTGAAGGCGAATGCCAGCGTTACAAGCCCTTTAAGCAGCTTCATAACCGAAGATTGCTGTGGCACGGGTCCAGGACCACCAACTTTGCTGGGATCCTGTCCCAGGGTCTTCGGATAGCCCCGCCTGAAGCGCCCGTGACAGGCTACATGTTTGGTAAAGGGATCTATTTCGCTGACATGGTCTCCAAGAGTGCCAACTACTGCCATACGTCTCAGGGAGACCCAATAGGCTTAATCCTGTTGGGAGAAGTTGCCCTTGGAAACATGTATGAACTGAAGCACGCTTCACATATCAGCAAGTTACCCAAGGGCAAGCACAGTGTCAAAGGTTTGGGCAAAACTACCCCTGATCCTTCAGCTAACATTAGTCTGGATGGTGTAGACGTTCCTCTTGGGACCGGGATTTCATCTGGTGTGAATGACACCTCTCTACTATATAACGAGTACATTGTCTATGATATTGCTCAGGTAAATCTGAAGTATCTGCTGAAACTGAAATTCAATTTTAAGACCTCCCTGTGGTAATTGGGAGAGGTAGCCGAGTCACACCCGGTGGCTCTGGTATGAATTCACCCGAAGCGCTTCTGCACCAACTCACCTGGCCGCTAAGTTGCTGATGGGTAGTACCTGTACTAAACCACCTCAGAAAGGATTTTACAGAAACGTGTTAAAGGTTTTCTCTAACTTCTCAAGTCCCTTGTTTTGTGTTGTGTCTGTGGGGAGGGGTTGTTTTGGGGTTGTTTTTGTTTTTTCTTGCCAGGTAGATAAAACTGACATAGAGAAAAGGCTGGAGAGAGATTCTGTTGCATAGACTAGTCCTATGGAAAAAACCAAGCTTCGTTAGAATGTCTGCCTTACTGGTTTCCCCAGGGAAGGAAAAATACACTTCCACCCTTTTTTCTAAGTGTTCGTCTTTAGTTTTGATTTTGGAAAGATGTTAAGCATTTATTTTTAGTTAAAAATAAAAACTAATTTCATACTATTTAGATTTTCTTTTTTATCTTGCACTTATTGTCCCCTTTTTAGTTTTTTTTGTTTGCCTCTTGTGGTGAGGGGTGTGGGAAGACCAAAGGAAGGAACGCTAACAATTTCTCATACTTAGAAACAAAAAGAGCTTTCCTTCTCCAGGAATACTGAACATGGGAGCTCTTGAAATATGTAGTATTAAAAGTTGCATTTGAAATTCTTGACTTTCTTATGGGCACTTTTGTCTTCCAAATTAAAACTCTACCACAAATATACTTACCCAAGGGCTAATAGTAATACTCGATTAAAAATGCAGATGCCTTCTCTA,dna,PARP1,GCF_000001405.26,,Protein coding +121,urn:mavedb:00000083-c-1,AGTTGACGACGGGAGCTCCAGCACAGTGAAATGGACAGAAGGGCAGAGCAA,dna,Minigene exon - SRSF7 (9G8) binding site,GCF_000001405.13,,Other noncoding +122,urn:mavedb:00000049-a-1,ATGGTGAACGAAGCCAGAGGAAACAGCAGCCTCAACCCCTGCTTGGAGGGCAGTGCCAGCAGTGGCAGTGAGAGCTCCAAAGATAGTTCGAGATGTTCCACCCCGGGCCTGGACCCCGAGCGGCATGAGAGACTCCGGGAGAAGATGAGGCGGCGATTGGAATCTGGTGACAAGTGGTTCTCCCTGGAATTCTTCCCTCCTCGAACTGCTGAGGGAGCTGTCAATCTCATCTCAAGGTTTGACCGGATGGCAGCAGGTGGCCCCCTCTACATAGACGTGACCTGGCACCCAGCAGGTGACCCTGGCTCAGACAAGGAGACCTCCTCCATGATGATCGCCAGCACCGCCGTGAACTACTGTGGCCTGGAGACCATCCTGCACATGACCTGCTGCCGTCAGCGCCTGGAGGAGATCACGGGCCATCTGCACAAAGCTAAGCAGCTGGGCCTGAAGAACATCATGGCGCTGCGGGGAGACCCAATAGGTGACCAGTGGGAAGAGGAGGAGGGAGGCTTCAACTACGCAGTGGACCTGGTGAAGCACATCCGAAGTGAGTTTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCGAAGCAGGGAGCTTTGAGGCTGACCTGAAGCACTTGAAGGAGAAGGTGTCTGCGGGAGCCGATTTCATCATCACGCAGCTTTTCTTTGAGGCTGACACATTCTTCCGCTTTGTGAAGGCATGCACCGACATGGGCATCACTTGCCCCATCGTCCCCGGGATCTTTCCCATCCAGGGCTACCACTCCCTTCGGCAGCTTGTGAAGCTGTCCAAGCTGGAGGTGCCACAGGAGATCAAGGACGTGATTGAGCCAATCAAAGACAACGATGCTGCCATCCGCAACTATGGCATCGAGCTGGCCGTGAGCCTGTGCCAGGAGCTTCTGGCCAGTGGCTTGGTGCCAGGCCTCCACTTCTACACCCTCAACCGCGAGATGGCTACCACAGAGGTGCTGAAGCGCCTGGGGATGTGGACTGAGGACCCCAGGCGTCCCCTACCCTGGGCTCTCAGCGCCCACCCCAAGCGCCGAGAGGAAGATGTACGTCCCATCTTCTGGGCCTCCAGACCAAAGAGTTACATCTACCGTACCCAGGAGTGGGACGAGTTCCCTAACGGCCGCTGGGGCAATTCCTCTTCCCCTGCCTTTGGGGAGCTGAAGGACTACTACCTCTTCTACCTGAAGAGCAAGTCCCCCAAGGAGGAGCTGCTGAAGATGTGGGGGGAGGAGCTGACCAGTGAAGAAAGTGTCTTTGAAGTCTTCGTTCTTTACCTCTCGGGAGAACCAAACCGGAATGGTCACAAAGTGACTTGCCTGCCCTGGAACGATGAGCCCCTGGCGGCTGAGACCAGCCTGCTGAAGGAGGAGCTGCTGCGGGTGAACCGCCAGGGCATCCTCACCATCAACTCACAGCCCAACATCAACGGGAAGCCGTCCTCCGACCCCATCGTGGGCTGGGGCCCCAGCGGGGGCTATGTCTTCCAGAAGGCCTACTTAGAGTTTTTCACTTCCCGCGAGACAGCGGAAGCACTTCTGCAAGTGCTGAAGAAGTACGAGCTCCGGGTTAATTACCACCTTGTCAATGTGAAGGGTGAAAACATCACCAATGCCCCTGAACTGCAGCCGAATGCTGTCACTTGGGGCATCTTCCCTGGGCGAGAGATCATCCAGCCCACCGTAGTGGATCCCGTCAGCTTCATGTTCTGGAAGGACGAGGCCTTTGCCCTGTGGATTGAGCGGTGGGGAAAGCTGTATGAGGAGGAGTCCCCGTCCCGCACCATCATCCAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAATGACTTCCCACTGGACAACTGCCTCTGGCAGGTGGTGGAAGACACATTGGAGCTTCTCAACAGGCCCACCCAGAATGCGAGAGAAACGGAGGCTCCATGA,dna,MTHFR,GCF_000001405.26,P42898,Protein coding +123,urn:mavedb:00000028-a-1,CAGAGGCACCAGGGTCAAAGCCAGTGGTGATGCCCTGGCCCCGTTGCCCCAGGCCAGGGCCAGTGAACAATGTAATCAGCTGGGGCAGACTCTACAGCCCTGCAGCCAAGGGGGCCAGTGACCCTTACATGGTCATCCACAGGCCACTTGGGTGGCCAGTCCTGTTCAGCCAGGCCTTGCCCTAGGAAAGAAATTAATTATAACCTAATTGGCAGTTTCCTTTGCATAGAAGCCGGAAGCAACTGCCAGTGAGGCTGGTGATTAACTCTGCAGCAGCTGGGAAATTGCAGTTGGGCAGGAGCGCCCATCATCCTGGCCAGGCCGCTGCAGCTGGTCTGGGTATGGAAGTGTGGGTGGTGGCCATCGTGCAGCTTAGGGCCTGGGCCCCTCAGAGCAGAAGGCTGGGTCTGTGTGCAGAAGGTAGCCTTGGGCTGCCAGGTCCCCCAGTGCCCAGTTGCGGACCTCCTTCTCCCAAACCTCAGCCATGCCTGGACCCCTTCCCCACTCACGGCAGAAGGCTGCATGGCTTTTAGGGGTGTCAGGAGGCTCATGTCCTGGTTGCAGTTCTACCATGGGTGTGCAGCGGGAATTCTGGGCTTC,dna,RET enhancer,GCF_000001405.26,,Regulatory +124,urn:mavedb:00000029-a-1,GAACTGGAAAAGCCCTGTCCGGTGAGGGGGCAGAAGGACTCAGCGCCCCTGGACCCCCAAATGCTGCATGAACACATTTTCAGGGGAGCCTGTGCCCCCAGGCGGGGGTCGGGCAGCCCCAGCCCCTCTCCTTTTCCTGGACTCTGGCCGTGCGCGGCAGCCCAGGTGTTTGCTCAGTTGCTGACCCAAAAGTGCTTCATTTTTCGTGCCCGCCCCGCGCCCCGGGCAGGCCAGTCATGTGTTAAGTTGCGCTTCTTTGCTGTGATGTGGGTGGGGGAGGAAGAGTAAACACAGTGCTGGCTCGGCTGCCCTGAGGGTGCTCAATCAAGCACAGGTTTCAAGTCTGGGTTCTGGTGTCCACTCACCCACCCCACCCCCCAAAATCAGACAAATGCTACTTTGTCTAACCTGCTGTGGCCTCTGAGACATGTTCTATTTTTAACCCCTTCTTGGAATTGGCTCTCTTCTTCAAAGGACCAGGTCCTGTTCCTCTTTCTCCCCGACTCCACCCCAGCTCCCTGTGAAGAGAGAGTTAATATATTTGTTTTATTTATTTGCTTTTTGTGTTGGGATGGGTTCGTGTCCAGTCCCGGGGGTCTG,dna,SORT1 enhancer,GCF_000001405.26,,Regulatory +125,urn:mavedb:00000013-b-1,ATGGATGGTACAAGAACTTCACTTGACATTGAAGAGTACTCGGATACTGAGGTACAGAAAAACCAAGTACTAACTCTGGAAGAATGGCAAGACAAGTGGGTGAACGGCAAGACTGCTTTTCATCAGGAACAAGGACATCAGCTATTAAAGAAGCATTTAGATACTTTCCTTAAAGGCAAGAGTGGACTGAGGGTATTTTTTCCTCTTTGCGGAAAAGCGGTTGAGATGAAATGGTTTGCAGACCGGGGACACAGTGTAGTTGGTGTGGAAATCAGTGAACTTGGGATACAAGAATTTTTTACAGAGCAGAATCTTTCTTACTCAGAAGAACCAATCACCGAAATTCCTGGAACCAAAGTATTTAAGAGTTCTTCGGGGAACATTTCATTGTACTGTTGCAGTATTTTTGATCTTCCCAGGACAAATATTGGCAAATTTGACATGATTTGGGATAGAGGAGCATTAGTTGCCATTAATCCAGGTGATCGCAAATGCTATGCAGATACAATGTTTTCCCTCCTGGGAAAGAAGTTTCAGTATCTCCTGTGTGTTCTTTCTTATGATCCAACTAAACATCCAGGTCCACCATTTTATGTTCCACATGCTGAAATTGAAAGGTTGTTTGGTAAAATATGCAATATACGTTGTCTTGAGAAGGTTGATGCTTTTGAAGAACGACATAAAAGTTGGGGAATTGACTGTCTTTTTGAAAAGTTATATCTACTTACAGAAAAGTAA,dna,TPMT,GCF_000001405.26,P51580,Protein coding +126,urn:mavedb:00000093-a-1,ATGGATTTATCTGCTCTTCGCGTTGAAGAAGTACAAAATGTCATTAATGCTATGCAGAAAATCTTAGAGTGTCCCATCTGTCTGGAGTTGATCAAGGAACCTGTCTCCACAAAGTGTGACCACATATTTTGCAAATTTTGCATGCTGAAACTTCTCAACCAGAAGAAAGGGCCTTCACAGTGTCCTTTATGTAAGAATGATATAACCAAAAGGAGCCTACAAGAAAGTACGAGATTTAGTCAACTTGTTGAAGAGCTATTGAAAATCATTTGTGCTTTTCAGCTTGACACAGGTTTGGAG,dna,BRCA1 translation start through RING domain,GCF_000001405.13,P38398,Protein coding +127,urn:mavedb:00000001-a-3,ATGTCGGGGATCGCCCTCAGCAGACTCGCCCAGGAGAGGAAAGCATGGAGGAAAGACCACCCATTTGGTTTCGTGGCTGTCCCAACAAAAAATCCCGATGGCACGATGAACCTCATGAACTGGGAGTGCGCCATTCCAGGAAAGAAAGGGACTCCGTGGGAAGGAGGCTTGTTTAAACTACGGATGCTTTTCAAAGATGATTATCCATCTTCGCCACCAAAATGTAAATTCGAACCACCATTATTTCACCCGAATGTGTACCCTTCGGGGACAGTGTGCCTGTCCATCTTAGAGGAGGACAAGGACTGGAGGCCAGCCATCACAATCAAACAGATCCTATTAGGAATACAGGAACTTCTAAATGAACCAAATATCCAAGACCCAGCTCAAGCAGAGGCCTACACGATTTACTGCCAAAACAGAGTGGAGTACGAGAAAAGGGTCCGAGCACAAGCCAAGAAGTTTGCGCCCTCATAA,dna,UBE2I,GCF_000001405.26,P63279,Protein coding +128,urn:mavedb:00000045-d-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +129,urn:mavedb:00000108-a-1,ATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGCATGAAGATGGCCCTGAGGATGACCCACAGTTGGTAGGCATCACTGCTCGTAACATTCCACGAGGGCCCCAGTTGGCTGCCCAGAACTTGGGCATCAGCCTGGCCAACTTGTTGCTGAGCAAAGGAGCCAAAAACATCCTGGATGTTGCACGGCAGCTTAACGATGCCCATTAA,dna,HMBS,GCF_000001405.26,P08397,Protein coding +130,urn:mavedb:00000096-a-1,ATGTTAGATGACAGAGCAAGAATGGAAGCAGCCAAGAAGGAAAAGGTAGAACAAATATTAGCAGAATTTCAATTACAAGAAGAAGATTTGAAGAAAGTTATGAGAAGAATGCAAAAGGAAATGGATAGAGGTTTGAGATTAGAAACTCATGAAGAAGCTTCTGTTAAGATGTTGCCAACTTACGTTAGATCTACACCAGAAGGTTCAGAAGTTGGTGACTTTTTGTCATTAGATTTGGGTGGTACTAACTTCAGAGTTATGTTGGTTAAGGTTGGTGAAGGTGAAGAAGGTCAATGGTCTGTTAAGACAAAGCATCAAATGTACTCAATCCCAGAAGATGCTATGACTGGTACAGCAGAAATGTTGTTCGATTACATCTCTGAATGTATCTCAGATTTCTTGGATAAGCATCAAATGAAGCATAAGAAATTGCCATTGGGTTTTACTTTTTCTTTCCCAGTTAGACATGAAGATATCGATAAGGGTATCTTGTTGAACTGGACAAAGGGTTTTAAAGCTTCAGGTGCAGAAGGTAATAATGTTGTTGGTTTGTTGAGAGATGCTATTAAAAGAAGAGGTGACTTTGAAATGGATGTTGTTGCTATGGTTAACGATACTGTTGCAACAATGATCTCTTGTTACTACGAAGATCATCAATGTGAAGTTGGTATGATTGTTGGTACTGGTTGTAACGCATGTTACATGGAAGAAATGCAAAACGTTGAATTGGTTGAAGGTGACGAAGGTAGAATGTGTGTTAATACAGAATGGGGTGCTTTTGGTGACTCTGGTGAATTGGATGAATTCTTGTTGGAATACGATAGATTGGTTGATGAATCTTCAGCAAATCCAGGTCAACAATTGTACGAAAAGTTGATCGGTGGTAAATACATGGGTGAATTAGTTAGATTGGTTTTGTTGAGATTGGTTGATGAAAATTTGTTGTTCCATGGTGAAGCTTCTGAACAATTGAGAACTAGAGGTGCATTCGAAACAAGATTCGTTTCTCAAGTTGAATCAGATACTGGTGACAGAAAGCAAATCTATAACATCTTGTCTACATTAGGTTTAAGACCATCAACTACAGATTGTGATATTGTTAGAAGAGCTTGTGAATCTGTTTCAACTAGAGCTGCACATATGTGTTCTGCTGGTTTGGCAGGTGTTATTAATAGAATGAGAGAATCTAGATCAGAAGATGTTATGAGAATCACAGTTGGTGTTGATGGTTCTGTTTACAAGTTGCATCCATCTTTTAAAGAAAGATTCCATGCATCTGTTAGAAGATTGACTCCATCATGTGAAATCACTTTTATTGAATCTGAAGAAGGTTCAGGTAGAGGTGCCGCTTTAGTCAGTGCTGTTGCTTGTAAGAAGGCTTGTATGTTGGGTCAATAG,dna,GCK,GCF_000001405.26,,Protein coding +131,urn:mavedb:00000003-a-2,GATTTATCTGCTCTTCGCGTTGAAGAAGTACAAAATGTCATTAATGCTATGCAGAAAATCTTAGAGTGTCCCATCTGCCTGGAGTTGATCAAGGAACCTGTCTCCACAAAGTGTGACCACATATTTTGCAAATTTTGCATGCTGAAACTTCTCAACCAGAAGAAAGGGCCTTCACAGTGTCCTTTATGTAAGAATGATATAACCAAAAGGAGCCTACAAGAAAGTACGAGATTTAGTCAACTTGTTGAAGAGCTATTGAAAATCATTTGTGCTTTTCAGCTTGACACAGGTTTGGAGTATGCAAACAGCTATAATTTTGCAAAAAAGGAAAATAACTCTCCTGAACATCTAAAAGATGAAGTTTCTATCATCCAAAGTATGGGCTACAGAAACCGTGCCAAAAGACTTCTACAGAGTGAACCCGAAAATCCTTCCTTGCAGGAAACCAGTCTCAGTGTCCAACTCTCTAACCTTGGAACTGTGAGAACTCTGAGGACAAAGCAGCGGATACAACCTCAAAGGACGTCTGTCTACATTGAATTGGGATCTGATTCTTCTGAAGATACCGTTAATAAGGCAACTTATTGCAGTGTGGGAGATCAAGAATTGTTACAAATCACCCCTCAAGGAACCAGGGATGAAATCAGTTTGGATTCTGCAAAAAAGGCTGCTTGTGAATTTTCTGAGACGGATGTAACAAATACTGAACATCATCAACCCAGTAATAATGATTTGAACACCACTGAGAAGCGTGCAGCTGAGAGGCATCCAGAAAAGTATCAGGGTAGTTCTGTTTCAAACTTGCATGTGGAGCCATGTGGCACAAATACTCATGCCAGCTCATTACAGCATGAGAACAGCAGTTTATTACTCACTAAAGACAGAATGAATGTAGAAAAGGCTGAGTTC,dna,BRCA1 RING domain,GCF_000001405.26,,Protein coding +132,urn:mavedb:00000097-c-1,TTTCTCCCCCCCTACCCTGCTAGTCTGGAGTTGATCAAGGAACCTGTCTCCACAAAGTGTGACCACATATTTTGCAAGTAAGTTTGAATGTGTTATGTGG,dna,BRCA1 Exon 3,GCF_000001405.13,,Protein coding +133,urn:mavedb:00000106-a-1,MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL,protein,AID,GCF_000001405.26,,Protein coding +134,urn:mavedb:00000083-g-1,AGTTCACACAGGGAGCTCCAGCACAGTGAAATGGACAGAAGGGCAGAGCAA,dna,Minigene exon - hnRNP L binding site,GCF_000001405.13,,Other noncoding +135,urn:mavedb:00000036-a-2,ATGGACGCGCTCAAGTCGGCGGGGCGGGCGCTGATCCGGAGCCCCAGCTTGGCCAAGCAGAGCTGGGGGGGCGGTGGCCGGCACCGCAAGCTGCCTGAGAACTGGACAGACACGCGGGAGACGCTGCTGGAGGGGATGCTGTTCAGCCTCAAGTACCTGGGCATGACGCTAGTGGAGCAGCCCAAGGGTGAGGAGCTGTCGGCCGCCGCCATCAAGAGGATCGTGGCTACAGCTAAGGCCAGTGGGAAGAAGCTGCAGAAGGTGACTCTGAAGGTGTCGCCACGGGGAATTATCCTGACAGACAACCTCACCAACCAGCTCATTGAGAACGTGTCCATATACAGGATCTCCTATTGCACAGCAGACAAGATGCACGACAAGGTGTTTGCATACATCGCCCAGAGCCAGCACAACCAGAGCCTCGAGTGCCACGCCTTCCTCTGCACCAAGCGGAAGATGGCACAGGCTGTTACCCTCACCGTAGCCCAGGCCTTCAAAGTCGCCTTTGAGTTTTGGCAGGTGTCCAAGGAAGAGAAAGAGAAGAGGGACAAAGCCAGCCAAGAGGGAGGGGACGTCCTGGGGGCCCGCCAAGACTGCACCCCCCCCTTGAAGAGCTTGGTCGCCACTGGGAACCTGCTGGACTTAGAGGAGACGGCTAAGGCCCCGCTGTCCACGGTCAGCGCCAACACCACCAACATGGACGAGGTGCCGCGGCCACAAGCCTTGAGTGGCAGCAGTGTTGTCTGGGAGCTGGATGATGGCCTGGATGAAGCGTTTTCGAGGCTTGCCCAGTCTCGGACAAACCCTCAGGTCCTGGACACTGGCCTGACAGCCCAGGACATGCATTACGCCCAGTGCCTCTCGCCTGTCGACTGGGACAAGCCTGACAGCAGCGGCACAGAGCAGGATGACCTCTTCAGCTTCTGA,dna,LDLRAP1,GCF_000001405.26,,Protein coding +136,urn:mavedb:00000097-t-1,CTCTCTTCCTCTCTTCTTCCAGATCTTCAGGGGGCTAGAAATCTGTTGCTATGGGCCCTTCACCAACATGCCCACAGGTAAGAGCCTGGGAGAACCCCAG,dna,BRCA1 Exon 20,GCF_000001405.13,,Protein coding +137,urn:mavedb:00000097-l-1,TTAATTTCAGATGCTCGTGTACAAGTTTGCCAGAAAACACCACATCACTTTAACTAATCTAATTACTGAAGAGACTACTCATGTTGTTATGAAAACAGGTATACCAAG,dna,BRCA1 Exon 16,GCF_000001405.13,,Protein coding +138,urn:mavedb:00000094-a-11,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +139,urn:mavedb:00000027-b-1,TGCTTTCAGTGTGGGCCTGGGGCTGCGGGACCATGGAATGAGAGGGAGAGGATGACAAAACTGCTGGTCTTATCTAAGGGAGACAGAGAAGAGAAAAGGGGCACACCCAGTAGGCCACCCTGTCCCCACAGAATCCCTCCCCCAGAACGGCCTGCTCTCTGCCCTCATCTCCTGGCATTTCCTCTCATCCTTTTTTCCTGATAAATTTTCAATCCATTCATACTATCTGGTCATCCACGTGAATAGATATTTTTTTTTTGGCCAGTCATATGGCCCCATTTTCTTTGTACTTTACTGAAGTTAGCTCTAGTGAATCCAGGGAGCAGGGGCTGTAGGGTGGGGCTGGAGCCTGAAGAAAGACAAAAGGGATCACTGTGATAATATGGTGGGGGGAGGGTTACCCAGTTCTGACCACTTTTTTTCTCTGTCTCAACCAAGAAATGCAGAGTGCCTTCACCACTCTGTAACCT,dna,PKLR promoter,GCF_000001405.26,,Regulatory +140,urn:mavedb:00000002-a-2,GACGTTCCACTGCCGGCTGGTTGGGAAATGGCTAAAACTAGTTCTGGTCAGCGTTACTTCCTGAACCACATCGACCAGACCACCACGTGGCAGGACCCGCGT,dna,hYAP65 WW domain,GCF_000001405.26,P46937,Protein coding +141,urn:mavedb:00000061-c-1,TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAAGAACAGTGGTCAATGTGCGAAATGGAATGAGCTTGCATGACTGCCTTATGAAAGCACTCAAGGTGAGGGGC,dna,RAF,GCF_000001405.26,P04049,Protein coding +142,urn:mavedb:00000035-a-2,ATGTTGTCAAGACTTTTTCGAATGCATGGCCTCTTTGTGGCCTCCCATCCCTGGGAAGTCATAGTGGGGACAGTGACACTGACCATCTGCATGATGTCCATGAACATGTTTACTGGTAACAATAAGATCTGTGGTTGGAATTATGAATGTCCAAAGTTTGAAGAGGATGTTTTGAGCAGTGACATTATAATTCTGACAATAACACGATGCATAGCCATCCTGTATATTTACTTCCAGTTCCAGAATTTACGTCAACTTGGATCAAAATATATTTTGGGTATTGCTGGCCTTTTCACAATTTTCTCAAGTTTTGTATTCAGTACAGTTGTCATTCACTTCTTAGACAAAGAATTGACAGGCTTGAATGAAGCTTTGCCCTTTTTCCTACTTTTGATTGACCTTTCCAGAGCAAGCACATTAGCAAAGTTTGCCCTCAGTTCCAACTCACAGGATGAAGTAAGGGAAAATATTGCTCGTGGAATGGCAATTTTAGGTCCTACGTTTACCCTCGATGCTCTTGTTGAATGTCTTGTGATTGGAGTTGGTACCATGTCAGGGGTACGTCAGCTTGAAATTATGTGCTGCTTTGGCTGCATGTCAGTTCTTGCCAACTACTTCGTGTTCATGACTTTCTTCCCAGCTTGTGTGTCCTTGGTATTAGAGCTTTCTCGGGAAAGCCGCGAGGGTCGTCCAATTTGGCAGCTCAGCCATTTTGCCCGAGTTTTAGAAGAAGAAGAAAATAAGCCGAATCCTGTAACTCAGAGGGTCAAGATGATTATGTCTCTAGGCTTGGTTCTTGTTCATGCTCACAGTCGCTGGATAGCTGATCCTTCTCCTCAAAACAGTACAGCAGATACTTCTAAGGTTTCATTAGGACTGGATGAAAATGTGTCCAAGAGAATTGAACCAAGTGTTTCCCTCTGGCAGTTTTATCTCTCTAAAATGATCAGCATGGATATTGAACAAGTTATTACCCTAAGTTTAGCTCTCCTTCTGGCTGTCAAGTACATCTTCTTTGAACAAACAGAGACAGAATCTACACTCTCATTAAAAAACCCTATCACATCTCCTGTAGTGACACAAAAGAAAGTCCCAGACAATTGTTGTAGACGTGAACCTATGCTGGTCAGAAATAACCAGAAATGTGATTCAGTAGAGGAAGAGACAGGGATAAACCGAGAAAGAAAAGTTGAGGTTATAAAACCCTTAGTGGCTGAAACAGATACCCCAAACAGAGCTACATTTGTGGTTGGTAACTCCTCCTTACTCGATACTTCATCAGTACTGGTGACACAGGAACCTGAAATTGAACTTCCCAGGGAACCTCGGCCTAATGAAGAATGTCTACAGATACTTGGGAATGCAGAGAAAGGTGCAAAATTCCTTAGTGATGCTGAGATCATCCAGTTAGTCAATGCTAAGCATATCCCAGCCTACAAGTTGGAAACTCTGATGGAAACTCATGAGCGTGGTGTATCTATTCGCCGACAGTTACTTTCCAAGAAGCTTTCAGAACCTTCTTCTCTCCAGTACCTACCTTACAGGGATTATAATTACTCCTTGGTGATGGGAGCTTGTTGTGAGAATGTTATTGGATATATGCCCATCCCTGTTGGAGTGGCAGGACCCCTTTGCTTAGATGAAAAAGAATTTCAGGTTCCAATGGCAACAACAGAAGGTTGTCTTGTGGCCAGCACCAATAGAGGCTGCAGAGCAATAGGTCTTGGTGGAGGTGCCAGCAGCCGAGTCCTTGCAGATGGGATGACTCGTGGCCCAGTTGTGCGTCTTCCACGTGCTTGTGACTCTGCAGAAGTGAAAGCCTGGCTCGAAACATCTGAAGGGTTCGCAGTGATAAAGGAGGCATTTGACAGCACTAGCAGATTTGCACGTCTACAGAAACTTCATACAAGTATAGCTGGACGCAACCTTTATATCCGTTTCCAGTCCAGGTCAGGGGATGCCATGGGGATGAACATGATTTCAAAGGGTACAGAGAAAGCACTTTCAAAACTTCACGAGTATTTCCCTGAAATGCAGATTCTAGCCGTTAGTGGTAACTATTGTACTGACAAGAAACCTGCTGCTATAAATTGGATAGAGGGAAGAGGAAAATCTGTTGTTTGTGAAGCTGTCATTCCAGCCAAGGTTGTCAGAGAAGTATTAAAGACTACCACAGAGGCTATGATTGAGGTCAACATTAACAAGAATTTAGTGGGCTCTGCCATGGCTGGGAGCATAGGAGGCTACAACGCCCATGCAGCAAACATTGTCACCGCCATCTACATTGCCTGTGGACAGGATGCAGCACAGAATGTTGGTAGTTCAAACTGTATTACTTTAATGGAAGCAAGTGGTCCCACAAATGAAGATTTATATATCAGCTGCACCATGCCATCTATAGAGATAGGAACGGTGGGTGGTGGGACCAACCTACTACCTCAGCAAGCCTGTTTGCAGATGCTAGGTGTTCAAGGAGCATGCAAAGATAATCCTGGGGAAAATGCCCGGCAGCTTGCCCGAATTGTGTGTGGGACCGTAATGGCTGGGGAATTGTCACTTATGGCAGCATTGGCAGCAGGACATCTTGTCAAAAGTCACATGATTCACAACAGGTCGAAGATCAATTTACAAGACCTCCAAGGAGCTTGCACCAAGAAGACAGCCTGA,dna,HMGCR,GCF_000001405.26,,Protein coding +143,urn:mavedb:00000031-b-1,TCGCGGGGGTGGCCGGGGCCAGGGCTTCCCACGTGCGCAGCAGGACGCAGCGCTGCCTGAAACTCGCGCCGCGAGGAGAGGGCGGGGCCGCGGAAAGGAAGGGGAGGGGCTGGGAGGGCCCGGAGGGGGCTGGGCCGGGGACCCGGGAGGGGTCGGGACGGGGCGGGGTCCGCGCGGAGGAGGCGGAGCTGGAAGGTGAAGGGGCAGGACGGGTGCCCGGGTCCCCAGTCCCTCCGCCACGTGGGAAGCGCGGTCCTGG,dna,TERT promoter,GCF_000001405.26,,Regulatory +144,urn:mavedb:00000035-a-3,ATGTTGTCAAGACTTTTTCGAATGCATGGCCTCTTTGTGGCCTCCCATCCCTGGGAAGTCATAGTGGGGACAGTGACACTGACCATCTGCATGATGTCCATGAACATGTTTACTGGTAACAATAAGATCTGTGGTTGGAATTATGAATGTCCAAAGTTTGAAGAGGATGTTTTGAGCAGTGACATTATAATTCTGACAATAACACGATGCATAGCCATCCTGTATATTTACTTCCAGTTCCAGAATTTACGTCAACTTGGATCAAAATATATTTTGGGTATTGCTGGCCTTTTCACAATTTTCTCAAGTTTTGTATTCAGTACAGTTGTCATTCACTTCTTAGACAAAGAATTGACAGGCTTGAATGAAGCTTTGCCCTTTTTCCTACTTTTGATTGACCTTTCCAGAGCAAGCACATTAGCAAAGTTTGCCCTCAGTTCCAACTCACAGGATGAAGTAAGGGAAAATATTGCTCGTGGAATGGCAATTTTAGGTCCTACGTTTACCCTCGATGCTCTTGTTGAATGTCTTGTGATTGGAGTTGGTACCATGTCAGGGGTACGTCAGCTTGAAATTATGTGCTGCTTTGGCTGCATGTCAGTTCTTGCCAACTACTTCGTGTTCATGACTTTCTTCCCAGCTTGTGTGTCCTTGGTATTAGAGCTTTCTCGGGAAAGCCGCGAGGGTCGTCCAATTTGGCAGCTCAGCCATTTTGCCCGAGTTTTAGAAGAAGAAGAAAATAAGCCGAATCCTGTAACTCAGAGGGTCAAGATGATTATGTCTCTAGGCTTGGTTCTTGTTCATGCTCACAGTCGCTGGATAGCTGATCCTTCTCCTCAAAACAGTACAGCAGATACTTCTAAGGTTTCATTAGGACTGGATGAAAATGTGTCCAAGAGAATTGAACCAAGTGTTTCCCTCTGGCAGTTTTATCTCTCTAAAATGATCAGCATGGATATTGAACAAGTTATTACCCTAAGTTTAGCTCTCCTTCTGGCTGTCAAGTACATCTTCTTTGAACAAACAGAGACAGAATCTACACTCTCATTAAAAAACCCTATCACATCTCCTGTAGTGACACAAAAGAAAGTCCCAGACAATTGTTGTAGACGTGAACCTATGCTGGTCAGAAATAACCAGAAATGTGATTCAGTAGAGGAAGAGACAGGGATAAACCGAGAAAGAAAAGTTGAGGTTATAAAACCCTTAGTGGCTGAAACAGATACCCCAAACAGAGCTACATTTGTGGTTGGTAACTCCTCCTTACTCGATACTTCATCAGTACTGGTGACACAGGAACCTGAAATTGAACTTCCCAGGGAACCTCGGCCTAATGAAGAATGTCTACAGATACTTGGGAATGCAGAGAAAGGTGCAAAATTCCTTAGTGATGCTGAGATCATCCAGTTAGTCAATGCTAAGCATATCCCAGCCTACAAGTTGGAAACTCTGATGGAAACTCATGAGCGTGGTGTATCTATTCGCCGACAGTTACTTTCCAAGAAGCTTTCAGAACCTTCTTCTCTCCAGTACCTACCTTACAGGGATTATAATTACTCCTTGGTGATGGGAGCTTGTTGTGAGAATGTTATTGGATATATGCCCATCCCTGTTGGAGTGGCAGGACCCCTTTGCTTAGATGAAAAAGAATTTCAGGTTCCAATGGCAACAACAGAAGGTTGTCTTGTGGCCAGCACCAATAGAGGCTGCAGAGCAATAGGTCTTGGTGGAGGTGCCAGCAGCCGAGTCCTTGCAGATGGGATGACTCGTGGCCCAGTTGTGCGTCTTCCACGTGCTTGTGACTCTGCAGAAGTGAAAGCCTGGCTCGAAACATCTGAAGGGTTCGCAGTGATAAAGGAGGCATTTGACAGCACTAGCAGATTTGCACGTCTACAGAAACTTCATACAAGTATAGCTGGACGCAACCTTTATATCCGTTTCCAGTCCAGGTCAGGGGATGCCATGGGGATGAACATGATTTCAAAGGGTACAGAGAAAGCACTTTCAAAACTTCACGAGTATTTCCCTGAAATGCAGATTCTAGCCGTTAGTGGTAACTATTGTACTGACAAGAAACCTGCTGCTATAAATTGGATAGAGGGAAGAGGAAAATCTGTTGTTTGTGAAGCTGTCATTCCAGCCAAGGTTGTCAGAGAAGTATTAAAGACTACCACAGAGGCTATGATTGAGGTCAACATTAACAAGAATTTAGTGGGCTCTGCCATGGCTGGGAGCATAGGAGGCTACAACGCCCATGCAGCAAACATTGTCACCGCCATCTACATTGCCTGTGGACAGGATGCAGCACAGAATGTTGGTAGTTCAAACTGTATTACTTTAATGGAAGCAAGTGGTCCCACAAATGAAGATTTATATATCAGCTGCACCATGCCATCTATAGAGATAGGAACGGTGGGTGGTGGGACCAACCTACTACCTCAGCAAGCCTGTTTGCAGATGCTAGGTGTTCAAGGAGCATGCAAAGATAATCCTGGGGAAAATGCCCGGCAGCTTGCCCGAATTGTGTGTGGGACCGTAATGGCTGGGGAATTGTCACTTATGGCAGCATTGGCAGCAGGACATCTTGTCAAAAGTCACATGATTCACAACAGGTCGAAGATCAATTTACAAGACCTCCAAGGAGCTTGCACCAAGAAGACAGCCTGA,dna,HMGCR,GCF_000001405.26,,Protein coding +145,urn:mavedb:00000006-a-1,TCTTCAATCTGGGTATGCTGACTCAACCAGAATAACAGTGAAAATGATAATTCAAACTAATACTGTTTACAGGGAGTTAAACTTCTACAGTGGGATTAAAGGTCTGTACCACGTTAGCACAAATGTCACCTCTCTGTTAATCATAAAACAGGGTCACAGGCCAATGTTCACCACAAGGAGACAGGAGGACAACCTGGGATGGGTAATGACAAAGAACGATTTCCGTACTCCTAAGCCTCTGCTCTCTCAGATCTCAAGC,dna,ALDOB enhancer,GCF_000001405.13,,Regulatory +146,urn:mavedb:00000094-a-13,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +147,urn:mavedb:00000045-h-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +148,urn:mavedb:00000051-c-1,CTCATTATTTTTGGGGTGATGGCTGGTGTTATTGGAACGATCCTG,dna,Glycophorin A,GCF_000001405.26,P02724,Protein coding +149,urn:mavedb:00000097-u-1,ATGTCCATTTTAGATCAACTGGAATGGATGGTACAGCTGTGTGGTGCTTCTGTGGTGAAGGAGCTTTCATCATTCACCCTTGGCACAGTAAGTATTGGGTGCCCT,dna,BRCA1 Exon 21,GCF_000001405.13,,Protein coding +150,urn:mavedb:00000097-d-1,TTTCTCCCCCCCTACCCTGCTAGTCTGGAGTTGATCAAGGAACCTGTCTCCACAAAGTGTGACCACATATTTTGCAAGTAAGTTTGAATGTGTTATGTGG,dna,BRCA1 Exon 3,GCF_000001405.13,,Protein coding +151,urn:mavedb:00000036-a-1,ATGGACGCGCTCAAGTCGGCGGGGCGGGCGCTGATCCGGAGCCCCAGCTTGGCCAAGCAGAGCTGGGGGGGCGGTGGCCGGCACCGCAAGCTGCCTGAGAACTGGACAGACACGCGGGAGACGCTGCTGGAGGGGATGCTGTTCAGCCTCAAGTACCTGGGCATGACGCTAGTGGAGCAGCCCAAGGGTGAGGAGCTGTCGGCCGCCGCCATCAAGAGGATCGTGGCTACAGCTAAGGCCAGTGGGAAGAAGCTGCAGAAGGTGACTCTGAAGGTGTCGCCACGGGGAATTATCCTGACAGACAACCTCACCAACCAGCTCATTGAGAACGTGTCCATATACAGGATCTCCTATTGCACAGCAGACAAGATGCACGACAAGGTGTTTGCATACATCGCCCAGAGCCAGCACAACCAGAGCCTCGAGTGCCACGCCTTCCTCTGCACCAAGCGGAAGATGGCACAGGCTGTTACCCTCACCGTAGCCCAGGCCTTCAAAGTCGCCTTTGAGTTTTGGCAGGTGTCCAAGGAAGAGAAAGAGAAGAGGGACAAAGCCAGCCAAGAGGGAGGGGACGTCCTGGGGGCCCGCCAAGACTGCACCCCCCCCTTGAAGAGCTTGGTCGCCACTGGGAACCTGCTGGACTTAGAGGAGACGGCTAAGGCCCCGCTGTCCACGGTCAGCGCCAACACCACCAACATGGACGAGGTGCCGCGGCCACAAGCCTTGAGTGGCAGCAGTGTTGTCTGGGAGCTGGATGATGGCCTGGATGAAGCGTTTTCGAGGCTTGCCCAGTCTCGGACAAACCCTCAGGTCCTGGACACTGGCCTGACAGCCCAGGACATGCATTACGCCCAGTGCCTCTCGCCTGTCGACTGGGACAAGCCTGACAGCAGCGGCACAGAGCAGGATGACCTCTTCAGCTTCTGA,dna,LDLRAP1,GCF_000001405.26,,Protein coding +152,urn:mavedb:00000105-a-1,QYKLILNGKTLKGETTTEAVDAATAEKVFKQYANDNGVDGEWTYDDATKTFTVTEKPEVIDASELTPAVTTYKLVINGKTLKGETTTKAVDAETAEKAFKQYANDNGVDGVWTYDDATKTFTVTEMVTEVPGDAPTEPEKPEASIPLVPLTPATPIAKDDAKKDDTKKEDAKKPEAKKDDAKKAETLPTTGEGSNPFFTAAALAVMAGAGALAVASKRKED,protein,GB1,GCF_000001405.26,,Protein coding +153,urn:mavedb:00000081-a-2,MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKEFVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHSRETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVTFECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRGNETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY,protein,BRCA1,GCF_000001405.13,,Protein coding +154,urn:mavedb:00000053-a-2,CCACGCCGCATCGTCATCCACCGTGGGTCAACGGGGTTAGGCTTCAATATCGTCGGTGGAGAGGATGGTGAGGGAATCTTCATCTCATTCATTCTGGCGGGAGGACCGGCCGATTTAAGCGGAGAACTTCGCAAAGGTGACCAGATCCTTTCGGTGAATGGCGTAGATTTGCGCAACGCATCACACGAACAGGCGGCCATCGCATTAAAGAACGCCGGCCAGACCGTTACGATTATCGCGCAGTATAAA,dna,PSD95 PDZ3,GCF_000001405.26,P78352,Protein coding +155,urn:mavedb:00000060-a-1,ATGTCTGAATATATTCGGGTAACCGAAGATGAGAACGATGAGCCCATTGAAATACCATCGGAAGACGATGGGACGGTGCTGCTCTCCACGGTTACAGCCCAGTTTCCAGGGGCGTGTGGGCTTCGCTACAGGAATCCAGTGTCTCAGTGTATGAGAGGTGTCCGGCTGGTAGAAGGAATTCTGCATGCCCCAGATGCTGGCTGGGGAAATCTGGTGTATGTTGTCAACTATCCAAAAGATAACAAAAGAAAAATGGATGAGACAGATGCTTCATCAGCAGTGAAAGTGAAAAGAGCAGTCCAGAAAACATCCGATTTAATAGTGTTGGGTCTCCCATGGAAAACAACCGAACAGGACCTGAAAGAGTATTTTAGTACCTTTGGAGAAGTTCTTATGGTGCAGGTCAAGAAAGATCTTAAGACTGGTCATTCAAAGGGGTTTGGCTTTGTTCGTTTTACGGAATATGAAACACAAGTGAAAGTAATGTCACAGCGACATATGATAGATGGACGATGGTGTGACTGCAAACTTCCTAATTCTAAGCAAAGCCAAGATGAGCCTTTGAGAAGCAGAAAAGTGTTTGTGGGGCGCTGTACAGAGGACATGACTGAGGATGAGCTGCGGGAGTTCTTCTCTCAGTACGGGGATGTGATGGATGTCTTCATCCCCAAGCCATTCAGGGCCTTTGCCTTTGTTACATTTGCAGATGATCAGATTGCGCAGTCTCTTTGTGGAGAGGACTTGATCATTAAAGGAATCAGCGTTCATATATCCAATGCCGAACCTAAGCACAATAGCAATAGACAGTTAGAAAGAAGTGGAAGATTTGGTGGTAATCCAGGTGGCTTTGGGAATCAGGGTGGATTTGGTAATAGCAGAGGGGGTGGAGCTGGTTTGGGAAACAATCAAGGTAGTAATATGGGTGGTGGGATGAACTTTGGTGCGTTCAGCATTAATCCAGCCATGATGGCTGCCGCCCAGGCAGCACTACAGAGCAGTTGGGGTATGATGGGCATGTTAGCCAGCCAGCAGAACCAGTCAGGCCCATCGGGTAATAACCAAAACCAAGGCAACATGCAGAGGGAGCCAAACCAGGCCTTCGGTTCTGGAAATAACTCTTATAGTGGCTCTAATTCTGGTGCAGCAATTGGTTGGGGATCAGCATCCAATGCAGGGTCGGGCAGTGGTTTTAATGGAGGCTTTGGCTCAAGCATGGATTCTAAGTCTTCTGGCTGGGGAATG,dna,TARDBP,GCF_000001405.13,Q13148,Protein coding +156,urn:mavedb:00000013-a-1,ATGACAGCCATCATCAAAGAGATCGTTAGCAGAAACAAAAGGAGATATCAAGAGGATGGATTCGACTTAGACTTGACCTATATTTATCCAAACATTATTGCTATGGGATTTCCTGCAGAAAGACTTGAAGGCGTATACAGGAACAATATTGATGATGTAGTAAGGTTTTTGGATTCAAAGCATAAAAACCATTACAAGATATACAATCTTTGTGCTGAAAGACATTATGACACCGCCAAATTTAATTGCAGAGTTGCACAATATCCTTTTGAAGACCATAACCCACCACAGCTAGAACTTATCAAACCCTTTTGTGAAGATCTTGACCAATGGCTAAGTGAAGATGACAATCATGTTGCAGCAATTCACTGTAAAGCTGGAAAGGGACGAACTGGTGTAATGATATGTGCATATTTATTACATCGGGGCAAATTTTTAAAGGCACAAGAGGCCCTAGATTTCTATGGGGAAGTAAGGACCAGAGACAAAAAGGGAGTAACTATTCCCAGTCAGAGGCGCTATGTGTATTATTATAGCTACCTGTTAAAGAATCATCTGGATTATAGACCAGTGGCACTGTTGTTTCACAAGATGATGTTTGAAACTATTCCAATGTTCAGTGGCGGAACTTGCAATCCTCAGTTTGTGGTCTGCCAGCTAAAGGTGAAGATATATTCCTCCAATTCAGGACCCACACGACGGGAAGACAAGTTCATGTACTTTGAGTTCCCTCAGCCGTTACCTGTGTGTGGTGATATCAAAGTAGAGTTCTTCCACAAACAGAACAAGATGCTAAAAAAGGACAAAATGTTTCACTTTTGGGTAAATACATTCTTCATACCAGGACCAGAGGAAACCTCAGAAAAAGTAGAAAATGGAAGTCTATGTGATCAAGAAATCGATAGCATTTGCAGTATAGAGCGTGCAGATAATGACAAGGAATATCTAGTACTTACTTTAACAAAAAATGATCTTGACAAAGCAAATAAAGACAAAGCCAACCGATACTTTTCTCCAAATTTTAAGGTGAAGCTGTACTTCACAAAAACAGTAGAGGAGCCGTCAAATCCAGAGGCTAGCAGTTCAACTTCTGTAACACCAGATGTTAGTGACAATGAACCTGATCATTATAGATATTCTGACACCACTGACTCTGATCCAGAGAATGAACCTTTTGATGAAGATCAGCATACACAAATTACAAAAGTCTGA,dna,PTEN,GCF_000001405.26,P60484,Protein coding +157,urn:mavedb:00000022-a-1,GTAAATGGTGAGTAGGAAGTTGATTCTGCCCGATCTGTCTGACTCCATGCCCTTTCTATTAGGTCATGAAGGGGAACCTGAGGATTGGAGCTTTGGAATGTTAATCTTACCCAAAGGCCTGAAGTAATACCCCAGAATGTGAACATGTGTGACCATCTGCCTGTCCTGGGGGTGGGAAGAAGGCAGCATGCTCTATCCTTGACCCTGATTGAGCCCAGGGGCTGAATCTGGAGCTTTGGGGCCTGGGAACCTCTCTACCTGCGTCAATGTCTGGAGGCCCTGAGAGTTTCGCTCAGGCTCAGAGCAGGCATCGCAACCTCCCAGTTACTATTCTGTGCTGTGGCAAGTGCCAGCTTGTCCTCTCTTCCCCACCCAGCCCGGGAAACCGGCAGCATTTCTAGTTCAGGCCCAGACCCGTCCTGGCAGCCTGGATTCCACTGCCTAGGCAGGAAGCTCATCTCAGCCCAGTGACCTTTTCTCTCTGTTTTTTGTCACAGAGGAATTTCCATGCCAGCAGTATGGGGCAATGGGGGTGGGTGGCCAAAGGTTTCCCCCTTAAGCCACAAGAGCCATGGAGTGGAGGTAAGCTAAGCAAACAGAG,dna,IRF6 enhancer,GCF_000001405.26,,Regulatory +158,urn:mavedb:00000097-z-1,CTGTCTCCAGCAATTGGGCAGATGTGTGAGGCACCTGTGGTGACCCGAGAGTGGGTGTTGGACAGTGTAGCACTCTACCAGTGCCAGGAGCTGGACACCTACCTGATA,dna,BRCA1 Exon 23,GCF_000001405.13,,Protein coding +159,urn:mavedb:00000094-a-9,MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD,protein,KCNQ4,GCF_000001405.26,,Protein coding +160,urn:mavedb:00000045-e-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +161,urn:mavedb:00000097-j-1,AGTGTGAGCAGGGAGAAGCCAGAATTGACAGCTTCAACAGAAAGGGTCAACAAAAGAATGTCCATGGTGGTGTCTGGCCTGACCCCAGAAGAATTTGTGAGTGTAT,dna,BRCA1 Exon 15,GCF_000001405.13,,Protein coding +162,urn:mavedb:00000047-b-1,GATTATCAAGTGTCAAGTCCAATCTATGACATCAATTATTATACATCGGAGCCCTGCCAAAAAATCAATGTGAAGCAAATCGCAGCCCGCCTCCTGCCTCCGCTCTACTCACTGGTGTTCATCTTTGGTTTTGTGGGCAACATGCTGGTCATCCTCATCCTGATAAACTGCAAAAGGCTGAAGAGCATGACTGACATCTACCTGCTCAACCTGGCCATCTCTGACCTGTTTTTCCTTCTTACTGTCCCCTTCTGGGCTCACTATGCTGCCGCCCAGTGGGACTTTGGAAATACAATGTGTCAACTCTTGACAGGGCTCTATTTTATAGGCTTCTTCTCTGGAATCTTCTTCATCATCCTCCTGACAATCGATAGGTACCTGGCTGTCGTCCATGCTGTGTTTGCTTTAAAAGCCAGGACGGTCACCTTTGGGGTGGTGACAAGTGTGATCACTTGGGTGGTGGCTGTGTTTGCGTCTCTCCCAGGAATCATCTTTACCAGATCTCAAAAAGAAGGTCTTCATTACACCTGCAGCTCTCATTTTCCATACAGTCAGTATCAATTCTGGAAGAATTTCCAGACATTAAAGATAGTCATCTTGGGGCTGGTCCTGCCGCTGCTTGTCATGGTCATCTGCTACTCGGGAATCCTAAAAACTCTGCTTCGGTGTCGAAATGAGAAGAAGAGGCACAGGGCTGTGAGGCTTATCTTCACCATCATGATTGTTTATTTTCTCTTCTGGGCTCCCTACAACATTGTCCTTCTCCTGAACACCTTCCAGGAATTCTTTGGCCTGAATAATTGCAGTAGCTCTAACAGGTTGGACCAAGCTATGCAGGTGACAGAGACTCTTGGGATGACGCACTGCTGCATCAACCCCATCATCTATGCCTTTGTCGGGGAGAAGTTCAGAAACTACCTCTTAGTCTTCTTCCAAAAGCACATTGCCAAACGCTTCTGCAAATGCTGTTCTATTTTCCAGCAAGAGGCTCCCGAGCGAGCAAGCTCAGTTTACACCCGATCCACTGGGGAGCAGGAAATATCTGTGGGCTTG,dna,CCR5,GCF_000001405.26,P51681,Protein coding +163,urn:mavedb:00000003-b-1,GATTTATCTGCTCTTCGCGTTGAAGAAGTACAAAATGTCATTAATGCTATGCAGAAAATCTTAGAGTGTCCCATCTGCCTGGAGTTGATCAAGGAACCTGTCTCCACAAAGTGTGACCACATATTTTGCAAATTTTGCATGCTGAAACTTCTCAACCAGAAGAAAGGGCCTTCACAGTGTCCTTTATGTAAGAATGATATAACCAAAAGGAGCCTACAAGAAAGTACGAGATTTAGTCAACTTGTTGAAGAGCTATTGAAAATCATTTGTGCTTTTCAGCTTGACACAGGTTTGGAGTATGCAAACAGCTATAATTTTGCAAAAAAGGAAAATAACTCTCCTGAACATCTAAAAGATGAAGTTTCTATCATCCAAAGTATGGGCTACAGAAACCGTGCCAAAAGACTTCTACAGAGTGAACCCGAAAATCCTTCCTTGCAGGAAACCAGTCTCAGTGTCCAACTCTCTAACCTTGGAACTGTGAGAACTCTGAGGACAAAGCAGCGGATACAACCTCAAAGGACGTCTGTCTACATTGAATTGGGATCTGATTCTTCTGAAGATACCGTTAATAAGGCAACTTATTGCAGTGTGGGAGATCAAGAATTGTTACAAATCACCCCTCAAGGAACCAGGGATGAAATCAGTTTGGATTCTGCAAAAAAGGCTGCTTGTGAATTTTCTGAGACGGATGTAACAAATACTGAACATCATCAACCCAGTAATAATGATTTGAACACCACTGAGAAGCGTGCAGCTGAGAGGCATCCAGAAAAGTATCAGGGTAGTTCTGTTTCAAACTTGCATGTGGAGCCATGTGGCACAAATACTCATGCCAGCTCATTACAGCATGAGAACAGCAGTTTATTACTCACTAAAGACAGAATGAATGTAGAAAAGGCTGAGTTC,dna,BRCA1 RING domain,GCF_000001405.26,,Protein coding +164,urn:mavedb:00000054-a-1,ATGACAGCCATCATCAAAGAGATCGTTAGCAGAAACAAAAGGAGATATCAAGAGGATGGATTCGACTTAGACTTGACCTATATTTATCCAAACATTATTGCTATGGGATTTCCTGCAGAAAGACTTGAAGGCGTATACAGGAACAATATTGATGATGTAGTAAGGTTTTTGGATTCAAAGCATAAAAACCATTACAAGATATACAATCTTTGTGCTGAAAGACATTATGACACCGCCAAATTTAATTGCAGAGTTGCACAATATCCTTTTGAAGACCATAACCCACCACAGCTAGAACTTATCAAACCCTTTTGTGAAGATCTTGACCAATGGCTAAGTGAAGATGACAATCATGTTGCAGCAATTCACTGTAAAGCTGGAAAGGGACGAACTGGTGTAATGATATGTGCATATTTATTACATCGGGGCAAATTTTTAAAGGCACAAGAGGCCCTAGATTTCTATGGGGAAGTAAGGACCAGAGACAAAAAGGGAGTAACTATTCCCAGTCAGAGGCGCTATGTGTATTATTATAGCTACCTGTTAAAGAATCATCTGGATTATAGACCAGTGGCACTGTTGTTTCACAAGATGATGTTTGAAACTATTCCAATGTTCAGTGGCGGAACTTGCAATCCTCAGTTTGTGGTCTGCCAGCTAAAGGTGAAGATATATTCCTCCAATTCAGGACCCACACGACGGGAAGACAAGTTCATGTACTTTGAGTTCCCTCAGCCGTTACCTGTGTGTGGTGATATCAAAGTAGAGTTCTTCCACAAACAGAACAAGATGCTAAAAAAGGACAAAATGTTTCACTTTTGGGTAAATACATTCTTCATACCAGGACCAGAGGAAACCTCAGAAAAAGTAGAAAATGGAAGTCTATGTGATCAAGAAATCGATAGCATTTGCAGTATAGAGCGTGCAGATAATGACAAGGAATATCTAGTACTTACTTTAACAAAAAATGATCTTGACAAAGCAAATAAAGACAAAGCCAACCGATACTTTTCTCCAAATTTTAAGGTGAAGCTGTACTTCACAAAAACAGTAGAGGAGCCGTCAAATCCAGAGGCTAGCAGTTCAACTTCTGTAACACCAGATGTTAGTGACAATGAACCTGATCATTATAGATATTCTGACACCACTGACTCTGATCCAGAGAATGAACCTTTTGATGAAGATCAGCATACACAAATTACAAAAGTCTGA,dna,PTEN,GCF_000001405.26,P60484,Protein coding +165,urn:mavedb:00000061-a-1,TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAAGAACAGTGGTCAATGTGCGAAATGGAATGAGCTTGCATGACTGCCTTATGAAAGCACTCAAGGTGAGGGGC,dna,RAF,GCF_000001405.26,P04049,Protein coding +166,urn:mavedb:00000047-a-1,GATTATCAAGTGTCAAGTCCAATCTATGACATCAATTATTATACATCGGAGCCCTGCCAAAAAATCAATGTGAAGCAAATCGCAGCCCGCCTCCTGCCTCCGCTCTACTCACTGGTGTTCATCTTTGGTTTTGTGGGCAACATGCTGGTCATCCTCATCCTGATAAACTGCAAAAGGCTGAAGAGCATGACTGACATCTACCTGCTCAACCTGGCCATCTCTGACCTGTTTTTCCTTCTTACTGTCCCCTTCTGGGCTCACTATGCTGCCGCCCAGTGGGACTTTGGAAATACAATGTGTCAACTCTTGACAGGGCTCTATTTTATAGGCTTCTTCTCTGGAATCTTCTTCATCATCCTCCTGACAATCGATAGGTACCTGGCTGTCGTCCATGCTGTGTTTGCTTTAAAAGCCAGGACGGTCACCTTTGGGGTGGTGACAAGTGTGATCACTTGGGTGGTGGCTGTGTTTGCGTCTCTCCCAGGAATCATCTTTACCAGATCTCAAAAAGAAGGTCTTCATTACACCTGCAGCTCTCATTTTCCATACAGTCAGTATCAATTCTGGAAGAATTTCCAGACATTAAAGATAGTCATCTTGGGGCTGGTCCTGCCGCTGCTTGTCATGGTCATCTGCTACTCGGGAATCCTAAAAACTCTGCTTCGGTGTCGAAATGAGAAGAAGAGGCACAGGGCTGTGAGGCTTATCTTCACCATCATGATTGTTTATTTTCTCTTCTGGGCTCCCTACAACATTGTCCTTCTCCTGAACACCTTCCAGGAATTCTTTGGCCTGAATAATTGCAGTAGCTCTAACAGGTTGGACCAAGCTATGCAGGTGACAGAGACTCTTGGGATGACGCACTGCTGCATCAACCCCATCATCTATGCCTTTGTCGGGGAGAAGTTCAGAAACTACCTCTTAGTCTTCTTCCAAAAGCACATTGCCAAACGCTTCTGCAAATGCTGTTCTATTTTCCAGCAAGAGGCTCCCGAGCGAGCAAGCTCAGTTTACACCCGATCCACTGGGGAGCAGGAAATATCTGTGGGCTTG,dna,CCR5,GCF_000001405.26,P51681,Protein coding +167,urn:mavedb:00000035-a-1,ATGTTGTCAAGACTTTTTCGAATGCATGGCCTCTTTGTGGCCTCCCATCCCTGGGAAGTCATAGTGGGGACAGTGACACTGACCATCTGCATGATGTCCATGAACATGTTTACTGGTAACAATAAGATCTGTGGTTGGAATTATGAATGTCCAAAGTTTGAAGAGGATGTTTTGAGCAGTGACATTATAATTCTGACAATAACACGATGCATAGCCATCCTGTATATTTACTTCCAGTTCCAGAATTTACGTCAACTTGGATCAAAATATATTTTGGGTATTGCTGGCCTTTTCACAATTTTCTCAAGTTTTGTATTCAGTACAGTTGTCATTCACTTCTTAGACAAAGAATTGACAGGCTTGAATGAAGCTTTGCCCTTTTTCCTACTTTTGATTGACCTTTCCAGAGCAAGCACATTAGCAAAGTTTGCCCTCAGTTCCAACTCACAGGATGAAGTAAGGGAAAATATTGCTCGTGGAATGGCAATTTTAGGTCCTACGTTTACCCTCGATGCTCTTGTTGAATGTCTTGTGATTGGAGTTGGTACCATGTCAGGGGTACGTCAGCTTGAAATTATGTGCTGCTTTGGCTGCATGTCAGTTCTTGCCAACTACTTCGTGTTCATGACTTTCTTCCCAGCTTGTGTGTCCTTGGTATTAGAGCTTTCTCGGGAAAGCCGCGAGGGTCGTCCAATTTGGCAGCTCAGCCATTTTGCCCGAGTTTTAGAAGAAGAAGAAAATAAGCCGAATCCTGTAACTCAGAGGGTCAAGATGATTATGTCTCTAGGCTTGGTTCTTGTTCATGCTCACAGTCGCTGGATAGCTGATCCTTCTCCTCAAAACAGTACAGCAGATACTTCTAAGGTTTCATTAGGACTGGATGAAAATGTGTCCAAGAGAATTGAACCAAGTGTTTCCCTCTGGCAGTTTTATCTCTCTAAAATGATCAGCATGGATATTGAACAAGTTATTACCCTAAGTTTAGCTCTCCTTCTGGCTGTCAAGTACATCTTCTTTGAACAAACAGAGACAGAATCTACACTCTCATTAAAAAACCCTATCACATCTCCTGTAGTGACACAAAAGAAAGTCCCAGACAATTGTTGTAGACGTGAACCTATGCTGGTCAGAAATAACCAGAAATGTGATTCAGTAGAGGAAGAGACAGGGATAAACCGAGAAAGAAAAGTTGAGGTTATAAAACCCTTAGTGGCTGAAACAGATACCCCAAACAGAGCTACATTTGTGGTTGGTAACTCCTCCTTACTCGATACTTCATCAGTACTGGTGACACAGGAACCTGAAATTGAACTTCCCAGGGAACCTCGGCCTAATGAAGAATGTCTACAGATACTTGGGAATGCAGAGAAAGGTGCAAAATTCCTTAGTGATGCTGAGATCATCCAGTTAGTCAATGCTAAGCATATCCCAGCCTACAAGTTGGAAACTCTGATGGAAACTCATGAGCGTGGTGTATCTATTCGCCGACAGTTACTTTCCAAGAAGCTTTCAGAACCTTCTTCTCTCCAGTACCTACCTTACAGGGATTATAATTACTCCTTGGTGATGGGAGCTTGTTGTGAGAATGTTATTGGATATATGCCCATCCCTGTTGGAGTGGCAGGACCCCTTTGCTTAGATGAAAAAGAATTTCAGGTTCCAATGGCAACAACAGAAGGTTGTCTTGTGGCCAGCACCAATAGAGGCTGCAGAGCAATAGGTCTTGGTGGAGGTGCCAGCAGCCGAGTCCTTGCAGATGGGATGACTCGTGGCCCAGTTGTGCGTCTTCCACGTGCTTGTGACTCTGCAGAAGTGAAAGCCTGGCTCGAAACATCTGAAGGGTTCGCAGTGATAAAGGAGGCATTTGACAGCACTAGCAGATTTGCACGTCTACAGAAACTTCATACAAGTATAGCTGGACGCAACCTTTATATCCGTTTCCAGTCCAGGTCAGGGGATGCCATGGGGATGAACATGATTTCAAAGGGTACAGAGAAAGCACTTTCAAAACTTCACGAGTATTTCCCTGAAATGCAGATTCTAGCCGTTAGTGGTAACTATTGTACTGACAAGAAACCTGCTGCTATAAATTGGATAGAGGGAAGAGGAAAATCTGTTGTTTGTGAAGCTGTCATTCCAGCCAAGGTTGTCAGAGAAGTATTAAAGACTACCACAGAGGCTATGATTGAGGTCAACATTAACAAGAATTTAGTGGGCTCTGCCATGGCTGGGAGCATAGGAGGCTACAACGCCCATGCAGCAAACATTGTCACCGCCATCTACATTGCCTGTGGACAGGATGCAGCACAGAATGTTGGTAGTTCAAACTGTATTACTTTAATGGAAGCAAGTGGTCCCACAAATGAAGATTTATATATCAGCTGCACCATGCCATCTATAGAGATAGGAACGGTGGGTGGTGGGACCAACCTACTACCTCAGCAAGCCTGTTTGCAGATGCTAGGTGTTCAAGGAGCATGCAAAGATAATCCTGGGGAAAATGCCCGGCAGCTTGCCCGAATTGTGTGTGGGACCGTAATGGCTGGGGAATTGTCACTTATGGCAGCATTGGCAGCAGGACATCTTGTCAAAAGTCACATGATTCACAACAGGTCGAAGATCAATTTACAAGACCTCCAAGGAGCTTGCACCAAGAAGACAGCCTGA,dna,HMGCR,GCF_000001405.26,,Protein coding +168,urn:mavedb:00000015-a-1,GTCCCACTGATGAACTGTGCTGCCACAGTAAATGTAGCCACTATGCCTATCTCCATTCTGAAGATGTGTCACTTCCTGTTTCAGACTCAAATCAGCCACAGTGGCAGAAGCCCACGAAATCAGAGGTGAAATTTAATAATGACCACTGCCCATTCTCTTCACTTGTCCCAAGAGGCCATTGGAAATAGTCCAAAGACCCATTGAGGGAGATGGACATTATTTCCCAGAAGTAAATACAGCTCAGCTTGTACTTTGGTACAACTAATCGACCTTACCACTTTCACAATCTGCTAGCAAAGGTTA,dna,F9 promoter,GCF_000001405.26,,Regulatory +169,urn:mavedb:00000078-b-1,MGSTWGSPGWVRLALCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWGRGFGLVEHVLGQDSILNQSNSIFGCIFYTLQLLLGCLRTRWASVLMLLSSLVSLAGSVYLAWILFFVLYDFCIVCITTYAINVSLMWLSFRKVQEPQGKAKRH,protein,VKOR,GCF_000001405.26,,Protein coding +170,urn:mavedb:00000025-a-1,CTGCATCGCTCCATAGAGCCTGCAGAGGGCACTAGACTGGGAATTAGAAAACCTGATTTCCCTTCCAGCTCCACCTCTGACCAATTGCCTGACCCTGGTCAAATTGCTTAACCTCTTCCTATCTCAGCTCCCTATCCATAAAACAGAGGGACGAATAAACTCTCCTCCTACCACTAAGAGGTGTAGCCAGAGTTAATACCCTCATCGTCCTTTGAGCTCAGCAGATGAAAGGCACTGAGAAAAGTACAAAGAATTTTTATGTGCTATTGACTTTATTTTATTTTATGTGGGGGAGGGAGCCGGCCCCAGCTGGAAAGCTGCTTTCTCTGAATCAAAGGGCAGGAACCCAGCAAGTTTCTCAGGATTGGGGCCTTAGACTGGGCTGTGTATACAGACAGTGCCAGCCAACCCCACAGTTCAGTTTCCTTTAACCTGGTGCTCCAGGCAATAACTGTGCAACTCTGCAATTTAACAATGTGTTCTTTGTCCCACAACTGTTCTCGTTTCTCAACTGCCCAGGTAATATGTTTGGGCCTGTAGGAAGAGTCAAATAGTTAATAAGGGAAGGGTTTGGCATGCCCTACGTAAGTTCTACCAGCA,dna,MYC enhancer (rs6983267),GCF_000001405.26,,Regulatory +171,urn:mavedb:00000045-l-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +172,urn:mavedb:00000065-a-1,ATGGGGAAATCCAACAGCAAGTTGAAGCCCGAAGTTGTGGAGGAGCTGACCAGGAAGACCTACTTTACCGAGAAGGAGGTCCAGCAGTGGTACAAAGGCTTCATCAAGGACTGCCCCAGTGGGCAGCTGGATGCGGCAGGCTTCCAGAAGATCTACAAGCAATTCTTCCCGTTCGGAGACCCCACCAAGTTTGCCACATTTGTTTTCAACGTCTTTGATGAAAACAAGGACGGGCGAATTGAGTTCTCCGAGTTCATCCAGGCGCTGTCGGTGACCTCACGGGGAACCCTGGATGAGAAGCTACGGTGGGCCTTCAAGCTCTACGACTTGGACAATGATGGCTACATCACCAGGAATGAGATGCTGGACATTGTGGATGCCATTTACCAGATGGTGGGGAATACCGTGGAGCTCCCAGAGGAGGAGAACACTCCTGAGAAGAGGGTGGACCGGATCTTTGCCATGATGGATAAGAATGCCGACGGGAAGCTGACCCTGCAGGAGTTCCAGGAGGGTTCCAAGGCAGACCCGTCCATTGTGCAGGCGCTGTCCCTCTACGACGGGCTGGTATAG,dna,NCS1,GCF_000001405.26,,Protein coding +173,urn:mavedb:00000046-a-3,GACCACATTCCTTGGATTACAGCTGTACTTCCAACAGTTATTATATGTGTGATGGTTTTCTGTCTAATTCTATGGAAATGG,dna,CD86,GCF_000001405.10,P42081,Protein coding +174,urn:mavedb:00000068-c-1,ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAACGTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCAGATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCGCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCCTGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAGTCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACACCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAGCGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAACACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGTTCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGTGGTAATCTACTGGGACGGAACAGCTTTGAGGTGCGTGTTTGTGCCTGTCCTGGGAGAGACCGGCGCACAGAGGAAGAGAATCTCCGCAAGAAAGGGGAGCCTCACCACGAGCTGCCCCCAGGGAGCACTAAGCGAGCACTGCCCAACAACACCAGCTCCTCTCCCCAGCCAAAGAAGAAACCACTGGATGGAGAATATTTCACCCTTCAGATCCGTGGGCGTGAGCGCTTCGAGATGTTCCGAGAGCTGAATGAGGCCTTGGAACTCAAGGATGCCCAGGCTGGGAAGGAGCCAGGGGGGAGCAGGGCTCACTCCAGCCACCTGAAGTCCAAAAAGGGTCAGTCTACCTCCCGCCATAAAAAACTCATGTTCAAGACAGAAGGGCCTGACTCAGACTAG,dna,TP53 (P72R),GCF_000001405.26,,Protein coding +175,urn:mavedb:00000005-a-2,ATGCCTTCTGAGACCCCCCAGGCAGAAGTGGGGCCCACAGGCTGCCCCCACCGCTCAGGGCCACACTCGGCGAAGGGGAGCCTGGAGAAGGGGTCCCCAGAGGATAAGGAAGCCAAGGAGCCCCTGTGGATCCGGCCCGATGCTCCGAGCAGGTGCACCTGGCAGCTGGGCCGGCCTGCCTCCGAGTCCCCACATCACCACACTGCCCCGGCAAAATCTCCAAAAATCTTGCCAGATATTCTGAAGAAAATCGGGGACACCCCTATGGTCAGAATCAACAAGATTGGGAAGAAGTTCGGCCTGAAGTGTGAGCTCTTGGCCAAGTGTGAGTTCTTCAACGCGGGCGGGAGCGTGAAGGACCGCATCAGCCTGCGGATGATTGAGGATGCTGAGCGCGACGGGACGCTGAAGCCCGGGGACACGATTATCGAGCCGACATCCGGGAACACCGGGATCGGGCTGGCCCTGGCTGCGGCAGTGAGGGGCTATCGCTGCATCATCGTGATGCCAGAGAAGATGAGCTCCGAGAAGGTGGACGTGCTGCGGGCACTGGGGGCTGAGATTGTGAGGACGCCCACCAATGCCAGGTTCGACTCCCCGGAGTCACACGTGGGGGTGGCCTGGCGGCTGAAGAACGAAATCCCCAATTCTCACATCCTAGACCAGTACCGCAACGCCAGCAACCCCCTGGCTCACTACGACACCACCGCTGATGAGATCCTGCAGCAGTGTGATGGGAAGCTGGACATGCTGGTGGCTTCAGTGGGCACGGGCGGCACCATCACGGGCATTGCCAGGAAGCTGAAGGAGAAGTGTCCTGGATGCAGGATCATTGGGGTGGATCCCGAAGGGTCCATCCTCGCAGAGCCGGAGGAGCTGAACCAGACGGAGCAGACAACCTACGAGGTGGAAGGGATCGGCTACGACTTCATCCCCACGGTGCTGGACAGGACGGTGGTGGACAAGTGGTTCAAGAGCAACGATGAGGAGGCGTTCACCTTTGCCCGCATGCTGATCGCGCAAGAGGGGCTGCTGTGCGGTGGCAGTGCTGGCAGCACGGTGGCGGTGGCCGTGAAGGCCGCGCAGGAGCTGCAGGAGGGCCAGCGCTGCGTGGTCATTCTGCCCGACTCAGTGCGGAACTACATGACCAAGTTCCTGAGCGACAGGTGGATGCTGCAGAAGGGCTTTCTGAAGGAGGAGGACCTCACGGAGAAGAAGCCCTGGTGGTGGCACCTCCGTGTTCAGGAGCTGGGCCTGTCAGCCCCGCTGACCGTGCTCCCGACCATCACCTGTGGGCACACCATCGAGATCCTCCGGGAGAAGGGCTTCGACCAGGCGCCCGTGGTGGATGAGGCGGGGGTAATCCTGGGAATGGTGACGCTTGGGAACATGCTCTCGTCCCTGCTTGCCGGGAAGGTGCAGCCGTCAGACCAAGTTGGCAAAGTCATCTACAAGCAGTTCAAACAGATCCGCCTCACGGACACGCTGGGCAGGCTCTCGCACATCCTGGAGATGGACCACTTCGCCCTGGTGGTGCACGAGCAGATCCAGTACCACAGCACCGGGAAGTCCAGTCAGCGGCAGATGGTGTTCGGGGTGGTCACCGCCATTGACTTGCTGAACTTCGTGGCCGCCCAGGAGCGGGACCAGAAGTGA,dna,CBS,GCF_000001405.26,P35520,Protein coding +176,urn:mavedb:00000061-e-1,TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAAGAACAGTGGTCAATGTGCGAAATGGAATGAGCTTGCATGACTGCCTTATGAAAGCACTCAAGGTGAGGGGC,dna,RAF,GCF_000001405.26,P04049,Protein coding +177,urn:mavedb:00000019-a-1,GGCGTCTGGACTAGGAGCTTATTGATAACCTCAGACGTTCCAGAAGCGAGTGTGTGGAACTGCTGAAGGGTGCTTCCTTTTATTCTTCATCCCTAGCCAGCCGCCGGCCCCTGGCCTCACTGGATACTCTAAGACTATTGGTCAAGTTTGCCTTGTCAAGGCTATTGGTCAAGGCAAGGCTGGCCAACCCATGGGTGGAGTTTAGCCAGGGACCGTTTCAGACAGATATTTGCATTGAGATAGTGTGGGGAAGGGGCCCCCAAGAGGATACTGC,dna,HBG1 promoter,GCF_000001405.26,,Regulatory +178,urn:mavedb:00000055-b-1,ATGACGGCCAGCGCACAGCCGCGCGGGCGGCGGCCAGGAGTCGGAGTCGGAGTCGTGGTGACCAGCTGCAAGCATCCGCGTTGCGTCCTCCTGGGGAAGAGGAAAGGCTCGGTTGGAGCTGGCAGTTTCCAACTCCCTGGAGGTCATCTGGAGTTCGGTGAAACCTGGGAAGAATGTGCTCAAAGGGAAACCTGGGAAGAAGCAGCTCTTCACCTGAAAAATGTTCACTTTGCCTCAGTTGTGAATTCTTTCATTGAGAAGGAGAATTACCATTATGTTACTATATTAATGAAAGGAGAAGTGGATGTGACTCATGATTCAGAACCAAAGAATGTAGAGCCTGAAAAAAATGAAAGTTGGGAGTGGGTTCCTTGGGAAGAACTACCTCCCCTGGACCAGCTTTTCTGGGGACTGCGTTGTTTAAAAGAACAAGGCTATGATCCATTTAAAGAAGATCTGAACCATCTGGTGGGATACAAAGGAAATCATCTCTAG,dna,NUDT15,GCF_000001405.26,Q9NV35,Protein coding +179,urn:mavedb:00000057-a-1,ACGGAATATAAGCTGGTGGTGGTGGGCGCCGGCGGTGTGGGCAAGAGTGCGCTGACCATCCAGCTGATCCAGAACCATTTTGTGGACGAATACGACCCCACTATAGAGGATTCCTACCGGAAGCAGGTGGTCATTGATGGGGAGACGTGCCTGTTGGACATCCTGGATACCGCCGGCCAGGAGGAGTACAGCGCCATGCGGGACCAGTACATGCGCACCGGGGAGGGCTTCCTGTGTGTGTTTGCCATCAACAACACCAAGTCTTTTGAGGACATCCACCAGTACAGGGAGCAGATCAAACGGGTGAAGGACTCGGATGACGTGCCCATGGTGCTGGTGGGGAACAAGTGTGACCTGGCTGCACGCACTGTGGAATCTCGGCAGGCTCAGGACCTCGCCCGAAGCTACGGCATCCCCTACATCGAGACCTCGGCCAAGACCCGGCAGGGAGTGGAGGATGCCTTCTACACGTTGGTGCGTGAGATCCGGCAGCAC,dna,Ras,GCF_000001405.26,P01112,Protein coding +180,urn:mavedb:00000097-n-1,CATTCTGCAGATGCTGAGTTTGTGTGTGAACGGACACTGAAATATTTTCTAGGAATTGCGGGAGGAAAATGGGTAGTTAGCTATTTCTGTAAGTATAA,dna,BRCA1 Exon 17,GCF_000001405.13,,Protein coding +181,urn:mavedb:00000001-d-2,ATGGAGCATGCCTTTACCCCGTTGGAGCCCCTGCTTTCCACTGGGAATTTGAAGTACTGCCTTGTAATTCTTAATCAGCCTTTGGACAACTATTTTCGTCATCTTTGGAACAAAGCTCTTTTAAGAGCCTGTGCCGATGGAGGTGCCAACCGCTTATATGATATCACCGAAGGAGAGAGAGAAAGCTTTTTGCCTGAATTCATCAATGGAGACTTTGATTCTATTAGGCCTGAAGTCAGAGAATACTATGCTACTAAGGGATGTGAGCTCATTTCAACTCCTGATCAAGACCACACTGACTTTACTAAGTGCCTTAAAATGCTCCAAAAGAAGATAGAAGAAAAAGACTTAAAGGGAAAGCACAGGTTGCATGTAGACACTGGAATGGAGGGTGATTGGTGTGGCCTTATTCCTGTTGGACAGCCTTGTATGCAGGTTACAACCACAGGCCTCAAGTGGAACCTCACAAATGATGTGCTTGCTTTTGGAACATTGGTCAGTACTTCCAATACCTACGACGGGTCTGGTGTTGTGACTGTGGAAACTGACCACCCACTCCTCTGGACCATGGCCATCAAAAGCTAA,dna,TPK1,GCF_000001405.26,Q9H3S4,Protein coding +182,urn:mavedb:00000017-a-1,GTTGTGAATGCCGCGTCCTGTCCTGGTGACAGGAGAACAATGTTGGTGAACGTCGCAGCGGGTGTCCGAGTGCTCCGTGTGCCCCTGAGAGCGGGTGGGAGCGGAAGCCTGAGCGGCCTGCGGCCTCCGGCGATAGTGTGCTATCTGCCGCTGCAGCGCGCGTCCGCGCGGCCTCTGGGCTATTTCTGGCCAGGCCGCAGCACTGTGGTCGGTGCGGGCGTGGCAGGGGCGGGGCGGCCTTATCGCTCGGCTCTCCCGCCTACGCCTCCCGCTGCAGAGTAAGCCGGGCTGCCGTCTTCTCGCCATGGGCTCCGGTGAGTCTGGAGTCCGGTCGGGCCCCCGGCTGCTCCCTAGGCCGACCCGGGTTGAGAGGAGCTCTGGTCGT,dna,GP1BB promoter,GCF_000001405.26,,Regulatory +183,urn:mavedb:00000005-a-3,ATGCCTTCTGAGACCCCCCAGGCAGAAGTGGGGCCCACAGGCTGCCCCCACCGCTCAGGGCCACACTCGGCGAAGGGGAGCCTGGAGAAGGGGTCCCCAGAGGATAAGGAAGCCAAGGAGCCCCTGTGGATCCGGCCCGATGCTCCGAGCAGGTGCACCTGGCAGCTGGGCCGGCCTGCCTCCGAGTCCCCACATCACCACACTGCCCCGGCAAAATCTCCAAAAATCTTGCCAGATATTCTGAAGAAAATCGGGGACACCCCTATGGTCAGAATCAACAAGATTGGGAAGAAGTTCGGCCTGAAGTGTGAGCTCTTGGCCAAGTGTGAGTTCTTCAACGCGGGCGGGAGCGTGAAGGACCGCATCAGCCTGCGGATGATTGAGGATGCTGAGCGCGACGGGACGCTGAAGCCCGGGGACACGATTATCGAGCCGACATCCGGGAACACCGGGATCGGGCTGGCCCTGGCTGCGGCAGTGAGGGGCTATCGCTGCATCATCGTGATGCCAGAGAAGATGAGCTCCGAGAAGGTGGACGTGCTGCGGGCACTGGGGGCTGAGATTGTGAGGACGCCCACCAATGCCAGGTTCGACTCCCCGGAGTCACACGTGGGGGTGGCCTGGCGGCTGAAGAACGAAATCCCCAATTCTCACATCCTAGACCAGTACCGCAACGCCAGCAACCCCCTGGCTCACTACGACACCACCGCTGATGAGATCCTGCAGCAGTGTGATGGGAAGCTGGACATGCTGGTGGCTTCAGTGGGCACGGGCGGCACCATCACGGGCATTGCCAGGAAGCTGAAGGAGAAGTGTCCTGGATGCAGGATCATTGGGGTGGATCCCGAAGGGTCCATCCTCGCAGAGCCGGAGGAGCTGAACCAGACGGAGCAGACAACCTACGAGGTGGAAGGGATCGGCTACGACTTCATCCCCACGGTGCTGGACAGGACGGTGGTGGACAAGTGGTTCAAGAGCAACGATGAGGAGGCGTTCACCTTTGCCCGCATGCTGATCGCGCAAGAGGGGCTGCTGTGCGGTGGCAGTGCTGGCAGCACGGTGGCGGTGGCCGTGAAGGCCGCGCAGGAGCTGCAGGAGGGCCAGCGCTGCGTGGTCATTCTGCCCGACTCAGTGCGGAACTACATGACCAAGTTCCTGAGCGACAGGTGGATGCTGCAGAAGGGCTTTCTGAAGGAGGAGGACCTCACGGAGAAGAAGCCCTGGTGGTGGCACCTCCGTGTTCAGGAGCTGGGCCTGTCAGCCCCGCTGACCGTGCTCCCGACCATCACCTGTGGGCACACCATCGAGATCCTCCGGGAGAAGGGCTTCGACCAGGCGCCCGTGGTGGATGAGGCGGGGGTAATCCTGGGAATGGTGACGCTTGGGAACATGCTCTCGTCCCTGCTTGCCGGGAAGGTGCAGCCGTCAGACCAAGTTGGCAAAGTCATCTACAAGCAGTTCAAACAGATCCGCCTCACGGACACGCTGGGCAGGCTCTCGCACATCCTGGAGATGGACCACTTCGCCCTGGTGGTGCACGAGCAGATCCAGTACCACAGCACCGGGAAGTCCAGTCAGCGGCAGATGGTGTTCGGGGTGGTCACCGCCATTGACTTGCTGAACTTCGTGGCCGCCCAGGAGCGGGACCAGAAGTGA,dna,CBS,GCF_000001405.26,P35520,Protein coding +184,urn:mavedb:00000083-f-1,AGTTCTTCTCGGGAGCTCCAGCACAGTGAAATGGACAGAAGGGCAGAGCAA,dna,Minigene exon - hnRNP I (PTB) binding site,GCF_000001405.13,,Other noncoding +185,urn:mavedb:00000031-d-1,TCGCGGGGGTGGCCGGGGCCAGGGCTTCCCACGTGCGCAGCAGGACGCAGCGCTGCCTGAAACTCGCGCCGCGAGGAGAGGGCGGGGCCGCGGAAAGGAAGGGGAGGGGCTGGGAGGGCCCGGAGGGGGCTGGGCCGGGGACCCGGGAGGGGTCGGGACGGGGCGGGGTCCGCGCGGAGGAGGCGGAGCTGGAAGGTGAAGGGGCAGGACGGGTGCCCGGGTCCCCAGTCCCTCCGCCACGTGGGAAGCGCGGTCCTGG,dna,TERT promoter,GCF_000001405.26,,Regulatory +186,urn:mavedb:00000106-c-1,MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL,protein,AID,GCF_000001405.26,,Protein coding +187,urn:mavedb:00000020-a-1,CCCCAGAGTGCAGGACTAGGACCCGAGTGGACCTCAGGTCTGGCCAGGTCGCCATTGCCATGGAGACAGCAACAGTCCCCAGCCGCGGGTTCCCTAAGTGACTGGTTACTCTTTAACGTATCCACCCACCTTGGGTGATTAGAAGAATCAATAAGATAACCGGGCGGTGGCAGCTGGCCGCACTCACCGCCTTCCTGGTGGACGGGCTCCTGGTGGCTGTGCTGCTGCTGTGAGCGGGCCCCTGCTCCTCCATGCCCCCAGCTCTCCGGCTGGGTGGGCTTGGCC,dna,HNF4A promoter,GCF_000001405.26,,Regulatory +188,urn:mavedb:00000007-a-1,CTCTGAAGCTCAAAAGCAATGATTTGATAAGGCTTCGATTTTTAACACTTGAATTCCAACACCTTTAAAAATACTAAATGTTTCCCATTTTAAACAAGCCAAGTGAATGACTGAATTCTTAACCAAAAATAAATGTGAAGTAGATTGATATCACTCTTTGTCCATACAGAACATTATATAAATATTCTCTGGCCTTACTATCTAGCAAGGCAGGAAAAATAGATCAATTTGTTCTCACTCATAGGTGGGAATTGAACAATGAGAACACATGGACACAGGAAGGGGAACATCACACATCGGGGCCTGTTGTGGGGTGGGGGGAGGGGGGAGGGATAGCATTAGGAGATATATCTAACGTTAAATGACGTGTTAATGGGAGCAGCACACCAACATGGCACATGTATACATATGTAACAAACTGCATGTTGTGCACATGTACCCTAAAACTTAAAGTATAATAAGAAAAATAGATCAATTTACTCTACATCTGAGATTAAAAAGCAGAAAGACTCACTCACAGAGTTTCAGTATTTGACATTCAGAACCAGAAATAGAGTAACAGCGAGAACTTGAACTATTTCAGTTTAGCCTCCCACCCTCTCTGCTATCACTTCCCAAAA,dna,ECR11 enhancer,GCF_000001405.13,,Regulatory +189,urn:mavedb:00000045-b-1,ATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTGGATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAA,dna,alpha-synuclein,GCF_000001405.10,P37840,Protein coding +190,urn:mavedb:00000048-b-1,GAGGGGATCAGTATATACACTTCAGATAACTACACCGAGGAAATGGGCTCAGGGGACTATGACTCCATGAAGGAACCCTGTTTCCGTGAAGAAAATGCTAATTTCAATAAAATCTTCCTGCCCACCATCTACTCCATCATCTTCTTAACTGGCATTGTGGGCAATGGATTGGTCATCCTGGTCATGGGTTACCAGAAGAAACTGAGAAGCATGACGGACAAGTACAGGCTGCACCTGTCAGTGGCCGACCTCCTCTTTGTCATCACGCTTCCCTTCTGGGCAGTTGATGCCGTGGCAAACTGGTACTTTGGGAACTTCCTATGCAAGGCAGTCCATGTCATCTACACAGTCAACCTCTACAGCAGTGTCCTCATCCTGGCCTTCATCAGTCTGGACCGCTACCTGGCCATCGTCCACGCCACCAACAGTCAGAGGCCAAGGAAGCTGTTGGCTGAAAAGGTGGTCTATGTTGGCGTCTGGATCCCTGCCCTCCTGCTGACTATTCCCGACTTCATCTTTGCCAACGTCAGTGAGGCAGATGACAGATATATCTGTGACCGCTTCTACCCCAATGACTTGTGGGTGGTTGTGTTCCAGTTTCAGCACATCATGGTTGGCCTTATCCTGCCTGGTATTGTCATCCTGTCCTGCTATTGCATTATCATCTCCAAGCTGTCACACTCCAAGGGCCACCAGAAGCGCAAGGCCCTCAAGACCACAGTCATCCTCATCCTGGCTTTCTTCGCCTGTTGGCTGCCTTACTACATTGGGATCAGCATCGACTCCTTCATCCTCCTGGAAATCATCAAGCAAGGGTGTGAGTTTGAGAACACTGTGCACAAGTGGATTTCCATCACCGAGGCCCTAGCTTTCTTCCACTGTTGTCTGAACCCCATCCTCTATGCTTTCCTTGGAGCCAAATTTAAAACCTCTGCCCAGCACGCACTCACCTCTGTGAGCAGAGGGTCCAGCCTCAAGATCCTCTCCAAAGGAAAGCGAGGTGGACATTCATCTGTTTCCACTGAGTCTGAGTCTTCAAGTTTTCACTCCAGC,dna,CXCR4,GCF_000001405.26,P61073,Protein coding +191,urn:mavedb:00000095-a-1,ATGGACTCCTTGGTTGTGTTGGTTCTGTGTTTATCTTGCTTACTATTGCTGAGCCTTTGGAGACAGTCTTCAGGAAGAGGTAAGTTGCCCCCGGGTCCTACACCCCTGCCTGTGATAGGTAATATATTACAGATCGGGATCAAAGATATCAGTAAGAGTCTGACTAATTTGTCCAAAGTGTATGGTCCAGTGTTTACTCTGTACTTTGGCTTGAAACCCATTGTGGTTTTGCACGGATACGAAGCTGTTAAGGAGGCACTAATCGATTTAGGCGAAGAATTCTCTGGAAGAGGCATTTTTCCATTGGCTGAAAGGGCAAACAGAGGTTTCGGTATCGTTTTTAGTAACGGAAAGAAGTGGAAGGAAATTAGAAGATTTAGTTTAATGACTCTGAGAAATTTCGGTATGGGTAAAAGATCAATTGAGGATAGAGTGCAAGAAGAAGCTCGTTGTCTTGTGGAAGAATTAAGGAAAACCAAAGCATCTCCTTGTGACCCCACTTTCATTCTAGGCTGCGCACCGTGTAACGTTATTTGCTCTATTATTTTTCATAAGAGATTTGACTATAAGGATCAACAATTCTTGAATTTAATGGAAAAGTTGAACGAAAATATTAAAATATTGTCATCACCTTGGATTCAGATTTGCAACAACTTCTCACCAATTATCGACTATTTCCCAGGTACCCACAACAAGCTACTGAAGAATGTGGCTTTCATGAAATCTTACATTCTTGAAAAAGTCAAAGAACACCAAGAATCCATGGACATGAACAATCCACAAGATTTCATTGACTGTTTCCTTATGAAAATGGAGAAGGAGAAGCACAACCAACCCTCAGAATTTACCATAGAATCCCTTGAAAATACCGCTGTCGATTTATTTGGCGCTGGAACAGAGACCACTTCAACTACCTTGCGTTACGCATTACTACTATTACTAAAACACCCAGAAGTGACCGCGAAGGTGCAAGAAGAGATTGAGAGAGTGATCGGCAGAAATAGATCTCCTTGTATGCAAGATAGATCCCATATGCCTTATACTGATGCAGTCGTACATGAAGTTCAACGTTACATCGACTTGTTGCCTACCAGCTTGCCGCATGCAGTTACTTGTGATATTAAGTTTAGGAATTACCTTATTCCGAAAGGTACCACTATTTTGATATCTCTTACCTCCGTCTTACACGATAATAAGGAGTTTCCTAATCCAGAAATGTTCGATCCTCATCACTTCCTTGACGAGGGAGGGAATTTCAAAAAAAGTAAATACTTTATGCCATTCTCAGCGGGAAAAAGAATATGCGTAGGCGAAGCCCTGGCGGGAATGGAATTGTTCTTATTCCTGACGTCCATTCTTCAAAACTTTAACTTGAAATCTCTTGTAGATCCTAAAAATTTAGATACAACTCCGGTTGTTAATGGATTTGCATCAGTGCCTCCTTTTTATCAGCTTTGTTTTATACCCGTT,dna,CYP2C9,GCF_000001405.26,,Protein coding +192,urn:mavedb:00000016-a-1,CTCGCCAGCGGTCCGCAGGGCTGGAGACCCACGCCGTGGAGAGGACCAGCCTCAGGTCGCCCCGCCTGGGCCCGCGCCCCGACCTCGCTGCCCCCGCCTCGCCTCTCTGCCCGTGGCGCTTACGGCCACCTTGGCCTCGGGGGCAGGGCATGGGCGGCCCCCGCCAGATCGCCCAGCGCCAGTACTAACTGCCCTCGCTCTGGCCTTCGAGCCCGAAGCCTCTTCTGCGCGCACAACCTAGGCAGTAATCCTAAACTAGCGGGCACCACAGACCAGCTGCAGCCACCCCAACCCAGGGATCACTTCCGGACCCCTCGACCGCCCGGCACCAGCGCGCAAGGGACCCTTCAGCCGGAGACCAGAGTCCAGTCCCGGTCACGAGGCCACCGCCGCTGCCCGCCTCGAGAAGCACCACGCGGGCTGAGCCGTCGGCTAGCGGGTCACTCCCGAGCCTCTGTCTGCACCGCGCCAGCCCCAGACCACGGACGCTGAGCCTCCAGCGCGTGCCAGCCTGGGCCGCTGGGCTCTCGGGGCCAGCCCGCGACGATCCCCTGAGCTCTCCGCAGAAGGGCCGAGCGTCCGTTCCGGGGACGCCAGGCC,dna,FOXE1 promoter,GCF_000001405.26,,Regulatory +193,urn:mavedb:00000029-b-1,TGAACTGGAAAAGCCCTGTCCGGTGAGGGGGCAGAAGGACTCAGCGCCCCTGGACCCCCAAATGCTGCATGAACACATTTTCAGGGGAGCCTGTGCCCCCAGGCGGGGGTCGGGCAGCCCCAGCCCCTCTCCTTTTCCTGGACTCTGGCCGTGCGCGGCAGCCCAGGTGTTTGCTCAGTTGCTGACCCAAAAGTGCTTCATTTTTCGTGCCCGCCCCGCGCCCCGGGCAGGCCAGTCATGTGTTAAGTTGCGCTTCTTTGCTGTGATGTGGGTGGGGGAGGAAGAGTAAACACAGTGCTGGCTCGGCTGCCCTGAGGGTGCTCAATCAAGCACAGGTTTCAAGTCTGGGTTCTGGTGTCCACTCACCCACCCCACCCCCCAAAATCAGACAAATGCTACTTTGTCTAACCTGCTGTGGCCTCTGAGACATGTTCTATTTTTAACCCCTTCTTGGAATTGGCTCTCTTCTTCAAAGGACCAGGTCCTGTTCCTCTTTCTCCCCGACTCCACCCCAGCTCCCTGTGAAGAGAGAGTTAATATATTTGTTTTATTTATTTGCTTTTTGTGTTGGGATGGGTTCGTGTCCAGTCCCGGGGGTCTG,dna,SORT1 enhancer (flipped),GCF_000001405.26,,Regulatory +194,urn:mavedb:00000049-a-5,ATGGTGAACGAAGCCAGAGGAAACAGCAGCCTCAACCCCTGCTTGGAGGGCAGTGCCAGCAGTGGCAGTGAGAGCTCCAAAGATAGTTCGAGATGTTCCACCCCGGGCCTGGACCCCGAGCGGCATGAGAGACTCCGGGAGAAGATGAGGCGGCGATTGGAATCTGGTGACAAGTGGTTCTCCCTGGAATTCTTCCCTCCTCGAACTGCTGAGGGAGCTGTCAATCTCATCTCAAGGTTTGACCGGATGGCAGCAGGTGGCCCCCTCTACATAGACGTGACCTGGCACCCAGCAGGTGACCCTGGCTCAGACAAGGAGACCTCCTCCATGATGATCGCCAGCACCGCCGTGAACTACTGTGGCCTGGAGACCATCCTGCACATGACCTGCTGCCGTCAGCGCCTGGAGGAGATCACGGGCCATCTGCACAAAGCTAAGCAGCTGGGCCTGAAGAACATCATGGCGCTGCGGGGAGACCCAATAGGTGACCAGTGGGAAGAGGAGGAGGGAGGCTTCAACTACGCAGTGGACCTGGTGAAGCACATCCGAAGTGAGTTTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCGAAGCAGGGAGCTTTGAGGCTGACCTGAAGCACTTGAAGGAGAAGGTGTCTGCGGGAGCCGATTTCATCATCACGCAGCTTTTCTTTGAGGCTGACACATTCTTCCGCTTTGTGAAGGCATGCACCGACATGGGCATCACTTGCCCCATCGTCCCCGGGATCTTTCCCATCCAGGGCTACCACTCCCTTCGGCAGCTTGTGAAGCTGTCCAAGCTGGAGGTGCCACAGGAGATCAAGGACGTGATTGAGCCAATCAAAGACAACGATGCTGCCATCCGCAACTATGGCATCGAGCTGGCCGTGAGCCTGTGCCAGGAGCTTCTGGCCAGTGGCTTGGTGCCAGGCCTCCACTTCTACACCCTCAACCGCGAGATGGCTACCACAGAGGTGCTGAAGCGCCTGGGGATGTGGACTGAGGACCCCAGGCGTCCCCTACCCTGGGCTCTCAGCGCCCACCCCAAGCGCCGAGAGGAAGATGTACGTCCCATCTTCTGGGCCTCCAGACCAAAGAGTTACATCTACCGTACCCAGGAGTGGGACGAGTTCCCTAACGGCCGCTGGGGCAATTCCTCTTCCCCTGCCTTTGGGGAGCTGAAGGACTACTACCTCTTCTACCTGAAGAGCAAGTCCCCCAAGGAGGAGCTGCTGAAGATGTGGGGGGAGGAGCTGACCAGTGAAGAAAGTGTCTTTGAAGTCTTCGTTCTTTACCTCTCGGGAGAACCAAACCGGAATGGTCACAAAGTGACTTGCCTGCCCTGGAACGATGAGCCCCTGGCGGCTGAGACCAGCCTGCTGAAGGAGGAGCTGCTGCGGGTGAACCGCCAGGGCATCCTCACCATCAACTCACAGCCCAACATCAACGGGAAGCCGTCCTCCGACCCCATCGTGGGCTGGGGCCCCAGCGGGGGCTATGTCTTCCAGAAGGCCTACTTAGAGTTTTTCACTTCCCGCGAGACAGCGGAAGCACTTCTGCAAGTGCTGAAGAAGTACGAGCTCCGGGTTAATTACCACCTTGTCAATGTGAAGGGTGAAAACATCACCAATGCCCCTGAACTGCAGCCGAATGCTGTCACTTGGGGCATCTTCCCTGGGCGAGAGATCATCCAGCCCACCGTAGTGGATCCCGTCAGCTTCATGTTCTGGAAGGACGAGGCCTTTGCCCTGTGGATTGAGCGGTGGGGAAAGCTGTATGAGGAGGAGTCCCCGTCCCGCACCATCATCCAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAATGACTTCCCACTGGACAACTGCCTCTGGCAGGTGGTGGAAGACACATTGGAGCTTCTCAACAGGCCCACCCAGAATGCGAGAGAAACGGAGGCTCCATGA,dna,MTHFR,GCF_000001405.26,P42898,Protein coding +195,urn:mavedb:00000097-y-1,CTGTCTCCAGCAATTGGGCAGATGTGTGAGGCACCTGTGGTGACCCGAGAGTGGGTGTTGGACAGTGTAGCACTCTACCAGTGCCAGGAGCTGGACACCTACCTGATA,dna,BRCA1 Exon 23,GCF_000001405.13,,Protein coding +196,urn:mavedb:00000005-a-1,ATGCCTTCTGAGACCCCCCAGGCAGAAGTGGGGCCCACAGGCTGCCCCCACCGCTCAGGGCCACACTCGGCGAAGGGGAGCCTGGAGAAGGGGTCCCCAGAGGATAAGGAAGCCAAGGAGCCCCTGTGGATCCGGCCCGATGCTCCGAGCAGGTGCACCTGGCAGCTGGGCCGGCCTGCCTCCGAGTCCCCACATCACCACACTGCCCCGGCAAAATCTCCAAAAATCTTGCCAGATATTCTGAAGAAAATCGGGGACACCCCTATGGTCAGAATCAACAAGATTGGGAAGAAGTTCGGCCTGAAGTGTGAGCTCTTGGCCAAGTGTGAGTTCTTCAACGCGGGCGGGAGCGTGAAGGACCGCATCAGCCTGCGGATGATTGAGGATGCTGAGCGCGACGGGACGCTGAAGCCCGGGGACACGATTATCGAGCCGACATCCGGGAACACCGGGATCGGGCTGGCCCTGGCTGCGGCAGTGAGGGGCTATCGCTGCATCATCGTGATGCCAGAGAAGATGAGCTCCGAGAAGGTGGACGTGCTGCGGGCACTGGGGGCTGAGATTGTGAGGACGCCCACCAATGCCAGGTTCGACTCCCCGGAGTCACACGTGGGGGTGGCCTGGCGGCTGAAGAACGAAATCCCCAATTCTCACATCCTAGACCAGTACCGCAACGCCAGCAACCCCCTGGCTCACTACGACACCACCGCTGATGAGATCCTGCAGCAGTGTGATGGGAAGCTGGACATGCTGGTGGCTTCAGTGGGCACGGGCGGCACCATCACGGGCATTGCCAGGAAGCTGAAGGAGAAGTGTCCTGGATGCAGGATCATTGGGGTGGATCCCGAAGGGTCCATCCTCGCAGAGCCGGAGGAGCTGAACCAGACGGAGCAGACAACCTACGAGGTGGAAGGGATCGGCTACGACTTCATCCCCACGGTGCTGGACAGGACGGTGGTGGACAAGTGGTTCAAGAGCAACGATGAGGAGGCGTTCACCTTTGCCCGCATGCTGATCGCGCAAGAGGGGCTGCTGTGCGGTGGCAGTGCTGGCAGCACGGTGGCGGTGGCCGTGAAGGCCGCGCAGGAGCTGCAGGAGGGCCAGCGCTGCGTGGTCATTCTGCCCGACTCAGTGCGGAACTACATGACCAAGTTCCTGAGCGACAGGTGGATGCTGCAGAAGGGCTTTCTGAAGGAGGAGGACCTCACGGAGAAGAAGCCCTGGTGGTGGCACCTCCGTGTTCAGGAGCTGGGCCTGTCAGCCCCGCTGACCGTGCTCCCGACCATCACCTGTGGGCACACCATCGAGATCCTCCGGGAGAAGGGCTTCGACCAGGCGCCCGTGGTGGATGAGGCGGGGGTAATCCTGGGAATGGTGACGCTTGGGAACATGCTCTCGTCCCTGCTTGCCGGGAAGGTGCAGCCGTCAGACCAAGTTGGCAAAGTCATCTACAAGCAGTTCAAACAGATCCGCCTCACGGACACGCTGGGCAGGCTCTCGCACATCCTGGAGATGGACCACTTCGCCCTGGTGGTGCACGAGCAGATCCAGTACCACAGCACCGGGAAGTCCAGTCAGCGGCAGATGGTGTTCGGGGTGGTCACCGCCATTGACTTGCTGAACTTCGTGGCCGCCCAGGAGCGGGACCAGAAGTGA,dna,CBS,GCF_000001405.26,P35520,Protein coding +197,urn:mavedb:00000097-a-1,AAGTTCATTGGAACAGAAAGAAATGGATTTATCTGCTCTTCGCGTTGAAGAAGTACAAAATGTCATTAATGCTATGCAGAAAATCTTAGAGTGTCCCATCTGGTAA,dna,BRCA1 Exon 2,GCF_000001405.13,,Protein coding +198,urn:mavedb:00000003-a-1,GATTTATCTGCTCTTCGCGTTGAAGAAGTACAAAATGTCATTAATGCTATGCAGAAAATCTTAGAGTGTCCCATCTGCCTGGAGTTGATCAAGGAACCTGTCTCCACAAAGTGTGACCACATATTTTGCAAATTTTGCATGCTGAAACTTCTCAACCAGAAGAAAGGGCCTTCACAGTGTCCTTTATGTAAGAATGATATAACCAAAAGGAGCCTACAAGAAAGTACGAGATTTAGTCAACTTGTTGAAGAGCTATTGAAAATCATTTGTGCTTTTCAGCTTGACACAGGTTTGGAGTATGCAAACAGCTATAATTTTGCAAAAAAGGAAAATAACTCTCCTGAACATCTAAAAGATGAAGTTTCTATCATCCAAAGTATGGGCTACAGAAACCGTGCCAAAAGACTTCTACAGAGTGAACCCGAAAATCCTTCCTTGCAGGAAACCAGTCTCAGTGTCCAACTCTCTAACCTTGGAACTGTGAGAACTCTGAGGACAAAGCAGCGGATACAACCTCAAAGGACGTCTGTCTACATTGAATTGGGATCTGATTCTTCTGAAGATACCGTTAATAAGGCAACTTATTGCAGTGTGGGAGATCAAGAATTGTTACAAATCACCCCTCAAGGAACCAGGGATGAAATCAGTTTGGATTCTGCAAAAAAGGCTGCTTGTGAATTTTCTGAGACGGATGTAACAAATACTGAACATCATCAACCCAGTAATAATGATTTGAACACCACTGAGAAGCGTGCAGCTGAGAGGCATCCAGAAAAGTATCAGGGTAGTTCTGTTTCAAACTTGCATGTGGAGCCATGTGGCACAAATACTCATGCCAGCTCATTACAGCATGAGAACAGCAGTTTATTACTCACTAAAGACAGAATGAATGTAGAAAAGGCTGAGTTC,dna,BRCA1 RING domain,GCF_000001405.26,,Protein coding +199,urn:mavedb:00000030-a-1,AGGTTCTGTTTCTTGCTTAGTCACTTTCTGTTTGAACAAAATTGGAATTTCCTTTTTGGATCTGTTTCTTTAATTGTAAATTGAATCGGACTAAAACCTTTCCAATTTTTTCACATGTGAAGACATACACAAAAGTTTTATTGGAGGGTTGCACATGTGAAAGAAAAAGGGAGAAAGCAGGATTGAGCAGGGGGAGCCGTCAGATGGTAATGCAGATGTGATGAGATCTCTGCCGGACCAAAGAGAAGATTCCTTTTTAAATGGTGACAAATTCATGGGCTTTCTCTGCCTCAAAACCTAGCACAGCTGTTATTTACTGAACAATTAGAGAGCTAAGCACTTTTTAGATACTATATAATTTAATTGCCGTATGAGGCACCCTTAGTTTTCAGACGAGAAACCACAGTTACAGGGAAGGCAAGTAACTTAGTCAATGTCAGATAACTAGGAAAAGGTTAGAGGGGCCCTGGACACAGGCCTGTGTGACTGAGAAGCTTGGGCACTTCACTGCTACATTTCATCTCTTCGCTATAAACATTTTAGCTTTTTGTGTTTGCTGACTGGCAACAATACATAGTGAAAGTTCTAATAATTTGTAAT,dna,TCF7L2 enhancer,GCF_000001405.26,,Regulatory +200,urn:mavedb:00000005-a-4,ATGCCTTCTGAGACCCCCCAGGCAGAAGTGGGGCCCACAGGCTGCCCCCACCGCTCAGGGCCACACTCGGCGAAGGGGAGCCTGGAGAAGGGGTCCCCAGAGGATAAGGAAGCCAAGGAGCCCCTGTGGATCCGGCCCGATGCTCCGAGCAGGTGCACCTGGCAGCTGGGCCGGCCTGCCTCCGAGTCCCCACATCACCACACTGCCCCGGCAAAATCTCCAAAAATCTTGCCAGATATTCTGAAGAAAATCGGGGACACCCCTATGGTCAGAATCAACAAGATTGGGAAGAAGTTCGGCCTGAAGTGTGAGCTCTTGGCCAAGTGTGAGTTCTTCAACGCGGGCGGGAGCGTGAAGGACCGCATCAGCCTGCGGATGATTGAGGATGCTGAGCGCGACGGGACGCTGAAGCCCGGGGACACGATTATCGAGCCGACATCCGGGAACACCGGGATCGGGCTGGCCCTGGCTGCGGCAGTGAGGGGCTATCGCTGCATCATCGTGATGCCAGAGAAGATGAGCTCCGAGAAGGTGGACGTGCTGCGGGCACTGGGGGCTGAGATTGTGAGGACGCCCACCAATGCCAGGTTCGACTCCCCGGAGTCACACGTGGGGGTGGCCTGGCGGCTGAAGAACGAAATCCCCAATTCTCACATCCTAGACCAGTACCGCAACGCCAGCAACCCCCTGGCTCACTACGACACCACCGCTGATGAGATCCTGCAGCAGTGTGATGGGAAGCTGGACATGCTGGTGGCTTCAGTGGGCACGGGCGGCACCATCACGGGCATTGCCAGGAAGCTGAAGGAGAAGTGTCCTGGATGCAGGATCATTGGGGTGGATCCCGAAGGGTCCATCCTCGCAGAGCCGGAGGAGCTGAACCAGACGGAGCAGACAACCTACGAGGTGGAAGGGATCGGCTACGACTTCATCCCCACGGTGCTGGACAGGACGGTGGTGGACAAGTGGTTCAAGAGCAACGATGAGGAGGCGTTCACCTTTGCCCGCATGCTGATCGCGCAAGAGGGGCTGCTGTGCGGTGGCAGTGCTGGCAGCACGGTGGCGGTGGCCGTGAAGGCCGCGCAGGAGCTGCAGGAGGGCCAGCGCTGCGTGGTCATTCTGCCCGACTCAGTGCGGAACTACATGACCAAGTTCCTGAGCGACAGGTGGATGCTGCAGAAGGGCTTTCTGAAGGAGGAGGACCTCACGGAGAAGAAGCCCTGGTGGTGGCACCTCCGTGTTCAGGAGCTGGGCCTGTCAGCCCCGCTGACCGTGCTCCCGACCATCACCTGTGGGCACACCATCGAGATCCTCCGGGAGAAGGGCTTCGACCAGGCGCCCGTGGTGGATGAGGCGGGGGTAATCCTGGGAATGGTGACGCTTGGGAACATGCTCTCGTCCCTGCTTGCCGGGAAGGTGCAGCCGTCAGACCAAGTTGGCAAAGTCATCTACAAGCAGTTCAAACAGATCCGCCTCACGGACACGCTGGGCAGGCTCTCGCACATCCTGGAGATGGACCACTTCGCCCTGGTGGTGCACGAGCAGATCCAGTACCACAGCACCGGGAAGTCCAGTCAGCGGCAGATGGTGTTCGGGGTGGTCACCGCCATTGACTTGCTGAACTTCGTGGCCGCCCAGGAGCGGGACCAGAAGTGA,dna,CBS,GCF_000001405.26,P35520,Protein coding +201,urn:mavedb:00000034-a-1,TGAGATATGGCTTCATTTTCTGTAATAAACACTAAGATCAAAACATGACCCAAGTTAAATTTCCTTGCAGGGTTCCCAGCAGGGGCTTCCCTTTTGTCTGTGATTTCCTCTCACCCACCAGAACCAGGCCAAATATGCGCATGTGCCACTAACACTAAGCAGCACTTCCTTAATCACTCATTTCCAACAATTTATGGATCATCAGTGGCAAAAAACGAGCAAAAATAATGAAAGAATGCAATGAAAGCTCGTGGAGACAGAGGCTGGACTTCCTACTCACTCTGTGTCTCTTTAAGATGGAGGCCTGATACAAATTAGCCACTGGGGGGAAAAAGTCATCTGGTCATAAAATACAGTACAAGGTCACTTTTATGTAAGTTTGCCAAAAGGGACATAAACCAGGACAATTTCAAACTGTGACACAGGATAGAAACATATTAAAAAAATCTTTGTTCCTCCTCTATTGTGCTGTCATGTTGCTCAGCA,dna,ZRS enhancer,GCF_000001405.26,,Regulatory +202,urn:mavedb:00000023-a-2,AGCTCTTCACCGGAGACCCAAATACAACAAATCAAGTCGCCTGCCCTGGCGACACTTTCGAAGGACTGGAGTGGGAATCAGAGCTTCACGGGTTAAAAAGCCGATGTCACATCGGCCGTTCGAAACTCCTCCTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGACGTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGC,dna,LDLR promoter,GCF_000001405.26,,Regulatory +203,urn:mavedb:00000002-a-1,GACGTTCCACTGCCGGCTGGTTGGGAAATGGCTAAAACTAGTTCTGGTCAGCGTTACTTCCTGAACCACATCGACCAGACCACCACGTGGCAGGACCCGCGT,dna,hYAP65 WW domain,GCF_000001405.26,P46937,Protein coding +204,urn:mavedb:00000107-a-1,MDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCGQFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGAVLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSIYVMGLVLEWIKNNGGAAAMEKLSSIKSQTIYEIIDNSQGFYVCPVEPQNRSKMNIPFRIGNAKGDDALEKRFLDKALELNMLSLKGHRSVGGIRASLYNAVTIEDVQKLAAFMKKFLEMHQL,protein,PSAT1,GCF_000001405.26,,Protein coding +205,urn:mavedb:00000103-d-1,MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS,protein,MAPK1,GCF_000001405.26,,Protein coding +206,urn:mavedb:00000029-a-2,GAACTGGAAAAGCCCTGTCCGGTGAGGGGGCAGAAGGACTCAGCGCCCCTGGACCCCCAAATGCTGCATGAACACATTTTCAGGGGAGCCTGTGCCCCCAGGCGGGGGTCGGGCAGCCCCAGCCCCTCTCCTTTTCCTGGACTCTGGCCGTGCGCGGCAGCCCAGGTGTTTGCTCAGTTGCTGACCCAAAAGTGCTTCATTTTTCGTGCCCGCCCCGCGCCCCGGGCAGGCCAGTCATGTGTTAAGTTGCGCTTCTTTGCTGTGATGTGGGTGGGGGAGGAAGAGTAAACACAGTGCTGGCTCGGCTGCCCTGAGGGTGCTCAATCAAGCACAGGTTTCAAGTCTGGGTTCTGGTGTCCACTCACCCACCCCACCCCCCAAAATCAGACAAATGCTACTTTGTCTAACCTGCTGTGGCCTCTGAGACATGTTCTATTTTTAACCCCTTCTTGGAATTGGCTCTCTTCTTCAAAGGACCAGGTCCTGTTCCTCTTTCTCCCCGACTCCACCCCAGCTCCCTGTGAAGAGAGAGTTAATATATTTGTTTTATTTATTTGCTTTTTGTGTTGGGATGGGTTCGTGTCCAGTCCCGGGGGTCTG,dna,SORT1 enhancer,GCF_000001405.26,,Regulatory +207,urn:mavedb:00000061-b-1,TCTAAGACAAGCAACACTATCCGTGTTTTCTTGCCGAACAAGCAAAGAACAGTGGTCAATGTGCGAAATGGAATGAGCTTGCATGACTGCCTTATGAAAGCACTCAAGGTGAGGGGC,dna,RAF,GCF_000001405.26,P04049,Protein coding +208,urn:mavedb:00000097-q-1,TTTCTTTCAGCATGATTTTGAAGTCAGAGGAGATGTGGTCAATGGAAGAAACCACCAAGGTCCAAAGCGAGCAAGAGAATCCCAGGACAGAAAGGTAAAGCTCC,dna,BRCA1 Exon 19,GCF_000001405.13,,Protein coding diff --git a/notebooks/analysis/results/vrs_mappings_noncoding.pickle b/notebooks/analysis/results/vrs_mappings_noncoding.pickle new file mode 100644 index 0000000..5e743cd Binary files /dev/null and b/notebooks/analysis/results/vrs_mappings_noncoding.pickle differ