diff --git a/python/tvm/relay/op/strategy/arm_cpu.py b/python/tvm/relay/op/strategy/arm_cpu.py
index a2079f9aa744..7f0e0db7185d 100644
--- a/python/tvm/relay/op/strategy/arm_cpu.py
+++ b/python/tvm/relay/op/strategy/arm_cpu.py
@@ -162,14 +162,11 @@ def conv2d_strategy_arm_cpu(attrs, inputs, out_type, target):
             )
         elif layout == "NHWC":
             if isa.has_dsp_support and kernel_layout == "HWOI":
-                # TODO(mehrdadh): Only integer type due to
-                # https://github.com/apache/tvm/issues/11351
-                if data.dtype in ["int8", "int16"] and out_dtype == "int32":
-                    strategy.add_implementation(
-                        wrap_compute_conv2d(topi.arm_cpu.conv2d_nhwc_dsp),
-                        wrap_topi_schedule(topi.arm_cpu.schedule_conv2d_nhwc_dsp),
-                        name="conv2d_nhwc_dsp.arm_cpu",
-                    )
+                strategy.add_implementation(
+                    wrap_compute_conv2d(topi.arm_cpu.conv2d_nhwc_dsp),
+                    wrap_topi_schedule(topi.arm_cpu.schedule_conv2d_nhwc_dsp),
+                    name="conv2d_nhwc_dsp.arm_cpu",
+                )
             elif kernel_layout == "HWIO":
                 is_aarch64 = topi.arm_cpu.arm_utils.is_aarch64_arm()
                 has_dot_prod = topi.arm_cpu.arm_utils.is_dotprod_available()
diff --git a/tests/micro/zephyr/conftest.py b/tests/micro/zephyr/conftest.py
index 0cfeed77abe2..997237d370a5 100644
--- a/tests/micro/zephyr/conftest.py
+++ b/tests/micro/zephyr/conftest.py
@@ -79,3 +79,18 @@ def temp_dir(board, tvm_debug):
     keep_for_debug = tvm_debug if tvm_debug else None
     test_temp_dir = tempdir(custom_path=board_workspace, keep_for_debug=keep_for_debug)
     return test_temp_dir
+
+
+@pytest.fixture(autouse=True)
+def skip_by_board(request, board):
+    """Skip test if board is in the list."""
+    if request.node.get_closest_marker("skip_boards"):
+        if board in request.node.get_closest_marker("skip_boards").args[0]:
+            pytest.skip("skipped on this board: {}".format(board))
+
+
+def pytest_configure(config):
+    config.addinivalue_line(
+        "markers",
+        "skip_by_board(board): skip test for the given board",
+    )
diff --git a/tests/micro/zephyr/test_zephyr.py b/tests/micro/zephyr/test_zephyr.py
index 0ea603837714..af5598cda8c7 100644
--- a/tests/micro/zephyr/test_zephyr.py
+++ b/tests/micro/zephyr/test_zephyr.py
@@ -32,6 +32,7 @@
 from tvm.relay.testing import byoc
 from tvm.contrib import utils
 from tvm.micro.testing import check_tune_log
+from tvm.target import arm_isa
 
 import test_utils
 
@@ -87,6 +88,7 @@ def _make_add_sess(temp_dir, model, zephyr_board, west_cmd, build_config, dtype=
 
 # The same test code can be executed on both the QEMU simulation and on real hardware.
 @tvm.testing.requires_micro
+@pytest.mark.skip_boards(["mps2_an521"])
 def test_add_uint(temp_dir, board, west_cmd, tvm_debug):
     """Test compiling the on-device runtime."""
 
@@ -112,6 +114,7 @@ def test_basic_add(sess):
 
 # The same test code can be executed on both the QEMU simulation and on real hardware.
 @tvm.testing.requires_micro
+@pytest.mark.skip_boards(["mps2_an521"])
 def test_add_float(temp_dir, board, west_cmd, tvm_debug):
     """Test compiling the on-device runtime."""
     model = test_utils.ZEPHYR_BOARDS[board]
@@ -138,6 +141,7 @@ def test_basic_add(sess):
 
 
 @tvm.testing.requires_micro
+@pytest.mark.skip_boards(["mps2_an521"])
 def test_platform_timer(temp_dir, board, west_cmd, tvm_debug):
     """Test compiling the on-device runtime."""
 
@@ -167,6 +171,7 @@ def test_basic_add(sess):
 
 
 @tvm.testing.requires_micro
+@pytest.mark.skip_boards(["mps2_an521"])
 def test_relay(temp_dir, board, west_cmd, tvm_debug):
     """Testing a simple relay graph"""
     model = test_utils.ZEPHYR_BOARDS[board]
@@ -199,6 +204,7 @@ def test_relay(temp_dir, board, west_cmd, tvm_debug):
 
 
 @tvm.testing.requires_micro
+@pytest.mark.skip_boards(["mps2_an521"])
 def test_onnx(temp_dir, board, west_cmd, tvm_debug):
     """Testing a simple ONNX model."""
     model = test_utils.ZEPHYR_BOARDS[board]
@@ -279,6 +285,7 @@ def check_result(
 
 
 @tvm.testing.requires_micro
+@pytest.mark.skip_boards(["mps2_an521"])
 def test_byoc_microtvm(temp_dir, board, west_cmd, tvm_debug):
     """This is a simple test case to check BYOC capabilities of microTVM"""
     model = test_utils.ZEPHYR_BOARDS[board]
@@ -359,6 +366,7 @@ def _make_add_sess_with_shape(temp_dir, model, zephyr_board, west_cmd, shape, bu
     ],
 )
 @tvm.testing.requires_micro
+@pytest.mark.skip_boards(["mps2_an521"])
 def test_rpc_large_array(temp_dir, board, west_cmd, tvm_debug, shape):
     """Test large RPC array transfer."""
     model = test_utils.ZEPHYR_BOARDS[board]
@@ -511,6 +519,11 @@ def test_schedule_build_with_cmsis_dependency(temp_dir, board, west_cmd, tvm_deb
     """
     model = test_utils.ZEPHYR_BOARDS[board]
     build_config = {"debug": tvm_debug}
+    target = tvm.target.target.micro(model, options=["-keys=arm_cpu,cpu"])
+
+    isa = arm_isa.IsaAnalyzer(target)
+    if not isa.has_dsp_support:
+        pytest.skip(f"ISA does not support DSP. target: {target}")
 
     # Create a Relay conv2d
     data_shape = (1, 16, 16, 3)
@@ -530,7 +543,6 @@ def test_schedule_build_with_cmsis_dependency(temp_dir, board, west_cmd, tvm_deb
     ir_mod = tvm.IRModule.from_expr(func)
 
     runtime = Runtime("crt", {"system-lib": True})
-    target = tvm.target.target.micro(model, options=["-keys=arm_cpu,cpu"])
 
     with tvm.transform.PassContext(opt_level=3, config={"tir.disable_vectorize": True}):
         mod = tvm.relay.build(ir_mod, target=target, runtime=runtime)
diff --git a/tests/micro/zephyr/test_zephyr_aot.py b/tests/micro/zephyr/test_zephyr_aot.py
index 87c7dc92fbda..9a8ff773973d 100644
--- a/tests/micro/zephyr/test_zephyr_aot.py
+++ b/tests/micro/zephyr/test_zephyr_aot.py
@@ -39,6 +39,7 @@
 
 
 @tvm.testing.requires_micro
+@pytest.mark.skip_boards(["mps2_an521"])
 def test_tflite(temp_dir, board, west_cmd, tvm_debug):
     """Testing a TFLite model."""
     model = test_utils.ZEPHYR_BOARDS[board]
@@ -94,6 +95,7 @@ def test_tflite(temp_dir, board, west_cmd, tvm_debug):
 
 
 @tvm.testing.requires_micro
+@pytest.mark.skip_boards(["mps2_an521"])
 def test_qemu_make_fail(temp_dir, board, west_cmd, tvm_debug):
     """Testing QEMU make fail."""
     if board not in ["qemu_x86", "mps2_an521", "mps3_an547"]:
diff --git a/tests/micro/zephyr/test_zephyr_armv7m.py b/tests/micro/zephyr/test_zephyr_armv7m.py
index 47b78994e039..de3af89b16b4 100644
--- a/tests/micro/zephyr/test_zephyr_armv7m.py
+++ b/tests/micro/zephyr/test_zephyr_armv7m.py
@@ -103,6 +103,7 @@ def _apply_desired_layout_no_simd(relay_mod):
 
 
 @tvm.testing.requires_micro
+@pytest.mark.skip_boards(["mps2_an521"])
 def test_armv7m_intrinsic(temp_dir, board, west_cmd, tvm_debug):
     """Testing a ARM v7m SIMD extension."""
 
diff --git a/tests/scripts/task_python_microtvm.sh b/tests/scripts/task_python_microtvm.sh
index d13ee91a0ba8..96c3c7b75a16 100755
--- a/tests/scripts/task_python_microtvm.sh
+++ b/tests/scripts/task_python_microtvm.sh
@@ -28,6 +28,7 @@ make cython3
 run_pytest ctypes python-microtvm-zephyr-qemu_x86 tests/micro/zephyr --zephyr-board=qemu_x86
 run_pytest ctypes python-microtvm-zephyr-qemu_riscv32 tests/micro/zephyr --zephyr-board=qemu_riscv32
 run_pytest ctypes python-microtvm-zephyr-qemu_riscv64 tests/micro/zephyr --zephyr-board=qemu_riscv64
+run_pytest ctypes python-microtvm-zephyr-mps2_an521 tests/micro/zephyr --zephyr-board=mps2_an521
 
 # Arduino
 run_pytest ctypes python-microtvm-arduino apps/microtvm/arduino/template_project/tests