diff --git a/hbase-server/src/main/java/org/apache/hadoop/hbase/regionserver/HRegionServer.java b/hbase-server/src/main/java/org/apache/hadoop/hbase/regionserver/HRegionServer.java
index 1c5940ca9aed..f9f841181064 100644
--- a/hbase-server/src/main/java/org/apache/hadoop/hbase/regionserver/HRegionServer.java
+++ b/hbase-server/src/main/java/org/apache/hadoop/hbase/regionserver/HRegionServer.java
@@ -1638,8 +1638,9 @@ private static class CompactionChecker extends ScheduledChore {
     @Override
     protected void chore() {
       for (Region r : this.instance.onlineRegions.values()) {
-        // Skip compaction if region is read only
-        if (r == null || r.isReadOnly()) {
+        // If region is read only or compaction is disabled at table level, there's no need to
+        // iterate through region's stores
+        if (r == null || r.isReadOnly() || !r.getTableDescriptor().isCompactionEnabled()) {
           continue;
         }