diff --git a/airflow/providers/google/provider.yaml b/airflow/providers/google/provider.yaml
index 46d82050ffc1..d69b3f8fd6e2 100644
--- a/airflow/providers/google/provider.yaml
+++ b/airflow/providers/google/provider.yaml
@@ -138,7 +138,9 @@ dependencies:
   - google-cloud-pubsub>=2.19.0
   - google-cloud-redis>=2.12.0
   - google-cloud-secret-manager>=2.16.0
-  - google-cloud-spanner>=3.11.1
+  # Google Cloud spanner 3.49.0 is excluded due to a bug in the library (missing grpc_interceptor)
+  # See https://github.com/googleapis/python-spanner/issues/1193
+  - google-cloud-spanner>=3.11.1,!=3.49.0
   - google-cloud-speech>=2.18.0
   - google-cloud-storage>=2.7.0
   - google-cloud-storage-transfer>=1.4.1
diff --git a/generated/provider_dependencies.json b/generated/provider_dependencies.json
index 7f8566689221..a091b47d9d90 100644
--- a/generated/provider_dependencies.json
+++ b/generated/provider_dependencies.json
@@ -643,7 +643,7 @@
       "google-cloud-redis>=2.12.0",
       "google-cloud-run>=0.10.0",
       "google-cloud-secret-manager>=2.16.0",
-      "google-cloud-spanner>=3.11.1",
+      "google-cloud-spanner>=3.11.1,!=3.49.0",
       "google-cloud-speech>=2.18.0",
       "google-cloud-storage-transfer>=1.4.1",
       "google-cloud-storage>=2.7.0",