diff --git a/__tests__/integration/snapshots/tooltip/alphabet-interval-brush-tooltip/step1.html b/__tests__/integration/snapshots/tooltip/alphabet-interval-brush-tooltip/step1.html
new file mode 100644
index 0000000000..ec747fa47d
--- /dev/null
+++ b/__tests__/integration/snapshots/tooltip/alphabet-interval-brush-tooltip/step1.html
@@ -0,0 +1 @@
+null
\ No newline at end of file
diff --git a/__tests__/plots/tooltip/alphabet-interval-brush-tooltip.ts b/__tests__/plots/tooltip/alphabet-interval-brush-tooltip.ts
new file mode 100644
index 0000000000..2a16ccca0c
--- /dev/null
+++ b/__tests__/plots/tooltip/alphabet-interval-brush-tooltip.ts
@@ -0,0 +1,48 @@
+import { CustomEvent } from '@antv/g';
+import { G2Spec, PLOT_CLASS_NAME } from '../../../src';
+import { brush } from '../interaction/penguins-point-brush';
+
+export function alphabetIntervalBrushTooltip(): G2Spec {
+  return {
+    type: 'interval',
+    transform: [{ type: 'sortX', by: 'y', reverse: true }],
+    data: {
+      type: 'fetch',
+      value: 'data/alphabet.csv',
+    },
+    encode: {
+      x: 'letter',
+      y: 'frequency',
+      color: 'steelblue',
+    },
+    state: {
+      active: { fill: 'red' },
+    },
+    interaction: {
+      brushHighlight: true,
+    },
+  };
+}
+
+alphabetIntervalBrushTooltip.steps = ({ canvas }) => {
+  const { document } = canvas;
+  const plot = document.getElementsByClassName(PLOT_CLASS_NAME)[0];
+  return [
+    {
+      skip: true,
+      changeState: () => {
+        brush(plot, 400, 300, 600, 400);
+      },
+    },
+    {
+      changeState: () => {
+        plot.dispatchEvent(
+          new CustomEvent('pointerover', {
+            offsetX: 500,
+            offsetY: 360,
+          }),
+        );
+      },
+    },
+  ];
+};
diff --git a/__tests__/plots/tooltip/index.ts b/__tests__/plots/tooltip/index.ts
index 0baf98854f..4a8dd5c924 100644
--- a/__tests__/plots/tooltip/index.ts
+++ b/__tests__/plots/tooltip/index.ts
@@ -57,3 +57,4 @@ export { profitIntervalLegendFilterOrdinal } from './profit-interval-legend-filt
 export { aaplLineSliderFilter } from './appl-line-slider-filter';
 export { aaplLineAreaBasicSample } from './aapl-line-area-basic-sample';
 export { aaplAreaMissingDataTranspose } from './aapl-area-missing-data-transpose';
+export { alphabetIntervalBrushTooltip } from './alphabet-interval-brush-tooltip';
diff --git a/src/interaction/tooltip.ts b/src/interaction/tooltip.ts
index e62299f348..be03c695a8 100644
--- a/src/interaction/tooltip.ts
+++ b/src/interaction/tooltip.ts
@@ -497,7 +497,10 @@ export function tooltip(
   const pointerover = throttle(
     (event) => {
       const { target: element } = event;
-      if (!elementSet.has(element)) return;
+      if (!elementSet.has(element)) {
+        hideTooltip(root, single);
+        return;
+      }
       const k = groupKey(element);
       const group = keyGroup.get(k);
       const data =