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DESCRIPTION
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DESCRIPTION
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Package: ACMEeqtl
Type: Package
Title: Estimation of Interpretable eQTL Effect Sizes Using a Log of Linear Model
Version: 1.7
Date: 2018-05-08
Authors@R: c(person("Andrey A", "Shabalin",
role = c("aut", "cre"),
email = "[email protected]",
comment = c(ORCID = "0000-0003-0309-6821")),
person("John", "Palowitch",
role = c("aut"),
comment = c(ORCID = "0000-0002-1419-3056")))
Description: We use a non-linear model, termed ACME,
that reflects a parsimonious biological model for
allelic contributions of cis-acting eQTLs.
With non-linear least-squares algorithm we
estimate maximum likelihood parameters. The ACME model
provides interpretable effect size estimates and
p-values with well controlled Type-I error.
Includes both R and (much faster) C implementations.
For more details see Palowitch et al. (2017) <doi:10.1111/biom.12810>.
BugReports: https://github.com/andreyshabalin/ACMEeqtl/issues
Depends: R (>= 3.3.0), filematrix
Imports: parallel
Suggests: knitr, rmarkdown, pander
URL: https://github.com/andreyshabalin/ACMEeqtl
License: LGPL-3
VignetteBuilder: knitr