diff --git a/Include/internal/pycore_list.h b/Include/internal/pycore_list.h
index 92cab731bc253bb..2a82912e41d5571 100644
--- a/Include/internal/pycore_list.h
+++ b/Include/internal/pycore_list.h
@@ -56,8 +56,6 @@ typedef struct {
 
 PyAPI_FUNC(PyObject *)_PyList_FromArraySteal(PyObject *const *src, Py_ssize_t n);
 
-PyAPI_FUNC(int) _PyList_Contains(PyObject *aa, PyObject *el);
-
 #ifdef __cplusplus
 }
 #endif
diff --git a/Include/internal/pycore_opcode_metadata.h b/Include/internal/pycore_opcode_metadata.h
index 4c691d6a922862e..efb731f18632837 100644
--- a/Include/internal/pycore_opcode_metadata.h
+++ b/Include/internal/pycore_opcode_metadata.h
@@ -153,14 +153,8 @@ int _PyOpcode_num_popped(int opcode, int oparg)  {
             return 2;
         case CONTAINS_OP_DICT:
             return 2;
-        case CONTAINS_OP_LIST:
-            return 2;
         case CONTAINS_OP_SET:
             return 2;
-        case CONTAINS_OP_STR:
-            return 2;
-        case CONTAINS_OP_TUPLE:
-            return 2;
         case CONVERT_VALUE:
             return 1;
         case COPY:
@@ -588,14 +582,8 @@ int _PyOpcode_num_pushed(int opcode, int oparg)  {
             return 1;
         case CONTAINS_OP_DICT:
             return 1;
-        case CONTAINS_OP_LIST:
-            return 1;
         case CONTAINS_OP_SET:
             return 1;
-        case CONTAINS_OP_STR:
-            return 1;
-        case CONTAINS_OP_TUPLE:
-            return 1;
         case CONVERT_VALUE:
             return 1;
         case COPY:
@@ -1024,10 +1012,7 @@ const struct opcode_metadata _PyOpcode_opcode_metadata[268] = {
     [COMPARE_OP_STR] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_EXIT_FLAG | HAS_ESCAPES_FLAG },
     [CONTAINS_OP] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG },
     [CONTAINS_OP_DICT] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG },
-    [CONTAINS_OP_LIST] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG },
     [CONTAINS_OP_SET] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG },
-    [CONTAINS_OP_STR] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG },
-    [CONTAINS_OP_TUPLE] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG },
     [CONVERT_VALUE] = { true, INSTR_FMT_IB, HAS_ARG_FLAG | HAS_ERROR_FLAG },
     [COPY] = { true, INSTR_FMT_IB, HAS_ARG_FLAG | HAS_PURE_FLAG },
     [COPY_FREE_VARS] = { true, INSTR_FMT_IB, HAS_ARG_FLAG },
@@ -1251,10 +1236,7 @@ _PyOpcode_macro_expansion[256] = {
     [COMPARE_OP_STR] = { .nuops = 2, .uops = { { _GUARD_BOTH_UNICODE, 0, 0 }, { _COMPARE_OP_STR, 0, 0 } } },
     [CONTAINS_OP] = { .nuops = 1, .uops = { { _CONTAINS_OP, 0, 0 } } },
     [CONTAINS_OP_DICT] = { .nuops = 1, .uops = { { _CONTAINS_OP_DICT, 0, 0 } } },
-    [CONTAINS_OP_LIST] = { .nuops = 1, .uops = { { _CONTAINS_OP_LIST, 0, 0 } } },
     [CONTAINS_OP_SET] = { .nuops = 1, .uops = { { _CONTAINS_OP_SET, 0, 0 } } },
-    [CONTAINS_OP_STR] = { .nuops = 1, .uops = { { _CONTAINS_OP_STR, 0, 0 } } },
-    [CONTAINS_OP_TUPLE] = { .nuops = 1, .uops = { { _CONTAINS_OP_TUPLE, 0, 0 } } },
     [CONVERT_VALUE] = { .nuops = 1, .uops = { { _CONVERT_VALUE, 0, 0 } } },
     [COPY] = { .nuops = 1, .uops = { { _COPY, 0, 0 } } },
     [COPY_FREE_VARS] = { .nuops = 1, .uops = { { _COPY_FREE_VARS, 0, 0 } } },
@@ -1429,10 +1411,7 @@ const char *_PyOpcode_OpName[268] = {
     [COMPARE_OP_STR] = "COMPARE_OP_STR",
     [CONTAINS_OP] = "CONTAINS_OP",
     [CONTAINS_OP_DICT] = "CONTAINS_OP_DICT",
-    [CONTAINS_OP_LIST] = "CONTAINS_OP_LIST",
     [CONTAINS_OP_SET] = "CONTAINS_OP_SET",
-    [CONTAINS_OP_STR] = "CONTAINS_OP_STR",
-    [CONTAINS_OP_TUPLE] = "CONTAINS_OP_TUPLE",
     [CONVERT_VALUE] = "CONVERT_VALUE",
     [COPY] = "COPY",
     [COPY_FREE_VARS] = "COPY_FREE_VARS",
@@ -1685,10 +1664,7 @@ const uint8_t _PyOpcode_Deopt[256] = {
     [COMPARE_OP_STR] = COMPARE_OP,
     [CONTAINS_OP] = CONTAINS_OP,
     [CONTAINS_OP_DICT] = CONTAINS_OP,
-    [CONTAINS_OP_LIST] = CONTAINS_OP,
     [CONTAINS_OP_SET] = CONTAINS_OP,
-    [CONTAINS_OP_STR] = CONTAINS_OP,
-    [CONTAINS_OP_TUPLE] = CONTAINS_OP,
     [CONVERT_VALUE] = CONVERT_VALUE,
     [COPY] = COPY,
     [COPY_FREE_VARS] = COPY_FREE_VARS,
@@ -1875,6 +1851,9 @@ const uint8_t _PyOpcode_Deopt[256] = {
     case 146: \
     case 147: \
     case 148: \
+    case 221: \
+    case 222: \
+    case 223: \
     case 224: \
     case 225: \
     case 226: \
diff --git a/Include/internal/pycore_tuple.h b/Include/internal/pycore_tuple.h
index edde40495021f13..14a9e42c3a324cd 100644
--- a/Include/internal/pycore_tuple.h
+++ b/Include/internal/pycore_tuple.h
@@ -29,8 +29,6 @@ typedef struct {
     PyTupleObject *it_seq; /* Set to NULL when iterator is exhausted */
 } _PyTupleIterObject;
 
-PyAPI_FUNC(int) _PyTuple_Contains(PyTupleObject *a, PyObject *el);
-
 #ifdef __cplusplus
 }
 #endif
diff --git a/Include/internal/pycore_uop_ids.h b/Include/internal/pycore_uop_ids.h
index 5bf10ae6499e690..1209d736abe696f 100644
--- a/Include/internal/pycore_uop_ids.h
+++ b/Include/internal/pycore_uop_ids.h
@@ -76,10 +76,7 @@ extern "C" {
 #define _COMPARE_OP_STR 328
 #define _CONTAINS_OP 329
 #define _CONTAINS_OP_DICT CONTAINS_OP_DICT
-#define _CONTAINS_OP_LIST CONTAINS_OP_LIST
 #define _CONTAINS_OP_SET CONTAINS_OP_SET
-#define _CONTAINS_OP_STR CONTAINS_OP_STR
-#define _CONTAINS_OP_TUPLE CONTAINS_OP_TUPLE
 #define _CONVERT_VALUE CONVERT_VALUE
 #define _COPY COPY
 #define _COPY_FREE_VARS COPY_FREE_VARS
diff --git a/Include/internal/pycore_uop_metadata.h b/Include/internal/pycore_uop_metadata.h
index 23aead27503a7f4..7f984d88299b629 100644
--- a/Include/internal/pycore_uop_metadata.h
+++ b/Include/internal/pycore_uop_metadata.h
@@ -154,11 +154,8 @@ const uint16_t _PyUop_Flags[MAX_UOP_ID+1] = {
     [_COMPARE_OP_STR] = HAS_ARG_FLAG | HAS_ESCAPES_FLAG,
     [_IS_OP] = HAS_ARG_FLAG,
     [_CONTAINS_OP] = HAS_ARG_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
-    [_CONTAINS_OP_LIST] = HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
     [_CONTAINS_OP_SET] = HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
-    [_CONTAINS_OP_TUPLE] = HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
     [_CONTAINS_OP_DICT] = HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
-    [_CONTAINS_OP_STR] = HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
     [_CHECK_EG_MATCH] = HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
     [_CHECK_EXC_MATCH] = HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
     [_IS_NONE] = 0,
@@ -314,10 +311,7 @@ const char *const _PyOpcode_uop_name[MAX_UOP_ID+1] = {
     [_COMPARE_OP_STR] = "_COMPARE_OP_STR",
     [_CONTAINS_OP] = "_CONTAINS_OP",
     [_CONTAINS_OP_DICT] = "_CONTAINS_OP_DICT",
-    [_CONTAINS_OP_LIST] = "_CONTAINS_OP_LIST",
     [_CONTAINS_OP_SET] = "_CONTAINS_OP_SET",
-    [_CONTAINS_OP_STR] = "_CONTAINS_OP_STR",
-    [_CONTAINS_OP_TUPLE] = "_CONTAINS_OP_TUPLE",
     [_CONVERT_VALUE] = "_CONVERT_VALUE",
     [_COPY] = "_COPY",
     [_COPY_FREE_VARS] = "_COPY_FREE_VARS",
diff --git a/Include/opcode_ids.h b/Include/opcode_ids.h
index b76ad8b2bf02914..185205c6870edcc 100644
--- a/Include/opcode_ids.h
+++ b/Include/opcode_ids.h
@@ -164,46 +164,43 @@ extern "C" {
 #define COMPARE_OP_INT                         181
 #define COMPARE_OP_STR                         182
 #define CONTAINS_OP_DICT                       183
-#define CONTAINS_OP_LIST                       184
-#define CONTAINS_OP_SET                        185
-#define CONTAINS_OP_STR                        186
-#define CONTAINS_OP_TUPLE                      187
-#define FOR_ITER_GEN                           188
-#define FOR_ITER_LIST                          189
-#define FOR_ITER_RANGE                         190
-#define FOR_ITER_TUPLE                         191
-#define LOAD_ATTR_CLASS                        192
-#define LOAD_ATTR_GETATTRIBUTE_OVERRIDDEN      193
-#define LOAD_ATTR_INSTANCE_VALUE               194
-#define LOAD_ATTR_METHOD_LAZY_DICT             195
-#define LOAD_ATTR_METHOD_NO_DICT               196
-#define LOAD_ATTR_METHOD_WITH_VALUES           197
-#define LOAD_ATTR_MODULE                       198
-#define LOAD_ATTR_NONDESCRIPTOR_NO_DICT        199
-#define LOAD_ATTR_NONDESCRIPTOR_WITH_VALUES    200
-#define LOAD_ATTR_PROPERTY                     201
-#define LOAD_ATTR_SLOT                         202
-#define LOAD_ATTR_WITH_HINT                    203
-#define LOAD_GLOBAL_BUILTIN                    204
-#define LOAD_GLOBAL_MODULE                     205
-#define LOAD_SUPER_ATTR_ATTR                   206
-#define LOAD_SUPER_ATTR_METHOD                 207
-#define RESUME_CHECK                           208
-#define SEND_GEN                               209
-#define STORE_ATTR_INSTANCE_VALUE              210
-#define STORE_ATTR_SLOT                        211
-#define STORE_ATTR_WITH_HINT                   212
-#define STORE_SUBSCR_DICT                      213
-#define STORE_SUBSCR_LIST_INT                  214
-#define TO_BOOL_ALWAYS_TRUE                    215
-#define TO_BOOL_BOOL                           216
-#define TO_BOOL_INT                            217
-#define TO_BOOL_LIST                           218
-#define TO_BOOL_NONE                           219
-#define TO_BOOL_STR                            220
-#define UNPACK_SEQUENCE_LIST                   221
-#define UNPACK_SEQUENCE_TUPLE                  222
-#define UNPACK_SEQUENCE_TWO_TUPLE              223
+#define CONTAINS_OP_SET                        184
+#define FOR_ITER_GEN                           185
+#define FOR_ITER_LIST                          186
+#define FOR_ITER_RANGE                         187
+#define FOR_ITER_TUPLE                         188
+#define LOAD_ATTR_CLASS                        189
+#define LOAD_ATTR_GETATTRIBUTE_OVERRIDDEN      190
+#define LOAD_ATTR_INSTANCE_VALUE               191
+#define LOAD_ATTR_METHOD_LAZY_DICT             192
+#define LOAD_ATTR_METHOD_NO_DICT               193
+#define LOAD_ATTR_METHOD_WITH_VALUES           194
+#define LOAD_ATTR_MODULE                       195
+#define LOAD_ATTR_NONDESCRIPTOR_NO_DICT        196
+#define LOAD_ATTR_NONDESCRIPTOR_WITH_VALUES    197
+#define LOAD_ATTR_PROPERTY                     198
+#define LOAD_ATTR_SLOT                         199
+#define LOAD_ATTR_WITH_HINT                    200
+#define LOAD_GLOBAL_BUILTIN                    201
+#define LOAD_GLOBAL_MODULE                     202
+#define LOAD_SUPER_ATTR_ATTR                   203
+#define LOAD_SUPER_ATTR_METHOD                 204
+#define RESUME_CHECK                           205
+#define SEND_GEN                               206
+#define STORE_ATTR_INSTANCE_VALUE              207
+#define STORE_ATTR_SLOT                        208
+#define STORE_ATTR_WITH_HINT                   209
+#define STORE_SUBSCR_DICT                      210
+#define STORE_SUBSCR_LIST_INT                  211
+#define TO_BOOL_ALWAYS_TRUE                    212
+#define TO_BOOL_BOOL                           213
+#define TO_BOOL_INT                            214
+#define TO_BOOL_LIST                           215
+#define TO_BOOL_NONE                           216
+#define TO_BOOL_STR                            217
+#define UNPACK_SEQUENCE_LIST                   218
+#define UNPACK_SEQUENCE_TUPLE                  219
+#define UNPACK_SEQUENCE_TWO_TUPLE              220
 #define INSTRUMENTED_RESUME                    236
 #define INSTRUMENTED_END_FOR                   237
 #define INSTRUMENTED_END_SEND                  238
diff --git a/Lib/_opcode_metadata.py b/Lib/_opcode_metadata.py
index 90dfaea46ca0d6c..b5bafe6302bc9ea 100644
--- a/Lib/_opcode_metadata.py
+++ b/Lib/_opcode_metadata.py
@@ -76,11 +76,8 @@
         "COMPARE_OP_STR",
     ],
     "CONTAINS_OP": [
-        "CONTAINS_OP_LIST",
         "CONTAINS_OP_SET",
-        "CONTAINS_OP_TUPLE",
         "CONTAINS_OP_DICT",
-        "CONTAINS_OP_STR",
     ],
     "FOR_ITER": [
         "FOR_ITER_LIST",
@@ -146,46 +143,43 @@
     'COMPARE_OP_INT': 181,
     'COMPARE_OP_STR': 182,
     'CONTAINS_OP_DICT': 183,
-    'CONTAINS_OP_LIST': 184,
-    'CONTAINS_OP_SET': 185,
-    'CONTAINS_OP_STR': 186,
-    'CONTAINS_OP_TUPLE': 187,
-    'FOR_ITER_GEN': 188,
-    'FOR_ITER_LIST': 189,
-    'FOR_ITER_RANGE': 190,
-    'FOR_ITER_TUPLE': 191,
-    'LOAD_ATTR_CLASS': 192,
-    'LOAD_ATTR_GETATTRIBUTE_OVERRIDDEN': 193,
-    'LOAD_ATTR_INSTANCE_VALUE': 194,
-    'LOAD_ATTR_METHOD_LAZY_DICT': 195,
-    'LOAD_ATTR_METHOD_NO_DICT': 196,
-    'LOAD_ATTR_METHOD_WITH_VALUES': 197,
-    'LOAD_ATTR_MODULE': 198,
-    'LOAD_ATTR_NONDESCRIPTOR_NO_DICT': 199,
-    'LOAD_ATTR_NONDESCRIPTOR_WITH_VALUES': 200,
-    'LOAD_ATTR_PROPERTY': 201,
-    'LOAD_ATTR_SLOT': 202,
-    'LOAD_ATTR_WITH_HINT': 203,
-    'LOAD_GLOBAL_BUILTIN': 204,
-    'LOAD_GLOBAL_MODULE': 205,
-    'LOAD_SUPER_ATTR_ATTR': 206,
-    'LOAD_SUPER_ATTR_METHOD': 207,
-    'RESUME_CHECK': 208,
-    'SEND_GEN': 209,
-    'STORE_ATTR_INSTANCE_VALUE': 210,
-    'STORE_ATTR_SLOT': 211,
-    'STORE_ATTR_WITH_HINT': 212,
-    'STORE_SUBSCR_DICT': 213,
-    'STORE_SUBSCR_LIST_INT': 214,
-    'TO_BOOL_ALWAYS_TRUE': 215,
-    'TO_BOOL_BOOL': 216,
-    'TO_BOOL_INT': 217,
-    'TO_BOOL_LIST': 218,
-    'TO_BOOL_NONE': 219,
-    'TO_BOOL_STR': 220,
-    'UNPACK_SEQUENCE_LIST': 221,
-    'UNPACK_SEQUENCE_TUPLE': 222,
-    'UNPACK_SEQUENCE_TWO_TUPLE': 223,
+    'CONTAINS_OP_SET': 184,
+    'FOR_ITER_GEN': 185,
+    'FOR_ITER_LIST': 186,
+    'FOR_ITER_RANGE': 187,
+    'FOR_ITER_TUPLE': 188,
+    'LOAD_ATTR_CLASS': 189,
+    'LOAD_ATTR_GETATTRIBUTE_OVERRIDDEN': 190,
+    'LOAD_ATTR_INSTANCE_VALUE': 191,
+    'LOAD_ATTR_METHOD_LAZY_DICT': 192,
+    'LOAD_ATTR_METHOD_NO_DICT': 193,
+    'LOAD_ATTR_METHOD_WITH_VALUES': 194,
+    'LOAD_ATTR_MODULE': 195,
+    'LOAD_ATTR_NONDESCRIPTOR_NO_DICT': 196,
+    'LOAD_ATTR_NONDESCRIPTOR_WITH_VALUES': 197,
+    'LOAD_ATTR_PROPERTY': 198,
+    'LOAD_ATTR_SLOT': 199,
+    'LOAD_ATTR_WITH_HINT': 200,
+    'LOAD_GLOBAL_BUILTIN': 201,
+    'LOAD_GLOBAL_MODULE': 202,
+    'LOAD_SUPER_ATTR_ATTR': 203,
+    'LOAD_SUPER_ATTR_METHOD': 204,
+    'RESUME_CHECK': 205,
+    'SEND_GEN': 206,
+    'STORE_ATTR_INSTANCE_VALUE': 207,
+    'STORE_ATTR_SLOT': 208,
+    'STORE_ATTR_WITH_HINT': 209,
+    'STORE_SUBSCR_DICT': 210,
+    'STORE_SUBSCR_LIST_INT': 211,
+    'TO_BOOL_ALWAYS_TRUE': 212,
+    'TO_BOOL_BOOL': 213,
+    'TO_BOOL_INT': 214,
+    'TO_BOOL_LIST': 215,
+    'TO_BOOL_NONE': 216,
+    'TO_BOOL_STR': 217,
+    'UNPACK_SEQUENCE_LIST': 218,
+    'UNPACK_SEQUENCE_TUPLE': 219,
+    'UNPACK_SEQUENCE_TWO_TUPLE': 220,
 }
 
 opmap = {
diff --git a/Objects/listobject.c b/Objects/listobject.c
index db8eedf18c556ef..e013383a712bc81 100644
--- a/Objects/listobject.c
+++ b/Objects/listobject.c
@@ -524,8 +524,8 @@ list_length(PyObject *a)
     return PyList_GET_SIZE(a);
 }
 
-int
-_PyList_Contains(PyObject *aa, PyObject *el)
+static int
+list_contains(PyObject *aa, PyObject *el)
 {
 
     for (Py_ssize_t i = 0; ; i++) {
@@ -3147,7 +3147,7 @@ static PySequenceMethods list_as_sequence = {
     0,                                          /* sq_slice */
     list_ass_item,                              /* sq_ass_item */
     0,                                          /* sq_ass_slice */
-    _PyList_Contains,                           /* sq_contains */
+    list_contains,                              /* sq_contains */
     list_inplace_concat,                        /* sq_inplace_concat */
     list_inplace_repeat,                        /* sq_inplace_repeat */
 };
diff --git a/Objects/tupleobject.c b/Objects/tupleobject.c
index 5bbc0279c21d8d3..d9dc00da368a84c 100644
--- a/Objects/tupleobject.c
+++ b/Objects/tupleobject.c
@@ -349,8 +349,8 @@ tuplelength(PyTupleObject *a)
     return Py_SIZE(a);
 }
 
-int
-_PyTuple_Contains(PyTupleObject *a, PyObject *el)
+static int
+tuplecontains(PyTupleObject *a, PyObject *el)
 {
     Py_ssize_t i;
     int cmp;
@@ -758,7 +758,7 @@ static PySequenceMethods tuple_as_sequence = {
     0,                                          /* sq_slice */
     0,                                          /* sq_ass_item */
     0,                                          /* sq_ass_slice */
-    (objobjproc)_PyTuple_Contains,              /* sq_contains */
+    (objobjproc)tuplecontains,                  /* sq_contains */
 };
 
 static PyObject*
diff --git a/Python/bytecodes.c b/Python/bytecodes.c
index 3276a4a9644b8f6..0397d96e3f63ba9 100644
--- a/Python/bytecodes.c
+++ b/Python/bytecodes.c
@@ -2238,11 +2238,8 @@ dummy_func(
         }
 
         family(CONTAINS_OP, INLINE_CACHE_ENTRIES_CONTAINS_OP) = {
-            CONTAINS_OP_LIST,
             CONTAINS_OP_SET,
-            CONTAINS_OP_TUPLE,
             CONTAINS_OP_DICT,
-            CONTAINS_OP_STR,
         };
 
         op(_CONTAINS_OP, (left, right -- b)) {
@@ -2266,46 +2263,25 @@ dummy_func(
 
         macro(CONTAINS_OP) = _SPECIALIZE_CONTAINS_OP + _CONTAINS_OP;
 
-        inst(CONTAINS_OP_LIST, (unused/1, left, right -- b)) {
-            DEOPT_IF(!PyList_CheckExact(right));
-            int res = _PyList_Contains(right, left);
-            DECREF_INPUTS();
-            ERROR_IF(res < 0, error);
-            b = (res ^ oparg) ? Py_True : Py_False;
-        }
-
         inst(CONTAINS_OP_SET, (unused/1, left, right -- b)) {
-            DEOPT_IF(!PySet_CheckExact(right));
+            DEOPT_IF(!(PySet_CheckExact(right) || PyFrozenSet_CheckExact(right)));
+            STAT_INC(CONTAINS_OP, hit);
+            // Note: both set and frozenset use the same seq_contains method!
             int res = _PySet_Contains((PySetObject *)right, left);
             DECREF_INPUTS();
             ERROR_IF(res < 0, error);
             b = (res ^ oparg) ? Py_True : Py_False;
         }
 
-        inst(CONTAINS_OP_TUPLE, (unused/1, left, right -- b)) {
-            DEOPT_IF(!PyTuple_CheckExact(right));
-            int res = _PyTuple_Contains((PyTupleObject *)right, left);
-            DECREF_INPUTS();
-            ERROR_IF(res < 0, error);
-            b = (res ^ oparg) ? Py_True : Py_False;
-        }
-
         inst(CONTAINS_OP_DICT, (unused/1, left, right -- b)) {
             DEOPT_IF(!PyDict_CheckExact(right));
+            STAT_INC(CONTAINS_OP, hit);
             int res = PyDict_Contains(right, left);
             DECREF_INPUTS();
             ERROR_IF(res < 0, error);
             b = (res ^ oparg) ? Py_True : Py_False;
         }
 
-        inst(CONTAINS_OP_STR, (unused/1, left, right -- b)) {
-            DEOPT_IF(!PyUnicode_CheckExact(right));
-            int res = PyUnicode_Contains(right, left);
-            DECREF_INPUTS();
-            ERROR_IF(res < 0, error);
-            b = (res ^ oparg) ? Py_True : Py_False;
-        }
-
         inst(CHECK_EG_MATCH, (exc_value, match_type -- rest, match)) {
             if (_PyEval_CheckExceptStarTypeValid(tstate, match_type) < 0) {
                 DECREF_INPUTS();
diff --git a/Python/executor_cases.c.h b/Python/executor_cases.c.h
index 2e7b970b4ddb9e2..26ac1593d534e47 100644
--- a/Python/executor_cases.c.h
+++ b/Python/executor_cases.c.h
@@ -2189,24 +2189,6 @@
             break;
         }
 
-        case _CONTAINS_OP_LIST: {
-            PyObject *right;
-            PyObject *left;
-            PyObject *b;
-            oparg = CURRENT_OPARG();
-            right = stack_pointer[-1];
-            left = stack_pointer[-2];
-            if (!PyList_CheckExact(right)) goto deoptimize;
-            int res = _PyList_Contains(right, left);
-            Py_DECREF(left);
-            Py_DECREF(right);
-            if (res < 0) goto pop_2_error_tier_two;
-            b = (res ^ oparg) ? Py_True : Py_False;
-            stack_pointer[-2] = b;
-            stack_pointer += -1;
-            break;
-        }
-
         case _CONTAINS_OP_SET: {
             PyObject *right;
             PyObject *left;
@@ -2214,7 +2196,9 @@
             oparg = CURRENT_OPARG();
             right = stack_pointer[-1];
             left = stack_pointer[-2];
-            if (!PySet_CheckExact(right)) goto deoptimize;
+            if (!(PySet_CheckExact(right) || PyFrozenSet_CheckExact(right))) goto deoptimize;
+            STAT_INC(CONTAINS_OP, hit);
+            // Note: both set and frozenset use the same seq_contains method!
             int res = _PySet_Contains((PySetObject *)right, left);
             Py_DECREF(left);
             Py_DECREF(right);
@@ -2225,24 +2209,6 @@
             break;
         }
 
-        case _CONTAINS_OP_TUPLE: {
-            PyObject *right;
-            PyObject *left;
-            PyObject *b;
-            oparg = CURRENT_OPARG();
-            right = stack_pointer[-1];
-            left = stack_pointer[-2];
-            if (!PyTuple_CheckExact(right)) goto deoptimize;
-            int res = _PyTuple_Contains((PyTupleObject *)right, left);
-            Py_DECREF(left);
-            Py_DECREF(right);
-            if (res < 0) goto pop_2_error_tier_two;
-            b = (res ^ oparg) ? Py_True : Py_False;
-            stack_pointer[-2] = b;
-            stack_pointer += -1;
-            break;
-        }
-
         case _CONTAINS_OP_DICT: {
             PyObject *right;
             PyObject *left;
@@ -2251,6 +2217,7 @@
             right = stack_pointer[-1];
             left = stack_pointer[-2];
             if (!PyDict_CheckExact(right)) goto deoptimize;
+            STAT_INC(CONTAINS_OP, hit);
             int res = PyDict_Contains(right, left);
             Py_DECREF(left);
             Py_DECREF(right);
@@ -2261,24 +2228,6 @@
             break;
         }
 
-        case _CONTAINS_OP_STR: {
-            PyObject *right;
-            PyObject *left;
-            PyObject *b;
-            oparg = CURRENT_OPARG();
-            right = stack_pointer[-1];
-            left = stack_pointer[-2];
-            if (!PyUnicode_CheckExact(right)) goto deoptimize;
-            int res = PyUnicode_Contains(right, left);
-            Py_DECREF(left);
-            Py_DECREF(right);
-            if (res < 0) goto pop_2_error_tier_two;
-            b = (res ^ oparg) ? Py_True : Py_False;
-            stack_pointer[-2] = b;
-            stack_pointer += -1;
-            break;
-        }
-
         case _CHECK_EG_MATCH: {
             PyObject *match_type;
             PyObject *exc_value;
diff --git a/Python/generated_cases.c.h b/Python/generated_cases.c.h
index 54c48617fd4df53..f5d125c63b10ca4 100644
--- a/Python/generated_cases.c.h
+++ b/Python/generated_cases.c.h
@@ -2176,6 +2176,7 @@
             right = stack_pointer[-1];
             left = stack_pointer[-2];
             DEOPT_IF(!PyDict_CheckExact(right), CONTAINS_OP);
+            STAT_INC(CONTAINS_OP, hit);
             int res = PyDict_Contains(right, left);
             Py_DECREF(left);
             Py_DECREF(right);
@@ -2186,28 +2187,6 @@
             DISPATCH();
         }
 
-        TARGET(CONTAINS_OP_LIST) {
-            frame->instr_ptr = next_instr;
-            next_instr += 2;
-            INSTRUCTION_STATS(CONTAINS_OP_LIST);
-            static_assert(INLINE_CACHE_ENTRIES_CONTAINS_OP == 1, "incorrect cache size");
-            PyObject *right;
-            PyObject *left;
-            PyObject *b;
-            /* Skip 1 cache entry */
-            right = stack_pointer[-1];
-            left = stack_pointer[-2];
-            DEOPT_IF(!PyList_CheckExact(right), CONTAINS_OP);
-            int res = _PyList_Contains(right, left);
-            Py_DECREF(left);
-            Py_DECREF(right);
-            if (res < 0) goto pop_2_error;
-            b = (res ^ oparg) ? Py_True : Py_False;
-            stack_pointer[-2] = b;
-            stack_pointer += -1;
-            DISPATCH();
-        }
-
         TARGET(CONTAINS_OP_SET) {
             frame->instr_ptr = next_instr;
             next_instr += 2;
@@ -2219,7 +2198,9 @@
             /* Skip 1 cache entry */
             right = stack_pointer[-1];
             left = stack_pointer[-2];
-            DEOPT_IF(!PySet_CheckExact(right), CONTAINS_OP);
+            DEOPT_IF(!(PySet_CheckExact(right) || PyFrozenSet_CheckExact(right)), CONTAINS_OP);
+            STAT_INC(CONTAINS_OP, hit);
+            // Note: both set and frozenset use the same seq_contains method!
             int res = _PySet_Contains((PySetObject *)right, left);
             Py_DECREF(left);
             Py_DECREF(right);
@@ -2230,50 +2211,6 @@
             DISPATCH();
         }
 
-        TARGET(CONTAINS_OP_STR) {
-            frame->instr_ptr = next_instr;
-            next_instr += 2;
-            INSTRUCTION_STATS(CONTAINS_OP_STR);
-            static_assert(INLINE_CACHE_ENTRIES_CONTAINS_OP == 1, "incorrect cache size");
-            PyObject *right;
-            PyObject *left;
-            PyObject *b;
-            /* Skip 1 cache entry */
-            right = stack_pointer[-1];
-            left = stack_pointer[-2];
-            DEOPT_IF(!PyUnicode_CheckExact(right), CONTAINS_OP);
-            int res = PyUnicode_Contains(right, left);
-            Py_DECREF(left);
-            Py_DECREF(right);
-            if (res < 0) goto pop_2_error;
-            b = (res ^ oparg) ? Py_True : Py_False;
-            stack_pointer[-2] = b;
-            stack_pointer += -1;
-            DISPATCH();
-        }
-
-        TARGET(CONTAINS_OP_TUPLE) {
-            frame->instr_ptr = next_instr;
-            next_instr += 2;
-            INSTRUCTION_STATS(CONTAINS_OP_TUPLE);
-            static_assert(INLINE_CACHE_ENTRIES_CONTAINS_OP == 1, "incorrect cache size");
-            PyObject *right;
-            PyObject *left;
-            PyObject *b;
-            /* Skip 1 cache entry */
-            right = stack_pointer[-1];
-            left = stack_pointer[-2];
-            DEOPT_IF(!PyTuple_CheckExact(right), CONTAINS_OP);
-            int res = _PyTuple_Contains((PyTupleObject *)right, left);
-            Py_DECREF(left);
-            Py_DECREF(right);
-            if (res < 0) goto pop_2_error;
-            b = (res ^ oparg) ? Py_True : Py_False;
-            stack_pointer[-2] = b;
-            stack_pointer += -1;
-            DISPATCH();
-        }
-
         TARGET(CONVERT_VALUE) {
             frame->instr_ptr = next_instr;
             next_instr += 1;
diff --git a/Python/opcode_targets.h b/Python/opcode_targets.h
index 6b3846d46296ad2..4061ba33cea53ea 100644
--- a/Python/opcode_targets.h
+++ b/Python/opcode_targets.h
@@ -183,10 +183,7 @@ static void *opcode_targets[256] = {
     &&TARGET_COMPARE_OP_INT,
     &&TARGET_COMPARE_OP_STR,
     &&TARGET_CONTAINS_OP_DICT,
-    &&TARGET_CONTAINS_OP_LIST,
     &&TARGET_CONTAINS_OP_SET,
-    &&TARGET_CONTAINS_OP_STR,
-    &&TARGET_CONTAINS_OP_TUPLE,
     &&TARGET_FOR_ITER_GEN,
     &&TARGET_FOR_ITER_LIST,
     &&TARGET_FOR_ITER_RANGE,
@@ -235,6 +232,9 @@ static void *opcode_targets[256] = {
     &&_unknown_opcode,
     &&_unknown_opcode,
     &&_unknown_opcode,
+    &&_unknown_opcode,
+    &&_unknown_opcode,
+    &&_unknown_opcode,
     &&TARGET_INSTRUMENTED_RESUME,
     &&TARGET_INSTRUMENTED_END_FOR,
     &&TARGET_INSTRUMENTED_END_SEND,
diff --git a/Python/optimizer_cases.c.h b/Python/optimizer_cases.c.h
index e4384975643ecd3..c88b25132c0e902 100644
--- a/Python/optimizer_cases.c.h
+++ b/Python/optimizer_cases.c.h
@@ -1218,15 +1218,6 @@
             break;
         }
 
-        case _CONTAINS_OP_LIST: {
-            _Py_UopsSymbol *b;
-            b = sym_new_unknown(ctx);
-            if (b == NULL) goto out_of_space;
-            stack_pointer[-2] = b;
-            stack_pointer += -1;
-            break;
-        }
-
         case _CONTAINS_OP_SET: {
             _Py_UopsSymbol *b;
             b = sym_new_unknown(ctx);
@@ -1236,15 +1227,6 @@
             break;
         }
 
-        case _CONTAINS_OP_TUPLE: {
-            _Py_UopsSymbol *b;
-            b = sym_new_unknown(ctx);
-            if (b == NULL) goto out_of_space;
-            stack_pointer[-2] = b;
-            stack_pointer += -1;
-            break;
-        }
-
         case _CONTAINS_OP_DICT: {
             _Py_UopsSymbol *b;
             b = sym_new_unknown(ctx);
@@ -1254,15 +1236,6 @@
             break;
         }
 
-        case _CONTAINS_OP_STR: {
-            _Py_UopsSymbol *b;
-            b = sym_new_unknown(ctx);
-            if (b == NULL) goto out_of_space;
-            stack_pointer[-2] = b;
-            stack_pointer += -1;
-            break;
-        }
-
         case _CHECK_EG_MATCH: {
             _Py_UopsSymbol *rest;
             _Py_UopsSymbol *match;
diff --git a/Python/specialize.c b/Python/specialize.c
index 5d339b8a476cf50..b1f9eb756c36653 100644
--- a/Python/specialize.c
+++ b/Python/specialize.c
@@ -600,6 +600,12 @@ _PyCode_Quicken(PyCodeObject *code)
 #define SPEC_FAIL_TO_BOOL_SET         17
 #define SPEC_FAIL_TO_BOOL_TUPLE       18
 
+// CONTAINS_OP
+#define SPEC_FAIL_CONTAINS_OP_STR        9
+#define SPEC_FAIL_CONTAINS_OP_TUPLE      10
+#define SPEC_FAIL_CONTAINS_OP_LIST       11
+#define SPEC_FAIL_CONTAINS_OP_USER_CLASS 12
+
 static int function_kind(PyCodeObject *code);
 static bool function_check_args(PyObject *o, int expected_argcount, int opcode);
 static uint32_t function_get_version(PyObject *o, int opcode);
@@ -2562,34 +2568,40 @@ _Py_Specialize_ToBool(PyObject *value, _Py_CODEUNIT *instr)
     cache->counter = adaptive_counter_cooldown();
 }
 
-void
-_Py_Specialize_ContainsOp(PyObject *value, _Py_CODEUNIT *instr)
-{
-    assert(ENABLE_SPECIALIZATION);
-    assert(_PyOpcode_Caches[CONTAINS_OP] == INLINE_CACHE_ENTRIES_COMPARE_OP);
-    _PyContainsOpCache *cache = (_PyContainsOpCache  *)(instr + 1);
+#ifdef Py_STATS
+static int containsop_fail_kind(PyObject *value) {
     if (PyUnicode_CheckExact(value)) {
-        instr->op.code = CONTAINS_OP_STR;
-        goto success;
+        return SPEC_FAIL_CONTAINS_OP_STR;
     }
     if (PyList_CheckExact(value)) {
-        instr->op.code = CONTAINS_OP_LIST;
-        goto success;
+        return SPEC_FAIL_CONTAINS_OP_LIST;
     }
     if (PyTuple_CheckExact(value)) {
-        instr->op.code = CONTAINS_OP_TUPLE;
-        goto success;
+        return SPEC_FAIL_CONTAINS_OP_TUPLE;
+    }
+    if (PyType_Check(value)) {
+        return SPEC_FAIL_CONTAINS_OP_USER_CLASS;
     }
+    return SPEC_FAIL_OTHER;
+}
+#endif   // Py_STATS
+
+void
+_Py_Specialize_ContainsOp(PyObject *value, _Py_CODEUNIT *instr)
+{
+    assert(ENABLE_SPECIALIZATION);
+    assert(_PyOpcode_Caches[CONTAINS_OP] == INLINE_CACHE_ENTRIES_COMPARE_OP);
+    _PyContainsOpCache *cache = (_PyContainsOpCache  *)(instr + 1);
     if (PyDict_CheckExact(value)) {
         instr->op.code = CONTAINS_OP_DICT;
         goto success;
     }
-    if (PySet_CheckExact(value)) {
+    if (PySet_CheckExact(value) || PyFrozenSet_CheckExact(value)) {
         instr->op.code = CONTAINS_OP_SET;
         goto success;
     }
 
-
+    SPECIALIZATION_FAIL(CONTAINS_OP, containsop_fail_kind(value));
     STAT_INC(CONTAINS_OP, failure);
     instr->op.code = CONTAINS_OP;
     cache->counter = adaptive_counter_backoff(cache->counter);
diff --git a/Tools/jit/template.c b/Tools/jit/template.c
index 8aaf4581de362d3..504e6c875525ae9 100644
--- a/Tools/jit/template.c
+++ b/Tools/jit/template.c
@@ -13,6 +13,7 @@
 #include "pycore_range.h"
 #include "pycore_setobject.h"
 #include "pycore_sliceobject.h"
+#include "pycore_descrobject.h"
 
 #include "ceval_macros.h"