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Allow multiple covariates #67

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drisso opened this issue Sep 2, 2016 · 3 comments
Open

Allow multiple covariates #67

drisso opened this issue Sep 2, 2016 · 3 comments
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enhancement

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@drisso
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drisso commented Sep 2, 2016

The user should be able to adjust for other (categorical and continuous) covariates in addition to batch.
@allonw
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allonw commented Sep 2, 2016

I assume that this means allowing any design matrix of technical covariates (maybe with some convenience functions for common cases)? If so, it should be allowed also for the bio covariates.

@drisso
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drisso commented Sep 2, 2016

Yes. It should allow an arbitrary number of covariates to be removed and an arbitrary number of covariates to be preserved.

@drisso
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drisso commented Nov 1, 2016

The plan is to add a single covariate for the moment. To do this:

  • Add the adjust_covariate=c("no", "yes", "force") argument
  • Modify parse_row() and make_design()
  • Modify scone()

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@drisso @allonw