diff --git a/lib/class-wp-rest-image-editor-controller.php b/lib/class-wp-rest-image-editor-controller.php
index cdb05b498f98fa..ebf3ea1b916c9c 100644
--- a/lib/class-wp-rest-image-editor-controller.php
+++ b/lib/class-wp-rest-image-editor-controller.php
@@ -147,7 +147,15 @@ public function apply_edits( $request ) {
 			return new WP_Error( 'rest_image_not_edited', $error, array( 'status' => 400 ) );
 		}
 
-		$image_editor = wp_get_image_editor( $image_file );
+		// If the file doesn't exist, attempt a URL fopen on the src link.
+		// This can occur with certain file replication plugins.
+		// Keep the original file path to get a modified name later.
+		$image_file_to_edit = $image_file;
+		if ( ! file_exists( $image_file_to_edit ) ) {
+			$image_file_to_edit = _load_image_to_edit_path( $attachment_id );
+		}
+
+		$image_editor = wp_get_image_editor( $image_file_to_edit );
 
 		if ( is_wp_error( $image_editor ) ) {
 			// This image cannot be edited.