diff --git a/combos.json b/combos.json index 2015723..dabdf18 100644 --- a/combos.json +++ b/combos.json @@ -267,7 +267,7 @@ "status": "Caution" }, "cocaine": { - "note": "The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics. ", + "note": "The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics.", "status": "Unsafe" }, "dextromethorphan": { @@ -1537,7 +1537,7 @@ "status": "Low Risk & Decrease" }, "ketamine": { - "note": "Ketamine and psychedelics tend to potentiate each other - go slowly.", + "note": "Ketamine and psychedelics tend to potentiate each other and it is be cautious when mixing. Starting with lower dosages is ideal.", "status": "Low Risk & Synergy" }, "lithium": { @@ -2414,7 +2414,7 @@ "status": "Low Risk & Synergy" }, "ketamine": { - "note": "MAO-B inhibitors appear to increase the potency of ketamine. MAO-A inhbitors have some negative reports associated with the combination but there isn't much information available", + "note": "MAO-B inhibitors appear to increase the potency of Ketamine. MAO-A inhbitors have some negative reports associated with the combination but there isn't much information available", "status": "Caution" }, "lsd": { @@ -3053,7 +3053,7 @@ "status": "Low Risk & Decrease" }, "caffeine": { - "note": "Caffiene can bring out the natural stimulation from psychedelic drugs to make it uncomfortable. High doses can cause anxiety which can be hard to handle while tripping", + "note": "Caffiene can bring out the natural stimulation from psychedelic drugs to make it uncomfortable. High doses can cause anxiety which is hard to handle while tripping", "status": "Caution" }, "cannabis": { @@ -3288,7 +3288,7 @@ "status": "Low Risk & Synergy" }, "cocaine": { - "note": "Stimulants increase respiration rate allowing for a higher dose of opioids than normal. If the stimulant wears off first then the opioids may overcome the individual and cause respiratory arrest.", + "note": "Stimulants increase respiration rate allowing for a higher dose of opioids than normal. If the stimulant wears off first then the opioid may overcome the individual and cause respiratory arrest.", "status": "Dangerous" }, "dextromethorphan": { @@ -3453,7 +3453,7 @@ "status": "Low Risk & Decrease" }, "alcohol": { - "note": "Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.", + "note": "Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.", "status": "Caution" }, "amphetamines": { @@ -3476,7 +3476,7 @@ "status": "Low Risk & No Synergy" }, "dextromethorphan": { - "note": "At recreational dosages, there is a high risk of serotonin syndrome.", + "note": "High risk of serotonin syndrome.", "status": "Dangerous" }, "dmt": { @@ -3583,7 +3583,7 @@ "status": "Unsafe" }, "alcohol": { - "note": "Both drugs are heavy CNS depressants, and there is a risk of seizures with this combination. Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place the affected individual in the recovery position to prevent vomit aspiration from excess. Memory blackouts are likely.", + "note": "Heavy CNS depressants, risk of seizures. Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place the affected individual in the recovery position to prevent vomit aspiration from excess. Memory blackouts are likely.", "status": "Dangerous" }, "amphetamines": { @@ -3678,7 +3678,7 @@ "status": "Dangerous" }, "mescaline": { - "note": "This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures.", + "note": "This combination can cause seizures due to the lowering of the seizure threshold by Tramadol and the potential of mescaline to cause seziures.", "status": "Unsafe" }, "mushrooms": { diff --git a/drugs.json b/drugs.json index 5ebee9e..d2f20de 100644 --- a/drugs.json +++ b/drugs.json @@ -10964,7 +10964,7 @@ "status": "Caution" }, "benzodiazepines": { - "note": "Ethanol ingestion may potentiate the CNS effects of many benzodiazepines. The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Blacking out and memory loss is almost certain.", + "note": "Ethanol ingestion may potentiate the CNS effects of many benzodiazepines. The two substances potentiate each other strongly and unpredictably, often leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position.. Blacking out and memory loss is almost certain.", "status": "Dangerous" }, "caffeine": { @@ -14133,7 +14133,7 @@ "status": "Low Risk & Synergy" }, "mdma": { - "note": "Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. Cannabis should be saved for towards the end of the experience if possible.", + "note": "Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. It may be suggested to consume cannabis later on in the MDMA once the peak MDMA effects have passed.", "status": "Low Risk & Synergy" }, "mescaline": { @@ -15265,7 +15265,7 @@ "status": "Caution" }, "5-meo-xxt": { - "note": "The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics. ", + "note": "The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics.", "status": "Unsafe" }, "alcohol": { @@ -15325,7 +15325,7 @@ "status": "Unsafe" }, "ghb/gbl": { - "note": "Stimulants increase respiration rate allowing for a higher dose of sedatives than normal. If the stimulant wears off first the opiate may overcome the individual and cause respiratory arrest. Likewise the ghb/gbl can wear off and leave a dangerous concentration of cocaine behind", + "note": "Stimulants increase respiration rate allowing for a higher dose of sedatives than normal. If the stimulant wears off first the opioid may overcome the individual and cause respiratory arrest. Likewise the ghb/gbl can wear off and leave a dangerous concentration of cocaine behind", "status": "Caution" }, "ketamine": { @@ -15380,11 +15380,11 @@ "status": "Low Risk & Synergy" }, "opioids": { - "note": "Stimulants increase respiration rate allowing for a higher dose of opiates than normal. If the stimulant wears off first then the opiate may overcome the individual and cause respiratory arrest.", + "note": "Stimulants increase respiration rate allowing for a higher dose of opioids than normal. If the stimulant wears off first then the opioid may overcome the individual and cause respiratory arrest.", "status": "Dangerous" }, "pcp": { - "note": "This combination can easily lead to hypermanic states", + "note": "This combination may lead to hypermanic states", "status": "Unsafe" }, "ssris": { @@ -16822,7 +16822,7 @@ "status": "Low Risk & Synergy" }, "dox": { - "note": "The DOx class as psychedelic stimulants have the potential to mask the effects of DXM and could lead to redosing to an unsafe level. DXM can also potentiate DOx resulting in an unpleasantly intense experience.", + "note": "The DOx class as psychedelic stimulants have the potential to mask the effects of dextromethorphan and could lead to redosing to an unsafe level. dextromethorphan can also potentiate DOx resulting in an unpleasantly intense experience.", "status": "Unsafe" }, "ghb/gbl": { @@ -16923,7 +16923,7 @@ "status": "Low Risk & Synergy" }, "mxe": { - "note": "There is a risk of serotonin syndrome when combining DXM with MXE, due to DXM and MXE both being SRI’s. MXE and DXM having notable affinities for the serotonin transporter.", + "note": "There is a risk of serotonin syndrome when combining dextromethorphan with MXE, due to dextromethorphan and MXE both being SRI’s. MXE and dextromethorphan having notable affinities for the serotonin transporter.", "sources": [ { "author": "Bryan L. Roth, Simon Gibbons, Warunya Arunotayanun, Xi-Ping Huang, Vincent Setola, Ric Treble, Les Iversen", @@ -16960,7 +16960,7 @@ "status": "Low Risk & Synergy" }, "opioids": { - "note": "CNS depression, difficult breathing, heart issues, hepatoxic, just very unsafe combination all around. Additionally if one takes DXM, their tolerance of opiates goes down slightly, thus causing additional synergistic effects.", + "note": "CNS depression, difficult breathing, heart issues, hepatoxic, just very unsafe combination all around. Additionally if one takes dextromethorphan, their tolerance of opioids goes down slightly, thus causing additional synergistic effects.", "status": "Dangerous" }, "pcp": { @@ -22801,7 +22801,7 @@ "status": "Low Risk & Synergy" }, "dox": { - "note": "Ketamine and psychedelics tend to potentiate each other - go slowly.", + "note": "Ketamine and psychedelics tend to potentiate each other and it is be cautious when mixing. Starting with lower dosages is ideal.", "status": "Low Risk & Synergy" }, "ghb/gbl": { @@ -22835,7 +22835,7 @@ "status": "Low Risk & Synergy" }, "opioids": { - "note": "Both substances bring a risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position.", + "note": "The two substances potentiate each other strongly and unpredictably, often leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position.", "status": "Dangerous" }, "pcp": { @@ -24786,7 +24786,7 @@ "status": "Caution" }, "cannabis": { - "note": "Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. Cannabis should be saved for towards the end of the experience if possible.", + "note": "Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. It may be suggested to consume cannabis later on in the MDMA once the peak MDMA effects have passed.", "status": "Low Risk & Synergy" }, "cocaine": { @@ -24800,7 +24800,7 @@ "status": "Low Risk & Synergy" }, "dox": { - "note": "The combined stimulating effects of the two can be uncomfortable. Coming down on the MDMA while the DOx is still active can be quite anxiogenic. ", + "note": "The combined stimulating effects of the two can be uncomfortable. Coming down on the MDMA while the DOx is still active can be quite anxiogenic.", "status": "Caution" }, "ghb/gbl": { @@ -24864,7 +24864,7 @@ "status": "Low Risk & No Synergy" }, "pcp": { - "note": "This combination can easily lead to hypermanic states", + "note": "This combination may lead to hypermanic states", "status": "Unsafe" }, "ssris": { @@ -25941,7 +25941,7 @@ "status": "Low Risk & Decrease" }, "tramadol": { - "note": "This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures.", + "note": "This combination can cause seizures due to the lowering of the seizure threshold by Tramadol and the potential of mescaline to cause seziures.", "status": "Unsafe" } }, @@ -28345,7 +28345,7 @@ "status": "Caution" }, "dextromethorphan": { - "note": "There is a risk of serotonin syndrome when combining DXM with MXE, due to DXM and MXE both being SRI’s. MXE and DXM having notable affinities for the serotonin transporter.", + "note": "There is a risk of serotonin syndrome when combining dextromethorphan with MXE, due to dextromethorphan and MXE both being SRI’s. MXE and dextromethorphan having notable affinities for the serotonin transporter.", "sources": [ { "author": "Bryan L. Roth, Simon Gibbons, Warunya Arunotayanun, Xi-Ping Huang, Vincent Setola, Ric Treble, Les Iversen", @@ -30443,7 +30443,7 @@ "status": "Unsafe" }, "amphetamines": { - "note": "This combination can easily lead to hypermanic states", + "note": "This combination may lead to hypermanic states", "status": "Unsafe" }, "amt": { @@ -30461,7 +30461,7 @@ "status": "Low Risk & Synergy" }, "cocaine": { - "note": "This combination can easily lead to hypermanic states", + "note": "This combination may lead to hypermanic states", "status": "Unsafe" }, "dextromethorphan": { @@ -30489,7 +30489,7 @@ "status": "Dangerous" }, "mdma": { - "note": "This combination can easily lead to hypermanic states", + "note": "This combination may lead to hypermanic states", "status": "Unsafe" }, "mescaline": { @@ -34204,7 +34204,7 @@ "status": "Dangerous" }, "mescaline": { - "note": "This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures.", + "note": "This combination can cause seizures due to the lowering of the seizure threshold by Tramadol and the potential of mescaline to cause seziures.", "status": "Unsafe" }, "mushrooms": {