From 9cdb3e8373fcc2182f6c0f5d9b935cab6d6c262e Mon Sep 17 00:00:00 2001 From: FEIRANL Date: Sun, 26 Aug 2018 00:05:54 +0200 Subject: [PATCH 01/27] feat-data:Biolog experiment Add Biolog experiment data and a code to predict substrate usage --- .../modelCuration/Biolog_Substrate.tsv | 384 ++++++++++++++++++ .../modelCuration/SubstrateUsage.m | 209 ++++++++++ 2 files changed, 593 insertions(+) create mode 100644 ComplementaryData/modelCuration/Biolog_Substrate.tsv create mode 100644 ComplementaryScripts/modelCuration/SubstrateUsage.m diff --git a/ComplementaryData/modelCuration/Biolog_Substrate.tsv b/ComplementaryData/modelCuration/Biolog_Substrate.tsv new file mode 100644 index 00000000..ab60202d --- /dev/null +++ b/ComplementaryData/modelCuration/Biolog_Substrate.tsv @@ -0,0 +1,384 @@ +subtaate Name_In_Model Substrate_type Growth_Biolog Growth_Model +L-Malic Acid (S)-malate C NG NA +L-Glutamic Acid L-glutamate C NG NA +Thymidine thymidine C NG NA +D-Malic Acid C NG NA +L-Alanine L-alanine C NG NA +Fumaric Acid fumarate C NG NA +L-Lactic Acid (S)-lactate C G NA +Butyric Acid butyrate C NG NA +Methyl Pyruvate C NG NA +α-Keto-Glutaric Acid 2-oxoglutarate C NG NA +D,L-Malic Acid C NG NA +L-Alanyl-Glycine Ala-Gly C NG NA +Acetic Acid acetate C NG NA +Succinic Acid succinate C NG NA +L-Tartaric Acid C NG NA +Propionic Acid C NG NA +Pyruvic Acid pyruvate C G NA +Mono Methyl Succinate C NG NA +L-Alaninamide C NG NA +L-Serine L-serine C NG NA +Formic Acid formate C NG NA +γ-Amino Butyric Acid gamma-aminobutyrate C NG NA +Oxalo malicAcid 3-oxalomalate(3-) C G NA +Glycyl-L-Glutamic Acid C NG NA +β-Hydroxy Butyric Acid C NG NA +D-Mannitol Mannitol C NG NA +D-Lactic Acid Methyl Ester C NG NA +Adonitol (Ribitol) C NG NA +D-Arabitol C NG NA +L-Glutamine L-glutamine C NG NA +Succinamic Acid C NG NA +Bromo Succinic Acid C NG NA +L-L eucine L-leucine C NG NA +D-Xylose D-xylose C G NA +L-Valine L-valine C NG NA +D-Sorbitol D-glucitol C NG NA +L-Asparagine L-asparagine C NG NA +Glycyl-L-Proline C NG NA +2-Aminoethanol (Ethanol amine) ethanolamine C NG NA +D-Ribose D-ribose C G NA +Glycyl-L-Aspartic Acid C NG NA +D-Galacturonic Acid D-galacturonate C NG NA +Uridine uridine C NG NA +L-Proline L-proline C NG NA +L-Galactonic Acid-γ-Lactone C NG NA +D-Mannose D-mannose C G NA +δ-Amino Valeric Acid C NG NA +α-Hydroxy GlutaricAcid-γ-Lactone C NG NA +α-D-Glucose D-glucose C G NA +D-Psicose C NG NA +D-Fructose D-fructose C G NA +L-Lyxose C G NA +L-Lysine L-lysine C NG NA +L-Isoleucine L-isoleucine C NG NA +α-Keto-Butyric Acid 2-oxobutanoate C NG NA +α-Hydroxy Butyric Acid C NG NA +α-Keto Valeric Acid C NG NA +3-0-β-D Galacto-pyranosyl-D-Arabinose C NG NA +Acetoacetic Acid acetoacetate C G NA +Glyoxylic Acid glyoxylate C NG NA +Tween 20 C NG NA +Palatinose 6-O-alpha-D-glucopyranosyl-D-fructofuranose C G NA +Dextrin Dextrin C NG NA +3-Hydroxy 2-Butanone C NG NA +5-Keto-D-Gluconic Acid 5-dehydro-D-gluconate C G NA +Tyramine C NG NA +p-Hydroxy Phenyl Acetic Acid (4-Hydroxyphenylacetate) C NG NA +Glucuronamide C G NA +M-Tartaric Acid C NG NA +Inosine inosine C NG NA +Citramalic Acid C NG NA +Glycolic Acid glycolate C NG NA +Melibionic Acid C NG NA +D-Tartaric Acid C NG NA +Glycerol glycerol C NG NA +Mucic Acid C NG NA +3-Methyl Glucose C NG NA +D-Fructose-6-Phosphate D-fructose 6-phosphate C NG NA +D-Tagatose D-tagatose C G NA +N-Acetyl-L-Glutamic Acid N-acetyl-L-glutamate C NG NA +Turanose turanose C G NA +D-Glucose-6-Phosphate D-glucose 6-phosphate C NG NA +L-Sorbose L-sorbose C NG NA +γ-Hydroxy Butyric Acid C NG NA +N-Acetyl-D-Glucosamine N-Acetyl-D-glucosamine C NG NA +β-Methyl-D-Glucuronic Acid C NG NA +Dulcitol (Galactitol) C NG NA +D-Arabinose D-arabinose C G NA +N-Acetyl-β-D-Mannosamine C NG NA +D-Glucosaminic Acid C NG NA +D-Melezitose C NG NA +D-Cellobiose C NG NA +Putrescine putrescine C NG NA +Tween 80 C NG NA +Quinic Acid C NG NA +Tricarballylic Acid C NG NA +β-D-Allose C NG NA +Chondroitin Sulfate C C NG NA +α-Methyl-D Galactoside C NG NA +Maltotriose alpha-maltotriose C G NA +β-Methyl-D-Glucoside C NG NA +Tween 40 C NG NA +Glycogen glycogen C NG NA +M-Inositol myo-inositol C NG NA +Sucrose sucrose C G NA +D-Saccharic Acid D-Glucarate C NG NA +Pectin pectin C NG NA +D-Glucose-1-Phosphate D-glucose 1-phosphate C NG NA +Hydroxy-L Proline C NG NA +D-Ribono-1,4-Lactone C NG NA +L-Pyroglutamic Acid 5-oxo-L-proline C NG NA +Lactulose C NG NA +D-Raffinose raffinose C NG NA +Maltose maltose C G NA +L-Rhamnose C NG NA +D-Galactose D-galactose C G NA +α-D-Lactose C NG NA +N-Acetyl-D-Galactosamine C NG NA +2,3-Butanediol C NG NA +1,2-Propanediol C NG NA +Amygdalin C NG NA +Malonic Acid C NG NA +D-Melibiose melibiose C NG NA +D-Gluconic Acid D-gluconate C NG NA +D.L-Octopamine C NG NA +D-Aspartate C NG NA +Gelatin C NG NA +L-Aspartic Acid L-aspartate C NG NA +L-Ornithine C NG NA +Salicin C NG NA +L-Arabinose L-arabinose C G NA +L-Histidine L-histidine C NG NA +D-Glucuronic Acid C NG NA +L-Glucose C NG NA +N-AcetylNeuraminic Acid C NG NA +β-Methyl-D-Galactoside C NG NA +Stachyose C NG NA +Maltitol C NG NA +Acetamide C NG NA +I-Erythritol C NG NA +Lactitol C NG NA +N-Acetyl-D-Glucosaminitol C NG NA +α-Methyl-D-Glucoside methyl alpha-D-glucopyranoside C G NA +D,L-Carnitine C NG NA +D,L-α-Glycerol-Phosphate glycerol 3-phosphate C NG NA +Sedoheptulosan C NG NA +β-Methyl-D-Xyloside C NG NA +β-Cyclodextrin C NG NA +L-Arginine L-arginine C NG NA +α-Methyl-D-Mannoside C NG NA +Gentiobiose C NG NA +L-Fucose C NG NA +L-T hreonine L-threonine C NG NA +L-Phenylalanine L-phenylalanine C NG NA +Citric Acid citrate C NG NA +α-Cyclodextrin C NG NA +Citraconic Acid C NG NA +L-Arabitol L-arabinitol C NG NA +D-Trehalose trehalose C NG NA +γ-Cyclodextrin C NG NA +L-Methionine L-methionine C NG NA +Inulin C G NA +D-Fucose C NG NA +D-Galactonic Acid-γ-Lactone C NG NA +L-Homoserine L-homoserine C NG NA +Oxalic Acid Oxalate C NG NA +Arbutin C NG NA +Laminarin C G NA +Caproic Acid hexanoate C NG NA +Phenylethyl-amine C NG NA +Xylitol xylitol C NG NA +m-Hydroxy Phenyl Acetic Acid C NG NA +Sec-Butylamine C NG NA +D-Glucosamine D-Glucosamine C G NA +Sebacic Acid C NG NA +Mannan mannan C NG NA +Dihydroxy Acetone glycerone C G NA +2-Deoxy Adenosine 2'-deoxyadenosine C NG NA +Adenosine adenosine C NG NA +D-Alanine C NG NA +D-Serine D-Serine C NG NA +2,3-Butanone H12 diacetyl C NG NA +D-Threonine C NG NA +Itaconic Acid itaconate C NG NA +2-Deoxy-D-Ribose 2-deoxy-D-ribose C G NA +4-Hydroxy Benzoic Acid 4-hydroxybenzoate C NG NA +Capric Acid decanoate C NG NA +Sorbic Acid C G NA +2-Hydroxy Benzoic Acid C NG NA +Glycine L-glycine C NG NA +Uric Acid N NG NA +Ala-Gln Ala-Gln N G NA +Ala-Leu Ala-Leu N G NA +Ala-Gly Ala-Gly N G NA +Xanthine 9H-xanthine N NG NA +D,L-Lactamide N NG NA +Cytosine cytosine N G NA +Gly-Gln Gly-Gln N G NA +Guanine guanine N NG NA +Ethylenediamine N NG NA +Ala-His Ala-His N G NA +Allantoin allantoin N G NA +Parabanic Acid N G NA +L-Alanine L-alanine N G NA +Guanosine guanosine N NG NA +L-Glutamine L-glutamine N G NA +L-Leucine L-leucine N G NA +Thymidine thymidine N NG NA +Gly-Asn Gly-Asn N G NA +Ala-Glu Ala-Glu N G NA +Thymine N NG NA +Cytidine cytidine N NG NA +Uracil uracil N NG NA +L-Asparagine L-asparagine N G NA +Gly-Met Gly-Met N G NA +Ala-Asp Ala-Asp N G NA +γ-Amino-N-Butyric Acid gamma-aminobutyrate N G NA +D-Alanine N NG NA +L-Serine L-serine N G NA +Urea urea N G NA +Gly-Glu Gly-Glu N G NA +Ala-Thr Ala-Thr N G NA +δ-Amino-N-Valeric Acid 5-Aminopentanoate N G NA +Putrescine putrescine N NG NA +Uridine uridine N NG NA +Met-Ala Met-Ala N G NA +Glucuronamide N NG NA +D-Serine D-Serine N NG NA +L-Lysine L-lysine N NG NA +L-Histidine L-histidine N G NA +D-Glutamic Acid N NG NA +Agmatine N NG NA +Ammonia ammonium N G NA +Xanthosine xanthosine N NG NA +Glycine L-glycine N G NA +L-Glutamic Acid L-glutamate N G NA +Ethanolamine ethanolamine N NG NA +D-Lysine N NG NA +L-Aspartic Acid L-aspartate N G NA +Alloxan N NG NA +N-Acetyl-D-Glucosamine N-Acetyl-D-glucosamine N NG NA +D-Aspartate N G NA +L-Cysteine L-cysteine N G NA +L-Proline L-proline N G NA +L-Isoleucine L-isoleucine N G NA +ε-Amino-N-Caproic Acid N NG NA +L-Tryptophan L-tryptophan N G NA +α-Amino-NValeric Acid N G NA +D-Asparagine N NG NA +L-Tyrosine L-tyrosine N G NA +Histamine N NG NA +D-Mannosamine N NG NA +D-Galactosamine N NG NA +L-Arginine L-arginine N G NA +L-Pyroglutamic Acid 5-oxo-L-proline N NG NA +L-Citrulline L-citrulline N G NA +Inosine inosine N NG NA +Formamide N NG NA +Ethylamine N NG NA +Acetamide N NG NA +L-Phenylalanine L-phenylalanine N G NA +Biuret N NG NA +N-Butylamine N NG NA +N-Acetyl-D-Galactosamine N NG NA +N-Acetyl-D ,L-Glutamic Acid N-acetyl-L-glutamate N G NA +N-Acetyl-D-Mannosamine N NG NA +L-Homoserine L-homoserine N G NA +Adenine adenine N NG NA +N-Amylamine N NG NA +Tyramine N NG NA +N-Phthaloyl-L-Glutamic Acid N NG NA +Methylamine N NG NA +L-Valine L-valine N G NA +Nitrate nitrate N NG NA +L-Ornithine ornithine N G NA +L-Threonine L-threonine N G NA +β-Phenylethyl-amine N NG NA +Nitrite Nitrite N NG NA +L-Methionine L-methionine N G NA +D,L-α-Amino-Caprylic Acid N G NA +D-Valine N NG NA +D-Glucosamine D-Glucosamine N NG NA +D,L-α-Amino-N-Butyric Acid 2-aminobutanoate N G NA +Adenosine adenosine N NG NA +Hydroxylamine N NG NA +Phosphoryl Choline choline phosphate P G NA +D,L-α-Glycerol Phosphate glycerol 1-phosphate P G NA +O-Phospho-D-Tyrosine P G NA +D-2-Phospho-Glyceric Acid 2-phospho-D-glyceric acid P G NA +Guanosine-5’-monophosphate GMP P G NA +O-Phospho-L-Serine 3-phospho-serine P G NA +O-Phospho-D-Serine O-phosphonatooxy-D-serine(2-) P G NA +Phosphate phosphate P G NA +Pyrophosphate diphosphate P G NA +Thiophosphate P G NA +Tripolyphosphate triphosphate P G NA +Uridine-5’-monophosphate UMP P G NA +Cytidine-5’-monophosphate CMP P G NA +Phosphoenol Pyruvate phosphoenolpyruvate P G NA +Trimetaphosphate P G NA +Phospho-L-Arginine N(omega)-phospho-L-arginine P G NA +Carbamyl Phosphate carbamoyl phosphate P G NA +O-Phosphoryl-Ethanolamine O-phosphoethanolamine P G NA +D-Glucosamine-6-Phosphate alpha-D-glucosamine 6-phosphate P G NA +Phosphocreatine N-phosphocreatine P G NA +Dithiophosphate P G NA +Thymidine-5’-monophosphate thymidine 5'-monophosphate P G NA +Thymidine-3 ’-monophosphate thymidine 3'-monophosphate P G NA +Cysteamine-S-Phosphate cysteamine S-phosphate P G NA +2-Deoxy-D-Glucose 6-Phosphate 2-deoxy-D-glucose 6-phosphate P NG NA +Guanosine-2’-monophosphate guanosine 2'-monophosphate P G NA +D-Glucose-6-Phosphate D-glucose 6-phosphate P G NA +β-Glycerol Phosphate glycerol 2-phosphate(2-) P G NA +Guanosine-3’-monophosphate 3'-GMP P G NA +Phospho-Glycolic Acid 2-phosphoglycolate P G NA +6-Phospho-Gluconic Acid 6-phospho-D-gluconate P G NA +D-Mannose-6-Phosphate D-mannose 6-phosphate P G NA +Cytidine-3’,5’-cyclic monophosphate 3',5'-cyclic CMP P NG NA +Cytidine-2’-monophosphate cytidine 2'-phosphate P G NA +Inositol Hexaphosphate myo-inositol hexakisphosphate P G NA +Guanosine-2’,3’-cyclic monophosphate 2',3'-cyclic GMP P G NA +O-Phospho-L-Tyrosine O(4)-phospho-L-tyrosine P G NA +O-Phospho-L-Threonine O-phospho-L-threonine P G NA +Cytidine-3’-monophosphate P NG NA +D-3-Phospho-Glyceric Acid 3-phosphonato-D-glycerate(3-) P G NA +Triethyl Phosphate P NG NA +Phosphono Acetic Acid P NG NA +Uridine-2’-monophosphate uridine 2'-phosphate P G NA +D-Glucose-1-Phosphate D-glucose 1-phosphate P G NA +Uridine-3’-monophosphate 3'-UMP P G NA +Cytidine-2’ ,3’-cyclic monophosphate 2',3'-cyclic CMP P G NA +2-Aminoethyl Phosphonic Acid P NG NA +Uridine-2’,3’-cyclic monophosphate 2',3'-cyclic UMP P G NA +Adenosine-2’-monophosphate adenosine 2'-phosphate P G NA +Adenosine-3’-monophosphate 3'-AMP P G NA +Adenosine-2’,3’-cyclic monophosphate 2',3'-cyclic AMP P G NA +Hypophosphite P NG NA +Guanosine-3’,5’-cyclic monophosphate 3',5'-cyclic GMP P NG NA +Thymidine 3’,5’-cyclic monophosphate P NG NA +D-Mannose-1-Phosphate D-mannose 1-phosphate P G NA +Urid ine-3’,5’-cyclic monophosphate P NG NA +Methylene Diphosphonic Acid P G NA +Adenosine-3’,5’-cyclic monophosphate 3',5'-cyclic AMP P NG NA +Adenosine-5’-monophosphate AMP P G NA +Sulfate sulphate S G NA +L-Cysteine L-cysteine S NG NA +Tetrathionate S NG NA +Thiosulfate thiosulfate S G NA +S-Methyl-L-Cysteine S G NA +Hypotaurine S NG NA +D-Methionine S NG NA +L-Cysteinyl-Glycine L-cysteinylglycine S NG NA +L-Methionine L-methionine S G NA +Glutathione glutathione S G NA +N-Acetyl-D,L-Methionine N(alpha)-acetyl-L-methionine S G NA +L-Methionine Sulfoxide L-Methionine S-oxide S NG NA +Glycyl-L-Methionine Gly-Met S G NA +Taurine tetrathionate S G NA +D-Cysteine S NG NA +Dithiophosphate S G NA +Cystathionine S NG NA +Cysteamine S NG NA +L-Cysteine Sulfinic Acid 3-sulfino-L-alanine S G NA +Thiophosphate S G NA +Lanthionine S NG NA +N-Acetyl-L-Cysteine N-acetyl-L-cysteine S G NA +Thiourea S G NA +1-Thio-β-D-Glucose S G NA +Taurocholic Acid taurocholic acid S NG NA +Butane Sulfonic Acid S G NA +D,L-Lipoamide lipoamide S G NA +L-Djenkolic Acid S NG NA +Methane Sulfonic Acid S NG NA +L-Cysteic Acid L-cysteate S G NA +p-Amino Benzene Sulfonic Acid S NG NA +D,L-Ethionine S NG NA +2-Hydroxyethane Sulfonic Acid 2-hydroxyethane-1-sulfonate S G NA +Tetramethylene Sulfone S NG NA +L-Methionine Sulfone L-Methionine S-oxide S G NA +Ethanol ethanol C G NA +D-Raffinose  raffinose C G NA +D-Cellobise C G NA +sodium acetate acetate C G NA diff --git a/ComplementaryScripts/modelCuration/SubstrateUsage.m b/ComplementaryScripts/modelCuration/SubstrateUsage.m new file mode 100644 index 00000000..1293fa2e --- /dev/null +++ b/ComplementaryScripts/modelCuration/SubstrateUsage.m @@ -0,0 +1,209 @@ +%This code is developed to automatically add +%exchange reactions for newmets and check whether it can be used as solo +%substrate. + +% Adds exchange reactions reactions +% +% USAGE: +% +% [metsCanBeUlitilized,metsCannotBeUltilized,newmodel] = substrateusage(model,biomass,substratelist,substratetype) +% +% INPUTS: +% model: Cobra model structure +% biomass: biomass reaction rxn ID +% +% +% OPTIONAL INPUTS: +% substratelist: substrates list +% substratetype: 'N'|'C'|'P'|'S' +% +% OUTPUT: +% newModel: COBRA model with added reactions +% +% .. Author: - Feiran Li 2018.05.04 +% As for the reference of Biolog_substrate_type.tsv, please find detailed information in the /ComplementaryData/experiment/Biolog.tsv +% NOTE: +% COBRA required. +% +% Feiran Li + + + +% Load model +cd .. +model = loadYeastModel; + +%%%%%substrateusage%%%%%%%%%%%%%%%%%%%%%%%%%%%% +fid2 = fopen('../ComplementaryData/modelCuration/Biolog_substrate.tsv'); +substrate = textscan(fid2,'%s %s %s %s %s %s','Delimiter','\t','HeaderLines',1); +SubBiologName = substrate{1}; +SubModelName = substrate{2}; +Subtype = substrate{3}; +BiologUsage = substrate{4}; +fclose(fid2); + + +ExchRxn = ''; +TransRxn = ''; +GapfillMets = ''; +TransEotherfillMets = ''; +TransECfillMets = ''; +FBAresult = ''; +for i = 1:length(SubBiologName) + newModel = model; + if ~isequal(SubModelName{i},'') + + metE = strcat(SubModelName{i},' [extracellular]'); + metC = strcat(SubModelName{i},' [cytoplasm]'); + [tmp,metEOrd] = ismember(metE,newModel.metNames); + [tmp,metCOrd] = ismember(metC,newModel.metNames); + %check whther exchange reaction for this met exists + duplicateE = find(sum(newModel.S ~= 0, 1) == 1 & any(newModel.S == -1, 1) & any(newModel.S(metEOrd(metEOrd~=0), :), 1)); + if ~isempty(duplicateE) + warning(['Model already has the same exchange reaction you tried to add: ', newModel.rxns{duplicateE}]); + %ExchRxn = [ExchRxn;newModel.metNames(metEOrd),newModel.rxns{duplicateE}]; + ExchRxn = newModel.rxns(duplicateE); + else + if metEOrd == 0 + newID = getNewIndex(newModel.mets); + metE_temp_ID = strcat('s_',newID,'[e]'); + newModel = addMetabolite(newModel,metE_temp_ID, ... + 'metName',metE); + %adding exchange rxn for this metE + newID = getNewIndex(newModel.rxns); + [newModel,rxnIDexists] = addReaction(newModel,['r_' newID],... + 'reactionName',['Exchange reaction, ',metE],... + 'metaboliteList',cellstr(metE_temp_ID),'stoichCoeffList',-1,... + 'lowerBound',0, 'upperBound',1000, 'subSystem', 'Exchange', 'checkDuplicate', false); + [tmp,metEOrd] = ismember(metE,newModel.metNames); + % ExchRxn=[ExchRxn;newModel.metNames(metEOrd),['r_' newID]]; + ExchRxn=['r_' newID]; + else + %adding exchange rxn for this metE + newID = getNewIndex(newModel.rxns); + [newModel,rxnIDexists] = addReaction(newModel,['r_' newID],... + 'reactionName',['Exchange reaction, ',metE],... + 'metaboliteList',newModel.mets(metEOrd),'stoichCoeffList',-1,... + 'lowerBound',0, 'upperBound',1000, 'subSystem', 'Exchange', 'checkDuplicate', false); + [tmp,metEOrd] = ismember(metE,newModel.metNames); + ExchRxn=['r_' newID]; + end + end + + + + %model prediction + newModel_test = newModel; + exchangeRxns = findExcRxns(newModel_test); + newModel_test.lb(exchangeRxns) = 0; + newModel_test.ub(exchangeRxns) = 1000; + desiredExchanges = {... + 'r_1992'; ... % 'oxygen exchange'; + 'r_1861'; ... % iron for test of expanded biomass def; + 'r_1832'; ... % hydrogen exchange; + }; + glcExchange = {'r_1714'};% D-glucose exchange' + amoExchange = {'r_1654'}; % 'ammonium exchange' + phoExchange = {'r_2005'}; % 'phosphate exchange' + sulExchange = {'r_2060'}; % 'phosphate exchange' + uptakeRxnIndexes = findRxnIDs(newModel_test,desiredExchanges); + amoExchangeIndex = findRxnIDs(newModel_test,amoExchange); + phoExchangeIndex = findRxnIDs(newModel_test,phoExchange); + glcExchangeIndex = findRxnIDs(newModel_test,glcExchange); + sulExchangeIndex = findRxnIDs(newModel_test,sulExchange); + if length(uptakeRxnIndexes) ~= 3 %5; + error('Not all exchange reactions were found.') + end + newModel_test.lb(uptakeRxnIndexes)=-1000; + [~,ord] = ismember(metE,ExchRxn); + if Subtype{i} == 'C' + newModel_test.lb(sulExchangeIndex)=-1000; + newModel_test.lb(amoExchangeIndex)=-1000; + newModel_test.lb(phoExchangeIndex)=-1000; + newModel_test.lb(glcExchangeIndex)=0; + SubRxnIndexes = findRxnIDs(newModel_test,ExchRxn); + newModel_test.lb(SubRxnIndexes)=-10; + elseif Subtype{i} == 'N' + newModel_test.lb(sulExchangeIndex)=-1000; + newModel_test.lb(amoExchangeIndex)=0; + newModel_test.lb(phoExchangeIndex)=-1000; + newModel_test.lb(glcExchangeIndex)=-10; + SubRxnIndexes = findRxnIDs(newModel_test,ExchRxn); + newModel_test.lb(SubRxnIndexes)=-10; + elseif Subtype{i} == 'P' + newModel_test.lb(sulExchangeIndex)=-1000; + newModel_test.lb(amoExchangeIndex)=-1000; + newModel_test.lb(phoExchangeIndex)=0; + newModel_test.lb(glcExchangeIndex)=-10; + SubRxnIndexes = findRxnIDs(newModel_test,ExchRxn); + newModel_test.lb(SubRxnIndexes)=-1000; + elseif Subtype{i} == 'S' + newModel_test.lb(sulExchangeIndex)=0; + newModel_test.lb(amoExchangeIndex)=-1000; + newModel_test.lb(phoExchangeIndex)=-1000; + newModel_test.lb(glcExchangeIndex)=-10; + SubRxnIndexes = findRxnIDs(newModel_test,ExchRxn); + newModel_test.lb(SubRxnIndexes)=-1000; + end + sol = optimizeCbModel(newModel_test); + if sol.obj > 0.000001 + model = newModel; + fprintf(metE,'can be used as solo substrate\n'); + FBAresult = [FBAresult;SubBiologName(i,1),SubModelName(i,1),Subtype(i,1),BiologUsage(i,1),'G']; + else + FBAresult = [FBAresult;SubBiologName(i,1),SubModelName(i,1),Subtype(i,1),BiologUsage(i,1),'NG']; + if strcmp(BiologUsage(i,1),'G') + fprintf(metE,'cannot be used as solo substrate, pathways need to be manually checked\n'); + if numel(find(newModel_test.S(metEOrd,:))) < 2 && metCOrd~=0 %metE appear only once without metC + warning(['Transport reaction should be added for:', newModel_test.metNames{metEOrd}]) + TransECfillMets = [TransECfillMets;newModel_test.metNames(metEOrd)]; + elseif numel(find(newModel_test.S(metEOrd,:))) < 2 && metCOrd ==0 %metE appear only once without metC + S = regexp(newModel_test.metNames{metEOrd}, ' [', 'split'); + met_temp = char(S(1)); + metEMapping = find(strncmp(met_temp,model.metNames,length(met_temp))); + if isempty(metEMapping) + warning(['mets only appear once, fill the gap for mets:', newModel_test.metNames{metEOrd}]) + GapfillMets = [GapfillMets;newModel_test.metNames(metEOrd)]; + else + TransEotherfillMets = [TransEotherfillMets;newModel_test.metNames(metEOrd);model.metNames(metEMapping)]; + end + end + end + end + else + FBAresult = [FBAresult;SubBiologName(i,1),SubModelName(i,1),Subtype(i,1),BiologUsage(i,1),'NG']; + end +end + + + + + + %save results +fid2 = fopen('../ComplementaryData/modelCuration/Biolog_substrate.tsv','w'); +formatSpec = '%s\t%s\t%s\t%s\t%s\n'; +fprintf(fid2,formatSpec,'Subtrate','Name_in_Model','Substrate_type','Growth_Biolog','Growth_Model'); +for i = 1:length(FBAresult) + fprintf(fid2,formatSpec,char(FBAresult(i,1)),char(FBAresult(i,2)),char(FBAresult(i,3)),char(FBAresult(i,4)),char(FBAresult(i,5))); + +end + +%save model +%model = newModel; +model = rmfield(model,'grRules'); +cd .. +saveYeastModel(model) +cd modelCuration + + + + + + + + + + + + + \ No newline at end of file From a8826a0074de650be3c8e1dd844c8911accbf93c Mon Sep 17 00:00:00 2001 From: FEIRANL Date: Sun, 26 Aug 2018 00:09:08 +0200 Subject: [PATCH 02/27] feat-data: Update model prediction Using SubstrateUsage.m to update model prediction of substrate usage --- .../modelCuration/Biolog_Substrate.tsv | 768 +++++++++--------- 1 file changed, 384 insertions(+), 384 deletions(-) diff --git a/ComplementaryData/modelCuration/Biolog_Substrate.tsv b/ComplementaryData/modelCuration/Biolog_Substrate.tsv index ab60202d..749af062 100644 --- a/ComplementaryData/modelCuration/Biolog_Substrate.tsv +++ b/ComplementaryData/modelCuration/Biolog_Substrate.tsv @@ -1,384 +1,384 @@ -subtaate Name_In_Model Substrate_type Growth_Biolog Growth_Model -L-Malic Acid (S)-malate C NG NA -L-Glutamic Acid L-glutamate C NG NA -Thymidine thymidine C NG NA -D-Malic Acid C NG NA -L-Alanine L-alanine C NG NA -Fumaric Acid fumarate C NG NA -L-Lactic Acid (S)-lactate C G NA -Butyric Acid butyrate C NG NA -Methyl Pyruvate C NG NA -α-Keto-Glutaric Acid 2-oxoglutarate C NG NA -D,L-Malic Acid C NG NA -L-Alanyl-Glycine Ala-Gly C NG NA -Acetic Acid acetate C NG NA -Succinic Acid succinate C NG NA -L-Tartaric Acid C NG NA -Propionic Acid C NG NA -Pyruvic Acid pyruvate C G NA -Mono Methyl Succinate C NG NA -L-Alaninamide C NG NA -L-Serine L-serine C NG NA -Formic Acid formate C NG NA -γ-Amino Butyric Acid gamma-aminobutyrate C NG NA -Oxalo malicAcid 3-oxalomalate(3-) C G NA -Glycyl-L-Glutamic Acid C NG NA -β-Hydroxy Butyric Acid C NG NA -D-Mannitol Mannitol C NG NA -D-Lactic Acid Methyl Ester C NG NA -Adonitol (Ribitol) C NG NA -D-Arabitol C NG NA -L-Glutamine L-glutamine C NG NA -Succinamic Acid C NG NA -Bromo Succinic Acid C NG NA -L-L eucine L-leucine C NG NA -D-Xylose D-xylose C G NA -L-Valine L-valine C NG NA -D-Sorbitol D-glucitol C NG NA -L-Asparagine L-asparagine C NG NA -Glycyl-L-Proline C NG NA -2-Aminoethanol (Ethanol amine) ethanolamine C NG NA -D-Ribose D-ribose C G NA -Glycyl-L-Aspartic Acid C NG NA -D-Galacturonic Acid D-galacturonate C NG NA -Uridine uridine C NG NA -L-Proline L-proline C NG NA -L-Galactonic Acid-γ-Lactone C NG NA -D-Mannose D-mannose C G NA -δ-Amino Valeric Acid C NG NA -α-Hydroxy GlutaricAcid-γ-Lactone C NG NA -α-D-Glucose D-glucose C G NA -D-Psicose C NG NA -D-Fructose D-fructose C G NA -L-Lyxose C G NA -L-Lysine L-lysine C NG NA -L-Isoleucine L-isoleucine C NG NA -α-Keto-Butyric Acid 2-oxobutanoate C NG NA -α-Hydroxy Butyric Acid C NG NA -α-Keto Valeric Acid C NG NA -3-0-β-D Galacto-pyranosyl-D-Arabinose C NG NA -Acetoacetic Acid acetoacetate C G NA -Glyoxylic Acid glyoxylate C NG NA -Tween 20 C NG NA -Palatinose 6-O-alpha-D-glucopyranosyl-D-fructofuranose C G NA -Dextrin Dextrin C NG NA -3-Hydroxy 2-Butanone C NG NA -5-Keto-D-Gluconic Acid 5-dehydro-D-gluconate C G NA -Tyramine C NG NA -p-Hydroxy Phenyl Acetic Acid (4-Hydroxyphenylacetate) C NG NA -Glucuronamide C G NA -M-Tartaric Acid C NG NA -Inosine inosine C NG NA -Citramalic Acid C NG NA -Glycolic Acid glycolate C NG NA -Melibionic Acid C NG NA -D-Tartaric Acid C NG NA -Glycerol glycerol C NG NA -Mucic Acid C NG NA -3-Methyl Glucose C NG NA -D-Fructose-6-Phosphate D-fructose 6-phosphate C NG NA -D-Tagatose D-tagatose C G NA -N-Acetyl-L-Glutamic Acid N-acetyl-L-glutamate C NG NA -Turanose turanose C G NA -D-Glucose-6-Phosphate D-glucose 6-phosphate C NG NA -L-Sorbose L-sorbose C NG NA -γ-Hydroxy Butyric Acid C NG NA -N-Acetyl-D-Glucosamine N-Acetyl-D-glucosamine C NG NA -β-Methyl-D-Glucuronic Acid C NG NA -Dulcitol (Galactitol) C NG NA -D-Arabinose D-arabinose C G NA -N-Acetyl-β-D-Mannosamine C NG NA -D-Glucosaminic Acid C NG NA -D-Melezitose C NG NA -D-Cellobiose C NG NA -Putrescine putrescine C NG NA -Tween 80 C NG NA -Quinic Acid C NG NA -Tricarballylic Acid C NG NA -β-D-Allose C NG NA -Chondroitin Sulfate C C NG NA -α-Methyl-D Galactoside C NG NA -Maltotriose alpha-maltotriose C G NA -β-Methyl-D-Glucoside C NG NA -Tween 40 C NG NA -Glycogen glycogen C NG NA -M-Inositol myo-inositol C NG NA -Sucrose sucrose C G NA -D-Saccharic Acid D-Glucarate C NG NA -Pectin pectin C NG NA -D-Glucose-1-Phosphate D-glucose 1-phosphate C NG NA -Hydroxy-L Proline C NG NA -D-Ribono-1,4-Lactone C NG NA -L-Pyroglutamic Acid 5-oxo-L-proline C NG NA -Lactulose C NG NA -D-Raffinose raffinose C NG NA -Maltose maltose C G NA -L-Rhamnose C NG NA -D-Galactose D-galactose C G NA -α-D-Lactose C NG NA -N-Acetyl-D-Galactosamine C NG NA -2,3-Butanediol C NG NA -1,2-Propanediol C NG NA -Amygdalin C NG NA -Malonic Acid C NG NA -D-Melibiose melibiose C NG NA -D-Gluconic Acid D-gluconate C NG NA -D.L-Octopamine C NG NA -D-Aspartate C NG NA -Gelatin C NG NA -L-Aspartic Acid L-aspartate C NG NA -L-Ornithine C NG NA -Salicin C NG NA -L-Arabinose L-arabinose C G NA -L-Histidine L-histidine C NG NA -D-Glucuronic Acid C NG NA -L-Glucose C NG NA -N-AcetylNeuraminic Acid C NG NA -β-Methyl-D-Galactoside C NG NA -Stachyose C NG NA -Maltitol C NG NA -Acetamide C NG NA -I-Erythritol C NG NA -Lactitol C NG NA -N-Acetyl-D-Glucosaminitol C NG NA -α-Methyl-D-Glucoside methyl alpha-D-glucopyranoside C G NA -D,L-Carnitine C NG NA -D,L-α-Glycerol-Phosphate glycerol 3-phosphate C NG NA -Sedoheptulosan C NG NA -β-Methyl-D-Xyloside C NG NA -β-Cyclodextrin C NG NA -L-Arginine L-arginine C NG NA -α-Methyl-D-Mannoside C NG NA -Gentiobiose C NG NA -L-Fucose C NG NA -L-T hreonine L-threonine C NG NA -L-Phenylalanine L-phenylalanine C NG NA -Citric Acid citrate C NG NA -α-Cyclodextrin C NG NA -Citraconic Acid C NG NA -L-Arabitol L-arabinitol C NG NA -D-Trehalose trehalose C NG NA -γ-Cyclodextrin C NG NA -L-Methionine L-methionine C NG NA -Inulin C G NA -D-Fucose C NG NA -D-Galactonic Acid-γ-Lactone C NG NA -L-Homoserine L-homoserine C NG NA -Oxalic Acid Oxalate C NG NA -Arbutin C NG NA -Laminarin C G NA -Caproic Acid hexanoate C NG NA -Phenylethyl-amine C NG NA -Xylitol xylitol C NG NA -m-Hydroxy Phenyl Acetic Acid C NG NA -Sec-Butylamine C NG NA -D-Glucosamine D-Glucosamine C G NA -Sebacic Acid C NG NA -Mannan mannan C NG NA -Dihydroxy Acetone glycerone C G NA -2-Deoxy Adenosine 2'-deoxyadenosine C NG NA -Adenosine adenosine C NG NA -D-Alanine C NG NA -D-Serine D-Serine C NG NA -2,3-Butanone H12 diacetyl C NG NA -D-Threonine C NG NA -Itaconic Acid itaconate C NG NA -2-Deoxy-D-Ribose 2-deoxy-D-ribose C G NA -4-Hydroxy Benzoic Acid 4-hydroxybenzoate C NG NA -Capric Acid decanoate C NG NA -Sorbic Acid C G NA -2-Hydroxy Benzoic Acid C NG NA -Glycine L-glycine C NG NA -Uric Acid N NG NA -Ala-Gln Ala-Gln N G NA -Ala-Leu Ala-Leu N G NA -Ala-Gly Ala-Gly N G NA -Xanthine 9H-xanthine N NG NA -D,L-Lactamide N NG NA -Cytosine cytosine N G NA -Gly-Gln Gly-Gln N G NA -Guanine guanine N NG NA -Ethylenediamine N NG NA -Ala-His Ala-His N G NA -Allantoin allantoin N G NA -Parabanic Acid N G NA -L-Alanine L-alanine N G NA -Guanosine guanosine N NG NA -L-Glutamine L-glutamine N G NA -L-Leucine L-leucine N G NA -Thymidine thymidine N NG NA -Gly-Asn Gly-Asn N G NA -Ala-Glu Ala-Glu N G NA -Thymine N NG NA -Cytidine cytidine N NG NA -Uracil uracil N NG NA -L-Asparagine L-asparagine N G NA -Gly-Met Gly-Met N G NA -Ala-Asp Ala-Asp N G NA -γ-Amino-N-Butyric Acid gamma-aminobutyrate N G NA -D-Alanine N NG NA -L-Serine L-serine N G NA -Urea urea N G NA -Gly-Glu Gly-Glu N G NA -Ala-Thr Ala-Thr N G NA -δ-Amino-N-Valeric Acid 5-Aminopentanoate N G NA -Putrescine putrescine N NG NA -Uridine uridine N NG NA -Met-Ala Met-Ala N G NA -Glucuronamide N NG NA -D-Serine D-Serine N NG NA -L-Lysine L-lysine N NG NA -L-Histidine L-histidine N G NA -D-Glutamic Acid N NG NA -Agmatine N NG NA -Ammonia ammonium N G NA -Xanthosine xanthosine N NG NA -Glycine L-glycine N G NA -L-Glutamic Acid L-glutamate N G NA -Ethanolamine ethanolamine N NG NA -D-Lysine N NG NA -L-Aspartic Acid L-aspartate N G NA -Alloxan N NG NA -N-Acetyl-D-Glucosamine N-Acetyl-D-glucosamine N NG NA -D-Aspartate N G NA -L-Cysteine L-cysteine N G NA -L-Proline L-proline N G NA -L-Isoleucine L-isoleucine N G NA -ε-Amino-N-Caproic Acid N NG NA -L-Tryptophan L-tryptophan N G NA -α-Amino-NValeric Acid N G NA -D-Asparagine N NG NA -L-Tyrosine L-tyrosine N G NA -Histamine N NG NA -D-Mannosamine N NG NA -D-Galactosamine N NG NA -L-Arginine L-arginine N G NA -L-Pyroglutamic Acid 5-oxo-L-proline N NG NA -L-Citrulline L-citrulline N G NA -Inosine inosine N NG NA -Formamide N NG NA -Ethylamine N NG NA -Acetamide N NG NA -L-Phenylalanine L-phenylalanine N G NA -Biuret N NG NA -N-Butylamine N NG NA -N-Acetyl-D-Galactosamine N NG NA -N-Acetyl-D ,L-Glutamic Acid N-acetyl-L-glutamate N G NA -N-Acetyl-D-Mannosamine N NG NA -L-Homoserine L-homoserine N G NA -Adenine adenine N NG NA -N-Amylamine N NG NA -Tyramine N NG NA -N-Phthaloyl-L-Glutamic Acid N NG NA -Methylamine N NG NA -L-Valine L-valine N G NA -Nitrate nitrate N NG NA -L-Ornithine ornithine N G NA -L-Threonine L-threonine N G NA -β-Phenylethyl-amine N NG NA -Nitrite Nitrite N NG NA -L-Methionine L-methionine N G NA -D,L-α-Amino-Caprylic Acid N G NA -D-Valine N NG NA -D-Glucosamine D-Glucosamine N NG NA -D,L-α-Amino-N-Butyric Acid 2-aminobutanoate N G NA -Adenosine adenosine N NG NA -Hydroxylamine N NG NA -Phosphoryl Choline choline phosphate P G NA -D,L-α-Glycerol Phosphate glycerol 1-phosphate P G NA -O-Phospho-D-Tyrosine P G NA -D-2-Phospho-Glyceric Acid 2-phospho-D-glyceric acid P G NA -Guanosine-5’-monophosphate GMP P G NA -O-Phospho-L-Serine 3-phospho-serine P G NA -O-Phospho-D-Serine O-phosphonatooxy-D-serine(2-) P G NA -Phosphate phosphate P G NA -Pyrophosphate diphosphate P G NA -Thiophosphate P G NA -Tripolyphosphate triphosphate P G NA -Uridine-5’-monophosphate UMP P G NA -Cytidine-5’-monophosphate CMP P G NA -Phosphoenol Pyruvate phosphoenolpyruvate P G NA -Trimetaphosphate P G NA -Phospho-L-Arginine N(omega)-phospho-L-arginine P G NA -Carbamyl Phosphate carbamoyl phosphate P G NA -O-Phosphoryl-Ethanolamine O-phosphoethanolamine P G NA -D-Glucosamine-6-Phosphate alpha-D-glucosamine 6-phosphate P G NA -Phosphocreatine N-phosphocreatine P G NA -Dithiophosphate P G NA -Thymidine-5’-monophosphate thymidine 5'-monophosphate P G NA -Thymidine-3 ’-monophosphate thymidine 3'-monophosphate P G NA -Cysteamine-S-Phosphate cysteamine S-phosphate P G NA -2-Deoxy-D-Glucose 6-Phosphate 2-deoxy-D-glucose 6-phosphate P NG NA -Guanosine-2’-monophosphate guanosine 2'-monophosphate P G NA -D-Glucose-6-Phosphate D-glucose 6-phosphate P G NA -β-Glycerol Phosphate glycerol 2-phosphate(2-) P G NA -Guanosine-3’-monophosphate 3'-GMP P G NA -Phospho-Glycolic Acid 2-phosphoglycolate P G NA -6-Phospho-Gluconic Acid 6-phospho-D-gluconate P G NA -D-Mannose-6-Phosphate D-mannose 6-phosphate P G NA -Cytidine-3’,5’-cyclic monophosphate 3',5'-cyclic CMP P NG NA -Cytidine-2’-monophosphate cytidine 2'-phosphate P G NA -Inositol Hexaphosphate myo-inositol hexakisphosphate P G NA -Guanosine-2’,3’-cyclic monophosphate 2',3'-cyclic GMP P G NA -O-Phospho-L-Tyrosine O(4)-phospho-L-tyrosine P G NA -O-Phospho-L-Threonine O-phospho-L-threonine P G NA -Cytidine-3’-monophosphate P NG NA -D-3-Phospho-Glyceric Acid 3-phosphonato-D-glycerate(3-) P G NA -Triethyl Phosphate P NG NA -Phosphono Acetic Acid P NG NA -Uridine-2’-monophosphate uridine 2'-phosphate P G NA -D-Glucose-1-Phosphate D-glucose 1-phosphate P G NA -Uridine-3’-monophosphate 3'-UMP P G NA -Cytidine-2’ ,3’-cyclic monophosphate 2',3'-cyclic CMP P G NA -2-Aminoethyl Phosphonic Acid P NG NA -Uridine-2’,3’-cyclic monophosphate 2',3'-cyclic UMP P G NA -Adenosine-2’-monophosphate adenosine 2'-phosphate P G NA -Adenosine-3’-monophosphate 3'-AMP P G NA -Adenosine-2’,3’-cyclic monophosphate 2',3'-cyclic AMP P G NA -Hypophosphite P NG NA -Guanosine-3’,5’-cyclic monophosphate 3',5'-cyclic GMP P NG NA -Thymidine 3’,5’-cyclic monophosphate P NG NA -D-Mannose-1-Phosphate D-mannose 1-phosphate P G NA -Urid ine-3’,5’-cyclic monophosphate P NG NA -Methylene Diphosphonic Acid P G NA -Adenosine-3’,5’-cyclic monophosphate 3',5'-cyclic AMP P NG NA -Adenosine-5’-monophosphate AMP P G NA -Sulfate sulphate S G NA -L-Cysteine L-cysteine S NG NA -Tetrathionate S NG NA -Thiosulfate thiosulfate S G NA -S-Methyl-L-Cysteine S G NA -Hypotaurine S NG NA -D-Methionine S NG NA -L-Cysteinyl-Glycine L-cysteinylglycine S NG NA -L-Methionine L-methionine S G NA -Glutathione glutathione S G NA -N-Acetyl-D,L-Methionine N(alpha)-acetyl-L-methionine S G NA -L-Methionine Sulfoxide L-Methionine S-oxide S NG NA -Glycyl-L-Methionine Gly-Met S G NA -Taurine tetrathionate S G NA -D-Cysteine S NG NA -Dithiophosphate S G NA -Cystathionine S NG NA -Cysteamine S NG NA -L-Cysteine Sulfinic Acid 3-sulfino-L-alanine S G NA -Thiophosphate S G NA -Lanthionine S NG NA -N-Acetyl-L-Cysteine N-acetyl-L-cysteine S G NA -Thiourea S G NA -1-Thio-β-D-Glucose S G NA -Taurocholic Acid taurocholic acid S NG NA -Butane Sulfonic Acid S G NA -D,L-Lipoamide lipoamide S G NA -L-Djenkolic Acid S NG NA -Methane Sulfonic Acid S NG NA -L-Cysteic Acid L-cysteate S G NA -p-Amino Benzene Sulfonic Acid S NG NA -D,L-Ethionine S NG NA -2-Hydroxyethane Sulfonic Acid 2-hydroxyethane-1-sulfonate S G NA -Tetramethylene Sulfone S NG NA -L-Methionine Sulfone L-Methionine S-oxide S G NA -Ethanol ethanol C G NA -D-Raffinose  raffinose C G NA -D-Cellobise C G NA -sodium acetate acetate C G NA +Subtrate Name_in_Model Substrate_type Growth_Biolog Growth_Model +L-Malic Acid (S)-malate C NG G +L-Glutamic Acid L-glutamate C NG G +Thymidine thymidine C NG NG +D-Malic Acid C NG NG +L-Alanine L-alanine C NG G +Fumaric Acid fumarate C NG G +L-Lactic Acid (S)-lactate C G G +Butyric Acid butyrate C NG NG +Methyl Pyruvate C NG NG +α-Keto-Glutaric Acid 2-oxoglutarate C NG G +D,L-Malic Acid C NG NG +L-Alanyl-Glycine Ala-Gly C NG NG +Acetic Acid acetate C NG G +Succinic Acid succinate C NG G +L-Tartaric Acid C NG NG +Propionic Acid C NG NG +Pyruvic Acid pyruvate C G G +Mono Methyl Succinate C NG NG +L-Alaninamide C NG NG +L-Serine L-serine C NG G +Formic Acid formate C NG G +γ-Amino Butyric Acid gamma-aminobutyrate C NG G +Oxalo malicAcid 3-oxalomalate(3-) C G NG +Glycyl-L-Glutamic Acid C NG NG +β-Hydroxy Butyric Acid C NG NG +D-Mannitol Mannitol C NG NG +D-Lactic Acid Methyl Ester C NG NG +Adonitol (Ribitol) C NG NG +D-Arabitol C NG NG +L-Glutamine L-glutamine C NG G +Succinamic Acid C NG NG +Bromo Succinic Acid C NG NG +L-L eucine L-leucine C NG NG +D-Xylose D-xylose C G G +L-Valine L-valine C NG NG +D-Sorbitol D-glucitol C NG G +L-Asparagine L-asparagine C NG G +Glycyl-L-Proline C NG NG +2-Aminoethanol (Ethanol amine) ethanolamine C NG NG +D-Ribose D-ribose C G G +Glycyl-L-Aspartic Acid C NG NG +D-Galacturonic Acid D-galacturonate C NG NG +Uridine uridine C NG NG +L-Proline L-proline C NG G +L-Galactonic Acid-γ-Lactone C NG NG +D-Mannose D-mannose C G G +δ-Amino Valeric Acid C NG NG +α-Hydroxy GlutaricAcid-γ-Lactone C NG NG +α-D-Glucose D-glucose C G G +D-Psicose C NG NG +D-Fructose D-fructose C G G +L-Lyxose C G NG +L-Lysine L-lysine C NG NG +L-Isoleucine L-isoleucine C NG NG +α-Keto-Butyric Acid 2-oxobutanoate C NG NG +α-Hydroxy Butyric Acid C NG NG +α-Keto Valeric Acid C NG NG +3-0-β-D Galacto-pyranosyl-D-Arabinose C NG NG +Acetoacetic Acid acetoacetate C G NG +Glyoxylic Acid glyoxylate C NG G +Tween 20 C NG NG +Palatinose 6-O-alpha-D-glucopyranosyl-D-fructofuranose C G NG +Dextrin Dextrin C NG NG +3-Hydroxy 2-Butanone C NG NG +5-Keto-D-Gluconic Acid 5-dehydro-D-gluconate C G NG +Tyramine C NG NG +p-Hydroxy Phenyl Acetic Acid (4-Hydroxyphenylacetate) C NG NG +Glucuronamide C G NG +M-Tartaric Acid C NG NG +Inosine inosine C NG G +Citramalic Acid C NG NG +Glycolic Acid glycolate C NG NG +Melibionic Acid C NG NG +D-Tartaric Acid C NG NG +Glycerol glycerol C NG G +Mucic Acid C NG NG +3-Methyl Glucose C NG NG +D-Fructose-6-Phosphate D-fructose 6-phosphate C NG NG +D-Tagatose D-tagatose C G NG +N-Acetyl-L-Glutamic Acid N-acetyl-L-glutamate C NG NG +Turanose turanose C G NG +D-Glucose-6-Phosphate D-glucose 6-phosphate C NG NG +L-Sorbose L-sorbose C NG NG +γ-Hydroxy Butyric Acid C NG NG +N-Acetyl-D-Glucosamine N-Acetyl-D-glucosamine C NG NG +β-Methyl-D-Glucuronic Acid C NG NG +Dulcitol (Galactitol) C NG NG +D-Arabinose D-arabinose C G NG +N-Acetyl-β-D-Mannosamine C NG NG +D-Glucosaminic Acid C NG NG +D-Melezitose C NG NG +D-Cellobiose C NG NG +Putrescine putrescine C NG NG +Tween 80 C NG NG +Quinic Acid C NG NG +Tricarballylic Acid C NG NG +β-D-Allose C NG NG +Chondroitin Sulfate C C NG NG +α-Methyl-D Galactoside C NG NG +Maltotriose alpha-maltotriose C G NG +β-Methyl-D-Glucoside C NG NG +Tween 40 C NG NG +Glycogen glycogen C NG NG +M-Inositol myo-inositol C NG NG +Sucrose sucrose C G G +D-Saccharic Acid D-Glucarate C NG NG +Pectin pectin C NG NG +D-Glucose-1-Phosphate D-glucose 1-phosphate C NG NG +Hydroxy-L Proline C NG NG +D-Ribono-1,4-Lactone C NG NG +L-Pyroglutamic Acid 5-oxo-L-proline C NG NG +Lactulose C NG NG +D-Raffinose raffinose C NG G +Maltose maltose C G G +L-Rhamnose C NG NG +D-Galactose D-galactose C G G +α-D-Lactose C NG NG +N-Acetyl-D-Galactosamine C NG NG +2,3-Butanediol C NG NG +1,2-Propanediol C NG NG +Amygdalin C NG NG +Malonic Acid C NG NG +D-Melibiose melibiose C NG NG +D-Gluconic Acid D-gluconate C NG NG +D.L-Octopamine C NG NG +D-Aspartate C NG NG +Gelatin C NG NG +L-Aspartic Acid L-aspartate C NG G +L-Ornithine C NG NG +Salicin C NG NG +L-Arabinose L-arabinose C G NG +L-Histidine L-histidine C NG NG +D-Glucuronic Acid C NG NG +L-Glucose C NG NG +N-AcetylNeuraminic Acid C NG NG +β-Methyl-D-Galactoside C NG NG +Stachyose C NG NG +Maltitol C NG NG +Acetamide C NG NG +I-Erythritol C NG NG +Lactitol C NG NG +N-Acetyl-D-Glucosaminitol C NG NG +α-Methyl-D-Glucoside methyl alpha-D-glucopyranoside C G NG +D,L-Carnitine C NG NG +D,L-α-Glycerol-Phosphate glycerol 3-phosphate C NG NG +Sedoheptulosan C NG NG +β-Methyl-D-Xyloside C NG NG +β-Cyclodextrin C NG NG +L-Arginine L-arginine C NG G +α-Methyl-D-Mannoside C NG NG +Gentiobiose C NG NG +L-Fucose C NG NG +L-T hreonine L-threonine C NG G +L-Phenylalanine L-phenylalanine C NG NG +Citric Acid citrate C NG G +α-Cyclodextrin C NG NG +Citraconic Acid C NG NG +L-Arabitol L-arabinitol C NG NG +D-Trehalose trehalose C NG G +γ-Cyclodextrin C NG NG +L-Methionine L-methionine C NG NG +Inulin C G NG +D-Fucose C NG NG +D-Galactonic Acid-γ-Lactone C NG NG +L-Homoserine L-homoserine C NG G +Oxalic Acid Oxalate C NG NG +Arbutin C NG NG +Laminarin C G NG +Caproic Acid hexanoate C NG NG +Phenylethyl-amine C NG NG +Xylitol xylitol C NG G +m-Hydroxy Phenyl Acetic Acid C NG NG +Sec-Butylamine C NG NG +D-Glucosamine D-Glucosamine C G NG +Sebacic Acid C NG NG +Mannan mannan C NG NG +Dihydroxy Acetone glycerone C G NG +2-Deoxy Adenosine 2'-deoxyadenosine C NG NG +Adenosine adenosine C NG G +D-Alanine C NG NG +D-Serine D-Serine C NG NG +2,3-Butanone H12 diacetyl C NG NG +D-Threonine C NG NG +Itaconic Acid itaconate C NG NG +2-Deoxy-D-Ribose 2-deoxy-D-ribose C G NG +4-Hydroxy Benzoic Acid 4-hydroxybenzoate C NG NG +Capric Acid decanoate C NG G +Sorbic Acid C G NG +2-Hydroxy Benzoic Acid C NG NG +Glycine L-glycine C NG G +Uric Acid N NG NG +Ala-Gln Ala-Gln N G NG +Ala-Leu Ala-Leu N G NG +Ala-Gly Ala-Gly N G NG +Xanthine 9H-xanthine N NG NG +D,L-Lactamide N NG NG +Cytosine cytosine N G G +Gly-Gln Gly-Gln N G NG +Guanine guanine N NG G +Ethylenediamine N NG NG +Ala-His Ala-His N G NG +Allantoin allantoin N G G +Parabanic Acid N G NG +L-Alanine L-alanine N G G +Guanosine guanosine N NG G +L-Glutamine L-glutamine N G G +L-Leucine L-leucine N G G +Thymidine thymidine N NG NG +Gly-Asn Gly-Asn N G NG +Ala-Glu Ala-Glu N G NG +Thymine N NG NG +Cytidine cytidine N NG G +Uracil uracil N NG NG +L-Asparagine L-asparagine N G G +Gly-Met Gly-Met N G NG +Ala-Asp Ala-Asp N G NG +γ-Amino-N-Butyric Acid gamma-aminobutyrate N G G +D-Alanine N NG NG +L-Serine L-serine N G G +Urea urea N G G +Gly-Glu Gly-Glu N G NG +Ala-Thr Ala-Thr N G NG +δ-Amino-N-Valeric Acid 5-Aminopentanoate N G NG +Putrescine putrescine N NG NG +Uridine uridine N NG NG +Met-Ala Met-Ala N G NG +Glucuronamide N NG NG +D-Serine D-Serine N NG NG +L-Lysine L-lysine N NG NG +L-Histidine L-histidine N G NG +D-Glutamic Acid N NG NG +Agmatine N NG NG +Ammonia ammonium N G G +Xanthosine xanthosine N NG NG +Glycine L-glycine N G G +L-Glutamic Acid L-glutamate N G G +Ethanolamine ethanolamine N NG NG +D-Lysine N NG NG +L-Aspartic Acid L-aspartate N G G +Alloxan N NG NG +N-Acetyl-D-Glucosamine N-Acetyl-D-glucosamine N NG NG +D-Aspartate N G NG +L-Cysteine L-cysteine N G NG +L-Proline L-proline N G G +L-Isoleucine L-isoleucine N G G +ε-Amino-N-Caproic Acid N NG NG +L-Tryptophan L-tryptophan N G G +α-Amino-NValeric Acid N G NG +D-Asparagine N NG NG +L-Tyrosine L-tyrosine N G NG +Histamine N NG NG +D-Mannosamine N NG NG +D-Galactosamine N NG NG +L-Arginine L-arginine N G G +L-Pyroglutamic Acid 5-oxo-L-proline N NG NG +L-Citrulline L-citrulline N G NG +Inosine inosine N NG NG +Formamide N NG NG +Ethylamine N NG NG +Acetamide N NG NG +L-Phenylalanine L-phenylalanine N G G +Biuret N NG NG +N-Butylamine N NG NG +N-Acetyl-D-Galactosamine N NG NG +N-Acetyl-D ,L-Glutamic Acid N-acetyl-L-glutamate N G NG +N-Acetyl-D-Mannosamine N NG NG +L-Homoserine L-homoserine N G G +Adenine adenine N NG G +N-Amylamine N NG NG +Tyramine N NG NG +N-Phthaloyl-L-Glutamic Acid N NG NG +Methylamine N NG NG +L-Valine L-valine N G G +Nitrate nitrate N NG NG +L-Ornithine ornithine N G G +L-Threonine L-threonine N G G +β-Phenylethyl-amine N NG NG +Nitrite Nitrite N NG NG +L-Methionine L-methionine N G NG +D,L-α-Amino-Caprylic Acid N G NG +D-Valine N NG NG +D-Glucosamine D-Glucosamine N NG NG +D,L-α-Amino-N-Butyric Acid 2-aminobutanoate N G NG +Adenosine adenosine N NG G +Hydroxylamine N NG NG +Phosphoryl Choline choline phosphate P G NG +D,L-α-Glycerol Phosphate glycerol 1-phosphate P G NG +O-Phospho-D-Tyrosine P G NG +D-2-Phospho-Glyceric Acid 2-phospho-D-glyceric acid P G NG +Guanosine-5’-monophosphate GMP P G NG +O-Phospho-L-Serine 3-phospho-serine P G NG +O-Phospho-D-Serine O-phosphonatooxy-D-serine(2-) P G NG +Phosphate phosphate P G G +Pyrophosphate diphosphate P G NG +Thiophosphate P G NG +Tripolyphosphate triphosphate P G NG +Uridine-5’-monophosphate UMP P G NG +Cytidine-5’-monophosphate CMP P G NG +Phosphoenol Pyruvate phosphoenolpyruvate P G NG +Trimetaphosphate P G NG +Phospho-L-Arginine N(omega)-phospho-L-arginine P G NG +Carbamyl Phosphate carbamoyl phosphate P G NG +O-Phosphoryl-Ethanolamine O-phosphoethanolamine P G NG +D-Glucosamine-6-Phosphate alpha-D-glucosamine 6-phosphate P G G +Phosphocreatine N-phosphocreatine P G NG +Dithiophosphate P G NG +Thymidine-5’-monophosphate thymidine 5'-monophosphate P G NG +Thymidine-3 ’-monophosphate thymidine 3'-monophosphate P G NG +Cysteamine-S-Phosphate cysteamine S-phosphate P G NG +2-Deoxy-D-Glucose 6-Phosphate 2-deoxy-D-glucose 6-phosphate P NG NG +Guanosine-2’-monophosphate guanosine 2'-monophosphate P G NG +D-Glucose-6-Phosphate D-glucose 6-phosphate P G NG +β-Glycerol Phosphate glycerol 2-phosphate(2-) P G NG +Guanosine-3’-monophosphate 3'-GMP P G NG +Phospho-Glycolic Acid 2-phosphoglycolate P G NG +6-Phospho-Gluconic Acid 6-phospho-D-gluconate P G NG +D-Mannose-6-Phosphate D-mannose 6-phosphate P G NG +Cytidine-3’,5’-cyclic monophosphate 3',5'-cyclic CMP P NG NG +Cytidine-2’-monophosphate cytidine 2'-phosphate P G NG +Inositol Hexaphosphate myo-inositol hexakisphosphate P G NG +Guanosine-2’,3’-cyclic monophosphate 2',3'-cyclic GMP P G NG +O-Phospho-L-Tyrosine O(4)-phospho-L-tyrosine P G NG +O-Phospho-L-Threonine O-phospho-L-threonine P G NG +Cytidine-3’-monophosphate P NG NG +D-3-Phospho-Glyceric Acid 3-phosphonato-D-glycerate(3-) P G NG +Triethyl Phosphate P NG NG +Phosphono Acetic Acid P NG NG +Uridine-2’-monophosphate uridine 2'-phosphate P G NG +D-Glucose-1-Phosphate D-glucose 1-phosphate P G NG +Uridine-3’-monophosphate 3'-UMP P G NG +Cytidine-2’ ,3’-cyclic monophosphate 2',3'-cyclic CMP P G NG +2-Aminoethyl Phosphonic Acid P NG NG +Uridine-2’,3’-cyclic monophosphate 2',3'-cyclic UMP P G NG +Adenosine-2’-monophosphate adenosine 2'-phosphate P G NG +Adenosine-3’-monophosphate 3'-AMP P G NG +Adenosine-2’,3’-cyclic monophosphate 2',3'-cyclic AMP P G NG +Hypophosphite P NG NG +Guanosine-3’,5’-cyclic monophosphate 3',5'-cyclic GMP P NG NG +Thymidine 3’,5’-cyclic monophosphate P NG NG +D-Mannose-1-Phosphate D-mannose 1-phosphate P G NG +Urid ine-3’,5’-cyclic monophosphate P NG NG +Methylene Diphosphonic Acid P G NG +Adenosine-3’,5’-cyclic monophosphate 3',5'-cyclic AMP P NG NG +Adenosine-5’-monophosphate AMP P G NG +Sulfate sulphate S G G +L-Cysteine L-cysteine S NG NG +Tetrathionate S NG NG +Thiosulfate thiosulfate S G NG +S-Methyl-L-Cysteine S G NG +Hypotaurine S NG NG +D-Methionine S NG NG +L-Cysteinyl-Glycine L-cysteinylglycine S NG NG +L-Methionine L-methionine S G NG +Glutathione glutathione S G NG +N-Acetyl-D,L-Methionine N(alpha)-acetyl-L-methionine S G NG +L-Methionine Sulfoxide L-Methionine S-oxide S NG NG +Glycyl-L-Methionine Gly-Met S G NG +Taurine tetrathionate S G NG +D-Cysteine S NG NG +Dithiophosphate S G NG +Cystathionine S NG NG +Cysteamine S NG NG +L-Cysteine Sulfinic Acid 3-sulfino-L-alanine S G NG +Thiophosphate S G NG +Lanthionine S NG NG +N-Acetyl-L-Cysteine N-acetyl-L-cysteine S G NG +Thiourea S G NG +1-Thio-β-D-Glucose S G NG +Taurocholic Acid taurocholic acid S NG NG +Butane Sulfonic Acid S G NG +D,L-Lipoamide lipoamide S G NG +L-Djenkolic Acid S NG NG +Methane Sulfonic Acid S NG NG +L-Cysteic Acid L-cysteate S G NG +p-Amino Benzene Sulfonic Acid S NG NG +D,L-Ethionine S NG NG +2-Hydroxyethane Sulfonic Acid 2-hydroxyethane-1-sulfonate S G NG +Tetramethylene Sulfone S NG NG +L-Methionine Sulfone L-Methionine S-oxide S G NG +Ethanol ethanol C G G +D-Raffinose  raffinose C G G +D-Cellobise C G NG +sodium acetate acetate C G G From c7e6ddea20bcdf54eff62697b72bc28e7ec074aa Mon Sep 17 00:00:00 2001 From: FEIRANL Date: Sun, 26 Aug 2018 00:10:09 +0200 Subject: [PATCH 03/27] feat-data:add new rxns and mets Add new rxns and mets to fill the gap between Biolog experiment and model prediction. these new rxns are from metanetx --- .../modelCuration/Biolog_newRxnMatrix.tsv | 571 ++++++++++++++++++ .../Biolog_newRxnMetAnnotation.tsv | 152 +++++ .../modelCuration/Biolog_newRxnProp.tsv | 156 +++++ .../modelCuration/addBiologRxnToGEM.m | 171 ++++++ 4 files changed, 1050 insertions(+) create mode 100644 ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv create mode 100644 ComplementaryData/modelCuration/Biolog_newRxnMetAnnotation.tsv create mode 100644 ComplementaryData/modelCuration/Biolog_newRxnProp.tsv create mode 100644 ComplementaryScripts/modelCuration/addBiologRxnToGEM.m diff --git a/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv b/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv new file mode 100644 index 00000000..ae6f6b32 --- /dev/null +++ b/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv @@ -0,0 +1,571 @@ +rxnID coefficient Metabolite standard name Metabolite_type compartment +MNXR137087 1 Ala-Gln reactant extracellular +MNXR137087 1 H+ reactant extracellular +MNXR137087 1 H+ product cytoplasm +MNXR137087 1 Ala-Gln product cytoplasm +MNXR137087_cv 1 H+ reactant cytoplasm +MNXR137087_cv 1 Ala-Gln reactant cytoplasm +MNXR137087_cv 1 H+ product vacuole +MNXR137087_cv 1 Ala-Gln product vacuole +MNXR123345 1 Ala-Gln reactant vacuole +MNXR123345 1 H2O reactant vacuole +MNXR123345 1 L-glutamine product vacuole +MNXR123345 1 L-alanine product vacuole +MNXR101006 1 Ala-Glu reactant extracellular +MNXR101006 1 H+ reactant extracellular +MNXR101006 1 H+ product cytoplasm +MNXR101006 1 Ala-Glu product cytoplasm +MNXR101006_cv 1 H+ reactant cytoplasm +MNXR101006_cv 1 Ala-Glu reactant cytoplasm +MNXR101006_cv 1 H+ product vacuole +MNXR101006_cv 1 Ala-Glu product vacuole +MNXR101011 1 Ala-Glu reactant vacuole +MNXR101011 1 H2O reactant vacuole +MNXR101011 1 L-glutamate product vacuole +MNXR101011 1 L-alanine product vacuole +Ala-Thr transport via proton symport (excelluar to cytosol) 1 Ala-Thr reactant extracellular +Ala-Thr transport via proton symport (excelluar to cytosol) 1 H+ reactant extracellular +Ala-Thr transport via proton symport (excelluar to cytosol) 1 H+ product cytoplasm +Ala-Thr transport via proton symport (excelluar to cytosol) 1 Ala-Thr product cytoplasm +Ala-Thr transport via proton symport (cytosol to vacuole) 1 H+ reactant cytoplasm +Ala-Thr transport via proton symport (cytosol to vacuole) 1 Ala-Thr reactant cytoplasm +Ala-Thr transport via proton symport (cytosol to vacuole) 1 H+ product vacuole +Ala-Thr transport via proton symport (cytosol to vacuole) 1 Ala-Thr product vacuole +MNXR123349 1 Ala-Thr reactant vacuole +MNXR123349 1 H2O reactant vacuole +MNXR123349 1 L-threonine product vacuole +L-threonine transport, vacuoluar 1 L-threonine reactant cytoplasm +L-threonine transport, vacuoluar 1 L-threonine product vacuole +MNXR123349 1 L-alanine product vacuole +MNXR118741 1 thymidine 3'-monophosphate reactant cytoplasm +MNXR118741 1 H2O reactant cytoplasm +MNXR118741 1 thymidine product cytoplasm +MNXR118741 1 phosphate product cytoplasm +thymidine 3'-monophosphate transport 1 thymidine 3'-monophosphate reactant extracellular +thymidine 3'-monophosphate transport 1 thymidine 3'-monophosphate product cytoplasm +nucleotide-specific phosphatase (thymidine 5'-monophosphate) 1 thymidine 5'-monophosphate reactant cytoplasm +nucleotide-specific phosphatase (thymidine 5'-monophosphate) 1 H2O reactant cytoplasm +nucleotide-specific phosphatase (thymidine 5'-monophosphate) 1 thymidine product cytoplasm +nucleotide-specific phosphatase (thymidine 5'-monophosphate) 1 phosphate product cytoplasm +thymidine 5'-monophosphate transport 1 thymidine 5'-monophosphate reactant extracellular +thymidine 5'-monophosphate transport 1 thymidine 5'-monophosphate product cytoplasm +RHEA:11477 1 glycerol 1-phosphate reactant cytoplasm +RHEA:11477 1 H2O reactant cytoplasm +RHEA:11477 1 glycerol product cytoplasm +RHEA:11477 1 phosphate product cytoplasm +glycerol 1-phosphate transport 1 glycerol 1-phosphate reactant extracellular +glycerol 1-phosphate transport 1 glycerol 1-phosphate product cytoplasm +MNXR137107 1 Ala-His reactant extracellular +MNXR137107 1 H+ reactant extracellular +MNXR137107 1 H+ product cytoplasm +MNXR137107 1 Ala-His product cytoplasm +MNXR137107_cv 1 H+ reactant cytoplasm +MNXR137107_cv 1 Ala-His reactant cytoplasm +MNXR137107_cv 1 H+ product vacuole +MNXR137107_cv 1 Ala-His product vacuole +MNXR123347 1 Ala-His reactant vacuole +MNXR123347 1 H2O reactant vacuole +MNXR123347 1 L-histidine product vacuole +MNXR123347 1 L-alanine product vacuole +Gly-Asn transport via proton symport (excelluar to cytosol) 1 Gly-Asn reactant extracellular +Gly-Asn transport via proton symport (excelluar to cytosol) 1 H+ reactant extracellular +Gly-Asn transport via proton symport (excelluar to cytosol) 1 H+ product cytoplasm +Gly-Asn transport via proton symport (excelluar to cytosol) 1 Gly-Asn product cytoplasm +Gly-Asn transport via proton symport (cytosol to vacuole) 1 H+ reactant cytoplasm +Gly-Asn transport via proton symport (cytosol to vacuole) 1 Gly-Asn reactant cytoplasm +Gly-Asn transport via proton symport (cytosol to vacuole) 1 H+ product vacuole +Gly-Asn transport via proton symport (cytosol to vacuole) 1 Gly-Asn product vacuole +MNXR123350 1 Gly-Asn reactant vacuole +MNXR123350 1 H2O reactant vacuole +MNXR123350 1 L-glycine product vacuole +MNXR123350 1 L-asparagine product vacuole +MNXR137074 1 Gly-Gln reactant extracellular +MNXR137074 1 H+ reactant extracellular +MNXR137074 1 H+ product cytoplasm +MNXR137074 1 Gly-Gln product cytoplasm +MNXR137074_cv 1 H+ reactant cytoplasm +MNXR137074_cv 1 Gly-Gln reactant cytoplasm +MNXR137074_cv 1 H+ product vacuole +MNXR137074_cv 1 Gly-Gln product vacuole +MNXR123351 1 Gly-Gln reactant vacuole +MNXR123351 1 H2O reactant vacuole +MNXR123351 1 L-glycine product vacuole +MNXR123351 1 L-glutamine product vacuole +Gly-Glu transport via proton symport (excelluar to cytosol) 1 Gly-Glu reactant extracellular +Gly-Glu transport via proton symport (excelluar to cytosol) 1 H+ reactant extracellular +Gly-Glu transport via proton symport (excelluar to cytosol) 1 H+ product cytoplasm +Gly-Glu transport via proton symport (excelluar to cytosol) 1 Gly-Glu product cytoplasm +Gly-Glu transport via proton symport (cytosol to vacuole) 1 H+ reactant cytoplasm +Gly-Glu transport via proton symport (cytosol to vacuole) 1 Gly-Glu reactant cytoplasm +Gly-Glu transport via proton symport (cytosol to vacuole) 1 H+ product vacuole +Gly-Glu transport via proton symport (cytosol to vacuole) 1 Gly-Glu product vacuole +MNXR123352 1 Gly-Glu reactant vacuole +MNXR123352 1 H2O reactant vacuole +MNXR123352 1 L-glycine product vacuole +MNXR123352 1 L-glutamate product vacuole +MNXR99852 1 glycerol 2-phosphate(2-) reactant cytoplasm +MNXR99852 1 H2O reactant cytoplasm +MNXR99852 1 glycerol product cytoplasm +MNXR99852 1 phosphate product cytoplasm +MNXR98598 1 glycerol 2-phosphate(2-) reactant extracellular +MNXR98598 1 glycerol 2-phosphate(2-) product cytoplasm +MNXR103332 1 O-phospho-L-threonine reactant cytoplasm +MNXR103332 1 H2O reactant cytoplasm +MNXR103332 1 phosphate product cytoplasm +MNXR103332 1 L-threonine product cytoplasm +MNXR136678 1 H+ reactant extracellular +MNXR136678 1 O-phospho-L-threonine reactant extracellular +MNXR136678 1 O-phospho-L-threonine product cytoplasm +MNXR136678 1 H+ product cytoplasm +MNXR118732 1 guanosine 2'-monophosphate reactant cytoplasm +MNXR118732 1 H2O reactant cytoplasm +MNXR118732 1 guanosine product cytoplasm +MNXR118732 1 phosphate product cytoplasm +Guanosine transport via proton symport 1 H+ reactant extracellular +Guanosine transport via proton symport 1 guanosine 2'-monophosphate reactant extracellular +Guanosine transport via proton symport 1 guanosine 2'-monophosphate product cytoplasm +Guanosine transport via proton symport 1 H+ product cytoplasm +MNXR94936 1 3'-GMP reactant cytoplasm +MNXR94936 1 H2O reactant cytoplasm +MNXR94936 1 guanosine product cytoplasm +MNXR94936 1 phosphate product cytoplasm +Guanosine transport via proton symport(for 3'-GMP) 1 H+ reactant extracellular +Guanosine transport via proton symport(for 3'-GMP) 1 3'-GMP reactant extracellular +Guanosine transport via proton symport(for 3'-GMP) 1 3'-GMP product cytoplasm +Guanosine transport via proton symport(for 3'-GMP) 1 H+ product cytoplasm +MNXR94822 1 H+ reactant extracellular +MNXR94822 1 2-phosphoglycolate reactant extracellular +MNXR94822 1 2-phosphoglycolate product cytoplasm +MNXR94822 1 H+ product cytoplasm +MNXR102543 1 2-phosphoglycolate reactant cytoplasm +MNXR102543 1 H2O reactant cytoplasm +MNXR102543 1 phosphate product cytoplasm +MNXR102543 1 glycolate product cytoplasm +MNXR118734 1 cysteamine S-phosphate reactant cytoplasm +MNXR118734 1 H2O reactant cytoplasm +MNXR118734 1 cysteamine product cytoplasm +MNXR137130 1 H+ reactant extracellular +MNXR137130 1 cysteamine reactant extracellular +MNXR137130 1 cysteamine product cytoplasm +Exchange reaction, cysteamine 1 cysteamine reactant extracellular +MNXR137130 1 H+ product cytoplasm +MNXR118734 1 phosphate product cytoplasm +cysteamine S-phosphate transport via proton symport 1 cysteamine S-phosphate reactant extracellular +cysteamine S-phosphate transport via proton symport 1 cysteamine S-phosphate product cytoplasm +MNXR107528 1 cysteamine reactant cytoplasm +MNXR107528 1 oxygen reactant cytoplasm +MNXR107528 1 hypotaurine product cytoplasm +MNXR107528 1 H+ product cytoplasm +MNXR107116 1 hypotaurine reactant cytoplasm +MNXR107116 1 H2O reactant cytoplasm +MNXR107116 1 NAD reactant cytoplasm +MNXR107116 1 taurine product cytoplasm +MNXR107116 1 H+ product cytoplasm +MNXR107116 1 NADH product cytoplasm +MNXR103265 1 H2O reactant cytoplasm +MNXR103265 1 O-phosphonatooxy-D-serine(2-) reactant cytoplasm +MNXR103265 1 D-Serine product cytoplasm +MNXR103265 1 phosphate product cytoplasm +MNXR103244 1 O-phosphonatooxy-D-serine(2-) reactant extracellular +MNXR103244 1 H+ reactant extracellular +MNXR103244 1 H+ product cytoplasm +MNXR103244 1 O-phosphonatooxy-D-serine(2-) product cytoplasm +MNXR103594 1 2-oxobutanoate reactant cytoplasm +MNXR103594 1 L-glutamate reactant cytoplasm +MNXR103594 1 2-aminobutanoate product cytoplasm +MNXR103594 1 2-oxoglutarate product cytoplasm +2-aminobutyrate transport 1 H+ reactant extracellular +2-aminobutyrate transport 1 2-aminobutanoate reactant extracellular +2-aminobutyrate transport 1 2-aminobutanoate product cytoplasm +2-aminobutyrate transport 1 H+ product cytoplasm +MNXR118730 1 uridine 2'-phosphate reactant cytoplasm +MNXR118730 1 H2O reactant cytoplasm +MNXR118730 1 uridine product cytoplasm +MNXR118730 1 phosphate product cytoplasm +MNXR136675 1 H+ reactant extracellular +MNXR136675 1 uridine 2'-phosphate reactant extracellular +MNXR136675 1 uridine 2'-phosphate product cytoplasm +MNXR136675 1 H+ product cytoplasm +MNXR94932 1 3'-UMP reactant cytoplasm +MNXR94932 1 H2O reactant cytoplasm +MNXR94932 1 uridine product cytoplasm +MNXR94932 1 phosphate product cytoplasm +MNXR94982 1 H+ reactant extracellular +MNXR94982 1 3'-UMP reactant extracellular +MNXR94982 1 3'-UMP product cytoplasm +MNXR94982 1 H+ product cytoplasm +MNXR137072 1 Gly-Met reactant extracellular +MNXR137072 1 H+ reactant extracellular +MNXR137072 1 H+ product cytoplasm +MNXR137072 1 Gly-Met product cytoplasm +MNXR137072_cv 1 H+ reactant cytoplasm +MNXR137072_cv 1 Gly-Met reactant cytoplasm +MNXR137072_cv 1 H+ product vacuole +MNXR137072_cv 1 Gly-Met product vacuole +MNXR123343 1 Gly-Met reactant vacuole +MNXR123343 1 H2O reactant vacuole +MNXR123343 1 L-methionine product vacuole +MNXR123343 1 L-glycine product vacuole +MNXR111061 1 N-phosphocreatine reactant cytoplasm +MNXR111061 1 creatinine product cytoplasm +MNXR111061 1 phosphate product cytoplasm +N-phosphocreatine transport 1 H+ reactant extracellular +N-phosphocreatine transport 1 N-phosphocreatine reactant extracellular +N-phosphocreatine transport 1 N-phosphocreatine product cytoplasm +N-phosphocreatine transport 1 H+ product cytoplasm +creatinine transport 1 H+ reactant extracellular +creatinine transport 1 creatinine reactant extracellular +creatinine transport 1 creatinine product cytoplasm +creatinine transport 1 H+ product cytoplasm +MNXR95943 1 H+ reactant cytoplasm +MNXR95943 1 N(omega)-phospho-L-arginine reactant cytoplasm +MNXR95943 1 ADP reactant cytoplasm +MNXR95943 1 ATP product cytoplasm +MNXR95943 1 L-arginine product cytoplasm +MNXR95947 1 H+ reactant extracellular +MNXR95947 1 N(omega)-phospho-L-arginine reactant extracellular +MNXR95947 1 N(omega)-phospho-L-arginine product cytoplasm +MNXR95947 1 H+ product cytoplasm +MNXR117325 1 2',3'-cyclic GMP reactant cytoplasm +MNXR117325 1 H2O reactant cytoplasm +MNXR117325 1 H+ product cytoplasm +MNXR117325 1 guanosine 2'-monophosphate product cytoplasm +MNXR94721 1 2',3'-cyclic GMP reactant extracellular +MNXR94721 1 2',3'-cyclic GMP product cytoplasm +MNXR104998 1 H2O reactant cytoplasm +MNXR104998 1 O(4)-phospho-L-tyrosine reactant cytoplasm +MNXR104998 1 L-tyrosine product cytoplasm +MNXR104998 1 phosphate product cytoplasm +MNXR137095 1 H+ reactant extracellular +MNXR137095 1 O(4)-phospho-L-tyrosine reactant extracellular +MNXR137095 1 O(4)-phospho-L-tyrosine product cytoplasm +MNXR137095 1 H+ product cytoplasm +MNXR103069 1 triphosphate reactant cytoplasm +MNXR103069 1 H2O reactant cytoplasm +MNXR103069 1 phosphate product cytoplasm +MNXR103069 1 diphosphate product cytoplasm +MNXR135003 1 H+ reactant extracellular +MNXR135003 1 triphosphate reactant extracellular +MNXR135003 1 triphosphate product cytoplasm +MNXR135003 1 H+ product cytoplasm +MNXR118731 1 cytidine 2'-phosphate reactant cytoplasm +MNXR118731 1 H2O reactant cytoplasm +MNXR118731 1 cytidine product cytoplasm +MNXR118731 1 phosphate product cytoplasm +MNXR135010 1 H+ reactant extracellular +MNXR135010 1 cytidine 2'-phosphate reactant extracellular +MNXR135010 1 cytidine 2'-phosphate product cytoplasm +MNXR135010 1 H+ product cytoplasm +MNXR117327 1 2',3'-cyclic UMP reactant cytoplasm +MNXR117327 1 H2O reactant cytoplasm +MNXR117327 1 uridine 2'-phosphate product cytoplasm +MNXR117327 1 H+ product cytoplasm +MNXR136674 1 H+ reactant extracellular +MNXR136674 1 2',3'-cyclic UMP reactant extracellular +MNXR136674 1 2',3'-cyclic UMP product cytoplasm +MNXR136674 1 H+ product cytoplasm +MNXR123155 1 3-sulfino-L-alanine reactant cytoplasm +MNXR123155 1 H2O reactant cytoplasm +MNXR123155 1 L-alanine product cytoplasm +MNXR123155 1 sulphite product cytoplasm +MNXR137086 1 H+ reactant extracellular +MNXR137086 1 3-sulfino-L-alanine reactant extracellular +MNXR137086 1 3-sulfino-L-alanine product cytoplasm +MNXR137086 1 H+ product cytoplasm +MNXR94935 1 3'-AMP reactant cytoplasm +MNXR94935 1 H2O reactant cytoplasm +MNXR94935 1 adenosine product cytoplasm +MNXR94935 1 phosphate product cytoplasm +MNXR94857 1 3'-AMP reactant extracellular +MNXR94857 1 3'-AMP product cytoplasm +MNXR130717 1 6-O-alpha-D-glucopyranosyl-D-fructofuranose reactant cytoplasm +MNXR130717 1 H2O reactant cytoplasm +MNXR130717 1 D-fructose product cytoplasm +MNXR130717 1 D-glucose product cytoplasm +MNXR102339 1 H+ reactant extracellular +MNXR102339 1 6-O-alpha-D-glucopyranosyl-D-fructofuranose reactant extracellular +MNXR102339 1 6-O-alpha-D-glucopyranosyl-D-fructofuranose product cytoplasm +MNXR102339 1 H+ product cytoplasm +MNXR103637 1 N-acetyl-L-cysteine reactant cytoplasm +MNXR103637 1 coenzyme A reactant cytoplasm +MNXR103637 1 H+ reactant cytoplasm +MNXR103637 1 acetyl-CoA product cytoplasm +MNXR103637 1 L-cysteine product cytoplasm +MNXR137052 1 H+ reactant extracellular +MNXR137052 1 N-acetyl-L-cysteine reactant extracellular +MNXR137052 1 N-acetyl-L-cysteine product cytoplasm +MNXR137052 1 H+ product cytoplasm +MNXR106345 1 tetrathionate reactant cytoplasm +MNXR106345 2 ferricytochrome c reactant mitochondrion +MNXR106345 2 thiosulfate product cytoplasm +MNXR106345 2 ferrocytochrome c product mitochondrion +MNXR104796 1 tetrathionate reactant extracellular +MNXR104796 1 tetrathionate product cytoplasm +L-methionine transport, vacuoluar 1 L-methionine reactant cytoplasm +L-methionine transport, vacuoluar 1 L-methionine product vacuole +MNXR99485 1 2-hydroxyethane-1-sulfonate reactant cytoplasm +MNXR99485 1 FMNH2 reactant cytoplasm +MNXR99485 1 oxygen reactant cytoplasm +MNXR99485 1 H+ product cytoplasm +MNXR99485 1 sulphite product cytoplasm +MNXR99485 1 H2O product cytoplasm +MNXR99485 1 FMN product cytoplasm +MNXR99485 1 glycolaldehyde product cytoplasm +MNXR137058 1 H+ reactant extracellular +MNXR137058 1 2-hydroxyethane-1-sulfonate reactant extracellular +MNXR137058 1 2-hydroxyethane-1-sulfonate product cytoplasm +MNXR137058 1 H+ product cytoplasm +MNXR95065 1 H+ reactant cytoplasm +MNXR95065 1 NADPH reactant cytoplasm +MNXR95065 1 5-dehydro-D-gluconate reactant cytoplasm +MNXR95065 1 D-gluconate product cytoplasm +MNXR95065 1 NADP(+) product cytoplasm +MNXR95066 1 H+ reactant extracellular +MNXR95066 1 5-dehydro-D-gluconate reactant extracellular +MNXR95066 1 5-dehydro-D-gluconate product cytoplasm +MNXR95066 1 H+ product cytoplasm +MNXR137135 1 Ala-Asp reactant extracellular +MNXR137135 1 H+ reactant extracellular +MNXR137135 1 H+ product cytoplasm +MNXR137135 1 Ala-Asp product cytoplasm +MNXR137135_cv 1 H+ reactant cytoplasm +MNXR137135_cv 1 Ala-Asp reactant cytoplasm +MNXR137135_cv 1 H+ product vacuole +MNXR137135_cv 1 Ala-Asp product vacuole +MNXR123344 1 Ala-Asp reactant vacuole +MNXR123344 1 H2O reactant vacuole +MNXR123344 1 L-alanine product vacuole +MNXR123344 1 L-aspartate product vacuole +MNXR96247 1 methyl alpha-D-glucopyranoside reactant cytoplasm +MNXR96247 1 H2O reactant cytoplasm +MNXR96247 1 D-glucose product cytoplasm +MNXR96247 1 methanol product cytoplasm +MNXR101464 1 methanol reactant cytoplasm +MNXR101464 1 methanol product extracellular +MNXR98748 1 methanol reactant extracellular +MNXR137048 1 H+ reactant extracellular +MNXR137048 1 methyl alpha-D-glucopyranoside reactant extracellular +MNXR137048 1 methyl alpha-D-glucopyranoside product cytoplasm +MNXR137048 1 H+ product cytoplasm +MNXR117326 1 2',3'-cyclic CMP reactant cytoplasm +MNXR117326 1 H2O reactant cytoplasm +MNXR117326 1 cytidine 2'-phosphate product cytoplasm +MNXR117326 1 H+ product cytoplasm +MNXR136673 1 H+ reactant extracellular +MNXR136673 1 2',3'-cyclic CMP reactant extracellular +MNXR136673 1 2',3'-cyclic CMP product cytoplasm +MNXR136673 1 H+ product cytoplasm +MNXR107830 1 D-tagatose reactant cytoplasm +MNXR107830 1 ATP reactant cytoplasm +MNXR107830 1 ADP product cytoplasm +MNXR107830 1 D-tagatofuranose 6-phosphate product cytoplasm +MNXR107830 1 H+ product cytoplasm +R11623 1 D-tagatofuranose 6-phosphate reactant cytoplasm +R11623 1 D-fructose 6-phosphate product cytoplasm +MNXR104707 1 D-tagatose reactant extracellular +MNXR104707 1 D-tagatose product cytoplasm +MNXR130716 1 turanose reactant extracellular +MNXR130716 1 H2O reactant extracellular +MNXR130716 1 D-fructose product extracellular +MNXR130716 1 D-glucose product extracellular +MNXR95136 1 acetoacetate reactant cytoplasm +MNXR95136 1 ATP reactant cytoplasm +MNXR95136 1 coenzyme A reactant cytoplasm +MNXR95136 1 AMP product cytoplasm +MNXR95136 1 diphosphate product cytoplasm +MNXR95136 1 acetoacetyl-CoA product cytoplasm +MNXR95208 1 acetoacetate reactant extracellular +MNXR95208 1 acetoacetate product cytoplasm +MNXR103709 1 N(alpha)-acetyl-L-methionine reactant cytoplasm +MNXR103709 1 H2O reactant cytoplasm +MNXR103709 1 acetate product cytoplasm +MNXR103709 1 L-methionine product cytoplasm +MNXR137089 1 H+ reactant extracellular +MNXR137089 1 N(alpha)-acetyl-L-methionine reactant extracellular +MNXR137089 1 N(alpha)-acetyl-L-methionine product cytoplasm +MNXR137089 1 H+ product cytoplasm +MNXR106549 1 3-oxalomalate(3-) reactant cytoplasm +MNXR106549 1 oxaloacetate product cytoplasm +MNXR106549 1 glyoxylate product cytoplasm +MNXR137067 1 H+ reactant extracellular +MNXR137067 1 3-oxalomalate(3-) reactant extracellular +MNXR137067 1 3-oxalomalate(3-) product cytoplasm +MNXR137067 1 H+ product cytoplasm +MNXR111236 1 L-cysteate reactant cytoplasm +MNXR111236 1 H2O reactant cytoplasm +MNXR111236 1 pyruvate product cytoplasm +MNXR111236 1 ammonium product cytoplasm +MNXR111236 1 sulphite product cytoplasm +MNXR124424 1 H+ reactant extracellular +MNXR124424 1 L-cysteate reactant extracellular +MNXR124424 1 L-cysteate product cytoplasm +MNXR124424 1 H+ product cytoplasm +MNXR101619 1 alpha-maltotriose reactant extracellular +MNXR101619 1 H2O reactant extracellular +MNXR101619 1 maltose product extracellular +MNXR101619 1 D-glucose product extracellular +MNXR94824 1 H+ reactant extracellular +MNXR94824 1 2-phospho-D-glyceric acid reactant extracellular +MNXR94824 1 2-phospho-D-glyceric acid product cytoplasm +MNXR94824 1 H+ product cytoplasm +MNXR94973 1 H+ reactant extracellular +MNXR94973 1 3-phosphonato-D-glycerate(3-) reactant extracellular +MNXR94973 1 3-phosphonato-D-glycerate(3-) product cytoplasm +MNXR94973 1 H+ product cytoplasm +Met-Ala transport via proton symport (excelluar to cytosol) 1 Met-Ala reactant extracellular +Met-Ala transport via proton symport (excelluar to cytosol) 1 H+ reactant extracellular +Met-Ala transport via proton symport (excelluar to cytosol) 1 H+ product cytoplasm +Met-Ala transport via proton symport (excelluar to cytosol) 1 Met-Ala product cytoplasm +Met-Ala transport via proton symport (cytosol to vacuole) 1 H+ reactant cytoplasm +Met-Ala transport via proton symport (cytosol to vacuole) 1 Met-Ala reactant cytoplasm +Met-Ala transport via proton symport (cytosol to vacuole) 1 H+ product vacuole +Met-Ala transport via proton symport (cytosol to vacuole) 1 Met-Ala product vacuole +MNXR99849 1 D-glucose 1-phosphate reactant extracellular +MNXR99849 1 D-glucose 1-phosphate product cytoplasm +MNXR96488 1 carbamoyl phosphate reactant extracellular +MNXR96488 1 carbamoyl phosphate product cytoplasm +MNXR103245 1 3-phospho-serine reactant extracellular +MNXR103245 1 H+ reactant extracellular +MNXR103245 1 H+ product cytoplasm +MNXR103245 1 3-phospho-serine product cytoplasm +MNXR100385 1 GMP reactant extracellular +MNXR100385 1 H+ reactant extracellular +MNXR100385 1 H+ product cytoplasm +MNXR100385 1 GMP product cytoplasm +MNXR101585 1 myo-inositol hexakisphosphate reactant extracellular +MNXR101585 1 myo-inositol hexakisphosphate product cytoplasm +MNXR98531 1 D-glucose 6-phosphate reactant extracellular +MNXR98531 1 D-glucose 6-phosphate product cytoplasm +MNXR105127 1 UMP reactant extracellular +MNXR105127 1 UMP product cytoplasm +MNXR102493 1 phosphoenolpyruvate reactant extracellular +MNXR102493 1 H+ reactant extracellular +MNXR102493 1 H+ product cytoplasm +MNXR102493 1 phosphoenolpyruvate product cytoplasm +MNXR101385 1 D-mannose 6-phosphate reactant extracellular +MNXR101385 1 D-mannose 6-phosphate product cytoplasm +MNXR135002 1 O-phosphoethanolamine reactant extracellular +MNXR135002 1 H+ reactant extracellular +MNXR135002 1 H+ product cytoplasm +MNXR135002 1 O-phosphoethanolamine product cytoplasm +MNXR95102 1 6-phospho-D-gluconate reactant extracellular +MNXR95102 1 H+ reactant extracellular +MNXR95102 1 H+ product cytoplasm +MNXR95102 1 6-phospho-D-gluconate product cytoplasm +MNXR101377 1 D-mannose 1-phosphate reactant extracellular +MNXR101377 1 H+ reactant extracellular +MNXR101377 1 H+ product cytoplasm +MNXR101377 1 D-mannose 1-phosphate product cytoplasm +MNXR136667 1 diphosphate reactant extracellular +MNXR136667 2 H+ reactant extracellular +MNXR136667 2 H+ product cytoplasm +MNXR136667 1 diphosphate product cytoplasm +MNXR96703 1 choline phosphate reactant extracellular +MNXR96703 1 choline phosphate product cytoplasm +MNXR104966 1 thiosulfate reactant extracellular +MNXR104966 1 thiosulfate product cytoplasm +MNXR95831 1 AMP reactant extracellular +MNXR95831 1 H+ reactant extracellular +MNXR95831 1 H+ product cytoplasm +MNXR95831 1 AMP product cytoplasm +MNXR94718 1 2',3'-cyclic AMP reactant extracellular +MNXR94718 1 2',3'-cyclic AMP product cytoplasm +MNXR135007 1 adenosine 2'-phosphate reactant extracellular +MNXR135007 1 H+ reactant extracellular +MNXR135007 1 H+ product cytoplasm +MNXR135007 1 adenosine 2'-phosphate product cytoplasm +MNXR96805 1 CMP reactant extracellular +MNXR96805 1 H+ reactant extracellular +MNXR96805 1 H+ product cytoplasm +MNXR96805 1 CMP product cytoplasm +MNXR100035 1 D-Glucosamine reactant extracellular +MNXR100035 1 D-Glucosamine product cytoplasm +2-deoxy-D-ribose transport 1 2-deoxy-D-ribose reactant extracellular +2-deoxy-D-ribose transport 1 2-deoxy-D-ribose product cytoplasm +MNXR96737 1 L-citrulline reactant extracellular +MNXR96737 1 H+ reactant extracellular +MNXR96737 1 H+ product cytoplasm +MNXR96737 1 L-citrulline product cytoplasm +MNXR97367 1 glycerone reactant extracellular +MNXR97367 1 glycerone product cytoplasm +Ala-Leu transport via proton symport (excelluar to cytosol) 1 Ala-Leu reactant extracellular +Ala-Leu transport via proton symport (excelluar to cytosol) 1 H+ reactant extracellular +Ala-Leu transport via proton symport (excelluar to cytosol) 1 H+ product cytoplasm +Ala-Leu transport via proton symport (excelluar to cytosol) 1 Ala-Leu product cytoplasm +Ala-Leu transport via proton symport (cytosol to vacuole) 1 H+ reactant cytoplasm +Ala-Leu transport via proton symport (cytosol to vacuole) 1 Ala-Leu reactant cytoplasm +Ala-Leu transport via proton symport (cytosol to vacuole) 1 H+ product vacuole +Ala-Leu transport via proton symport (cytosol to vacuole) 1 Ala-Leu product vacuole +MNXR137133 1 Ala-Gly reactant extracellular +MNXR137133 1 H+ reactant extracellular +MNXR137133 1 H+ product cytoplasm +MNXR137133 1 Ala-Gly product cytoplasm +MNXR137133_cv 1 H+ reactant cytoplasm +MNXR137133_cv 1 Ala-Gly reactant cytoplasm +MNXR137133_cv 1 H+ product vacuole +MNXR137133_cv 1 Ala-Gly product vacuole +N-acetyl-L-glutamate transport 1 N-acetyl-L-glutamate reactant extracellular +N-acetyl-L-glutamate transport 1 N-acetyl-L-glutamate product cytoplasm +N-acetyl-L-glutamate transport, mitochondrion 1 N-acetyl-L-glutamate reactant cytoplasm +N-acetyl-L-glutamate transport, mitochondrion 1 N-acetyl-L-glutamate product mitochondrion +MNXR137094 1 lipoamide reactant extracellular +MNXR137094 1 H+ reactant extracellular +MNXR137094 1 H+ product cytoplasm +MNXR137094 1 lipoamide product cytoplasm +MNXR101483 1 L-Methionine S-oxide reactant extracellular +MNXR101483 1 L-Methionine S-oxide product cytoplasm +Hydrogen sulfide oxidation 1 hydrogen sulfide reactant cytoplasm +Hydrogen sulfide oxidation 2 oxygen reactant cytoplasm +Hydrogen sulfide oxidation 1 H+ product cytoplasm +Hydrogen sulfide oxidation 1 sulphate product cytoplasm +MNXR95704 1 H+ reactant cytoplasm +MNXR95704 1 L-alanine reactant cytoplasm +MNXR95704 1 L-alanine product vacuole +MNXR95704 1 H+ product vacuole +MNXR100368 1 H+ reactant cytoplasm +MNXR100368 1 L-glycine reactant cytoplasm +MNXR100368 1 L-glycine product vacuole +MNXR100368 1 H+ product vacuole +MNXR104382 1 O-succinyl-L-homoserine reactant cytoplasm +MNXR104382 1 hydrogen sulfide reactant cytoplasm +MNXR104382 1 L-homocysteine product cytoplasm +MNXR104382 1 succinate product cytoplasm +MNXR94843 1 oxygen reactant cytoplasm +MNXR94843 1 3-(4-hydroxyphenyl)pyruvate reactant cytoplasm +MNXR94843 1 homogentisate product cytoplasm +MNXR94843 1 carbon dioxide product cytoplasm +MNXR100628 1 homogentisate reactant cytoplasm +MNXR100628 1 oxygen reactant cytoplasm +MNXR100628 1 4-maleylacetoacetate product cytoplasm +MNXR100628 1 H+ product cytoplasm +MNXR101325 1 4-maleylacetoacetate reactant cytoplasm +MNXR101325 1 4-fumarylacetoacetate product cytoplasm +MNXR99706 1 4-fumarylacetoacetate reactant cytoplasm +MNXR99706 1 H2O reactant cytoplasm +MNXR99706 1 fumarate product cytoplasm +MNXR99706 1 acetoacetate product cytoplasm +MNXR99706 1 H+ product cytoplasm +MNXR95187 1 L-arabinitol reactant cytoplasm +MNXR95187 1 NAD reactant cytoplasm +MNXR95187 1 H+ product cytoplasm +MNXR95187 1 NADH product cytoplasm +MNXR95187 1 L-xylulose product cytoplasm +MNXR105265 1 L-xylulose reactant cytoplasm +MNXR105265 1 NADPH reactant cytoplasm +MNXR105265 1 H+ reactant cytoplasm +MNXR105265 1 xylitol product cytoplasm +MNXR105265 1 NADP(+) product cytoplasm +arabinose reductase (D-arabinose) 1 D-arabinose reactant cytoplasm +arabinose reductase (D-arabinose) 1 NADPH reactant cytoplasm +arabinose reductase (D-arabinose) 1 H+ reactant cytoplasm +arabinose reductase (D-arabinose) 1 D-arabinitol product cytoplasm +arabinose reductase (D-arabinose) 1 NADP(+) product cytoplasm +MNXR95188 1 D-arabinitol reactant cytoplasm +MNXR95188 1 NAD reactant cytoplasm +MNXR95188 1 H+ product cytoplasm +MNXR95188 1 NADH product cytoplasm +MNXR95188 1 D-xylulose product cytoplasm +MNXR118733 1 adenosine 2'-phosphate reactant cytoplasm +MNXR118733 1 H2O reactant cytoplasm +MNXR118733 1 adenosine product cytoplasm +MNXR118733 1 phosphate product cytoplasm diff --git a/ComplementaryData/modelCuration/Biolog_newRxnMetAnnotation.tsv b/ComplementaryData/modelCuration/Biolog_newRxnMetAnnotation.tsv new file mode 100644 index 00000000..12926410 --- /dev/null +++ b/ComplementaryData/modelCuration/Biolog_newRxnMetAnnotation.tsv @@ -0,0 +1,152 @@ +NewMetName Charged formula Charge compartment KEGG ID CHEBI ID Remark +Ala-Gln [extracellular] C8H15N3O4 0 extracellular CHEBI:73788 MNXM40495 +Ala-Gln [cytoplasm] C8H15N3O4 0 cytoplasm CHEBI:73788 MNXM40495 +Ala-Gln [vacuole] C8H15N3O4 0 vacuole CHEBI:73788 MNXM40495 +Ala-Glu [extracellular] C8H13N2O5 -1 extracellular C20958 CHEBI:61396 MNXM4026 +Ala-Glu [cytoplasm] C8H13N2O5 -1 cytoplasm C20958 CHEBI:61396 MNXM4026 +Ala-Glu [vacuole] C8H13N2O5 -1 vacuole C20958 CHEBI:61396 MNXM4026 +Ala-Thr [extracellular] C7H14N2O4 0 extracellular CHEBI:73762 MNXM40497 +Ala-Thr [cytoplasm] C7H14N2O4 0 cytoplasm CHEBI:73762 MNXM40497 +Ala-Thr [vacuole] C7H14N2O4 0 vacuole CHEBI:73762 MNXM40497 +L-threonine [vacuole] C4H9NO3 0 vacuole C00188 CHEBI:16857 MNXM142 +thymidine 3'-monophosphate [cytoplasm] C10H13N2O8P -2 cytoplasm CHEBI:77843 MNXM87165 +thymidine 3'-monophosphate [extracellular] C10H13N2O8P -2 extracellular CHEBI:77843 MNXM87165 +thymidine 5'-monophosphate [cytoplasm] C10H13N2O8P -2 cytoplasm CHEBI:15245 MNXM87167 +thymidine 5'-monophosphate [extracellular] C10H13N2O8P -2 extracellular CHEBI:15245 MNXM87167 +glycerol 1-phosphate [cytoplasm] C3H7O6P -2 cytoplasm C03189 CHEBI:231935 MNXM682 +glycerol 1-phosphate [extracellular] C3H7O6P -2 extracellular C03189 CHEBI:231935 MNXM682 +Ala-His [extracellular] C9H14N4O3 0 extracellular CHEBI:73771 MNXM40496 +Ala-His [cytoplasm] C9H14N4O3 0 cytoplasm CHEBI:73771 MNXM40496 +Ala-His [vacuole] C9H14N4O3 0 vacuole CHEBI:73771 MNXM40496 +Gly-Asn [extracellular] C6H11N3O4 0 extracellular CHEBI:73888 MNXM55268 +Gly-Asn [cytoplasm] C6H11N3O4 0 cytoplasm CHEBI:73888 MNXM55268 +Gly-Asn [vacuole] C6H11N3O4 0 vacuole CHEBI:73888 MNXM55268 +Gly-Gln [extracellular] C7H13N3O4 0 extracellular CHEBI:73898 MNXM55276 +Gly-Gln [cytoplasm] C7H13N3O4 0 cytoplasm CHEBI:73898 MNXM55276 +Gly-Gln [vacuole] C7H13N3O4 0 vacuole CHEBI:73898 MNXM55276 +Gly-Glu [extracellular] C7H11N2O5 -1 extracellular CHEBI:73784 MNXM55454 +Gly-Glu [cytoplasm] C7H11N2O5 -1 cytoplasm CHEBI:73784 MNXM55454 +Gly-Glu [vacuole] C7H11N2O5 -1 vacuole CHEBI:73784 MNXM55454 +glycerol 2-phosphate(2-) [cytoplasm] C3H7O6P -2 cytoplasm C02979 CHEBI:58083 MNXM2527 +glycerol 2-phosphate(2-) [extracellular] C3H7O6P -2 extracellular C02979 CHEBI:58083 MNXM2527 +O-phospho-L-threonine [cytoplasm] C4H8NO6P -2 cytoplasm C12147 CHEBI:58675 MNXM1492 +O-phospho-L-threonine [extracellular] C4H8NO6P -2 extracellular C12147 CHEBI:58675 MNXM1492 +guanosine 2'-monophosphate [cytoplasm] C10H12N5O8P -2 cytoplasm CHEBI:74604 MNXM18285 +guanosine 2'-monophosphate [extracellular] C10H12N5O8P -2 extracellular CHEBI:74604 MNXM18285 +3'-GMP [cytoplasm] C10H12N5O8P -2 cytoplasm C06193 CHEBI:60732 MNXM2183 +3'-GMP [extracellular] C10H12N5O8P -2 extracellular C06193 CHEBI:60732 MNXM2183 +2-phosphoglycolate [extracellular] C2H2O6P -3 extracellular C00988 CHEBI:58033 MNXM2074 +2-phosphoglycolate [cytoplasm] C2H2O6P -3 cytoplasm C00988 CHEBI:58033 MNXM2074 +cysteamine S-phosphate [cytoplasm] C2H7NO3PS -1 cytoplasm CHEBI:74631 MNXM48297 +cysteamine [cytoplasm] C2H8NS 1 cytoplasm C01678 CHEBI:58029 MNXM1226 +cysteamine [extracellular] C2H8NS 1 extracellular C01678 CHEBI:58029 MNXM1226 +cysteamine S-phosphate [extracellular] C2H7NO3PS -1 extracellular CHEBI:74631 MNXM48297 +hypotaurine [cytoplasm] C2H7NO2S 0 cytoplasm C00519 CHEBI:16668 MNXM726 +O-phosphonatooxy-D-serine(2-) [cytoplasm] C3H6NO6P -2 cytoplasm C02532 CHEBI:58680 MNXM4752 +O-phosphonatooxy-D-serine(2-) [extracellular] C3H6NO6P -2 extracellular C02532 CHEBI:58680 MNXM4752 +2-aminobutanoate [cytoplasm] C4H9NO2 0 cytoplasm CHEBI:35621 MNXM15850 +2-aminobutanoate [extracellular] C4H9NO2 0 extracellular CHEBI:35621 MNXM15850 +uridine 2'-phosphate [cytoplasm] C9H11N2O9P -2 cytoplasm C03031 CHEBI:77802 MNXM13238 +uridine 2'-phosphate [extracellular] C9H11N2O9P -2 extracellular C03031 CHEBI:77802 MNXM13238 +3'-UMP [cytoplasm] C9H11N2O9P -2 cytoplasm C01368 CHEBI:60784 MNXM2184 +3'-UMP [extracellular] C9H11N2O9P -2 extracellular C01368 CHEBI:60784 MNXM2184 +Gly-Met [extracellular] C7H14N2O3S 0 extracellular CHEBI:74393 MNXM55287 +Gly-Met [cytoplasm] C7H14N2O3S 0 cytoplasm CHEBI:74393 MNXM55287 +Gly-Met [vacuole] C7H14N2O3S 0 vacuole CHEBI:74393 MNXM55287 +N-phosphocreatine [cytoplasm] C4H8N3O5P -2 cytoplasm CHEBI:58092 MNXM819 +creatinine [cytoplasm] C4H7N3O 0 cytoplasm C00791 CHEBI:16737 MNXM1470 +N-phosphocreatine [extracellular] C4H8N3O5P -2 extracellular CHEBI:58092 MNXM819 +creatinine [extracellular] C4H7N3O 0 extracellular C00791 CHEBI:16737 MNXM1470 +N(omega)-phospho-L-arginine [cytoplasm] C6H14N4O5P -1 cytoplasm C05945 CHEBI:58477 MNXM3663 +N(omega)-phospho-L-arginine [extracellular] C6H14N4O5P -1 extracellular C05945 CHEBI:58477 MNXM3663 +2',3'-cyclic GMP [cytoplasm] C10H11N5O7P -1 cytoplasm C06194 CHEBI:60837 MNXM3149 +2',3'-cyclic GMP [extracellular] C10H11N5O7P -1 extracellular C06194 CHEBI:60837 MNXM3149 +O(4)-phospho-L-tyrosine [cytoplasm] C9H10NO6P -2 cytoplasm C06501 CHEBI:62338 MNXM3323 +O(4)-phospho-L-tyrosine [extracellular] C9H10NO6P -2 extracellular C06501 CHEBI:62338 MNXM3323 +triphosphate [cytoplasm] O10P3 -5 cytoplasm C00536 CHEBI:18036 MNXM332 +triphosphate [extracellular] O10P3 -5 extracellular C00536 CHEBI:18036 MNXM332 +cytidine 2'-phosphate [cytoplasm] C9H12N3O8P -2 cytoplasm C03104 CHEBI:77766 MNXM11237 +cytidine 2'-phosphate [extracellular] C9H12N3O8P -2 extracellular C03104 CHEBI:77766 MNXM11237 +2',3'-cyclic UMP [cytoplasm] C9H10N2O8P -1 cytoplasm C02355 CHEBI:60873 MNXM3150 +2',3'-cyclic UMP [extracellular] C9H10N2O8P -1 extracellular C02355 CHEBI:60873 MNXM3150 +3-sulfino-L-alanine [cytoplasm] C3H6NO4S -1 cytoplasm C00606 CHEBI:61085 MNXM498 +3-sulfino-L-alanine [extracellular] C3H6NO4S -1 extracellular C00606 CHEBI:61085 MNXM498 +3'-AMP [cytoplasm] C10H12N5O7P -2 cytoplasm C01367 CHEBI:60880 MNXM1985 +3'-AMP [extracellular] C10H12N5O7P -2 extracellular C01367 CHEBI:60880 MNXM1985 +6-O-alpha-D-glucopyranosyl-D-fructofuranose [cytoplasm] C12H22O11 0 cytoplasm C01742 CHEBI:18394 MNXM3518 +6-O-alpha-D-glucopyranosyl-D-fructofuranose [extracellular] C12H22O11 0 extracellular C01742 CHEBI:18394 MNXM3518 +N-acetyl-L-cysteine [cytoplasm] C5H8NO3S -1 cytoplasm C06809 CHEBI:78236 MNXM98606 +N-acetyl-L-cysteine [extracellular] C5H8NO3S -1 extracellular C06809 CHEBI:78236 MNXM98606 +tetrathionate [cytoplasm] O6S4 -2 cytoplasm C02084 CHEBI:15226 MNXM1781 +thiosulfate [cytoplasm] HO3S2 -1 cytoplasm C00320 CHEBI:33542 MNXM323 +tetrathionate [extracellular] O6S4 -2 extracellular C02084 CHEBI:15226 MNXM1781 +glycyl-L-methionine [extracellular] C7H14N2O3S 0 extracellular CHEBI:74393 MNXM55287 +glycyl-L-methionine [cytoplasm] C7H14N2O3S 0 cytoplasm CHEBI:74393 MNXM55287 +glycyl-L-methionine [vacuole] C7H14N2O3S 0 vacuole CHEBI:74393 MNXM55287 +2-hydroxyethane-1-sulfonate [cytoplasm] C2H5O4S -1 cytoplasm C05123 CHEBI:61904 MNXM1630 +2-hydroxyethane-1-sulfonate [extracellular] C2H5O4S -1 extracellular C05123 CHEBI:61904 MNXM1630 +5-dehydro-D-gluconate [cytoplasm] C6H9O7 -1 cytoplasm C01062 CHEBI:58143 MNXM963 +5-dehydro-D-gluconate [extracellular] C6H9O7 -1 extracellular C01062 CHEBI:58143 MNXM963 +Ala-Asp [extracellular] C7H11N2O5 -1 extracellular CHEBI:74363 MNXM40494 +Ala-Asp [cytoplasm] C7H11N2O5 -1 cytoplasm CHEBI:74363 MNXM40494 +Ala-Asp [vacuole] C7H11N2O5 -1 vacuole CHEBI:74363 MNXM40494 +methyl alpha-D-glucopyranoside [cytoplasm] C7H14O6 0 cytoplasm CHEBI:320061 MNXM61741 +methanol [cytoplasm] CH4O 0 cytoplasm C00132 CHEBI:17790 MNXM157 +methanol [extracellular] CH4O 0 extracellular C00132 CHEBI:17790 MNXM157 +methyl alpha-D-glucopyranoside [extracellular] C7H14O6 0 extracellular CHEBI:320061 MNXM61741 +2',3'-cyclic CMP [cytoplasm] C9H11N3O7P -1 cytoplasm C02354 CHEBI:60877 MNXM3148 +2',3'-cyclic CMP [extracellular] C9H11N3O7P -1 extracellular C02354 CHEBI:60877 MNXM3148 +D-tagatose [cytoplasm] C6H12O6 0 cytoplasm C00795 CHEBI:4249 MNXM92401 +D-tagatofuranose 6-phosphate [cytoplasm] C6H11O9P -2 cytoplasm C01097 CHEBI:58695 MNXM795 +D-tagatose [extracellular] C6H12O6 0 extracellular C00795 CHEBI:4249 MNXM92401 +turanose [extracellular] C12H22O11 0 extracellular C19636 CHEBI:32528 MNXM161984 +acetoacetate [cytoplasm] C4H5O3 -1 cytoplasm C00164 CHEBI:13705 MNXM154 +acetoacetate [extracellular] C4H5O3 -1 extracellular C00164 CHEBI:13705 MNXM154 +N(alpha)-acetyl-L-methionine [cytoplasm] C7H12NO3S -1 cytoplasm C02712 CHEBI:132957 MNXM7576 +N(alpha)-acetyl-L-methionine [extracellular] C7H12NO3S -1 extracellular C02712 CHEBI:132957 MNXM7576 +3-oxalomalate(3-) [cytoplasm] C6H3O8 -3 cytoplasm C01990 CHEBI:15593 MNXM3850 +3-oxalomalate(3-) [extracellular] C6H3O8 -3 extracellular C01990 CHEBI:15593 MNXM3850 +L-cysteate [cytoplasm] C3H6NO5S -1 cytoplasm C00506 CHEBI:58090 MNXM713 +L-cysteate [extracellular] C3H6NO5S -1 extracellular C00506 CHEBI:58090 MNXM713 +alpha-maltotriose [extracellular] C18H32O16 0 extracellular C01835 CHEBI:61993 MNXM468 +2-phospho-D-glyceric acid [extracellular] C3H4O7P -3 extracellular C00631 CHEBI:58289 MNXM275 +3-phosphonato-D-glycerate(3-) [extracellular] C3H4O7P -3 extracellular C00197 CHEBI:58272 MNXM126 +Met-Ala [extracellular] C8H16N2O3S 0 extracellular CHEBI:73610 MNXM61647 +Met-Ala [cytoplasm] C8H16N2O3S 0 cytoplasm CHEBI:73610 MNXM61647 +D-glucose 1-phosphate [extracellular] C6H11O9P -2 extracellular C00103 CHEBI:57629 MNXM89588 +carbamoyl phosphate [extracellular] CH2NO5P -2 extracellular C00169 CHEBI:58228 MNXM138 +3-phospho-serine [extracellular] C3H6NO6P -2 extracellular C01005 CHEBI:57524 MNXM379 +GMP [extracellular] C10H12N5O8P -2 extracellular C00144 CHEBI:58115 MNXM113 +myo-inositol hexakisphosphate [extracellular] C6H6O24P6 -12 extracellular C01204 CHEBI:58130 MNXM491 +D-glucose 6-phosphate [extracellular] C6H11O9P -2 extracellular C00092 CHEBI:61548 MNXM160 +UMP [extracellular] C9H11N2O9P -2 extracellular C00105 CHEBI:57865 MNXM80 +phosphoenolpyruvate [extracellular] C3H2O6P -3 extracellular C00074 CHEBI:58702 MNXM73 +D-mannose 6-phosphate [extracellular] C6H11O9P -2 extracellular C00275 CHEBI:58735 MNXM427 +O-phosphoethanolamine [extracellular] C2H7NO4P -1 extracellular C00346 CHEBI:58190 MNXM187 +6-phospho-D-gluconate [extracellular] C6H10O10P -3 extracellular C00345 CHEBI:58759 MNXM325 +D-mannose 1-phosphate [extracellular] C6H11O9P -2 extracellular C00636 CHEBI:58409 MNXM721 +diphosphate [extracellular] HO7P2 -3 extracellular C00013 CHEBI:33019 MNXM11 +choline phosphate [extracellular] C5H13NO4P -1 extracellular C00588 CHEBI:295975 MNXM229 +thiosulfate [extracellular] HO3S2 -1 extracellular C00320 CHEBI:33542 MNXM323 +AMP [extracellular] C10H12N5O7P -2 extracellular C00020 CHEBI:456215 MNXM14 +2',3'-cyclic AMP [extracellular] C10H11N5O6P -1 extracellular C02353 CHEBI:60879 MNXM2598 +adenosine 2'-phosphate [extracellular] C10H12N5O7P -2 extracellular C00946 CHEBI:77740 MNXM7028 +CMP [extracellular] C9H12N3O8P -2 extracellular C00055 CHEBI:60377 MNXM31 +D-Glucosamine [extracellular] C6H14NO5 1 extracellular C00329 CHEBI:58723 MNXM533 +2-deoxy-D-ribose [extracellular] C5H10O4 0 extracellular C08347 CHEBI:28816 MNXM2474 +L-citrulline [extracellular] C6H13N3O3 0 extracellular C00327 CHEBI:16349 MNXM211 +glycerone [extracellular] C3H6O3 0 extracellular C00184 CHEBI:16016 MNXM460 +Ala-Leu [extracellular] C9H18N2O3 0 extracellular CHEBI:73770 MNXM15786 +Ala-Leu [cytoplasm] C9H18N2O3 0 cytoplasm CHEBI:73770 MNXM15786 +Ala-Gly [extracellular] C5H10N2O3 0 extracellular CHEBI:73757 MNXM15783 +Ala-Gly [cytoplasm] C5H10N2O3 0 cytoplasm CHEBI:73757 MNXM15783 +N-acetyl-L-glutamate [extracellular] C7H9NO5 -2 extracellular C00624 CHEBI:44337 MNXM730 +N-acetyl-L-glutamate [cytoplasm] C7H9NO5 -2 cytoplasm C00624 CHEBI:44337 MNXM730 +lipoamide [extracellular] C8H15NOS2 0 extracellular C00248 CHEBI:17460 MNXM1024 +lipoamide [cytoplasm] C8H15NOS2 0 cytoplasm C00248 CHEBI:17460 MNXM1024 +L-Methionine S-oxide [extracellular] C5H11NO3S 0 extracellular C02989 CHEBI:17016 MNXM2246 +homogentisate [cytoplasm] C8H7O4 -1 cytoplasm C00544 CHEBI:16169 MNXM345 +4-maleylacetoacetate [cytoplasm] C8H6O6 -2 cytoplasm C01036 CHEBI:17105 MNXM691 +4-fumarylacetoacetate [cytoplasm] C8H6O6 -2 cytoplasm C01061 CHEBI:18034 MNXM708 +L-xylulose [cytoplasm] C5H10O5 0 cytoplasm C00310 CHEBI:17140 MNXM597 +D-arabinitol [cytoplasm] C5H12O5 0 cytoplasm C01904 CHEBI:18333 MNXM1018 diff --git a/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv b/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv new file mode 100644 index 00000000..0128f240 --- /dev/null +++ b/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv @@ -0,0 +1,156 @@ +rxnID rev GPR rxn_name_seed EC rxnID_kegg Source;reason +MNXR98598 1 Exchange rxns for glyc bigg:EX_glyc2p_e;glycerol 2-phosphate(2-)_P Source +MNXR99852 0 Glycerol-2-phosphate phosphohydrolase 3.1.3.19 R01043 rhea:13105;glycerol 2-phosphate(2-)_P Source +MNXR136678 1 L-Threonine phosphate transport in via proton symport seed:rxn11407;O-phospho-L-threonine_P Source +MNXR103332 0 acid phosphatase / phosphotransferase 3.1.3.- rhea:30579;O-phospho-L-threonine_P Source +MNXR118732 0 alkaline phosphatase 3.1.3.- metacyc:RXN-14512;guanosine 2'-monophosphate_P Source +Guanosine transport via proton symport 1 Guanosine transport via proton symport NA;guanosine 2'-monophosphate_P Source +MNXR94936 0 Guanosine 3'-phosphate phosphohydrolase 3.1.3.6 R02148 rhea:27862;3'-GMP_P Source +Guanosine transport via proton symport(for 3'-GMP) 1 Guanosine transport via proton symport(for 3'-GMP) NA;3'-GMP_P Source +MNXR94822 1 2-Phosphoglycolate transport in/out via proton symport seed:rxn05473;2-phosphoglycolate_P Source +MNXR102543 0 2-phosphoglycolate phosphohydrolase 3.1.3.18 R01334 rhea:14369;2-phosphoglycolate_P Source +MNXR118734 0 alkaline phosphatase 3.1.3.- rhea:37251;cysteamine S-phosphate_P Source +cysteamine S-phosphate transport via proton symport 1 cysteamine S-phosphate transport via proton symport NA;cysteamine S-phosphate_P Source +MNXR107528 0 Cysteamine:oxygen oxidoreductase 1.13.11.19 R02467 rhea:14409;cysteamine S-phosphate_P Source +MNXR107116 0 hypotaurine:NAD+ oxidoreductase 1.8.1.3 R01681 rhea:17385;cysteamine S-phosphate_P Source +MNXR103594 1 2-aminobutanoate:2-oxoglutarate aminotransferase 2.6.1.42 R10991 bigg:RE2034C;2-aminobutanoate_N Source +2-aminobutyrate transport 1 2-aminobutyrate transport NA;2-aminobutanoate_N Source +MNXR118730 0 alkaline phosphatase 3.1.3.- rhea:37355;uridine 2'-phosphate_P Source +MNXR136675 1 Uridine 2'-phosphate transport in via proton symport seed:rxn11403;uridine 2'-phosphate_P Source +MNXR94932 0 Uridine 3'-monophosphate phosphohydrolase 3.1.3.6 R01877 rhea:27890;3'-UMP_P Source +MNXR94982 1 3'-UMP transport in via proton symport seed:rxn05480;3'-UMP_P Source +MNXR137072 1 Gly-Met transport via proton symport seed:rxn12552;Gly-Met_N Source +MNXR123343 0 dipeptidase 3.4.13.18 rhea:37323;Gly-Met_N Source +MNXR111061 0 R07420 R07420 seed:rxn05129;N-phosphocreatine_P Source +N-phosphocreatine transport 1 N-phosphocreatine transport NA;N-phosphocreatine_P Source +creatinine transport 1 creatinine transport NA;N-phosphocreatine_P Source +MNXR95943 1 ATP:L-arginine Nomega-phosphotransferase 2.7.3.3 R00554 rhea:22940;N(omega)-phospho-L-arginine_P Source +MNXR95947 1 L-arginine phosphate transport in/out via proton symport seed:rxn05502;N(omega)-phospho-L-arginine_P Source +MNXR104998 0 acid phosphatase / phosphotransferase rhea:30863;O(4)-phospho-L-tyrosine_P Source +MNXR135003 1 Tripolyphosphate transport in via proton symport seed:rxn05717;triphosphate_P Source +MNXR118731 0 alkaline phosphatase 3.1.3.- rhea:37351;cytidine 2'-phosphate_P Source +MNXR135010 1 Cytidine- 2'- Monophosphate transport in via proton symport seed:rxn05724;cytidine 2'-phosphate_P Source +MNXR117327 0 cyclic phosphodiesterase 3.1.4.37 rhea:37239;2',3'-cyclic UMP_P Source +MNXR136674 1 2',3'-Cyclic UMP transport in via proton symport seed:rxn11402;2',3'-cyclic UMP_P Source +MNXR123155 0 3-Sulfino-L-alanine 4-carboxy-lyase 3.13.1.- R00863 rhea:28278;3-sulfino-L-alanine_S Source +MNXR137086 1 3-Sulfino-L-alanine transport via proton antiport seed:rxn12567;3-sulfino-L-alanine_S Source +MNXR94935 0 adenosine 3'-phosphate phosphohydrolase 3.1.3.6 R01562 rhea:27898;3'-AMP_P Source +MNXR94857 1 3AMP transport via diffusion (extracellular to periplasm) seed:rxn07973;3'-AMP_P Source +MNXR130717 0 α-glucosidase 3.2.1.20 sabiork:11700;6-O-alpha-D-glucopyranosyl-D-fructofuranose_C Source +MNXR102339 1 Palatinose transport in via proton symport seed:rxn05629;6-O-alpha-D-glucopyranosyl-D-fructofuranose_C Source +MNXR103637 1 Amino-Acid N-Acetyltransferase bigg:RE2223M;N-acetyl-L-cysteine_S Source +MNXR137052 1 Acetylcysteine transport via proton symport seed:rxn12528;N-acetyl-L-cysteine_S Source +MNXR106345 1 thiosulfate:ferricytochrome-c oxidoreductase 1.8.2.2 R00029;tetrathionate_S Source +MNXR104796 1 etrathionate transport via diffusion bigg:TETtex;tetrathionate_S Source +MNXR95065 0 D-Gluconate:NADP+ 5-oxidoreductase 1.1.1.-;1.1.1.69 R01740 rhea:23936;5-dehydro-D-gluconate_C Source +MNXR95066 1 5-Dehydro-D-gluconate transport via proton symport rhea:28819;5-dehydro-D-gluconate_C Source +MNXR123344 0 dipeptidase 3.4.13.18 rhea:37267;Ala-Asp_N Source +MNXR137135 1 ala-L-asp-L transport via proton symport seed:rxn12628;Ala-Asp_N Source +MNXR117326 0 cyclic phosphodiesterase 3.1.4.37 rhea:41956;cytidine 2'-phosphate_P Source +MNXR136673 1 2',3'-Cyclic CMP transport in via proton symport seed:rxn11401;2',3'-cyclic CMP_P Source +MNXR96247 1 beta-glucosidase (methyl-alpha-D-glucoside) 3.2.1.21 seed:rxn09978;methyl alpha-D-glucopyranoside_C Source +MNXR101464 0 Methanol diffusion rhea:34871;methyl alpha-D-glucopyranoside_C Source +MNXR137048 1 alpha-Methyl-D-glucoside transport via proton symport seed:rxn12524;methyl alpha-D-glucopyranoside_C Source +MNXR107830 0 ATP:D-tagatose 6-phosphotransferase 2.7.1.101 seed:rxn02094;D-tagatose_C Source +R11623 1 D-tagatose 6-phosphate 4-epimerase NA;D-tagatose_C Source +MNXR104707 1 D-tagatose uptake via diffusion bigg:TAGAT_Dt;D-tagatose_C Source +MNXR95136 0 Acetoacetate:CoA ligase (AMP-forming) 6.2.1.16 R01357 rhea:16117;acetoacetate_C Source +MNXR103709 1 N-Acyl-Aliphatic-L-Amino Acid Amidohydrolase 3.5.1.14 bigg:RE2640C;N(alpha)-acetyl-L-methionine_S Source +MNXR137087 1 Ala-Gln transport via proton symport seed:rxn12568;Ala-Gln_N Source +MNXR101006_cv 1 L-alanyl-L-glutamate transport in via proton symport rhea:35131;Ala-Glu_N Source +MNXR101619 0 Maltodextrin glucosidase (maltotriose) 3.2.1.20 seed:rxn05746;alpha-maltotriose_C Source +Ala-Thr transport via proton symport (cytosol to vacuole) 1 Ala-Thr transport via proton symport NA;Ala-Thr_N Source +Ala-Thr transport via proton symport (excelluar to cytosol) 1 Ala-Thr transport via proton symport NA;Ala-Thr_N Source +MNXR103069 0 ( YHR201C or YDR452W ) Triphosphate phosphohydrolase 3.6.1.25 R00138 rhea:14157;triphosphate_P Source +Gly-Asn transport via proton symport (excelluar to cytosol) 1 Gly-Asn transport via proton symport NA;Gly-Asn_N Source +glycerol 1-phosphate transport 1 glycerol 1-phosphate transport NA;glycerol 1-phosphate_P Source +MNXR103244 1 D-O-Phosphoserine transport in/out via proton symport seed:rxn05639;O-phosphonatooxy-D-serine(2-)_P Source +MNXR103265 1 D-O-Phosphoserine phosphohydrolase 3.1.3.3 R02853 rhea:24873;O-phosphonatooxy-D-serine(2-)_P Source +MNXR101006 1 L-alanyl-L-glutamate transport in via proton symport rhea:35131;Ala-Glu_N Source +MNXR101011 0 L-alanyl-gamma-L-glutamate peptidase 3.4.13.18 rhea:29335;Ala-Glu_N Source +MNXR106549 1 3-oxalomalate glyoxylate-lyase (oxaloacetate-forming) 4.1.3.13 R00477 rhea:22032;3-oxalomalate(3-)_C Source +MNXR111236 0 L-cysteate bisulfite-lyase (deaminating) 4.4.1.25 R07634 rhea:13441;L-cysteate_S Source +MNXR117325 0 cyclic phosphodiesterase 3.1.4.37 rhea:37211;guanosine 2'-monophosphate_P Source +MNXR118741 0 deoxynucleotide 3'-phosphatase 3.1.3.34 rhea:37247;thymidine 3'-monophosphate_P Source +MNXR123345 0 cytosol nonspecific dipeptidase 3.4.13.18 rhea:37275;Ala-Gln_N Source +MNXR123347 0 Cytosol non-specific dipeptidase 3.4.13.18 rhea:37283;Ala-His_N Source +MNXR123349 0 Cytosol non-specific dipeptidase 3.4.13.18 rhea:37299;Ala-Thr_N Source +MNXR123350 0 Cytosol non-specific dipeptidase 3.4.13.18 rhea:37307;Gly-Asn_N Source +MNXR123351 0 Cytosol non-specific dipeptidase 3.4.13.18 rhea:37315;Gly-Gln_N Source +MNXR124424 1 L-Cysteate transport via proton symport seed:rxn12602;L-cysteate_S Source +MNXR130716 1 alpha-glucosidase 3.2.1.20 sabiork:11699;turanose_C Source +MNXR137058 1 2-Hydroxyethanesulfonate transport via proton symport seed:rxn12535;2-hydroxyethane-1-sulfonate_S Source +MNXR137067 1 3-Oxalomalate transport via proton symport seed:rxn12545;3-oxalomalate(3-)_C Source +MNXR137072_cv 1 Gly-Met transport via proton symport seed:rxn12552;Gly-Met_N Source +MNXR137074 1 Gly-Gln transport via proton symport seed:rxn12555;Gly-Gln_N Source +MNXR137074_cv 1 Gly-Gln transport via proton symport seed:rxn12555;Gly-Gln_N Source +MNXR137087_cv 1 Ala-Gln transport via proton symport seed:rxn12568;Ala-Gln_N Source +MNXR137089 1 N-Acetylmethionine transport via proton symport seed:rxn12570;N(alpha)-acetyl-L-methionine_S Source +MNXR137095 1 Phosphotyrosine transport via proton symport seed:rxn12580;O(4)-phospho-L-tyrosine_P Source +MNXR137107 1 Ala-His transport via proton symport seed:rxn12594;Ala-His_N Source +MNXR137107_cv 1 Ala-His transport via proton symport seed:rxn12594;Ala-His_N Source +MNXR137135_cv 1 ala-L-asp-L transport via proton symport seed:rxn12628;Ala-Asp_N Source +MNXR99485 0 FMNH2-dependent alkanesulfonate monooxygenase 1.14.14.5 rhea:29715;2-hydroxyethane-1-sulfonate_S Source +thymidine 3'-monophosphate transport 1 thymidine 3-monophosphate transport NA;thymidine 3'-monophosphate_P Source +thymidine 5'-monophosphate transport 1 thymidine 5-monophosphate transport NA;thymidine 5'-monophosphate_P Source +RHEA:11477 0 ( YIL053W or YER062C ) glycerol-1-phosphate phosphohydrolase R08658 NA;glycerol 1-phosphate_P Source +nucleotide-specific phosphatase (thymidine 5'-monophosphate) 0 nucleotide-specific phosphatase (thymidine 5'-monophosphate) NA;thymidine 5'-monophosphate_P Source +Gly-Glu transport via proton symport (excelluar to cytosol) 1 Gly-Glu transport via proton symport (excelluar to cytosol) NA;Gly-Glu_N Source +Gly-Glu transport via proton symport (cytosol to vacuole) 1 Gly-Glu transport via proton symport (cytosol to vacuole) NA;Gly-Glu_N Source +MNXR123352 0 cytosol nonspecific dipeptidase 3.4.13.18 rhea:36463;Gly-Glu_N Source +L-methionine transport, vacuoluar 1 L-methionine transport, vacuoluar NA;L-methionine_N Source +L-threonine transport, vacuoluar 1 L-threonine transport, vacuoluar NA;L-threonine_N Source +Exchange reaction, cysteamine 1 Exchange reaction, cysteamine NA;cysteamine S-phosphate_P Source +MNXR94721 1 23cGMP transport via diffusion (extracellular to periplasm) seed:rxn07927;2',3'-cyclic GMP_P Source +MNXR94824 1 D-Glycerate 2-phosphate transport in/out via proton symport seed:rxn05474;2-phospho-D-glyceric acid_P Source +MNXR94973 1 3-Phospho-D-glycerate transport in/out via proton symport seed:rxn05479;3-phosphonato-D-glycerate(3-)_P Source +MNXR99849 1 D-glucose 1-phosphate transport via diffusion seed:rxn08545;D-glucose 1-phosphate_P Source +MNXR96488 1 carbamoyl phosphate nuclear transport via diffusion seed:rxn09823;carbamoyl phosphate_P Source +Met-Ala transport via proton symport (excelluar to cytosol) 1 Met-Ala transport via proton symport (excelluar to cytosol) NA;Met-Ala_N Source +Met-Ala transport via proton symport (cytosol to vacuole) 1 Met-Ala transport via proton symport (cytosol to vacuole) NA;Met-Ala_N Source +MNXR103245 1 O-Phospho-L-serine transport in via proton symport seed:rxn05640;3-phospho-serine_P Source +MNXR100385 1 GMP transport via proton symport seed:rxn05471;GMP_P Source +MNXR101585 1 myo-inositol phosphate transport via diffusion (extracellular to periplasm) seed:rxn08925;myo-inositol hexakisphosphate_P Source +MNXR98531 1 Exchange rxns for g6p bigg:EX_g6p_e;D-glucose 6-phosphate_P Source +MNXR105127 1 UMP transport rhea:27926;UMP_P Source +MNXR102493 1 Phosphoenolpyruvate transport in via proton symport seed:rxn05630;phosphoenolpyruvate_P Source +MNXR101385 1 Mannose 6-phosphate transport via diffusion (extracellular to periplasm) seed:rxn08880;D-mannose 6-phosphate_P Source +MNXR135002 1 O-Phosphoryl-Ethanolamine transport in via proton symport seed:rxn05716;O-phosphoethanolamine_P Source +MNXR95102 1 6-Phospho-D-gluconate transport in/out via proton symport seed:rxn05482;6-phospho-D-gluconate_P Source +MNXR101377 1 MAN1P transport in/out via proton symport seed:rxn05609;D-mannose 1-phosphate_P Source +MNXR136667 1 Pyrophosphate transport in via proton symport seed:rxn11395;diphosphate_P Source +MNXR96703 1 Choline phosphate intracellular transport bigg:CHOLPtg;choline phosphate_P Source +MNXR104966 1 thiosulfate transport rhea:32807;thiosulfate_S Source +MNXR95831 1 AMP transport in/out via proton symport seed:rxn05497;AMP_P Source +MNXR94718 1 23cAMP transport via diffusion (extracellular to periplasm) seed:rxn07925;2',3'-cyclic AMP_P Source +MNXR135007 1 Adenosine- 2'-Monophosphate transport in via proton symport seed:rxn05721;CMP_P Source +MNXR96805 1 CMP transport in/out via proton symport seed:rxn05525;CMP_P Source +MNXR100035 1 D-glucosamine transport via diffusion (extracellular to periplasm) seed:rxn08593;D-Glucosamine_C Source +2-deoxy-D-ribose transport 1 2-deoxy-D-ribose transport NA;2-deoxy-D-ribose_C Source +MNXR96737 1 L-Citrulline transport in via proton symport seed:rxn05674;L-citrulline_N Source +MNXR97367 1 Dihydroxyacetone transport via facilitated diffusion seed:rxn05532;glycerone_C Source +Ala-Leu transport via proton symport (excelluar to cytosol) 1 Ala-Leu transport via proton symport (excelluar to cytosol) NA;Ala-Leu_N Source +Ala-Leu transport via proton symport (cytosol to vacuole) 1 Ala-Leu transport via proton symport (cytosol to vacuole) NA;Ala-Leu_N Source +MNXR137133 1 L-alanylglycine transport via proton antiport seed:rxn12625;Ala-Gly_N Source +MNXR137133_cv 1 L-alanylglycine transport via proton antiport seed:rxn12625;Ala-Gly_N Source +N-acetyl-L-glutamate transport 1 N-acetyl-L-glutamate transport NA;N-acetyl-L-glutamate_N Source +N-acetyl-L-glutamate transport, mitochondrion 1 N-acetyl-L-glutamate transport NA;N-acetyl-L-glutamate_N Source +MNXR137094 1 Lipoamide transport via proton symport seed:rxn12577;lipoamide_S Source +MNXR101483 1 L-methionine S-oxide diffusion (extracellular) seed:rxn08915;L-Methionine S-oxide_S Source +Gly-Asn transport via proton symport (cytosol to vacuole) 1 Gly-Asn transport via proton symport NA;Gly-Asn_N Source +MNXR137130 1 Cysteamine transport via proton antiport seed:rxn12622;cysteamine S-phosphate_P Source +Hydrogen sulfide oxidation 0 Hydrogen sulfide oxidation NA;general sulfur metabolism_S Source +MNXR95704 1 L-alanine transport in via proton symport rhea:29443;L-alanine_N Source +MNXR100368 1 Glycine mitochondrial transport rhea:28899;L-glycine_N Source +MNXR104382 1 ( YJR130C or YLL058W or YML082W ) O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) 2.5.1.-;2.5.1.48 R01288 rhea:27826;L-methionine_N Source +MNXR94843 0 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) 1.13.11.27 R02521 rhea:16189;L-tyrosine_N Source +MNXR100628 0 Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) 1.13.11.5 R02519 rhea:15449;L-tyrosine_N Source +MNXR101325 0 4-Maleylacetoacetate cis-trans-isomerase 5.2.1.2 R03181 rhea:14817;L-tyrosine_N Source +MNXR99706 0 4-fumarylacetoacetate fumarylhydrolase 3.7.1.2 R01364 rhea:10244;L-tyrosine_N Source +MNXR95187 0 L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming) 1.1.1.12 R01903 rhea:16381;D-arabinose_C Source +MNXR105265 1 Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) 1.1.1.10 R01904 rhea:17025;D-arabinose_C Source +arabinose reductase (D-arabinose) 0 arabinose reductase (D-arabinose) NA;D-arabinose_C Source +MNXR95188 0 D-arabinitol:NAT 4-oxidoreductase 1.1.1.11 R05604 rhea:17921;D-arabinose_C Source +MNXR95208 1 Acetoacetate transport via diffusion rhea:29751;acetoacetate_C Source +MNXR98748 1 Exchange rxns for meoh bigg:EX_meoh_e;methyl alpha-D-glucopyranoside_C Source +MNXR118733 0 alkaline phosphatase 3.1.3.- rhea:37343;adenosine 2'-phosphate_P Source diff --git a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m new file mode 100644 index 00000000..48ea5ea6 --- /dev/null +++ b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m @@ -0,0 +1,171 @@ +% This Function is for adding Biolog related metabolites/reactions into model. +% Add rxns and metabolites based on Biolog results, see +% Biolog_substrate_type.tsv for substrates that can be ultilized +% Input: model, Biolog_substrate_type.tsv,Biolog_newRxnProp.tsv,Biolog_newRxnMet.tsv. +% As for the reference of new genes and reactions related, please find detailed information in the /ComplementaryData/experiment/Biolog_experiment.tsv +% NOTE: changeGeneAssociation.m is a function from cobra +% Extract model info from .tsv format. +% Before run the codes below, the file should be manually editted. +% COBRA required. +% New reaction should be in .tsv format. +% +% Feiran Li +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%newreaction: +% Load model +cd .. +model = loadYeastModel; + +fid = fopen('../ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv'); +newreaction = textscan(fid,'%s %s %s %s %s','Delimiter','\t','HeaderLines',1); +matrix.rxnIDs = newreaction{1}; +matrix.metcoef = cellfun(@str2num, newreaction{2}); +matrix.metIDs = newreaction{3}; +matrix.mettype = newreaction{4}; +matrix.metcompartments = newreaction{5}; +fclose(fid); +%rev and GPR +fid = fopen('../ComplementaryData/modelCuration/Biolog_newRxnProp.tsv','r'); +rev = textscan(fid,'%s %s %s %s %s %s %s','Delimiter','\t','HeaderLines',1); +newrxn.ID = rev{1}; +newrxn.Rev = cellfun(@str2num, rev{2}); +newrxn.GPR = rev{3}; +newrxn.rxnNames = rev{4}; +newrxn.rxnECNumbers = rev{5}; +newrxn.rxnKEGGID = rev{6}; +newrxn.rxnNotes = rev{7}; +fclose(fid); + +%change coefficient +%matrix.metcoef_temp = cellfun(@str2num, matrix.metcoef); +for i=1:length(matrix.rxnIDs) + if strcmp(matrix.mettype(i),'reactant') + matrix.metcoef(i) = matrix.metcoef(i)*-1 + %matrix.metcoef_temp(i) = matrix.metcoef_temp(i)*-1 + end +end +%matrix.metcoef = num2cell(matrix.metcoef_temp); + + +%change compatments +CONValldata = cat(2,model.compNames,model.comps); +lbracket = ' [' ;% space +llbracket = '['; +rbrackets = ']'; +space = ' '; +[m, n] = size(CONValldata); +for i = 1:m + aa = CONValldata(i,1); + aa = char(aa); + for j=1:length(matrix.rxnIDs) + bb = matrix.metcompartments(j,1); + bb = char(bb); + if strcmp(bb,aa) + matrix.Newcomps(j,1) = CONValldata(i,2); + end + end +end +for i=1:length(matrix.rxnIDs) + matrix.metnames(i) = strcat(matrix.metIDs(i),lbracket,matrix.metcompartments(i),rbrackets); + matrix.Newcomps(i) = strcat(llbracket,matrix.Newcomps(i),rbrackets); +end + + + +%mapping mets to model.metnames, get s_ index for new mets +cd modelCuration/ +for j = 1:length(matrix.metnames) + [~,metindex] = ismember(matrix.metnames(j),model.metNames); + if metindex ~= 0 + matrix.mets(j) = model.mets(metindex); + elseif metindex == 0 + newID = getNewIndex(model.mets); + matrix.mets(j) = strcat('s_',newID,matrix.Newcomps(j)); + model = addMetabolite(model,char(matrix.mets(j)), ... + 'metName',matrix.metnames(j)); + end +end + + +% add met annotation +fid = fopen('../../ComplementaryData/modelCuration/Biolog_newRxnMetAnnotation.tsv'); +newmet_annot = textscan(fid,'%s %s %s %s %s %s %s','Delimiter','\t','HeaderLines',1); +newmet.metNames = newmet_annot{1}; +newmet.metFormulas = newmet_annot{2}; +newmet.metCharges = cellfun(@str2num, newmet_annot{3}); +newmet.metKEGGID = newmet_annot{5}; +newmet.metChEBIID = newmet_annot{6}; +newmet.metNotes = newmet_annot{7}; +fclose(fid); + +for i = 1:length(newmet.metNames) + [~,metID] = ismember(newmet.metNames(i),model.metNames); + if metID ~= 0 + model.metFormulas{metID} = newmet.metFormulas{i}; + model.metCharges(metID) = newmet.metCharges(i); + model.metKEGGID{metID} = newmet.metKEGGID{i}; + model.metChEBIID{metID} = newmet.metChEBIID{i}; + model.metNotes{metID} = newmet.metNotes{i}; + end +end + +%add new reactions according to rev ID. Met Coef need to be in the column, +%not a row. Coef should be double, which was converted at the import +%section. + EnergyResults = {}; +MassChargeresults = {}; +RedoxResults = {}; +for i = 1:length(newrxn.ID) + cd ../otherchanges + newID = getNewIndex(model.rxns); + cd ../modelCuration + j = find(strcmp(matrix.rxnIDs,newrxn.ID{i})); + Met = matrix.mets(j); + Coef = transpose(matrix.metcoef(j)); + model = addReaction(model,... + ['r_' newID],... + 'reactionName', newrxn.ID{i},... + 'metaboliteList',Met,... + 'stoichCoeffList',Coef,... + 'reversible',newrxn.Rev(i,1),... + 'geneRule',newrxn.GPR{i},... + 'checkDuplicate',1); + [EnergyResults,RedoxResults] = CheckEnergyProduction(model,{['r_' newID]},EnergyResults,RedoxResults); + [MassChargeresults] = CheckBalanceforSce(model,{['r_' newID]},MassChargeresults); +end + +% add gene standard name for new genes +fid = fopen('../../ComplementaryData/databases/SGDgeneNames.tsv'); +yeast_gene_annotation = textscan(fid,'%s %s','Delimiter','\t','HeaderLines',1); +fclose(fid); + +geneIndex = zeros(1,1); +for i = 1: length(model.genes) + geneIndex = strcmp(yeast_gene_annotation{1}, model.genes{i}); + if sum(geneIndex) == 1 && ~isempty(yeast_gene_annotation{2}{geneIndex}) + model.geneNames{i} = yeast_gene_annotation{2}{geneIndex}; + else + model.geneNames{i} = model.genes{i}; + end +end + +% Add protein name for genes +for i = 1:length(model.genes) + model.proteins{i} = strcat('COBRAProtein',num2str(i)); +end + +%add rxn annotation +for i = 1:length(newrxn.ID) + [~,rxnID] = ismember(newrxn.ID(i),model.rxnNames); + if rxnID ~= 0 + model.rxnNames{rxnID} = newrxn.rxnNames{i}; + model.rxnECNumbers(rxnID) = newrxn.rxnECNumbers(i); + model.rxnKEGGID(rxnID) = newrxn.rxnKEGGID(i); + end +end + +% Save model: +model = rmfield(model,'grRules'); +cd .. +saveYeastModel(model) +cd modelCuration + From cc1868d86a69884cdb3307a8a108a4f6e88e7c42 Mon Sep 17 00:00:00 2001 From: FEIRANL Date: Sun, 26 Aug 2018 00:15:16 +0200 Subject: [PATCH 04/27] feat-met:add new mets into the model add new mets into the model --- ModelFiles/dependencies.txt | 4 +- ModelFiles/xml/yeastGEM.xml | 3508 +++++++++++++++++++++++++++++++++++ ModelFiles/yml/yeastGEM.yml | 1288 +++++++++++++ README.md | 4 +- 4 files changed, 4800 insertions(+), 4 deletions(-) diff --git a/ModelFiles/dependencies.txt b/ModelFiles/dependencies.txt index 92ff2a9b..c83ee6a1 100644 --- a/ModelFiles/dependencies.txt +++ b/ModelFiles/dependencies.txt @@ -1,7 +1,7 @@ -MATLAB 9.4.0.813654 (R2018a) +MATLAB 9.1.0.441655 (R2016b) libSBML 5.17.0 RAVEN_toolbox 2.0.0 -COBRA_toolbox commit 6a4b12e +COBRA_toolbox commit ef3990e SBML_level 3 SBML_version 1 fbc_version 2 diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index da908964..9e2488d9 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -46209,6 +46209,3514 @@ + + + +

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NOTES: MNXM11

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NOTES: MNXM1018

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id: s_4133 + - name: acetoacetate + - compartment: e + - formula: C4H5O3 + - charge: -1 + - annotation: !!omap + - chebi: CHEBI:13705 + - kegg.compound: C00164 + - !!omap + - id: s_4134 + - name: N(alpha)-acetyl-L-methionine + - compartment: c + - formula: C7H12NO3S + - charge: -1 + - annotation: !!omap + - chebi: CHEBI:132957 + - kegg.compound: C02712 + - !!omap + - id: s_4135 + - name: N(alpha)-acetyl-L-methionine + - compartment: e + - formula: C7H12NO3S + - charge: -1 + - annotation: !!omap + - chebi: CHEBI:132957 + - kegg.compound: C02712 + - !!omap + - id: s_4136 + - name: 3-oxalomalate(3-) + - compartment: c + - formula: C6H3O8 + - charge: -3 + - annotation: !!omap + - chebi: CHEBI:15593 + - kegg.compound: C01990 + - !!omap + - id: s_4137 + - name: 3-oxalomalate(3-) + - compartment: e + - formula: C6H3O8 + - charge: -3 + - annotation: !!omap + - chebi: CHEBI:15593 + - kegg.compound: C01990 + - !!omap + - id: s_4138 + - name: L-cysteate + - compartment: c + - formula: C3H6NO5S + - charge: -1 + - annotation: !!omap + - chebi: CHEBI:58090 + - kegg.compound: C00506 + - !!omap + - id: s_4139 + - name: L-cysteate + - compartment: e + - formula: C3H6NO5S + - charge: -1 + - annotation: !!omap + - chebi: CHEBI:58090 + - kegg.compound: C00506 + - !!omap + - id: s_4140 + - name: alpha-maltotriose + - compartment: e + - formula: C18H32O16 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:61993 + - kegg.compound: C01835 + - !!omap + - id: s_4141 + - name: 2-phospho-D-glyceric acid + - compartment: e + - formula: C3H4O7P + - charge: -3 + - annotation: !!omap + - chebi: CHEBI:58289 + - kegg.compound: C00631 + - !!omap + - id: s_4142 + - name: 3-phosphonato-D-glycerate(3-) + - compartment: e + - formula: C3H4O7P + - charge: -3 + - annotation: !!omap + - chebi: CHEBI:58272 + - kegg.compound: C00197 + - !!omap + - id: s_4143 + - name: Met-Ala + - compartment: e + - formula: C8H16N2O3S + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:73610 + - !!omap + - id: s_4144 + - name: Met-Ala + - compartment: c + - formula: C8H16N2O3S + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:73610 + - !!omap + - id: s_4145 + - name: D-glucose 1-phosphate + - compartment: e + - formula: C6H11O9P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:57629 + - kegg.compound: C00103 + - !!omap + - id: s_4146 + - name: carbamoyl phosphate + - compartment: e + - formula: CH2NO5P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:58228 + - kegg.compound: C00169 + - !!omap + - id: s_4147 + - name: 3-phospho-serine + - compartment: e + - formula: C3H6NO6P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:57524 + - kegg.compound: C01005 + - !!omap + - id: s_4148 + - name: GMP + - compartment: e + - formula: C10H12N5O8P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:58115 + - kegg.compound: C00144 + - !!omap + - id: s_4149 + - name: myo-inositol hexakisphosphate + - compartment: e + - formula: C6H6O24P6 + - charge: -12 + - annotation: !!omap + - chebi: CHEBI:58130 + - kegg.compound: C01204 + - !!omap + - id: s_4150 + - name: D-glucose 6-phosphate + - compartment: e + - formula: C6H11O9P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:61548 + - kegg.compound: C00092 + - !!omap + - id: s_4151 + - name: UMP + - compartment: e + - formula: C9H11N2O9P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:57865 + - kegg.compound: C00105 + - !!omap + - id: s_4152 + - name: phosphoenolpyruvate + - compartment: e + - formula: C3H2O6P + - charge: -3 + - annotation: !!omap + - chebi: CHEBI:58702 + - kegg.compound: C00074 + - !!omap + - id: s_4153 + - name: D-mannose 6-phosphate + - compartment: e + - formula: C6H11O9P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:58735 + - kegg.compound: C00275 + - !!omap + - id: s_4154 + - name: O-phosphoethanolamine + - compartment: e + - formula: C2H7NO4P + - charge: -1 + - annotation: !!omap + - chebi: CHEBI:58190 + - kegg.compound: C00346 + - !!omap + - id: s_4155 + - name: 6-phospho-D-gluconate + - compartment: e + - formula: C6H10O10P + - charge: -3 + - annotation: !!omap + - chebi: CHEBI:58759 + - kegg.compound: C00345 + - !!omap + - id: s_4156 + - name: D-mannose 1-phosphate + - compartment: e + - formula: C6H11O9P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:58409 + - kegg.compound: C00636 + - !!omap + - id: s_4157 + - name: diphosphate + - compartment: e + - formula: HO7P2 + - charge: -3 + - annotation: !!omap + - chebi: CHEBI:33019 + - kegg.compound: C00013 + - !!omap + - id: s_4158 + - name: choline phosphate + - compartment: e + - formula: C5H13NO4P + - charge: -1 + - annotation: !!omap + - chebi: CHEBI:295975 + - kegg.compound: C00588 + - !!omap + - id: s_4159 + - name: thiosulfate + - compartment: e + - formula: HO3S2 + - charge: -1 + - annotation: !!omap + - chebi: CHEBI:33542 + - kegg.compound: C00320 + - !!omap + - id: s_4160 + - name: AMP + - compartment: e + - formula: C10H12N5O7P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:456215 + - kegg.compound: C00020 + - !!omap + - id: s_4161 + - name: 2',3'-cyclic AMP + - compartment: e + - formula: C10H11N5O6P + - charge: -1 + - annotation: !!omap + - chebi: CHEBI:60879 + - kegg.compound: C02353 + - !!omap + - id: s_4162 + - name: adenosine 2'-phosphate + - compartment: e + - formula: C10H12N5O7P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:77740 + - kegg.compound: C00946 + - !!omap + - id: s_4163 + - name: CMP + - compartment: e + - formula: C9H12N3O8P + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:60377 + - kegg.compound: C00055 + - !!omap + - id: s_4164 + - name: D-Glucosamine + - compartment: e + - formula: C6H14NO5 + - charge: 1 + - annotation: !!omap + - chebi: CHEBI:58723 + - kegg.compound: C00329 + - !!omap + - id: s_4165 + - name: 2-deoxy-D-ribose + - compartment: e + - formula: C5H10O4 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:28816 + - kegg.compound: C08347 + - !!omap + - id: s_4166 + - name: L-citrulline + - compartment: e + - formula: C6H13N3O3 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:16349 + - kegg.compound: C00327 + - !!omap + - id: s_4167 + - name: glycerone + - compartment: e + - formula: C3H6O3 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:16016 + - kegg.compound: C00184 + - !!omap + - id: s_4168 + - name: Ala-Leu + - compartment: e + - formula: C9H18N2O3 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:73770 + - !!omap + - id: s_4169 + - name: Ala-Leu + - compartment: c + - formula: C9H18N2O3 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:73770 + - !!omap + - id: s_4170 + - name: Ala-Gly + - compartment: e + - formula: C5H10N2O3 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:73757 + - !!omap + - id: s_4171 + - name: Ala-Gly + - compartment: c + - formula: C5H10N2O3 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:73757 + - !!omap + - id: s_4172 + - name: N-acetyl-L-glutamate + - compartment: e + - formula: C7H9NO5 + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:44337 + - kegg.compound: C00624 + - !!omap + - id: s_4173 + - name: N-acetyl-L-glutamate + - compartment: c + - formula: C7H9NO5 + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:44337 + - kegg.compound: C00624 + - !!omap + - id: s_4174 + - name: lipoamide + - compartment: e + - formula: C8H15NOS2 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:17460 + - kegg.compound: C00248 + - !!omap + - id: s_4175 + - name: lipoamide + - compartment: c + - formula: C8H15NOS2 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:17460 + - kegg.compound: C00248 + - !!omap + - id: s_4176 + - name: L-Methionine S-oxide + - compartment: e + - formula: C5H11NO3S + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:17016 + - kegg.compound: C02989 + - !!omap + - id: s_4177 + - name: homogentisate + - compartment: c + - formula: C8H7O4 + - charge: -1 + - annotation: !!omap + - chebi: CHEBI:16169 + - kegg.compound: C00544 + - !!omap + - id: s_4178 + - name: 4-maleylacetoacetate + - compartment: c + - formula: C8H6O6 + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:17105 + - kegg.compound: C01036 + - !!omap + - id: s_4179 + - name: 4-fumarylacetoacetate + - compartment: c + - formula: C8H6O6 + - charge: -2 + - annotation: !!omap + - chebi: CHEBI:18034 + - kegg.compound: C01061 + - !!omap + - id: s_4180 + - name: L-xylulose + - compartment: c + - formula: C5H10O5 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:17140 + - kegg.compound: C00310 + - !!omap + - id: s_4181 + - name: D-arabinitol + - compartment: c + - formula: C5H12O5 + - charge: 0 + - annotation: !!omap + - chebi: CHEBI:18333 + - kegg.compound: C01904 - reactions: - !!omap - id: r_0001 diff --git a/README.md b/README.md index 7aac4669..8eff6134 100644 --- a/README.md +++ b/README.md @@ -10,13 +10,13 @@ This repository contains the current consensus genome-scale metabolic model of _ **GEM Category:** Species; **Utilisation:** predictive simulation, multi-omics integrative analysis, _in silico_ strain design, model template; **Field:** metabolic-network reconstruction; **Type of Model:** curated, reconstruction; **Model Source:** [Yeast 7.6](https://sourceforge.net/projects/yeast/); **Taxonomy:** _Saccharomyces cerevisiae_; **Metabolic System:** General Metabolism; **Condition:** aerobic, glucose-limited, defined media, maximization of growth. -* Last update: 2018-08-07 +* Last update: 2018-08-26 * Main Model Descriptors: |Taxonomy | Template Model | Reactions | Metabolites| Genes | |:-------:|:--------------:|:---------:|:----------:|:-----:| -|_Saccharomyces cerevisiae_|[Yeast 7.6](https://sourceforge.net/projects/yeast/)|3703|2518|1133| +|_Saccharomyces cerevisiae_|[Yeast 7.6](https://sourceforge.net/projects/yeast/)|3703|2666|1133| This repository is administered by Benjamín J. Sánchez ([@BenjaSanchez](https://github.com/benjasanchez)), Division of Systems and Synthetic Biology, Department of Biology and Biological Engineering, Chalmers University of Technology. From ecadfcc04d7807d199a9755b3a123a12ef93791d Mon Sep 17 00:00:00 2001 From: FEIRANL Date: Sun, 26 Aug 2018 00:20:05 +0200 Subject: [PATCH 05/27] feat-rxn: add new rxns into model add new rxns into model --- ModelFiles/boundaryMets.txt | 2 + ModelFiles/txt/yeastGEM.txt | 155 ++ ModelFiles/xml/yeastGEM.xml | 4286 +++++++++++++++++++++++++++++++++++ ModelFiles/yml/yeastGEM.yml | 1792 +++++++++++++++ README.md | 2 +- 5 files changed, 6236 insertions(+), 1 deletion(-) diff --git a/ModelFiles/boundaryMets.txt b/ModelFiles/boundaryMets.txt index e1ac8e68..09add12b 100644 --- a/ModelFiles/boundaryMets.txt +++ b/ModelFiles/boundaryMets.txt @@ -166,3 +166,5 @@ s_3715[e] raffinose [extracellular] s_3716[e] melibiose [extracellular] s_3746[c] lipid backbone [cytoplasm] s_3747[c] lipid chain [cytoplasm] +s_4074[e] cysteamine [extracellular] +s_4124[e] methanol [extracellular] diff --git a/ModelFiles/txt/yeastGEM.txt b/ModelFiles/txt/yeastGEM.txt index 54463b54..197c329c 100644 --- a/ModelFiles/txt/yeastGEM.txt +++ b/ModelFiles/txt/yeastGEM.txt @@ -3702,3 +3702,158 @@ r_4337 s_0437[m] + s_0807[m] + s_4022[m] <=> s_0397[m] + s_0799[m] + s_1326[m] r_4338 s_0803[c] + s_4024[c] <=> 2 s_3951[c] YOL157C -1000.00 1000.00 0.00 r_4339 s_3764[er] <=> s_4025[g] YEL004W -1000.00 1000.00 0.00 r_4340 s_0373[c] + s_4032[c] <=> s_0529[c] + s_0794[c] + s_4033[c] YEL066W -1000.00 1000.00 0.00 +r_4341 s_4063[e] <=> s_4062[c] -1000.00 1000.00 0.00 +r_4342 s_0803[c] + s_4062[c] -> s_0765[c] + s_1322[c] 0.00 1000.00 0.00 +r_4343 s_0796[e] + s_4065[e] <=> s_0794[c] + s_4064[c] -1000.00 1000.00 0.00 +r_4344 s_0803[c] + s_4064[c] -> s_1045[c] + s_1322[c] 0.00 1000.00 0.00 +r_4345 s_0803[c] + s_4066[c] -> s_0790[c] + s_1322[c] 0.00 1000.00 0.00 +r_4346 s_0796[e] + s_4067[e] <=> s_0794[c] + s_4066[c] -1000.00 1000.00 0.00 +r_4347 s_0803[c] + s_4068[c] -> s_0790[c] + s_1322[c] 0.00 1000.00 0.00 +r_4348 s_0796[e] + s_4069[e] <=> s_0794[c] + s_4068[c] -1000.00 1000.00 0.00 +r_4349 s_0796[e] + s_4070[e] <=> s_0794[c] + s_4071[c] -1000.00 1000.00 0.00 +r_4350 s_0803[c] + s_4071[c] -> s_1322[c] + s_3997[c] 0.00 1000.00 0.00 +r_4351 s_0803[c] + s_4072[c] -> s_1322[c] + s_4073[c] 0.00 1000.00 0.00 +r_4352 s_4075[e] <=> s_4072[c] -1000.00 1000.00 0.00 +r_4353 s_1275[c] + s_4073[c] -> s_0794[c] + s_4076[c] 0.00 1000.00 0.00 +r_4354 s_0803[c] + s_1198[c] + s_4076[c] -> s_0794[c] + s_1203[c] + s_1471[c] 0.00 1000.00 0.00 +r_4355 s_0178[c] + s_0991[c] <=> s_0180[c] + s_4079[c] -1000.00 1000.00 0.00 +r_4356 s_0796[e] + s_4080[e] <=> s_0794[c] + s_4079[c] -1000.00 1000.00 0.00 +r_4357 s_0803[c] + s_4081[c] -> s_1322[c] + s_1556[c] 0.00 1000.00 0.00 +r_4358 s_0796[e] + s_4082[e] <=> s_0794[c] + s_4081[c] -1000.00 1000.00 0.00 +r_4359 s_0803[c] + s_4083[c] -> s_1322[c] + s_1556[c] 0.00 1000.00 0.00 +r_4360 s_0796[e] + s_4084[e] <=> s_0794[c] + s_4083[c] -1000.00 1000.00 0.00 +r_4361 s_0796[e] + s_4085[e] <=> s_0794[c] + s_4086[c] -1000.00 1000.00 0.00 +r_4362 s_0810[v] + s_4087[v] -> s_3758[v] + s_3839[v] 0.00 1000.00 0.00 +r_4363 s_4088[c] -> s_1322[c] + s_4089[c] 0.00 1000.00 0.00 +r_4364 s_0796[e] + s_4090[e] <=> s_0794[c] + s_4088[c] -1000.00 1000.00 0.00 +r_4365 s_0796[e] + s_4091[e] <=> s_0794[c] + s_4089[c] -1000.00 1000.00 0.00 +r_4366 s_0394[c] + s_0794[c] + s_4092[c] <=> s_0434[c] + s_0965[c] -1000.00 1000.00 0.00 +r_4367 s_0796[e] + s_4093[e] <=> s_0794[c] + s_4092[c] -1000.00 1000.00 0.00 +r_4368 s_0803[c] + s_4096[c] -> s_1051[c] + s_1322[c] 0.00 1000.00 0.00 +r_4369 s_0796[e] + s_4099[e] <=> s_0794[c] + s_4098[c] -1000.00 1000.00 0.00 +r_4370 s_0803[c] + s_4100[c] -> s_0543[c] + s_1322[c] 0.00 1000.00 0.00 +r_4371 s_0796[e] + s_4101[e] <=> s_0794[c] + s_4100[c] -1000.00 1000.00 0.00 +r_4372 s_0803[c] + s_4102[c] -> s_0794[c] + s_4081[c] 0.00 1000.00 0.00 +r_4373 s_0796[e] + s_4103[e] <=> s_0794[c] + s_4102[c] -1000.00 1000.00 0.00 +r_4374 s_0803[c] + s_4104[c] -> s_0955[c] + s_1469[c] 0.00 1000.00 0.00 +r_4375 s_0796[e] + s_4105[e] <=> s_0794[c] + s_4104[c] -1000.00 1000.00 0.00 +r_4376 s_0803[c] + s_4106[c] -> s_0386[c] + s_1322[c] 0.00 1000.00 0.00 +r_4377 s_4107[e] <=> s_4106[c] -1000.00 1000.00 0.00 +r_4378 s_0803[c] + s_4108[c] -> s_0553[c] + s_0563[c] 0.00 1000.00 0.00 +r_4379 s_0796[e] + s_4109[e] <=> s_0794[c] + s_4108[c] -1000.00 1000.00 0.00 +r_4380 s_0529[c] + s_0794[c] + s_4110[c] <=> s_0373[c] + s_0981[c] -1000.00 1000.00 0.00 +r_4381 s_0796[e] + s_4111[e] <=> s_0794[c] + s_4110[c] -1000.00 1000.00 0.00 +r_4382 2 s_0709[m] + s_4112[c] <=> 2 s_0710[m] + 2 s_4113[c] -1000.00 1000.00 0.00 +r_4383 s_4114[e] <=> s_4112[c] -1000.00 1000.00 0.00 +r_4384 s_0794[c] + s_1212[c] + s_4117[c] -> s_1207[c] + s_3875[c] 0.00 1000.00 0.00 +r_4385 s_0796[e] + s_4118[e] <=> s_0794[c] + s_4117[c] -1000.00 1000.00 0.00 +r_4386 s_0810[v] + s_4121[v] -> s_0977[v] + s_3759[v] 0.00 1000.00 0.00 +r_4387 s_0796[e] + s_4119[e] <=> s_0794[c] + s_4120[c] -1000.00 1000.00 0.00 +r_4388 s_0803[c] + s_4126[c] -> s_0794[c] + s_4100[c] 0.00 1000.00 0.00 +r_4389 s_0796[e] + s_4127[e] <=> s_0794[c] + s_4126[c] -1000.00 1000.00 0.00 +r_4390 s_0803[c] + s_4122[c] <=> s_0563[c] + s_4123[c] -1000.00 1000.00 0.00 +r_4391 s_4123[c] -> s_4124[e] 0.00 1000.00 0.00 +r_4392 s_0796[e] + s_4125[e] <=> s_0794[c] + s_4122[c] -1000.00 1000.00 0.00 +r_4393 s_0434[c] + s_4128[c] -> s_0394[c] + s_0794[c] + s_4129[c] 0.00 1000.00 0.00 +r_4394 s_4129[c] <=> s_0557[c] -1000.00 1000.00 0.00 +r_4395 s_4130[e] <=> s_4128[c] -1000.00 1000.00 0.00 +r_4396 s_0434[c] + s_0529[c] + s_4132[c] -> s_0367[c] + s_0423[c] + s_0633[c] 0.00 1000.00 0.00 +r_4397 s_0803[c] + s_4134[c] <=> s_0362[c] + s_1029[c] -1000.00 1000.00 0.00 +r_4398 s_0796[e] + s_4034[e] <=> s_0794[c] + s_4035[c] -1000.00 1000.00 0.00 +r_4399 s_0794[c] + s_4038[c] <=> s_0802[v] + s_4039[v] -1000.00 1000.00 0.00 +r_4400 s_0805[e] + s_4140[e] -> s_0565[e] + s_1106[e] 0.00 1000.00 0.00 +r_4401 s_0794[c] + s_4041[c] <=> s_0802[v] + s_4042[v] -1000.00 1000.00 0.00 +r_4402 s_0796[e] + s_4040[e] <=> s_0794[c] + s_4041[c] -1000.00 1000.00 0.00 +r_4403 s_0803[c] + s_4098[c] -> s_0633[c] + s_1322[c] ( YHR201C or YDR452W ) 0.00 1000.00 0.00 +r_4404 s_0796[e] + s_4053[e] <=> s_0794[c] + s_4054[c] -1000.00 1000.00 0.00 +r_4405 s_4049[e] <=> s_4048[c] -1000.00 1000.00 0.00 +r_4406 s_0796[e] + s_4078[e] <=> s_0794[c] + s_4077[c] -1000.00 1000.00 0.00 +r_4407 s_0803[c] + s_4077[c] <=> s_1322[c] + s_3904[c] -1000.00 1000.00 0.00 +r_4408 s_0796[e] + s_4037[e] <=> s_0794[c] + s_4038[c] -1000.00 1000.00 0.00 +r_4409 s_0810[v] + s_4039[v] -> s_0996[v] + s_3759[v] 0.00 1000.00 0.00 +r_4410 s_4136[c] <=> s_0779[c] + s_1271[c] -1000.00 1000.00 0.00 +r_4411 s_0803[c] + s_4138[c] -> s_0419[c] + s_1399[c] + s_1469[c] 0.00 1000.00 0.00 +r_4412 s_0803[c] + s_4094[c] -> s_0794[c] + s_4066[c] 0.00 1000.00 0.00 +r_4413 s_0803[c] + s_4044[c] -> s_1322[c] + s_1493[c] 0.00 1000.00 0.00 +r_4414 s_0810[v] + s_4036[v] -> s_1002[v] + s_3759[v] 0.00 1000.00 0.00 +r_4415 s_0810[v] + s_4052[v] -> s_1009[v] + s_3759[v] 0.00 1000.00 0.00 +r_4416 s_0810[v] + s_4042[v] -> s_3759[v] + s_4043[v] 0.00 1000.00 0.00 +r_4417 s_0810[v] + s_4055[v] -> s_0972[v] + s_3839[v] 0.00 1000.00 0.00 +r_4418 s_0810[v] + s_4058[v] -> s_1002[v] + s_3839[v] 0.00 1000.00 0.00 +r_4419 s_0796[e] + s_4139[e] <=> s_0794[c] + s_4138[c] -1000.00 1000.00 0.00 +r_4420 s_0805[e] + s_4131[e] <=> s_0554[e] + s_0565[e] -1000.00 1000.00 0.00 +r_4421 s_0796[e] + s_4116[e] <=> s_0794[c] + s_4115[c] -1000.00 1000.00 0.00 +r_4422 s_0796[e] + s_4137[e] <=> s_0794[c] + s_4136[c] -1000.00 1000.00 0.00 +r_4423 s_0794[c] + s_4086[c] <=> s_0802[v] + s_4087[v] -1000.00 1000.00 0.00 +r_4424 s_0796[e] + s_4056[e] <=> s_0794[c] + s_4057[c] -1000.00 1000.00 0.00 +r_4425 s_0794[c] + s_4057[c] <=> s_0802[v] + s_4058[v] -1000.00 1000.00 0.00 +r_4426 s_0794[c] + s_4035[c] <=> s_0802[v] + s_4036[v] -1000.00 1000.00 0.00 +r_4427 s_0796[e] + s_4135[e] <=> s_0794[c] + s_4134[c] -1000.00 1000.00 0.00 +r_4428 s_0796[e] + s_4097[e] <=> s_0794[c] + s_4096[c] -1000.00 1000.00 0.00 +r_4429 s_0796[e] + s_4050[e] <=> s_0794[c] + s_4051[c] -1000.00 1000.00 0.00 +r_4430 s_0794[c] + s_4051[c] <=> s_0802[v] + s_4052[v] -1000.00 1000.00 0.00 +r_4431 s_0794[c] + s_4120[c] <=> s_0802[v] + s_4121[v] -1000.00 1000.00 0.00 +r_4432 s_0717[c] + s_1275[c] + s_4115[c] -> s_0714[c] + s_0775[c] + s_0794[c] + s_0803[c] + s_1469[c] 0.00 1000.00 0.00 +r_4433 s_4045[e] <=> s_4044[c] -1000.00 1000.00 0.00 +r_4434 s_4047[e] <=> s_4046[c] -1000.00 1000.00 0.00 +r_4435 s_0803[c] + s_4048[c] -> s_0765[c] + s_1322[c] ( YIL053W or YER062C ) 0.00 1000.00 0.00 +r_4436 s_0803[c] + s_4046[c] -> s_1322[c] + s_1493[c] 0.00 1000.00 0.00 +r_4437 s_0796[e] + s_4059[e] <=> s_0794[c] + s_4060[c] -1000.00 1000.00 0.00 +r_4438 s_0794[c] + s_4060[c] <=> s_0802[v] + s_4061[v] -1000.00 1000.00 0.00 +r_4439 s_0810[v] + s_4061[v] -> s_0996[v] + s_3839[v] 0.00 1000.00 0.00 +r_4440 s_1029[c] <=> s_3758[v] -1000.00 1000.00 0.00 +r_4441 s_1045[c] <=> s_4043[v] -1000.00 1000.00 0.00 +r_4442 s_4074[e] <=> -1000.00 1000.00 0.00 +r_4443 s_4095[e] <=> s_4094[c] -1000.00 1000.00 0.00 +r_4444 s_0796[e] + s_4141[e] <=> s_0188[c] + s_0794[c] -1000.00 1000.00 0.00 +r_4445 s_0796[e] + s_4142[e] <=> s_0260[c] + s_0794[c] -1000.00 1000.00 0.00 +r_4446 s_4145[e] <=> s_0567[c] -1000.00 1000.00 0.00 +r_4447 s_4146[e] <=> s_0455[c] -1000.00 1000.00 0.00 +r_4448 s_0796[e] + s_4143[e] <=> s_0794[c] + s_4144[c] -1000.00 1000.00 0.00 +r_4449 s_0794[c] + s_4144[c] <=> s_0802[v] + s_3757[v] -1000.00 1000.00 0.00 +r_4450 s_0796[e] + s_4147[e] <=> s_0259[c] + s_0794[c] -1000.00 1000.00 0.00 +r_4451 s_0796[e] + s_4148[e] <=> s_0782[c] + s_0794[c] -1000.00 1000.00 0.00 +r_4452 s_4149[e] <=> s_1158[c] -1000.00 1000.00 0.00 +r_4453 s_4150[e] <=> s_0568[c] -1000.00 1000.00 0.00 +r_4454 s_4151[e] <=> s_1545[c] -1000.00 1000.00 0.00 +r_4455 s_0796[e] + s_4152[e] <=> s_0794[c] + s_1360[c] -1000.00 1000.00 0.00 +r_4456 s_4153[e] <=> s_0574[c] -1000.00 1000.00 0.00 +r_4457 s_0796[e] + s_4154[e] <=> s_0794[c] + s_1239[c] -1000.00 1000.00 0.00 +r_4458 s_0796[e] + s_4155[e] <=> s_0340[c] + s_0794[c] -1000.00 1000.00 0.00 +r_4459 s_0796[e] + s_4156[e] <=> s_0573[c] + s_0794[c] -1000.00 1000.00 0.00 +r_4460 2 s_0796[e] + s_4157[e] <=> s_0633[c] + 2 s_0794[c] -1000.00 1000.00 0.00 +r_4461 s_4158[e] <=> s_0514[c] -1000.00 1000.00 0.00 +r_4462 s_4159[e] <=> s_4113[c] -1000.00 1000.00 0.00 +r_4463 s_0796[e] + s_4160[e] <=> s_0423[c] + s_0794[c] -1000.00 1000.00 0.00 +r_4464 s_4161[e] <=> s_0131[c] -1000.00 1000.00 0.00 +r_4465 s_0796[e] + s_4162[e] <=> s_0389[c] + s_0794[c] -1000.00 1000.00 0.00 +r_4466 s_0796[e] + s_4163[e] <=> s_0526[c] + s_0794[c] -1000.00 1000.00 0.00 +r_4467 s_4164[e] <=> s_3953[c] -1000.00 1000.00 0.00 +r_4468 s_4165[e] <=> s_0152[c] -1000.00 1000.00 0.00 +r_4469 s_0796[e] + s_4166[e] <=> s_0794[c] + s_0979[c] -1000.00 1000.00 0.00 +r_4470 s_4167[e] <=> s_0771[c] -1000.00 1000.00 0.00 +r_4471 s_0796[e] + s_4168[e] <=> s_0794[c] + s_4169[c] -1000.00 1000.00 0.00 +r_4472 s_0794[c] + s_4169[c] <=> s_0802[v] + s_3840[v] -1000.00 1000.00 0.00 +r_4473 s_0796[e] + s_4170[e] <=> s_0794[c] + s_4171[c] -1000.00 1000.00 0.00 +r_4474 s_0794[c] + s_4171[c] <=> s_0802[v] + s_3838[v] -1000.00 1000.00 0.00 +r_4475 s_4172[e] <=> s_4173[c] -1000.00 1000.00 0.00 +r_4476 s_4173[c] <=> s_1192[m] -1000.00 1000.00 0.00 +r_4477 s_0796[e] + s_4174[e] <=> s_0794[c] + s_4175[c] -1000.00 1000.00 0.00 +r_4478 s_4176[e] <=> s_3837[c] -1000.00 1000.00 0.00 +r_4479 s_0794[c] + s_4054[c] <=> s_0802[v] + s_4055[v] -1000.00 1000.00 0.00 +r_4480 s_0796[e] + s_4074[e] <=> s_0794[c] + s_4073[c] -1000.00 1000.00 0.00 +r_4481 s_0841[c] + 2 s_1275[c] -> s_0794[c] + s_1467[c] 0.00 1000.00 0.00 +r_4482 s_0794[c] + s_0955[c] <=> s_0802[v] + s_3759[v] -1000.00 1000.00 0.00 +r_4483 s_0794[c] + s_1003[c] <=> s_0802[v] + s_3839[v] -1000.00 1000.00 0.00 +r_4484 s_0841[c] + s_1241[c] <=> s_1012[c] + s_1458[c] ( YJR130C or YLL058W or YML082W ) -1000.00 1000.00 0.00 +r_4485 s_0204[c] + s_1275[c] -> s_0456[c] + s_4177[c] 0.00 1000.00 0.00 +r_4486 s_1275[c] + s_4177[c] -> s_0794[c] + s_4178[c] 0.00 1000.00 0.00 +r_4487 s_4178[c] -> s_4179[c] 0.00 1000.00 0.00 +r_4488 s_0803[c] + s_4179[c] -> s_0725[c] + s_0794[c] + s_4132[c] 0.00 1000.00 0.00 +r_4489 s_0961[c] + s_1198[c] -> s_0794[c] + s_1203[c] + s_4180[c] 0.00 1000.00 0.00 +r_4490 s_0794[c] + s_1212[c] + s_4180[c] <=> s_1207[c] + s_1566[c] -1000.00 1000.00 0.00 +r_4491 s_0548[c] + s_0794[c] + s_1212[c] -> s_1207[c] + s_4181[c] 0.00 1000.00 0.00 +r_4492 s_1198[c] + s_4181[c] -> s_0580[c] + s_0794[c] + s_1203[c] 0.00 1000.00 0.00 +r_4493 s_4133[e] <=> s_4132[c] -1000.00 1000.00 0.00 +r_4494 s_4124[e] <=> -1000.00 1000.00 0.00 +r_4495 s_0389[c] + s_0803[c] -> s_0386[c] + s_1322[c] 0.00 1000.00 0.00 diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index 9e2488d9..22ad2841 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -178354,6 +178354,4292 @@ + + + +

Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

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s_4166: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4470 + - name: Dihydroxyacetone transport via facilitated diffusion + - metabolites: !!omap + - s_0771: 1 + - s_4167: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4471 + - name: Ala-Leu transport via proton symport (excelluar to cytosol) + - metabolites: !!omap + - s_0794: 1 + - s_0796: -1 + - s_4168: -1 + - s_4169: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4472 + - name: Ala-Leu transport via proton symport (cytosol to vacuole) + - metabolites: !!omap + - s_0794: -1 + - s_0802: 1 + - s_3840: 1 + - s_4169: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4473 + - name: L-alanylglycine transport via proton antiport + - metabolites: !!omap + - s_0794: 1 + - s_0796: -1 + - s_4170: -1 + - s_4171: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4474 + - name: L-alanylglycine transport via proton antiport + - metabolites: !!omap + - s_0794: -1 + - s_0802: 1 + - s_3838: 1 + - s_4171: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4475 + - name: N-acetyl-L-glutamate transport + - metabolites: !!omap + - s_4172: -1 + - s_4173: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4476 + - name: N-acetyl-L-glutamate transport + - metabolites: !!omap + - s_1192: 1 + - s_4173: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4477 + - name: Lipoamide transport via proton symport + - metabolites: !!omap + - s_0794: 1 + - s_0796: -1 + - s_4174: -1 + - s_4175: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4478 + - name: L-methionine S-oxide diffusion (extracellular) + - metabolites: !!omap + - s_3837: 1 + - s_4176: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4479 + - name: Gly-Asn transport via proton symport + - metabolites: !!omap + - s_0794: -1 + - s_0802: 1 + - s_4054: -1 + - s_4055: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4480 + - name: Cysteamine transport via proton antiport + - metabolites: !!omap + - s_0794: 1 + - s_0796: -1 + - s_4073: 1 + - s_4074: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4481 + - name: Hydrogen sulfide oxidation + - metabolites: !!omap + - s_0794: 1 + - s_0841: -1 + - s_1275: -2 + - s_1467: 1 + - lower_bound: 0 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4482 + - name: L-alanine transport in via proton symport + - metabolites: !!omap + - s_0794: -1 + - s_0802: 1 + - s_0955: -1 + - s_3759: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4483 + - name: Glycine mitochondrial transport + - metabolites: !!omap + - s_0794: -1 + - s_0802: 1 + - s_1003: -1 + - s_3839: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4484 + - name: O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) + - metabolites: !!omap + - s_0841: -1 + - s_1012: 1 + - s_1241: -1 + - s_1458: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: YJR130C or YLL058W or YML082W + - annotation: !!omap + - ec-code: + - 2.5.1.- + - 2.5.1.48 + - kegg.reaction: R01288 + - confidence_score: 0 + - !!omap + - id: r_4485 + - name: 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) + - metabolites: !!omap + - s_0204: -1 + - s_0456: 1 + - s_1275: -1 + - s_4177: 1 + - lower_bound: 0 + - upper_bound: 1000 + - annotation: !!omap + - ec-code: 1.13.11.27 + - kegg.reaction: R02521 + - confidence_score: 0 + - !!omap + - id: r_4486 + - name: Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) + - metabolites: !!omap + - s_0794: 1 + - s_1275: -1 + - s_4177: -1 + - s_4178: 1 + - lower_bound: 0 + - upper_bound: 1000 + - annotation: !!omap + - ec-code: 1.13.11.5 + - kegg.reaction: R02519 + - confidence_score: 0 + - !!omap + - id: r_4487 + - name: 4-Maleylacetoacetate cis-trans-isomerase + - metabolites: !!omap + - s_4178: -1 + - s_4179: 1 + - lower_bound: 0 + - upper_bound: 1000 + - annotation: !!omap + - ec-code: 5.2.1.2 + - kegg.reaction: R03181 + - confidence_score: 0 + - !!omap + - id: r_4488 + - name: 4-fumarylacetoacetate fumarylhydrolase + - metabolites: !!omap + - s_0725: 1 + - s_0794: 1 + - s_0803: -1 + - s_4132: 1 + - s_4179: -1 + - lower_bound: 0 + - upper_bound: 1000 + - annotation: !!omap + - ec-code: 3.7.1.2 + - kegg.reaction: R01364 + - confidence_score: 0 + - !!omap + - id: r_4489 + - name: L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming) + - metabolites: !!omap + - s_0794: 1 + - s_0961: -1 + - s_1198: -1 + - s_1203: 1 + - s_4180: 1 + - lower_bound: 0 + - upper_bound: 1000 + - annotation: !!omap + - ec-code: 1.1.1.12 + - kegg.reaction: R01903 + - confidence_score: 0 + - !!omap + - id: r_4490 + - name: Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) + - metabolites: !!omap + - s_0794: -1 + - s_1207: 1 + - s_1212: -1 + - s_1566: 1 + - s_4180: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - annotation: !!omap + - ec-code: 1.1.1.10 + - kegg.reaction: R01904 + - confidence_score: 0 + - !!omap + - id: r_4491 + - name: arabinose reductase (D-arabinose) + - metabolites: !!omap + - s_0548: -1 + - s_0794: -1 + - s_1207: 1 + - s_1212: -1 + - s_4181: 1 + - lower_bound: 0 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4492 + - name: D-arabinitol:NAT 4-oxidoreductase + - metabolites: !!omap + - s_0580: 1 + - s_0794: 1 + - s_1198: -1 + - s_1203: 1 + - s_4181: -1 + - lower_bound: 0 + - upper_bound: 1000 + - annotation: !!omap + - ec-code: 1.1.1.11 + - kegg.reaction: R05604 + - confidence_score: 0 + - !!omap + - id: r_4493 + - name: Acetoacetate transport via diffusion + - metabolites: !!omap + - s_4132: 1 + - s_4133: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4494 + - name: Exchange rxns for meoh + - metabolites: !!omap + - s_4124: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - confidence_score: 0 + - !!omap + - id: r_4495 + - name: alkaline phosphatase + - metabolites: !!omap + - s_0386: 1 + - s_0389: -1 + - s_0803: -1 + - s_1322: 1 + - lower_bound: 0 + - upper_bound: 1000 + - annotation: !!omap + - ec-code: 3.1.3.- + - confidence_score: 0 - genes: - !!omap - id: Q0045 diff --git a/README.md b/README.md index 8eff6134..b7c7951d 100644 --- a/README.md +++ b/README.md @@ -16,7 +16,7 @@ This repository contains the current consensus genome-scale metabolic model of _ |Taxonomy | Template Model | Reactions | Metabolites| Genes | |:-------:|:--------------:|:---------:|:----------:|:-----:| -|_Saccharomyces cerevisiae_|[Yeast 7.6](https://sourceforge.net/projects/yeast/)|3703|2666|1133| +|_Saccharomyces cerevisiae_|[Yeast 7.6](https://sourceforge.net/projects/yeast/)|3858|2666|1133| This repository is administered by Benjamín J. Sánchez ([@BenjaSanchez](https://github.com/benjasanchez)), Division of Systems and Synthetic Biology, Department of Biology and Biological Engineering, Chalmers University of Technology. From 155f354e38b4004bac9eda45a2266eb31830a6c9 Mon Sep 17 00:00:00 2001 From: FEIRANL Date: Sun, 26 Aug 2018 00:26:06 +0200 Subject: [PATCH 06/27] feat-data:update model prediction Update model prediction by running SubstrateUsage again. Exchange rxns for those substrates are also added into the model --- .../modelCuration/Biolog_Substrate.tsv | 148 +- ModelFiles/boundaryMets.txt | 59 + ModelFiles/txt/yeastGEM.txt | 59 + ModelFiles/xml/yeastGEM.xml | 1482 ++++++++++++++++- ModelFiles/yml/yeastGEM.yml | 531 ++++++ README.md | 2 +- 6 files changed, 2116 insertions(+), 165 deletions(-) diff --git a/ComplementaryData/modelCuration/Biolog_Substrate.tsv b/ComplementaryData/modelCuration/Biolog_Substrate.tsv index 749af062..09b4bcfc 100644 --- a/ComplementaryData/modelCuration/Biolog_Substrate.tsv +++ b/ComplementaryData/modelCuration/Biolog_Substrate.tsv @@ -10,7 +10,7 @@ Butyric Acid butyrate C NG NG Methyl Pyruvate C NG NG α-Keto-Glutaric Acid 2-oxoglutarate C NG G D,L-Malic Acid C NG NG -L-Alanyl-Glycine Ala-Gly C NG NG +L-Alanyl-Glycine Ala-Gly C NG G Acetic Acid acetate C NG G Succinic Acid succinate C NG G L-Tartaric Acid C NG NG @@ -21,7 +21,7 @@ L-Alaninamide C NG NG L-Serine L-serine C NG G Formic Acid formate C NG G γ-Amino Butyric Acid gamma-aminobutyrate C NG G -Oxalo malicAcid 3-oxalomalate(3-) C G NG +Oxalo malicAcid 3-oxalomalate(3-) C G G Glycyl-L-Glutamic Acid C NG NG β-Hydroxy Butyric Acid C NG NG D-Mannitol Mannitol C NG NG @@ -60,10 +60,10 @@ L-Isoleucine L-isoleucine C NG NG Acetoacetic Acid acetoacetate C G NG Glyoxylic Acid glyoxylate C NG G Tween 20 C NG NG -Palatinose 6-O-alpha-D-glucopyranosyl-D-fructofuranose C G NG +Palatinose 6-O-alpha-D-glucopyranosyl-D-fructofuranose C G G Dextrin Dextrin C NG NG 3-Hydroxy 2-Butanone C NG NG -5-Keto-D-Gluconic Acid 5-dehydro-D-gluconate C G NG +5-Keto-D-Gluconic Acid 5-dehydro-D-gluconate C G G Tyramine C NG NG p-Hydroxy Phenyl Acetic Acid (4-Hydroxyphenylacetate) C NG NG Glucuronamide C G NG @@ -77,16 +77,16 @@ Glycerol glycerol C NG G Mucic Acid C NG NG 3-Methyl Glucose C NG NG D-Fructose-6-Phosphate D-fructose 6-phosphate C NG NG -D-Tagatose D-tagatose C G NG +D-Tagatose D-tagatose C G G N-Acetyl-L-Glutamic Acid N-acetyl-L-glutamate C NG NG -Turanose turanose C G NG -D-Glucose-6-Phosphate D-glucose 6-phosphate C NG NG +Turanose turanose C G G +D-Glucose-6-Phosphate D-glucose 6-phosphate C NG G L-Sorbose L-sorbose C NG NG γ-Hydroxy Butyric Acid C NG NG N-Acetyl-D-Glucosamine N-Acetyl-D-glucosamine C NG NG β-Methyl-D-Glucuronic Acid C NG NG Dulcitol (Galactitol) C NG NG -D-Arabinose D-arabinose C G NG +D-Arabinose D-arabinose C G G N-Acetyl-β-D-Mannosamine C NG NG D-Glucosaminic Acid C NG NG D-Melezitose C NG NG @@ -98,7 +98,7 @@ Tricarballylic Acid C NG NG β-D-Allose C NG NG Chondroitin Sulfate C C NG NG α-Methyl-D Galactoside C NG NG -Maltotriose alpha-maltotriose C G NG +Maltotriose alpha-maltotriose C G G β-Methyl-D-Glucoside C NG NG Tween 40 C NG NG Glycogen glycogen C NG NG @@ -106,7 +106,7 @@ M-Inositol myo-inositol C NG NG Sucrose sucrose C G G D-Saccharic Acid D-Glucarate C NG NG Pectin pectin C NG NG -D-Glucose-1-Phosphate D-glucose 1-phosphate C NG NG +D-Glucose-1-Phosphate D-glucose 1-phosphate C NG G Hydroxy-L Proline C NG NG D-Ribono-1,4-Lactone C NG NG L-Pyroglutamic Acid 5-oxo-L-proline C NG NG @@ -129,7 +129,7 @@ Gelatin C NG NG L-Aspartic Acid L-aspartate C NG G L-Ornithine C NG NG Salicin C NG NG -L-Arabinose L-arabinose C G NG +L-Arabinose L-arabinose C G G L-Histidine L-histidine C NG NG D-Glucuronic Acid C NG NG L-Glucose C NG NG @@ -141,7 +141,7 @@ Acetamide C NG NG I-Erythritol C NG NG Lactitol C NG NG N-Acetyl-D-Glucosaminitol C NG NG -α-Methyl-D-Glucoside methyl alpha-D-glucopyranoside C G NG +α-Methyl-D-Glucoside methyl alpha-D-glucopyranoside C G G D,L-Carnitine C NG NG D,L-α-Glycerol-Phosphate glycerol 3-phosphate C NG NG Sedoheptulosan C NG NG @@ -156,7 +156,7 @@ L-Phenylalanine L-phenylalanine C NG NG Citric Acid citrate C NG G α-Cyclodextrin C NG NG Citraconic Acid C NG NG -L-Arabitol L-arabinitol C NG NG +L-Arabitol L-arabinitol C NG G D-Trehalose trehalose C NG G γ-Cyclodextrin C NG NG L-Methionine L-methionine C NG NG @@ -172,10 +172,10 @@ Phenylethyl-amine C NG NG Xylitol xylitol C NG G m-Hydroxy Phenyl Acetic Acid C NG NG Sec-Butylamine C NG NG -D-Glucosamine D-Glucosamine C G NG +D-Glucosamine D-Glucosamine C G G Sebacic Acid C NG NG Mannan mannan C NG NG -Dihydroxy Acetone glycerone C G NG +Dihydroxy Acetone glycerone C G G 2-Deoxy Adenosine 2'-deoxyadenosine C NG NG Adenosine adenosine C NG G D-Alanine C NG NG @@ -190,16 +190,16 @@ Sorbic Acid C G NG 2-Hydroxy Benzoic Acid C NG NG Glycine L-glycine C NG G Uric Acid N NG NG -Ala-Gln Ala-Gln N G NG -Ala-Leu Ala-Leu N G NG -Ala-Gly Ala-Gly N G NG +Ala-Gln Ala-Gln N G G +Ala-Leu Ala-Leu N G G +Ala-Gly Ala-Gly N G G Xanthine 9H-xanthine N NG NG D,L-Lactamide N NG NG Cytosine cytosine N G G -Gly-Gln Gly-Gln N G NG +Gly-Gln Gly-Gln N G G Guanine guanine N NG G Ethylenediamine N NG NG -Ala-His Ala-His N G NG +Ala-His Ala-His N G G Allantoin allantoin N G G Parabanic Acid N G NG L-Alanine L-alanine N G G @@ -207,24 +207,24 @@ Guanosine guanosine N NG G L-Glutamine L-glutamine N G G L-Leucine L-leucine N G G Thymidine thymidine N NG NG -Gly-Asn Gly-Asn N G NG -Ala-Glu Ala-Glu N G NG +Gly-Asn Gly-Asn N G G +Ala-Glu Ala-Glu N G G Thymine N NG NG Cytidine cytidine N NG G Uracil uracil N NG NG L-Asparagine L-asparagine N G G -Gly-Met Gly-Met N G NG -Ala-Asp Ala-Asp N G NG +Gly-Met Gly-Met N G G +Ala-Asp Ala-Asp N G G γ-Amino-N-Butyric Acid gamma-aminobutyrate N G G D-Alanine N NG NG L-Serine L-serine N G G Urea urea N G G -Gly-Glu Gly-Glu N G NG -Ala-Thr Ala-Thr N G NG +Gly-Glu Gly-Glu N G G +Ala-Thr Ala-Thr N G G δ-Amino-N-Valeric Acid 5-Aminopentanoate N G NG Putrescine putrescine N NG NG Uridine uridine N NG NG -Met-Ala Met-Ala N G NG +Met-Ala Met-Ala N G G Glucuronamide N NG NG D-Serine D-Serine N NG NG L-Lysine L-lysine N NG NG @@ -241,20 +241,20 @@ L-Aspartic Acid L-aspartate N G G Alloxan N NG NG N-Acetyl-D-Glucosamine N-Acetyl-D-glucosamine N NG NG D-Aspartate N G NG -L-Cysteine L-cysteine N G NG +L-Cysteine L-cysteine N G G L-Proline L-proline N G G L-Isoleucine L-isoleucine N G G ε-Amino-N-Caproic Acid N NG NG L-Tryptophan L-tryptophan N G G α-Amino-NValeric Acid N G NG D-Asparagine N NG NG -L-Tyrosine L-tyrosine N G NG +L-Tyrosine L-tyrosine N G G Histamine N NG NG D-Mannosamine N NG NG D-Galactosamine N NG NG L-Arginine L-arginine N G G L-Pyroglutamic Acid 5-oxo-L-proline N NG NG -L-Citrulline L-citrulline N G NG +L-Citrulline L-citrulline N G G Inosine inosine N NG NG Formamide N NG NG Ethylamine N NG NG @@ -277,94 +277,94 @@ L-Ornithine ornithine N G G L-Threonine L-threonine N G G β-Phenylethyl-amine N NG NG Nitrite Nitrite N NG NG -L-Methionine L-methionine N G NG +L-Methionine L-methionine N G G D,L-α-Amino-Caprylic Acid N G NG D-Valine N NG NG -D-Glucosamine D-Glucosamine N NG NG -D,L-α-Amino-N-Butyric Acid 2-aminobutanoate N G NG +D-Glucosamine D-Glucosamine N NG G +D,L-α-Amino-N-Butyric Acid 2-aminobutanoate N G G Adenosine adenosine N NG G Hydroxylamine N NG NG -Phosphoryl Choline choline phosphate P G NG -D,L-α-Glycerol Phosphate glycerol 1-phosphate P G NG +Phosphoryl Choline choline phosphate P G G +D,L-α-Glycerol Phosphate glycerol 1-phosphate P G G O-Phospho-D-Tyrosine P G NG -D-2-Phospho-Glyceric Acid 2-phospho-D-glyceric acid P G NG -Guanosine-5’-monophosphate GMP P G NG -O-Phospho-L-Serine 3-phospho-serine P G NG -O-Phospho-D-Serine O-phosphonatooxy-D-serine(2-) P G NG +D-2-Phospho-Glyceric Acid 2-phospho-D-glyceric acid P G G +Guanosine-5’-monophosphate GMP P G G +O-Phospho-L-Serine 3-phospho-serine P G G +O-Phospho-D-Serine O-phosphonatooxy-D-serine(2-) P G G Phosphate phosphate P G G -Pyrophosphate diphosphate P G NG +Pyrophosphate diphosphate P G G Thiophosphate P G NG -Tripolyphosphate triphosphate P G NG +Tripolyphosphate triphosphate P G G Uridine-5’-monophosphate UMP P G NG Cytidine-5’-monophosphate CMP P G NG -Phosphoenol Pyruvate phosphoenolpyruvate P G NG +Phosphoenol Pyruvate phosphoenolpyruvate P G G Trimetaphosphate P G NG -Phospho-L-Arginine N(omega)-phospho-L-arginine P G NG -Carbamyl Phosphate carbamoyl phosphate P G NG -O-Phosphoryl-Ethanolamine O-phosphoethanolamine P G NG +Phospho-L-Arginine N(omega)-phospho-L-arginine P G G +Carbamyl Phosphate carbamoyl phosphate P G G +O-Phosphoryl-Ethanolamine O-phosphoethanolamine P G G D-Glucosamine-6-Phosphate alpha-D-glucosamine 6-phosphate P G G Phosphocreatine N-phosphocreatine P G NG Dithiophosphate P G NG Thymidine-5’-monophosphate thymidine 5'-monophosphate P G NG Thymidine-3 ’-monophosphate thymidine 3'-monophosphate P G NG -Cysteamine-S-Phosphate cysteamine S-phosphate P G NG +Cysteamine-S-Phosphate cysteamine S-phosphate P G G 2-Deoxy-D-Glucose 6-Phosphate 2-deoxy-D-glucose 6-phosphate P NG NG -Guanosine-2’-monophosphate guanosine 2'-monophosphate P G NG -D-Glucose-6-Phosphate D-glucose 6-phosphate P G NG -β-Glycerol Phosphate glycerol 2-phosphate(2-) P G NG -Guanosine-3’-monophosphate 3'-GMP P G NG -Phospho-Glycolic Acid 2-phosphoglycolate P G NG -6-Phospho-Gluconic Acid 6-phospho-D-gluconate P G NG -D-Mannose-6-Phosphate D-mannose 6-phosphate P G NG +Guanosine-2’-monophosphate guanosine 2'-monophosphate P G G +D-Glucose-6-Phosphate D-glucose 6-phosphate P G G +β-Glycerol Phosphate glycerol 2-phosphate(2-) P G G +Guanosine-3’-monophosphate 3'-GMP P G G +Phospho-Glycolic Acid 2-phosphoglycolate P G G +6-Phospho-Gluconic Acid 6-phospho-D-gluconate P G G +D-Mannose-6-Phosphate D-mannose 6-phosphate P G G Cytidine-3’,5’-cyclic monophosphate 3',5'-cyclic CMP P NG NG Cytidine-2’-monophosphate cytidine 2'-phosphate P G NG Inositol Hexaphosphate myo-inositol hexakisphosphate P G NG -Guanosine-2’,3’-cyclic monophosphate 2',3'-cyclic GMP P G NG -O-Phospho-L-Tyrosine O(4)-phospho-L-tyrosine P G NG -O-Phospho-L-Threonine O-phospho-L-threonine P G NG +Guanosine-2’,3’-cyclic monophosphate 2',3'-cyclic GMP P G G +O-Phospho-L-Tyrosine O(4)-phospho-L-tyrosine P G G +O-Phospho-L-Threonine O-phospho-L-threonine P G G Cytidine-3’-monophosphate P NG NG -D-3-Phospho-Glyceric Acid 3-phosphonato-D-glycerate(3-) P G NG +D-3-Phospho-Glyceric Acid 3-phosphonato-D-glycerate(3-) P G G Triethyl Phosphate P NG NG Phosphono Acetic Acid P NG NG Uridine-2’-monophosphate uridine 2'-phosphate P G NG -D-Glucose-1-Phosphate D-glucose 1-phosphate P G NG +D-Glucose-1-Phosphate D-glucose 1-phosphate P G G Uridine-3’-monophosphate 3'-UMP P G NG Cytidine-2’ ,3’-cyclic monophosphate 2',3'-cyclic CMP P G NG 2-Aminoethyl Phosphonic Acid P NG NG Uridine-2’,3’-cyclic monophosphate 2',3'-cyclic UMP P G NG -Adenosine-2’-monophosphate adenosine 2'-phosphate P G NG -Adenosine-3’-monophosphate 3'-AMP P G NG -Adenosine-2’,3’-cyclic monophosphate 2',3'-cyclic AMP P G NG +Adenosine-2’-monophosphate adenosine 2'-phosphate P G G +Adenosine-3’-monophosphate 3'-AMP P G G +Adenosine-2’,3’-cyclic monophosphate 2',3'-cyclic AMP P G G Hypophosphite P NG NG Guanosine-3’,5’-cyclic monophosphate 3',5'-cyclic GMP P NG NG Thymidine 3’,5’-cyclic monophosphate P NG NG -D-Mannose-1-Phosphate D-mannose 1-phosphate P G NG +D-Mannose-1-Phosphate D-mannose 1-phosphate P G G Urid ine-3’,5’-cyclic monophosphate P NG NG Methylene Diphosphonic Acid P G NG Adenosine-3’,5’-cyclic monophosphate 3',5'-cyclic AMP P NG NG -Adenosine-5’-monophosphate AMP P G NG +Adenosine-5’-monophosphate AMP P G G Sulfate sulphate S G G -L-Cysteine L-cysteine S NG NG +L-Cysteine L-cysteine S NG G Tetrathionate S NG NG Thiosulfate thiosulfate S G NG S-Methyl-L-Cysteine S G NG Hypotaurine S NG NG D-Methionine S NG NG L-Cysteinyl-Glycine L-cysteinylglycine S NG NG -L-Methionine L-methionine S G NG -Glutathione glutathione S G NG -N-Acetyl-D,L-Methionine N(alpha)-acetyl-L-methionine S G NG -L-Methionine Sulfoxide L-Methionine S-oxide S NG NG -Glycyl-L-Methionine Gly-Met S G NG +L-Methionine L-methionine S G G +Glutathione glutathione S G G +N-Acetyl-D,L-Methionine N(alpha)-acetyl-L-methionine S G G +L-Methionine Sulfoxide L-Methionine S-oxide S NG G +Glycyl-L-Methionine Gly-Met S G G Taurine tetrathionate S G NG D-Cysteine S NG NG Dithiophosphate S G NG Cystathionine S NG NG Cysteamine S NG NG -L-Cysteine Sulfinic Acid 3-sulfino-L-alanine S G NG +L-Cysteine Sulfinic Acid 3-sulfino-L-alanine S G G Thiophosphate S G NG Lanthionine S NG NG -N-Acetyl-L-Cysteine N-acetyl-L-cysteine S G NG +N-Acetyl-L-Cysteine N-acetyl-L-cysteine S G G Thiourea S G NG 1-Thio-β-D-Glucose S G NG Taurocholic Acid taurocholic acid S NG NG @@ -372,12 +372,12 @@ Butane Sulfonic Acid S G NG D,L-Lipoamide lipoamide S G NG L-Djenkolic Acid S NG NG Methane Sulfonic Acid S NG NG -L-Cysteic Acid L-cysteate S G NG +L-Cysteic Acid L-cysteate S G G p-Amino Benzene Sulfonic Acid S NG NG D,L-Ethionine S NG NG -2-Hydroxyethane Sulfonic Acid 2-hydroxyethane-1-sulfonate S G NG +2-Hydroxyethane Sulfonic Acid 2-hydroxyethane-1-sulfonate S G G Tetramethylene Sulfone S NG NG -L-Methionine Sulfone L-Methionine S-oxide S G NG +L-Methionine Sulfone L-Methionine S-oxide S G G Ethanol ethanol C G G D-Raffinose  raffinose C G G D-Cellobise C G NG diff --git a/ModelFiles/boundaryMets.txt b/ModelFiles/boundaryMets.txt index 09add12b..0877e1f8 100644 --- a/ModelFiles/boundaryMets.txt +++ b/ModelFiles/boundaryMets.txt @@ -168,3 +168,62 @@ s_3746[c] lipid backbone [cytoplasm] s_3747[c] lipid chain [cytoplasm] s_4074[e] cysteamine [extracellular] s_4124[e] methanol [extracellular] +s_4170[e] Ala-Gly [extracellular] +s_4137[e] 3-oxalomalate(3-) [extracellular] +s_4109[e] 6-O-alpha-D-glucopyranosyl-D-fructofuranose [extracellular] +s_4118[e] 5-dehydro-D-gluconate [extracellular] +s_4130[e] D-tagatose [extracellular] +s_4131[e] turanose [extracellular] +s_4150[e] D-glucose 6-phosphate [extracellular] +s_4140[e] alpha-maltotriose [extracellular] +s_4145[e] D-glucose 1-phosphate [extracellular] +s_4125[e] methyl alpha-D-glucopyranoside [extracellular] +s_4164[e] D-Glucosamine [extracellular] +s_4167[e] glycerone [extracellular] +s_4034[e] Ala-Gln [extracellular] +s_4168[e] Ala-Leu [extracellular] +s_4056[e] Gly-Gln [extracellular] +s_4050[e] Ala-His [extracellular] +s_4053[e] Gly-Asn [extracellular] +s_4037[e] Ala-Glu [extracellular] +s_4085[e] Gly-Met [extracellular] +s_4119[e] Ala-Asp [extracellular] +s_4059[e] Gly-Glu [extracellular] +s_4040[e] Ala-Thr [extracellular] +s_4143[e] Met-Ala [extracellular] +s_4166[e] L-citrulline [extracellular] +s_4080[e] 2-aminobutanoate [extracellular] +s_4158[e] choline phosphate [extracellular] +s_4049[e] glycerol 1-phosphate [extracellular] +s_4141[e] 2-phospho-D-glyceric acid [extracellular] +s_4148[e] GMP [extracellular] +s_4147[e] 3-phospho-serine [extracellular] +s_4078[e] O-phosphonatooxy-D-serine(2-) [extracellular] +s_4157[e] diphosphate [extracellular] +s_4099[e] triphosphate [extracellular] +s_4152[e] phosphoenolpyruvate [extracellular] +s_4093[e] N(omega)-phospho-L-arginine [extracellular] +s_4146[e] carbamoyl phosphate [extracellular] +s_4154[e] O-phosphoethanolamine [extracellular] +s_4075[e] cysteamine S-phosphate [extracellular] +s_4067[e] guanosine 2'-monophosphate [extracellular] +s_4063[e] glycerol 2-phosphate(2-) [extracellular] +s_4069[e] 3'-GMP [extracellular] +s_4070[e] 2-phosphoglycolate [extracellular] +s_4155[e] 6-phospho-D-gluconate [extracellular] +s_4153[e] D-mannose 6-phosphate [extracellular] +s_4095[e] 2',3'-cyclic GMP [extracellular] +s_4097[e] O(4)-phospho-L-tyrosine [extracellular] +s_4065[e] O-phospho-L-threonine [extracellular] +s_4142[e] 3-phosphonato-D-glycerate(3-) [extracellular] +s_4162[e] adenosine 2'-phosphate [extracellular] +s_4107[e] 3'-AMP [extracellular] +s_4161[e] 2',3'-cyclic AMP [extracellular] +s_4156[e] D-mannose 1-phosphate [extracellular] +s_4160[e] AMP [extracellular] +s_4135[e] N(alpha)-acetyl-L-methionine [extracellular] +s_4176[e] L-Methionine S-oxide [extracellular] +s_4105[e] 3-sulfino-L-alanine [extracellular] +s_4111[e] N-acetyl-L-cysteine [extracellular] +s_4139[e] L-cysteate [extracellular] +s_4116[e] 2-hydroxyethane-1-sulfonate [extracellular] diff --git a/ModelFiles/txt/yeastGEM.txt b/ModelFiles/txt/yeastGEM.txt index 197c329c..6feca733 100644 --- a/ModelFiles/txt/yeastGEM.txt +++ b/ModelFiles/txt/yeastGEM.txt @@ -3857,3 +3857,62 @@ r_4492 s_1198[c] + s_4181[c] -> s_0580[c] + s_0794[c] + s_1203[c] 0.00 1000 r_4493 s_4133[e] <=> s_4132[c] -1000.00 1000.00 0.00 r_4494 s_4124[e] <=> -1000.00 1000.00 0.00 r_4495 s_0389[c] + s_0803[c] -> s_0386[c] + s_1322[c] 0.00 1000.00 0.00 +r_4496 s_4170[e] -> 0.00 1000.00 0.00 +r_4497 s_4137[e] -> 0.00 1000.00 0.00 +r_4498 s_4109[e] -> 0.00 1000.00 0.00 +r_4499 s_4118[e] -> 0.00 1000.00 0.00 +r_4500 s_4130[e] -> 0.00 1000.00 0.00 +r_4501 s_4131[e] -> 0.00 1000.00 0.00 +r_4502 s_4150[e] -> 0.00 1000.00 0.00 +r_4503 s_4140[e] -> 0.00 1000.00 0.00 +r_4504 s_4145[e] -> 0.00 1000.00 0.00 +r_4505 s_4125[e] -> 0.00 1000.00 0.00 +r_4506 s_4164[e] -> 0.00 1000.00 0.00 +r_4507 s_4167[e] -> 0.00 1000.00 0.00 +r_4508 s_4034[e] -> 0.00 1000.00 0.00 +r_4509 s_4168[e] -> 0.00 1000.00 0.00 +r_4510 s_4056[e] -> 0.00 1000.00 0.00 +r_4511 s_4050[e] -> 0.00 1000.00 0.00 +r_4512 s_4053[e] -> 0.00 1000.00 0.00 +r_4513 s_4037[e] -> 0.00 1000.00 0.00 +r_4514 s_4085[e] -> 0.00 1000.00 0.00 +r_4515 s_4119[e] -> 0.00 1000.00 0.00 +r_4516 s_4059[e] -> 0.00 1000.00 0.00 +r_4517 s_4040[e] -> 0.00 1000.00 0.00 +r_4518 s_4143[e] -> 0.00 1000.00 0.00 +r_4519 s_4166[e] -> 0.00 1000.00 0.00 +r_4520 s_4080[e] -> 0.00 1000.00 0.00 +r_4521 s_4158[e] -> 0.00 1000.00 0.00 +r_4522 s_4049[e] -> 0.00 1000.00 0.00 +r_4523 s_4141[e] -> 0.00 1000.00 0.00 +r_4524 s_4148[e] -> 0.00 1000.00 0.00 +r_4525 s_4147[e] -> 0.00 1000.00 0.00 +r_4526 s_4078[e] -> 0.00 1000.00 0.00 +r_4527 s_4157[e] -> 0.00 1000.00 0.00 +r_4528 s_4099[e] -> 0.00 1000.00 0.00 +r_4529 s_4152[e] -> 0.00 1000.00 0.00 +r_4530 s_4093[e] -> 0.00 1000.00 0.00 +r_4531 s_4146[e] -> 0.00 1000.00 0.00 +r_4532 s_4154[e] -> 0.00 1000.00 0.00 +r_4533 s_4075[e] -> 0.00 1000.00 0.00 +r_4534 s_4067[e] -> 0.00 1000.00 0.00 +r_4535 s_4063[e] -> 0.00 1000.00 0.00 +r_4536 s_4069[e] -> 0.00 1000.00 0.00 +r_4537 s_4070[e] -> 0.00 1000.00 0.00 +r_4538 s_4155[e] -> 0.00 1000.00 0.00 +r_4539 s_4153[e] -> 0.00 1000.00 0.00 +r_4540 s_4095[e] -> 0.00 1000.00 0.00 +r_4541 s_4097[e] -> 0.00 1000.00 0.00 +r_4542 s_4065[e] -> 0.00 1000.00 0.00 +r_4543 s_4142[e] -> 0.00 1000.00 0.00 +r_4544 s_4162[e] -> 0.00 1000.00 0.00 +r_4545 s_4107[e] -> 0.00 1000.00 0.00 +r_4546 s_4161[e] -> 0.00 1000.00 0.00 +r_4547 s_4156[e] -> 0.00 1000.00 0.00 +r_4548 s_4160[e] -> 0.00 1000.00 0.00 +r_4549 s_4135[e] -> 0.00 1000.00 0.00 +r_4550 s_4176[e] -> 0.00 1000.00 0.00 +r_4551 s_4105[e] -> 0.00 1000.00 0.00 +r_4552 s_4111[e] -> 0.00 1000.00 0.00 +r_4553 s_4139[e] -> 0.00 1000.00 0.00 +r_4554 s_4116[e] -> 0.00 1000.00 0.00 diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index 22ad2841..4c3ed960 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -182640,6 +182640,1245 @@ + + + +

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+ @@ -187529,7 +188831,7 @@ - + @@ -187815,7 +189117,7 @@ - + @@ -187921,7 +189223,7 @@ - + @@ -187979,7 +189281,7 @@ - + @@ -188089,7 +189391,7 @@ - + @@ -188231,7 +189533,7 @@ - + @@ -188245,14 +189547,14 @@ - + - + @@ -188286,7 +189588,7 @@ - + @@ -188506,12 +189808,12 @@ - + - + @@ -188520,12 +189822,12 @@ - + - + @@ -188537,7 +189839,7 @@ - + @@ -188574,7 +189876,7 @@ - + @@ -188594,7 +189896,7 @@ - + @@ -188622,7 +189924,7 @@ - + @@ -188644,7 +189946,7 @@ - + @@ -188740,7 +190042,7 @@ - + @@ -188749,7 +190051,7 @@ - + diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index 4975054f..2eccb7d2 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -80891,6 +80891,537 @@ - annotation: !!omap - ec-code: 3.1.3.- - confidence_score: 0 + - !!omap + - id: r_4496 + - name: Exchange reaction, Ala-Gly [extracellular] + - metabolites: !!omap + - s_4170: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4497 + - name: Exchange reaction, 3-oxalomalate(3-) [extracellular] + - metabolites: !!omap + - s_4137: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4498 + - name: Exchange reaction, 6-O-alpha-D-glucopyranosyl-D-fructofuranose [extracellular] + - metabolites: !!omap + - s_4109: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4499 + - name: Exchange reaction, 5-dehydro-D-gluconate [extracellular] + - metabolites: !!omap + - s_4118: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4500 + - name: Exchange reaction, D-tagatose [extracellular] + - metabolites: !!omap + - s_4130: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4501 + - name: Exchange reaction, turanose [extracellular] + - metabolites: !!omap + - s_4131: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4502 + - name: Exchange reaction, D-glucose 6-phosphate [extracellular] + - metabolites: !!omap + - s_4150: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4503 + - name: Exchange reaction, alpha-maltotriose [extracellular] + - metabolites: !!omap + - s_4140: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4504 + - name: Exchange reaction, D-glucose 1-phosphate [extracellular] + - metabolites: !!omap + - s_4145: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4505 + - name: Exchange reaction, methyl alpha-D-glucopyranoside [extracellular] + - metabolites: !!omap + - s_4125: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4506 + - name: Exchange reaction, D-Glucosamine [extracellular] + - metabolites: !!omap + - s_4164: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4507 + - name: Exchange reaction, glycerone [extracellular] + - metabolites: !!omap + - s_4167: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4508 + - name: Exchange reaction, Ala-Gln [extracellular] + - metabolites: !!omap + - s_4034: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4509 + - name: Exchange reaction, Ala-Leu [extracellular] + - metabolites: !!omap + - s_4168: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4510 + - name: Exchange reaction, Gly-Gln [extracellular] + - metabolites: !!omap + - s_4056: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4511 + - name: Exchange reaction, Ala-His [extracellular] + - metabolites: !!omap + - s_4050: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4512 + - name: Exchange reaction, Gly-Asn [extracellular] + - metabolites: !!omap + - s_4053: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4513 + - name: Exchange reaction, Ala-Glu [extracellular] + - metabolites: !!omap + - s_4037: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4514 + - name: Exchange reaction, Gly-Met [extracellular] + - metabolites: !!omap + - s_4085: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4515 + - name: Exchange reaction, Ala-Asp [extracellular] + - metabolites: !!omap + - s_4119: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4516 + - name: Exchange reaction, Gly-Glu [extracellular] + - metabolites: !!omap + - s_4059: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4517 + - name: Exchange reaction, Ala-Thr [extracellular] + - metabolites: !!omap + - s_4040: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4518 + - name: Exchange reaction, Met-Ala [extracellular] + - metabolites: !!omap + - s_4143: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4519 + - name: Exchange reaction, L-citrulline [extracellular] + - metabolites: !!omap + - s_4166: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4520 + - name: Exchange reaction, 2-aminobutanoate [extracellular] + - metabolites: !!omap + - s_4080: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4521 + - name: Exchange reaction, choline phosphate [extracellular] + - metabolites: !!omap + - s_4158: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4522 + - name: Exchange reaction, glycerol 1-phosphate [extracellular] + - metabolites: !!omap + - s_4049: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4523 + - name: Exchange reaction, 2-phospho-D-glyceric acid [extracellular] + - metabolites: !!omap + - s_4141: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4524 + - name: Exchange reaction, GMP [extracellular] + - metabolites: !!omap + - s_4148: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4525 + - name: Exchange reaction, 3-phospho-serine [extracellular] + - metabolites: !!omap + - s_4147: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4526 + - name: Exchange reaction, O-phosphonatooxy-D-serine(2-) [extracellular] + - metabolites: !!omap + - s_4078: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4527 + - name: Exchange reaction, diphosphate [extracellular] + - metabolites: !!omap + - s_4157: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4528 + - name: Exchange reaction, triphosphate [extracellular] + - metabolites: !!omap + - s_4099: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4529 + - name: Exchange reaction, phosphoenolpyruvate [extracellular] + - metabolites: !!omap + - s_4152: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4530 + - name: Exchange reaction, N(omega)-phospho-L-arginine [extracellular] + - metabolites: !!omap + - s_4093: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4531 + - name: Exchange reaction, carbamoyl phosphate [extracellular] + - metabolites: !!omap + - s_4146: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4532 + - name: Exchange reaction, O-phosphoethanolamine [extracellular] + - metabolites: !!omap + - s_4154: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4533 + - name: Exchange reaction, cysteamine S-phosphate [extracellular] + - metabolites: !!omap + - s_4075: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4534 + - name: Exchange reaction, guanosine 2'-monophosphate [extracellular] + - metabolites: !!omap + - s_4067: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4535 + - name: Exchange reaction, glycerol 2-phosphate(2-) [extracellular] + - metabolites: !!omap + - s_4063: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4536 + - name: Exchange reaction, 3'-GMP [extracellular] + - metabolites: !!omap + - s_4069: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4537 + - name: Exchange reaction, 2-phosphoglycolate [extracellular] + - metabolites: !!omap + - s_4070: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4538 + - name: Exchange reaction, 6-phospho-D-gluconate [extracellular] + - metabolites: !!omap + - s_4155: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4539 + - name: Exchange reaction, D-mannose 6-phosphate [extracellular] + - metabolites: !!omap + - s_4153: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4540 + - name: Exchange reaction, 2',3'-cyclic GMP [extracellular] + - metabolites: !!omap + - s_4095: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4541 + - name: Exchange reaction, O(4)-phospho-L-tyrosine [extracellular] + - metabolites: !!omap + - s_4097: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4542 + - name: Exchange reaction, O-phospho-L-threonine [extracellular] + - metabolites: !!omap + - s_4065: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4543 + - name: Exchange reaction, 3-phosphonato-D-glycerate(3-) [extracellular] + - metabolites: !!omap + - s_4142: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4544 + - name: Exchange reaction, adenosine 2'-phosphate [extracellular] + - metabolites: !!omap + - s_4162: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4545 + - name: Exchange reaction, 3'-AMP [extracellular] + - metabolites: !!omap + - s_4107: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4546 + - name: Exchange reaction, 2',3'-cyclic AMP [extracellular] + - metabolites: !!omap + - s_4161: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4547 + - name: Exchange reaction, D-mannose 1-phosphate [extracellular] + - metabolites: !!omap + - s_4156: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4548 + - name: Exchange reaction, AMP [extracellular] + - metabolites: !!omap + - s_4160: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4549 + - name: Exchange reaction, N(alpha)-acetyl-L-methionine [extracellular] + - metabolites: !!omap + - s_4135: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4550 + - name: Exchange reaction, L-Methionine S-oxide [extracellular] + - metabolites: !!omap + - s_4176: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4551 + - name: Exchange reaction, 3-sulfino-L-alanine [extracellular] + - metabolites: !!omap + - s_4105: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4552 + - name: Exchange reaction, N-acetyl-L-cysteine [extracellular] + - metabolites: !!omap + - s_4111: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4553 + - name: Exchange reaction, L-cysteate [extracellular] + - metabolites: !!omap + - s_4139: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4554 + - name: Exchange reaction, 2-hydroxyethane-1-sulfonate [extracellular] + - metabolites: !!omap + - s_4116: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 - genes: - !!omap - id: Q0045 diff --git a/README.md b/README.md index b7c7951d..ff7e620a 100644 --- a/README.md +++ b/README.md @@ -16,7 +16,7 @@ This repository contains the current consensus genome-scale metabolic model of _ |Taxonomy | Template Model | Reactions | Metabolites| Genes | |:-------:|:--------------:|:---------:|:----------:|:-----:| -|_Saccharomyces cerevisiae_|[Yeast 7.6](https://sourceforge.net/projects/yeast/)|3858|2666|1133| +|_Saccharomyces cerevisiae_|[Yeast 7.6](https://sourceforge.net/projects/yeast/)|3917|2666|1133| This repository is administered by Benjamín J. Sánchez ([@BenjaSanchez](https://github.com/benjasanchez)), Division of Systems and Synthetic Biology, Department of Biology and Biological Engineering, Chalmers University of Technology. From 5d8e2a658c88d8126d461aa1687616df96ea1b23 Mon Sep 17 00:00:00 2001 From: FEIRANL Date: Sun, 26 Aug 2018 00:30:56 +0200 Subject: [PATCH 07/27] feat-rxnprop:change rxn reversibility Using code [~,metindex] = ismember('r_2075',model.rxns); model.lb(metindex) = -1000 [~,metindex] = ismember('r_0761',model.rxns); model.lb(metindex) = -1000 [~,metindex] = ismember('r_0103',model.rxns); model.lb(metindex) = -1000 [~,metindex] = ismember('r_0104',model.rxns); model.lb(metindex) = -1000 to change reversibility. r_0761 is refered to metacyc rxn: N-ACETYLTRANSFER-RXN r_0104 and r_0103 are refered to metacyc rxn: ACETYL-COA-ACETYLTRANSFER-RXN --- ModelFiles/txt/yeastGEM.txt | 8 ++++---- ModelFiles/xml/yeastGEM.xml | 8 ++++---- ModelFiles/yml/yeastGEM.yml | 8 ++++---- 3 files changed, 12 insertions(+), 12 deletions(-) diff --git a/ModelFiles/txt/yeastGEM.txt b/ModelFiles/txt/yeastGEM.txt index 6feca733..6a1d1b0f 100644 --- a/ModelFiles/txt/yeastGEM.txt +++ b/ModelFiles/txt/yeastGEM.txt @@ -83,8 +83,8 @@ r_0099 s_0376[m] + s_1845[m] <=> s_0372[m] + s_0532[m] YKL192C -1000.00 1000.0 r_0100 s_0250[p] + s_0534[p] -> s_0378[p] + s_1305[p] YIL160C 0.00 1000.00 0.00 r_0101 s_0243[p] + s_0534[p] -> s_0378[p] + s_1482[p] YIL160C 0.00 1000.00 0.00 r_0102 s_0253[p] + s_0534[p] -> s_0378[p] + s_1179[p] YIL160C 0.00 1000.00 0.00 -r_0103 2 s_0373[c] -> s_0367[c] + s_0529[c] YPL028W 0.00 1000.00 0.00 -r_0104 2 s_0376[m] -> s_0370[m] + s_0532[m] YPL028W 0.00 1000.00 0.00 +r_0103 2 s_0373[c] <=> s_0367[c] + s_0529[c] YPL028W -1000.00 1000.00 0.00 +r_0104 2 s_0376[m] <=> s_0370[m] + s_0532[m] YPL028W -1000.00 1000.00 0.00 r_0105 s_0257[p] + s_0534[p] -> s_0378[p] + s_1076[p] YIL160C 0.00 1000.00 0.00 r_0106 s_0239[p] + s_0534[p] -> s_0378[p] + s_1258[p] YIL160C 0.00 1000.00 0.00 r_0107 s_0247[p] + s_0534[p] -> s_0378[p] + s_0605[p] YIL160C 0.00 1000.00 0.00 @@ -609,7 +609,7 @@ r_0757 s_0126[c] + s_0803[c] -> s_1153[c] + s_1322[c] ( YDR287W or YHR046C ) r_0758 s_0568[c] -> s_0126[c] YJL153C 0.00 1000.00 0.00 r_0759 s_0799[m] + s_1191[m] + s_1214[m] -> s_0145[m] + s_1210[m] + s_1326[m] YER069W 0.00 1000.00 0.00 r_0760 s_0373[c] + s_0412[c] <=> s_0529[c] + s_0794[c] + s_1190[c] YFL017C -1000.00 1000.00 0.00 -r_0761 s_0376[m] + s_0993[m] -> s_0532[m] + s_0799[m] + s_1192[m] ( YJL071W or YMR062C ) 0.00 1000.00 0.00 +r_0761 s_0376[m] + s_0993[m] <=> s_0532[m] + s_0799[m] + s_1192[m] ( YJL071W or YMR062C ) -1000.00 1000.00 0.00 r_0762 s_0803[c] + s_1195[c] -> s_0722[c] + s_0794[c] + s_1020[c] YDR428C 0.00 1000.00 0.00 r_0763 s_0794[c] + 2 s_1196[c] + s_1212[c] -> s_1185[c] + s_1207[c] ( YDR402C and YDR403W ) 0.00 1000.00 0.00 r_0764 s_0809[p] + s_1202[p] -> s_0426[p] + 2 s_0801[p] + s_1228[p] YGL067W 0.00 1000.00 0.00 @@ -2877,7 +2877,7 @@ r_2071 s_0581[c] + s_0794[c] + s_0981[c] + s_1003[c] + s_1233[c] -> s_0293[c] + r_2072 s_1045[c] -> s_1047[m] 0.00 1000.00 0.00 r_2073 s_1494[e] -> 0.00 1000.00 0.00 r_2074 s_0434[c] + s_1493[c] -> s_0394[c] + s_0649[c] + s_0794[c] 0.00 1000.00 0.00 -r_2075 s_1494[e] -> s_1493[c] 0.00 1000.00 0.00 +r_2075 s_1494[e] <=> s_1493[c] -1000.00 1000.00 0.00 r_2080 s_1520[c] <=> s_1522[v] -1000.00 1000.00 0.00 r_2082 s_1048[c] -> s_1050[m] 0.00 1000.00 0.00 r_2083 s_1530[e] -> 0.00 1000.00 0.00 diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index 4c3ed960..821f6690 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -53136,7 +53136,7 @@ - +

Confidence Level: 2

@@ -53169,7 +53169,7 @@ - +

Confidence Level: 2

@@ -74308,7 +74308,7 @@ - +

Confidence Level: 2

@@ -156085,7 +156085,7 @@ - +

Confidence Level: 0

diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index 2eccb7d2..cd8245a3 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -23702,7 +23702,7 @@ - s_0367: 1 - s_0373: -2 - s_0529: 1 - - lower_bound: 0 + - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YPL028W - subsystem: @@ -23730,7 +23730,7 @@ - s_0370: 1 - s_0376: -2 - s_0532: 1 - - lower_bound: 0 + - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YPL028W - subsystem: @@ -34217,7 +34217,7 @@ - s_0799: 1 - s_0993: -1 - s_1192: 1 - - lower_bound: 0 + - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YJL071W or YMR062C - subsystem: @@ -45197,7 +45197,7 @@ - metabolites: !!omap - s_1493: 1 - s_1494: -1 - - lower_bound: 0 + - lower_bound: -1000 - upper_bound: 1000 - confidence_score: 0 - !!omap From fdb66e07ea937d465d353747dd8c0606ef6ad818 Mon Sep 17 00:00:00 2001 From: FEIRANL Date: Sun, 26 Aug 2018 00:37:11 +0200 Subject: [PATCH 08/27] feat-data:Update model prediction Running SubstrateUsage again to update model prediction and also adding extra exchange reactions for those substrates that can be utilized --- .../modelCuration/Biolog_Substrate.tsv | 24 +- ModelFiles/boundaryMets.txt | 11 + ModelFiles/txt/yeastGEM.txt | 11 + ModelFiles/xml/yeastGEM.xml | 242 ++++++++++++++++++ ModelFiles/yml/yeastGEM.yml | 99 +++++++ README.md | 2 +- 6 files changed, 376 insertions(+), 13 deletions(-) diff --git a/ComplementaryData/modelCuration/Biolog_Substrate.tsv b/ComplementaryData/modelCuration/Biolog_Substrate.tsv index 09b4bcfc..940e5929 100644 --- a/ComplementaryData/modelCuration/Biolog_Substrate.tsv +++ b/ComplementaryData/modelCuration/Biolog_Substrate.tsv @@ -57,7 +57,7 @@ L-Isoleucine L-isoleucine C NG NG α-Hydroxy Butyric Acid C NG NG α-Keto Valeric Acid C NG NG 3-0-β-D Galacto-pyranosyl-D-Arabinose C NG NG -Acetoacetic Acid acetoacetate C G NG +Acetoacetic Acid acetoacetate C G G Glyoxylic Acid glyoxylate C NG G Tween 20 C NG NG Palatinose 6-O-alpha-D-glucopyranosyl-D-fructofuranose C G G @@ -78,7 +78,7 @@ Mucic Acid C NG NG 3-Methyl Glucose C NG NG D-Fructose-6-Phosphate D-fructose 6-phosphate C NG NG D-Tagatose D-tagatose C G G -N-Acetyl-L-Glutamic Acid N-acetyl-L-glutamate C NG NG +N-Acetyl-L-Glutamic Acid N-acetyl-L-glutamate C NG G Turanose turanose C G G D-Glucose-6-Phosphate D-glucose 6-phosphate C NG G L-Sorbose L-sorbose C NG NG @@ -263,7 +263,7 @@ L-Phenylalanine L-phenylalanine N G G Biuret N NG NG N-Butylamine N NG NG N-Acetyl-D-Galactosamine N NG NG -N-Acetyl-D ,L-Glutamic Acid N-acetyl-L-glutamate N G NG +N-Acetyl-D ,L-Glutamic Acid N-acetyl-L-glutamate N G G N-Acetyl-D-Mannosamine N NG NG L-Homoserine L-homoserine N G G Adenine adenine N NG G @@ -295,8 +295,8 @@ Phosphate phosphate P G G Pyrophosphate diphosphate P G G Thiophosphate P G NG Tripolyphosphate triphosphate P G G -Uridine-5’-monophosphate UMP P G NG -Cytidine-5’-monophosphate CMP P G NG +Uridine-5’-monophosphate UMP P G G +Cytidine-5’-monophosphate CMP P G G Phosphoenol Pyruvate phosphoenolpyruvate P G G Trimetaphosphate P G NG Phospho-L-Arginine N(omega)-phospho-L-arginine P G G @@ -305,8 +305,8 @@ O-Phosphoryl-Ethanolamine O-phosphoethanolamine P G G D-Glucosamine-6-Phosphate alpha-D-glucosamine 6-phosphate P G G Phosphocreatine N-phosphocreatine P G NG Dithiophosphate P G NG -Thymidine-5’-monophosphate thymidine 5'-monophosphate P G NG -Thymidine-3 ’-monophosphate thymidine 3'-monophosphate P G NG +Thymidine-5’-monophosphate thymidine 5'-monophosphate P G G +Thymidine-3 ’-monophosphate thymidine 3'-monophosphate P G G Cysteamine-S-Phosphate cysteamine S-phosphate P G G 2-Deoxy-D-Glucose 6-Phosphate 2-deoxy-D-glucose 6-phosphate P NG NG Guanosine-2’-monophosphate guanosine 2'-monophosphate P G G @@ -317,7 +317,7 @@ Phospho-Glycolic Acid 2-phosphoglycolate P G G 6-Phospho-Gluconic Acid 6-phospho-D-gluconate P G G D-Mannose-6-Phosphate D-mannose 6-phosphate P G G Cytidine-3’,5’-cyclic monophosphate 3',5'-cyclic CMP P NG NG -Cytidine-2’-monophosphate cytidine 2'-phosphate P G NG +Cytidine-2’-monophosphate cytidine 2'-phosphate P G G Inositol Hexaphosphate myo-inositol hexakisphosphate P G NG Guanosine-2’,3’-cyclic monophosphate 2',3'-cyclic GMP P G G O-Phospho-L-Tyrosine O(4)-phospho-L-tyrosine P G G @@ -326,12 +326,12 @@ Cytidine-3’-monophosphate P NG NG D-3-Phospho-Glyceric Acid 3-phosphonato-D-glycerate(3-) P G G Triethyl Phosphate P NG NG Phosphono Acetic Acid P NG NG -Uridine-2’-monophosphate uridine 2'-phosphate P G NG +Uridine-2’-monophosphate uridine 2'-phosphate P G G D-Glucose-1-Phosphate D-glucose 1-phosphate P G G -Uridine-3’-monophosphate 3'-UMP P G NG -Cytidine-2’ ,3’-cyclic monophosphate 2',3'-cyclic CMP P G NG +Uridine-3’-monophosphate 3'-UMP P G G +Cytidine-2’ ,3’-cyclic monophosphate 2',3'-cyclic CMP P G G 2-Aminoethyl Phosphonic Acid P NG NG -Uridine-2’,3’-cyclic monophosphate 2',3'-cyclic UMP P G NG +Uridine-2’,3’-cyclic monophosphate 2',3'-cyclic UMP P G G Adenosine-2’-monophosphate adenosine 2'-phosphate P G G Adenosine-3’-monophosphate 3'-AMP P G G Adenosine-2’,3’-cyclic monophosphate 2',3'-cyclic AMP P G G diff --git a/ModelFiles/boundaryMets.txt b/ModelFiles/boundaryMets.txt index 0877e1f8..4c031f7b 100644 --- a/ModelFiles/boundaryMets.txt +++ b/ModelFiles/boundaryMets.txt @@ -227,3 +227,14 @@ s_4105[e] 3-sulfino-L-alanine [extracellular] s_4111[e] N-acetyl-L-cysteine [extracellular] s_4139[e] L-cysteate [extracellular] s_4116[e] 2-hydroxyethane-1-sulfonate [extracellular] +s_4133[e] acetoacetate [extracellular] +s_4172[e] N-acetyl-L-glutamate [extracellular] +s_4151[e] UMP [extracellular] +s_4163[e] CMP [extracellular] +s_4047[e] thymidine 5'-monophosphate [extracellular] +s_4045[e] thymidine 3'-monophosphate [extracellular] +s_4101[e] cytidine 2'-phosphate [extracellular] +s_4082[e] uridine 2'-phosphate [extracellular] +s_4084[e] 3'-UMP [extracellular] +s_4127[e] 2',3'-cyclic CMP [extracellular] +s_4103[e] 2',3'-cyclic UMP [extracellular] diff --git a/ModelFiles/txt/yeastGEM.txt b/ModelFiles/txt/yeastGEM.txt index 6a1d1b0f..8a3abc6c 100644 --- a/ModelFiles/txt/yeastGEM.txt +++ b/ModelFiles/txt/yeastGEM.txt @@ -3916,3 +3916,14 @@ r_4551 s_4105[e] -> 0.00 1000.00 0.00 r_4552 s_4111[e] -> 0.00 1000.00 0.00 r_4553 s_4139[e] -> 0.00 1000.00 0.00 r_4554 s_4116[e] -> 0.00 1000.00 0.00 +r_4555 s_4133[e] -> 0.00 1000.00 0.00 +r_4556 s_4172[e] -> 0.00 1000.00 0.00 +r_4557 s_4151[e] -> 0.00 1000.00 0.00 +r_4558 s_4163[e] -> 0.00 1000.00 0.00 +r_4559 s_4047[e] -> 0.00 1000.00 0.00 +r_4560 s_4045[e] -> 0.00 1000.00 0.00 +r_4561 s_4101[e] -> 0.00 1000.00 0.00 +r_4562 s_4082[e] -> 0.00 1000.00 0.00 +r_4563 s_4084[e] -> 0.00 1000.00 0.00 +r_4564 s_4127[e] -> 0.00 1000.00 0.00 +r_4565 s_4103[e] -> 0.00 1000.00 0.00 diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index 821f6690..876bddaf 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -183879,6 +183879,237 @@ + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + @@ -185084,6 +185315,17 @@ + + + + + + + + + + + diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index cd8245a3..c105a4d7 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -81422,6 +81422,105 @@ - upper_bound: 1000 - subsystem: Exchange - confidence_score: 0 + - !!omap + - id: r_4555 + - name: Exchange reaction, acetoacetate [extracellular] + - metabolites: !!omap + - s_4133: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4556 + - name: Exchange reaction, N-acetyl-L-glutamate [extracellular] + - metabolites: !!omap + - s_4172: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4557 + - name: Exchange reaction, UMP [extracellular] + - metabolites: !!omap + - s_4151: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4558 + - name: Exchange reaction, CMP [extracellular] + - metabolites: !!omap + - s_4163: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4559 + - name: Exchange reaction, thymidine 5'-monophosphate [extracellular] + - metabolites: !!omap + - s_4047: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4560 + - name: Exchange reaction, thymidine 3'-monophosphate [extracellular] + - metabolites: !!omap + - s_4045: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4561 + - name: Exchange reaction, cytidine 2'-phosphate [extracellular] + - metabolites: !!omap + - s_4101: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4562 + - name: Exchange reaction, uridine 2'-phosphate [extracellular] + - metabolites: !!omap + - s_4082: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4563 + - name: Exchange reaction, 3'-UMP [extracellular] + - metabolites: !!omap + - s_4084: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4564 + - name: Exchange reaction, 2',3'-cyclic CMP [extracellular] + - metabolites: !!omap + - s_4127: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 + - !!omap + - id: r_4565 + - name: Exchange reaction, 2',3'-cyclic UMP [extracellular] + - metabolites: !!omap + - s_4103: -1 + - lower_bound: 0 + - upper_bound: 1000 + - subsystem: Exchange + - confidence_score: 0 - genes: - !!omap - id: Q0045 diff --git a/README.md b/README.md index ff7e620a..33d718fd 100644 --- a/README.md +++ b/README.md @@ -16,7 +16,7 @@ This repository contains the current consensus genome-scale metabolic model of _ |Taxonomy | Template Model | Reactions | Metabolites| Genes | |:-------:|:--------------:|:---------:|:----------:|:-----:| -|_Saccharomyces cerevisiae_|[Yeast 7.6](https://sourceforge.net/projects/yeast/)|3917|2666|1133| +|_Saccharomyces cerevisiae_|[Yeast 7.6](https://sourceforge.net/projects/yeast/)|3928|2666|1133| This repository is administered by Benjamín J. Sánchez ([@BenjaSanchez](https://github.com/benjasanchez)), Division of Systems and Synthetic Biology, Department of Biology and Biological Engineering, Chalmers University of Technology. From 2fc5837c8eb232d52c5144dbde64bd6d577b5d4f Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Sun, 26 Aug 2018 19:32:04 +0200 Subject: [PATCH 09/27] style: functions + data * comply with repo format * spelling errors corrected * grRules deltion avoided * cd properly --- .../modelCuration/Biolog_Substrate.tsv | 2 +- .../modelCuration/SubstrateUsage.m | 175 +++++++----------- .../modelCuration/addBiologRxnToGEM.m | 109 +++++------ ModelFiles/dependencies.txt | 2 +- 4 files changed, 118 insertions(+), 170 deletions(-) diff --git a/ComplementaryData/modelCuration/Biolog_Substrate.tsv b/ComplementaryData/modelCuration/Biolog_Substrate.tsv index 940e5929..df385562 100644 --- a/ComplementaryData/modelCuration/Biolog_Substrate.tsv +++ b/ComplementaryData/modelCuration/Biolog_Substrate.tsv @@ -1,4 +1,4 @@ -Subtrate Name_in_Model Substrate_type Growth_Biolog Growth_Model +Substrate Name_in_Model Substrate_type Growth_Biolog Growth_Model L-Malic Acid (S)-malate C NG G L-Glutamic Acid L-glutamate C NG G Thymidine thymidine C NG NG diff --git a/ComplementaryScripts/modelCuration/SubstrateUsage.m b/ComplementaryScripts/modelCuration/SubstrateUsage.m index 1293fa2e..7d826a22 100644 --- a/ComplementaryScripts/modelCuration/SubstrateUsage.m +++ b/ComplementaryScripts/modelCuration/SubstrateUsage.m @@ -1,98 +1,75 @@ -%This code is developed to automatically add -%exchange reactions for newmets and check whether it can be used as solo -%substrate. - -% Adds exchange reactions reactions -% -% USAGE: -% -% [metsCanBeUlitilized,metsCannotBeUltilized,newmodel] = substrateusage(model,biomass,substratelist,substratetype) -% -% INPUTS: -% model: Cobra model structure -% biomass: biomass reaction rxn ID +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% +% SubstrateUsage % +% Automatically adds exchange reactions for every metabolite in +% ComplementaryData/modelCuration/Biolog_substrate.tsv and checks whether +% it can be used as a "solo" substrate. % -% OPTIONAL INPUTS: -% substratelist: substrates list -% substratetype: 'N'|'C'|'P'|'S' -% -% OUTPUT: -% newModel: COBRA model with added reactions -% -% .. Author: - Feiran Li 2018.05.04 -% As for the reference of Biolog_substrate_type.tsv, please find detailed information in the /ComplementaryData/experiment/Biolog.tsv -% NOTE: -% COBRA required. -% -% Feiran Li - +% NOTE: requires COBRA +% +% Feiran Li 2018-08-25 +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% - -% Load model +% Load model: cd .. model = loadYeastModel; -%%%%%substrateusage%%%%%%%%%%%%%%%%%%%%%%%%%%%% +% Load data: fid2 = fopen('../ComplementaryData/modelCuration/Biolog_substrate.tsv'); substrate = textscan(fid2,'%s %s %s %s %s %s','Delimiter','\t','HeaderLines',1); SubBiologName = substrate{1}; -SubModelName = substrate{2}; -Subtype = substrate{3}; -BiologUsage = substrate{4}; +SubModelName = substrate{2}; +Subtype = substrate{3}; +BiologUsage = substrate{4}; fclose(fid2); - -ExchRxn = ''; -TransRxn = ''; -GapfillMets = ''; +% Main loop: +cd otherChanges +ExchRxn = ''; +TransRxn = ''; +GapfillMets = ''; TransEotherfillMets = ''; -TransECfillMets = ''; -FBAresult = ''; +TransECfillMets = ''; +FBAresult = ''; for i = 1:length(SubBiologName) newModel = model; if ~isequal(SubModelName{i},'') - metE = strcat(SubModelName{i},' [extracellular]'); metC = strcat(SubModelName{i},' [cytoplasm]'); - [tmp,metEOrd] = ismember(metE,newModel.metNames); - [tmp,metCOrd] = ismember(metC,newModel.metNames); + [~,metEOrd] = ismember(metE,newModel.metNames); + [~,metCOrd] = ismember(metC,newModel.metNames); %check whther exchange reaction for this met exists duplicateE = find(sum(newModel.S ~= 0, 1) == 1 & any(newModel.S == -1, 1) & any(newModel.S(metEOrd(metEOrd~=0), :), 1)); if ~isempty(duplicateE) warning(['Model already has the same exchange reaction you tried to add: ', newModel.rxns{duplicateE}]); - %ExchRxn = [ExchRxn;newModel.metNames(metEOrd),newModel.rxns{duplicateE}]; ExchRxn = newModel.rxns(duplicateE); else if metEOrd == 0 newID = getNewIndex(newModel.mets); metE_temp_ID = strcat('s_',newID,'[e]'); newModel = addMetabolite(newModel,metE_temp_ID, ... - 'metName',metE); - %adding exchange rxn for this metE + 'metName',metE); + %adding exchange rxn for this metE newID = getNewIndex(newModel.rxns); [newModel,rxnIDexists] = addReaction(newModel,['r_' newID],... - 'reactionName',['Exchange reaction, ',metE],... - 'metaboliteList',cellstr(metE_temp_ID),'stoichCoeffList',-1,... - 'lowerBound',0, 'upperBound',1000, 'subSystem', 'Exchange', 'checkDuplicate', false); - [tmp,metEOrd] = ismember(metE,newModel.metNames); - % ExchRxn=[ExchRxn;newModel.metNames(metEOrd),['r_' newID]]; - ExchRxn=['r_' newID]; - else - %adding exchange rxn for this metE + 'reactionName',['Exchange reaction, ',metE],... + 'metaboliteList',cellstr(metE_temp_ID),'stoichCoeffList',-1,... + 'lowerBound',0, 'upperBound',1000, 'subSystem', 'Exchange', 'checkDuplicate', false); + [~,metEOrd] = ismember(metE,newModel.metNames); + ExchRxn=['r_' newID]; + else + %adding exchange rxn for this metE newID = getNewIndex(newModel.rxns); [newModel,rxnIDexists] = addReaction(newModel,['r_' newID],... - 'reactionName',['Exchange reaction, ',metE],... - 'metaboliteList',newModel.mets(metEOrd),'stoichCoeffList',-1,... - 'lowerBound',0, 'upperBound',1000, 'subSystem', 'Exchange', 'checkDuplicate', false); - [tmp,metEOrd] = ismember(metE,newModel.metNames); + 'reactionName',['Exchange reaction, ',metE],... + 'metaboliteList',newModel.mets(metEOrd),'stoichCoeffList',-1,... + 'lowerBound',0, 'upperBound',1000, 'subSystem', 'Exchange', 'checkDuplicate', false); + [~,metEOrd] = ismember(metE,newModel.metNames); ExchRxn=['r_' newID]; end end - - - - %model prediction + + % Model prediction: newModel_test = newModel; exchangeRxns = findExcRxns(newModel_test); newModel_test.lb(exchangeRxns) = 0; @@ -102,7 +79,7 @@ 'r_1861'; ... % iron for test of expanded biomass def; 'r_1832'; ... % hydrogen exchange; }; - glcExchange = {'r_1714'};% D-glucose exchange' + glcExchange = {'r_1714'};% D-glucose exchange' amoExchange = {'r_1654'}; % 'ammonium exchange' phoExchange = {'r_2005'}; % 'phosphate exchange' sulExchange = {'r_2060'}; % 'phosphate exchange' @@ -146,64 +123,46 @@ newModel_test.lb(SubRxnIndexes)=-1000; end sol = optimizeCbModel(newModel_test); - if sol.obj > 0.000001 - model = newModel; - fprintf(metE,'can be used as solo substrate\n'); - FBAresult = [FBAresult;SubBiologName(i,1),SubModelName(i,1),Subtype(i,1),BiologUsage(i,1),'G']; - else - FBAresult = [FBAresult;SubBiologName(i,1),SubModelName(i,1),Subtype(i,1),BiologUsage(i,1),'NG']; - if strcmp(BiologUsage(i,1),'G') - fprintf(metE,'cannot be used as solo substrate, pathways need to be manually checked\n'); - if numel(find(newModel_test.S(metEOrd,:))) < 2 && metCOrd~=0 %metE appear only once without metC - warning(['Transport reaction should be added for:', newModel_test.metNames{metEOrd}]) - TransECfillMets = [TransECfillMets;newModel_test.metNames(metEOrd)]; - elseif numel(find(newModel_test.S(metEOrd,:))) < 2 && metCOrd ==0 %metE appear only once without metC - S = regexp(newModel_test.metNames{metEOrd}, ' [', 'split'); - met_temp = char(S(1)); - metEMapping = find(strncmp(met_temp,model.metNames,length(met_temp))); - if isempty(metEMapping) - warning(['mets only appear once, fill the gap for mets:', newModel_test.metNames{metEOrd}]) - GapfillMets = [GapfillMets;newModel_test.metNames(metEOrd)]; - else - TransEotherfillMets = [TransEotherfillMets;newModel_test.metNames(metEOrd);model.metNames(metEMapping)]; - end + if sol.obj > 0.000001 + model = newModel; + fprintf(metE,'can be used as solo substrate\n'); + FBAresult = [FBAresult;SubBiologName(i,1),SubModelName(i,1),Subtype(i,1),BiologUsage(i,1),'G']; + else + FBAresult = [FBAresult;SubBiologName(i,1),SubModelName(i,1),Subtype(i,1),BiologUsage(i,1),'NG']; + if strcmp(BiologUsage(i,1),'G') + fprintf(metE,'cannot be used as solo substrate, pathways need to be manually checked\n'); + if numel(find(newModel_test.S(metEOrd,:))) < 2 && metCOrd~=0 %metE appear only once without metC + warning(['Transport reaction should be added for:', newModel_test.metNames{metEOrd}]) + TransECfillMets = [TransECfillMets;newModel_test.metNames(metEOrd)]; + elseif numel(find(newModel_test.S(metEOrd,:))) < 2 && metCOrd ==0 %metE appear only once without metC + S = regexp(newModel_test.metNames{metEOrd}, ' [', 'split'); + met_temp = char(S(1)); + metEMapping = find(strncmp(met_temp,model.metNames,length(met_temp))); + if isempty(metEMapping) + warning(['mets only appear once, fill the gap for mets:', newModel_test.metNames{metEOrd}]) + GapfillMets = [GapfillMets;newModel_test.metNames(metEOrd)]; + else + TransEotherfillMets = [TransEotherfillMets;newModel_test.metNames(metEOrd);model.metNames(metEMapping)]; end end - end + end + end else - FBAresult = [FBAresult;SubBiologName(i,1),SubModelName(i,1),Subtype(i,1),BiologUsage(i,1),'NG']; + FBAresult = [FBAresult;SubBiologName(i,1),SubModelName(i,1),Subtype(i,1),BiologUsage(i,1),'NG']; end end - - - - - %save results +% Update results from model: +cd .. fid2 = fopen('../ComplementaryData/modelCuration/Biolog_substrate.tsv','w'); formatSpec = '%s\t%s\t%s\t%s\t%s\n'; -fprintf(fid2,formatSpec,'Subtrate','Name_in_Model','Substrate_type','Growth_Biolog','Growth_Model'); +fprintf(fid2,formatSpec,'Substrate','Name_in_Model','Substrate_type','Growth_Biolog','Growth_Model'); for i = 1:length(FBAresult) fprintf(fid2,formatSpec,char(FBAresult(i,1)),char(FBAresult(i,2)),char(FBAresult(i,3)),char(FBAresult(i,4)),char(FBAresult(i,5))); - end -%save model -%model = newModel; -model = rmfield(model,'grRules'); -cd .. +% Save model: saveYeastModel(model) cd modelCuration - - - - - - - - - - - - \ No newline at end of file +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% diff --git a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m index 48ea5ea6..d3172960 100644 --- a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m +++ b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m @@ -1,29 +1,30 @@ -% This Function is for adding Biolog related metabolites/reactions into model. -% Add rxns and metabolites based on Biolog results, see -% Biolog_substrate_type.tsv for substrates that can be ultilized -% Input: model, Biolog_substrate_type.tsv,Biolog_newRxnProp.tsv,Biolog_newRxnMet.tsv. -% As for the reference of new genes and reactions related, please find detailed information in the /ComplementaryData/experiment/Biolog_experiment.tsv -% NOTE: changeGeneAssociation.m is a function from cobra -% Extract model info from .tsv format. -% Before run the codes below, the file should be manually editted. -% COBRA required. -% New reaction should be in .tsv format. +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% +% addBiologRxnToGEM +% Adds rxns and metabolites based on Biolog results, see +% Biolog_substrate_type.tsv for substrates that can be utilized. +% Input: model, Biolog_substrate_type.tsv, Biolog_newRxnProp.tsv, +% Biolog_newRxnMet.tsv. % -% Feiran Li -%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%newreaction: -% Load model +% NOTE: changeGeneAssociation.m is a function from COBRA +% +% Feiran Li 2018-08-25 +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% + +% Load model: cd .. model = loadYeastModel; +% Load stoichiometry data: fid = fopen('../ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv'); newreaction = textscan(fid,'%s %s %s %s %s','Delimiter','\t','HeaderLines',1); -matrix.rxnIDs = newreaction{1}; -matrix.metcoef = cellfun(@str2num, newreaction{2}); -matrix.metIDs = newreaction{3}; +matrix.rxnIDs = newreaction{1}; +matrix.metcoef = cellfun(@str2num, newreaction{2}); +matrix.metIDs = newreaction{3}; matrix.mettype = newreaction{4}; matrix.metcompartments = newreaction{5}; fclose(fid); -%rev and GPR + +% Load rxn properties data: fid = fopen('../ComplementaryData/modelCuration/Biolog_newRxnProp.tsv','r'); rev = textscan(fid,'%s %s %s %s %s %s %s','Delimiter','\t','HeaderLines',1); newrxn.ID = rev{1}; @@ -31,24 +32,20 @@ newrxn.GPR = rev{3}; newrxn.rxnNames = rev{4}; newrxn.rxnECNumbers = rev{5}; -newrxn.rxnKEGGID = rev{6}; -newrxn.rxnNotes = rev{7}; +newrxn.rxnKEGGID = rev{6}; +newrxn.rxnNotes = rev{7}; fclose(fid); -%change coefficient -%matrix.metcoef_temp = cellfun(@str2num, matrix.metcoef); +% Change coefficients for reactants: for i=1:length(matrix.rxnIDs) - if strcmp(matrix.mettype(i),'reactant') - matrix.metcoef(i) = matrix.metcoef(i)*-1 - %matrix.metcoef_temp(i) = matrix.metcoef_temp(i)*-1 - end + if strcmp(matrix.mettype(i),'reactant') + matrix.metcoef(i) = matrix.metcoef(i)*-1; + end end -%matrix.metcoef = num2cell(matrix.metcoef_temp); - -%change compatments +% Change compartments: CONValldata = cat(2,model.compNames,model.comps); -lbracket = ' [' ;% space +lbracket = ' [' ; llbracket = '['; rbrackets = ']'; space = ' '; @@ -69,10 +66,8 @@ matrix.Newcomps(i) = strcat(llbracket,matrix.Newcomps(i),rbrackets); end - - -%mapping mets to model.metnames, get s_ index for new mets -cd modelCuration/ +% Map mets to model.metnames, get s_index for new mets: +cd otherChanges for j = 1:length(matrix.metnames) [~,metindex] = ismember(matrix.metnames(j),model.metNames); if metindex ~= 0 @@ -81,12 +76,11 @@ newID = getNewIndex(model.mets); matrix.mets(j) = strcat('s_',newID,matrix.Newcomps(j)); model = addMetabolite(model,char(matrix.mets(j)), ... - 'metName',matrix.metnames(j)); + 'metName',matrix.metnames(j)); end end - -% add met annotation +% Add metabolite data: fid = fopen('../../ComplementaryData/modelCuration/Biolog_newRxnMetAnnotation.tsv'); newmet_annot = textscan(fid,'%s %s %s %s %s %s %s','Delimiter','\t','HeaderLines',1); newmet.metNames = newmet_annot{1}; @@ -96,7 +90,6 @@ newmet.metChEBIID = newmet_annot{6}; newmet.metNotes = newmet_annot{7}; fclose(fid); - for i = 1:length(newmet.metNames) [~,metID] = ismember(newmet.metNames(i),model.metNames); if metID ~= 0 @@ -108,36 +101,32 @@ end end -%add new reactions according to rev ID. Met Coef need to be in the column, -%not a row. Coef should be double, which was converted at the import -%section. - EnergyResults = {}; +% Add new reactions according to rev ID: Met Coef needs to be a column, not +% a row. Coef should be a double, which was converted at the import section +EnergyResults = {}; MassChargeresults = {}; RedoxResults = {}; for i = 1:length(newrxn.ID) - cd ../otherchanges - newID = getNewIndex(model.rxns); - cd ../modelCuration - j = find(strcmp(matrix.rxnIDs,newrxn.ID{i})); - Met = matrix.mets(j); - Coef = transpose(matrix.metcoef(j)); + newID = getNewIndex(model.rxns); + j = find(strcmp(matrix.rxnIDs,newrxn.ID{i})); + Met = matrix.mets(j); + Coef = transpose(matrix.metcoef(j)); model = addReaction(model,... - ['r_' newID],... - 'reactionName', newrxn.ID{i},... - 'metaboliteList',Met,... - 'stoichCoeffList',Coef,... - 'reversible',newrxn.Rev(i,1),... - 'geneRule',newrxn.GPR{i},... - 'checkDuplicate',1); + ['r_' newID],... + 'reactionName', newrxn.ID{i},... + 'metaboliteList',Met,... + 'stoichCoeffList',Coef,... + 'reversible',newrxn.Rev(i,1),... + 'geneRule',newrxn.GPR{i},... + 'checkDuplicate',1); [EnergyResults,RedoxResults] = CheckEnergyProduction(model,{['r_' newID]},EnergyResults,RedoxResults); [MassChargeresults] = CheckBalanceforSce(model,{['r_' newID]},MassChargeresults); end -% add gene standard name for new genes +% Add gene standard name for new genes: fid = fopen('../../ComplementaryData/databases/SGDgeneNames.tsv'); yeast_gene_annotation = textscan(fid,'%s %s','Delimiter','\t','HeaderLines',1); fclose(fid); - geneIndex = zeros(1,1); for i = 1: length(model.genes) geneIndex = strcmp(yeast_gene_annotation{1}, model.genes{i}); @@ -148,24 +137,24 @@ end end -% Add protein name for genes +% Add protein name for genes: for i = 1:length(model.genes) model.proteins{i} = strcat('COBRAProtein',num2str(i)); end -%add rxn annotation +% Add rxn annotation: for i = 1:length(newrxn.ID) [~,rxnID] = ismember(newrxn.ID(i),model.rxnNames); if rxnID ~= 0 model.rxnNames{rxnID} = newrxn.rxnNames{i}; model.rxnECNumbers(rxnID) = newrxn.rxnECNumbers(i); - model.rxnKEGGID(rxnID) = newrxn.rxnKEGGID(i); + model.rxnKEGGID(rxnID) = newrxn.rxnKEGGID(i); end end % Save model: -model = rmfield(model,'grRules'); cd .. saveYeastModel(model) cd modelCuration +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% diff --git a/ModelFiles/dependencies.txt b/ModelFiles/dependencies.txt index c83ee6a1..43da025a 100644 --- a/ModelFiles/dependencies.txt +++ b/ModelFiles/dependencies.txt @@ -1,4 +1,4 @@ -MATLAB 9.1.0.441655 (R2016b) +MATLAB 9.4.0.813654 (R2018a) libSBML 5.17.0 RAVEN_toolbox 2.0.0 COBRA_toolbox commit ef3990e From bb93a169cb259beb3fb79335469478b478abff47 Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Mon, 27 Aug 2018 10:08:33 +0200 Subject: [PATCH 10/27] refactor: SubstrateUsage --- .../modelCuration/SubstrateUsage.m | 63 ++++++++----------- README.md | 2 +- 2 files changed, 26 insertions(+), 39 deletions(-) diff --git a/ComplementaryScripts/modelCuration/SubstrateUsage.m b/ComplementaryScripts/modelCuration/SubstrateUsage.m index 7d826a22..482319e6 100644 --- a/ComplementaryScripts/modelCuration/SubstrateUsage.m +++ b/ComplementaryScripts/modelCuration/SubstrateUsage.m @@ -69,59 +69,46 @@ end end - % Model prediction: + % Change media: newModel_test = newModel; - exchangeRxns = findExcRxns(newModel_test); + exchangeRxns = findExcRxns(newModel_test); newModel_test.lb(exchangeRxns) = 0; newModel_test.ub(exchangeRxns) = 1000; - desiredExchanges = {... - 'r_1992'; ... % 'oxygen exchange'; - 'r_1861'; ... % iron for test of expanded biomass def; - 'r_1832'; ... % hydrogen exchange; + commonExchanges = {... + 'r_1992'; ... % oxygen exchange + 'r_1861'; ... % iron exchange + 'r_1832'; ... % hydrogen exchange }; - glcExchange = {'r_1714'};% D-glucose exchange' - amoExchange = {'r_1654'}; % 'ammonium exchange' - phoExchange = {'r_2005'}; % 'phosphate exchange' - sulExchange = {'r_2060'}; % 'phosphate exchange' - uptakeRxnIndexes = findRxnIDs(newModel_test,desiredExchanges); + glcExchange = {'r_1714'}; % D-glucose exchange + amoExchange = {'r_1654'}; % ammonium exchange + phoExchange = {'r_2005'}; % phosphate exchange + sulExchange = {'r_2060'}; % phosphate exchange + SubRxnIndex = findRxnIDs(newModel_test,ExchRxn); + uptakeRxnIndexes = findRxnIDs(newModel_test,commonExchanges); amoExchangeIndex = findRxnIDs(newModel_test,amoExchange); phoExchangeIndex = findRxnIDs(newModel_test,phoExchange); glcExchangeIndex = findRxnIDs(newModel_test,glcExchange); sulExchangeIndex = findRxnIDs(newModel_test,sulExchange); - if length(uptakeRxnIndexes) ~= 3 %5; + if length(uptakeRxnIndexes) ~= 3 error('Not all exchange reactions were found.') end - newModel_test.lb(uptakeRxnIndexes)=-1000; - [~,ord] = ismember(metE,ExchRxn); + newModel_test.lb(uptakeRxnIndexes) = -1000; + newModel_test.lb(glcExchangeIndex) = -10; + newModel_test.lb(amoExchangeIndex) = -1000; + newModel_test.lb(phoExchangeIndex) = -1000; + newModel_test.lb(sulExchangeIndex) = -1000; if Subtype{i} == 'C' - newModel_test.lb(sulExchangeIndex)=-1000; - newModel_test.lb(amoExchangeIndex)=-1000; - newModel_test.lb(phoExchangeIndex)=-1000; - newModel_test.lb(glcExchangeIndex)=0; - SubRxnIndexes = findRxnIDs(newModel_test,ExchRxn); - newModel_test.lb(SubRxnIndexes)=-10; + newModel_test.lb(glcExchangeIndex) = 0; elseif Subtype{i} == 'N' - newModel_test.lb(sulExchangeIndex)=-1000; - newModel_test.lb(amoExchangeIndex)=0; - newModel_test.lb(phoExchangeIndex)=-1000; - newModel_test.lb(glcExchangeIndex)=-10; - SubRxnIndexes = findRxnIDs(newModel_test,ExchRxn); - newModel_test.lb(SubRxnIndexes)=-10; + newModel_test.lb(amoExchangeIndex) = 0; elseif Subtype{i} == 'P' - newModel_test.lb(sulExchangeIndex)=-1000; - newModel_test.lb(amoExchangeIndex)=-1000; - newModel_test.lb(phoExchangeIndex)=0; - newModel_test.lb(glcExchangeIndex)=-10; - SubRxnIndexes = findRxnIDs(newModel_test,ExchRxn); - newModel_test.lb(SubRxnIndexes)=-1000; + newModel_test.lb(phoExchangeIndex) = 0; elseif Subtype{i} == 'S' - newModel_test.lb(sulExchangeIndex)=0; - newModel_test.lb(amoExchangeIndex)=-1000; - newModel_test.lb(phoExchangeIndex)=-1000; - newModel_test.lb(glcExchangeIndex)=-10; - SubRxnIndexes = findRxnIDs(newModel_test,ExchRxn); - newModel_test.lb(SubRxnIndexes)=-1000; + newModel_test.lb(sulExchangeIndex) = 0; end + newModel_test.lb(SubRxnIndex) = -10; + + % Simulate model: sol = optimizeCbModel(newModel_test); if sol.obj > 0.000001 model = newModel; diff --git a/README.md b/README.md index 33d718fd..6b87d204 100644 --- a/README.md +++ b/README.md @@ -10,7 +10,7 @@ This repository contains the current consensus genome-scale metabolic model of _ **GEM Category:** Species; **Utilisation:** predictive simulation, multi-omics integrative analysis, _in silico_ strain design, model template; **Field:** metabolic-network reconstruction; **Type of Model:** curated, reconstruction; **Model Source:** [Yeast 7.6](https://sourceforge.net/projects/yeast/); **Taxonomy:** _Saccharomyces cerevisiae_; **Metabolic System:** General Metabolism; **Condition:** aerobic, glucose-limited, defined media, maximization of growth. -* Last update: 2018-08-26 +* Last update: 2018-08-27 * Main Model Descriptors: From fced36bd199224bbf9601bc24785bbf2b0f1c10a Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Mon, 27 Aug 2018 10:41:27 +0200 Subject: [PATCH 11/27] fix: confidence scores all exchange rxns should have a confidence score of NaN, and the other new reactions should have a confidence score of 1 (reactions without gene but needed for modelling) --- .../modelCuration/SubstrateUsage.m | 5 +- .../modelCuration/addBiologRxnToGEM.m | 7 +- ModelFiles/xml/yeastGEM.xml | 184 +++++++++--------- ModelFiles/yml/yeastGEM.yml | 113 ++--------- 4 files changed, 121 insertions(+), 188 deletions(-) diff --git a/ComplementaryScripts/modelCuration/SubstrateUsage.m b/ComplementaryScripts/modelCuration/SubstrateUsage.m index 482319e6..81c37288 100644 --- a/ComplementaryScripts/modelCuration/SubstrateUsage.m +++ b/ComplementaryScripts/modelCuration/SubstrateUsage.m @@ -69,6 +69,10 @@ end end + % Fix confidence score: + SubRxnIndex = findRxnIDs(newModel,ExchRxn); + newModel.rxnConfidenceScores(SubRxnIndex) = NaN; %exchange rxns + % Change media: newModel_test = newModel; exchangeRxns = findExcRxns(newModel_test); @@ -83,7 +87,6 @@ amoExchange = {'r_1654'}; % ammonium exchange phoExchange = {'r_2005'}; % phosphate exchange sulExchange = {'r_2060'}; % phosphate exchange - SubRxnIndex = findRxnIDs(newModel_test,ExchRxn); uptakeRxnIndexes = findRxnIDs(newModel_test,commonExchanges); amoExchangeIndex = findRxnIDs(newModel_test,amoExchange); phoExchangeIndex = findRxnIDs(newModel_test,phoExchange); diff --git a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m index d3172960..f5411a50 100644 --- a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m +++ b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m @@ -146,9 +146,10 @@ for i = 1:length(newrxn.ID) [~,rxnID] = ismember(newrxn.ID(i),model.rxnNames); if rxnID ~= 0 - model.rxnNames{rxnID} = newrxn.rxnNames{i}; - model.rxnECNumbers(rxnID) = newrxn.rxnECNumbers(i); - model.rxnKEGGID(rxnID) = newrxn.rxnKEGGID(i); + model.rxnNames{rxnID} = newrxn.rxnNames{i}; + model.rxnECNumbers(rxnID) = newrxn.rxnECNumbers(i); + model.rxnKEGGID(rxnID) = newrxn.rxnKEGGID(i); + model.rxnConfidenceScores(rxnID) = 1; %reactions without gene but needed for modelling end end diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index 876bddaf..97153de5 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -152938,7 +152938,7 @@ -

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Confidence Level: NaN

 @@ -183903,7 +183903,7 @@ -

Confidence Level: 0

+

Confidence Level: NaN

 @@ -183924,7 +183924,7 @@ -

Confidence Level: 0

+

Confidence Level: NaN

 @@ -183945,7 +183945,7 @@ -

Confidence Level: 0

+

Confidence Level: NaN

 @@ -183966,7 +183966,7 @@ -

Confidence Level: 0

+

Confidence Level: NaN

 @@ -183987,7 +183987,7 @@ -

Confidence Level: 0

+

Confidence Level: NaN

 @@ -184008,7 +184008,7 @@ -

Confidence Level: 0

+

Confidence Level: NaN

 @@ -184029,7 +184029,7 @@ -

Confidence Level: 0

+

Confidence Level: NaN

 @@ -184050,7 +184050,7 @@ -

Confidence Level: 0

+

Confidence Level: NaN

 @@ -184071,7 +184071,7 @@ -

Confidence Level: 0

+

Confidence Level: NaN

 @@ -184092,7 +184092,7 @@ -

Confidence Level: 0

+

Confidence Level: NaN

 diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index c105a4d7..e3abb90e 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -43995,7 +43995,6 @@ - s_1015: -1 - lower_bound: 0 - upper_bound: 1000 - - confidence_score: 0 - !!omap - id: r_1897 - name: L-isoleucine exchange @@ -79169,7 +79168,7 @@ - s_4067: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4347 - name: Guanosine 3'-phosphate phosphohydrolase @@ -79194,7 +79193,7 @@ - s_4069: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4349 - name: 2-Phosphoglycolate transport in/out via proton symport @@ -79241,7 +79240,7 @@ - s_4075: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4353 - name: Cysteamine:oxygen oxidoreductase @@ -79296,7 +79295,7 @@ - s_4080: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4357 - name: alkaline phosphatase @@ -79392,7 +79391,7 @@ - s_4090: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4365 - name: creatinine transport @@ -79403,7 +79402,7 @@ - s_4091: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4366 - name: ATP:L-arginine Nomega-phosphotransferase @@ -79878,7 +79877,7 @@ - s_4049: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4406 - name: D-O-Phosphoserine transport in/out via proton symport @@ -80251,7 +80250,7 @@ - s_4046: -1 - lower_bound: 0 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4437 - name: Gly-Glu transport via proton symport (excelluar to cytosol) @@ -80262,7 +80261,7 @@ - s_4060: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4438 - name: Gly-Glu transport via proton symport (cytosol to vacuole) @@ -80273,7 +80272,7 @@ - s_4061: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4439 - name: cytosol nonspecific dipeptidase @@ -80295,7 +80294,7 @@ - s_3758: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4441 - name: L-threonine transport, vacuoluar @@ -80304,7 +80303,7 @@ - s_4043: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4442 - name: Exchange reaction, cysteamine @@ -80312,7 +80311,7 @@ - s_4074: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4443 - name: 23cGMP transport via diffusion (extracellular to periplasm) @@ -80372,7 +80371,7 @@ - s_4144: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4449 - name: Met-Ala transport via proton symport (cytosol to vacuole) @@ -80383,7 +80382,7 @@ - s_4144: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4450 - name: O-Phospho-L-serine transport in via proton symport @@ -80574,7 +80573,7 @@ - s_4165: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4469 - name: L-Citrulline transport in via proton symport @@ -80605,7 +80604,7 @@ - s_4169: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4472 - name: Ala-Leu transport via proton symport (cytosol to vacuole) @@ -80616,7 +80615,7 @@ - s_4169: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4473 - name: L-alanylglycine transport via proton antiport @@ -80647,7 +80646,7 @@ - s_4173: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4476 - name: N-acetyl-L-glutamate transport @@ -80709,7 +80708,7 @@ - s_1467: 1 - lower_bound: 0 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4482 - name: L-alanine transport in via proton symport @@ -80845,7 +80844,7 @@ - s_4181: 1 - lower_bound: 0 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4492 - name: D-arabinitol:NAT 4-oxidoreductase @@ -80899,7 +80898,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4497 - name: Exchange reaction, 3-oxalomalate(3-) [extracellular] @@ -80908,7 +80906,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4498 - name: Exchange reaction, 6-O-alpha-D-glucopyranosyl-D-fructofuranose [extracellular] @@ -80917,7 +80914,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4499 - name: Exchange reaction, 5-dehydro-D-gluconate [extracellular] @@ -80926,7 +80922,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4500 - name: Exchange reaction, D-tagatose [extracellular] @@ -80935,7 +80930,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4501 - name: Exchange reaction, turanose [extracellular] @@ -80944,7 +80938,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4502 - name: Exchange reaction, D-glucose 6-phosphate [extracellular] @@ -80953,7 +80946,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4503 - name: Exchange reaction, alpha-maltotriose [extracellular] @@ -80962,7 +80954,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4504 - name: Exchange reaction, D-glucose 1-phosphate [extracellular] @@ -80971,7 +80962,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4505 - name: Exchange reaction, methyl alpha-D-glucopyranoside [extracellular] @@ -80980,7 +80970,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4506 - name: Exchange reaction, D-Glucosamine [extracellular] @@ -80989,7 +80978,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4507 - name: Exchange reaction, glycerone [extracellular] @@ -80998,7 +80986,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4508 - name: Exchange reaction, Ala-Gln [extracellular] @@ -81007,7 +80994,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4509 - name: Exchange reaction, Ala-Leu [extracellular] @@ -81016,7 +81002,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4510 - name: Exchange reaction, Gly-Gln [extracellular] @@ -81025,7 +81010,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4511 - name: Exchange reaction, Ala-His [extracellular] @@ -81034,7 +81018,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4512 - name: Exchange reaction, Gly-Asn [extracellular] @@ -81043,7 +81026,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4513 - name: Exchange reaction, Ala-Glu [extracellular] @@ -81052,7 +81034,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4514 - name: Exchange reaction, Gly-Met [extracellular] @@ -81061,7 +81042,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4515 - name: Exchange reaction, Ala-Asp [extracellular] @@ -81070,7 +81050,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4516 - name: Exchange reaction, Gly-Glu [extracellular] @@ -81079,7 +81058,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4517 - name: Exchange reaction, Ala-Thr [extracellular] @@ -81088,7 +81066,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4518 - name: Exchange reaction, Met-Ala [extracellular] @@ -81097,7 +81074,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4519 - name: Exchange reaction, L-citrulline [extracellular] @@ -81106,7 +81082,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4520 - name: Exchange reaction, 2-aminobutanoate [extracellular] @@ -81115,7 +81090,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4521 - name: Exchange reaction, choline phosphate [extracellular] @@ -81124,7 +81098,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4522 - name: Exchange reaction, glycerol 1-phosphate [extracellular] @@ -81133,7 +81106,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4523 - name: Exchange reaction, 2-phospho-D-glyceric acid [extracellular] @@ -81142,7 +81114,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4524 - name: Exchange reaction, GMP [extracellular] @@ -81151,7 +81122,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4525 - name: Exchange reaction, 3-phospho-serine [extracellular] @@ -81160,7 +81130,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4526 - name: Exchange reaction, O-phosphonatooxy-D-serine(2-) [extracellular] @@ -81169,7 +81138,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4527 - name: Exchange reaction, diphosphate [extracellular] @@ -81178,7 +81146,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4528 - name: Exchange reaction, triphosphate [extracellular] @@ -81187,7 +81154,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4529 - name: Exchange reaction, phosphoenolpyruvate [extracellular] @@ -81196,7 +81162,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4530 - name: Exchange reaction, N(omega)-phospho-L-arginine [extracellular] @@ -81205,7 +81170,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4531 - name: Exchange reaction, carbamoyl phosphate [extracellular] @@ -81214,7 +81178,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4532 - name: Exchange reaction, O-phosphoethanolamine [extracellular] @@ -81223,7 +81186,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4533 - name: Exchange reaction, cysteamine S-phosphate [extracellular] @@ -81232,7 +81194,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4534 - name: Exchange reaction, guanosine 2'-monophosphate [extracellular] @@ -81241,7 +81202,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4535 - name: Exchange reaction, glycerol 2-phosphate(2-) [extracellular] @@ -81250,7 +81210,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4536 - name: Exchange reaction, 3'-GMP [extracellular] @@ -81259,7 +81218,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4537 - name: Exchange reaction, 2-phosphoglycolate [extracellular] @@ -81268,7 +81226,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4538 - name: Exchange reaction, 6-phospho-D-gluconate [extracellular] @@ -81277,7 +81234,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4539 - name: Exchange reaction, D-mannose 6-phosphate [extracellular] @@ -81286,7 +81242,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4540 - name: Exchange reaction, 2',3'-cyclic GMP [extracellular] @@ -81295,7 +81250,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4541 - name: Exchange reaction, O(4)-phospho-L-tyrosine [extracellular] @@ -81304,7 +81258,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4542 - name: Exchange reaction, O-phospho-L-threonine [extracellular] @@ -81313,7 +81266,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4543 - name: Exchange reaction, 3-phosphonato-D-glycerate(3-) [extracellular] @@ -81322,7 +81274,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4544 - name: Exchange reaction, adenosine 2'-phosphate [extracellular] @@ -81331,7 +81282,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4545 - name: Exchange reaction, 3'-AMP [extracellular] @@ -81340,7 +81290,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4546 - name: Exchange reaction, 2',3'-cyclic AMP [extracellular] @@ -81349,7 +81298,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4547 - name: Exchange reaction, D-mannose 1-phosphate [extracellular] @@ -81358,7 +81306,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4548 - name: Exchange reaction, AMP [extracellular] @@ -81367,7 +81314,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4549 - name: Exchange reaction, N(alpha)-acetyl-L-methionine [extracellular] @@ -81376,7 +81322,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4550 - name: Exchange reaction, L-Methionine S-oxide [extracellular] @@ -81385,7 +81330,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4551 - name: Exchange reaction, 3-sulfino-L-alanine [extracellular] @@ -81394,7 +81338,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4552 - name: Exchange reaction, N-acetyl-L-cysteine [extracellular] @@ -81403,7 +81346,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4553 - name: Exchange reaction, L-cysteate [extracellular] @@ -81412,7 +81354,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4554 - name: Exchange reaction, 2-hydroxyethane-1-sulfonate [extracellular] @@ -81421,7 +81362,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4555 - name: Exchange reaction, acetoacetate [extracellular] @@ -81430,7 +81370,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4556 - name: Exchange reaction, N-acetyl-L-glutamate [extracellular] @@ -81439,7 +81378,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4557 - name: Exchange reaction, UMP [extracellular] @@ -81448,7 +81386,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4558 - name: Exchange reaction, CMP [extracellular] @@ -81457,7 +81394,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4559 - name: Exchange reaction, thymidine 5'-monophosphate [extracellular] @@ -81466,7 +81402,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4560 - name: Exchange reaction, thymidine 3'-monophosphate [extracellular] @@ -81475,7 +81410,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4561 - name: Exchange reaction, cytidine 2'-phosphate [extracellular] @@ -81484,7 +81418,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4562 - name: Exchange reaction, uridine 2'-phosphate [extracellular] @@ -81493,7 +81426,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4563 - name: Exchange reaction, 3'-UMP [extracellular] @@ -81502,7 +81434,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4564 - name: Exchange reaction, 2',3'-cyclic CMP [extracellular] @@ -81511,7 +81442,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - !!omap - id: r_4565 - name: Exchange reaction, 2',3'-cyclic UMP [extracellular] @@ -81520,7 +81450,6 @@ - lower_bound: 0 - upper_bound: 1000 - subsystem: Exchange - - confidence_score: 0 - genes: - !!omap - id: Q0045 From 389f846abb5abd054bd7abf4740af7dc5cd6b98b Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Mon, 27 Aug 2018 13:51:45 +0200 Subject: [PATCH 12/27] fix-rxn.annot: exchange rxnNames to comply with repo's standard: "met_name exchange" --- .../modelCuration/SubstrateUsage.m | 37 ++- ModelFiles/xml/yeastGEM.xml | 213 ++++++++++++------ ModelFiles/yml/yeastGEM.yml | 213 ++++++++++++------ 3 files changed, 292 insertions(+), 171 deletions(-) diff --git a/ComplementaryScripts/modelCuration/SubstrateUsage.m b/ComplementaryScripts/modelCuration/SubstrateUsage.m index 81c37288..9a3e9fa9 100644 --- a/ComplementaryScripts/modelCuration/SubstrateUsage.m +++ b/ComplementaryScripts/modelCuration/SubstrateUsage.m @@ -42,32 +42,27 @@ duplicateE = find(sum(newModel.S ~= 0, 1) == 1 & any(newModel.S == -1, 1) & any(newModel.S(metEOrd(metEOrd~=0), :), 1)); if ~isempty(duplicateE) warning(['Model already has the same exchange reaction you tried to add: ', newModel.rxns{duplicateE}]); - ExchRxn = newModel.rxns(duplicateE); + ExchRxn = newModel.rxns{duplicateE}; + ExchLB = newModel.lb(duplicateE); else if metEOrd == 0 - newID = getNewIndex(newModel.mets); - metE_temp_ID = strcat('s_',newID,'[e]'); - newModel = addMetabolite(newModel,metE_temp_ID, ... - 'metName',metE); - %adding exchange rxn for this metE - newID = getNewIndex(newModel.rxns); - [newModel,rxnIDexists] = addReaction(newModel,['r_' newID],... - 'reactionName',['Exchange reaction, ',metE],... - 'metaboliteList',cellstr(metE_temp_ID),'stoichCoeffList',-1,... - 'lowerBound',0, 'upperBound',1000, 'subSystem', 'Exchange', 'checkDuplicate', false); + newID = getNewIndex(newModel.mets); + metE_ID = strcat('s_',newID,'[e]'); + newModel = addMetabolite(newModel,metE_ID,'metName',metE); [~,metEOrd] = ismember(metE,newModel.metNames); - ExchRxn=['r_' newID]; - else - %adding exchange rxn for this metE - newID = getNewIndex(newModel.rxns); - [newModel,rxnIDexists] = addReaction(newModel,['r_' newID],... - 'reactionName',['Exchange reaction, ',metE],... - 'metaboliteList',newModel.mets(metEOrd),'stoichCoeffList',-1,... - 'lowerBound',0, 'upperBound',1000, 'subSystem', 'Exchange', 'checkDuplicate', false); - [~,metEOrd] = ismember(metE,newModel.metNames); - ExchRxn=['r_' newID]; end + %adding exchange rxn for this metE + newID = getNewIndex(newModel.rxns); + ExchRxn = ['r_' newID]; + ExchLB = 0; end + metE_ID = newModel.mets{metEOrd}; + [newModel,rxnIDexists] = addReaction(newModel,ExchRxn, ... + 'reactionName', [SubModelName{i}, ' exchange'], ... + 'metaboliteList', cellstr(metE_ID), 'stoichCoeffList', -1, ... + 'lowerBound', ExchLB, 'upperBound', 1000, 'subSystem', 'Exchange', ... + 'checkDuplicate', false); + newModel = rmfield(newModel,'grRules'); % Fix confidence score: SubRxnIndex = findRxnIDs(newModel,ExchRxn); diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index 97153de5..2d8a653a 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -147958,7 +147958,7 @@ - +

Confidence Level: NaN

@@ -148704,7 +148704,7 @@ - +

Confidence Level: NaN

@@ -150800,7 +150800,7 @@ - +

Confidence Level: NaN

@@ -151036,7 +151036,7 @@ - +

Confidence Level: NaN

@@ -152935,7 +152935,7 @@ - +

Confidence Level: NaN

@@ -182640,7 +182640,7 @@ - +

Confidence Level: NaN

@@ -182661,7 +182661,7 @@ - +

Confidence Level: NaN

@@ -182682,7 +182682,7 @@ - +

Confidence Level: NaN

@@ -182703,7 +182703,7 @@ - +

Confidence Level: NaN

@@ -182724,7 +182724,7 @@ - +

Confidence Level: NaN

@@ -182745,7 +182745,7 @@ - +

Confidence Level: NaN

@@ -182766,7 +182766,7 @@ - +

Confidence Level: NaN

@@ -182787,7 +182787,7 @@ - +

Confidence Level: NaN

@@ -182808,7 +182808,7 @@ - +

Confidence Level: NaN

@@ -182829,7 +182829,7 @@ - +

Confidence Level: NaN

@@ -182850,7 +182850,7 @@ - +

Confidence Level: NaN

@@ -182871,7 +182871,7 @@ - +

Confidence Level: NaN

@@ -182892,7 +182892,7 @@ - +

Confidence Level: NaN

@@ -182913,7 +182913,7 @@ - +

Confidence Level: NaN

@@ -182934,7 +182934,7 @@ - +

Confidence Level: NaN

@@ -182955,7 +182955,7 @@ - +

Confidence Level: NaN

@@ -182976,7 +182976,7 @@ - +

Confidence Level: NaN

@@ -182997,7 +182997,7 @@ - +

Confidence Level: NaN

@@ -183018,7 +183018,7 @@ - +

Confidence Level: NaN

@@ -183039,7 +183039,7 @@ - +

Confidence Level: NaN

@@ -183060,7 +183060,7 @@ - +

Confidence Level: NaN

@@ -183081,7 +183081,7 @@ - +

Confidence Level: NaN

@@ -183102,7 +183102,7 @@ - +

Confidence Level: NaN

@@ -183123,7 +183123,7 @@ - +

Confidence Level: NaN

@@ -183144,7 +183144,7 @@ - +

Confidence Level: NaN

@@ -183165,7 +183165,7 @@ - +

Confidence Level: NaN

@@ -183186,7 +183186,7 @@ - +

Confidence Level: NaN

@@ -183207,7 +183207,7 @@ - +

Confidence Level: NaN

@@ -183228,7 +183228,7 @@ - +

Confidence Level: NaN

@@ -183249,7 +183249,7 @@ - +

Confidence Level: NaN

@@ -183270,7 +183270,7 @@ - +

Confidence Level: NaN

@@ -183291,7 +183291,7 @@ - +

Confidence Level: NaN

@@ -183312,7 +183312,7 @@ - +

Confidence Level: NaN

@@ -183333,7 +183333,7 @@ - +

Confidence Level: NaN

@@ -183354,7 +183354,7 @@ - +

Confidence Level: NaN

@@ -183375,7 +183375,7 @@ - +

Confidence Level: NaN

@@ -183396,7 +183396,7 @@ - +

Confidence Level: NaN

@@ -183417,7 +183417,7 @@ - +

Confidence Level: NaN

@@ -183438,7 +183438,7 @@ - +

Confidence Level: NaN

@@ -183459,7 +183459,7 @@ - +

Confidence Level: NaN

@@ -183480,7 +183480,7 @@ - +

Confidence Level: NaN

@@ -183501,7 +183501,7 @@ - +

Confidence Level: NaN

@@ -183522,7 +183522,7 @@ - +

Confidence Level: NaN

@@ -183543,7 +183543,7 @@ - +

Confidence Level: NaN

@@ -183564,7 +183564,7 @@ - +

Confidence Level: NaN

@@ -183585,7 +183585,7 @@ - +

Confidence Level: NaN

@@ -183606,7 +183606,7 @@ - +

Confidence Level: NaN

@@ -183627,7 +183627,7 @@ - +

Confidence Level: NaN

@@ -183648,7 +183648,7 @@ - +

Confidence Level: NaN

@@ -183669,7 +183669,7 @@ - +

Confidence Level: NaN

@@ -183690,7 +183690,7 @@ - +

Confidence Level: NaN

@@ -183711,7 +183711,7 @@ - +

Confidence Level: NaN

@@ -183732,7 +183732,7 @@ - +

Confidence Level: NaN

@@ -183753,7 +183753,7 @@ - +

Confidence Level: NaN

@@ -183774,7 +183774,7 @@ - +

Confidence Level: NaN

@@ -183795,7 +183795,7 @@ - +

Confidence Level: NaN

@@ -183816,7 +183816,7 @@ - +

Confidence Level: NaN

@@ -183837,7 +183837,7 @@ - +

Confidence Level: NaN

@@ -183858,7 +183858,7 @@ - +

Confidence Level: NaN

@@ -183879,7 +183879,7 @@ - +

Confidence Level: NaN

@@ -183900,7 +183900,7 @@ - +

Confidence Level: NaN

@@ -183921,7 +183921,7 @@ - +

Confidence Level: NaN

@@ -183942,7 +183942,7 @@ - +

Confidence Level: NaN

@@ -183963,7 +183963,7 @@ - +

Confidence Level: NaN

@@ -183984,7 +183984,7 @@ - +

Confidence Level: NaN

@@ -184005,7 +184005,7 @@ - +

Confidence Level: NaN

@@ -184026,7 +184026,7 @@ - +

Confidence Level: NaN

@@ -184047,7 +184047,7 @@ - +

Confidence Level: NaN

@@ -184068,7 +184068,7 @@ - +

Confidence Level: NaN

@@ -184089,7 +184089,7 @@ - +

Confidence Level: NaN

@@ -185256,6 +185256,69 @@ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index e3abb90e..730e567c 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -41398,6 +41398,7 @@ - s_0064: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1552 - name: (S)-malate exchange @@ -41405,6 +41406,7 @@ - s_0067: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1553 - name: 1-(sn-glycero-3-phospho)-1D-myo-inositol exchange @@ -41599,6 +41601,7 @@ - s_0181: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1587 - name: 2-oxoglutarate transport @@ -41990,6 +41993,7 @@ - s_0364: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1635 - name: acetate transport @@ -42024,6 +42028,7 @@ - s_0384: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1640 - name: adenine transport @@ -42056,6 +42061,7 @@ - s_0387: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1644 - name: ADP transport @@ -42097,13 +42103,15 @@ - s_0408: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1650 - - name: alpha,alpha-trehalose exchange + - name: trehalose exchange - metabolites: !!omap - s_1521: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1651 - name: alpha-D-glucosamine 6-phosphate exchange @@ -42111,6 +42119,7 @@ - s_0413: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1652 - name: alpha-ketoglutarate/malate transporter @@ -42129,6 +42138,7 @@ - s_0420: -1 - lower_bound: -1000 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1656 - name: AMP transport @@ -42398,11 +42408,12 @@ - confidence_score: 0 - !!omap - id: r_1687 - - name: citrate(3-) exchange + - name: citrate exchange - metabolites: !!omap - s_0523: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1688 - name: citrate/isocitrate antiport @@ -42515,6 +42526,7 @@ - s_0544: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1703 - name: cytidylate kinase (CMP) @@ -42544,6 +42556,7 @@ - s_0546: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1706 - name: D-arabinose exchange @@ -42551,6 +42564,7 @@ - s_0549: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1707 - name: D-arabinose transport @@ -42576,6 +42590,7 @@ - s_0554: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1710 - name: D-galactose exchange @@ -42583,6 +42598,7 @@ - s_0559: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1711 - name: D-galacturonate exchange @@ -42597,6 +42613,7 @@ - s_0562: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1713 - name: D-glucosamine 6-phosphate uniport @@ -42613,6 +42630,7 @@ - s_0565: -1 - lower_bound: -1 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1715 - name: D-mannose exchange @@ -42620,6 +42638,7 @@ - s_0572: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1716 - name: D-ribose exchange @@ -42627,6 +42646,7 @@ - s_0576: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1717 - name: D-sorbitol transport @@ -42643,6 +42663,7 @@ - s_0579: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1719 - name: D-xylose transport @@ -42734,6 +42755,7 @@ - s_0597: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1728 - name: deoxyadenosine transport @@ -43003,6 +43025,7 @@ - s_0681: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1762 - name: ethanol transport @@ -43148,6 +43171,7 @@ - s_0723: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1794 - name: formate transport @@ -43189,11 +43213,12 @@ - confidence_score: 0 - !!omap - id: r_1798 - - name: fumarate(2-) exchange + - name: fumarate exchange - metabolites: !!omap - s_0726: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1800 - name: gamma-aminobutyrate exchange @@ -43201,6 +43226,7 @@ - s_0736: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1801 - name: GDP transport @@ -43252,6 +43278,7 @@ - s_0751: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1808 - name: glycerol exchange @@ -43259,6 +43286,7 @@ - s_0766: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1809 - name: glycerol-3-phosphate shuttle @@ -43272,11 +43300,12 @@ - confidence_score: 0 - !!omap - id: r_1810 - - name: glycine exchange + - name: L-glycine exchange - metabolites: !!omap - s_1004: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1811 - name: glycine transport @@ -43318,6 +43347,7 @@ - s_0780: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1816 - name: glyoxylate transport @@ -43343,6 +43373,7 @@ - s_0788: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1819 - name: guanine transport @@ -43359,6 +43390,7 @@ - s_0791: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1821 - name: guanosine kinase @@ -43599,6 +43631,7 @@ - s_0857: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1848 - name: inosine transport @@ -43826,6 +43859,7 @@ - s_0956: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1874 - name: L-alanine transport @@ -43842,6 +43876,7 @@ - s_0962: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1876 - name: L-arabinitol transport @@ -43867,6 +43902,7 @@ - s_0964: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1879 - name: L-arginine exchange @@ -43874,6 +43910,7 @@ - s_0966: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1880 - name: L-asparagine exchange @@ -43881,6 +43918,7 @@ - s_0970: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1881 - name: L-aspartate exchange @@ -43888,6 +43926,7 @@ - s_0974: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1882 - name: L-carnitine transport @@ -43904,6 +43943,7 @@ - s_0982: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1884 - name: L-erythro-4-hydroxyglutamate transport @@ -43947,6 +43987,7 @@ - s_0992: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1890 - name: L-glutamate transport @@ -43963,6 +44004,7 @@ - s_1000: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1892 - name: L-glutamine transport @@ -43990,11 +44032,12 @@ - confidence_score: 0 - !!omap - id: r_1896 - - name: L-homoserine transport + - name: L-homoserine exchange - metabolites: !!omap - s_1015: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1897 - name: L-isoleucine exchange @@ -44002,6 +44045,7 @@ - s_1017: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1898 - name: L-isoleucine transport @@ -44018,6 +44062,7 @@ - s_1022: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1900 - name: L-lysine exchange @@ -44041,6 +44086,7 @@ - s_1030: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1903 - name: L-phenylalanine exchange @@ -44048,6 +44094,7 @@ - s_1033: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1904 - name: L-proline exchange @@ -44055,6 +44102,7 @@ - s_1036: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1905 - name: L-proline transport @@ -44071,6 +44119,7 @@ - s_1041: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1907 - name: L-serine transport @@ -44112,6 +44161,7 @@ - s_1046: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1912 - name: L-tryptophan exchange @@ -44119,6 +44169,7 @@ - s_1049: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1913 - name: L-tyrosine exchange @@ -44126,6 +44177,7 @@ - s_1052: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1914 - name: L-valine exchange @@ -44133,6 +44185,7 @@ - s_1057: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1915 - name: lanosterol exchange @@ -44264,6 +44317,7 @@ - s_1106: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1932 - name: mannan transport @@ -44565,6 +44619,7 @@ - s_1267: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_1988 - name: oxaloacetate transport @@ -44714,6 +44769,7 @@ - s_1324: -1 - lower_bound: -1000 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_2008 - name: phosphate transport @@ -44852,6 +44908,7 @@ - s_1400: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_2034 - name: pyruvate transport @@ -45022,6 +45079,7 @@ - s_1459: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_2057 - name: succinate transport @@ -45038,6 +45096,7 @@ - s_1466: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_2060 - name: sulphate exchange @@ -45045,6 +45104,7 @@ - s_1468: -1 - lower_bound: -1000 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_2061 - name: sulphite exchange @@ -45297,6 +45357,7 @@ - s_1553: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_2092 - name: uridine exchange @@ -45406,6 +45467,7 @@ - s_1567: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_2105 - name: xylitol transport @@ -75039,6 +75101,7 @@ - s_3715: -1 - lower_bound: 0 - upper_bound: 1000 + - subsystem: Exchange - !!omap - id: r_4044 - name: melibiose exchange @@ -80892,7 +80955,7 @@ - confidence_score: 0 - !!omap - id: r_4496 - - name: Exchange reaction, Ala-Gly [extracellular] + - name: Ala-Gly exchange - metabolites: !!omap - s_4170: -1 - lower_bound: 0 @@ -80900,7 +80963,7 @@ - subsystem: Exchange - !!omap - id: r_4497 - - name: Exchange reaction, 3-oxalomalate(3-) [extracellular] + - name: 3-oxalomalate(3-) exchange - metabolites: !!omap - s_4137: -1 - lower_bound: 0 @@ -80908,7 +80971,7 @@ - subsystem: Exchange - !!omap - id: r_4498 - - name: Exchange reaction, 6-O-alpha-D-glucopyranosyl-D-fructofuranose [extracellular] + - name: 6-O-alpha-D-glucopyranosyl-D-fructofuranose exchange - metabolites: !!omap - s_4109: -1 - lower_bound: 0 @@ -80916,7 +80979,7 @@ - subsystem: Exchange - !!omap - id: r_4499 - - name: Exchange reaction, 5-dehydro-D-gluconate [extracellular] + - name: 5-dehydro-D-gluconate exchange - metabolites: !!omap - s_4118: -1 - lower_bound: 0 @@ -80924,7 +80987,7 @@ - subsystem: Exchange - !!omap - id: r_4500 - - name: Exchange reaction, D-tagatose [extracellular] + - name: D-tagatose exchange - metabolites: !!omap - s_4130: -1 - lower_bound: 0 @@ -80932,7 +80995,7 @@ - subsystem: Exchange - !!omap - id: r_4501 - - name: Exchange reaction, turanose [extracellular] + - name: turanose exchange - metabolites: !!omap - s_4131: -1 - lower_bound: 0 @@ -80940,7 +81003,7 @@ - subsystem: Exchange - !!omap - id: r_4502 - - name: Exchange reaction, D-glucose 6-phosphate [extracellular] + - name: D-glucose 6-phosphate exchange - metabolites: !!omap - s_4150: -1 - lower_bound: 0 @@ -80948,7 +81011,7 @@ - subsystem: Exchange - !!omap - id: r_4503 - - name: Exchange reaction, alpha-maltotriose [extracellular] + - name: alpha-maltotriose exchange - metabolites: !!omap - s_4140: -1 - lower_bound: 0 @@ -80956,7 +81019,7 @@ - subsystem: Exchange - !!omap - id: r_4504 - - name: Exchange reaction, D-glucose 1-phosphate [extracellular] + - name: D-glucose 1-phosphate exchange - metabolites: !!omap - s_4145: -1 - lower_bound: 0 @@ -80964,7 +81027,7 @@ - subsystem: Exchange - !!omap - id: r_4505 - - name: Exchange reaction, methyl alpha-D-glucopyranoside [extracellular] + - name: methyl alpha-D-glucopyranoside exchange - metabolites: !!omap - s_4125: -1 - lower_bound: 0 @@ -80972,7 +81035,7 @@ - subsystem: Exchange - !!omap - id: r_4506 - - name: Exchange reaction, D-Glucosamine [extracellular] + - name: D-Glucosamine exchange - metabolites: !!omap - s_4164: -1 - lower_bound: 0 @@ -80980,7 +81043,7 @@ - subsystem: Exchange - !!omap - id: r_4507 - - name: Exchange reaction, glycerone [extracellular] + - name: glycerone exchange - metabolites: !!omap - s_4167: -1 - lower_bound: 0 @@ -80988,7 +81051,7 @@ - subsystem: Exchange - !!omap - id: r_4508 - - name: Exchange reaction, Ala-Gln [extracellular] + - name: Ala-Gln exchange - metabolites: !!omap - s_4034: -1 - lower_bound: 0 @@ -80996,7 +81059,7 @@ - subsystem: Exchange - !!omap - id: r_4509 - - name: Exchange reaction, Ala-Leu [extracellular] + - name: Ala-Leu exchange - metabolites: !!omap - s_4168: -1 - lower_bound: 0 @@ -81004,7 +81067,7 @@ - subsystem: Exchange - !!omap - id: r_4510 - - name: Exchange reaction, Gly-Gln [extracellular] + - name: Gly-Gln exchange - metabolites: !!omap - s_4056: -1 - lower_bound: 0 @@ -81012,7 +81075,7 @@ - subsystem: Exchange - !!omap - id: r_4511 - - name: Exchange reaction, Ala-His [extracellular] + - name: Ala-His exchange - metabolites: !!omap - s_4050: -1 - lower_bound: 0 @@ -81020,7 +81083,7 @@ - subsystem: Exchange - !!omap - id: r_4512 - - name: Exchange reaction, Gly-Asn [extracellular] + - name: Gly-Asn exchange - metabolites: !!omap - s_4053: -1 - lower_bound: 0 @@ -81028,7 +81091,7 @@ - subsystem: Exchange - !!omap - id: r_4513 - - name: Exchange reaction, Ala-Glu [extracellular] + - name: Ala-Glu exchange - metabolites: !!omap - s_4037: -1 - lower_bound: 0 @@ -81036,7 +81099,7 @@ - subsystem: Exchange - !!omap - id: r_4514 - - name: Exchange reaction, Gly-Met [extracellular] + - name: Gly-Met exchange - metabolites: !!omap - s_4085: -1 - lower_bound: 0 @@ -81044,7 +81107,7 @@ - subsystem: Exchange - !!omap - id: r_4515 - - name: Exchange reaction, Ala-Asp [extracellular] + - name: Ala-Asp exchange - metabolites: !!omap - s_4119: -1 - lower_bound: 0 @@ -81052,7 +81115,7 @@ - subsystem: Exchange - !!omap - id: r_4516 - - name: Exchange reaction, Gly-Glu [extracellular] + - name: Gly-Glu exchange - metabolites: !!omap - s_4059: -1 - lower_bound: 0 @@ -81060,7 +81123,7 @@ - subsystem: Exchange - !!omap - id: r_4517 - - name: Exchange reaction, Ala-Thr [extracellular] + - name: Ala-Thr exchange - metabolites: !!omap - s_4040: -1 - lower_bound: 0 @@ -81068,7 +81131,7 @@ - subsystem: Exchange - !!omap - id: r_4518 - - name: Exchange reaction, Met-Ala [extracellular] + - name: Met-Ala exchange - metabolites: !!omap - s_4143: -1 - lower_bound: 0 @@ -81076,7 +81139,7 @@ - subsystem: Exchange - !!omap - id: r_4519 - - name: Exchange reaction, L-citrulline [extracellular] + - name: L-citrulline exchange - metabolites: !!omap - s_4166: -1 - lower_bound: 0 @@ -81084,7 +81147,7 @@ - subsystem: Exchange - !!omap - id: r_4520 - - name: Exchange reaction, 2-aminobutanoate [extracellular] + - name: 2-aminobutanoate exchange - metabolites: !!omap - s_4080: -1 - lower_bound: 0 @@ -81092,7 +81155,7 @@ - subsystem: Exchange - !!omap - id: r_4521 - - name: Exchange reaction, choline phosphate [extracellular] + - name: choline phosphate exchange - metabolites: !!omap - s_4158: -1 - lower_bound: 0 @@ -81100,7 +81163,7 @@ - subsystem: Exchange - !!omap - id: r_4522 - - name: Exchange reaction, glycerol 1-phosphate [extracellular] + - name: glycerol 1-phosphate exchange - metabolites: !!omap - s_4049: -1 - lower_bound: 0 @@ -81108,7 +81171,7 @@ - subsystem: Exchange - !!omap - id: r_4523 - - name: Exchange reaction, 2-phospho-D-glyceric acid [extracellular] + - name: 2-phospho-D-glyceric acid exchange - metabolites: !!omap - s_4141: -1 - lower_bound: 0 @@ -81116,7 +81179,7 @@ - subsystem: Exchange - !!omap - id: r_4524 - - name: Exchange reaction, GMP [extracellular] + - name: GMP exchange - metabolites: !!omap - s_4148: -1 - lower_bound: 0 @@ -81124,7 +81187,7 @@ - subsystem: Exchange - !!omap - id: r_4525 - - name: Exchange reaction, 3-phospho-serine [extracellular] + - name: 3-phospho-serine exchange - metabolites: !!omap - s_4147: -1 - lower_bound: 0 @@ -81132,7 +81195,7 @@ - subsystem: Exchange - !!omap - id: r_4526 - - name: Exchange reaction, O-phosphonatooxy-D-serine(2-) [extracellular] + - name: O-phosphonatooxy-D-serine(2-) exchange - metabolites: !!omap - s_4078: -1 - lower_bound: 0 @@ -81140,7 +81203,7 @@ - subsystem: Exchange - !!omap - id: r_4527 - - name: Exchange reaction, diphosphate [extracellular] + - name: diphosphate exchange - metabolites: !!omap - s_4157: -1 - lower_bound: 0 @@ -81148,7 +81211,7 @@ - subsystem: Exchange - !!omap - id: r_4528 - - name: Exchange reaction, triphosphate [extracellular] + - name: triphosphate exchange - metabolites: !!omap - s_4099: -1 - lower_bound: 0 @@ -81156,7 +81219,7 @@ - subsystem: Exchange - !!omap - id: r_4529 - - name: Exchange reaction, phosphoenolpyruvate [extracellular] + - name: phosphoenolpyruvate exchange - metabolites: !!omap - s_4152: -1 - lower_bound: 0 @@ -81164,7 +81227,7 @@ - subsystem: Exchange - !!omap - id: r_4530 - - name: Exchange reaction, N(omega)-phospho-L-arginine [extracellular] + - name: N(omega)-phospho-L-arginine exchange - metabolites: !!omap - s_4093: -1 - lower_bound: 0 @@ -81172,7 +81235,7 @@ - subsystem: Exchange - !!omap - id: r_4531 - - name: Exchange reaction, carbamoyl phosphate [extracellular] + - name: carbamoyl phosphate exchange - metabolites: !!omap - s_4146: -1 - lower_bound: 0 @@ -81180,7 +81243,7 @@ - subsystem: Exchange - !!omap - id: r_4532 - - name: Exchange reaction, O-phosphoethanolamine [extracellular] + - name: O-phosphoethanolamine exchange - metabolites: !!omap - s_4154: -1 - lower_bound: 0 @@ -81188,7 +81251,7 @@ - subsystem: Exchange - !!omap - id: r_4533 - - name: Exchange reaction, cysteamine S-phosphate [extracellular] + - name: cysteamine S-phosphate exchange - metabolites: !!omap - s_4075: -1 - lower_bound: 0 @@ -81196,7 +81259,7 @@ - subsystem: Exchange - !!omap - id: r_4534 - - name: Exchange reaction, guanosine 2'-monophosphate [extracellular] + - name: guanosine 2'-monophosphate exchange - metabolites: !!omap - s_4067: -1 - lower_bound: 0 @@ -81204,7 +81267,7 @@ - subsystem: Exchange - !!omap - id: r_4535 - - name: Exchange reaction, glycerol 2-phosphate(2-) [extracellular] + - name: glycerol 2-phosphate(2-) exchange - metabolites: !!omap - s_4063: -1 - lower_bound: 0 @@ -81212,7 +81275,7 @@ - subsystem: Exchange - !!omap - id: r_4536 - - name: Exchange reaction, 3'-GMP [extracellular] + - name: 3'-GMP exchange - metabolites: !!omap - s_4069: -1 - lower_bound: 0 @@ -81220,7 +81283,7 @@ - subsystem: Exchange - !!omap - id: r_4537 - - name: Exchange reaction, 2-phosphoglycolate [extracellular] + - name: 2-phosphoglycolate exchange - metabolites: !!omap - s_4070: -1 - lower_bound: 0 @@ -81228,7 +81291,7 @@ - subsystem: Exchange - !!omap - id: r_4538 - - name: Exchange reaction, 6-phospho-D-gluconate [extracellular] + - name: 6-phospho-D-gluconate exchange - metabolites: !!omap - s_4155: -1 - lower_bound: 0 @@ -81236,7 +81299,7 @@ - subsystem: Exchange - !!omap - id: r_4539 - - name: Exchange reaction, D-mannose 6-phosphate [extracellular] + - name: D-mannose 6-phosphate exchange - metabolites: !!omap - s_4153: -1 - lower_bound: 0 @@ -81244,7 +81307,7 @@ - subsystem: Exchange - !!omap - id: r_4540 - - name: Exchange reaction, 2',3'-cyclic GMP [extracellular] + - name: 2',3'-cyclic GMP exchange - metabolites: !!omap - s_4095: -1 - lower_bound: 0 @@ -81252,7 +81315,7 @@ - subsystem: Exchange - !!omap - id: r_4541 - - name: Exchange reaction, O(4)-phospho-L-tyrosine [extracellular] + - name: O(4)-phospho-L-tyrosine exchange - metabolites: !!omap - s_4097: -1 - lower_bound: 0 @@ -81260,7 +81323,7 @@ - subsystem: Exchange - !!omap - id: r_4542 - - name: Exchange reaction, O-phospho-L-threonine [extracellular] + - name: O-phospho-L-threonine exchange - metabolites: !!omap - s_4065: -1 - lower_bound: 0 @@ -81268,7 +81331,7 @@ - subsystem: Exchange - !!omap - id: r_4543 - - name: Exchange reaction, 3-phosphonato-D-glycerate(3-) [extracellular] + - name: 3-phosphonato-D-glycerate(3-) exchange - metabolites: !!omap - s_4142: -1 - lower_bound: 0 @@ -81276,7 +81339,7 @@ - subsystem: Exchange - !!omap - id: r_4544 - - name: Exchange reaction, adenosine 2'-phosphate [extracellular] + - name: adenosine 2'-phosphate exchange - metabolites: !!omap - s_4162: -1 - lower_bound: 0 @@ -81284,7 +81347,7 @@ - subsystem: Exchange - !!omap - id: r_4545 - - name: Exchange reaction, 3'-AMP [extracellular] + - name: 3'-AMP exchange - metabolites: !!omap - s_4107: -1 - lower_bound: 0 @@ -81292,7 +81355,7 @@ - subsystem: Exchange - !!omap - id: r_4546 - - name: Exchange reaction, 2',3'-cyclic AMP [extracellular] + - name: 2',3'-cyclic AMP exchange - metabolites: !!omap - s_4161: -1 - lower_bound: 0 @@ -81300,7 +81363,7 @@ - subsystem: Exchange - !!omap - id: r_4547 - - name: Exchange reaction, D-mannose 1-phosphate [extracellular] + - name: D-mannose 1-phosphate exchange - metabolites: !!omap - s_4156: -1 - lower_bound: 0 @@ -81308,7 +81371,7 @@ - subsystem: Exchange - !!omap - id: r_4548 - - name: Exchange reaction, AMP [extracellular] + - name: AMP exchange - metabolites: !!omap - s_4160: -1 - lower_bound: 0 @@ -81316,7 +81379,7 @@ - subsystem: Exchange - !!omap - id: r_4549 - - name: Exchange reaction, N(alpha)-acetyl-L-methionine [extracellular] + - name: N(alpha)-acetyl-L-methionine exchange - metabolites: !!omap - s_4135: -1 - lower_bound: 0 @@ -81324,7 +81387,7 @@ - subsystem: Exchange - !!omap - id: r_4550 - - name: Exchange reaction, L-Methionine S-oxide [extracellular] + - name: L-Methionine S-oxide exchange - metabolites: !!omap - s_4176: -1 - lower_bound: 0 @@ -81332,7 +81395,7 @@ - subsystem: Exchange - !!omap - id: r_4551 - - name: Exchange reaction, 3-sulfino-L-alanine [extracellular] + - name: 3-sulfino-L-alanine exchange - metabolites: !!omap - s_4105: -1 - lower_bound: 0 @@ -81340,7 +81403,7 @@ - subsystem: Exchange - !!omap - id: r_4552 - - name: Exchange reaction, N-acetyl-L-cysteine [extracellular] + - name: N-acetyl-L-cysteine exchange - metabolites: !!omap - s_4111: -1 - lower_bound: 0 @@ -81348,7 +81411,7 @@ - subsystem: Exchange - !!omap - id: r_4553 - - name: Exchange reaction, L-cysteate [extracellular] + - name: L-cysteate exchange - metabolites: !!omap - s_4139: -1 - lower_bound: 0 @@ -81356,7 +81419,7 @@ - subsystem: Exchange - !!omap - id: r_4554 - - name: Exchange reaction, 2-hydroxyethane-1-sulfonate [extracellular] + - name: 2-hydroxyethane-1-sulfonate exchange - metabolites: !!omap - s_4116: -1 - lower_bound: 0 @@ -81364,7 +81427,7 @@ - subsystem: Exchange - !!omap - id: r_4555 - - name: Exchange reaction, acetoacetate [extracellular] + - name: acetoacetate exchange - metabolites: !!omap - s_4133: -1 - lower_bound: 0 @@ -81372,7 +81435,7 @@ - subsystem: Exchange - !!omap - id: r_4556 - - name: Exchange reaction, N-acetyl-L-glutamate [extracellular] + - name: N-acetyl-L-glutamate exchange - metabolites: !!omap - s_4172: -1 - lower_bound: 0 @@ -81380,7 +81443,7 @@ - subsystem: Exchange - !!omap - id: r_4557 - - name: Exchange reaction, UMP [extracellular] + - name: UMP exchange - metabolites: !!omap - s_4151: -1 - lower_bound: 0 @@ -81388,7 +81451,7 @@ - subsystem: Exchange - !!omap - id: r_4558 - - name: Exchange reaction, CMP [extracellular] + - name: CMP exchange - metabolites: !!omap - s_4163: -1 - lower_bound: 0 @@ -81396,7 +81459,7 @@ - subsystem: Exchange - !!omap - id: r_4559 - - name: Exchange reaction, thymidine 5'-monophosphate [extracellular] + - name: thymidine 5'-monophosphate exchange - metabolites: !!omap - s_4047: -1 - lower_bound: 0 @@ -81404,7 +81467,7 @@ - subsystem: Exchange - !!omap - id: r_4560 - - name: Exchange reaction, thymidine 3'-monophosphate [extracellular] + - name: thymidine 3'-monophosphate exchange - metabolites: !!omap - s_4045: -1 - lower_bound: 0 @@ -81412,7 +81475,7 @@ - subsystem: Exchange - !!omap - id: r_4561 - - name: Exchange reaction, cytidine 2'-phosphate [extracellular] + - name: cytidine 2'-phosphate exchange - metabolites: !!omap - s_4101: -1 - lower_bound: 0 @@ -81420,7 +81483,7 @@ - subsystem: Exchange - !!omap - id: r_4562 - - name: Exchange reaction, uridine 2'-phosphate [extracellular] + - name: uridine 2'-phosphate exchange - metabolites: !!omap - s_4082: -1 - lower_bound: 0 @@ -81428,7 +81491,7 @@ - subsystem: Exchange - !!omap - id: r_4563 - - name: Exchange reaction, 3'-UMP [extracellular] + - name: 3'-UMP exchange - metabolites: !!omap - s_4084: -1 - lower_bound: 0 @@ -81436,7 +81499,7 @@ - subsystem: Exchange - !!omap - id: r_4564 - - name: Exchange reaction, 2',3'-cyclic CMP [extracellular] + - name: 2',3'-cyclic CMP exchange - metabolites: !!omap - s_4127: -1 - lower_bound: 0 @@ -81444,7 +81507,7 @@ - subsystem: Exchange - !!omap - id: r_4565 - - name: Exchange reaction, 2',3'-cyclic UMP [extracellular] + - name: 2',3'-cyclic UMP exchange - metabolites: !!omap - s_4103: -1 - lower_bound: 0 From bfec0a5037e6b847763ed216cd247fd6dea3aa83 Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Mon, 27 Aug 2018 14:04:57 +0200 Subject: [PATCH 13/27] fix-rxn.annot: exchange subSystems removed "Exchange" as subSystem (currently not compliant with repo) --- .../modelCuration/SubstrateUsage.m | 2 +- ModelFiles/xml/yeastGEM.xml | 317 +++++------------- ModelFiles/yml/yeastGEM.yml | 133 -------- 3 files changed, 91 insertions(+), 361 deletions(-) diff --git a/ComplementaryScripts/modelCuration/SubstrateUsage.m b/ComplementaryScripts/modelCuration/SubstrateUsage.m index 9a3e9fa9..f373a820 100644 --- a/ComplementaryScripts/modelCuration/SubstrateUsage.m +++ b/ComplementaryScripts/modelCuration/SubstrateUsage.m @@ -60,7 +60,7 @@ [newModel,rxnIDexists] = addReaction(newModel,ExchRxn, ... 'reactionName', [SubModelName{i}, ' exchange'], ... 'metaboliteList', cellstr(metE_ID), 'stoichCoeffList', -1, ... - 'lowerBound', ExchLB, 'upperBound', 1000, 'subSystem', 'Exchange', ... + 'lowerBound', ExchLB, 'upperBound', 1000, 'subSystem', '', ... 'checkDuplicate', false); newModel = rmfield(newModel,'grRules'); diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index 2d8a653a..2de3a001 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -185254,144 +185254,7 @@ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - + @@ -185466,7 +185329,7 @@ - + @@ -185541,7 +185404,7 @@ - + @@ -185577,7 +185440,7 @@ - + @@ -185601,7 +185464,7 @@ - + @@ -185620,7 +185483,7 @@ - + @@ -185642,7 +185505,7 @@ - + @@ -185660,7 +185523,7 @@ - + @@ -185699,7 +185562,7 @@ - + @@ -185744,7 +185607,7 @@ - + @@ -185839,7 +185702,7 @@ - + @@ -185847,7 +185710,7 @@ - + @@ -185966,7 +185829,7 @@ - + @@ -185980,7 +185843,7 @@ - + @@ -185999,7 +185862,7 @@ - + @@ -186025,7 +185888,7 @@ - + @@ -186109,7 +185972,7 @@ - + @@ -186170,7 +186033,7 @@ - + @@ -186204,7 +186067,7 @@ - + @@ -186255,14 +186118,14 @@ - + - + @@ -186316,7 +186179,7 @@ - + @@ -186369,7 +186232,7 @@ - + @@ -186395,7 +186258,7 @@ - + @@ -186415,7 +186278,7 @@ - + @@ -186434,7 +186297,7 @@ - + @@ -186470,13 +186333,13 @@ - + - + @@ -186500,7 +186363,7 @@ - + @@ -186537,7 +186400,7 @@ - + @@ -186560,7 +186423,7 @@ - + @@ -186591,7 +186454,7 @@ - + @@ -186626,7 +186489,7 @@ - + @@ -186648,14 +186511,14 @@ - + - + @@ -186677,7 +186540,7 @@ - + @@ -186692,7 +186555,7 @@ - + @@ -186717,7 +186580,7 @@ - + @@ -186740,31 +186603,31 @@ - + - + - + - + - + @@ -186789,7 +186652,7 @@ - + @@ -187124,7 +186987,7 @@ - + @@ -187328,7 +187191,7 @@ - + @@ -187339,7 +187202,7 @@ - + @@ -187915,7 +187778,7 @@ - + @@ -187999,7 +187862,7 @@ - + @@ -188053,7 +187916,7 @@ - + @@ -188092,7 +187955,7 @@ - + @@ -188119,7 +187982,7 @@ - + @@ -188133,14 +187996,14 @@ - + - + @@ -188170,7 +188033,7 @@ - + @@ -188187,7 +188050,7 @@ - + @@ -188203,7 +188066,7 @@ - + @@ -188215,7 +188078,7 @@ - + @@ -188245,7 +188108,7 @@ - + @@ -188272,7 +188135,7 @@ - + @@ -188287,7 +188150,7 @@ - + @@ -188303,13 +188166,13 @@ - + - + @@ -188327,7 +188190,7 @@ - + @@ -188367,14 +188230,14 @@ - + - + @@ -188382,7 +188245,7 @@ - + @@ -188404,7 +188267,7 @@ - + @@ -188444,7 +188307,7 @@ - + @@ -188527,7 +188390,7 @@ - + @@ -189136,7 +188999,7 @@ - + @@ -189422,7 +189285,7 @@ - + @@ -189528,7 +189391,7 @@ - + @@ -189586,7 +189449,7 @@ - + @@ -189696,7 +189559,7 @@ - + @@ -189838,7 +189701,7 @@ - + @@ -189852,14 +189715,14 @@ - + - + @@ -189893,7 +189756,7 @@ - + @@ -190113,12 +189976,12 @@ - + - + @@ -190127,12 +189990,12 @@ - + - + @@ -190144,7 +190007,7 @@ - + @@ -190181,7 +190044,7 @@ - + @@ -190201,7 +190064,7 @@ - + @@ -190229,7 +190092,7 @@ - + @@ -190251,7 +190114,7 @@ - + @@ -190347,7 +190210,7 @@ - + @@ -190356,7 +190219,7 @@ - + diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index 730e567c..ca6bd781 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -41398,7 +41398,6 @@ - s_0064: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1552 - name: (S)-malate exchange @@ -41406,7 +41405,6 @@ - s_0067: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1553 - name: 1-(sn-glycero-3-phospho)-1D-myo-inositol exchange @@ -41601,7 +41599,6 @@ - s_0181: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1587 - name: 2-oxoglutarate transport @@ -41993,7 +41990,6 @@ - s_0364: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1635 - name: acetate transport @@ -42028,7 +42024,6 @@ - s_0384: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1640 - name: adenine transport @@ -42061,7 +42056,6 @@ - s_0387: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1644 - name: ADP transport @@ -42103,7 +42097,6 @@ - s_0408: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1650 - name: trehalose exchange @@ -42111,7 +42104,6 @@ - s_1521: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1651 - name: alpha-D-glucosamine 6-phosphate exchange @@ -42119,7 +42111,6 @@ - s_0413: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1652 - name: alpha-ketoglutarate/malate transporter @@ -42138,7 +42129,6 @@ - s_0420: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1656 - name: AMP transport @@ -42413,7 +42403,6 @@ - s_0523: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1688 - name: citrate/isocitrate antiport @@ -42526,7 +42515,6 @@ - s_0544: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1703 - name: cytidylate kinase (CMP) @@ -42556,7 +42544,6 @@ - s_0546: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1706 - name: D-arabinose exchange @@ -42564,7 +42551,6 @@ - s_0549: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1707 - name: D-arabinose transport @@ -42590,7 +42576,6 @@ - s_0554: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1710 - name: D-galactose exchange @@ -42598,7 +42583,6 @@ - s_0559: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1711 - name: D-galacturonate exchange @@ -42613,7 +42597,6 @@ - s_0562: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1713 - name: D-glucosamine 6-phosphate uniport @@ -42630,7 +42613,6 @@ - s_0565: -1 - lower_bound: -1 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1715 - name: D-mannose exchange @@ -42638,7 +42620,6 @@ - s_0572: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1716 - name: D-ribose exchange @@ -42646,7 +42627,6 @@ - s_0576: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1717 - name: D-sorbitol transport @@ -42663,7 +42643,6 @@ - s_0579: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1719 - name: D-xylose transport @@ -42755,7 +42734,6 @@ - s_0597: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1728 - name: deoxyadenosine transport @@ -43025,7 +43003,6 @@ - s_0681: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1762 - name: ethanol transport @@ -43171,7 +43148,6 @@ - s_0723: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1794 - name: formate transport @@ -43218,7 +43194,6 @@ - s_0726: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1800 - name: gamma-aminobutyrate exchange @@ -43226,7 +43201,6 @@ - s_0736: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1801 - name: GDP transport @@ -43278,7 +43252,6 @@ - s_0751: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1808 - name: glycerol exchange @@ -43286,7 +43259,6 @@ - s_0766: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1809 - name: glycerol-3-phosphate shuttle @@ -43305,7 +43277,6 @@ - s_1004: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1811 - name: glycine transport @@ -43347,7 +43318,6 @@ - s_0780: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1816 - name: glyoxylate transport @@ -43373,7 +43343,6 @@ - s_0788: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1819 - name: guanine transport @@ -43390,7 +43359,6 @@ - s_0791: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1821 - name: guanosine kinase @@ -43631,7 +43599,6 @@ - s_0857: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1848 - name: inosine transport @@ -43859,7 +43826,6 @@ - s_0956: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1874 - name: L-alanine transport @@ -43876,7 +43842,6 @@ - s_0962: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1876 - name: L-arabinitol transport @@ -43902,7 +43867,6 @@ - s_0964: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1879 - name: L-arginine exchange @@ -43910,7 +43874,6 @@ - s_0966: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1880 - name: L-asparagine exchange @@ -43918,7 +43881,6 @@ - s_0970: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1881 - name: L-aspartate exchange @@ -43926,7 +43888,6 @@ - s_0974: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1882 - name: L-carnitine transport @@ -43943,7 +43904,6 @@ - s_0982: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1884 - name: L-erythro-4-hydroxyglutamate transport @@ -43987,7 +43947,6 @@ - s_0992: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1890 - name: L-glutamate transport @@ -44004,7 +43963,6 @@ - s_1000: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1892 - name: L-glutamine transport @@ -44037,7 +43995,6 @@ - s_1015: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1897 - name: L-isoleucine exchange @@ -44045,7 +44002,6 @@ - s_1017: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1898 - name: L-isoleucine transport @@ -44062,7 +44018,6 @@ - s_1022: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1900 - name: L-lysine exchange @@ -44086,7 +44041,6 @@ - s_1030: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1903 - name: L-phenylalanine exchange @@ -44094,7 +44048,6 @@ - s_1033: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1904 - name: L-proline exchange @@ -44102,7 +44055,6 @@ - s_1036: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1905 - name: L-proline transport @@ -44119,7 +44071,6 @@ - s_1041: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1907 - name: L-serine transport @@ -44161,7 +44112,6 @@ - s_1046: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1912 - name: L-tryptophan exchange @@ -44169,7 +44119,6 @@ - s_1049: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1913 - name: L-tyrosine exchange @@ -44177,7 +44126,6 @@ - s_1052: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1914 - name: L-valine exchange @@ -44185,7 +44133,6 @@ - s_1057: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1915 - name: lanosterol exchange @@ -44317,7 +44264,6 @@ - s_1106: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1932 - name: mannan transport @@ -44619,7 +44565,6 @@ - s_1267: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_1988 - name: oxaloacetate transport @@ -44769,7 +44714,6 @@ - s_1324: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_2008 - name: phosphate transport @@ -44908,7 +44852,6 @@ - s_1400: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_2034 - name: pyruvate transport @@ -45079,7 +45022,6 @@ - s_1459: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_2057 - name: succinate transport @@ -45096,7 +45038,6 @@ - s_1466: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_2060 - name: sulphate exchange @@ -45104,7 +45045,6 @@ - s_1468: -1 - lower_bound: -1000 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_2061 - name: sulphite exchange @@ -45357,7 +45297,6 @@ - s_1553: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_2092 - name: uridine exchange @@ -45467,7 +45406,6 @@ - s_1567: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_2105 - name: xylitol transport @@ -75101,7 +75039,6 @@ - s_3715: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4044 - name: melibiose exchange @@ -80960,7 +80897,6 @@ - s_4170: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4497 - name: 3-oxalomalate(3-) exchange @@ -80968,7 +80904,6 @@ - s_4137: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4498 - name: 6-O-alpha-D-glucopyranosyl-D-fructofuranose exchange @@ -80976,7 +80911,6 @@ - s_4109: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4499 - name: 5-dehydro-D-gluconate exchange @@ -80984,7 +80918,6 @@ - s_4118: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4500 - name: D-tagatose exchange @@ -80992,7 +80925,6 @@ - s_4130: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4501 - name: turanose exchange @@ -81000,7 +80932,6 @@ - s_4131: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4502 - name: D-glucose 6-phosphate exchange @@ -81008,7 +80939,6 @@ - s_4150: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4503 - name: alpha-maltotriose exchange @@ -81016,7 +80946,6 @@ - s_4140: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4504 - name: D-glucose 1-phosphate exchange @@ -81024,7 +80953,6 @@ - s_4145: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4505 - name: methyl alpha-D-glucopyranoside exchange @@ -81032,7 +80960,6 @@ - s_4125: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4506 - name: D-Glucosamine exchange @@ -81040,7 +80967,6 @@ - s_4164: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4507 - name: glycerone exchange @@ -81048,7 +80974,6 @@ - s_4167: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4508 - name: Ala-Gln exchange @@ -81056,7 +80981,6 @@ - s_4034: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4509 - name: Ala-Leu exchange @@ -81064,7 +80988,6 @@ - s_4168: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4510 - name: Gly-Gln exchange @@ -81072,7 +80995,6 @@ - s_4056: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4511 - name: Ala-His exchange @@ -81080,7 +81002,6 @@ - s_4050: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4512 - name: Gly-Asn exchange @@ -81088,7 +81009,6 @@ - s_4053: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4513 - name: Ala-Glu exchange @@ -81096,7 +81016,6 @@ - s_4037: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4514 - name: Gly-Met exchange @@ -81104,7 +81023,6 @@ - s_4085: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4515 - name: Ala-Asp exchange @@ -81112,7 +81030,6 @@ - s_4119: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4516 - name: Gly-Glu exchange @@ -81120,7 +81037,6 @@ - s_4059: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4517 - name: Ala-Thr exchange @@ -81128,7 +81044,6 @@ - s_4040: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4518 - name: Met-Ala exchange @@ -81136,7 +81051,6 @@ - s_4143: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4519 - name: L-citrulline exchange @@ -81144,7 +81058,6 @@ - s_4166: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4520 - name: 2-aminobutanoate exchange @@ -81152,7 +81065,6 @@ - s_4080: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4521 - name: choline phosphate exchange @@ -81160,7 +81072,6 @@ - s_4158: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4522 - name: glycerol 1-phosphate exchange @@ -81168,7 +81079,6 @@ - s_4049: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4523 - name: 2-phospho-D-glyceric acid exchange @@ -81176,7 +81086,6 @@ - s_4141: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4524 - name: GMP exchange @@ -81184,7 +81093,6 @@ - s_4148: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4525 - name: 3-phospho-serine exchange @@ -81192,7 +81100,6 @@ - s_4147: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4526 - name: O-phosphonatooxy-D-serine(2-) exchange @@ -81200,7 +81107,6 @@ - s_4078: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4527 - name: diphosphate exchange @@ -81208,7 +81114,6 @@ - s_4157: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4528 - name: triphosphate exchange @@ -81216,7 +81121,6 @@ - s_4099: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4529 - name: phosphoenolpyruvate exchange @@ -81224,7 +81128,6 @@ - s_4152: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4530 - name: N(omega)-phospho-L-arginine exchange @@ -81232,7 +81135,6 @@ - s_4093: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4531 - name: carbamoyl phosphate exchange @@ -81240,7 +81142,6 @@ - s_4146: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4532 - name: O-phosphoethanolamine exchange @@ -81248,7 +81149,6 @@ - s_4154: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4533 - name: cysteamine S-phosphate exchange @@ -81256,7 +81156,6 @@ - s_4075: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4534 - name: guanosine 2'-monophosphate exchange @@ -81264,7 +81163,6 @@ - s_4067: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4535 - name: glycerol 2-phosphate(2-) exchange @@ -81272,7 +81170,6 @@ - s_4063: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4536 - name: 3'-GMP exchange @@ -81280,7 +81177,6 @@ - s_4069: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4537 - name: 2-phosphoglycolate exchange @@ -81288,7 +81184,6 @@ - s_4070: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4538 - name: 6-phospho-D-gluconate exchange @@ -81296,7 +81191,6 @@ - s_4155: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4539 - name: D-mannose 6-phosphate exchange @@ -81304,7 +81198,6 @@ - s_4153: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4540 - name: 2',3'-cyclic GMP exchange @@ -81312,7 +81205,6 @@ - s_4095: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4541 - name: O(4)-phospho-L-tyrosine exchange @@ -81320,7 +81212,6 @@ - s_4097: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4542 - name: O-phospho-L-threonine exchange @@ -81328,7 +81219,6 @@ - s_4065: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4543 - name: 3-phosphonato-D-glycerate(3-) exchange @@ -81336,7 +81226,6 @@ - s_4142: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4544 - name: adenosine 2'-phosphate exchange @@ -81344,7 +81233,6 @@ - s_4162: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4545 - name: 3'-AMP exchange @@ -81352,7 +81240,6 @@ - s_4107: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4546 - name: 2',3'-cyclic AMP exchange @@ -81360,7 +81247,6 @@ - s_4161: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4547 - name: D-mannose 1-phosphate exchange @@ -81368,7 +81254,6 @@ - s_4156: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4548 - name: AMP exchange @@ -81376,7 +81261,6 @@ - s_4160: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4549 - name: N(alpha)-acetyl-L-methionine exchange @@ -81384,7 +81268,6 @@ - s_4135: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4550 - name: L-Methionine S-oxide exchange @@ -81392,7 +81275,6 @@ - s_4176: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4551 - name: 3-sulfino-L-alanine exchange @@ -81400,7 +81282,6 @@ - s_4105: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4552 - name: N-acetyl-L-cysteine exchange @@ -81408,7 +81289,6 @@ - s_4111: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4553 - name: L-cysteate exchange @@ -81416,7 +81296,6 @@ - s_4139: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4554 - name: 2-hydroxyethane-1-sulfonate exchange @@ -81424,7 +81303,6 @@ - s_4116: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4555 - name: acetoacetate exchange @@ -81432,7 +81310,6 @@ - s_4133: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4556 - name: N-acetyl-L-glutamate exchange @@ -81440,7 +81317,6 @@ - s_4172: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4557 - name: UMP exchange @@ -81448,7 +81324,6 @@ - s_4151: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4558 - name: CMP exchange @@ -81456,7 +81331,6 @@ - s_4163: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4559 - name: thymidine 5'-monophosphate exchange @@ -81464,7 +81338,6 @@ - s_4047: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4560 - name: thymidine 3'-monophosphate exchange @@ -81472,7 +81345,6 @@ - s_4045: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4561 - name: cytidine 2'-phosphate exchange @@ -81480,7 +81352,6 @@ - s_4101: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4562 - name: uridine 2'-phosphate exchange @@ -81488,7 +81359,6 @@ - s_4082: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4563 - name: 3'-UMP exchange @@ -81496,7 +81366,6 @@ - s_4084: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4564 - name: 2',3'-cyclic CMP exchange @@ -81504,7 +81373,6 @@ - s_4127: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - !!omap - id: r_4565 - name: 2',3'-cyclic UMP exchange @@ -81512,7 +81380,6 @@ - s_4103: -1 - lower_bound: 0 - upper_bound: 1000 - - subsystem: Exchange - genes: - !!omap - id: Q0045 From 73ba9166a0d7f6c9a8d28f6a4ebc37397220be5d Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Mon, 27 Aug 2018 16:44:28 +0200 Subject: [PATCH 14/27] fix-rxn.prop: confidence scores some scores were left out in the previous commit --- .../modelCuration/addBiologRxnToGEM.m | 10 +- ModelFiles/xml/yeastGEM.xml | 268 +++++++++--------- ModelFiles/yml/yeastGEM.yml | 268 +++++++++--------- 3 files changed, 274 insertions(+), 272 deletions(-) diff --git a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m index f5411a50..2aeeb096 100644 --- a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m +++ b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m @@ -94,7 +94,7 @@ [~,metID] = ismember(newmet.metNames(i),model.metNames); if metID ~= 0 model.metFormulas{metID} = newmet.metFormulas{i}; - model.metCharges(metID) = newmet.metCharges(i); + model.metCharges(metID) = newmet.metCharges(i); model.metKEGGID{metID} = newmet.metKEGGID{i}; model.metChEBIID{metID} = newmet.metChEBIID{i}; model.metNotes{metID} = newmet.metNotes{i}; @@ -111,8 +111,7 @@ j = find(strcmp(matrix.rxnIDs,newrxn.ID{i})); Met = matrix.mets(j); Coef = transpose(matrix.metcoef(j)); - model = addReaction(model,... - ['r_' newID],... + [model,dupIndex] = addReaction(model, ['r_' newID],... 'reactionName', newrxn.ID{i},... 'metaboliteList',Met,... 'stoichCoeffList',Coef,... @@ -121,6 +120,10 @@ 'checkDuplicate',1); [EnergyResults,RedoxResults] = CheckEnergyProduction(model,{['r_' newID]},EnergyResults,RedoxResults); [MassChargeresults] = CheckBalanceforSce(model,{['r_' newID]},MassChargeresults); + if isempty(dupIndex) + dupIndex = strcmp(model.rxns,['r_' newID]); + end + model.rxnConfidenceScores(dupIndex) = 1; %reactions without gene but needed for modelling end % Add gene standard name for new genes: @@ -149,7 +152,6 @@ model.rxnNames{rxnID} = newrxn.rxnNames{i}; model.rxnECNumbers(rxnID) = newrxn.rxnECNumbers(i); model.rxnKEGGID(rxnID) = newrxn.rxnKEGGID(i); - model.rxnConfidenceScores(rxnID) = 1; %reactions without gene but needed for modelling end end diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index 2de3a001..bd71284a 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -178357,7 +178357,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -178381,7 +178381,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

+

Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

 @@ -181642,7 +181642,7 @@ -

Confidence Level: 0

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Confidence Level: 1

 @@ -181668,7 +181668,7 @@ -

Confidence Level: 0

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Confidence Level: 1

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Confidence Level: 0

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Confidence Level: 1

 @@ -181718,7 +181718,7 @@ -

Confidence Level: 0

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Confidence Level: 1

 @@ -181742,7 +181742,7 @@ -

Confidence Level: 0

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Confidence Level: 1

 @@ -181768,7 +181768,7 @@ -

Confidence Level: 0

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Confidence Level: 1

 @@ -181792,7 +181792,7 @@ -

Confidence Level: 0

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Confidence Level: 1

 @@ -181818,7 +181818,7 @@ -

Confidence Level: 0

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Confidence Level: 1

 @@ -181844,7 +181844,7 @@ -

Confidence Level: 0

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Confidence Level: 1

 @@ -181892,7 +181892,7 @@ -

Confidence Level: 0

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Confidence Level: 1

 @@ -181918,7 +181918,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -181994,7 +181994,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182020,7 +182020,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182070,7 +182070,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182094,7 +182094,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182120,7 +182120,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182144,7 +182144,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182170,7 +182170,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182222,7 +182222,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182248,7 +182248,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182274,7 +182274,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182314,7 +182314,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182346,7 +182346,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182378,7 +182378,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182408,7 +182408,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182441,7 +182441,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182474,7 +182474,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182534,7 +182534,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182567,7 +182567,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182591,7 +182591,7 @@ -

Confidence Level: 0

+

Confidence Level: 1

 @@ -182612,7 +182612,7 @@ -

Confidence Level: 0

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Confidence Level: 1

 diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index ca6bd781..9e3ef95f 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -79106,7 +79106,7 @@ - s_4063: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4342 - name: Glycerol-2-phosphate phosphohydrolase @@ -79120,7 +79120,7 @@ - annotation: !!omap - ec-code: 3.1.3.19 - kegg.reaction: R01043 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4343 - name: L-Threonine phosphate transport in via proton symport @@ -79131,7 +79131,7 @@ - s_4065: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4344 - name: acid phosphatase / phosphotransferase @@ -79144,7 +79144,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.3.- - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4345 - name: alkaline phosphatase @@ -79157,7 +79157,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.3.- - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4346 - name: Guanosine transport via proton symport @@ -79182,7 +79182,7 @@ - annotation: !!omap - ec-code: 3.1.3.6 - kegg.reaction: R02148 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4348 - name: Guanosine transport via proton symport(for 3'-GMP) @@ -79204,7 +79204,7 @@ - s_4071: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4350 - name: 2-phosphoglycolate phosphohydrolase @@ -79218,7 +79218,7 @@ - annotation: !!omap - ec-code: 3.1.3.18 - kegg.reaction: R01334 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4351 - name: alkaline phosphatase @@ -79231,7 +79231,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.3.- - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4352 - name: cysteamine S-phosphate transport via proton symport @@ -79254,7 +79254,7 @@ - annotation: !!omap - ec-code: 1.13.11.19 - kegg.reaction: R02467 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4354 - name: hypotaurine:NAD+ oxidoreductase @@ -79270,7 +79270,7 @@ - annotation: !!omap - ec-code: 1.8.1.3 - kegg.reaction: R01681 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4355 - name: 2-aminobutanoate:2-oxoglutarate aminotransferase @@ -79284,7 +79284,7 @@ - annotation: !!omap - ec-code: 2.6.1.42 - kegg.reaction: R10991 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4356 - name: 2-aminobutyrate transport @@ -79308,7 +79308,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.3.- - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4358 - name: Uridine 2'-phosphate transport in via proton symport @@ -79319,7 +79319,7 @@ - s_4082: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4359 - name: Uridine 3'-monophosphate phosphohydrolase @@ -79333,7 +79333,7 @@ - annotation: !!omap - ec-code: 3.1.3.6 - kegg.reaction: R01877 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4360 - name: 3'-UMP transport in via proton symport @@ -79344,7 +79344,7 @@ - s_4084: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4361 - name: Gly-Met transport via proton symport @@ -79355,7 +79355,7 @@ - s_4086: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4362 - name: dipeptidase @@ -79368,7 +79368,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.4.13.18 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4363 - name: R07420 @@ -79380,7 +79380,7 @@ - upper_bound: 1000 - annotation: !!omap - kegg.reaction: R07420 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4364 - name: N-phosphocreatine transport @@ -79417,7 +79417,7 @@ - annotation: !!omap - ec-code: 2.7.3.3 - kegg.reaction: R00554 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4367 - name: L-arginine phosphate transport in/out via proton symport @@ -79428,7 +79428,7 @@ - s_4093: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4368 - name: acid phosphatase / phosphotransferase @@ -79439,7 +79439,7 @@ - s_4096: -1 - lower_bound: 0 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4369 - name: Tripolyphosphate transport in via proton symport @@ -79450,7 +79450,7 @@ - s_4099: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4370 - name: alkaline phosphatase @@ -79463,7 +79463,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.3.- - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4371 - name: Cytidine- 2'- Monophosphate transport in via proton symport @@ -79474,7 +79474,7 @@ - s_4101: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4372 - name: cyclic phosphodiesterase @@ -79487,7 +79487,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.4.37 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4373 - name: 2',3'-Cyclic UMP transport in via proton symport @@ -79498,7 +79498,7 @@ - s_4103: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4374 - name: 3-Sulfino-L-alanine 4-carboxy-lyase @@ -79512,7 +79512,7 @@ - annotation: !!omap - ec-code: 3.13.1.- - kegg.reaction: R00863 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4375 - name: 3-Sulfino-L-alanine transport via proton antiport @@ -79523,7 +79523,7 @@ - s_4105: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4376 - name: adenosine 3'-phosphate phosphohydrolase @@ -79537,7 +79537,7 @@ - annotation: !!omap - ec-code: 3.1.3.6 - kegg.reaction: R01562 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4377 - name: 3AMP transport via diffusion (extracellular to periplasm) @@ -79546,7 +79546,7 @@ - s_4107: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4378 - name: α-glucosidase @@ -79559,7 +79559,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.2.1.20 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4379 - name: Palatinose transport in via proton symport @@ -79570,7 +79570,7 @@ - s_4109: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4380 - name: Amino-Acid N-Acetyltransferase @@ -79582,7 +79582,7 @@ - s_4110: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4381 - name: Acetylcysteine transport via proton symport @@ -79593,7 +79593,7 @@ - s_4111: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4382 - name: thiosulfate:ferricytochrome-c oxidoreductase @@ -79606,7 +79606,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 1.8.2.2 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4383 - name: etrathionate transport via diffusion @@ -79615,7 +79615,7 @@ - s_4114: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4384 - name: D-Gluconate:NADP+ 5-oxidoreductase @@ -79632,7 +79632,7 @@ - 1.1.1.- - 1.1.1.69 - kegg.reaction: R01740 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4385 - name: 5-Dehydro-D-gluconate transport via proton symport @@ -79643,7 +79643,7 @@ - s_4118: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4386 - name: dipeptidase @@ -79656,7 +79656,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.4.13.18 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4387 - name: ala-L-asp-L transport via proton symport @@ -79667,7 +79667,7 @@ - s_4120: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4388 - name: cyclic phosphodiesterase @@ -79680,7 +79680,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.4.37 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4389 - name: 2',3'-Cyclic CMP transport in via proton symport @@ -79691,7 +79691,7 @@ - s_4127: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4390 - name: beta-glucosidase (methyl-alpha-D-glucoside) @@ -79704,7 +79704,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.2.1.21 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4391 - name: Methanol diffusion @@ -79713,7 +79713,7 @@ - s_4124: 1 - lower_bound: 0 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4392 - name: alpha-Methyl-D-glucoside transport via proton symport @@ -79724,7 +79724,7 @@ - s_4125: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4393 - name: ATP:D-tagatose 6-phosphotransferase @@ -79738,7 +79738,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 2.7.1.101 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4394 - name: D-tagatose 6-phosphate 4-epimerase @@ -79747,7 +79747,7 @@ - s_4129: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4395 - name: D-tagatose uptake via diffusion @@ -79756,7 +79756,7 @@ - s_4130: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4396 - name: Acetoacetate:CoA ligase (AMP-forming) @@ -79772,7 +79772,7 @@ - annotation: !!omap - ec-code: 6.2.1.16 - kegg.reaction: R01357 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4397 - name: N-Acyl-Aliphatic-L-Amino Acid Amidohydrolase @@ -79785,7 +79785,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.5.1.14 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4398 - name: Ala-Gln transport via proton symport @@ -79796,7 +79796,7 @@ - s_4035: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4399 - name: L-alanyl-L-glutamate transport in via proton symport @@ -79807,7 +79807,7 @@ - s_4039: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4400 - name: Maltodextrin glucosidase (maltotriose) @@ -79820,7 +79820,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.2.1.20 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4401 - name: Ala-Thr transport via proton symport @@ -79831,7 +79831,7 @@ - s_4042: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4402 - name: Ala-Thr transport via proton symport @@ -79842,7 +79842,7 @@ - s_4041: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4403 - name: Triphosphate phosphohydrolase @@ -79857,7 +79857,7 @@ - annotation: !!omap - ec-code: 3.6.1.25 - kegg.reaction: R00138 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4404 - name: Gly-Asn transport via proton symport @@ -79868,7 +79868,7 @@ - s_4054: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4405 - name: glycerol 1-phosphate transport @@ -79888,7 +79888,7 @@ - s_4078: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4407 - name: D-O-Phosphoserine phosphohydrolase @@ -79902,7 +79902,7 @@ - annotation: !!omap - ec-code: 3.1.3.3 - kegg.reaction: R02853 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4408 - name: L-alanyl-L-glutamate transport in via proton symport @@ -79913,7 +79913,7 @@ - s_4038: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4409 - name: L-alanyl-gamma-L-glutamate peptidase @@ -79926,7 +79926,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.4.13.18 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4410 - name: 3-oxalomalate glyoxylate-lyase (oxaloacetate-forming) @@ -79939,7 +79939,7 @@ - annotation: !!omap - ec-code: 4.1.3.13 - kegg.reaction: R00477 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4411 - name: L-cysteate bisulfite-lyase (deaminating) @@ -79954,7 +79954,7 @@ - annotation: !!omap - ec-code: 4.4.1.25 - kegg.reaction: R07634 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4412 - name: cyclic phosphodiesterase @@ -79967,7 +79967,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.4.37 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4413 - name: deoxynucleotide 3'-phosphatase @@ -79980,7 +79980,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.3.34 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4414 - name: cytosol nonspecific dipeptidase @@ -79993,7 +79993,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.4.13.18 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4415 - name: Cytosol non-specific dipeptidase @@ -80006,7 +80006,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.4.13.18 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4416 - name: Cytosol non-specific dipeptidase @@ -80019,7 +80019,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.4.13.18 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4417 - name: Cytosol non-specific dipeptidase @@ -80032,7 +80032,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.4.13.18 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4418 - name: Cytosol non-specific dipeptidase @@ -80045,7 +80045,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.4.13.18 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4419 - name: L-Cysteate transport via proton symport @@ -80056,7 +80056,7 @@ - s_4139: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4420 - name: alpha-glucosidase @@ -80069,7 +80069,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.2.1.20 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4421 - name: 2-Hydroxyethanesulfonate transport via proton symport @@ -80080,7 +80080,7 @@ - s_4116: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4422 - name: 3-Oxalomalate transport via proton symport @@ -80091,7 +80091,7 @@ - s_4137: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4423 - name: Gly-Met transport via proton symport @@ -80102,7 +80102,7 @@ - s_4087: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4424 - name: Gly-Gln transport via proton symport @@ -80113,7 +80113,7 @@ - s_4057: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4425 - name: Gly-Gln transport via proton symport @@ -80124,7 +80124,7 @@ - s_4058: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4426 - name: Ala-Gln transport via proton symport @@ -80135,7 +80135,7 @@ - s_4036: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4427 - name: N-Acetylmethionine transport via proton symport @@ -80146,7 +80146,7 @@ - s_4135: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4428 - name: Phosphotyrosine transport via proton symport @@ -80157,7 +80157,7 @@ - s_4097: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4429 - name: Ala-His transport via proton symport @@ -80168,7 +80168,7 @@ - s_4051: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4430 - name: Ala-His transport via proton symport @@ -80179,7 +80179,7 @@ - s_4052: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4431 - name: ala-L-asp-L transport via proton symport @@ -80190,7 +80190,7 @@ - s_4121: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4432 - name: FMNH2-dependent alkanesulfonate monooxygenase @@ -80207,7 +80207,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 1.14.14.5 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4433 - name: thymidine 3-monophosphate transport @@ -80216,7 +80216,7 @@ - s_4045: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4434 - name: thymidine 5-monophosphate transport @@ -80225,7 +80225,7 @@ - s_4047: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4435 - name: glycerol-1-phosphate phosphohydrolase @@ -80239,7 +80239,7 @@ - gene_reaction_rule: YIL053W or YER062C - annotation: !!omap - kegg.reaction: R08658 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4436 - name: nucleotide-specific phosphatase (thymidine 5'-monophosphate) @@ -80285,7 +80285,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.4.13.18 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4440 - name: L-methionine transport, vacuoluar @@ -80320,7 +80320,7 @@ - s_4095: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4444 - name: D-Glycerate 2-phosphate transport in/out via proton symport @@ -80331,7 +80331,7 @@ - s_4141: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4445 - name: 3-Phospho-D-glycerate transport in/out via proton symport @@ -80342,7 +80342,7 @@ - s_4142: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4446 - name: D-glucose 1-phosphate transport via diffusion @@ -80351,7 +80351,7 @@ - s_4145: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4447 - name: carbamoyl phosphate nuclear transport via diffusion @@ -80360,7 +80360,7 @@ - s_4146: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4448 - name: Met-Ala transport via proton symport (excelluar to cytosol) @@ -80393,7 +80393,7 @@ - s_4147: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4451 - name: GMP transport via proton symport @@ -80404,7 +80404,7 @@ - s_4148: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4452 - name: myo-inositol phosphate transport via diffusion (extracellular to periplasm) @@ -80413,7 +80413,7 @@ - s_4149: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4453 - name: Exchange rxns for g6p @@ -80422,7 +80422,7 @@ - s_4150: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4454 - name: UMP transport @@ -80431,7 +80431,7 @@ - s_4151: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4455 - name: Phosphoenolpyruvate transport in via proton symport @@ -80442,7 +80442,7 @@ - s_4152: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4456 - name: Mannose 6-phosphate transport via diffusion (extracellular to periplasm) @@ -80451,7 +80451,7 @@ - s_4153: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4457 - name: O-Phosphoryl-Ethanolamine transport in via proton symport @@ -80462,7 +80462,7 @@ - s_4154: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4458 - name: 6-Phospho-D-gluconate transport in/out via proton symport @@ -80473,7 +80473,7 @@ - s_4155: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4459 - name: MAN1P transport in/out via proton symport @@ -80484,7 +80484,7 @@ - s_4156: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4460 - name: Pyrophosphate transport in via proton symport @@ -80495,7 +80495,7 @@ - s_4157: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4461 - name: Choline phosphate intracellular transport @@ -80504,7 +80504,7 @@ - s_4158: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4462 - name: thiosulfate transport @@ -80513,7 +80513,7 @@ - s_4159: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4463 - name: AMP transport in/out via proton symport @@ -80524,7 +80524,7 @@ - s_4160: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4464 - name: 23cAMP transport via diffusion (extracellular to periplasm) @@ -80533,7 +80533,7 @@ - s_4161: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4465 - name: Adenosine- 2'-Monophosphate transport in via proton symport @@ -80544,7 +80544,7 @@ - s_4162: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4466 - name: CMP transport in/out via proton symport @@ -80555,7 +80555,7 @@ - s_4163: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4467 - name: D-glucosamine transport via diffusion (extracellular to periplasm) @@ -80564,7 +80564,7 @@ - s_4164: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4468 - name: 2-deoxy-D-ribose transport @@ -80584,7 +80584,7 @@ - s_4166: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4470 - name: Dihydroxyacetone transport via facilitated diffusion @@ -80593,7 +80593,7 @@ - s_4167: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4471 - name: Ala-Leu transport via proton symport (excelluar to cytosol) @@ -80626,7 +80626,7 @@ - s_4171: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4474 - name: L-alanylglycine transport via proton antiport @@ -80637,7 +80637,7 @@ - s_4171: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4475 - name: N-acetyl-L-glutamate transport @@ -80655,7 +80655,7 @@ - s_4173: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4477 - name: Lipoamide transport via proton symport @@ -80666,7 +80666,7 @@ - s_4175: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4478 - name: L-methionine S-oxide diffusion (extracellular) @@ -80675,7 +80675,7 @@ - s_4176: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4479 - name: Gly-Asn transport via proton symport @@ -80686,7 +80686,7 @@ - s_4055: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4480 - name: Cysteamine transport via proton antiport @@ -80697,7 +80697,7 @@ - s_4074: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4481 - name: Hydrogen sulfide oxidation @@ -80719,7 +80719,7 @@ - s_3759: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4483 - name: Glycine mitochondrial transport @@ -80730,7 +80730,7 @@ - s_3839: 1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4484 - name: O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) @@ -80747,7 +80747,7 @@ - 2.5.1.- - 2.5.1.48 - kegg.reaction: R01288 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4485 - name: 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) @@ -80761,7 +80761,7 @@ - annotation: !!omap - ec-code: 1.13.11.27 - kegg.reaction: R02521 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4486 - name: Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) @@ -80775,7 +80775,7 @@ - annotation: !!omap - ec-code: 1.13.11.5 - kegg.reaction: R02519 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4487 - name: 4-Maleylacetoacetate cis-trans-isomerase @@ -80787,7 +80787,7 @@ - annotation: !!omap - ec-code: 5.2.1.2 - kegg.reaction: R03181 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4488 - name: 4-fumarylacetoacetate fumarylhydrolase @@ -80802,7 +80802,7 @@ - annotation: !!omap - ec-code: 3.7.1.2 - kegg.reaction: R01364 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4489 - name: L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming) @@ -80817,7 +80817,7 @@ - annotation: !!omap - ec-code: 1.1.1.12 - kegg.reaction: R01903 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4490 - name: Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) @@ -80832,7 +80832,7 @@ - annotation: !!omap - ec-code: 1.1.1.10 - kegg.reaction: R01904 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4491 - name: arabinose reductase (D-arabinose) @@ -80859,7 +80859,7 @@ - annotation: !!omap - ec-code: 1.1.1.11 - kegg.reaction: R05604 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4493 - name: Acetoacetate transport via diffusion @@ -80868,7 +80868,7 @@ - s_4133: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4494 - name: Exchange rxns for meoh @@ -80876,7 +80876,7 @@ - s_4124: -1 - lower_bound: -1000 - upper_bound: 1000 - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4495 - name: alkaline phosphatase @@ -80889,7 +80889,7 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.3.- - - confidence_score: 0 + - confidence_score: 1 - !!omap - id: r_4496 - name: Ala-Gly exchange From 3789192bab5d1685da1a785e594f493b18e7592e Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Tue, 28 Aug 2018 12:34:56 +0200 Subject: [PATCH 15/27] fix-met.annot: metaNetX IDs moved metabolite metaNetX ids from notes to proper COBRA field --- .../modelCuration/addBiologRxnToGEM.m | 26 +- ModelFiles/xml/yeastGEM.xml | 888 +++--------------- ModelFiles/yml/yeastGEM.yml | 148 +++ README.md | 2 +- 4 files changed, 311 insertions(+), 753 deletions(-) diff --git a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m index 2aeeb096..138a462e 100644 --- a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m +++ b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m @@ -82,22 +82,24 @@ % Add metabolite data: fid = fopen('../../ComplementaryData/modelCuration/Biolog_newRxnMetAnnotation.tsv'); -newmet_annot = textscan(fid,'%s %s %s %s %s %s %s','Delimiter','\t','HeaderLines',1); -newmet.metNames = newmet_annot{1}; -newmet.metFormulas = newmet_annot{2}; -newmet.metCharges = cellfun(@str2num, newmet_annot{3}); -newmet.metKEGGID = newmet_annot{5}; -newmet.metChEBIID = newmet_annot{6}; -newmet.metNotes = newmet_annot{7}; +newmet_annot = textscan(fid,'%s %s %s %s %s %s %s','Delimiter','\t','HeaderLines',1); +newmet.metNames = newmet_annot{1}; +newmet.metFormulas = newmet_annot{2}; +newmet.metCharges = cellfun(@str2num, newmet_annot{3}); +newmet.metKEGGID = newmet_annot{5}; +newmet.metChEBIID = newmet_annot{6}; +newmet.metMetaNetXID = newmet_annot{7}; + fclose(fid); for i = 1:length(newmet.metNames) [~,metID] = ismember(newmet.metNames(i),model.metNames); if metID ~= 0 - model.metFormulas{metID} = newmet.metFormulas{i}; - model.metCharges(metID) = newmet.metCharges(i); - model.metKEGGID{metID} = newmet.metKEGGID{i}; - model.metChEBIID{metID} = newmet.metChEBIID{i}; - model.metNotes{metID} = newmet.metNotes{i}; + model.metFormulas{metID} = newmet.metFormulas{i}; + model.metCharges(metID) = newmet.metCharges(i); + model.metKEGGID{metID} = newmet.metKEGGID{i}; + model.metChEBIID{metID} = newmet.metChEBIID{i}; + model.metMetaNetXID{metID} = newmet.metMetaNetXID{i}; + model.metNotes{metID} = ''; end end diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index bd71284a..8a9f9fbf 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -46210,17 +46210,13 @@ - - -

NOTES: MNXM40495

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NOTES: MNXM40495

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NOTES: MNXM40495

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NOTES: MNXM4026

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NOTES: MNXM40497

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NOTES: MNXM40497

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NOTES: MNXM40496

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NOTES: MNXM40496

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NOTES: MNXM48297

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NOTES: MNXM726

- - @@ -47204,6 +47031,7 @@ + @@ -47216,11 +47044,6 @@ - - -

NOTES: MNXM4752

- - @@ -47228,6 +47051,7 @@ + @@ -47240,11 +47064,6 @@ - - -

NOTES: MNXM4752

- - @@ -47252,6 +47071,7 @@ + @@ -47264,17 +47084,13 @@ - - -

NOTES: MNXM15850

- - + @@ -47287,17 +47103,13 @@ - - -

NOTES: MNXM15850

- - + @@ -47310,11 +47122,6 @@ - - -

NOTES: MNXM13238

- - @@ -47322,6 +47129,7 @@ + @@ -47334,11 +47142,6 @@ - - -

NOTES: MNXM13238

- - @@ -47346,6 +47149,7 @@ + @@ -47358,11 +47162,6 @@ - - -

NOTES: MNXM2184

- - @@ -47370,6 +47169,7 @@ + @@ -47382,11 +47182,6 @@ - - -

NOTES: MNXM2184

- - @@ -47394,6 +47189,7 @@ + @@ -47406,17 +47202,13 @@ - - -

NOTES: MNXM55287

- - + @@ -47429,17 +47221,13 @@ - - -

NOTES: MNXM55287

- - + @@ -47452,17 +47240,13 @@ - - -

NOTES: MNXM55287

- - + @@ -47475,17 +47259,13 @@ - - -

NOTES: MNXM819

- - + @@ -47498,11 +47278,6 @@ - - -

NOTES: MNXM1470

- - @@ -47510,6 +47285,7 @@ + @@ -47522,17 +47298,13 @@ - - -

NOTES: MNXM819

- - + @@ -47545,11 +47317,6 @@ - - -

NOTES: MNXM1470

- - @@ -47557,6 +47324,7 @@ + @@ -47569,11 +47337,6 @@ - - -

NOTES: MNXM3663

- - @@ -47581,6 +47344,7 @@ + @@ -47593,11 +47357,6 @@ - - -

NOTES: MNXM3663

- - @@ -47605,6 +47364,7 @@ + @@ -47617,11 +47377,6 @@ - - -

NOTES: MNXM3149

- - @@ -47629,6 +47384,7 @@ + @@ -47641,11 +47397,6 @@ - - -

NOTES: MNXM3149

- - @@ -47653,6 +47404,7 @@ + @@ -47665,11 +47417,6 @@ - - -

NOTES: MNXM3323

- - @@ -47677,6 +47424,7 @@ + @@ -47689,11 +47437,6 @@ - - -

NOTES: MNXM3323

- - @@ -47701,6 +47444,7 @@ + @@ -47713,11 +47457,6 @@ - - -

NOTES: MNXM332

- - @@ -47725,6 +47464,7 @@ + @@ -47737,11 +47477,6 @@ - - -

NOTES: MNXM332

- - @@ -47749,6 +47484,7 @@ + @@ -47761,11 +47497,6 @@ - - -

NOTES: MNXM11237

- - @@ -47773,6 +47504,7 @@ + @@ -47785,11 +47517,6 @@ - - -

NOTES: MNXM11237

- - @@ -47797,6 +47524,7 @@ + @@ -47809,11 +47537,6 @@ - - -

NOTES: MNXM3150

- - @@ -47821,6 +47544,7 @@ + @@ -47833,11 +47557,6 @@ - - -

NOTES: MNXM3150

- - @@ -47845,6 +47564,7 @@ + @@ -47857,11 +47577,6 @@ - - -

NOTES: MNXM498

- - @@ -47869,6 +47584,7 @@ + @@ -47881,11 +47597,6 @@ - - -

NOTES: MNXM498

- - @@ -47893,6 +47604,7 @@ + @@ -47905,11 +47617,6 @@ - - -

NOTES: MNXM1985

- - @@ -47917,6 +47624,7 @@ + @@ -47929,11 +47637,6 @@ - - -

NOTES: MNXM1985

- - @@ -47941,6 +47644,7 @@ + @@ -47953,11 +47657,6 @@ - - -

NOTES: MNXM3518

- - @@ -47965,6 +47664,7 @@ + @@ -47977,11 +47677,6 @@ - - -

NOTES: MNXM3518

- - @@ -47989,6 +47684,7 @@ + @@ -48001,11 +47697,6 @@ - - -

NOTES: MNXM98606

- - @@ -48013,6 +47704,7 @@ + @@ -48025,11 +47717,6 @@ - - -

NOTES: MNXM98606

- - @@ -48037,6 +47724,7 @@ + @@ -48049,11 +47737,6 @@ - - -

NOTES: MNXM1781

- - @@ -48061,6 +47744,7 @@ + @@ -48073,11 +47757,6 @@ - - -

NOTES: MNXM323

- - @@ -48085,6 +47764,7 @@ + @@ -48097,11 +47777,6 @@ - - -

NOTES: MNXM1781

- - @@ -48109,6 +47784,7 @@ + @@ -48121,11 +47797,6 @@ - - -

NOTES: MNXM1630

- - @@ -48133,6 +47804,7 @@ + @@ -48145,11 +47817,6 @@ - - -

NOTES: MNXM1630

- - @@ -48157,6 +47824,7 @@ + @@ -48169,11 +47837,6 @@ - - -

NOTES: MNXM963

- - @@ -48181,6 +47844,7 @@ + @@ -48193,11 +47857,6 @@ - - -

NOTES: MNXM963

- - @@ -48205,6 +47864,7 @@ + @@ -48217,17 +47877,13 @@ - - -

NOTES: MNXM40494

- - + @@ -48240,17 +47896,13 @@ - - -

NOTES: MNXM40494

- - + @@ -48263,17 +47915,13 @@ - - -

NOTES: MNXM40494

- - + @@ -48286,17 +47934,13 @@ - - -

NOTES: MNXM61741

- - + @@ -48309,11 +47953,6 @@ - - -

NOTES: MNXM157

- - @@ -48321,6 +47960,7 @@ + @@ -48333,11 +47973,6 @@ - - -

NOTES: MNXM157

- - @@ -48345,6 +47980,7 @@ + @@ -48357,17 +47993,13 @@ - - -

NOTES: MNXM61741

- - + @@ -48380,11 +48012,6 @@ - - -

NOTES: MNXM3148

- - @@ -48392,6 +48019,7 @@ + @@ -48404,11 +48032,6 @@ - - -

NOTES: MNXM3148

- - @@ -48416,6 +48039,7 @@ + @@ -48428,11 +48052,6 @@ - - -

NOTES: MNXM92401

- - @@ -48440,6 +48059,7 @@ + @@ -48452,11 +48072,6 @@ - - -

NOTES: MNXM795

- - @@ -48464,6 +48079,7 @@ + @@ -48476,11 +48092,6 @@ - - -

NOTES: MNXM92401

- - @@ -48488,6 +48099,7 @@ + @@ -48500,11 +48112,6 @@ - - -

NOTES: MNXM161984

- - @@ -48512,6 +48119,7 @@ + @@ -48524,11 +48132,6 @@ - - -

NOTES: MNXM154

- - @@ -48536,6 +48139,7 @@ + @@ -48548,11 +48152,6 @@ - - -

NOTES: MNXM154

- - @@ -48560,6 +48159,7 @@ + @@ -48572,11 +48172,6 @@ - - -

NOTES: MNXM7576

- - @@ -48584,6 +48179,7 @@ + @@ -48596,11 +48192,6 @@ - - -

NOTES: MNXM7576

- - @@ -48608,6 +48199,7 @@ + @@ -48620,11 +48212,6 @@ - - -

NOTES: MNXM3850

- - @@ -48632,6 +48219,7 @@ + @@ -48644,11 +48232,6 @@ - - -

NOTES: MNXM3850

- - @@ -48656,6 +48239,7 @@ + @@ -48668,11 +48252,6 @@ - - -

NOTES: MNXM713

- - @@ -48680,6 +48259,7 @@ + @@ -48692,11 +48272,6 @@ - - -

NOTES: MNXM713

- - @@ -48704,6 +48279,7 @@ + @@ -48716,11 +48292,6 @@ - - -

NOTES: MNXM468

- - @@ -48728,6 +48299,7 @@ + @@ -48740,11 +48312,6 @@ - - -

NOTES: MNXM275

- - @@ -48752,6 +48319,7 @@ + @@ -48764,11 +48332,6 @@ - - -

NOTES: MNXM126

- - @@ -48776,6 +48339,7 @@ + @@ -48788,17 +48352,13 @@ - - -

NOTES: MNXM61647

- - + @@ -48811,17 +48371,13 @@ - - -

NOTES: MNXM61647

- - + @@ -48834,11 +48390,6 @@ - - -

NOTES: MNXM89588

- - @@ -48846,6 +48397,7 @@ + @@ -48858,11 +48410,6 @@ - - -

NOTES: MNXM138

- - @@ -48870,6 +48417,7 @@ + @@ -48882,11 +48430,6 @@ - - -

NOTES: MNXM379

- - @@ -48894,6 +48437,7 @@ + @@ -48906,11 +48450,6 @@ - - -

NOTES: MNXM113

- - @@ -48918,6 +48457,7 @@ + @@ -48930,11 +48470,6 @@ - - -

NOTES: MNXM491

- - @@ -48942,6 +48477,7 @@ + @@ -48954,11 +48490,6 @@ - - -

NOTES: MNXM160

- - @@ -48966,6 +48497,7 @@ + @@ -48978,11 +48510,6 @@ - - -

NOTES: MNXM80

- - @@ -48990,6 +48517,7 @@ + @@ -49002,11 +48530,6 @@ - - -

NOTES: MNXM73

- - @@ -49014,6 +48537,7 @@ + @@ -49026,11 +48550,6 @@ - - -

NOTES: MNXM427

- - @@ -49038,6 +48557,7 @@ + @@ -49050,11 +48570,6 @@ - - -

NOTES: MNXM187

- - @@ -49062,6 +48577,7 @@ + @@ -49074,11 +48590,6 @@ - - -

NOTES: MNXM325

- - @@ -49086,6 +48597,7 @@ + @@ -49098,11 +48610,6 @@ - - -

NOTES: MNXM721

- - @@ -49110,6 +48617,7 @@ + @@ -49122,11 +48630,6 @@ - - -

NOTES: MNXM11

- - @@ -49134,6 +48637,7 @@ + @@ -49146,11 +48650,6 @@ - - -

NOTES: MNXM229

- - @@ -49158,6 +48657,7 @@ + @@ -49170,11 +48670,6 @@ - - -

NOTES: MNXM323

- - @@ -49182,6 +48677,7 @@ + @@ -49194,11 +48690,6 @@ - - -

NOTES: MNXM14

- - @@ -49206,6 +48697,7 @@ + @@ -49218,11 +48710,6 @@ - - -

NOTES: MNXM2598

- - @@ -49230,6 +48717,7 @@ + @@ -49242,11 +48730,6 @@ - - -

NOTES: MNXM7028

- - @@ -49254,6 +48737,7 @@ + @@ -49266,11 +48750,6 @@ - - -

NOTES: MNXM31

- - @@ -49278,6 +48757,7 @@ + @@ -49290,11 +48770,6 @@ - - -

NOTES: MNXM533

- - @@ -49302,6 +48777,7 @@ + @@ -49314,11 +48790,6 @@ - - -

NOTES: MNXM2474

- - @@ -49326,6 +48797,7 @@ + @@ -49338,11 +48810,6 @@ - - -

NOTES: MNXM211

- - @@ -49350,6 +48817,7 @@ + @@ -49362,11 +48830,6 @@ - - -

NOTES: MNXM460

- - @@ -49374,6 +48837,7 @@ + @@ -49386,17 +48850,13 @@ - - -

NOTES: MNXM15786

- - + @@ -49409,17 +48869,13 @@ - - -

NOTES: MNXM15786

- - + @@ -49432,17 +48888,13 @@ - - -

NOTES: MNXM15783

- - + @@ -49455,17 +48907,13 @@ - - -

NOTES: MNXM15783

- - + @@ -49478,11 +48926,6 @@ - - -

NOTES: MNXM730

- - @@ -49490,6 +48933,7 @@ + @@ -49502,11 +48946,6 @@ - - -

NOTES: MNXM730

- - @@ -49514,6 +48953,7 @@ + @@ -49526,11 +48966,6 @@ - - -

NOTES: MNXM1024

- - @@ -49538,6 +48973,7 @@ + @@ -49550,11 +48986,6 @@ - - -

NOTES: MNXM1024

- - @@ -49562,6 +48993,7 @@ + @@ -49574,11 +49006,6 @@ - - -

NOTES: MNXM2246

- - @@ -49586,6 +49013,7 @@ + @@ -49598,11 +49026,6 @@ - - -

NOTES: MNXM345

- - @@ -49610,6 +49033,7 @@ + @@ -49622,11 +49046,6 @@ - - -

NOTES: MNXM691

- - @@ -49634,6 +49053,7 @@ + @@ -49646,11 +49066,6 @@ - - -

NOTES: MNXM708

- - @@ -49658,6 +49073,7 @@ + @@ -49670,11 +49086,6 @@ - - -

NOTES: MNXM597

- - @@ -49682,6 +49093,7 @@ + @@ -49694,11 +49106,6 @@ - - -

NOTES: MNXM1018

- - @@ -49706,6 +49113,7 @@ + diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index 9e3ef95f..cf5cfb04 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -20751,6 +20751,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73788 + - metanetx.chemical: MNXM40495 - !!omap - id: s_4035 - name: Ala-Gln @@ -20759,6 +20760,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73788 + - metanetx.chemical: MNXM40495 - !!omap - id: s_4036 - name: Ala-Gln @@ -20767,6 +20769,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73788 + - metanetx.chemical: MNXM40495 - !!omap - id: s_4037 - name: Ala-Glu @@ -20776,6 +20779,7 @@ - annotation: !!omap - chebi: CHEBI:61396 - kegg.compound: C20958 + - metanetx.chemical: MNXM4026 - !!omap - id: s_4038 - name: Ala-Glu @@ -20785,6 +20789,7 @@ - annotation: !!omap - chebi: CHEBI:61396 - kegg.compound: C20958 + - metanetx.chemical: MNXM4026 - !!omap - id: s_4039 - name: Ala-Glu @@ -20794,6 +20799,7 @@ - annotation: !!omap - chebi: CHEBI:61396 - kegg.compound: C20958 + - metanetx.chemical: MNXM4026 - !!omap - id: s_4040 - name: Ala-Thr @@ -20802,6 +20808,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73762 + - metanetx.chemical: MNXM40497 - !!omap - id: s_4041 - name: Ala-Thr @@ -20810,6 +20817,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73762 + - metanetx.chemical: MNXM40497 - !!omap - id: s_4042 - name: Ala-Thr @@ -20818,6 +20826,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73762 + - metanetx.chemical: MNXM40497 - !!omap - id: s_4043 - name: L-threonine @@ -20827,6 +20836,7 @@ - annotation: !!omap - chebi: CHEBI:16857 - kegg.compound: C00188 + - metanetx.chemical: MNXM142 - !!omap - id: s_4044 - name: thymidine 3'-monophosphate @@ -20835,6 +20845,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:77843 + - metanetx.chemical: MNXM87165 - !!omap - id: s_4045 - name: thymidine 3'-monophosphate @@ -20843,6 +20854,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:77843 + - metanetx.chemical: MNXM87165 - !!omap - id: s_4046 - name: thymidine 5'-monophosphate @@ -20851,6 +20863,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:15245 + - metanetx.chemical: MNXM87167 - !!omap - id: s_4047 - name: thymidine 5'-monophosphate @@ -20859,6 +20872,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:15245 + - metanetx.chemical: MNXM87167 - !!omap - id: s_4048 - name: glycerol 1-phosphate @@ -20868,6 +20882,7 @@ - annotation: !!omap - chebi: CHEBI:231935 - kegg.compound: C03189 + - metanetx.chemical: MNXM682 - !!omap - id: s_4049 - name: glycerol 1-phosphate @@ -20877,6 +20892,7 @@ - annotation: !!omap - chebi: CHEBI:231935 - kegg.compound: C03189 + - metanetx.chemical: MNXM682 - !!omap - id: s_4050 - name: Ala-His @@ -20885,6 +20901,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73771 + - metanetx.chemical: MNXM40496 - !!omap - id: s_4051 - name: Ala-His @@ -20893,6 +20910,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73771 + - metanetx.chemical: MNXM40496 - !!omap - id: s_4052 - name: Ala-His @@ -20901,6 +20919,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73771 + - metanetx.chemical: MNXM40496 - !!omap - id: s_4053 - name: Gly-Asn @@ -20909,6 +20928,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73888 + - metanetx.chemical: MNXM55268 - !!omap - id: s_4054 - name: Gly-Asn @@ -20917,6 +20937,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73888 + - metanetx.chemical: MNXM55268 - !!omap - id: s_4055 - name: Gly-Asn @@ -20925,6 +20946,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73888 + - metanetx.chemical: MNXM55268 - !!omap - id: s_4056 - name: Gly-Gln @@ -20933,6 +20955,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73898 + - metanetx.chemical: MNXM55276 - !!omap - id: s_4057 - name: Gly-Gln @@ -20941,6 +20964,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73898 + - metanetx.chemical: MNXM55276 - !!omap - id: s_4058 - name: Gly-Gln @@ -20949,6 +20973,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73898 + - metanetx.chemical: MNXM55276 - !!omap - id: s_4059 - name: Gly-Glu @@ -20957,6 +20982,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:73784 + - metanetx.chemical: MNXM55454 - !!omap - id: s_4060 - name: Gly-Glu @@ -20965,6 +20991,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:73784 + - metanetx.chemical: MNXM55454 - !!omap - id: s_4061 - name: Gly-Glu @@ -20973,6 +21000,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:73784 + - metanetx.chemical: MNXM55454 - !!omap - id: s_4062 - name: glycerol 2-phosphate(2-) @@ -20982,6 +21010,7 @@ - annotation: !!omap - chebi: CHEBI:58083 - kegg.compound: C02979 + - metanetx.chemical: MNXM2527 - !!omap - id: s_4063 - name: glycerol 2-phosphate(2-) @@ -20991,6 +21020,7 @@ - annotation: !!omap - chebi: CHEBI:58083 - kegg.compound: C02979 + - metanetx.chemical: MNXM2527 - !!omap - id: s_4064 - name: O-phospho-L-threonine @@ -21000,6 +21030,7 @@ - annotation: !!omap - chebi: CHEBI:58675 - kegg.compound: C12147 + - metanetx.chemical: MNXM1492 - !!omap - id: s_4065 - name: O-phospho-L-threonine @@ -21009,6 +21040,7 @@ - annotation: !!omap - chebi: CHEBI:58675 - kegg.compound: C12147 + - metanetx.chemical: MNXM1492 - !!omap - id: s_4066 - name: guanosine 2'-monophosphate @@ -21017,6 +21049,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:74604 + - metanetx.chemical: MNXM18285 - !!omap - id: s_4067 - name: guanosine 2'-monophosphate @@ -21025,6 +21058,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:74604 + - metanetx.chemical: MNXM18285 - !!omap - id: s_4068 - name: 3'-GMP @@ -21034,6 +21068,7 @@ - annotation: !!omap - chebi: CHEBI:60732 - kegg.compound: C06193 + - metanetx.chemical: MNXM2183 - !!omap - id: s_4069 - name: 3'-GMP @@ -21043,6 +21078,7 @@ - annotation: !!omap - chebi: CHEBI:60732 - kegg.compound: C06193 + - metanetx.chemical: MNXM2183 - !!omap - id: s_4070 - name: 2-phosphoglycolate @@ -21052,6 +21088,7 @@ - annotation: !!omap - chebi: CHEBI:58033 - kegg.compound: C00988 + - metanetx.chemical: MNXM2074 - !!omap - id: s_4071 - name: 2-phosphoglycolate @@ -21061,6 +21098,7 @@ - annotation: !!omap - chebi: CHEBI:58033 - kegg.compound: C00988 + - metanetx.chemical: MNXM2074 - !!omap - id: s_4072 - name: cysteamine S-phosphate @@ -21069,6 +21107,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:74631 + - metanetx.chemical: MNXM48297 - !!omap - id: s_4073 - name: cysteamine @@ -21078,6 +21117,7 @@ - annotation: !!omap - chebi: CHEBI:58029 - kegg.compound: C01678 + - metanetx.chemical: MNXM1226 - !!omap - id: s_4074 - name: cysteamine @@ -21087,6 +21127,7 @@ - annotation: !!omap - chebi: CHEBI:58029 - kegg.compound: C01678 + - metanetx.chemical: MNXM1226 - !!omap - id: s_4075 - name: cysteamine S-phosphate @@ -21095,6 +21136,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:74631 + - metanetx.chemical: MNXM48297 - !!omap - id: s_4076 - name: hypotaurine @@ -21104,6 +21146,7 @@ - annotation: !!omap - chebi: CHEBI:16668 - kegg.compound: C00519 + - metanetx.chemical: MNXM726 - !!omap - id: s_4077 - name: O-phosphonatooxy-D-serine(2-) @@ -21113,6 +21156,7 @@ - annotation: !!omap - chebi: CHEBI:58680 - kegg.compound: C02532 + - metanetx.chemical: MNXM4752 - !!omap - id: s_4078 - name: O-phosphonatooxy-D-serine(2-) @@ -21122,6 +21166,7 @@ - annotation: !!omap - chebi: CHEBI:58680 - kegg.compound: C02532 + - metanetx.chemical: MNXM4752 - !!omap - id: s_4079 - name: 2-aminobutanoate @@ -21130,6 +21175,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:35621 + - metanetx.chemical: MNXM15850 - !!omap - id: s_4080 - name: 2-aminobutanoate @@ -21138,6 +21184,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:35621 + - metanetx.chemical: MNXM15850 - !!omap - id: s_4081 - name: uridine 2'-phosphate @@ -21147,6 +21194,7 @@ - annotation: !!omap - chebi: CHEBI:77802 - kegg.compound: C03031 + - metanetx.chemical: MNXM13238 - !!omap - id: s_4082 - name: uridine 2'-phosphate @@ -21156,6 +21204,7 @@ - annotation: !!omap - chebi: CHEBI:77802 - kegg.compound: C03031 + - metanetx.chemical: MNXM13238 - !!omap - id: s_4083 - name: 3'-UMP @@ -21165,6 +21214,7 @@ - annotation: !!omap - chebi: CHEBI:60784 - kegg.compound: C01368 + - metanetx.chemical: MNXM2184 - !!omap - id: s_4084 - name: 3'-UMP @@ -21174,6 +21224,7 @@ - annotation: !!omap - chebi: CHEBI:60784 - kegg.compound: C01368 + - metanetx.chemical: MNXM2184 - !!omap - id: s_4085 - name: Gly-Met @@ -21182,6 +21233,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74393 + - metanetx.chemical: MNXM55287 - !!omap - id: s_4086 - name: Gly-Met @@ -21190,6 +21242,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74393 + - metanetx.chemical: MNXM55287 - !!omap - id: s_4087 - name: Gly-Met @@ -21198,6 +21251,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74393 + - metanetx.chemical: MNXM55287 - !!omap - id: s_4088 - name: N-phosphocreatine @@ -21206,6 +21260,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:58092 + - metanetx.chemical: MNXM819 - !!omap - id: s_4089 - name: creatinine @@ -21215,6 +21270,7 @@ - annotation: !!omap - chebi: CHEBI:16737 - kegg.compound: C00791 + - metanetx.chemical: MNXM1470 - !!omap - id: s_4090 - name: N-phosphocreatine @@ -21223,6 +21279,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:58092 + - metanetx.chemical: MNXM819 - !!omap - id: s_4091 - name: creatinine @@ -21232,6 +21289,7 @@ - annotation: !!omap - chebi: CHEBI:16737 - kegg.compound: C00791 + - metanetx.chemical: MNXM1470 - !!omap - id: s_4092 - name: N(omega)-phospho-L-arginine @@ -21241,6 +21299,7 @@ - annotation: !!omap - chebi: CHEBI:58477 - kegg.compound: C05945 + - metanetx.chemical: MNXM3663 - !!omap - id: s_4093 - name: N(omega)-phospho-L-arginine @@ -21250,6 +21309,7 @@ - annotation: !!omap - chebi: CHEBI:58477 - kegg.compound: C05945 + - metanetx.chemical: MNXM3663 - !!omap - id: s_4094 - name: 2',3'-cyclic GMP @@ -21259,6 +21319,7 @@ - annotation: !!omap - chebi: CHEBI:60837 - kegg.compound: C06194 + - metanetx.chemical: MNXM3149 - !!omap - id: s_4095 - name: 2',3'-cyclic GMP @@ -21268,6 +21329,7 @@ - annotation: !!omap - chebi: CHEBI:60837 - kegg.compound: C06194 + - metanetx.chemical: MNXM3149 - !!omap - id: s_4096 - name: O(4)-phospho-L-tyrosine @@ -21277,6 +21339,7 @@ - annotation: !!omap - chebi: CHEBI:62338 - kegg.compound: C06501 + - metanetx.chemical: MNXM3323 - !!omap - id: s_4097 - name: O(4)-phospho-L-tyrosine @@ -21286,6 +21349,7 @@ - annotation: !!omap - chebi: CHEBI:62338 - kegg.compound: C06501 + - metanetx.chemical: MNXM3323 - !!omap - id: s_4098 - name: triphosphate @@ -21295,6 +21359,7 @@ - annotation: !!omap - chebi: CHEBI:18036 - kegg.compound: C00536 + - metanetx.chemical: MNXM332 - !!omap - id: s_4099 - name: triphosphate @@ -21304,6 +21369,7 @@ - annotation: !!omap - chebi: CHEBI:18036 - kegg.compound: C00536 + - metanetx.chemical: MNXM332 - !!omap - id: s_4100 - name: cytidine 2'-phosphate @@ -21313,6 +21379,7 @@ - annotation: !!omap - chebi: CHEBI:77766 - kegg.compound: C03104 + - metanetx.chemical: MNXM11237 - !!omap - id: s_4101 - name: cytidine 2'-phosphate @@ -21322,6 +21389,7 @@ - annotation: !!omap - chebi: CHEBI:77766 - kegg.compound: C03104 + - metanetx.chemical: MNXM11237 - !!omap - id: s_4102 - name: 2',3'-cyclic UMP @@ -21331,6 +21399,7 @@ - annotation: !!omap - chebi: CHEBI:60873 - kegg.compound: C02355 + - metanetx.chemical: MNXM3150 - !!omap - id: s_4103 - name: 2',3'-cyclic UMP @@ -21340,6 +21409,7 @@ - annotation: !!omap - chebi: CHEBI:60873 - kegg.compound: C02355 + - metanetx.chemical: MNXM3150 - !!omap - id: s_4104 - name: 3-sulfino-L-alanine @@ -21349,6 +21419,7 @@ - annotation: !!omap - chebi: CHEBI:61085 - kegg.compound: C00606 + - metanetx.chemical: MNXM498 - !!omap - id: s_4105 - name: 3-sulfino-L-alanine @@ -21358,6 +21429,7 @@ - annotation: !!omap - chebi: CHEBI:61085 - kegg.compound: C00606 + - metanetx.chemical: MNXM498 - !!omap - id: s_4106 - name: 3'-AMP @@ -21367,6 +21439,7 @@ - annotation: !!omap - chebi: CHEBI:60880 - kegg.compound: C01367 + - metanetx.chemical: MNXM1985 - !!omap - id: s_4107 - name: 3'-AMP @@ -21376,6 +21449,7 @@ - annotation: !!omap - chebi: CHEBI:60880 - kegg.compound: C01367 + - metanetx.chemical: MNXM1985 - !!omap - id: s_4108 - name: 6-O-alpha-D-glucopyranosyl-D-fructofuranose @@ -21385,6 +21459,7 @@ - annotation: !!omap - chebi: CHEBI:18394 - kegg.compound: C01742 + - metanetx.chemical: MNXM3518 - !!omap - id: s_4109 - name: 6-O-alpha-D-glucopyranosyl-D-fructofuranose @@ -21394,6 +21469,7 @@ - annotation: !!omap - chebi: CHEBI:18394 - kegg.compound: C01742 + - metanetx.chemical: MNXM3518 - !!omap - id: s_4110 - name: N-acetyl-L-cysteine @@ -21403,6 +21479,7 @@ - annotation: !!omap - chebi: CHEBI:78236 - kegg.compound: C06809 + - metanetx.chemical: MNXM98606 - !!omap - id: s_4111 - name: N-acetyl-L-cysteine @@ -21412,6 +21489,7 @@ - annotation: !!omap - chebi: CHEBI:78236 - kegg.compound: C06809 + - metanetx.chemical: MNXM98606 - !!omap - id: s_4112 - name: tetrathionate @@ -21421,6 +21499,7 @@ - annotation: !!omap - chebi: CHEBI:15226 - kegg.compound: C02084 + - metanetx.chemical: MNXM1781 - !!omap - id: s_4113 - name: thiosulfate @@ -21430,6 +21509,7 @@ - annotation: !!omap - chebi: CHEBI:33542 - kegg.compound: C00320 + - metanetx.chemical: MNXM323 - !!omap - id: s_4114 - name: tetrathionate @@ -21439,6 +21519,7 @@ - annotation: !!omap - chebi: CHEBI:15226 - kegg.compound: C02084 + - metanetx.chemical: MNXM1781 - !!omap - id: s_4115 - name: 2-hydroxyethane-1-sulfonate @@ -21448,6 +21529,7 @@ - annotation: !!omap - chebi: CHEBI:61904 - kegg.compound: C05123 + - metanetx.chemical: MNXM1630 - !!omap - id: s_4116 - name: 2-hydroxyethane-1-sulfonate @@ -21457,6 +21539,7 @@ - annotation: !!omap - chebi: CHEBI:61904 - kegg.compound: C05123 + - metanetx.chemical: MNXM1630 - !!omap - id: s_4117 - name: 5-dehydro-D-gluconate @@ -21466,6 +21549,7 @@ - annotation: !!omap - chebi: CHEBI:58143 - kegg.compound: C01062 + - metanetx.chemical: MNXM963 - !!omap - id: s_4118 - name: 5-dehydro-D-gluconate @@ -21475,6 +21559,7 @@ - annotation: !!omap - chebi: CHEBI:58143 - kegg.compound: C01062 + - metanetx.chemical: MNXM963 - !!omap - id: s_4119 - name: Ala-Asp @@ -21483,6 +21568,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:74363 + - metanetx.chemical: MNXM40494 - !!omap - id: s_4120 - name: Ala-Asp @@ -21491,6 +21577,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:74363 + - metanetx.chemical: MNXM40494 - !!omap - id: s_4121 - name: Ala-Asp @@ -21499,6 +21586,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:74363 + - metanetx.chemical: MNXM40494 - !!omap - id: s_4122 - name: methyl alpha-D-glucopyranoside @@ -21507,6 +21595,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:320061 + - metanetx.chemical: MNXM61741 - !!omap - id: s_4123 - name: methanol @@ -21516,6 +21605,7 @@ - annotation: !!omap - chebi: CHEBI:17790 - kegg.compound: C00132 + - metanetx.chemical: MNXM157 - !!omap - id: s_4124 - name: methanol @@ -21525,6 +21615,7 @@ - annotation: !!omap - chebi: CHEBI:17790 - kegg.compound: C00132 + - metanetx.chemical: MNXM157 - !!omap - id: s_4125 - name: methyl alpha-D-glucopyranoside @@ -21533,6 +21624,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:320061 + - metanetx.chemical: MNXM61741 - !!omap - id: s_4126 - name: 2',3'-cyclic CMP @@ -21542,6 +21634,7 @@ - annotation: !!omap - chebi: CHEBI:60877 - kegg.compound: C02354 + - metanetx.chemical: MNXM3148 - !!omap - id: s_4127 - name: 2',3'-cyclic CMP @@ -21551,6 +21644,7 @@ - annotation: !!omap - chebi: CHEBI:60877 - kegg.compound: C02354 + - metanetx.chemical: MNXM3148 - !!omap - id: s_4128 - name: D-tagatose @@ -21560,6 +21654,7 @@ - annotation: !!omap - chebi: CHEBI:4249 - kegg.compound: C00795 + - metanetx.chemical: MNXM92401 - !!omap - id: s_4129 - name: D-tagatofuranose 6-phosphate @@ -21569,6 +21664,7 @@ - annotation: !!omap - chebi: CHEBI:58695 - kegg.compound: C01097 + - metanetx.chemical: MNXM795 - !!omap - id: s_4130 - name: D-tagatose @@ -21578,6 +21674,7 @@ - annotation: !!omap - chebi: CHEBI:4249 - kegg.compound: C00795 + - metanetx.chemical: MNXM92401 - !!omap - id: s_4131 - name: turanose @@ -21587,6 +21684,7 @@ - annotation: !!omap - chebi: CHEBI:32528 - kegg.compound: C19636 + - metanetx.chemical: MNXM161984 - !!omap - id: s_4132 - name: acetoacetate @@ -21596,6 +21694,7 @@ - annotation: !!omap - chebi: CHEBI:13705 - kegg.compound: C00164 + - metanetx.chemical: MNXM154 - !!omap - id: s_4133 - name: acetoacetate @@ -21605,6 +21704,7 @@ - annotation: !!omap - chebi: CHEBI:13705 - kegg.compound: C00164 + - metanetx.chemical: MNXM154 - !!omap - id: s_4134 - name: N(alpha)-acetyl-L-methionine @@ -21614,6 +21714,7 @@ - annotation: !!omap - chebi: CHEBI:132957 - kegg.compound: C02712 + - metanetx.chemical: MNXM7576 - !!omap - id: s_4135 - name: N(alpha)-acetyl-L-methionine @@ -21623,6 +21724,7 @@ - annotation: !!omap - chebi: CHEBI:132957 - kegg.compound: C02712 + - metanetx.chemical: MNXM7576 - !!omap - id: s_4136 - name: 3-oxalomalate(3-) @@ -21632,6 +21734,7 @@ - annotation: !!omap - chebi: CHEBI:15593 - kegg.compound: C01990 + - metanetx.chemical: MNXM3850 - !!omap - id: s_4137 - name: 3-oxalomalate(3-) @@ -21641,6 +21744,7 @@ - annotation: !!omap - chebi: CHEBI:15593 - kegg.compound: C01990 + - metanetx.chemical: MNXM3850 - !!omap - id: s_4138 - name: L-cysteate @@ -21650,6 +21754,7 @@ - annotation: !!omap - chebi: CHEBI:58090 - kegg.compound: C00506 + - metanetx.chemical: MNXM713 - !!omap - id: s_4139 - name: L-cysteate @@ -21659,6 +21764,7 @@ - annotation: !!omap - chebi: CHEBI:58090 - kegg.compound: C00506 + - metanetx.chemical: MNXM713 - !!omap - id: s_4140 - name: alpha-maltotriose @@ -21668,6 +21774,7 @@ - annotation: !!omap - chebi: CHEBI:61993 - kegg.compound: C01835 + - metanetx.chemical: MNXM468 - !!omap - id: s_4141 - name: 2-phospho-D-glyceric acid @@ -21677,6 +21784,7 @@ - annotation: !!omap - chebi: CHEBI:58289 - kegg.compound: C00631 + - metanetx.chemical: MNXM275 - !!omap - id: s_4142 - name: 3-phosphonato-D-glycerate(3-) @@ -21686,6 +21794,7 @@ - annotation: !!omap - chebi: CHEBI:58272 - kegg.compound: C00197 + - metanetx.chemical: MNXM126 - !!omap - id: s_4143 - name: Met-Ala @@ -21694,6 +21803,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73610 + - metanetx.chemical: MNXM61647 - !!omap - id: s_4144 - name: Met-Ala @@ -21702,6 +21812,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73610 + - metanetx.chemical: MNXM61647 - !!omap - id: s_4145 - name: D-glucose 1-phosphate @@ -21711,6 +21822,7 @@ - annotation: !!omap - chebi: CHEBI:57629 - kegg.compound: C00103 + - metanetx.chemical: MNXM89588 - !!omap - id: s_4146 - name: carbamoyl phosphate @@ -21720,6 +21832,7 @@ - annotation: !!omap - chebi: CHEBI:58228 - kegg.compound: C00169 + - metanetx.chemical: MNXM138 - !!omap - id: s_4147 - name: 3-phospho-serine @@ -21729,6 +21842,7 @@ - annotation: !!omap - chebi: CHEBI:57524 - kegg.compound: C01005 + - metanetx.chemical: MNXM379 - !!omap - id: s_4148 - name: GMP @@ -21738,6 +21852,7 @@ - annotation: !!omap - chebi: CHEBI:58115 - kegg.compound: C00144 + - metanetx.chemical: MNXM113 - !!omap - id: s_4149 - name: myo-inositol hexakisphosphate @@ -21747,6 +21862,7 @@ - annotation: !!omap - chebi: CHEBI:58130 - kegg.compound: C01204 + - metanetx.chemical: MNXM491 - !!omap - id: s_4150 - name: D-glucose 6-phosphate @@ -21756,6 +21872,7 @@ - annotation: !!omap - chebi: CHEBI:61548 - kegg.compound: C00092 + - metanetx.chemical: MNXM160 - !!omap - id: s_4151 - name: UMP @@ -21765,6 +21882,7 @@ - annotation: !!omap - chebi: CHEBI:57865 - kegg.compound: C00105 + - metanetx.chemical: MNXM80 - !!omap - id: s_4152 - name: phosphoenolpyruvate @@ -21774,6 +21892,7 @@ - annotation: !!omap - chebi: CHEBI:58702 - kegg.compound: C00074 + - metanetx.chemical: MNXM73 - !!omap - id: s_4153 - name: D-mannose 6-phosphate @@ -21783,6 +21902,7 @@ - annotation: !!omap - chebi: CHEBI:58735 - kegg.compound: C00275 + - metanetx.chemical: MNXM427 - !!omap - id: s_4154 - name: O-phosphoethanolamine @@ -21792,6 +21912,7 @@ - annotation: !!omap - chebi: CHEBI:58190 - kegg.compound: C00346 + - metanetx.chemical: MNXM187 - !!omap - id: s_4155 - name: 6-phospho-D-gluconate @@ -21801,6 +21922,7 @@ - annotation: !!omap - chebi: CHEBI:58759 - kegg.compound: C00345 + - metanetx.chemical: MNXM325 - !!omap - id: s_4156 - name: D-mannose 1-phosphate @@ -21810,6 +21932,7 @@ - annotation: !!omap - chebi: CHEBI:58409 - kegg.compound: C00636 + - metanetx.chemical: MNXM721 - !!omap - id: s_4157 - name: diphosphate @@ -21819,6 +21942,7 @@ - annotation: !!omap - chebi: CHEBI:33019 - kegg.compound: C00013 + - metanetx.chemical: MNXM11 - !!omap - id: s_4158 - name: choline phosphate @@ -21828,6 +21952,7 @@ - annotation: !!omap - chebi: CHEBI:295975 - kegg.compound: C00588 + - metanetx.chemical: MNXM229 - !!omap - id: s_4159 - name: thiosulfate @@ -21837,6 +21962,7 @@ - annotation: !!omap - chebi: CHEBI:33542 - kegg.compound: C00320 + - metanetx.chemical: MNXM323 - !!omap - id: s_4160 - name: AMP @@ -21846,6 +21972,7 @@ - annotation: !!omap - chebi: CHEBI:456215 - kegg.compound: C00020 + - metanetx.chemical: MNXM14 - !!omap - id: s_4161 - name: 2',3'-cyclic AMP @@ -21855,6 +21982,7 @@ - annotation: !!omap - chebi: CHEBI:60879 - kegg.compound: C02353 + - metanetx.chemical: MNXM2598 - !!omap - id: s_4162 - name: adenosine 2'-phosphate @@ -21864,6 +21992,7 @@ - annotation: !!omap - chebi: CHEBI:77740 - kegg.compound: C00946 + - metanetx.chemical: MNXM7028 - !!omap - id: s_4163 - name: CMP @@ -21873,6 +22002,7 @@ - annotation: !!omap - chebi: CHEBI:60377 - kegg.compound: C00055 + - metanetx.chemical: MNXM31 - !!omap - id: s_4164 - name: D-Glucosamine @@ -21882,6 +22012,7 @@ - annotation: !!omap - chebi: CHEBI:58723 - kegg.compound: C00329 + - metanetx.chemical: MNXM533 - !!omap - id: s_4165 - name: 2-deoxy-D-ribose @@ -21891,6 +22022,7 @@ - annotation: !!omap - chebi: CHEBI:28816 - kegg.compound: C08347 + - metanetx.chemical: MNXM2474 - !!omap - id: s_4166 - name: L-citrulline @@ -21900,6 +22032,7 @@ - annotation: !!omap - chebi: CHEBI:16349 - kegg.compound: C00327 + - metanetx.chemical: MNXM211 - !!omap - id: s_4167 - name: glycerone @@ -21909,6 +22042,7 @@ - annotation: !!omap - chebi: CHEBI:16016 - kegg.compound: C00184 + - metanetx.chemical: MNXM460 - !!omap - id: s_4168 - name: Ala-Leu @@ -21917,6 +22051,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73770 + - metanetx.chemical: MNXM15786 - !!omap - id: s_4169 - name: Ala-Leu @@ -21925,6 +22060,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73770 + - metanetx.chemical: MNXM15786 - !!omap - id: s_4170 - name: Ala-Gly @@ -21933,6 +22069,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73757 + - metanetx.chemical: MNXM15783 - !!omap - id: s_4171 - name: Ala-Gly @@ -21941,6 +22078,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73757 + - metanetx.chemical: MNXM15783 - !!omap - id: s_4172 - name: N-acetyl-L-glutamate @@ -21950,6 +22088,7 @@ - annotation: !!omap - chebi: CHEBI:44337 - kegg.compound: C00624 + - metanetx.chemical: MNXM730 - !!omap - id: s_4173 - name: N-acetyl-L-glutamate @@ -21959,6 +22098,7 @@ - annotation: !!omap - chebi: CHEBI:44337 - kegg.compound: C00624 + - metanetx.chemical: MNXM730 - !!omap - id: s_4174 - name: lipoamide @@ -21968,6 +22108,7 @@ - annotation: !!omap - chebi: CHEBI:17460 - kegg.compound: C00248 + - metanetx.chemical: MNXM1024 - !!omap - id: s_4175 - name: lipoamide @@ -21977,6 +22118,7 @@ - annotation: !!omap - chebi: CHEBI:17460 - kegg.compound: C00248 + - metanetx.chemical: MNXM1024 - !!omap - id: s_4176 - name: L-Methionine S-oxide @@ -21986,6 +22128,7 @@ - annotation: !!omap - chebi: CHEBI:17016 - kegg.compound: C02989 + - metanetx.chemical: MNXM2246 - !!omap - id: s_4177 - name: homogentisate @@ -21995,6 +22138,7 @@ - annotation: !!omap - chebi: CHEBI:16169 - kegg.compound: C00544 + - metanetx.chemical: MNXM345 - !!omap - id: s_4178 - name: 4-maleylacetoacetate @@ -22004,6 +22148,7 @@ - annotation: !!omap - chebi: CHEBI:17105 - kegg.compound: C01036 + - metanetx.chemical: MNXM691 - !!omap - id: s_4179 - name: 4-fumarylacetoacetate @@ -22013,6 +22158,7 @@ - annotation: !!omap - chebi: CHEBI:18034 - kegg.compound: C01061 + - metanetx.chemical: MNXM708 - !!omap - id: s_4180 - name: L-xylulose @@ -22022,6 +22168,7 @@ - annotation: !!omap - chebi: CHEBI:17140 - kegg.compound: C00310 + - metanetx.chemical: MNXM597 - !!omap - id: s_4181 - name: D-arabinitol @@ -22031,6 +22178,7 @@ - annotation: !!omap - chebi: CHEBI:18333 - kegg.compound: C01904 + - metanetx.chemical: MNXM1018 - reactions: - !!omap - id: r_0001 diff --git a/README.md b/README.md index 6b87d204..6e045459 100644 --- a/README.md +++ b/README.md @@ -10,7 +10,7 @@ This repository contains the current consensus genome-scale metabolic model of _ **GEM Category:** Species; **Utilisation:** predictive simulation, multi-omics integrative analysis, _in silico_ strain design, model template; **Field:** metabolic-network reconstruction; **Type of Model:** curated, reconstruction; **Model Source:** [Yeast 7.6](https://sourceforge.net/projects/yeast/); **Taxonomy:** _Saccharomyces cerevisiae_; **Metabolic System:** General Metabolism; **Condition:** aerobic, glucose-limited, defined media, maximization of growth. -* Last update: 2018-08-27 +* Last update: 2018-08-28 * Main Model Descriptors: From bb9ec38f912fb6b7cb7c357a416b98e4794a7026 Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Tue, 28 Aug 2018 16:24:54 +0200 Subject: [PATCH 16/27] feat-rxn.annot: metaNetX IDs --- .../modelCuration/addBiologRxnToGEM.m | 43 +- ModelFiles/xml/yeastGEM.xml | 417 ++++++++++++++++++ 2 files changed, 441 insertions(+), 19 deletions(-) diff --git a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m index 138a462e..e65527c2 100644 --- a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m +++ b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m @@ -6,7 +6,7 @@ % Biolog_newRxnMet.tsv. % % NOTE: changeGeneAssociation.m is a function from COBRA -% +% % Feiran Li 2018-08-25 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% @@ -30,10 +30,17 @@ newrxn.ID = rev{1}; newrxn.Rev = cellfun(@str2num, rev{2}); newrxn.GPR = rev{3}; -newrxn.rxnNames = rev{4}; -newrxn.rxnECNumbers = rev{5}; -newrxn.rxnKEGGID = rev{6}; -newrxn.rxnNotes = rev{7}; +newrxn.rxnNames = rev{4}; +newrxn.rxnECNumbers = rev{5}; +newrxn.rxnKEGGID = rev{6}; +newrxn.rxnNotes = rev{7}; +newrxn.rxnMetaNetXID = newrxn.ID; +for i = 1:length(newrxn.rxnMetaNetXID) + if ~startsWith(newrxn.rxnMetaNetXID{i},'MNXR') + newrxn.rxnMetaNetXID{i} = ''; + end +end +newrxn.rxnMetaNetXID = regexprep(newrxn.rxnMetaNetXID,'_cv',''); fclose(fid); % Change coefficients for reactants: @@ -108,12 +115,15 @@ EnergyResults = {}; MassChargeresults = {}; RedoxResults = {}; +if ~isfield(model,'rxnMetaNetXID') + model.rxnMetaNetXID = cell(size(model.rxns)); +end for i = 1:length(newrxn.ID) newID = getNewIndex(model.rxns); j = find(strcmp(matrix.rxnIDs,newrxn.ID{i})); Met = matrix.mets(j); Coef = transpose(matrix.metcoef(j)); - [model,dupIndex] = addReaction(model, ['r_' newID],... + [model,rxnIndex] = addReaction(model, ['r_' newID],... 'reactionName', newrxn.ID{i},... 'metaboliteList',Met,... 'stoichCoeffList',Coef,... @@ -122,10 +132,15 @@ 'checkDuplicate',1); [EnergyResults,RedoxResults] = CheckEnergyProduction(model,{['r_' newID]},EnergyResults,RedoxResults); [MassChargeresults] = CheckBalanceforSce(model,{['r_' newID]},MassChargeresults); - if isempty(dupIndex) - dupIndex = strcmp(model.rxns,['r_' newID]); + if isempty(rxnIndex) + rxnIndex = strcmp(model.rxns,['r_' newID]); end - model.rxnConfidenceScores(dupIndex) = 1; %reactions without gene but needed for modelling + % Add rxn annotation: + model.rxnNames{rxnIndex} = newrxn.rxnNames{i}; + model.rxnECNumbers(rxnIndex) = newrxn.rxnECNumbers(i); + model.rxnKEGGID(rxnIndex) = newrxn.rxnKEGGID(i); + model.rxnMetaNetXID(rxnIndex) = newrxn.rxnMetaNetXID(i); + model.rxnConfidenceScores(rxnIndex) = 1; %reactions without gene but needed for modelling end % Add gene standard name for new genes: @@ -147,16 +162,6 @@ model.proteins{i} = strcat('COBRAProtein',num2str(i)); end -% Add rxn annotation: -for i = 1:length(newrxn.ID) - [~,rxnID] = ismember(newrxn.ID(i),model.rxnNames); - if rxnID ~= 0 - model.rxnNames{rxnID} = newrxn.rxnNames{i}; - model.rxnECNumbers(rxnID) = newrxn.rxnECNumbers(i); - model.rxnKEGGID(rxnID) = newrxn.rxnKEGGID(i); - end -end - % Save model: cd .. saveYeastModel(model) diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index 8a9f9fbf..b39b0c69 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -177771,6 +177771,11 @@ + + + + + @@ -177799,6 +177804,7 @@ + @@ -177827,6 +177833,11 @@ + + + + + @@ -177856,6 +177867,7 @@ + @@ -177887,6 +177899,7 @@ + @@ -177945,6 +177958,7 @@ + @@ -177999,6 +178013,11 @@ + + + + + @@ -178029,6 +178048,7 @@ + @@ -178060,6 +178080,7 @@ + @@ -178116,6 +178137,7 @@ + @@ -178148,6 +178170,7 @@ + @@ -178182,6 +178205,7 @@ + @@ -178239,6 +178263,7 @@ + @@ -178267,6 +178292,11 @@ + + + + + @@ -178297,6 +178327,7 @@ + @@ -178325,6 +178356,11 @@ + + + + + @@ -178351,6 +178387,11 @@ + + + + + @@ -178380,6 +178421,7 @@ + @@ -178411,6 +178453,7 @@ + @@ -178494,6 +178537,7 @@ + @@ -178523,6 +178567,11 @@ + + + + + @@ -178549,6 +178598,11 @@ + + + + + @@ -178575,6 +178629,11 @@ + + + + + @@ -178604,6 +178663,7 @@ + @@ -178632,6 +178692,11 @@ + + + + + @@ -178661,6 +178726,7 @@ + @@ -178689,6 +178755,11 @@ + + + + + @@ -178719,6 +178790,7 @@ + @@ -178747,6 +178819,11 @@ + + + + + @@ -178777,6 +178854,7 @@ + @@ -178805,6 +178883,11 @@ + + + + + @@ -178832,6 +178915,7 @@ + @@ -178860,6 +178944,11 @@ + + + + + @@ -178886,6 +178975,11 @@ + + + + + @@ -178913,6 +179007,11 @@ + + + + + @@ -178942,6 +179041,7 @@ + @@ -178970,6 +179070,11 @@ + + + + + @@ -178999,6 +179104,7 @@ + @@ -179028,6 +179134,11 @@ + + + + + @@ -179057,6 +179168,7 @@ + @@ -179085,6 +179197,11 @@ + + + + + @@ -179114,6 +179231,7 @@ + @@ -179142,6 +179260,11 @@ + + + + + @@ -179171,6 +179294,7 @@ + @@ -179199,6 +179323,11 @@ + + + + + @@ -179223,6 +179352,11 @@ + + + + + @@ -179252,6 +179386,7 @@ + @@ -179305,6 +179440,11 @@ + + + + + @@ -179333,6 +179473,7 @@ + @@ -179366,6 +179507,7 @@ + @@ -179394,6 +179536,11 @@ + + + + + @@ -179420,6 +179567,11 @@ + + + + + @@ -179449,6 +179601,7 @@ + @@ -179533,6 +179686,7 @@ + @@ -179617,6 +179771,11 @@ + + + + + @@ -179647,6 +179806,7 @@ + @@ -179675,6 +179835,11 @@ + + + + + @@ -179704,6 +179869,7 @@ + @@ -179736,6 +179902,7 @@ + @@ -179767,6 +179934,7 @@ + @@ -179799,6 +179967,7 @@ + @@ -179830,6 +179999,7 @@ + @@ -179861,6 +180031,7 @@ + @@ -179892,6 +180063,7 @@ + @@ -179923,6 +180095,7 @@ + @@ -179954,6 +180127,7 @@ + @@ -179985,6 +180159,7 @@ + @@ -180013,6 +180188,11 @@ + + + + + @@ -180042,6 +180222,7 @@ + @@ -180070,6 +180251,11 @@ + + + + + @@ -180096,6 +180282,11 @@ + + + + + @@ -180122,6 +180313,11 @@ + + + + + @@ -180148,6 +180344,11 @@ + + + + + @@ -180174,6 +180375,11 @@ + + + + + @@ -180200,6 +180406,11 @@ + + + + + @@ -180226,6 +180437,11 @@ + + + + + @@ -180252,6 +180468,11 @@ + + + + + @@ -180278,6 +180499,11 @@ + + + + + @@ -180304,6 +180530,11 @@ + + + + + @@ -180330,6 +180561,11 @@ + + + + + @@ -180359,6 +180595,7 @@ + @@ -180557,6 +180794,7 @@ + @@ -180654,6 +180892,11 @@ + + + + + @@ -180678,6 +180921,11 @@ + + + + + @@ -180704,6 +180952,11 @@ + + + + + @@ -180730,6 +180983,11 @@ + + + + + @@ -180754,6 +181012,11 @@ + + + + + @@ -180830,6 +181093,11 @@ + + + + + @@ -180856,6 +181124,11 @@ + + + + + @@ -180882,6 +181155,11 @@ + + + + + @@ -180906,6 +181184,11 @@ + + + + + @@ -180930,6 +181213,11 @@ + + + + + @@ -180954,6 +181242,11 @@ + + + + + @@ -180980,6 +181273,11 @@ + + + + + @@ -181004,6 +181302,11 @@ + + + + + @@ -181030,6 +181333,11 @@ + + + + + @@ -181056,6 +181364,11 @@ + + + + + @@ -181082,6 +181395,11 @@ + + + + + @@ -181108,6 +181426,11 @@ + + + + + @@ -181132,6 +181455,11 @@ + + + + + @@ -181156,6 +181484,11 @@ + + + + + @@ -181182,6 +181515,11 @@ + + + + + @@ -181206,6 +181544,11 @@ + + + + + @@ -181232,6 +181575,11 @@ + + + + + @@ -181258,6 +181606,11 @@ + + + + + @@ -181306,6 +181659,11 @@ + + + + + @@ -181332,6 +181690,11 @@ + + + + + @@ -181408,6 +181771,11 @@ + + + + + @@ -181434,6 +181802,11 @@ + + + + + @@ -181508,6 +181881,11 @@ + + + + + @@ -181534,6 +181912,11 @@ + + + + + @@ -181584,6 +181967,11 @@ + + + + + @@ -181636,6 +182024,11 @@ + + + + + @@ -181662,6 +182055,11 @@ + + + + + @@ -181693,6 +182091,7 @@ + @@ -181732,6 +182131,7 @@ + @@ -181764,6 +182164,7 @@ + @@ -181796,6 +182197,7 @@ + @@ -181826,6 +182228,7 @@ + @@ -181859,6 +182262,7 @@ + @@ -181892,6 +182296,7 @@ + @@ -181952,6 +182357,7 @@ + @@ -181981,6 +182387,11 @@ + + + + + @@ -182005,6 +182416,11 @@ + + + + + @@ -182029,6 +182445,7 @@ + From e9ee2164f7662bbe733d7e9ddf2dc9d43cba913d Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Wed, 29 Aug 2018 12:07:41 +0200 Subject: [PATCH 17/27] fix-rxn.annot: complying rxnNames * Transport rxns cannot have as name "exchange rxn", as it is reserved * Transport and exchange rxns should have their names following convention, e.g. "met_name transport" or "met_name exchange". * Greek letters have to be spelled out (i.e. "alpha") --- ComplementaryData/modelCuration/Biolog_newRxnProp.tsv | 8 ++++---- ModelFiles/xml/yeastGEM.xml | 8 ++++---- ModelFiles/yml/yeastGEM.yml | 8 ++++---- README.md | 2 +- 4 files changed, 13 insertions(+), 13 deletions(-) diff --git a/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv b/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv index 0128f240..263064b2 100644 --- a/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv +++ b/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv @@ -1,5 +1,5 @@ rxnID rev GPR rxn_name_seed EC rxnID_kegg Source;reason -MNXR98598 1 Exchange rxns for glyc bigg:EX_glyc2p_e;glycerol 2-phosphate(2-)_P Source +MNXR98598 1 glycerol 2-phosphate(2-) transport bigg:EX_glyc2p_e;glycerol 2-phosphate(2-)_P Source MNXR99852 0 Glycerol-2-phosphate phosphohydrolase 3.1.3.19 R01043 rhea:13105;glycerol 2-phosphate(2-)_P Source MNXR136678 1 L-Threonine phosphate transport in via proton symport seed:rxn11407;O-phospho-L-threonine_P Source MNXR103332 0 acid phosphatase / phosphotransferase 3.1.3.- rhea:30579;O-phospho-L-threonine_P Source @@ -36,7 +36,7 @@ MNXR123155 0 3-Sulfino-L-alanine 4-carboxy-lyase 3.13.1.- R00863 rhea:28278;3-s MNXR137086 1 3-Sulfino-L-alanine transport via proton antiport seed:rxn12567;3-sulfino-L-alanine_S Source MNXR94935 0 adenosine 3'-phosphate phosphohydrolase 3.1.3.6 R01562 rhea:27898;3'-AMP_P Source MNXR94857 1 3AMP transport via diffusion (extracellular to periplasm) seed:rxn07973;3'-AMP_P Source -MNXR130717 0 α-glucosidase 3.2.1.20 sabiork:11700;6-O-alpha-D-glucopyranosyl-D-fructofuranose_C Source +MNXR130717 0 alpha-glucosidase 3.2.1.20 sabiork:11700;6-O-alpha-D-glucopyranosyl-D-fructofuranose_C Source MNXR102339 1 Palatinose transport in via proton symport seed:rxn05629;6-O-alpha-D-glucopyranosyl-D-fructofuranose_C Source MNXR103637 1 Amino-Acid N-Acetyltransferase bigg:RE2223M;N-acetyl-L-cysteine_S Source MNXR137052 1 Acetylcysteine transport via proton symport seed:rxn12528;N-acetyl-L-cysteine_S Source @@ -111,7 +111,7 @@ Met-Ala transport via proton symport (cytosol to vacuole) 1 Met-Ala transport v MNXR103245 1 O-Phospho-L-serine transport in via proton symport seed:rxn05640;3-phospho-serine_P Source MNXR100385 1 GMP transport via proton symport seed:rxn05471;GMP_P Source MNXR101585 1 myo-inositol phosphate transport via diffusion (extracellular to periplasm) seed:rxn08925;myo-inositol hexakisphosphate_P Source -MNXR98531 1 Exchange rxns for g6p bigg:EX_g6p_e;D-glucose 6-phosphate_P Source +MNXR98531 1 D-glucose 6-phosphate transport bigg:EX_g6p_e;D-glucose 6-phosphate_P Source MNXR105127 1 UMP transport rhea:27926;UMP_P Source MNXR102493 1 Phosphoenolpyruvate transport in via proton symport seed:rxn05630;phosphoenolpyruvate_P Source MNXR101385 1 Mannose 6-phosphate transport via diffusion (extracellular to periplasm) seed:rxn08880;D-mannose 6-phosphate_P Source @@ -152,5 +152,5 @@ MNXR105265 1 Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming) 1.1.1.10 R0190 arabinose reductase (D-arabinose) 0 arabinose reductase (D-arabinose) NA;D-arabinose_C Source MNXR95188 0 D-arabinitol:NAT 4-oxidoreductase 1.1.1.11 R05604 rhea:17921;D-arabinose_C Source MNXR95208 1 Acetoacetate transport via diffusion rhea:29751;acetoacetate_C Source -MNXR98748 1 Exchange rxns for meoh bigg:EX_meoh_e;methyl alpha-D-glucopyranoside_C Source +MNXR98748 1 methanol exchange bigg:EX_meoh_e;methyl alpha-D-glucopyranoside_C Source MNXR118733 0 alkaline phosphatase 3.1.3.- rhea:37343;adenosine 2'-phosphate_P Source diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index b39b0c69..7add2211 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -177762,7 +177762,7 @@ - +

Confidence Level: 1

@@ -178903,7 +178903,7 @@ - +

Confidence Level: 1

@@ -181175,7 +181175,7 @@ - +

Confidence Level: 1

@@ -182407,7 +182407,7 @@ - +

Confidence Level: 1

diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index cf5cfb04..465f7cb2 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -79248,7 +79248,7 @@ - confidence_score: 0 - !!omap - id: r_4341 - - name: Exchange rxns for glyc + - name: glycerol 2-phosphate(2-) transport - metabolites: !!omap - s_4062: 1 - s_4063: -1 @@ -79697,7 +79697,7 @@ - confidence_score: 1 - !!omap - id: r_4378 - - name: α-glucosidase + - name: alpha-glucosidase - metabolites: !!omap - s_0553: 1 - s_0563: 1 @@ -80564,7 +80564,7 @@ - confidence_score: 1 - !!omap - id: r_4453 - - name: Exchange rxns for g6p + - name: D-glucose 6-phosphate transport - metabolites: !!omap - s_0568: 1 - s_4150: -1 @@ -81019,7 +81019,7 @@ - confidence_score: 1 - !!omap - id: r_4494 - - name: Exchange rxns for meoh + - name: methanol exchange - metabolites: !!omap - s_4124: -1 - lower_bound: -1000 diff --git a/README.md b/README.md index 6e045459..0d31a7a0 100644 --- a/README.md +++ b/README.md @@ -10,7 +10,7 @@ This repository contains the current consensus genome-scale metabolic model of _ **GEM Category:** Species; **Utilisation:** predictive simulation, multi-omics integrative analysis, _in silico_ strain design, model template; **Field:** metabolic-network reconstruction; **Type of Model:** curated, reconstruction; **Model Source:** [Yeast 7.6](https://sourceforge.net/projects/yeast/); **Taxonomy:** _Saccharomyces cerevisiae_; **Metabolic System:** General Metabolism; **Condition:** aerobic, glucose-limited, defined media, maximization of growth. -* Last update: 2018-08-28 +* Last update: 2018-08-29 * Main Model Descriptors: From a2691971d7c83087ff19d4ae919e7c915bc3179c Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Wed, 29 Aug 2018 12:37:15 +0200 Subject: [PATCH 18/27] fix-rxn.annot: typo in rxnNames --- .../modelCuration/Biolog_newRxnMatrix.tsv | 40 +++++++++---------- .../modelCuration/Biolog_newRxnProp.tsv | 10 ++--- ModelFiles/xml/yeastGEM.xml | 10 ++--- ModelFiles/yml/yeastGEM.yml | 10 ++--- 4 files changed, 35 insertions(+), 35 deletions(-) diff --git a/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv b/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv index ae6f6b32..44e39b4e 100644 --- a/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv +++ b/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv @@ -23,10 +23,10 @@ MNXR101011 1 Ala-Glu reactant vacuole MNXR101011 1 H2O reactant vacuole MNXR101011 1 L-glutamate product vacuole MNXR101011 1 L-alanine product vacuole -Ala-Thr transport via proton symport (excelluar to cytosol) 1 Ala-Thr reactant extracellular -Ala-Thr transport via proton symport (excelluar to cytosol) 1 H+ reactant extracellular -Ala-Thr transport via proton symport (excelluar to cytosol) 1 H+ product cytoplasm -Ala-Thr transport via proton symport (excelluar to cytosol) 1 Ala-Thr product cytoplasm +Ala-Thr transport via proton symport (extracellular to cytosol) 1 Ala-Thr reactant extracellular +Ala-Thr transport via proton symport (extracellular to cytosol) 1 H+ reactant extracellular +Ala-Thr transport via proton symport (extracellular to cytosol) 1 H+ product cytoplasm +Ala-Thr transport via proton symport (extracellular to cytosol) 1 Ala-Thr product cytoplasm Ala-Thr transport via proton symport (cytosol to vacuole) 1 H+ reactant cytoplasm Ala-Thr transport via proton symport (cytosol to vacuole) 1 Ala-Thr reactant cytoplasm Ala-Thr transport via proton symport (cytosol to vacuole) 1 H+ product vacuole @@ -67,10 +67,10 @@ MNXR123347 1 Ala-His reactant vacuole MNXR123347 1 H2O reactant vacuole MNXR123347 1 L-histidine product vacuole MNXR123347 1 L-alanine product vacuole -Gly-Asn transport via proton symport (excelluar to cytosol) 1 Gly-Asn reactant extracellular -Gly-Asn transport via proton symport (excelluar to cytosol) 1 H+ reactant extracellular -Gly-Asn transport via proton symport (excelluar to cytosol) 1 H+ product cytoplasm -Gly-Asn transport via proton symport (excelluar to cytosol) 1 Gly-Asn product cytoplasm +Gly-Asn transport via proton symport (extracellular to cytosol) 1 Gly-Asn reactant extracellular +Gly-Asn transport via proton symport (extracellular to cytosol) 1 H+ reactant extracellular +Gly-Asn transport via proton symport (extracellular to cytosol) 1 H+ product cytoplasm +Gly-Asn transport via proton symport (extracellular to cytosol) 1 Gly-Asn product cytoplasm Gly-Asn transport via proton symport (cytosol to vacuole) 1 H+ reactant cytoplasm Gly-Asn transport via proton symport (cytosol to vacuole) 1 Gly-Asn reactant cytoplasm Gly-Asn transport via proton symport (cytosol to vacuole) 1 H+ product vacuole @@ -91,10 +91,10 @@ MNXR123351 1 Gly-Gln reactant vacuole MNXR123351 1 H2O reactant vacuole MNXR123351 1 L-glycine product vacuole MNXR123351 1 L-glutamine product vacuole -Gly-Glu transport via proton symport (excelluar to cytosol) 1 Gly-Glu reactant extracellular -Gly-Glu transport via proton symport (excelluar to cytosol) 1 H+ reactant extracellular -Gly-Glu transport via proton symport (excelluar to cytosol) 1 H+ product cytoplasm -Gly-Glu transport via proton symport (excelluar to cytosol) 1 Gly-Glu product cytoplasm +Gly-Glu transport via proton symport (extracellular to cytosol) 1 Gly-Glu reactant extracellular +Gly-Glu transport via proton symport (extracellular to cytosol) 1 H+ reactant extracellular +Gly-Glu transport via proton symport (extracellular to cytosol) 1 H+ product cytoplasm +Gly-Glu transport via proton symport (extracellular to cytosol) 1 Gly-Glu product cytoplasm Gly-Glu transport via proton symport (cytosol to vacuole) 1 H+ reactant cytoplasm Gly-Glu transport via proton symport (cytosol to vacuole) 1 Gly-Glu reactant cytoplasm Gly-Glu transport via proton symport (cytosol to vacuole) 1 H+ product vacuole @@ -412,10 +412,10 @@ MNXR94973 1 H+ reactant extracellular MNXR94973 1 3-phosphonato-D-glycerate(3-) reactant extracellular MNXR94973 1 3-phosphonato-D-glycerate(3-) product cytoplasm MNXR94973 1 H+ product cytoplasm -Met-Ala transport via proton symport (excelluar to cytosol) 1 Met-Ala reactant extracellular -Met-Ala transport via proton symport (excelluar to cytosol) 1 H+ reactant extracellular -Met-Ala transport via proton symport (excelluar to cytosol) 1 H+ product cytoplasm -Met-Ala transport via proton symport (excelluar to cytosol) 1 Met-Ala product cytoplasm +Met-Ala transport via proton symport (extracellular to cytosol) 1 Met-Ala reactant extracellular +Met-Ala transport via proton symport (extracellular to cytosol) 1 H+ reactant extracellular +Met-Ala transport via proton symport (extracellular to cytosol) 1 H+ product cytoplasm +Met-Ala transport via proton symport (extracellular to cytosol) 1 Met-Ala product cytoplasm Met-Ala transport via proton symport (cytosol to vacuole) 1 H+ reactant cytoplasm Met-Ala transport via proton symport (cytosol to vacuole) 1 Met-Ala reactant cytoplasm Met-Ala transport via proton symport (cytosol to vacuole) 1 H+ product vacuole @@ -488,10 +488,10 @@ MNXR96737 1 H+ product cytoplasm MNXR96737 1 L-citrulline product cytoplasm MNXR97367 1 glycerone reactant extracellular MNXR97367 1 glycerone product cytoplasm -Ala-Leu transport via proton symport (excelluar to cytosol) 1 Ala-Leu reactant extracellular -Ala-Leu transport via proton symport (excelluar to cytosol) 1 H+ reactant extracellular -Ala-Leu transport via proton symport (excelluar to cytosol) 1 H+ product cytoplasm -Ala-Leu transport via proton symport (excelluar to cytosol) 1 Ala-Leu product cytoplasm +Ala-Leu transport via proton symport (extracellular to cytosol) 1 Ala-Leu reactant extracellular +Ala-Leu transport via proton symport (extracellular to cytosol) 1 H+ reactant extracellular +Ala-Leu transport via proton symport (extracellular to cytosol) 1 H+ product cytoplasm +Ala-Leu transport via proton symport (extracellular to cytosol) 1 Ala-Leu product cytoplasm Ala-Leu transport via proton symport (cytosol to vacuole) 1 H+ reactant cytoplasm Ala-Leu transport via proton symport (cytosol to vacuole) 1 Ala-Leu reactant cytoplasm Ala-Leu transport via proton symport (cytosol to vacuole) 1 H+ product vacuole diff --git a/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv b/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv index 263064b2..66ec1099 100644 --- a/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv +++ b/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv @@ -60,9 +60,9 @@ MNXR137087 1 Ala-Gln transport via proton symport seed:rxn12568;Ala-Gln_N Sou MNXR101006_cv 1 L-alanyl-L-glutamate transport in via proton symport rhea:35131;Ala-Glu_N Source MNXR101619 0 Maltodextrin glucosidase (maltotriose) 3.2.1.20 seed:rxn05746;alpha-maltotriose_C Source Ala-Thr transport via proton symport (cytosol to vacuole) 1 Ala-Thr transport via proton symport NA;Ala-Thr_N Source -Ala-Thr transport via proton symport (excelluar to cytosol) 1 Ala-Thr transport via proton symport NA;Ala-Thr_N Source +Ala-Thr transport via proton symport (extracellular to cytosol) 1 Ala-Thr transport via proton symport (extracellular to cytosol) NA;Ala-Thr_N Source MNXR103069 0 ( YHR201C or YDR452W ) Triphosphate phosphohydrolase 3.6.1.25 R00138 rhea:14157;triphosphate_P Source -Gly-Asn transport via proton symport (excelluar to cytosol) 1 Gly-Asn transport via proton symport NA;Gly-Asn_N Source +Gly-Asn transport via proton symport (extracellular to cytosol) 1 Gly-Asn transport via proton symport (extracellular to cytosol) NA;Gly-Asn_N Source glycerol 1-phosphate transport 1 glycerol 1-phosphate transport NA;glycerol 1-phosphate_P Source MNXR103244 1 D-O-Phosphoserine transport in/out via proton symport seed:rxn05639;O-phosphonatooxy-D-serine(2-)_P Source MNXR103265 1 D-O-Phosphoserine phosphohydrolase 3.1.3.3 R02853 rhea:24873;O-phosphonatooxy-D-serine(2-)_P Source @@ -95,7 +95,7 @@ thymidine 3'-monophosphate transport 1 thymidine 3-monophosphate transport NA thymidine 5'-monophosphate transport 1 thymidine 5-monophosphate transport NA;thymidine 5'-monophosphate_P Source RHEA:11477 0 ( YIL053W or YER062C ) glycerol-1-phosphate phosphohydrolase R08658 NA;glycerol 1-phosphate_P Source nucleotide-specific phosphatase (thymidine 5'-monophosphate) 0 nucleotide-specific phosphatase (thymidine 5'-monophosphate) NA;thymidine 5'-monophosphate_P Source -Gly-Glu transport via proton symport (excelluar to cytosol) 1 Gly-Glu transport via proton symport (excelluar to cytosol) NA;Gly-Glu_N Source +Gly-Glu transport via proton symport (extracellular to cytosol) 1 Gly-Glu transport via proton symport (extracellular to cytosol) NA;Gly-Glu_N Source Gly-Glu transport via proton symport (cytosol to vacuole) 1 Gly-Glu transport via proton symport (cytosol to vacuole) NA;Gly-Glu_N Source MNXR123352 0 cytosol nonspecific dipeptidase 3.4.13.18 rhea:36463;Gly-Glu_N Source L-methionine transport, vacuoluar 1 L-methionine transport, vacuoluar NA;L-methionine_N Source @@ -106,7 +106,7 @@ MNXR94824 1 D-Glycerate 2-phosphate transport in/out via proton symport seed: MNXR94973 1 3-Phospho-D-glycerate transport in/out via proton symport seed:rxn05479;3-phosphonato-D-glycerate(3-)_P Source MNXR99849 1 D-glucose 1-phosphate transport via diffusion seed:rxn08545;D-glucose 1-phosphate_P Source MNXR96488 1 carbamoyl phosphate nuclear transport via diffusion seed:rxn09823;carbamoyl phosphate_P Source -Met-Ala transport via proton symport (excelluar to cytosol) 1 Met-Ala transport via proton symport (excelluar to cytosol) NA;Met-Ala_N Source +Met-Ala transport via proton symport (extracellular to cytosol) 1 Met-Ala transport via proton symport (extracellular to cytosol) NA;Met-Ala_N Source Met-Ala transport via proton symport (cytosol to vacuole) 1 Met-Ala transport via proton symport (cytosol to vacuole) NA;Met-Ala_N Source MNXR103245 1 O-Phospho-L-serine transport in via proton symport seed:rxn05640;3-phospho-serine_P Source MNXR100385 1 GMP transport via proton symport seed:rxn05471;GMP_P Source @@ -129,7 +129,7 @@ MNXR100035 1 D-glucosamine transport via diffusion (extracellular to periplasm) 2-deoxy-D-ribose transport 1 2-deoxy-D-ribose transport NA;2-deoxy-D-ribose_C Source MNXR96737 1 L-Citrulline transport in via proton symport seed:rxn05674;L-citrulline_N Source MNXR97367 1 Dihydroxyacetone transport via facilitated diffusion seed:rxn05532;glycerone_C Source -Ala-Leu transport via proton symport (excelluar to cytosol) 1 Ala-Leu transport via proton symport (excelluar to cytosol) NA;Ala-Leu_N Source +Ala-Leu transport via proton symport (extracellular to cytosol) 1 Ala-Leu transport via proton symport (extracellular to cytosol) NA;Ala-Leu_N Source Ala-Leu transport via proton symport (cytosol to vacuole) 1 Ala-Leu transport via proton symport (cytosol to vacuole) NA;Ala-Leu_N Source MNXR137133 1 L-alanylglycine transport via proton antiport seed:rxn12625;Ala-Gly_N Source MNXR137133_cv 1 L-alanylglycine transport via proton antiport seed:rxn12625;Ala-Gly_N Source diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index 7add2211..ff1dae26 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -179647,7 +179647,7 @@ - +

Confidence Level: 1

@@ -179712,7 +179712,7 @@ - +

Confidence Level: 1

@@ -180730,7 +180730,7 @@ - +

Confidence Level: 1

@@ -181032,7 +181032,7 @@ - +

Confidence Level: 1

@@ -181710,7 +181710,7 @@ - +

Confidence Level: 1

diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index 465f7cb2..f8c5e46b 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -79982,7 +79982,7 @@ - confidence_score: 1 - !!omap - id: r_4402 - - name: Ala-Thr transport via proton symport + - name: Ala-Thr transport via proton symport (extracellular to cytosol) - metabolites: !!omap - s_0794: 1 - s_0796: -1 @@ -80008,7 +80008,7 @@ - confidence_score: 1 - !!omap - id: r_4404 - - name: Gly-Asn transport via proton symport + - name: Gly-Asn transport via proton symport (extracellular to cytosol) - metabolites: !!omap - s_0794: 1 - s_0796: -1 @@ -80401,7 +80401,7 @@ - confidence_score: 1 - !!omap - id: r_4437 - - name: Gly-Glu transport via proton symport (excelluar to cytosol) + - name: Gly-Glu transport via proton symport (extracellular to cytosol) - metabolites: !!omap - s_0794: 1 - s_0796: -1 @@ -80511,7 +80511,7 @@ - confidence_score: 1 - !!omap - id: r_4448 - - name: Met-Ala transport via proton symport (excelluar to cytosol) + - name: Met-Ala transport via proton symport (extracellular to cytosol) - metabolites: !!omap - s_0794: 1 - s_0796: -1 @@ -80744,7 +80744,7 @@ - confidence_score: 1 - !!omap - id: r_4471 - - name: Ala-Leu transport via proton symport (excelluar to cytosol) + - name: Ala-Leu transport via proton symport (extracellular to cytosol) - metabolites: !!omap - s_0794: 1 - s_0796: -1 From 113eb4a6f1f1fa49c9bc2b5cc551952fb76e7080 Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Wed, 29 Aug 2018 12:52:00 +0200 Subject: [PATCH 19/27] fix-rxn.annot: cysteamine exchange --- ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv | 2 +- ComplementaryData/modelCuration/Biolog_newRxnProp.tsv | 2 +- ModelFiles/xml/yeastGEM.xml | 2 +- ModelFiles/yml/yeastGEM.yml | 2 +- 4 files changed, 4 insertions(+), 4 deletions(-) diff --git a/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv b/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv index 44e39b4e..f70f9f09 100644 --- a/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv +++ b/ComplementaryData/modelCuration/Biolog_newRxnMatrix.tsv @@ -147,7 +147,7 @@ MNXR118734 1 cysteamine product cytoplasm MNXR137130 1 H+ reactant extracellular MNXR137130 1 cysteamine reactant extracellular MNXR137130 1 cysteamine product cytoplasm -Exchange reaction, cysteamine 1 cysteamine reactant extracellular +cysteamine exchange 1 cysteamine reactant extracellular MNXR137130 1 H+ product cytoplasm MNXR118734 1 phosphate product cytoplasm cysteamine S-phosphate transport via proton symport 1 cysteamine S-phosphate reactant extracellular diff --git a/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv b/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv index 66ec1099..13597128 100644 --- a/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv +++ b/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv @@ -100,7 +100,7 @@ Gly-Glu transport via proton symport (cytosol to vacuole) 1 Gly-Glu transport v MNXR123352 0 cytosol nonspecific dipeptidase 3.4.13.18 rhea:36463;Gly-Glu_N Source L-methionine transport, vacuoluar 1 L-methionine transport, vacuoluar NA;L-methionine_N Source L-threonine transport, vacuoluar 1 L-threonine transport, vacuoluar NA;L-threonine_N Source -Exchange reaction, cysteamine 1 Exchange reaction, cysteamine NA;cysteamine S-phosphate_P Source +cysteamine exchange 1 cysteamine exchange NA;cysteamine S-phosphate_P Source MNXR94721 1 23cGMP transport via diffusion (extracellular to periplasm) seed:rxn07927;2',3'-cyclic GMP_P Source MNXR94824 1 D-Glycerate 2-phosphate transport in/out via proton symport seed:rxn05474;2-phospho-D-glyceric acid_P Source MNXR94973 1 3-Phospho-D-glycerate transport in/out via proton symport seed:rxn05479;3-phosphonato-D-glycerate(3-)_P Source diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index ff1dae26..ffde8ce9 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -180862,7 +180862,7 @@ - +

Confidence Level: 1

diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index f8c5e46b..af2e9575 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -80454,7 +80454,7 @@ - confidence_score: 1 - !!omap - id: r_4442 - - name: Exchange reaction, cysteamine + - name: cysteamine exchange - metabolites: !!omap - s_4074: -1 - lower_bound: -1000 From a0c13bc35d9f7cc36a4cdc3d9acbdd1955418fcf Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Wed, 29 Aug 2018 14:03:58 +0200 Subject: [PATCH 20/27] style: readme file removed the details from lists of complementary scripts / complementary data, to avoid having to change the file everytime a new file gets added to the repo. --- README.md | 31 ++++--------------------------- 1 file changed, 4 insertions(+), 27 deletions(-) diff --git a/README.md b/README.md index 7aac4669..e0e93613 100644 --- a/README.md +++ b/README.md @@ -61,43 +61,20 @@ The model is available in `.xml`, `.txt`, `.yml`, `.mat` and `.xlsx` (the last 2 * `dependencies.txt`: Tracks versions of toolboxes & SBML used for saving the model. * `boundaryMets.txt`: Contains a list of all boundary metabolites in model, listing the id and name. -## Complementary Scripts +### Complementary Scripts * `missingFields`: Folder with functions for adding missing fields to the model. - * `addGeneNames.m`: Adds the field `geneNames` by extracting the data from KEGG. - * `addConfidenceScores.m`: Adds confidence scores based in a basic automatic criteria. - * `addSBOterms.m`: Adds SBO terms to metabolites and reactions based on the corresponding names. - * `getMissingFields.m`: Retrieves missing information (`rxnECNumbers` and `subSystems`) from KEGG & Swissprot. It uses `changeRules.m` for properly reading the gene-reaction rules, and `findInDB.m`, `getAllPath.m`, `findSubSystem.m` & `deleteRepeated.m` for reading the databases. The latter 4 functions are adapted versions of functions from the [GECKO toolbox](https://github.com/SysBioChalmers/GECKO). * `modelCuration`: Folder with curation functions. - * `addiSce926changes.m`: Updates the model to include curation from [the iSce926 model](http://www.maranasgroup.com/submission_models/iSce926.htm). - * `calculateContent.m`: Calculates the protein and carb fraction in the biomass pseudo-rxn. - * `changeBiomass.m`: Rescales the biomass composition for varying protein content in anaerobic case. Also changes GAM and NGAM. - * `checkMetBalance.m`: Shows rxns that consume/produce a given metabolite in the model. - * `makeFormulasCompliant.m`: Fixes the compliance problems of all metabolite formulas. - * `modelCorrections.m`: Corrects various issues in yeast7 (biomass composition, proton balance, Ox.Pho., GAM and NGAM). - * `takeOutFromFormula.m`: Takes away from formula each of the elements specified. - * `updateMetaboliteAnnotation.m`: Reads `metabolite_manual_curation.tsv` and updates the model with it. * `otherChanges`: Folder with other types of changes. - * `addSLIMErxns.m`: Replaces old ISA rxns with SLIME rxns, using [SLIMEr](https://github.com/SysBioChalmers/SLIMEr). - * `anaerobicModel.m`: Transforms the model to anaerobic conditions. - * `clusterBiomass.m`: Separates the biomass in 5 main components: protein, carbohydrate, lipid, RNA and DNA. - * `convertYmn2FBC2.m`: Converts yeast7 from COBRA-compatible SBML2 to FBC v2, thereby adding the missing annotation data, which could not be retained with the older COBRA versions. - * `getNewIndex.m`: Finds the highest index available in either metabolites or rxns, and then adds one to it, for creating any new species. * `increaseVersion.m`: Updates the version of the model in `version.txt` and as metaid in the `.xml` file. Saves the model as `.mat` and as `.xlsx` * `loadYeastModel.m`: Loads the yeast model from the `.xml` file for Matlab. * `loadYeastModel.py`: Loads the yeast model from the `.xml` file for Python. * `saveYeastModel.m`: Saves yeast model as a `.xml`, `.yml` and `.txt` file, and updates `boundaryMets.txt` and `dependencies.txt`. -## Complementary Data +### Complementary Data -* `databases` - * `kegg.tsv`: KEGG data for _S. cerevisiae_. - * `SGDgeneNames.tsv`: Short gene names for each gene ID. - * `swissprot.tsv`: SWISSPROT data for _S. cerevisiae_. -* `modelCuration` - * `iSce926curatedGeneRules.tsv`: Manually curated gene rules added to the model based on [the iSce926 model](http://www.maranasgroup.com/submission_models/iSce926.htm). - * `iSce926newGenes.tsv`: New genes added to the model based on [the iSce926 model](http://www.maranasgroup.com/submission_models/iSce926.htm). - * `metabolite_manual_curation.tsv`: All manually curated data added to metabolites. +* `databases`: Yeast data from different databases (KEGG, SGD, swissprot, etc). +* `modelCuration`: Data files used for performing curations to the model. Mostly lists of new rxns, mets or genes added (or fixed) in the model. ## Contributors From 3615afea30c94c82903adad8d65de8cc0db19677 Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Wed, 29 Aug 2018 16:04:26 +0200 Subject: [PATCH 21/27] refactor: skip gene fields no genes in this update are from yeast --- .../modelCuration/addBiologRxnToGEM.m | 19 ------------------- 1 file changed, 19 deletions(-) diff --git a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m index e65527c2..185ff13f 100644 --- a/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m +++ b/ComplementaryScripts/modelCuration/addBiologRxnToGEM.m @@ -143,25 +143,6 @@ model.rxnConfidenceScores(rxnIndex) = 1; %reactions without gene but needed for modelling end -% Add gene standard name for new genes: -fid = fopen('../../ComplementaryData/databases/SGDgeneNames.tsv'); -yeast_gene_annotation = textscan(fid,'%s %s','Delimiter','\t','HeaderLines',1); -fclose(fid); -geneIndex = zeros(1,1); -for i = 1: length(model.genes) - geneIndex = strcmp(yeast_gene_annotation{1}, model.genes{i}); - if sum(geneIndex) == 1 && ~isempty(yeast_gene_annotation{2}{geneIndex}) - model.geneNames{i} = yeast_gene_annotation{2}{geneIndex}; - else - model.geneNames{i} = model.genes{i}; - end -end - -% Add protein name for genes: -for i = 1:length(model.genes) - model.proteins{i} = strcat('COBRAProtein',num2str(i)); -end - % Save model: cd .. saveYeastModel(model) From dd4e43f03e60978995e6e4f0a9c1f4102c07889f Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Thu, 30 Aug 2018 11:12:45 +0200 Subject: [PATCH 22/27] fix-rxn.annot: transport names --- ComplementaryData/modelCuration/Biolog_newRxnProp.tsv | 4 ++-- ModelFiles/xml/yeastGEM.xml | 4 ++-- ModelFiles/yml/yeastGEM.yml | 4 ++-- README.md | 2 +- 4 files changed, 7 insertions(+), 7 deletions(-) diff --git a/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv b/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv index 13597128..931b7c29 100644 --- a/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv +++ b/ComplementaryData/modelCuration/Biolog_newRxnProp.tsv @@ -136,12 +136,12 @@ MNXR137133_cv 1 L-alanylglycine transport via proton antiport seed:rxn12625;A N-acetyl-L-glutamate transport 1 N-acetyl-L-glutamate transport NA;N-acetyl-L-glutamate_N Source N-acetyl-L-glutamate transport, mitochondrion 1 N-acetyl-L-glutamate transport NA;N-acetyl-L-glutamate_N Source MNXR137094 1 Lipoamide transport via proton symport seed:rxn12577;lipoamide_S Source -MNXR101483 1 L-methionine S-oxide diffusion (extracellular) seed:rxn08915;L-Methionine S-oxide_S Source +MNXR101483 1 L-methionine S-oxide transport via diffusion (extracellular) seed:rxn08915;L-Methionine S-oxide_S Source Gly-Asn transport via proton symport (cytosol to vacuole) 1 Gly-Asn transport via proton symport NA;Gly-Asn_N Source MNXR137130 1 Cysteamine transport via proton antiport seed:rxn12622;cysteamine S-phosphate_P Source Hydrogen sulfide oxidation 0 Hydrogen sulfide oxidation NA;general sulfur metabolism_S Source MNXR95704 1 L-alanine transport in via proton symport rhea:29443;L-alanine_N Source -MNXR100368 1 Glycine mitochondrial transport rhea:28899;L-glycine_N Source +MNXR100368 1 Glycine transport (vacuole) rhea:28899;L-glycine_N Source MNXR104382 1 ( YJR130C or YLL058W or YML082W ) O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide) 2.5.1.-;2.5.1.48 R01288 rhea:27826;L-methionine_N Source MNXR94843 0 4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating) 1.13.11.27 R02521 rhea:16189;L-tyrosine_N Source MNXR100628 0 Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) 1.13.11.5 R02519 rhea:15449;L-tyrosine_N Source diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index ffde8ce9..e9078443 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -181903,7 +181903,7 @@ - +

Confidence Level: 1

@@ -182046,7 +182046,7 @@ - +

Confidence Level: 1

diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index af2e9575..1fe21563 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -80817,7 +80817,7 @@ - confidence_score: 1 - !!omap - id: r_4478 - - name: L-methionine S-oxide diffusion (extracellular) + - name: L-methionine S-oxide transport via diffusion (extracellular) - metabolites: !!omap - s_3837: 1 - s_4176: -1 @@ -80870,7 +80870,7 @@ - confidence_score: 1 - !!omap - id: r_4483 - - name: Glycine mitochondrial transport + - name: Glycine transport (vacuole) - metabolites: !!omap - s_0794: -1 - s_0802: 1 diff --git a/README.md b/README.md index 0d31a7a0..6d17c5d7 100644 --- a/README.md +++ b/README.md @@ -10,7 +10,7 @@ This repository contains the current consensus genome-scale metabolic model of _ **GEM Category:** Species; **Utilisation:** predictive simulation, multi-omics integrative analysis, _in silico_ strain design, model template; **Field:** metabolic-network reconstruction; **Type of Model:** curated, reconstruction; **Model Source:** [Yeast 7.6](https://sourceforge.net/projects/yeast/); **Taxonomy:** _Saccharomyces cerevisiae_; **Metabolic System:** General Metabolism; **Condition:** aerobic, glucose-limited, defined media, maximization of growth. -* Last update: 2018-08-29 +* Last update: 2018-08-30 * Main Model Descriptors: From e6cab9cb5afd6cc1c0e978a3374bdb9cd270ba2f Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Thu, 30 Aug 2018 14:18:14 +0200 Subject: [PATCH 23/27] chore: update RAVEN extra fields added to .yml file: met SBO terms + rxn/met metaNetX ids. NOTE: made with RAVEN @ devel --- ModelFiles/dependencies.txt | 2 +- ModelFiles/yml/yeastGEM.yml | 8528 +++++++++++++++++++++++++++++++++++ 2 files changed, 8529 insertions(+), 1 deletion(-) diff --git a/ModelFiles/dependencies.txt b/ModelFiles/dependencies.txt index 43da025a..e5fb14da 100644 --- a/ModelFiles/dependencies.txt +++ b/ModelFiles/dependencies.txt @@ -1,6 +1,6 @@ MATLAB 9.4.0.813654 (R2018a) libSBML 5.17.0 -RAVEN_toolbox 2.0.0 +RAVEN_toolbox unknown COBRA_toolbox commit ef3990e SBML_level 3 SBML_version 1 diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index 1fe21563..e5c8697a 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -9,6 +9,7 @@ - annotation: !!omap - chebi: CHEBI:37671 - kegg.compound: C00965 + - sbo: SBO:0000247 - !!omap - id: s_0002 - name: (1->3)-beta-D-glucan @@ -18,6 +19,7 @@ - annotation: !!omap - chebi: CHEBI:37671 - kegg.compound: C00965 + - sbo: SBO:0000247 - !!omap - id: s_0003 - name: (1->3)-beta-D-glucan @@ -27,6 +29,7 @@ - annotation: !!omap - chebi: CHEBI:37671 - kegg.compound: C00965 + - sbo: SBO:0000247 - !!omap - id: s_0004 - name: (1->6)-beta-D-glucan @@ -36,6 +39,7 @@ - annotation: !!omap - chebi: CHEBI:27380 - kegg.compound: C02493 + - sbo: SBO:0000247 - !!omap - id: s_0006 - name: (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate @@ -45,6 +49,7 @@ - annotation: !!omap - chebi: CHEBI:57602 - kegg.compound: C04807 + - sbo: SBO:0000247 - !!omap - id: s_0007 - name: (2E)-3-(methoxycarbonyl)pent-2-enedioic acid @@ -54,6 +59,7 @@ - annotation: !!omap - chebi: CHEBI:57470 - kegg.compound: C11514 + - sbo: SBO:0000247 - !!omap - id: s_0008 - name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate @@ -63,6 +69,7 @@ - annotation: !!omap - chebi: CHEBI:49258 - kegg.compound: C06007 + - sbo: SBO:0000247 - !!omap - id: s_0009 - name: (2R,3S)-3-isopropylmalate @@ -72,6 +79,7 @@ - annotation: !!omap - chebi: CHEBI:35121 - kegg.compound: C04411 + - sbo: SBO:0000247 - !!omap - id: s_0010 - name: (2S)-2-isopropyl-3-oxosuccinate @@ -81,6 +89,7 @@ - annotation: !!omap - chebi: CHEBI:17214 - kegg.compound: C04236 + - sbo: SBO:0000247 - !!omap - id: s_0011 - name: (2S)-2-isopropyl-3-oxosuccinate @@ -90,6 +99,7 @@ - annotation: !!omap - chebi: CHEBI:17214 - kegg.compound: C04236 + - sbo: SBO:0000247 - !!omap - id: s_0012 - name: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid @@ -99,6 +109,7 @@ - annotation: !!omap - chebi: CHEBI:57429 - kegg.compound: C04593 + - sbo: SBO:0000247 - !!omap - id: s_0013 - name: (5S,6S)-di-HETE @@ -107,6 +118,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53026 + - sbo: SBO:0000247 - !!omap - id: s_0014 - name: (5S,6S)-di-HETE @@ -115,6 +127,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53026 + - sbo: SBO:0000247 - !!omap - id: s_0015 - name: (N(omega)-L-arginino)succinic acid @@ -124,6 +137,7 @@ - annotation: !!omap - chebi: CHEBI:57472 - kegg.compound: C03406 + - sbo: SBO:0000247 - !!omap - id: s_0016 - name: (R)-2,3-dihydroxy-3-methylbutanoate @@ -133,6 +147,7 @@ - annotation: !!omap - chebi: CHEBI:49072 - kegg.compound: C04272 + - sbo: SBO:0000247 - !!omap - id: s_0017 - name: (R)-4'-phosphopantothenic acid @@ -142,6 +157,7 @@ - annotation: !!omap - chebi: CHEBI:15905 - kegg.compound: C03492 + - sbo: SBO:0000247 - !!omap - id: s_0018 - name: (R)-5-diphosphomevalonic acid @@ -151,6 +167,7 @@ - annotation: !!omap - chebi: CHEBI:57557 - kegg.compound: C01143 + - sbo: SBO:0000247 - !!omap - id: s_0019 - name: (R)-5-phosphomevalonic acid @@ -160,6 +177,7 @@ - annotation: !!omap - chebi: CHEBI:58146 - kegg.compound: C01107 + - sbo: SBO:0000247 - !!omap - id: s_0020 - name: (R)-acetoin @@ -169,6 +187,7 @@ - annotation: !!omap - chebi: CHEBI:15686 - kegg.compound: C00810 + - sbo: SBO:0000247 - !!omap - id: s_0021 - name: (R)-carnitine @@ -178,6 +197,7 @@ - annotation: !!omap - chebi: CHEBI:16347 - kegg.compound: C00318 + - sbo: SBO:0000247 - !!omap - id: s_0022 - name: (R)-carnitine @@ -187,6 +207,7 @@ - annotation: !!omap - chebi: CHEBI:16347 - kegg.compound: C00318 + - sbo: SBO:0000247 - !!omap - id: s_0023 - name: (R)-carnitine @@ -196,6 +217,7 @@ - annotation: !!omap - chebi: CHEBI:16347 - kegg.compound: C00318 + - sbo: SBO:0000247 - !!omap - id: s_0024 - name: (R)-carnitine @@ -205,6 +227,7 @@ - annotation: !!omap - chebi: CHEBI:16347 - kegg.compound: C00318 + - sbo: SBO:0000247 - !!omap - id: s_0025 - name: (R)-lactate @@ -214,6 +237,7 @@ - annotation: !!omap - chebi: CHEBI:16004 - kegg.compound: C00256 + - sbo: SBO:0000247 - !!omap - id: s_0026 - name: (R)-lactate @@ -223,6 +247,7 @@ - annotation: !!omap - chebi: CHEBI:16004 - kegg.compound: C00256 + - sbo: SBO:0000247 - !!omap - id: s_0027 - name: (R)-lactate @@ -232,6 +257,7 @@ - annotation: !!omap - chebi: CHEBI:16004 - kegg.compound: C00256 + - sbo: SBO:0000247 - !!omap - id: s_0028 - name: (R)-mevalonate @@ -241,6 +267,7 @@ - annotation: !!omap - chebi: CHEBI:36464 - kegg.compound: C00418 + - sbo: SBO:0000247 - !!omap - id: s_0029 - name: (R)-mevalonate @@ -250,6 +277,7 @@ - annotation: !!omap - chebi: CHEBI:36464 - kegg.compound: C00418 + - sbo: SBO:0000247 - !!omap - id: s_0030 - name: (R)-pantoate @@ -259,6 +287,7 @@ - annotation: !!omap - chebi: CHEBI:15980 - kegg.compound: C00522 + - sbo: SBO:0000247 - !!omap - id: s_0031 - name: (R)-pantothenate @@ -268,6 +297,7 @@ - annotation: !!omap - chebi: CHEBI:29032 - kegg.compound: C00864 + - sbo: SBO:0000247 - !!omap - id: s_0032 - name: (R)-pantothenate @@ -277,6 +307,7 @@ - annotation: !!omap - chebi: CHEBI:29032 - kegg.compound: C00864 + - sbo: SBO:0000247 - !!omap - id: s_0033 - name: (R)-S-lactoylglutathione @@ -286,6 +317,7 @@ - annotation: !!omap - chebi: CHEBI:57474 - kegg.compound: C03451 + - sbo: SBO:0000247 - !!omap - id: s_0034 - name: (R)-S-lactoylglutathione @@ -295,6 +327,7 @@ - annotation: !!omap - chebi: CHEBI:57474 - kegg.compound: C03451 + - sbo: SBO:0000247 - !!omap - id: s_0035 - name: (R,R)-2,3-butanediol @@ -304,6 +337,7 @@ - annotation: !!omap - chebi: CHEBI:16982 - kegg.compound: C03044 + - sbo: SBO:0000247 - !!omap - id: s_0036 - name: (R,R)-2,3-butanediol @@ -313,6 +347,7 @@ - annotation: !!omap - chebi: CHEBI:16982 - kegg.compound: C03044 + - sbo: SBO:0000247 - !!omap - id: s_0037 - name: (S)-2,3-epoxysqualene @@ -322,6 +357,7 @@ - annotation: !!omap - chebi: CHEBI:15441 - kegg.compound: C01054 + - sbo: SBO:0000247 - !!omap - id: s_0038 - name: (S)-2,3-epoxysqualene @@ -331,6 +367,7 @@ - annotation: !!omap - chebi: CHEBI:15441 - kegg.compound: C01054 + - sbo: SBO:0000247 - !!omap - id: s_0039 - name: (S)-2-acetyl-2-hydroxybutanoate @@ -340,6 +377,7 @@ - annotation: !!omap - chebi: CHEBI:49256 - kegg.compound: C06006 + - sbo: SBO:0000247 - !!omap - id: s_0042 - name: (R)-3-hydroxydecanoyl-CoA @@ -349,6 +387,7 @@ - annotation: !!omap - chebi: CHEBI:28325 - kegg.compound: C05264 + - sbo: SBO:0000247 - !!omap - id: s_0045 - name: (S)-3-hydroxyhexacosanoyl-CoA @@ -357,6 +396,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52976 + - sbo: SBO:0000247 - !!omap - id: s_0048 - name: (R)-3-hydroxylauroyl-CoA @@ -366,6 +406,7 @@ - annotation: !!omap - chebi: CHEBI:27668 - kegg.compound: C05262 + - sbo: SBO:0000247 - !!omap - id: s_0051 - name: (S)-3-hydroxypalmitoyl-CoA @@ -375,6 +416,7 @@ - annotation: !!omap - chebi: CHEBI:27402 - kegg.compound: C05258 + - sbo: SBO:0000247 - !!omap - id: s_0054 - name: (S)-3-hydroxytetradecanoyl-CoA @@ -384,6 +426,7 @@ - annotation: !!omap - chebi: CHEBI:27466 - kegg.compound: C05260 + - sbo: SBO:0000247 - !!omap - id: s_0056 - name: (S)-3-methyl-2-oxopentanoate @@ -393,6 +436,7 @@ - annotation: !!omap - chebi: CHEBI:35146 - kegg.compound: C00671 + - sbo: SBO:0000247 - !!omap - id: s_0058 - name: (S)-3-methyl-2-oxopentanoate @@ -402,6 +446,7 @@ - annotation: !!omap - chebi: CHEBI:35146 - kegg.compound: C00671 + - sbo: SBO:0000247 - !!omap - id: s_0060 - name: (S)-3-methyl-2-oxopentanoate @@ -411,6 +456,7 @@ - annotation: !!omap - chebi: CHEBI:35146 - kegg.compound: C00671 + - sbo: SBO:0000247 - !!omap - id: s_0061 - name: (S)-dihydroorotate @@ -420,6 +466,7 @@ - annotation: !!omap - chebi: CHEBI:30864 - kegg.compound: C00337 + - sbo: SBO:0000247 - !!omap - id: s_0062 - name: (S)-lactaldehyde @@ -429,6 +476,7 @@ - annotation: !!omap - chebi: CHEBI:18041 - kegg.compound: C00424 + - sbo: SBO:0000247 - !!omap - id: s_0063 - name: (S)-lactate @@ -438,6 +486,7 @@ - annotation: !!omap - chebi: CHEBI:16651 - kegg.compound: C00186 + - sbo: SBO:0000247 - !!omap - id: s_0064 - name: (S)-lactate @@ -447,6 +496,7 @@ - annotation: !!omap - chebi: CHEBI:16651 - kegg.compound: C00186 + - sbo: SBO:0000247 - !!omap - id: s_0065 - name: (S)-lactate @@ -456,6 +506,7 @@ - annotation: !!omap - chebi: CHEBI:16651 - kegg.compound: C00186 + - sbo: SBO:0000247 - !!omap - id: s_0066 - name: (S)-malate @@ -465,6 +516,7 @@ - annotation: !!omap - chebi: CHEBI:15589 - kegg.compound: C00149 + - sbo: SBO:0000247 - !!omap - id: s_0067 - name: (S)-malate @@ -474,6 +526,7 @@ - annotation: !!omap - chebi: CHEBI:15589 - kegg.compound: C00149 + - sbo: SBO:0000247 - !!omap - id: s_0068 - name: (S)-malate @@ -483,6 +536,7 @@ - annotation: !!omap - chebi: CHEBI:15589 - kegg.compound: C00149 + - sbo: SBO:0000247 - !!omap - id: s_0069 - name: (S)-malate @@ -492,6 +546,7 @@ - annotation: !!omap - chebi: CHEBI:15589 - kegg.compound: C00149 + - sbo: SBO:0000247 - !!omap - id: s_0075 - name: 1,3-bisphospho-D-glycerate @@ -501,6 +556,7 @@ - annotation: !!omap - chebi: CHEBI:57604 - kegg.compound: C00236 + - sbo: SBO:0000247 - !!omap - id: s_0076 - name: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate @@ -510,6 +566,7 @@ - annotation: !!omap - chebi: CHEBI:58613 - kegg.compound: C01302 + - sbo: SBO:0000247 - !!omap - id: s_0077 - name: 1-(5-phospho-D-ribosyl)-5-[(5-phospho-D-ribosylamino)methylideneamino]imidazole-4-carboxamide @@ -519,6 +576,7 @@ - annotation: !!omap - chebi: CHEBI:58435 - kegg.compound: C04896 + - sbo: SBO:0000247 - !!omap - id: s_0078 - name: 1-(5-phosphoribosyl)-5'-AMP @@ -528,6 +586,7 @@ - annotation: !!omap - chebi: CHEBI:59457 - kegg.compound: C02741 + - sbo: SBO:0000247 - !!omap - id: s_0079 - name: 1-(sn-glycero-3-phospho)-1D-myo-inositol @@ -537,6 +596,7 @@ - annotation: !!omap - chebi: CHEBI:58444 - kegg.compound: C01225 + - sbo: SBO:0000247 - !!omap - id: s_0080 - name: 1-(sn-glycero-3-phospho)-1D-myo-inositol @@ -546,6 +606,7 @@ - annotation: !!omap - chebi: CHEBI:58444 - kegg.compound: C01225 + - sbo: SBO:0000247 - !!omap - id: s_0084 - name: 1-acylglycerophosphocholine @@ -555,6 +616,7 @@ - annotation: !!omap - chebi: CHEBI:11230 - kegg.compound: C04230 + - sbo: SBO:0000247 - !!omap - id: s_0086 - name: 1-C-(indol-3-yl)glycerol 3-phosphate @@ -564,6 +626,7 @@ - annotation: !!omap - chebi: CHEBI:60820 - kegg.compound: C03506 + - sbo: SBO:0000247 - !!omap - id: s_0087 - name: 1-methylnicotinamide @@ -573,6 +636,7 @@ - annotation: !!omap - chebi: CHEBI:16797 - kegg.compound: C02918 + - sbo: SBO:0000247 - !!omap - id: s_0089 - name: 1-phosphatidyl-1D-myo-inositol backbone @@ -582,6 +646,7 @@ - annotation: !!omap - chebi: CHEBI:57880 - kegg.compound: C01194 + - sbo: SBO:0000649 - !!omap - id: s_0116 - name: 1-pyrroline-3-hydroxy-5-carboxylic acid @@ -591,6 +656,7 @@ - annotation: !!omap - chebi: CHEBI:58509 - kegg.compound: C04281 + - sbo: SBO:0000247 - !!omap - id: s_0117 - name: 1-pyrroline-3-hydroxy-5-carboxylic acid @@ -600,6 +666,7 @@ - annotation: !!omap - chebi: CHEBI:58509 - kegg.compound: C04281 + - sbo: SBO:0000247 - !!omap - id: s_0118 - name: 1-pyrroline-5-carboxylate @@ -609,6 +676,7 @@ - annotation: !!omap - chebi: CHEBI:15893 - kegg.compound: C04322 + - sbo: SBO:0000247 - !!omap - id: s_0119 - name: 1-pyrroline-5-carboxylate @@ -618,6 +686,7 @@ - annotation: !!omap - chebi: CHEBI:15893 - kegg.compound: C04322 + - sbo: SBO:0000247 - !!omap - id: s_0120 - name: 10-formyl-THF @@ -627,6 +696,7 @@ - annotation: !!omap - chebi: CHEBI:57454 - kegg.compound: C00234 + - sbo: SBO:0000247 - !!omap - id: s_0121 - name: 10-formyl-THF @@ -636,6 +706,7 @@ - annotation: !!omap - chebi: CHEBI:57454 - kegg.compound: C00234 + - sbo: SBO:0000247 - !!omap - id: s_0122 - name: 14-demethyllanosterol @@ -645,6 +716,7 @@ - annotation: !!omap - chebi: CHEBI:18364 - kegg.compound: C05108 + - sbo: SBO:0000247 - !!omap - id: s_0123 - name: 1D-myo-inositol 1,3,4,5-tetrakisphosphate @@ -654,6 +726,7 @@ - annotation: !!omap - chebi: CHEBI:57895 - kegg.compound: C01272 + - sbo: SBO:0000247 - !!omap - id: s_0124 - name: 1D-myo-inositol 1,4,5,6-tetrakisphosphate @@ -663,6 +736,7 @@ - annotation: !!omap - chebi: CHEBI:57627 - kegg.compound: C11555 + - sbo: SBO:0000247 - !!omap - id: s_0125 - name: 1D-myo-inositol 1,4,5-trisphosphate @@ -672,6 +746,7 @@ - annotation: !!omap - chebi: CHEBI:203600 - kegg.compound: C01245 + - sbo: SBO:0000247 - !!omap - id: s_0126 - name: 1D-myo-inositol 1-phosphate @@ -681,6 +756,7 @@ - annotation: !!omap - chebi: CHEBI:58433 - kegg.compound: C01177 + - sbo: SBO:0000247 - !!omap - id: s_0127 - name: 1D-myo-inositol 1-phosphate @@ -690,6 +766,7 @@ - annotation: !!omap - chebi: CHEBI:58433 - kegg.compound: C01177 + - sbo: SBO:0000247 - !!omap - id: s_0129 - name: 1D-myo-inositol 3-phosphate @@ -699,6 +776,7 @@ - annotation: !!omap - chebi: CHEBI:58401 - kegg.compound: C04006 + - sbo: SBO:0000247 - !!omap - id: s_0131 - name: 2',3'-cyclic AMP @@ -708,6 +786,7 @@ - annotation: !!omap - chebi: CHEBI:60879 - kegg.compound: C02353 + - sbo: SBO:0000247 - !!omap - id: s_0132 - name: 2'-deoxyadenosine @@ -717,6 +796,7 @@ - annotation: !!omap - chebi: CHEBI:17256 - kegg.compound: C00559 + - sbo: SBO:0000247 - !!omap - id: s_0133 - name: 2'-deoxyadenosine @@ -726,6 +806,7 @@ - annotation: !!omap - chebi: CHEBI:17256 - kegg.compound: C00559 + - sbo: SBO:0000247 - !!omap - id: s_0134 - name: 2'-deoxyguanosine @@ -735,6 +816,7 @@ - annotation: !!omap - chebi: CHEBI:17172 - kegg.compound: C00330 + - sbo: SBO:0000247 - !!omap - id: s_0135 - name: 2'-deoxyguanosine @@ -744,6 +826,7 @@ - annotation: !!omap - chebi: CHEBI:17172 - kegg.compound: C00330 + - sbo: SBO:0000247 - !!omap - id: s_0136 - name: 2'-deoxyinosine @@ -753,6 +836,7 @@ - annotation: !!omap - chebi: CHEBI:28997 - kegg.compound: C05512 + - sbo: SBO:0000247 - !!omap - id: s_0137 - name: 2'-deoxyinosine @@ -762,6 +846,7 @@ - annotation: !!omap - chebi: CHEBI:28997 - kegg.compound: C05512 + - sbo: SBO:0000247 - !!omap - id: s_0138 - name: 2'-deoxyuridine @@ -771,6 +856,7 @@ - annotation: !!omap - chebi: CHEBI:16450 - kegg.compound: C00526 + - sbo: SBO:0000247 - !!omap - id: s_0139 - name: 2'-deoxyuridine @@ -780,6 +866,7 @@ - annotation: !!omap - chebi: CHEBI:16450 - kegg.compound: C00526 + - sbo: SBO:0000247 - !!omap - id: s_0140 - name: 2,3-bisphospho-D-glyceric acid @@ -789,6 +876,7 @@ - annotation: !!omap - chebi: CHEBI:58248 - kegg.compound: C01159 + - sbo: SBO:0000247 - !!omap - id: s_0141 - name: 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine @@ -798,6 +886,7 @@ - annotation: !!omap - chebi: CHEBI:58614 - kegg.compound: C01304 + - sbo: SBO:0000247 - !!omap - id: s_0142 - name: 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone @@ -806,6 +895,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52957 + - sbo: SBO:0000247 - !!omap - id: s_0143 - name: 2-(3-amino-3-carboxypropyl)-L-histidine @@ -815,6 +905,7 @@ - annotation: !!omap - chebi: CHEBI:17144 - kegg.compound: C04441 + - sbo: SBO:0000247 - !!omap - id: s_0144 - name: 2-[3-carboxy-3-(methylammonio)propyl]-L-histidine @@ -824,6 +915,7 @@ - annotation: !!omap - chebi: CHEBI:57784 - kegg.compound: C04692 + - sbo: SBO:0000247 - !!omap - id: s_0145 - name: 2-acetamido-5-oxopentanoate @@ -833,6 +925,7 @@ - annotation: !!omap - chebi: CHEBI:29123 - kegg.compound: C01250 + - sbo: SBO:0000247 - !!omap - id: s_0146 - name: 2-acetyllactic acid @@ -842,6 +935,7 @@ - annotation: !!omap - chebi: CHEBI:57774 - kegg.compound: C00900 + - sbo: SBO:0000247 - !!omap - id: s_0147 - name: 2-amino-3-carboxymuconate-6-semialdehyde @@ -850,6 +944,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:29044 + - sbo: SBO:0000247 - !!omap - id: s_0148 - name: 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol @@ -859,6 +954,7 @@ - annotation: !!omap - chebi: CHEBI:17083 - kegg.compound: C01300 + - sbo: SBO:0000247 - !!omap - id: s_0149 - name: 2-dehydropantoate @@ -868,6 +964,7 @@ - annotation: !!omap - chebi: CHEBI:11561 - kegg.compound: C00966 + - sbo: SBO:0000247 - !!omap - id: s_0150 - name: 2-dehydropantoate @@ -877,6 +974,7 @@ - annotation: !!omap - chebi: CHEBI:11561 - kegg.compound: C00966 + - sbo: SBO:0000247 - !!omap - id: s_0152 - name: 2-deoxy-D-ribose @@ -886,6 +984,7 @@ - annotation: !!omap - chebi: CHEBI:28816 - kegg.compound: C01801 + - sbo: SBO:0000247 - !!omap - id: s_0153 - name: 2-deoxy-D-ribose 5-phosphate @@ -895,6 +994,7 @@ - annotation: !!omap - chebi: CHEBI:57651 - kegg.compound: C00673 + - sbo: SBO:0000247 - !!omap - id: s_0154 - name: 2-hexaprenyl-5-hydroxy-6-methoxy-3-methyl-1,4-benzoquinone @@ -904,6 +1004,7 @@ - annotation: !!omap - chebi: CHEBI:28753 - kegg.compound: C05805 + - sbo: SBO:0000247 - !!omap - id: s_0155 - name: 2-hexaprenyl-6-methoxy-1,4-benzoquinone @@ -913,6 +1014,7 @@ - annotation: !!omap - chebi: CHEBI:27752 - kegg.compound: C05803 + - sbo: SBO:0000247 - !!omap - id: s_0156 - name: 2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone @@ -922,6 +1024,7 @@ - annotation: !!omap - chebi: CHEBI:28711 - kegg.compound: C05804 + - sbo: SBO:0000247 - !!omap - id: s_0157 - name: 2-hexaprenyl-6-methoxyphenol @@ -931,6 +1034,7 @@ - annotation: !!omap - chebi: CHEBI:1109 - kegg.compound: C05802 + - sbo: SBO:0000247 - !!omap - id: s_0158 - name: 2-hydroxy-3-oxobutyl phosphate @@ -940,6 +1044,7 @@ - annotation: !!omap - chebi: CHEBI:50606 - kegg.compound: C15556 + - sbo: SBO:0000247 - !!omap - id: s_0161 - name: 2-hydroxyhexadecanal @@ -948,6 +1053,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:50626 + - sbo: SBO:0000247 - !!omap - id: s_0162 - name: 2-isopropylmalate @@ -957,6 +1063,7 @@ - annotation: !!omap - chebi: CHEBI:28107 - kegg.compound: C02504 + - sbo: SBO:0000247 - !!omap - id: s_0163 - name: 2-isopropylmalate @@ -966,6 +1073,7 @@ - annotation: !!omap - chebi: CHEBI:28107 - kegg.compound: C02504 + - sbo: SBO:0000247 - !!omap - id: s_0164 - name: 2-isopropylmalate @@ -975,6 +1083,7 @@ - annotation: !!omap - chebi: CHEBI:28107 - kegg.compound: C02504 + - sbo: SBO:0000247 - !!omap - id: s_0165 - name: 2-isopropylmaleic acid @@ -984,6 +1093,7 @@ - annotation: !!omap - chebi: CHEBI:58085 - kegg.compound: C02631 + - sbo: SBO:0000247 - !!omap - id: s_0166 - name: 2-methylbutanal @@ -993,6 +1103,7 @@ - annotation: !!omap - chebi: CHEBI:16182 - kegg.compound: C02223 + - sbo: SBO:0000247 - !!omap - id: s_0167 - name: 2-methylbutanal @@ -1002,6 +1113,7 @@ - annotation: !!omap - chebi: CHEBI:16182 - kegg.compound: C02223 + - sbo: SBO:0000247 - !!omap - id: s_0168 - name: 2-methylbutanal @@ -1011,6 +1123,7 @@ - annotation: !!omap - chebi: CHEBI:16182 - kegg.compound: C02223 + - sbo: SBO:0000247 - !!omap - id: s_0169 - name: 2-methylbutanol @@ -1019,6 +1132,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:48945 + - sbo: SBO:0000247 - !!omap - id: s_0170 - name: 2-methylbutanol @@ -1027,6 +1141,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:48945 + - sbo: SBO:0000247 - !!omap - id: s_0171 - name: 2-methylbutanol @@ -1035,6 +1150,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:48945 + - sbo: SBO:0000247 - !!omap - id: s_0172 - name: 2-methylbutyl acetate @@ -1043,6 +1159,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:50585 + - sbo: SBO:0000247 - !!omap - id: s_0173 - name: 2-methylbutyl acetate @@ -1051,6 +1168,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:50585 + - sbo: SBO:0000247 - !!omap - id: s_0174 - name: 2-methylcitrate @@ -1060,6 +1178,7 @@ - annotation: !!omap - chebi: CHEBI:15598 - kegg.compound: C02225 + - sbo: SBO:0000247 - !!omap - id: s_0176 - name: 2-oxoadipic acid @@ -1069,6 +1188,7 @@ - annotation: !!omap - chebi: CHEBI:57499 - kegg.compound: C00322 + - sbo: SBO:0000247 - !!omap - id: s_0177 - name: 2-oxoadipic acid @@ -1078,6 +1198,7 @@ - annotation: !!omap - chebi: CHEBI:57499 - kegg.compound: C00322 + - sbo: SBO:0000247 - !!omap - id: s_0178 - name: 2-oxobutanoate @@ -1087,6 +1208,7 @@ - annotation: !!omap - chebi: CHEBI:16763 - kegg.compound: C00109 + - sbo: SBO:0000247 - !!omap - id: s_0179 - name: 2-oxobutanoate @@ -1096,6 +1218,7 @@ - annotation: !!omap - chebi: CHEBI:16763 - kegg.compound: C00109 + - sbo: SBO:0000247 - !!omap - id: s_0180 - name: 2-oxoglutarate @@ -1105,6 +1228,7 @@ - annotation: !!omap - chebi: CHEBI:16810 - kegg.compound: C00026 + - sbo: SBO:0000247 - !!omap - id: s_0181 - name: 2-oxoglutarate @@ -1114,6 +1238,7 @@ - annotation: !!omap - chebi: CHEBI:16810 - kegg.compound: C00026 + - sbo: SBO:0000247 - !!omap - id: s_0182 - name: 2-oxoglutarate @@ -1123,6 +1248,7 @@ - annotation: !!omap - chebi: CHEBI:16810 - kegg.compound: C00026 + - sbo: SBO:0000247 - !!omap - id: s_0183 - name: 2-oxoglutarate @@ -1132,6 +1258,7 @@ - annotation: !!omap - chebi: CHEBI:16810 - kegg.compound: C00026 + - sbo: SBO:0000247 - !!omap - id: s_0184 - name: 2-oxoglutarate @@ -1141,6 +1268,7 @@ - annotation: !!omap - chebi: CHEBI:16810 - kegg.compound: C00026 + - sbo: SBO:0000247 - !!omap - id: s_0185 - name: 2-phenylethanol @@ -1150,6 +1278,7 @@ - annotation: !!omap - chebi: CHEBI:49000 - kegg.compound: C05853 + - sbo: SBO:0000247 - !!omap - id: s_0186 - name: 2-phenylethanol @@ -1159,6 +1288,7 @@ - annotation: !!omap - chebi: CHEBI:49000 - kegg.compound: C05853 + - sbo: SBO:0000247 - !!omap - id: s_0187 - name: 2-phenylethanol @@ -1168,6 +1298,7 @@ - annotation: !!omap - chebi: CHEBI:49000 - kegg.compound: C05853 + - sbo: SBO:0000247 - !!omap - id: s_0188 - name: 2-phospho-D-glyceric acid @@ -1177,6 +1308,7 @@ - annotation: !!omap - chebi: CHEBI:58289 - kegg.compound: C00631 + - sbo: SBO:0000247 - !!omap - id: s_0189 - name: geranylgeranyl diphosphate @@ -1186,6 +1318,7 @@ - annotation: !!omap - chebi: CHEBI:58756 - kegg.compound: C00353 + - sbo: SBO:0000247 - !!omap - id: s_0190 - name: farnesyl diphosphate @@ -1195,6 +1328,7 @@ - annotation: !!omap - chebi: CHEBI:175763 - kegg.compound: C00448 + - sbo: SBO:0000247 - !!omap - id: s_0191 - name: farnesyl diphosphate @@ -1204,6 +1338,7 @@ - annotation: !!omap - chebi: CHEBI:175763 - kegg.compound: C00448 + - sbo: SBO:0000247 - !!omap - id: s_0192 - name: 3',5'-cyclic AMP @@ -1213,6 +1348,7 @@ - annotation: !!omap - chebi: CHEBI:58165 - kegg.compound: C00575 + - sbo: SBO:0000247 - !!omap - id: s_0193 - name: 3',5'-cyclic CMP @@ -1222,6 +1358,7 @@ - annotation: !!omap - chebi: CHEBI:58003 - kegg.compound: C00941 + - sbo: SBO:0000247 - !!omap - id: s_0194 - name: 3',5'-cyclic dAMP @@ -1231,6 +1368,7 @@ - annotation: !!omap - chebi: CHEBI:28074 - kegg.compound: C00968 + - sbo: SBO:0000247 - !!omap - id: s_0195 - name: 3',5'-cyclic GMP @@ -1240,6 +1378,7 @@ - annotation: !!omap - chebi: CHEBI:57746 - kegg.compound: C00942 + - sbo: SBO:0000247 - !!omap - id: s_0196 - name: 3',5'-cyclic IMP @@ -1249,6 +1388,7 @@ - annotation: !!omap - chebi: CHEBI:27541 - kegg.compound: C00943 + - sbo: SBO:0000247 - !!omap - id: s_0197 - name: 3'-dephospho-CoA @@ -1258,6 +1398,7 @@ - annotation: !!omap - chebi: CHEBI:57328 - kegg.compound: C00882 + - sbo: SBO:0000247 - !!omap - id: s_0200 - name: 3'-dephospho-CoA @@ -1267,6 +1408,7 @@ - annotation: !!omap - chebi: CHEBI:57328 - kegg.compound: C00882 + - sbo: SBO:0000247 - !!omap - id: s_0201 - name: 3'-phospho-5'-adenylyl sulfate @@ -1276,6 +1418,7 @@ - annotation: !!omap - chebi: CHEBI:58339 - kegg.compound: C00053 + - sbo: SBO:0000247 - !!omap - id: s_0204 - name: 3-(4-hydroxyphenyl)pyruvate @@ -1285,6 +1428,7 @@ - annotation: !!omap - chebi: CHEBI:36242 - kegg.compound: C01179 + - sbo: SBO:0000247 - !!omap - id: s_0206 - name: 3-(4-hydroxyphenyl)pyruvate @@ -1294,6 +1438,7 @@ - annotation: !!omap - chebi: CHEBI:36242 - kegg.compound: C01179 + - sbo: SBO:0000247 - !!omap - id: s_0207 - name: 3-(imidazol-4-yl)-2-oxopropyl dihydrogen phosphate @@ -1303,6 +1448,7 @@ - annotation: !!omap - chebi: CHEBI:57766 - kegg.compound: C01267 + - sbo: SBO:0000247 - !!omap - id: s_0208 - name: 3-aminopropanal @@ -1312,6 +1458,7 @@ - annotation: !!omap - chebi: CHEBI:58374 - kegg.compound: C02229 + - sbo: SBO:0000247 - !!omap - id: s_0209 - name: 3-dehydro-4-methylzymosterol @@ -1321,6 +1468,7 @@ - annotation: !!omap - chebi: CHEBI:50593 - kegg.compound: C15816 + - sbo: SBO:0000247 - !!omap - id: s_0210 - name: 3-dehydroquinate @@ -1330,6 +1478,7 @@ - annotation: !!omap - chebi: CHEBI:32364 - kegg.compound: C00944 + - sbo: SBO:0000247 - !!omap - id: s_0211 - name: 3-dehydroshikimate @@ -1339,6 +1488,7 @@ - annotation: !!omap - chebi: CHEBI:16630 - kegg.compound: C02637 + - sbo: SBO:0000247 - !!omap - id: s_0212 - name: 3-hexaprenyl-4,5-dihydroxybenzoic acid @@ -1348,6 +1498,7 @@ - annotation: !!omap - chebi: CHEBI:58373 - kegg.compound: C05200 + - sbo: SBO:0000247 - !!omap - id: s_0213 - name: 3-hexaprenyl-4,5-dihydroxybenzoic acid @@ -1357,6 +1508,7 @@ - annotation: !!omap - chebi: CHEBI:58373 - kegg.compound: C05200 + - sbo: SBO:0000247 - !!omap - id: s_0214 - name: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid @@ -1366,6 +1518,7 @@ - annotation: !!omap - chebi: CHEBI:57916 - kegg.compound: C05313 + - sbo: SBO:0000247 - !!omap - id: s_0215 - name: 3-hexaprenyl-4-hydroxybenzoic acid @@ -1375,6 +1528,7 @@ - annotation: !!omap - chebi: CHEBI:31116 - kegg.compound: C13425 + - sbo: SBO:0000247 - !!omap - id: s_0216 - name: 3-hexaprenyl-4-hydroxybenzoic acid @@ -1384,6 +1538,7 @@ - annotation: !!omap - chebi: CHEBI:31116 - kegg.compound: C13425 + - sbo: SBO:0000247 - !!omap - id: s_0217 - name: 3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoate @@ -1392,6 +1547,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:52960 + - sbo: SBO:0000247 - !!omap - id: s_0218 - name: 3-hydroxy-3-methylglutaryl-CoA @@ -1401,6 +1557,7 @@ - annotation: !!omap - chebi: CHEBI:11814 - kegg.compound: C00356 + - sbo: SBO:0000247 - !!omap - id: s_0221 - name: 3-hydroxy-3-methylglutaryl-CoA @@ -1410,6 +1567,7 @@ - annotation: !!omap - chebi: CHEBI:11814 - kegg.compound: C00356 + - sbo: SBO:0000247 - !!omap - id: s_0222 - name: 3-hydroxy-L-kynurenine @@ -1419,6 +1577,7 @@ - annotation: !!omap - chebi: CHEBI:17380 - kegg.compound: C03227 + - sbo: SBO:0000247 - !!omap - id: s_0224 - name: 3-hydroxyanthranilate @@ -1428,6 +1587,7 @@ - annotation: !!omap - chebi: CHEBI:36559 - kegg.compound: C00632 + - sbo: SBO:0000247 - !!omap - id: s_0229 - name: 3-hydroxyoctadecanoyl-CoA @@ -1437,6 +1597,7 @@ - annotation: !!omap - chebi: CHEBI:50583 - kegg.compound: C16217 + - sbo: SBO:0000247 - !!omap - id: s_0231 - name: 3-ketosphinganine @@ -1446,6 +1607,7 @@ - annotation: !!omap - chebi: CHEBI:58299 - kegg.compound: C02934 + - sbo: SBO:0000247 - !!omap - id: s_0232 - name: 3-methyl-2-oxobutanoate @@ -1455,6 +1617,7 @@ - annotation: !!omap - chebi: CHEBI:11851 - kegg.compound: C00141 + - sbo: SBO:0000247 - !!omap - id: s_0233 - name: 3-methyl-2-oxobutanoate @@ -1464,6 +1627,7 @@ - annotation: !!omap - chebi: CHEBI:11851 - kegg.compound: C00141 + - sbo: SBO:0000247 - !!omap - id: s_0234 - name: 3-methylbutanal @@ -1473,6 +1637,7 @@ - annotation: !!omap - chebi: CHEBI:16638 - kegg.compound: C07329 + - sbo: SBO:0000247 - !!omap - id: s_0235 - name: 3-methylbutanal @@ -1482,6 +1647,7 @@ - annotation: !!omap - chebi: CHEBI:16638 - kegg.compound: C07329 + - sbo: SBO:0000247 - !!omap - id: s_0236 - name: 3-methylbutanal @@ -1491,6 +1657,7 @@ - annotation: !!omap - chebi: CHEBI:16638 - kegg.compound: C07329 + - sbo: SBO:0000247 - !!omap - id: s_0239 - name: 3-oxodecanoyl-CoA @@ -1500,6 +1667,7 @@ - annotation: !!omap - chebi: CHEBI:28528 - kegg.compound: C05265 + - sbo: SBO:0000247 - !!omap - id: s_0243 - name: 3-oxohexacosanoyl-CoA @@ -1508,6 +1676,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52977 + - sbo: SBO:0000247 - !!omap - id: s_0247 - name: 3-oxolauroyl-CoA @@ -1517,6 +1686,7 @@ - annotation: !!omap - chebi: CHEBI:27868 - kegg.compound: C05263 + - sbo: SBO:0000247 - !!omap - id: s_0250 - name: 3-oxooctadecanoyl-CoA @@ -1526,6 +1696,7 @@ - annotation: !!omap - chebi: CHEBI:50571 - kegg.compound: C16216 + - sbo: SBO:0000247 - !!omap - id: s_0253 - name: 3-oxopalmitoyl-CoA @@ -1535,6 +1706,7 @@ - annotation: !!omap - chebi: CHEBI:57349 - kegg.compound: C05259 + - sbo: SBO:0000247 - !!omap - id: s_0257 - name: 3-oxotetradecanoyl-CoA @@ -1544,6 +1716,7 @@ - annotation: !!omap - chebi: CHEBI:28726 - kegg.compound: C05261 + - sbo: SBO:0000247 - !!omap - id: s_0258 - name: 3-phospho-hydroxypyruvate @@ -1553,6 +1726,7 @@ - annotation: !!omap - chebi: CHEBI:18110 - kegg.compound: C03232 + - sbo: SBO:0000247 - !!omap - id: s_0259 - name: 3-phospho-serine @@ -1562,6 +1736,7 @@ - annotation: !!omap - chebi: CHEBI:57524 - kegg.compound: C01005 + - sbo: SBO:0000247 - !!omap - id: s_0260 - name: 3-phosphonato-D-glycerate(3-) @@ -1571,6 +1746,7 @@ - annotation: !!omap - chebi: CHEBI:58272 - kegg.compound: C00197 + - sbo: SBO:0000247 - !!omap - id: s_0261 - name: 3-phosphoshikimic acid @@ -1580,6 +1756,7 @@ - annotation: !!omap - chebi: CHEBI:145989 - kegg.compound: C03175 + - sbo: SBO:0000247 - !!omap - id: s_0262 - name: 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol @@ -1589,6 +1766,7 @@ - annotation: !!omap - chebi: CHEBI:17813 - kegg.compound: C11455 + - sbo: SBO:0000247 - !!omap - id: s_0263 - name: 4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate @@ -1597,6 +1775,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53066 + - sbo: SBO:0000247 - !!omap - id: s_0264 - name: 4-(phosphonooxy)-L-threonine @@ -1606,6 +1785,7 @@ - annotation: !!omap - chebi: CHEBI:58452 - kegg.compound: C06055 + - sbo: SBO:0000247 - !!omap - id: s_0267 - name: 4-amino-2-methyl-5-diphosphomethylpyrimidine @@ -1615,6 +1795,7 @@ - annotation: !!omap - chebi: CHEBI:57841 - kegg.compound: C04752 + - sbo: SBO:0000247 - !!omap - id: s_0268 - name: 4-amino-2-methyl-5-phosphomethylpyrimidine @@ -1624,6 +1805,7 @@ - annotation: !!omap - chebi: CHEBI:58354 - kegg.compound: C04556 + - sbo: SBO:0000247 - !!omap - id: s_0269 - name: 4-amino-4-deoxychorismate @@ -1633,6 +1815,7 @@ - annotation: !!omap - chebi: CHEBI:35181 - kegg.compound: C11355 + - sbo: SBO:0000247 - !!omap - id: s_0270 - name: 4-amino-5-hydroxymethyl-2-methylpyrimidine @@ -1642,6 +1825,7 @@ - annotation: !!omap - chebi: CHEBI:16892 - kegg.compound: C01279 + - sbo: SBO:0000247 - !!omap - id: s_0271 - name: 4-aminobenzoate @@ -1651,6 +1835,7 @@ - annotation: !!omap - chebi: CHEBI:17836 - kegg.compound: C00568 + - sbo: SBO:0000247 - !!omap - id: s_0272 - name: 4-aminobenzoate @@ -1660,6 +1845,7 @@ - annotation: !!omap - chebi: CHEBI:17836 - kegg.compound: C00568 + - sbo: SBO:0000247 - !!omap - id: s_0273 - name: 4-aminobenzoate @@ -1669,6 +1855,7 @@ - annotation: !!omap - chebi: CHEBI:17836 - kegg.compound: C00568 + - sbo: SBO:0000247 - !!omap - id: s_0274 - name: 4-aminobutanal @@ -1678,6 +1865,7 @@ - annotation: !!omap - chebi: CHEBI:58264 - kegg.compound: C00555 + - sbo: SBO:0000247 - !!omap - id: s_0275 - name: 4-aminobutanal @@ -1687,6 +1875,7 @@ - annotation: !!omap - chebi: CHEBI:58264 - kegg.compound: C00555 + - sbo: SBO:0000247 - !!omap - id: s_0279 - name: 4-diphospho-1D-myo-inositol pentakisphosphate @@ -1695,6 +1884,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53064 + - sbo: SBO:0000247 - !!omap - id: s_0280 - name: 4-guanidinobutanamide @@ -1704,6 +1894,7 @@ - annotation: !!omap - chebi: CHEBI:58365 - kegg.compound: C03078 + - sbo: SBO:0000247 - !!omap - id: s_0281 - name: 4-guanidinobutanoic acid @@ -1713,6 +1904,7 @@ - annotation: !!omap - chebi: CHEBI:15728 - kegg.compound: C01035 + - sbo: SBO:0000247 - !!omap - id: s_0282 - name: 4-hydroxy-2-oxoglutarate @@ -1722,6 +1914,7 @@ - annotation: !!omap - chebi: CHEBI:17742 - kegg.compound: C01127 + - sbo: SBO:0000247 - !!omap - id: s_0283 - name: 4-hydroxy-2-oxoglutarate @@ -1731,6 +1924,7 @@ - annotation: !!omap - chebi: CHEBI:17742 - kegg.compound: C01127 + - sbo: SBO:0000247 - !!omap - id: s_0284 - name: 4-hydroxy-2-oxoglutarate @@ -1740,6 +1934,7 @@ - annotation: !!omap - chebi: CHEBI:17742 - kegg.compound: C01127 + - sbo: SBO:0000247 - !!omap - id: s_0285 - name: 4-hydroxy-L-threonine @@ -1749,6 +1944,7 @@ - annotation: !!omap - chebi: CHEBI:28330 - kegg.compound: C06056 + - sbo: SBO:0000247 - !!omap - id: s_0286 - name: 4-hydroxybenzoate @@ -1758,6 +1954,7 @@ - annotation: !!omap - chebi: CHEBI:17879 - kegg.compound: C00156 + - sbo: SBO:0000247 - !!omap - id: s_0287 - name: 4-hydroxybenzoate @@ -1767,6 +1964,7 @@ - annotation: !!omap - chebi: CHEBI:17879 - kegg.compound: C00156 + - sbo: SBO:0000247 - !!omap - id: s_0290 - name: 4-hydroxybenzoyl-CoA @@ -1776,6 +1974,7 @@ - annotation: !!omap - chebi: CHEBI:57356 - kegg.compound: C02949 + - sbo: SBO:0000247 - !!omap - id: s_0291 - name: 4-methyl-2-oxopentanoate @@ -1785,6 +1984,7 @@ - annotation: !!omap - chebi: CHEBI:17865 - kegg.compound: C00233 + - sbo: SBO:0000247 - !!omap - id: s_0292 - name: 4-methyl-2-oxopentanoate @@ -1794,6 +1994,7 @@ - annotation: !!omap - chebi: CHEBI:17865 - kegg.compound: C00233 + - sbo: SBO:0000247 - !!omap - id: s_0293 - name: 4-methyl-5-(2-phosphonooxyethyl)thiazole @@ -1803,6 +2004,7 @@ - annotation: !!omap - chebi: CHEBI:58296 - kegg.compound: C04327 + - sbo: SBO:0000247 - !!omap - id: s_0294 - name: 4-methylthio-2-oxobutanoate @@ -1812,6 +2014,7 @@ - annotation: !!omap - chebi: CHEBI:16723 - kegg.compound: C01180 + - sbo: SBO:0000247 - !!omap - id: s_0295 - name: 4-phospho-L-aspartate @@ -1821,6 +2024,7 @@ - annotation: !!omap - chebi: CHEBI:30407 - kegg.compound: C03082 + - sbo: SBO:0000247 - !!omap - id: s_0296 - name: 4alpha-methylzymosterol @@ -1830,6 +2034,7 @@ - annotation: !!omap - chebi: CHEBI:1949 - kegg.compound: C05103 + - sbo: SBO:0000247 - !!omap - id: s_0297 - name: 4beta-methylzymosterol-4alpha-carboxylic acid @@ -1839,6 +2044,7 @@ - annotation: !!omap - chebi: CHEBI:50591 - kegg.compound: C15808 + - sbo: SBO:0000247 - !!omap - id: s_0298 - name: 5'-adenylyl sulfate @@ -1848,6 +2054,7 @@ - annotation: !!omap - chebi: CHEBI:58243 - kegg.compound: C00224 + - sbo: SBO:0000247 - !!omap - id: s_0299 - name: 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole @@ -1857,6 +2064,7 @@ - annotation: !!omap - chebi: CHEBI:58443 - kegg.compound: C04823 + - sbo: SBO:0000247 - !!omap - id: s_0300 - name: 5'-phosphoribosyl-5-aminoimidazole @@ -1866,6 +2074,7 @@ - annotation: !!omap - chebi: CHEBI:58592 - kegg.compound: C03373 + - sbo: SBO:0000247 - !!omap - id: s_0301 - name: 5'-phosphoribosyl-N-formylglycineamide @@ -1875,6 +2084,7 @@ - annotation: !!omap - chebi: CHEBI:58426 - kegg.compound: C04376 + - sbo: SBO:0000247 - !!omap - id: s_0302 - name: 5'-phosphoribosyl-N-formylglycineamidine @@ -1884,6 +2094,7 @@ - annotation: !!omap - chebi: CHEBI:58478 - kegg.compound: C04640 + - sbo: SBO:0000247 - !!omap - id: s_0303 - name: 5'-S-methyl-5'-thioadenosine @@ -1893,6 +2104,7 @@ - annotation: !!omap - chebi: CHEBI:17509 - kegg.compound: C00170 + - sbo: SBO:0000247 - !!omap - id: s_0304 - name: 5,10-methenyl-THF @@ -1902,6 +2114,7 @@ - annotation: !!omap - chebi: CHEBI:57455 - kegg.compound: C00445 + - sbo: SBO:0000247 - !!omap - id: s_0305 - name: 5,10-methenyl-THF @@ -1911,6 +2124,7 @@ - annotation: !!omap - chebi: CHEBI:57455 - kegg.compound: C00445 + - sbo: SBO:0000247 - !!omap - id: s_0306 - name: 5,10-methylenetetrahydrofolate @@ -1920,6 +2134,7 @@ - annotation: !!omap - chebi: CHEBI:12071 - kegg.compound: C00143 + - sbo: SBO:0000247 - !!omap - id: s_0307 - name: 5,10-methylenetetrahydrofolate @@ -1929,6 +2144,7 @@ - annotation: !!omap - chebi: CHEBI:12071 - kegg.compound: C00143 + - sbo: SBO:0000247 - !!omap - id: s_0308 - name: 5,6,7,8-tetrahydrofolyl-L-glutamic acid @@ -1938,6 +2154,7 @@ - annotation: !!omap - chebi: CHEBI:27650 - kegg.compound: C09332 + - sbo: SBO:0000247 - !!omap - id: s_0309 - name: 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate @@ -1946,6 +2163,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52965 + - sbo: SBO:0000247 - !!omap - id: s_0310 - name: 5-(2-hydroxyethyl)-4-methylthiazole @@ -1955,6 +2173,7 @@ - annotation: !!omap - chebi: CHEBI:17957 - kegg.compound: C04294 + - sbo: SBO:0000247 - !!omap - id: s_0311 - name: 5-(methylsulfanyl)-2,3-dioxopentyl phosphate @@ -1964,6 +2183,7 @@ - annotation: !!omap - chebi: CHEBI:58828 - kegg.compound: C15650 + - sbo: SBO:0000247 - !!omap - id: s_0312 - name: 5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide @@ -1973,6 +2193,7 @@ - annotation: !!omap - chebi: CHEBI:58525 - kegg.compound: C04916 + - sbo: SBO:0000247 - !!omap - id: s_0313 - name: 5-amino-6-(5-phosphoribitylamino)uracil @@ -1982,6 +2203,7 @@ - annotation: !!omap - chebi: CHEBI:58421 - kegg.compound: C04454 + - sbo: SBO:0000247 - !!omap - id: s_0314 - name: 5-amino-6-(D-ribitylamino)uracil @@ -1991,6 +2213,7 @@ - annotation: !!omap - chebi: CHEBI:15934 - kegg.compound: C04732 + - sbo: SBO:0000247 - !!omap - id: s_0315 - name: 5-aminolevulinate @@ -2000,6 +2223,7 @@ - annotation: !!omap - chebi: CHEBI:17549 - kegg.compound: C00430 + - sbo: SBO:0000247 - !!omap - id: s_0316 - name: 5-aminolevulinate @@ -2009,6 +2233,7 @@ - annotation: !!omap - chebi: CHEBI:17549 - kegg.compound: C00430 + - sbo: SBO:0000247 - !!omap - id: s_0317 - name: 5-aminolevulinate @@ -2018,6 +2243,7 @@ - annotation: !!omap - chebi: CHEBI:17549 - kegg.compound: C00430 + - sbo: SBO:0000247 - !!omap - id: s_0318 - name: 5-diphospho-1D-myo-inositol pentakisphosphate @@ -2027,6 +2253,7 @@ - annotation: !!omap - chebi: CHEBI:58628 - kegg.compound: C11526 + - sbo: SBO:0000247 - !!omap - id: s_0319 - name: 5-formyltetrahydrofolic acid @@ -2036,6 +2263,7 @@ - annotation: !!omap - chebi: CHEBI:57457 - kegg.compound: C03479 + - sbo: SBO:0000247 - !!omap - id: s_0320 - name: 5-formyltetrahydrofolic acid @@ -2045,6 +2273,7 @@ - annotation: !!omap - chebi: CHEBI:57457 - kegg.compound: C03479 + - sbo: SBO:0000247 - !!omap - id: s_0321 - name: 5-formyltetrahydrofolic acid @@ -2054,6 +2283,7 @@ - annotation: !!omap - chebi: CHEBI:57457 - kegg.compound: C03479 + - sbo: SBO:0000247 - !!omap - id: s_0322 - name: 5-methyltetrahydrofolate @@ -2063,6 +2293,7 @@ - annotation: !!omap - chebi: CHEBI:18608 - kegg.compound: C00440 + - sbo: SBO:0000247 - !!omap - id: s_0323 - name: 5-methyltetrahydropteroyltri-L-glutamic acid @@ -2072,6 +2303,7 @@ - annotation: !!omap - chebi: CHEBI:58207 - kegg.compound: C04489 + - sbo: SBO:0000247 - !!omap - id: s_0324 - name: 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid @@ -2081,6 +2313,7 @@ - annotation: !!omap - chebi: CHEBI:57701 - kegg.compound: C01269 + - sbo: SBO:0000247 - !!omap - id: s_0325 - name: 5-phospho-ribosyl-glycineamide @@ -2090,6 +2323,7 @@ - annotation: !!omap - chebi: CHEBI:58457 - kegg.compound: C03838 + - sbo: SBO:0000247 - !!omap - id: s_0326 - name: 5-phosphoribosyl-ATP @@ -2099,6 +2333,7 @@ - annotation: !!omap - chebi: CHEBI:58424 - kegg.compound: C02739 + - sbo: SBO:0000247 - !!omap - id: s_0327 - name: 5-phosphoribosylamine @@ -2108,6 +2343,7 @@ - annotation: !!omap - chebi: CHEBI:58681 - kegg.compound: C03090 + - sbo: SBO:0000247 - !!omap - id: s_0328 - name: 6,7-dimethyl-8-(1-D-ribityl)lumazine @@ -2117,6 +2353,7 @@ - annotation: !!omap - chebi: CHEBI:58201 - kegg.compound: C04332 + - sbo: SBO:0000247 - !!omap - id: s_0329 - name: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol @@ -2126,6 +2363,7 @@ - annotation: !!omap - chebi: CHEBI:17049 - kegg.compound: C04248 + - sbo: SBO:0000247 - !!omap - id: s_0330 - name: 6-(alpha-D-glucosaminyl)-O-acyl-1-phosphatidyl-1D-myo-inositol @@ -2133,6 +2371,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53055 + - sbo: SBO:0000247 - !!omap - id: s_0331 - name: 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol @@ -2142,6 +2381,7 @@ - annotation: !!omap - chebi: CHEBI:57265 - kegg.compound: C01288 + - sbo: SBO:0000247 - !!omap - id: s_0332 - name: 6-[6-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-2-(2-aminoethylphosphoryl)-alpha-mannosyl-(1->6)-alpha-2-(2-aminoethylphosphoryl)mannosyl-(1->4)-alpha-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol @@ -2150,6 +2390,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53060 + - sbo: SBO:0000247 - !!omap - id: s_0333 - name: 6-diphospho-1D-myo-inositol pentakisphosphate @@ -2158,6 +2399,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53065 + - sbo: SBO:0000247 - !!omap - id: s_0334 - name: 6-O-[alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-O-acyl-1-phosphatidyl-1D-myo-inositol @@ -2165,6 +2407,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53056 + - sbo: SBO:0000247 - !!omap - id: s_0335 - name: 6-O-phosphono-D-glucono-1,5-lactone @@ -2174,6 +2417,7 @@ - annotation: !!omap - chebi: CHEBI:57955 - kegg.compound: C01236 + - sbo: SBO:0000247 - !!omap - id: s_0337 - name: 6-O-{2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol @@ -2181,6 +2425,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53057 + - sbo: SBO:0000247 - !!omap - id: s_0338 - name: 6-O-{alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol @@ -2188,6 +2433,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53059 + - sbo: SBO:0000247 - !!omap - id: s_0339 - name: 6-O-{alpha-D-mannosyl-(1->6)-2-O-[(2-aminoethyl)phosphoryl]-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl}-O-acyl-1-phosphatidyl-1D-myo-inositol @@ -2195,6 +2441,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53058 + - sbo: SBO:0000247 - !!omap - id: s_0340 - name: 6-phospho-D-gluconate @@ -2204,6 +2451,7 @@ - annotation: !!omap - chebi: CHEBI:58759 - kegg.compound: C00345 + - sbo: SBO:0000247 - !!omap - id: s_0341 - name: 7,8-diaminononanoate @@ -2213,6 +2461,7 @@ - annotation: !!omap - chebi: CHEBI:17830 - kegg.compound: C01037 + - sbo: SBO:0000247 - !!omap - id: s_0342 - name: 7,8-diaminononanoate @@ -2222,6 +2471,7 @@ - annotation: !!omap - chebi: CHEBI:17830 - kegg.compound: C01037 + - sbo: SBO:0000247 - !!omap - id: s_0343 - name: 7,8-dihydroneopterin @@ -2231,6 +2481,7 @@ - annotation: !!omap - chebi: CHEBI:17001 - kegg.compound: C04874 + - sbo: SBO:0000247 - !!omap - id: s_0344 - name: 7,8-dihydroneopterin @@ -2240,6 +2491,7 @@ - annotation: !!omap - chebi: CHEBI:17001 - kegg.compound: C04874 + - sbo: SBO:0000247 - !!omap - id: s_0345 - name: 7,8-dihydroneopterin 3'-phosphate @@ -2249,6 +2501,7 @@ - annotation: !!omap - chebi: CHEBI:58762 - kegg.compound: C05925 + - sbo: SBO:0000247 - !!omap - id: s_0346 - name: 7,8-dihydroneopterin 3'-triphosphate @@ -2258,6 +2511,7 @@ - annotation: !!omap - chebi: CHEBI:58462 - kegg.compound: C04895 + - sbo: SBO:0000247 - !!omap - id: s_0347 - name: 7,8-dihydropteroate @@ -2267,6 +2521,7 @@ - annotation: !!omap - chebi: CHEBI:17839 - kegg.compound: C00921 + - sbo: SBO:0000247 - !!omap - id: s_0348 - name: 7,8-dihydropteroate @@ -2276,6 +2531,7 @@ - annotation: !!omap - chebi: CHEBI:17839 - kegg.compound: C00921 + - sbo: SBO:0000247 - !!omap - id: s_0349 - name: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid @@ -2285,6 +2541,7 @@ - annotation: !!omap - chebi: CHEBI:58394 - kegg.compound: C04691 + - sbo: SBO:0000247 - !!omap - id: s_0350 - name: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid @@ -2294,6 +2551,7 @@ - annotation: !!omap - chebi: CHEBI:58394 - kegg.compound: C04691 + - sbo: SBO:0000247 - !!omap - id: s_0352 - name: 8-amino-7-oxononanoate @@ -2303,6 +2561,7 @@ - annotation: !!omap - chebi: CHEBI:15830 - kegg.compound: C01092 + - sbo: SBO:0000247 - !!omap - id: s_0354 - name: 8-amino-7-oxononanoate @@ -2312,6 +2571,7 @@ - annotation: !!omap - chebi: CHEBI:15830 - kegg.compound: C01092 + - sbo: SBO:0000247 - !!omap - id: s_0357 - name: 9H-xanthine @@ -2321,6 +2581,7 @@ - annotation: !!omap - chebi: CHEBI:17712 - kegg.compound: C00385 + - sbo: SBO:0000247 - !!omap - id: s_0358 - name: 9H-xanthine @@ -2330,6 +2591,7 @@ - annotation: !!omap - chebi: CHEBI:17712 - kegg.compound: C00385 + - sbo: SBO:0000247 - !!omap - id: s_0359 - name: acetaldehyde @@ -2339,6 +2601,7 @@ - annotation: !!omap - chebi: CHEBI:15343 - kegg.compound: C00084 + - sbo: SBO:0000247 - !!omap - id: s_0360 - name: acetaldehyde @@ -2348,6 +2611,7 @@ - annotation: !!omap - chebi: CHEBI:15343 - kegg.compound: C00084 + - sbo: SBO:0000247 - !!omap - id: s_0361 - name: acetaldehyde @@ -2357,6 +2621,7 @@ - annotation: !!omap - chebi: CHEBI:15343 - kegg.compound: C00084 + - sbo: SBO:0000247 - !!omap - id: s_0362 - name: acetate @@ -2366,6 +2631,7 @@ - annotation: !!omap - chebi: CHEBI:30089 - kegg.compound: C00033 + - sbo: SBO:0000247 - !!omap - id: s_0363 - name: acetate @@ -2375,6 +2641,7 @@ - annotation: !!omap - chebi: CHEBI:30089 - kegg.compound: C00033 + - sbo: SBO:0000247 - !!omap - id: s_0364 - name: acetate @@ -2384,6 +2651,7 @@ - annotation: !!omap - chebi: CHEBI:30089 - kegg.compound: C00033 + - sbo: SBO:0000247 - !!omap - id: s_0365 - name: acetate @@ -2393,6 +2661,7 @@ - annotation: !!omap - chebi: CHEBI:30089 - kegg.compound: C00033 + - sbo: SBO:0000247 - !!omap - id: s_0366 - name: acetate @@ -2402,6 +2671,7 @@ - annotation: !!omap - chebi: CHEBI:30089 - kegg.compound: C00033 + - sbo: SBO:0000247 - !!omap - id: s_0367 - name: acetoacetyl-CoA @@ -2411,6 +2681,7 @@ - annotation: !!omap - chebi: CHEBI:57286 - kegg.compound: C00332 + - sbo: SBO:0000247 - !!omap - id: s_0370 - name: acetoacetyl-CoA @@ -2420,6 +2691,7 @@ - annotation: !!omap - chebi: CHEBI:57286 - kegg.compound: C00332 + - sbo: SBO:0000247 - !!omap - id: s_0372 - name: acetyl-ACP @@ -2429,6 +2701,7 @@ - annotation: !!omap - chebi: CHEBI:17093 - kegg.compound: C03939 + - sbo: SBO:0000247 - !!omap - id: s_0373 - name: acetyl-CoA @@ -2438,6 +2711,7 @@ - annotation: !!omap - chebi: CHEBI:57288 - kegg.compound: C00024 + - sbo: SBO:0000247 - !!omap - id: s_0376 - name: acetyl-CoA @@ -2447,6 +2721,7 @@ - annotation: !!omap - chebi: CHEBI:57288 - kegg.compound: C00024 + - sbo: SBO:0000247 - !!omap - id: s_0377 - name: acetyl-CoA @@ -2456,6 +2731,7 @@ - annotation: !!omap - chebi: CHEBI:57288 - kegg.compound: C00024 + - sbo: SBO:0000247 - !!omap - id: s_0378 - name: acetyl-CoA @@ -2465,6 +2741,7 @@ - annotation: !!omap - chebi: CHEBI:57288 - kegg.compound: C00024 + - sbo: SBO:0000247 - !!omap - id: s_0383 - name: adenine @@ -2474,6 +2751,7 @@ - annotation: !!omap - chebi: CHEBI:16708 - kegg.compound: C00147 + - sbo: SBO:0000247 - !!omap - id: s_0384 - name: adenine @@ -2483,6 +2761,7 @@ - annotation: !!omap - chebi: CHEBI:16708 - kegg.compound: C00147 + - sbo: SBO:0000247 - !!omap - id: s_0385 - name: adenine @@ -2492,6 +2771,7 @@ - annotation: !!omap - chebi: CHEBI:16708 - kegg.compound: C00147 + - sbo: SBO:0000247 - !!omap - id: s_0386 - name: adenosine @@ -2501,6 +2781,7 @@ - annotation: !!omap - chebi: CHEBI:16335 - kegg.compound: C00212 + - sbo: SBO:0000247 - !!omap - id: s_0387 - name: adenosine @@ -2510,6 +2791,7 @@ - annotation: !!omap - chebi: CHEBI:16335 - kegg.compound: C00212 + - sbo: SBO:0000247 - !!omap - id: s_0389 - name: adenosine 2'-phosphate @@ -2519,6 +2801,7 @@ - annotation: !!omap - chebi: CHEBI:28223 - kegg.compound: C00946 + - sbo: SBO:0000247 - !!omap - id: s_0390 - name: adenosine 3',5'-bismonophosphate @@ -2528,6 +2811,7 @@ - annotation: !!omap - chebi: CHEBI:58343 - kegg.compound: C00054 + - sbo: SBO:0000247 - !!omap - id: s_0391 - name: adenosine 3',5'-bismonophosphate @@ -2537,6 +2821,7 @@ - annotation: !!omap - chebi: CHEBI:58343 - kegg.compound: C00054 + - sbo: SBO:0000247 - !!omap - id: s_0392 - name: adenosine 3',5'-bismonophosphate @@ -2546,6 +2831,7 @@ - annotation: !!omap - chebi: CHEBI:58343 - kegg.compound: C00054 + - sbo: SBO:0000247 - !!omap - id: s_0393 - name: adenylo-succinate @@ -2555,6 +2841,7 @@ - annotation: !!omap - chebi: CHEBI:57567 - kegg.compound: C03794 + - sbo: SBO:0000247 - !!omap - id: s_0394 - name: ADP @@ -2564,6 +2851,7 @@ - annotation: !!omap - chebi: CHEBI:456216 - kegg.compound: C00008 + - sbo: SBO:0000247 - !!omap - id: s_0395 - name: ADP @@ -2573,6 +2861,7 @@ - annotation: !!omap - chebi: CHEBI:456216 - kegg.compound: C00008 + - sbo: SBO:0000247 - !!omap - id: s_0397 - name: ADP @@ -2582,6 +2871,7 @@ - annotation: !!omap - chebi: CHEBI:456216 - kegg.compound: C00008 + - sbo: SBO:0000247 - !!omap - id: s_0398 - name: ADP @@ -2591,6 +2881,7 @@ - annotation: !!omap - chebi: CHEBI:456216 - kegg.compound: C00008 + - sbo: SBO:0000247 - !!omap - id: s_0399 - name: ADP @@ -2600,6 +2891,7 @@ - annotation: !!omap - chebi: CHEBI:456216 - kegg.compound: C00008 + - sbo: SBO:0000247 - !!omap - id: s_0402 - name: ADP-ribose @@ -2609,6 +2901,7 @@ - annotation: !!omap - chebi: CHEBI:57967 - kegg.compound: C00301 + - sbo: SBO:0000247 - !!omap - id: s_0403 - name: AICAR @@ -2618,6 +2911,7 @@ - annotation: !!omap - chebi: CHEBI:58475 - kegg.compound: C04677 + - sbo: SBO:0000247 - !!omap - id: s_0404 - name: Ala-tRNA(Ala) @@ -2627,6 +2921,7 @@ - annotation: !!omap - chebi: CHEBI:17732 - kegg.compound: C00886 + - sbo: SBO:0000247 - !!omap - id: s_0405 - name: allantoate @@ -2636,6 +2931,7 @@ - annotation: !!omap - chebi: CHEBI:17536 - kegg.compound: C00499 + - sbo: SBO:0000247 - !!omap - id: s_0406 - name: allantoate @@ -2645,6 +2941,7 @@ - annotation: !!omap - chebi: CHEBI:17536 - kegg.compound: C00499 + - sbo: SBO:0000247 - !!omap - id: s_0407 - name: allantoin @@ -2654,6 +2951,7 @@ - annotation: !!omap - chebi: CHEBI:15676 - kegg.compound: C01551 + - sbo: SBO:0000247 - !!omap - id: s_0408 - name: allantoin @@ -2663,6 +2961,7 @@ - annotation: !!omap - chebi: CHEBI:15676 - kegg.compound: C01551 + - sbo: SBO:0000247 - !!omap - id: s_0409 - name: alpha,alpha-trehalose 6-phosphate @@ -2672,6 +2971,7 @@ - annotation: !!omap - chebi: CHEBI:58429 - kegg.compound: C00689 + - sbo: SBO:0000247 - !!omap - id: s_0410 - name: alpha-D-galactose 1-phosphate @@ -2681,6 +2981,7 @@ - annotation: !!omap - chebi: CHEBI:58336 - kegg.compound: C00446 + - sbo: SBO:0000247 - !!omap - id: s_0411 - name: alpha-D-glucosamine 1-phosphate @@ -2690,6 +2991,7 @@ - annotation: !!omap - chebi: CHEBI:58516 - kegg.compound: C06156 + - sbo: SBO:0000247 - !!omap - id: s_0412 - name: alpha-D-glucosamine 6-phosphate @@ -2699,6 +3001,7 @@ - annotation: !!omap - chebi: CHEBI:15873 - kegg.compound: C00352 + - sbo: SBO:0000247 - !!omap - id: s_0413 - name: alpha-D-glucosamine 6-phosphate @@ -2708,6 +3011,7 @@ - annotation: !!omap - chebi: CHEBI:15873 - kegg.compound: C00352 + - sbo: SBO:0000247 - !!omap - id: s_0414 - name: alpha-D-mannosyl-beta-D-mannosyldiacetylchitobiosyldiphosphodolichol @@ -2717,6 +3021,7 @@ - annotation: !!omap - chebi: CHEBI:28067 - kegg.compound: C05861 + - sbo: SBO:0000247 - !!omap - id: s_0415 - name: alpha-D-ribose 1-phosphate(2-) @@ -2726,6 +3031,7 @@ - annotation: !!omap - chebi: CHEBI:57720 - kegg.compound: C00620 + - sbo: SBO:0000247 - !!omap - id: s_0416 - name: alpha-D-ribose 1-phosphate(2-) @@ -2735,6 +3041,7 @@ - annotation: !!omap - chebi: CHEBI:57720 - kegg.compound: C00620 + - sbo: SBO:0000247 - !!omap - id: s_0417 - name: aminoacetaldehyde @@ -2744,6 +3051,7 @@ - annotation: !!omap - chebi: CHEBI:58213 - kegg.compound: C06735 + - sbo: SBO:0000247 - !!omap - id: s_0418 - name: aminoacetone @@ -2753,6 +3061,7 @@ - annotation: !!omap - chebi: CHEBI:58320 - kegg.compound: C01888 + - sbo: SBO:0000247 - !!omap - id: s_0419 - name: ammonium @@ -2762,6 +3071,7 @@ - annotation: !!omap - chebi: CHEBI:28938 - kegg.compound: C01342 + - sbo: SBO:0000247 - !!omap - id: s_0420 - name: ammonium @@ -2771,6 +3081,7 @@ - annotation: !!omap - chebi: CHEBI:28938 - kegg.compound: C01342 + - sbo: SBO:0000247 - !!omap - id: s_0421 - name: ammonium @@ -2780,6 +3091,7 @@ - annotation: !!omap - chebi: CHEBI:28938 - kegg.compound: C01342 + - sbo: SBO:0000247 - !!omap - id: s_0423 - name: AMP @@ -2789,6 +3101,7 @@ - annotation: !!omap - chebi: CHEBI:456215 - kegg.compound: C00020 + - sbo: SBO:0000247 - !!omap - id: s_0424 - name: AMP @@ -2798,6 +3111,7 @@ - annotation: !!omap - chebi: CHEBI:456215 - kegg.compound: C00020 + - sbo: SBO:0000247 - !!omap - id: s_0425 - name: AMP @@ -2807,6 +3121,7 @@ - annotation: !!omap - chebi: CHEBI:456215 - kegg.compound: C00020 + - sbo: SBO:0000247 - !!omap - id: s_0426 - name: AMP @@ -2816,6 +3131,7 @@ - annotation: !!omap - chebi: CHEBI:456215 - kegg.compound: C00020 + - sbo: SBO:0000247 - !!omap - id: s_0427 - name: anthranilate @@ -2825,6 +3141,7 @@ - annotation: !!omap - chebi: CHEBI:16567 - kegg.compound: C00108 + - sbo: SBO:0000247 - !!omap - id: s_0428 - name: Arg-tRNA(Arg) @@ -2834,6 +3151,7 @@ - annotation: !!omap - chebi: CHEBI:18366 - kegg.compound: C02163 + - sbo: SBO:0000247 - !!omap - id: s_0429 - name: Arg-tRNA(Arg) @@ -2843,6 +3161,7 @@ - annotation: !!omap - chebi: CHEBI:18366 - kegg.compound: C02163 + - sbo: SBO:0000247 - !!omap - id: s_0430 - name: Asn-tRNA(Asn) @@ -2852,6 +3171,7 @@ - annotation: !!omap - chebi: CHEBI:29265 - kegg.compound: C03402 + - sbo: SBO:0000247 - !!omap - id: s_0431 - name: Asn-tRNA(Asn) @@ -2861,6 +3181,7 @@ - annotation: !!omap - chebi: CHEBI:29265 - kegg.compound: C03402 + - sbo: SBO:0000247 - !!omap - id: s_0432 - name: Asp-tRNA(Asp) @@ -2870,6 +3191,7 @@ - annotation: !!omap - chebi: CHEBI:29158 - kegg.compound: C02984 + - sbo: SBO:0000247 - !!omap - id: s_0433 - name: Asp-tRNA(Asp) @@ -2879,6 +3201,7 @@ - annotation: !!omap - chebi: CHEBI:29158 - kegg.compound: C02984 + - sbo: SBO:0000247 - !!omap - id: s_0434 - name: ATP @@ -2888,6 +3211,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_0435 - name: ATP @@ -2897,6 +3221,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_0437 - name: ATP @@ -2906,6 +3231,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_0438 - name: ATP @@ -2915,6 +3241,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_0439 - name: ATP @@ -2924,6 +3251,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_0441 - name: beta-alanine @@ -2933,6 +3261,7 @@ - annotation: !!omap - chebi: CHEBI:16958 - kegg.compound: C00099 + - sbo: SBO:0000247 - !!omap - id: s_0442 - name: beta-D-fructose 2,6-bisphosphate @@ -2942,6 +3271,7 @@ - annotation: !!omap - chebi: CHEBI:58579 - kegg.compound: C00665 + - sbo: SBO:0000247 - !!omap - id: s_0443 - name: beta-D-mannosyldiacetylchitobiosyldiphosphodolichol @@ -2951,6 +3281,7 @@ - annotation: !!omap - chebi: CHEBI:18396 - kegg.compound: C05860 + - sbo: SBO:0000247 - !!omap - id: s_0444 - name: beta-D-mannosyldiacetylchitobiosyldiphosphodolichol @@ -2960,6 +3291,7 @@ - annotation: !!omap - chebi: CHEBI:18396 - kegg.compound: C05860 + - sbo: SBO:0000247 - !!omap - id: s_0445 - name: bicarbonate @@ -2969,6 +3301,7 @@ - annotation: !!omap - chebi: CHEBI:17544 - kegg.compound: C00288 + - sbo: SBO:0000247 - !!omap - id: s_0446 - name: bicarbonate @@ -2978,6 +3311,7 @@ - annotation: !!omap - chebi: CHEBI:17544 - kegg.compound: C00288 + - sbo: SBO:0000247 - !!omap - id: s_0447 - name: bicarbonate @@ -2987,6 +3321,7 @@ - annotation: !!omap - chebi: CHEBI:17544 - kegg.compound: C00288 + - sbo: SBO:0000247 - !!omap - id: s_0448 - name: bicarbonate @@ -2996,11 +3331,14 @@ - annotation: !!omap - chebi: CHEBI:17544 - kegg.compound: C00288 + - sbo: SBO:0000247 - !!omap - id: s_0450 - name: biomass - compartment: c - charge: 0 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_0451 - name: biotin @@ -3010,6 +3348,7 @@ - annotation: !!omap - chebi: CHEBI:57586 - kegg.compound: C00120 + - sbo: SBO:0000247 - !!omap - id: s_0452 - name: biotin @@ -3019,6 +3358,7 @@ - annotation: !!omap - chebi: CHEBI:57586 - kegg.compound: C00120 + - sbo: SBO:0000247 - !!omap - id: s_0453 - name: biotinyl-5'-AMP @@ -3028,6 +3368,7 @@ - annotation: !!omap - chebi: CHEBI:62414 - kegg.compound: C05921 + - sbo: SBO:0000247 - !!omap - id: s_0454 - name: but-1-ene-1,2,4-tricarboxylic acid @@ -3037,6 +3378,7 @@ - annotation: !!omap - chebi: CHEBI:58174 - kegg.compound: C04002 + - sbo: SBO:0000247 - !!omap - id: s_0455 - name: carbamoyl phosphate @@ -3046,6 +3388,7 @@ - annotation: !!omap - chebi: CHEBI:58228 - kegg.compound: C00169 + - sbo: SBO:0000247 - !!omap - id: s_0456 - name: carbon dioxide @@ -3055,6 +3398,7 @@ - annotation: !!omap - chebi: CHEBI:16526 - kegg.compound: C00011 + - sbo: SBO:0000247 - !!omap - id: s_0457 - name: carbon dioxide @@ -3064,6 +3408,7 @@ - annotation: !!omap - chebi: CHEBI:16526 - kegg.compound: C00011 + - sbo: SBO:0000247 - !!omap - id: s_0458 - name: carbon dioxide @@ -3073,6 +3418,7 @@ - annotation: !!omap - chebi: CHEBI:16526 - kegg.compound: C00011 + - sbo: SBO:0000247 - !!omap - id: s_0460 - name: carbon dioxide @@ -3082,6 +3428,7 @@ - annotation: !!omap - chebi: CHEBI:16526 - kegg.compound: C00011 + - sbo: SBO:0000247 - !!omap - id: s_0461 - name: carbon dioxide @@ -3091,6 +3438,7 @@ - annotation: !!omap - chebi: CHEBI:16526 - kegg.compound: C00011 + - sbo: SBO:0000247 - !!omap - id: s_0462 - name: carbon dioxide @@ -3100,6 +3448,7 @@ - annotation: !!omap - chebi: CHEBI:16526 - kegg.compound: C00011 + - sbo: SBO:0000247 - !!omap - id: s_0465 - name: carboxyacetyl-ACP @@ -3109,6 +3458,7 @@ - annotation: !!omap - chebi: CHEBI:17330 - kegg.compound: C01209 + - sbo: SBO:0000247 - !!omap - id: s_0467 - name: CDP @@ -3118,6 +3468,7 @@ - annotation: !!omap - chebi: CHEBI:58069 - kegg.compound: C00112 + - sbo: SBO:0000247 - !!omap - id: s_0468 - name: CDP @@ -3127,6 +3478,7 @@ - annotation: !!omap - chebi: CHEBI:58069 - kegg.compound: C00112 + - sbo: SBO:0000247 - !!omap - id: s_0469 - name: CDP-choline @@ -3136,6 +3488,7 @@ - annotation: !!omap - chebi: CHEBI:16436 - kegg.compound: C00307 + - sbo: SBO:0000247 - !!omap - id: s_0474 - name: CDP-ethanolamine @@ -3145,6 +3498,7 @@ - annotation: !!omap - chebi: CHEBI:57876 - kegg.compound: C00570 + - sbo: SBO:0000247 - !!omap - id: s_0475 - name: ceramide-1 (C24) @@ -3153,6 +3507,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52961 + - sbo: SBO:0000247 - !!omap - id: s_0476 - name: ceramide-1 (C24) @@ -3161,6 +3516,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52961 + - sbo: SBO:0000247 - !!omap - id: s_0477 - name: ceramide-1 (C24) @@ -3169,6 +3525,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52961 + - sbo: SBO:0000247 - !!omap - id: s_0478 - name: ceramide-1 (C26) @@ -3177,6 +3534,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52962 + - sbo: SBO:0000247 - !!omap - id: s_0479 - name: ceramide-1 (C26) @@ -3185,6 +3543,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52962 + - sbo: SBO:0000247 - !!omap - id: s_0480 - name: ceramide-1 (C26) @@ -3193,6 +3552,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52962 + - sbo: SBO:0000247 - !!omap - id: s_0481 - name: ceramide-2 (C24) @@ -3201,6 +3561,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52979 + - sbo: SBO:0000247 - !!omap - id: s_0482 - name: ceramide-2 (C24) @@ -3209,6 +3570,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52979 + - sbo: SBO:0000247 - !!omap - id: s_0483 - name: ceramide-2 (C24) @@ -3217,6 +3579,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52979 + - sbo: SBO:0000247 - !!omap - id: s_0484 - name: ceramide-2 (C26) @@ -3225,6 +3588,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52980 + - sbo: SBO:0000247 - !!omap - id: s_0485 - name: ceramide-2 (C26) @@ -3233,6 +3597,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52980 + - sbo: SBO:0000247 - !!omap - id: s_0486 - name: ceramide-2 (C26) @@ -3241,6 +3606,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52980 + - sbo: SBO:0000247 - !!omap - id: s_0487 - name: ceramide-2' (C24) @@ -3249,6 +3615,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52371 + - sbo: SBO:0000247 - !!omap - id: s_0488 - name: ceramide-2' (C24) @@ -3257,6 +3624,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52371 + - sbo: SBO:0000247 - !!omap - id: s_0489 - name: ceramide-2' (C24) @@ -3265,6 +3633,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52371 + - sbo: SBO:0000247 - !!omap - id: s_0490 - name: ceramide-2' (C26) @@ -3273,6 +3642,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52372 + - sbo: SBO:0000247 - !!omap - id: s_0491 - name: ceramide-2' (C26) @@ -3281,6 +3651,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52372 + - sbo: SBO:0000247 - !!omap - id: s_0492 - name: ceramide-2' (C26) @@ -3289,6 +3660,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52372 + - sbo: SBO:0000247 - !!omap - id: s_0493 - name: ceramide-3 (C24) @@ -3297,6 +3669,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52373 + - sbo: SBO:0000247 - !!omap - id: s_0494 - name: ceramide-3 (C24) @@ -3305,6 +3678,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52373 + - sbo: SBO:0000247 - !!omap - id: s_0495 - name: ceramide-3 (C24) @@ -3313,6 +3687,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52373 + - sbo: SBO:0000247 - !!omap - id: s_0496 - name: ceramide-3 (C26) @@ -3321,6 +3696,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52374 + - sbo: SBO:0000247 - !!omap - id: s_0497 - name: ceramide-3 (C26) @@ -3329,6 +3705,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52374 + - sbo: SBO:0000247 - !!omap - id: s_0498 - name: ceramide-3 (C26) @@ -3337,6 +3714,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52374 + - sbo: SBO:0000247 - !!omap - id: s_0499 - name: ceramide-4 (C24) @@ -3345,6 +3723,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60256 + - sbo: SBO:0000247 - !!omap - id: s_0500 - name: ceramide-4 (C24) @@ -3353,6 +3732,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60256 + - sbo: SBO:0000247 - !!omap - id: s_0501 - name: ceramide-4 (C24) @@ -3361,6 +3741,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60256 + - sbo: SBO:0000247 - !!omap - id: s_0502 - name: ceramide-4 (C26) @@ -3369,6 +3750,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60384 + - sbo: SBO:0000247 - !!omap - id: s_0503 - name: ceramide-4 (C26) @@ -3377,6 +3759,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60384 + - sbo: SBO:0000247 - !!omap - id: s_0504 - name: ceramide-4 (C26) @@ -3385,6 +3768,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60384 + - sbo: SBO:0000247 - !!omap - id: s_0507 - name: cerotic acid @@ -3393,6 +3777,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:31013 + - sbo: SBO:0000247 - !!omap - id: s_0509 - name: chitin @@ -3402,6 +3787,7 @@ - annotation: !!omap - chebi: CHEBI:17029 - kegg.compound: C00461 + - sbo: SBO:0000247 - !!omap - id: s_0510 - name: chitosan @@ -3411,6 +3797,7 @@ - annotation: !!omap - chebi: CHEBI:16261 - kegg.compound: C00734 + - sbo: SBO:0000247 - !!omap - id: s_0511 - name: choline @@ -3420,6 +3807,7 @@ - annotation: !!omap - chebi: CHEBI:15354 - kegg.compound: C00114 + - sbo: SBO:0000247 - !!omap - id: s_0512 - name: choline @@ -3429,6 +3817,7 @@ - annotation: !!omap - chebi: CHEBI:15354 - kegg.compound: C00114 + - sbo: SBO:0000247 - !!omap - id: s_0513 - name: choline @@ -3438,6 +3827,7 @@ - annotation: !!omap - chebi: CHEBI:15354 - kegg.compound: C00114 + - sbo: SBO:0000247 - !!omap - id: s_0514 - name: choline phosphate @@ -3447,6 +3837,7 @@ - annotation: !!omap - chebi: CHEBI:295975 - kegg.compound: C00588 + - sbo: SBO:0000247 - !!omap - id: s_0515 - name: chorismate @@ -3456,6 +3847,7 @@ - annotation: !!omap - chebi: CHEBI:29748 - kegg.compound: C00251 + - sbo: SBO:0000247 - !!omap - id: s_0516 - name: cis-aconitate @@ -3465,6 +3857,7 @@ - annotation: !!omap - chebi: CHEBI:16383 - kegg.compound: C00417 + - sbo: SBO:0000247 - !!omap - id: s_0517 - name: cis-aconitate @@ -3474,6 +3867,7 @@ - annotation: !!omap - chebi: CHEBI:16383 - kegg.compound: C00417 + - sbo: SBO:0000247 - !!omap - id: s_0522 - name: citrate @@ -3483,6 +3877,7 @@ - annotation: !!omap - chebi: CHEBI:16947 - kegg.compound: C00158 + - sbo: SBO:0000247 - !!omap - id: s_0523 - name: citrate @@ -3492,6 +3887,7 @@ - annotation: !!omap - chebi: CHEBI:16947 - kegg.compound: C00158 + - sbo: SBO:0000247 - !!omap - id: s_0524 - name: citrate @@ -3501,6 +3897,7 @@ - annotation: !!omap - chebi: CHEBI:16947 - kegg.compound: C00158 + - sbo: SBO:0000247 - !!omap - id: s_0525 - name: citrate @@ -3510,6 +3907,7 @@ - annotation: !!omap - chebi: CHEBI:16947 - kegg.compound: C00158 + - sbo: SBO:0000247 - !!omap - id: s_0526 - name: CMP @@ -3519,6 +3917,7 @@ - annotation: !!omap - chebi: CHEBI:60377 - kegg.compound: C00055 + - sbo: SBO:0000247 - !!omap - id: s_0528 - name: CMP @@ -3528,6 +3927,7 @@ - annotation: !!omap - chebi: CHEBI:60377 - kegg.compound: C00055 + - sbo: SBO:0000247 - !!omap - id: s_0529 - name: coenzyme A @@ -3537,6 +3937,7 @@ - annotation: !!omap - chebi: CHEBI:57287 - kegg.compound: C00010 + - sbo: SBO:0000247 - !!omap - id: s_0530 - name: coenzyme A @@ -3546,6 +3947,7 @@ - annotation: !!omap - chebi: CHEBI:57287 - kegg.compound: C00010 + - sbo: SBO:0000247 - !!omap - id: s_0531 - name: coenzyme A @@ -3555,6 +3957,7 @@ - annotation: !!omap - chebi: CHEBI:57287 - kegg.compound: C00010 + - sbo: SBO:0000247 - !!omap - id: s_0532 - name: coenzyme A @@ -3564,6 +3967,7 @@ - annotation: !!omap - chebi: CHEBI:57287 - kegg.compound: C00010 + - sbo: SBO:0000247 - !!omap - id: s_0533 - name: coenzyme A @@ -3573,6 +3977,7 @@ - annotation: !!omap - chebi: CHEBI:57287 - kegg.compound: C00010 + - sbo: SBO:0000247 - !!omap - id: s_0534 - name: coenzyme A @@ -3582,6 +3987,7 @@ - annotation: !!omap - chebi: CHEBI:57287 - kegg.compound: C00010 + - sbo: SBO:0000247 - !!omap - id: s_0538 - name: coproporphyrinogen III @@ -3591,6 +3997,7 @@ - annotation: !!omap - chebi: CHEBI:57309 - kegg.compound: C03263 + - sbo: SBO:0000247 - !!omap - id: s_0539 - name: CTP @@ -3600,6 +4007,7 @@ - annotation: !!omap - chebi: CHEBI:37563 - kegg.compound: C00063 + - sbo: SBO:0000247 - !!omap - id: s_0541 - name: CTP @@ -3609,6 +4017,7 @@ - annotation: !!omap - chebi: CHEBI:37563 - kegg.compound: C00063 + - sbo: SBO:0000247 - !!omap - id: s_0542 - name: Cys-tRNA(Cys) @@ -3618,6 +4027,7 @@ - annotation: !!omap - chebi: CHEBI:29152 - kegg.compound: C03125 + - sbo: SBO:0000247 - !!omap - id: s_0543 - name: cytidine @@ -3627,6 +4037,7 @@ - annotation: !!omap - chebi: CHEBI:17562 - kegg.compound: C00475 + - sbo: SBO:0000247 - !!omap - id: s_0544 - name: cytidine @@ -3636,6 +4047,7 @@ - annotation: !!omap - chebi: CHEBI:17562 - kegg.compound: C00475 + - sbo: SBO:0000247 - !!omap - id: s_0545 - name: cytosine @@ -3645,6 +4057,7 @@ - annotation: !!omap - chebi: CHEBI:16040 - kegg.compound: C00380 + - sbo: SBO:0000247 - !!omap - id: s_0546 - name: cytosine @@ -3654,6 +4067,7 @@ - annotation: !!omap - chebi: CHEBI:16040 - kegg.compound: C00380 + - sbo: SBO:0000247 - !!omap - id: s_0547 - name: D-arabinono-1,4-lactone @@ -3663,6 +4077,7 @@ - annotation: !!omap - chebi: CHEBI:16292 - kegg.compound: C00652 + - sbo: SBO:0000247 - !!omap - id: s_0548 - name: D-arabinose @@ -3672,6 +4087,7 @@ - annotation: !!omap - chebi: CHEBI:17108 - kegg.compound: C00216 + - sbo: SBO:0000247 - !!omap - id: s_0549 - name: D-arabinose @@ -3681,6 +4097,7 @@ - annotation: !!omap - chebi: CHEBI:17108 - kegg.compound: C00216 + - sbo: SBO:0000247 - !!omap - id: s_0550 - name: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate @@ -3690,6 +4107,7 @@ - annotation: !!omap - chebi: CHEBI:58278 - kegg.compound: C04666 + - sbo: SBO:0000247 - !!omap - id: s_0551 - name: D-erythrose 4-phosphate @@ -3699,6 +4117,7 @@ - annotation: !!omap - chebi: CHEBI:16897 - kegg.compound: C00279 + - sbo: SBO:0000247 - !!omap - id: s_0552 - name: D-erythrose 4-phosphate @@ -3708,6 +4127,7 @@ - annotation: !!omap - chebi: CHEBI:16897 - kegg.compound: C00279 + - sbo: SBO:0000247 - !!omap - id: s_0553 - name: D-fructose @@ -3717,6 +4137,7 @@ - annotation: !!omap - chebi: CHEBI:15824 - kegg.compound: C00095 + - sbo: SBO:0000247 - !!omap - id: s_0554 - name: D-fructose @@ -3726,6 +4147,7 @@ - annotation: !!omap - chebi: CHEBI:15824 - kegg.compound: C00095 + - sbo: SBO:0000247 - !!omap - id: s_0555 - name: D-fructose 1,6-bisphosphate @@ -3735,6 +4157,7 @@ - annotation: !!omap - chebi: CHEBI:16905 - kegg.compound: C00354 + - sbo: SBO:0000247 - !!omap - id: s_0556 - name: D-fructose 1-phosphate @@ -3744,6 +4167,7 @@ - annotation: !!omap - chebi: CHEBI:18105 - kegg.compound: C01094 + - sbo: SBO:0000247 - !!omap - id: s_0557 - name: D-fructose 6-phosphate @@ -3753,6 +4177,7 @@ - annotation: !!omap - chebi: CHEBI:57579 - kegg.compound: C00085 + - sbo: SBO:0000247 - !!omap - id: s_0558 - name: D-galactose @@ -3762,6 +4187,7 @@ - annotation: !!omap - chebi: CHEBI:12936 - kegg.compound: C00124 + - sbo: SBO:0000247 - !!omap - id: s_0559 - name: D-galactose @@ -3771,6 +4197,7 @@ - annotation: !!omap - chebi: CHEBI:12936 - kegg.compound: C00124 + - sbo: SBO:0000247 - !!omap - id: s_0560 - name: D-galacturonate @@ -3780,6 +4207,7 @@ - annotation: !!omap - chebi: CHEBI:12952 - kegg.compound: C00333 + - sbo: SBO:0000247 - !!omap - id: s_0561 - name: D-glucitol @@ -3789,6 +4217,7 @@ - annotation: !!omap - chebi: CHEBI:17924 - kegg.compound: C00794 + - sbo: SBO:0000247 - !!omap - id: s_0562 - name: D-glucitol @@ -3798,6 +4227,7 @@ - annotation: !!omap - chebi: CHEBI:17924 - kegg.compound: C00794 + - sbo: SBO:0000247 - !!omap - id: s_0563 - name: D-glucose @@ -3807,6 +4237,7 @@ - annotation: !!omap - chebi: CHEBI:4167 - kegg.compound: C00031 + - sbo: SBO:0000247 - !!omap - id: s_0565 - name: D-glucose @@ -3816,6 +4247,7 @@ - annotation: !!omap - chebi: CHEBI:4167 - kegg.compound: C00031 + - sbo: SBO:0000247 - !!omap - id: s_0566 - name: D-glucose @@ -3825,6 +4257,7 @@ - annotation: !!omap - chebi: CHEBI:4167 - kegg.compound: C00031 + - sbo: SBO:0000247 - !!omap - id: s_0567 - name: D-glucose 1-phosphate @@ -3834,6 +4267,7 @@ - annotation: !!omap - chebi: CHEBI:57629 - kegg.compound: C00103 + - sbo: SBO:0000247 - !!omap - id: s_0568 - name: D-glucose 6-phosphate @@ -3843,6 +4277,7 @@ - annotation: !!omap - chebi: CHEBI:14314 - kegg.compound: C00092 + - sbo: SBO:0000247 - !!omap - id: s_0570 - name: D-glyceraldehyde @@ -3852,6 +4287,7 @@ - annotation: !!omap - chebi: CHEBI:17378 - kegg.compound: C00577 + - sbo: SBO:0000247 - !!omap - id: s_0571 - name: D-mannose @@ -3861,6 +4297,7 @@ - annotation: !!omap - chebi: CHEBI:16024 - kegg.compound: C00159 + - sbo: SBO:0000247 - !!omap - id: s_0572 - name: D-mannose @@ -3870,6 +4307,7 @@ - annotation: !!omap - chebi: CHEBI:16024 - kegg.compound: C00159 + - sbo: SBO:0000247 - !!omap - id: s_0573 - name: D-mannose 1-phosphate @@ -3879,6 +4317,7 @@ - annotation: !!omap - chebi: CHEBI:35374 - kegg.compound: C00636 + - sbo: SBO:0000247 - !!omap - id: s_0574 - name: D-mannose 6-phosphate @@ -3888,6 +4327,7 @@ - annotation: !!omap - chebi: CHEBI:17369 - kegg.compound: C00275 + - sbo: SBO:0000247 - !!omap - id: s_0575 - name: D-ribose @@ -3897,6 +4337,7 @@ - annotation: !!omap - chebi: CHEBI:16988 - kegg.compound: C00121 + - sbo: SBO:0000247 - !!omap - id: s_0576 - name: D-ribose @@ -3906,6 +4347,7 @@ - annotation: !!omap - chebi: CHEBI:16988 - kegg.compound: C00121 + - sbo: SBO:0000247 - !!omap - id: s_0577 - name: D-ribulose 5-phosphate @@ -3915,6 +4357,7 @@ - annotation: !!omap - chebi: CHEBI:58121 - kegg.compound: C00199 + - sbo: SBO:0000247 - !!omap - id: s_0578 - name: D-xylose @@ -3924,6 +4367,7 @@ - annotation: !!omap - chebi: CHEBI:15936 - kegg.compound: C00181 + - sbo: SBO:0000247 - !!omap - id: s_0579 - name: D-xylose @@ -3933,6 +4377,7 @@ - annotation: !!omap - chebi: CHEBI:15936 - kegg.compound: C00181 + - sbo: SBO:0000247 - !!omap - id: s_0580 - name: D-xylulose @@ -3942,6 +4387,7 @@ - annotation: !!omap - chebi: CHEBI:17140 - kegg.compound: C00310 + - sbo: SBO:0000247 - !!omap - id: s_0581 - name: D-xylulose 5-phosphate @@ -3951,6 +4397,7 @@ - annotation: !!omap - chebi: CHEBI:57737 - kegg.compound: C00231 + - sbo: SBO:0000247 - !!omap - id: s_0582 - name: dADP @@ -3960,6 +4407,7 @@ - annotation: !!omap - chebi: CHEBI:57667 - kegg.compound: C00206 + - sbo: SBO:0000247 - !!omap - id: s_0583 - name: dADP @@ -3969,6 +4417,7 @@ - annotation: !!omap - chebi: CHEBI:57667 - kegg.compound: C00206 + - sbo: SBO:0000247 - !!omap - id: s_0584 - name: dAMP @@ -3978,6 +4427,7 @@ - annotation: !!omap - chebi: CHEBI:58245 - kegg.compound: C00360 + - sbo: SBO:0000247 - !!omap - id: s_0585 - name: dAMP @@ -3987,6 +4437,7 @@ - annotation: !!omap - chebi: CHEBI:58245 - kegg.compound: C00360 + - sbo: SBO:0000247 - !!omap - id: s_0586 - name: dATP @@ -3996,6 +4447,7 @@ - annotation: !!omap - chebi: CHEBI:61404 - kegg.compound: C00131 + - sbo: SBO:0000247 - !!omap - id: s_0587 - name: dCDP @@ -4005,6 +4457,7 @@ - annotation: !!omap - chebi: CHEBI:58593 - kegg.compound: C00705 + - sbo: SBO:0000247 - !!omap - id: s_0588 - name: dCDP @@ -4014,6 +4467,7 @@ - annotation: !!omap - chebi: CHEBI:58593 - kegg.compound: C00705 + - sbo: SBO:0000247 - !!omap - id: s_0589 - name: dCMP @@ -4023,6 +4477,7 @@ - annotation: !!omap - chebi: CHEBI:57566 - kegg.compound: C00239 + - sbo: SBO:0000247 - !!omap - id: s_0590 - name: dCTP @@ -4032,6 +4487,7 @@ - annotation: !!omap - chebi: CHEBI:57724 - kegg.compound: C00458 + - sbo: SBO:0000247 - !!omap - id: s_0591 - name: deamido-NAD(+) @@ -4041,6 +4497,7 @@ - annotation: !!omap - chebi: CHEBI:18304 - kegg.compound: C00857 + - sbo: SBO:0000247 - !!omap - id: s_0593 - name: deamido-NAD(+) @@ -4050,6 +4507,7 @@ - annotation: !!omap - chebi: CHEBI:18304 - kegg.compound: C00857 + - sbo: SBO:0000247 - !!omap - id: s_0595 - name: decanoate @@ -4059,6 +4517,7 @@ - annotation: !!omap - chebi: CHEBI:27689 - kegg.compound: C01571 + - sbo: SBO:0000247 - !!omap - id: s_0597 - name: decanoate @@ -4068,6 +4527,7 @@ - annotation: !!omap - chebi: CHEBI:27689 - kegg.compound: C01571 + - sbo: SBO:0000247 - !!omap - id: s_0600 - name: decanoate @@ -4077,6 +4537,7 @@ - annotation: !!omap - chebi: CHEBI:27689 - kegg.compound: C01571 + - sbo: SBO:0000247 - !!omap - id: s_0605 - name: decanoyl-CoA @@ -4086,6 +4547,7 @@ - annotation: !!omap - chebi: CHEBI:61430 - kegg.compound: C05274 + - sbo: SBO:0000247 - !!omap - id: s_0606 - name: decaprenyl diphosphate @@ -4095,6 +4557,7 @@ - annotation: !!omap - chebi: CHEBI:53043 - kegg.compound: C17432 + - sbo: SBO:0000247 - !!omap - id: s_0607 - name: dehydro-D-arabinono-1,4-lactone @@ -4104,6 +4567,7 @@ - annotation: !!omap - chebi: CHEBI:58277 - kegg.compound: C06316 + - sbo: SBO:0000247 - !!omap - id: s_0608 - name: Delta(6)-trans,Delta(8)-cis-leukotriene B4 @@ -4112,6 +4576,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53027 + - sbo: SBO:0000247 - !!omap - id: s_0609 - name: Delta(6)-trans,Delta(8)-cis-leukotriene B4 @@ -4120,6 +4585,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53027 + - sbo: SBO:0000247 - !!omap - id: s_0610 - name: deoxycytidine @@ -4129,6 +4595,7 @@ - annotation: !!omap - chebi: CHEBI:15698 - kegg.compound: C00881 + - sbo: SBO:0000247 - !!omap - id: s_0611 - name: deoxycytidine @@ -4138,6 +4605,7 @@ - annotation: !!omap - chebi: CHEBI:15698 - kegg.compound: C00881 + - sbo: SBO:0000247 - !!omap - id: s_0612 - name: dethiobiotin @@ -4147,6 +4615,7 @@ - annotation: !!omap - chebi: CHEBI:57861 - kegg.compound: C01909 + - sbo: SBO:0000247 - !!omap - id: s_0613 - name: dGDP @@ -4156,6 +4625,7 @@ - annotation: !!omap - chebi: CHEBI:58595 - kegg.compound: C00361 + - sbo: SBO:0000247 - !!omap - id: s_0614 - name: dGDP @@ -4165,6 +4635,7 @@ - annotation: !!omap - chebi: CHEBI:58595 - kegg.compound: C00361 + - sbo: SBO:0000247 - !!omap - id: s_0615 - name: dGMP @@ -4174,6 +4645,7 @@ - annotation: !!omap - chebi: CHEBI:57673 - kegg.compound: C00362 + - sbo: SBO:0000247 - !!omap - id: s_0616 - name: dGMP @@ -4183,6 +4655,7 @@ - annotation: !!omap - chebi: CHEBI:57673 - kegg.compound: C00362 + - sbo: SBO:0000247 - !!omap - id: s_0617 - name: dGTP @@ -4192,6 +4665,7 @@ - annotation: !!omap - chebi: CHEBI:57794 - kegg.compound: C00286 + - sbo: SBO:0000247 - !!omap - id: s_0618 - name: dIDP @@ -4201,6 +4675,7 @@ - annotation: !!omap - chebi: CHEBI:28823 - kegg.compound: C01344 + - sbo: SBO:0000247 - !!omap - id: s_0620 - name: diglyceride backbone @@ -4209,6 +4684,7 @@ - annotation: !!omap - chebi: CHEBI:18035 - kegg.compound: C00165 + - sbo: SBO:0000649 - !!omap - id: s_0625 - name: dihydrofolic acid @@ -4218,6 +4694,7 @@ - annotation: !!omap - chebi: CHEBI:57451 - kegg.compound: C00415 + - sbo: SBO:0000247 - !!omap - id: s_0626 - name: dihydrofolic acid @@ -4227,6 +4704,7 @@ - annotation: !!omap - chebi: CHEBI:57451 - kegg.compound: C00415 + - sbo: SBO:0000247 - !!omap - id: s_0627 - name: dihydrolipoamide @@ -4236,6 +4714,7 @@ - annotation: !!omap - chebi: CHEBI:17694 - kegg.compound: C00579 + - sbo: SBO:0000247 - !!omap - id: s_0628 - name: dihydrolipoylprotein @@ -4245,6 +4724,7 @@ - annotation: !!omap - chebi: CHEBI:16194 - kegg.compound: C02972 + - sbo: SBO:0000247 - !!omap - id: s_0629 - name: dihydroxyacetone phosphate @@ -4254,6 +4734,7 @@ - annotation: !!omap - chebi: CHEBI:57642 - kegg.compound: C00111 + - sbo: SBO:0000247 - !!omap - id: s_0631 - name: dihydroxyacetone phosphate @@ -4263,6 +4744,7 @@ - annotation: !!omap - chebi: CHEBI:57642 - kegg.compound: C00111 + - sbo: SBO:0000247 - !!omap - id: s_0632 - name: dihydroxyacetone phosphate @@ -4272,6 +4754,7 @@ - annotation: !!omap - chebi: CHEBI:57642 - kegg.compound: C00111 + - sbo: SBO:0000247 - !!omap - id: s_0633 - name: diphosphate @@ -4281,6 +4764,7 @@ - annotation: !!omap - chebi: CHEBI:33019 - kegg.compound: C00013 + - sbo: SBO:0000247 - !!omap - id: s_0635 - name: diphosphate @@ -4290,6 +4774,7 @@ - annotation: !!omap - chebi: CHEBI:33019 - kegg.compound: C00013 + - sbo: SBO:0000247 - !!omap - id: s_0636 - name: diphosphate @@ -4299,6 +4784,7 @@ - annotation: !!omap - chebi: CHEBI:33019 - kegg.compound: C00013 + - sbo: SBO:0000247 - !!omap - id: s_0637 - name: diphosphate @@ -4308,6 +4794,7 @@ - annotation: !!omap - chebi: CHEBI:33019 - kegg.compound: C00013 + - sbo: SBO:0000247 - !!omap - id: s_0638 - name: diphosphate @@ -4317,6 +4804,7 @@ - annotation: !!omap - chebi: CHEBI:33019 - kegg.compound: C00013 + - sbo: SBO:0000247 - !!omap - id: s_0639 - name: dITP @@ -4326,6 +4814,7 @@ - annotation: !!omap - chebi: CHEBI:61382 - kegg.compound: C01345 + - sbo: SBO:0000247 - !!omap - id: s_0640 - name: docosaprenyl diphosphate @@ -4334,6 +4823,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53031 + - sbo: SBO:0000247 - !!omap - id: s_0641 - name: dodecaprenyl diphosphate @@ -4342,6 +4832,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53041 + - sbo: SBO:0000247 - !!omap - id: s_0642 - name: dolichol @@ -4351,6 +4842,7 @@ - annotation: !!omap - chebi: CHEBI:16091 - kegg.compound: C00381 + - sbo: SBO:0000247 - !!omap - id: s_0644 - name: dolichyl D-mannosyl phosphate @@ -4360,6 +4852,7 @@ - annotation: !!omap - chebi: CHEBI:15809 - kegg.compound: C03862 + - sbo: SBO:0000247 - !!omap - id: s_0645 - name: dolichyl phosphate @@ -4369,6 +4862,7 @@ - annotation: !!omap - chebi: CHEBI:16214 - kegg.compound: C00110 + - sbo: SBO:0000247 - !!omap - id: s_0646 - name: dolichyl phosphate @@ -4378,6 +4872,7 @@ - annotation: !!omap - chebi: CHEBI:16214 - kegg.compound: C00110 + - sbo: SBO:0000247 - !!omap - id: s_0647 - name: dTDP @@ -4387,6 +4882,7 @@ - annotation: !!omap - chebi: CHEBI:58369 - kegg.compound: C00363 + - sbo: SBO:0000247 - !!omap - id: s_0649 - name: dTMP @@ -4396,6 +4892,7 @@ - annotation: !!omap - chebi: CHEBI:17013 - kegg.compound: C00364 + - sbo: SBO:0000247 - !!omap - id: s_0650 - name: dTTP @@ -4405,6 +4902,7 @@ - annotation: !!omap - chebi: CHEBI:58370 - kegg.compound: C00459 + - sbo: SBO:0000247 - !!omap - id: s_0651 - name: dTTP @@ -4414,6 +4912,7 @@ - annotation: !!omap - chebi: CHEBI:58370 - kegg.compound: C00459 + - sbo: SBO:0000247 - !!omap - id: s_0652 - name: dUDP @@ -4423,6 +4922,7 @@ - annotation: !!omap - chebi: CHEBI:60471 - kegg.compound: C01346 + - sbo: SBO:0000247 - !!omap - id: s_0653 - name: dUDP @@ -4432,6 +4932,7 @@ - annotation: !!omap - chebi: CHEBI:60471 - kegg.compound: C01346 + - sbo: SBO:0000247 - !!omap - id: s_0654 - name: dUMP @@ -4441,6 +4942,7 @@ - annotation: !!omap - chebi: CHEBI:246422 - kegg.compound: C00365 + - sbo: SBO:0000247 - !!omap - id: s_0655 - name: dUMP @@ -4450,6 +4952,7 @@ - annotation: !!omap - chebi: CHEBI:246422 - kegg.compound: C00365 + - sbo: SBO:0000247 - !!omap - id: s_0656 - name: dUTP @@ -4459,6 +4962,7 @@ - annotation: !!omap - chebi: CHEBI:58212 - kegg.compound: C00460 + - sbo: SBO:0000247 - !!omap - id: s_0657 - name: episterol @@ -4468,6 +4972,7 @@ - annotation: !!omap - chebi: CHEBI:23929 - kegg.compound: C15777 + - sbo: SBO:0000247 - !!omap - id: s_0659 - name: episterol @@ -4477,6 +4982,7 @@ - annotation: !!omap - chebi: CHEBI:23929 - kegg.compound: C15777 + - sbo: SBO:0000247 - !!omap - id: s_0662 - name: ergosta-5,7,22,24(28)-tetraen-3beta-ol @@ -4486,6 +4992,7 @@ - annotation: !!omap - chebi: CHEBI:18249 - kegg.compound: C05440 + - sbo: SBO:0000247 - !!omap - id: s_0663 - name: ergosta-5,7,22,24(28)-tetraen-3beta-ol @@ -4495,6 +5002,7 @@ - annotation: !!omap - chebi: CHEBI:18249 - kegg.compound: C05440 + - sbo: SBO:0000247 - !!omap - id: s_0664 - name: ergosta-5,7,24(28)-trien-3beta-ol @@ -4504,6 +5012,7 @@ - annotation: !!omap - chebi: CHEBI:52972 - kegg.compound: C15780 + - sbo: SBO:0000247 - !!omap - id: s_0665 - name: ergosterol @@ -4513,6 +5022,7 @@ - annotation: !!omap - chebi: CHEBI:16933 - kegg.compound: C01694 + - sbo: SBO:0000247 - !!omap - id: s_0666 - name: ergosterol @@ -4522,6 +5032,7 @@ - annotation: !!omap - chebi: CHEBI:16933 - kegg.compound: C01694 + - sbo: SBO:0000247 - !!omap - id: s_0667 - name: ergosterol @@ -4531,6 +5042,7 @@ - annotation: !!omap - chebi: CHEBI:16933 - kegg.compound: C01694 + - sbo: SBO:0000247 - !!omap - id: s_0668 - name: ergosterol @@ -4540,6 +5052,7 @@ - annotation: !!omap - chebi: CHEBI:16933 - kegg.compound: C01694 + - sbo: SBO:0000247 - !!omap - id: s_0669 - name: ergosterol @@ -4549,6 +5062,7 @@ - annotation: !!omap - chebi: CHEBI:16933 - kegg.compound: C01694 + - sbo: SBO:0000247 - !!omap - id: s_0670 - name: ergosterol 3-beta-D-glucoside @@ -4557,6 +5071,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52973 + - sbo: SBO:0000247 - !!omap - id: s_0672 - name: ergosterol ester backbone @@ -4565,6 +5080,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52320 + - sbo: SBO:0000649 - !!omap - id: s_0677 - name: erythro-4-hydroxy-L-glutamic acid @@ -4574,6 +5090,7 @@ - annotation: !!omap - chebi: CHEBI:21285 - kegg.compound: C05947 + - sbo: SBO:0000247 - !!omap - id: s_0678 - name: erythro-4-hydroxy-L-glutamic acid @@ -4583,6 +5100,7 @@ - annotation: !!omap - chebi: CHEBI:21285 - kegg.compound: C05947 + - sbo: SBO:0000247 - !!omap - id: s_0679 - name: erythro-4-hydroxy-L-glutamic acid @@ -4592,6 +5110,7 @@ - annotation: !!omap - chebi: CHEBI:21285 - kegg.compound: C05947 + - sbo: SBO:0000247 - !!omap - id: s_0680 - name: ethanol @@ -4601,6 +5120,7 @@ - annotation: !!omap - chebi: CHEBI:16236 - kegg.compound: C00469 + - sbo: SBO:0000247 - !!omap - id: s_0681 - name: ethanol @@ -4610,6 +5130,7 @@ - annotation: !!omap - chebi: CHEBI:16236 - kegg.compound: C00469 + - sbo: SBO:0000247 - !!omap - id: s_0682 - name: ethanol @@ -4619,6 +5140,7 @@ - annotation: !!omap - chebi: CHEBI:16236 - kegg.compound: C00469 + - sbo: SBO:0000247 - !!omap - id: s_0683 - name: ethanolamine @@ -4628,6 +5150,7 @@ - annotation: !!omap - chebi: CHEBI:57603 - kegg.compound: C00189 + - sbo: SBO:0000247 - !!omap - id: s_0684 - name: ethanolamine @@ -4637,6 +5160,7 @@ - annotation: !!omap - chebi: CHEBI:57603 - kegg.compound: C00189 + - sbo: SBO:0000247 - !!omap - id: s_0685 - name: ethyl acetate @@ -4646,6 +5170,7 @@ - annotation: !!omap - chebi: CHEBI:27750 - kegg.compound: C00849 + - sbo: SBO:0000247 - !!omap - id: s_0686 - name: ethyl acetate @@ -4655,6 +5180,7 @@ - annotation: !!omap - chebi: CHEBI:27750 - kegg.compound: C00849 + - sbo: SBO:0000247 - !!omap - id: s_0687 - name: FAD @@ -4664,6 +5190,7 @@ - annotation: !!omap - chebi: CHEBI:57692 - kegg.compound: C00016 + - sbo: SBO:0000247 - !!omap - id: s_0688 - name: FAD @@ -4673,6 +5200,7 @@ - annotation: !!omap - chebi: CHEBI:57692 - kegg.compound: C00016 + - sbo: SBO:0000247 - !!omap - id: s_0689 - name: FADH2 @@ -4682,6 +5210,7 @@ - annotation: !!omap - chebi: CHEBI:58307 - kegg.compound: C01352 + - sbo: SBO:0000247 - !!omap - id: s_0690 - name: FADH2 @@ -4691,6 +5220,7 @@ - annotation: !!omap - chebi: CHEBI:58307 - kegg.compound: C01352 + - sbo: SBO:0000247 - !!omap - id: s_0692 - name: farnesyl diphosphate @@ -4700,6 +5230,7 @@ - annotation: !!omap - chebi: CHEBI:175763 - kegg.compound: C00448 + - sbo: SBO:0000247 - !!omap - id: s_0694 - name: fatty acid backbone @@ -4708,6 +5239,7 @@ - annotation: !!omap - chebi: CHEBI:35366 - kegg.compound: C00162 + - sbo: SBO:0000649 - !!omap - id: s_0699 - name: fecosterol @@ -4717,6 +5249,7 @@ - annotation: !!omap - chebi: CHEBI:17038 - kegg.compound: C04525 + - sbo: SBO:0000247 - !!omap - id: s_0700 - name: fecosterol @@ -4726,6 +5259,7 @@ - annotation: !!omap - chebi: CHEBI:17038 - kegg.compound: C04525 + - sbo: SBO:0000247 - !!omap - id: s_0702 - name: fecosterol @@ -4735,6 +5269,7 @@ - annotation: !!omap - chebi: CHEBI:17038 - kegg.compound: C04525 + - sbo: SBO:0000247 - !!omap - id: s_0703 - name: fecosterol @@ -4744,6 +5279,7 @@ - annotation: !!omap - chebi: CHEBI:17038 - kegg.compound: C04525 + - sbo: SBO:0000247 - !!omap - id: s_0709 - name: ferricytochrome c @@ -4752,6 +5288,7 @@ - annotation: !!omap - chebi: CHEBI:15991 - kegg.compound: C00125 + - sbo: SBO:0000247 - !!omap - id: s_0710 - name: ferrocytochrome c @@ -4760,6 +5297,7 @@ - annotation: !!omap - chebi: CHEBI:16928 - kegg.compound: C00126 + - sbo: SBO:0000247 - !!omap - id: s_0712 - name: ferroheme b @@ -4769,6 +5307,7 @@ - annotation: !!omap - chebi: CHEBI:60344 - kegg.compound: C00032 + - sbo: SBO:0000247 - !!omap - id: s_0713 - name: fMet-tRNA(fMet) @@ -4778,6 +5317,7 @@ - annotation: !!omap - chebi: CHEBI:17119 - kegg.compound: C03294 + - sbo: SBO:0000247 - !!omap - id: s_0714 - name: FMN @@ -4787,6 +5327,7 @@ - annotation: !!omap - chebi: CHEBI:58210 - kegg.compound: C00061 + - sbo: SBO:0000247 - !!omap - id: s_0715 - name: FMN @@ -4796,6 +5337,7 @@ - annotation: !!omap - chebi: CHEBI:58210 - kegg.compound: C00061 + - sbo: SBO:0000247 - !!omap - id: s_0716 - name: FMN @@ -4805,6 +5347,7 @@ - annotation: !!omap - chebi: CHEBI:58210 - kegg.compound: C00061 + - sbo: SBO:0000247 - !!omap - id: s_0717 - name: FMNH2 @@ -4814,6 +5357,7 @@ - annotation: !!omap - chebi: CHEBI:57618 - kegg.compound: C01847 + - sbo: SBO:0000247 - !!omap - id: s_0719 - name: folate @@ -4823,6 +5367,7 @@ - annotation: !!omap - chebi: CHEBI:62501 - kegg.compound: C00504 + - sbo: SBO:0000247 - !!omap - id: s_0720 - name: folate @@ -4832,6 +5377,7 @@ - annotation: !!omap - chebi: CHEBI:62501 - kegg.compound: C00504 + - sbo: SBO:0000247 - !!omap - id: s_0721 - name: formaldehyde @@ -4841,6 +5387,7 @@ - annotation: !!omap - chebi: CHEBI:16842 - kegg.compound: C00067 + - sbo: SBO:0000247 - !!omap - id: s_0722 - name: formate @@ -4850,6 +5397,7 @@ - annotation: !!omap - chebi: CHEBI:15740 - kegg.compound: C00058 + - sbo: SBO:0000247 - !!omap - id: s_0723 - name: formate @@ -4859,6 +5407,7 @@ - annotation: !!omap - chebi: CHEBI:15740 - kegg.compound: C00058 + - sbo: SBO:0000247 - !!omap - id: s_0724 - name: formate @@ -4868,6 +5417,7 @@ - annotation: !!omap - chebi: CHEBI:15740 - kegg.compound: C00058 + - sbo: SBO:0000247 - !!omap - id: s_0725 - name: fumarate @@ -4877,6 +5427,7 @@ - annotation: !!omap - chebi: CHEBI:29806 - kegg.compound: C00122 + - sbo: SBO:0000247 - !!omap - id: s_0726 - name: fumarate @@ -4886,6 +5437,7 @@ - annotation: !!omap - chebi: CHEBI:29806 - kegg.compound: C00122 + - sbo: SBO:0000247 - !!omap - id: s_0727 - name: fumarate @@ -4895,6 +5447,7 @@ - annotation: !!omap - chebi: CHEBI:29806 - kegg.compound: C00122 + - sbo: SBO:0000247 - !!omap - id: s_0734 - name: gamma-aminobutyrate @@ -4904,6 +5457,7 @@ - annotation: !!omap - chebi: CHEBI:16865 - kegg.compound: C00334 + - sbo: SBO:0000247 - !!omap - id: s_0736 - name: gamma-aminobutyrate @@ -4913,6 +5467,7 @@ - annotation: !!omap - chebi: CHEBI:16865 - kegg.compound: C00334 + - sbo: SBO:0000247 - !!omap - id: s_0738 - name: gamma-aminobutyrate @@ -4922,6 +5477,7 @@ - annotation: !!omap - chebi: CHEBI:16865 - kegg.compound: C00334 + - sbo: SBO:0000247 - !!omap - id: s_0739 - name: GDP @@ -4931,6 +5487,7 @@ - annotation: !!omap - chebi: CHEBI:58189 - kegg.compound: C00035 + - sbo: SBO:0000247 - !!omap - id: s_0740 - name: GDP @@ -4940,6 +5497,7 @@ - annotation: !!omap - chebi: CHEBI:58189 - kegg.compound: C00035 + - sbo: SBO:0000247 - !!omap - id: s_0741 - name: GDP @@ -4949,6 +5507,7 @@ - annotation: !!omap - chebi: CHEBI:58189 - kegg.compound: C00035 + - sbo: SBO:0000247 - !!omap - id: s_0742 - name: GDP @@ -4958,6 +5517,7 @@ - annotation: !!omap - chebi: CHEBI:58189 - kegg.compound: C00035 + - sbo: SBO:0000247 - !!omap - id: s_0743 - name: GDP-alpha-D-mannose @@ -4967,6 +5527,7 @@ - annotation: !!omap - chebi: CHEBI:57527 - kegg.compound: C00096 + - sbo: SBO:0000247 - !!omap - id: s_0744 - name: GDP-alpha-D-mannose @@ -4976,6 +5537,7 @@ - annotation: !!omap - chebi: CHEBI:57527 - kegg.compound: C00096 + - sbo: SBO:0000247 - !!omap - id: s_0745 - name: geranyl diphosphate @@ -4985,6 +5547,7 @@ - annotation: !!omap - chebi: CHEBI:58057 - kegg.compound: C00341 + - sbo: SBO:0000247 - !!omap - id: s_0746 - name: geranylgeranyl diphosphate @@ -4994,6 +5557,7 @@ - annotation: !!omap - chebi: CHEBI:58756 - kegg.compound: C00353 + - sbo: SBO:0000247 - !!omap - id: s_0747 - name: Gln-tRNA(Gln) @@ -5003,6 +5567,7 @@ - annotation: !!omap - chebi: CHEBI:29166 - kegg.compound: C02282 + - sbo: SBO:0000247 - !!omap - id: s_0748 - name: Glu-tRNA(Glu) @@ -5012,6 +5577,7 @@ - annotation: !!omap - chebi: CHEBI:29157 - kegg.compound: C02987 + - sbo: SBO:0000247 - !!omap - id: s_0749 - name: Glu-tRNA(Glu) @@ -5021,6 +5587,7 @@ - annotation: !!omap - chebi: CHEBI:29157 - kegg.compound: C02987 + - sbo: SBO:0000247 - !!omap - id: s_0750 - name: glutathione @@ -5030,6 +5597,7 @@ - annotation: !!omap - chebi: CHEBI:57925 - kegg.compound: C00051 + - sbo: SBO:0000247 - !!omap - id: s_0751 - name: glutathione @@ -5039,6 +5607,7 @@ - annotation: !!omap - chebi: CHEBI:57925 - kegg.compound: C00051 + - sbo: SBO:0000247 - !!omap - id: s_0752 - name: glutathione @@ -5048,6 +5617,7 @@ - annotation: !!omap - chebi: CHEBI:57925 - kegg.compound: C00051 + - sbo: SBO:0000247 - !!omap - id: s_0753 - name: glutathione @@ -5057,6 +5627,7 @@ - annotation: !!omap - chebi: CHEBI:57925 - kegg.compound: C00051 + - sbo: SBO:0000247 - !!omap - id: s_0754 - name: glutathione disulfide @@ -5066,6 +5637,7 @@ - annotation: !!omap - chebi: CHEBI:58297 - kegg.compound: C00127 + - sbo: SBO:0000247 - !!omap - id: s_0755 - name: glutathione disulfide @@ -5075,6 +5647,7 @@ - annotation: !!omap - chebi: CHEBI:58297 - kegg.compound: C00127 + - sbo: SBO:0000247 - !!omap - id: s_0756 - name: glutathione disulfide @@ -5084,6 +5657,7 @@ - annotation: !!omap - chebi: CHEBI:58297 - kegg.compound: C00127 + - sbo: SBO:0000247 - !!omap - id: s_0757 - name: Gly-tRNA(Gly) @@ -5093,6 +5667,7 @@ - annotation: !!omap - chebi: CHEBI:29156 - kegg.compound: C02412 + - sbo: SBO:0000247 - !!omap - id: s_0764 - name: glyceraldehyde 3-phosphate @@ -5102,6 +5677,7 @@ - annotation: !!omap - chebi: CHEBI:58027 - kegg.compound: C00661 + - sbo: SBO:0000247 - !!omap - id: s_0765 - name: glycerol @@ -5111,6 +5687,7 @@ - annotation: !!omap - chebi: CHEBI:17754 - kegg.compound: C00116 + - sbo: SBO:0000247 - !!omap - id: s_0766 - name: glycerol @@ -5120,6 +5697,7 @@ - annotation: !!omap - chebi: CHEBI:17754 - kegg.compound: C00116 + - sbo: SBO:0000247 - !!omap - id: s_0767 - name: glycerol 3-phosphate @@ -5129,6 +5707,7 @@ - annotation: !!omap - chebi: CHEBI:57597 - kegg.compound: C00093 + - sbo: SBO:0000247 - !!omap - id: s_0769 - name: glycerol 3-phosphate @@ -5138,6 +5717,7 @@ - annotation: !!omap - chebi: CHEBI:57597 - kegg.compound: C00093 + - sbo: SBO:0000247 - !!omap - id: s_0770 - name: glycerol 3-phosphate @@ -5147,6 +5727,7 @@ - annotation: !!omap - chebi: CHEBI:57597 - kegg.compound: C00093 + - sbo: SBO:0000247 - !!omap - id: s_0771 - name: glycerone @@ -5156,6 +5737,7 @@ - annotation: !!omap - chebi: CHEBI:16016 - kegg.compound: C00184 + - sbo: SBO:0000247 - !!omap - id: s_0773 - name: glycogen @@ -5164,6 +5746,7 @@ - annotation: !!omap - chebi: CHEBI:28087 - kegg.compound: C00182 + - sbo: SBO:0000247 - !!omap - id: s_0774 - name: glycogen @@ -5172,6 +5755,7 @@ - annotation: !!omap - chebi: CHEBI:28087 - kegg.compound: C00182 + - sbo: SBO:0000247 - !!omap - id: s_0775 - name: glycolaldehyde @@ -5181,6 +5765,7 @@ - annotation: !!omap - chebi: CHEBI:17071 - kegg.compound: C00266 + - sbo: SBO:0000247 - !!omap - id: s_0776 - name: glycolaldehyde @@ -5190,6 +5775,7 @@ - annotation: !!omap - chebi: CHEBI:17071 - kegg.compound: C00266 + - sbo: SBO:0000247 - !!omap - id: s_0777 - name: glycolaldehyde @@ -5199,6 +5785,7 @@ - annotation: !!omap - chebi: CHEBI:17071 - kegg.compound: C00266 + - sbo: SBO:0000247 - !!omap - id: s_0779 - name: glyoxylate @@ -5208,6 +5795,7 @@ - annotation: !!omap - chebi: CHEBI:36655 - kegg.compound: C00048 + - sbo: SBO:0000247 - !!omap - id: s_0780 - name: glyoxylate @@ -5217,6 +5805,7 @@ - annotation: !!omap - chebi: CHEBI:36655 - kegg.compound: C00048 + - sbo: SBO:0000247 - !!omap - id: s_0781 - name: glyoxylate @@ -5226,6 +5815,7 @@ - annotation: !!omap - chebi: CHEBI:36655 - kegg.compound: C00048 + - sbo: SBO:0000247 - !!omap - id: s_0782 - name: GMP @@ -5235,6 +5825,7 @@ - annotation: !!omap - chebi: CHEBI:58115 - kegg.compound: C00144 + - sbo: SBO:0000247 - !!omap - id: s_0783 - name: GMP @@ -5244,6 +5835,7 @@ - annotation: !!omap - chebi: CHEBI:58115 - kegg.compound: C00144 + - sbo: SBO:0000247 - !!omap - id: s_0785 - name: GTP @@ -5253,6 +5845,7 @@ - annotation: !!omap - chebi: CHEBI:57600 - kegg.compound: C00044 + - sbo: SBO:0000247 - !!omap - id: s_0786 - name: GTP @@ -5262,6 +5855,7 @@ - annotation: !!omap - chebi: CHEBI:57600 - kegg.compound: C00044 + - sbo: SBO:0000247 - !!omap - id: s_0787 - name: guanine @@ -5271,6 +5865,7 @@ - annotation: !!omap - chebi: CHEBI:16235 - kegg.compound: C00242 + - sbo: SBO:0000247 - !!omap - id: s_0788 - name: guanine @@ -5280,6 +5875,7 @@ - annotation: !!omap - chebi: CHEBI:16235 - kegg.compound: C00242 + - sbo: SBO:0000247 - !!omap - id: s_0789 - name: guanine @@ -5289,6 +5885,7 @@ - annotation: !!omap - chebi: CHEBI:16235 - kegg.compound: C00242 + - sbo: SBO:0000247 - !!omap - id: s_0790 - name: guanosine @@ -5298,6 +5895,7 @@ - annotation: !!omap - chebi: CHEBI:16750 - kegg.compound: C00387 + - sbo: SBO:0000247 - !!omap - id: s_0791 - name: guanosine @@ -5307,6 +5905,7 @@ - annotation: !!omap - chebi: CHEBI:16750 - kegg.compound: C00387 + - sbo: SBO:0000247 - !!omap - id: s_0792 - name: guanosine @@ -5316,6 +5915,7 @@ - annotation: !!omap - chebi: CHEBI:16750 - kegg.compound: C00387 + - sbo: SBO:0000247 - !!omap - id: s_0793 - name: H+ @@ -5325,6 +5925,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_0794 - name: H+ @@ -5334,6 +5935,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_0795 - name: H+ @@ -5343,6 +5945,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_0796 - name: H+ @@ -5352,6 +5955,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_0797 - name: H+ @@ -5361,6 +5965,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_0798 - name: H+ @@ -5370,6 +5975,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_0799 - name: H+ @@ -5379,6 +5985,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_0800 - name: H+ @@ -5388,6 +5995,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_0801 - name: H+ @@ -5397,6 +6005,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_0802 - name: H+ @@ -5406,6 +6015,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_0803 - name: H2O @@ -5415,6 +6025,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_0804 - name: H2O @@ -5424,6 +6035,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_0805 - name: H2O @@ -5433,6 +6045,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_0806 - name: H2O @@ -5442,6 +6055,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_0807 - name: H2O @@ -5451,6 +6065,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_0808 - name: H2O @@ -5460,6 +6075,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_0809 - name: H2O @@ -5469,6 +6085,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_0810 - name: H2O @@ -5478,6 +6095,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_0811 - name: heme a @@ -5487,6 +6105,7 @@ - annotation: !!omap - chebi: CHEBI:24479 - kegg.compound: C15670 + - sbo: SBO:0000247 - !!omap - id: s_0812 - name: heme o @@ -5496,6 +6115,7 @@ - annotation: !!omap - chebi: CHEBI:24480 - kegg.compound: C15672 + - sbo: SBO:0000247 - !!omap - id: s_0813 - name: henicosaprenyl diphosphate @@ -5504,6 +6124,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53032 + - sbo: SBO:0000247 - !!omap - id: s_0814 - name: heptadecaprenyl diphosphate @@ -5512,6 +6133,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53036 + - sbo: SBO:0000247 - !!omap - id: s_0815 - name: heptaprenyl diphosphate @@ -5521,6 +6143,7 @@ - annotation: !!omap - chebi: CHEBI:53046 - kegg.compound: C04216 + - sbo: SBO:0000247 - !!omap - id: s_0816 - name: hexacosanoyl-CoA @@ -5529,6 +6152,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52966 + - sbo: SBO:0000247 - !!omap - id: s_0817 - name: hexacosanoyl-CoA @@ -5537,6 +6161,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52966 + - sbo: SBO:0000247 - !!omap - id: s_0819 - name: hexacosanoyl-CoA @@ -5545,12 +6170,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52966 + - sbo: SBO:0000247 - !!omap - id: s_0823 - name: hexadec-2-enoyl-CoA - compartment: p - formula: C37H64N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_0825 - name: hexadecanal @@ -5560,6 +6188,7 @@ - annotation: !!omap - chebi: CHEBI:17600 - kegg.compound: C00517 + - sbo: SBO:0000247 - !!omap - id: s_0826 - name: hexadecanal @@ -5569,6 +6198,7 @@ - annotation: !!omap - chebi: CHEBI:17600 - kegg.compound: C00517 + - sbo: SBO:0000247 - !!omap - id: s_0829 - name: hexadecaprenyl diphosphate @@ -5577,6 +6207,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53037 + - sbo: SBO:0000247 - !!omap - id: s_0830 - name: hexaprenyl diphosphate @@ -5586,6 +6217,7 @@ - annotation: !!omap - chebi: CHEBI:53047 - kegg.compound: C01230 + - sbo: SBO:0000247 - !!omap - id: s_0831 - name: hexaprenyl diphosphate @@ -5595,6 +6227,7 @@ - annotation: !!omap - chebi: CHEBI:53047 - kegg.compound: C01230 + - sbo: SBO:0000247 - !!omap - id: s_0832 - name: His-tRNA(His) @@ -5604,6 +6237,7 @@ - annotation: !!omap - chebi: CHEBI:29155 - kegg.compound: C02988 + - sbo: SBO:0000247 - !!omap - id: s_0833 - name: His-tRNA(His) @@ -5613,6 +6247,7 @@ - annotation: !!omap - chebi: CHEBI:29155 - kegg.compound: C02988 + - sbo: SBO:0000247 - !!omap - id: s_0834 - name: homocitrate @@ -5622,6 +6257,7 @@ - annotation: !!omap - chebi: CHEBI:36457 - kegg.compound: C01251 + - sbo: SBO:0000247 - !!omap - id: s_0835 - name: homocitrate @@ -5631,6 +6267,7 @@ - annotation: !!omap - chebi: CHEBI:36457 - kegg.compound: C01251 + - sbo: SBO:0000247 - !!omap - id: s_0836 - name: homoisocitrate @@ -5640,6 +6277,7 @@ - annotation: !!omap - chebi: CHEBI:30904 - kegg.compound: C05662 + - sbo: SBO:0000247 - !!omap - id: s_0837 - name: hydrogen peroxide @@ -5649,6 +6287,7 @@ - annotation: !!omap - chebi: CHEBI:16240 - kegg.compound: C00027 + - sbo: SBO:0000247 - !!omap - id: s_0838 - name: hydrogen peroxide @@ -5658,6 +6297,7 @@ - annotation: !!omap - chebi: CHEBI:16240 - kegg.compound: C00027 + - sbo: SBO:0000247 - !!omap - id: s_0839 - name: hydrogen peroxide @@ -5667,6 +6307,7 @@ - annotation: !!omap - chebi: CHEBI:16240 - kegg.compound: C00027 + - sbo: SBO:0000247 - !!omap - id: s_0840 - name: hydrogen peroxide @@ -5676,6 +6317,7 @@ - annotation: !!omap - chebi: CHEBI:16240 - kegg.compound: C00027 + - sbo: SBO:0000247 - !!omap - id: s_0841 - name: hydrogen sulfide @@ -5685,6 +6327,7 @@ - annotation: !!omap - chebi: CHEBI:29919 - kegg.compound: C00283 + - sbo: SBO:0000247 - !!omap - id: s_0843 - name: hypoxanthine @@ -5694,6 +6337,7 @@ - annotation: !!omap - chebi: CHEBI:17368 - kegg.compound: C00262 + - sbo: SBO:0000247 - !!omap - id: s_0844 - name: hypoxanthine @@ -5703,6 +6347,7 @@ - annotation: !!omap - chebi: CHEBI:17368 - kegg.compound: C00262 + - sbo: SBO:0000247 - !!omap - id: s_0845 - name: icosaprenyl diphosphate @@ -5711,6 +6356,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53033 + - sbo: SBO:0000247 - !!omap - id: s_0846 - name: IDP @@ -5720,6 +6366,7 @@ - annotation: !!omap - chebi: CHEBI:58280 - kegg.compound: C00104 + - sbo: SBO:0000247 - !!omap - id: s_0847 - name: Ile-tRNA(Ile) @@ -5729,6 +6376,7 @@ - annotation: !!omap - chebi: CHEBI:29160 - kegg.compound: C03127 + - sbo: SBO:0000247 - !!omap - id: s_0848 - name: Ile-tRNA(Ile) @@ -5738,6 +6386,7 @@ - annotation: !!omap - chebi: CHEBI:29160 - kegg.compound: C03127 + - sbo: SBO:0000247 - !!omap - id: s_0849 - name: IMP @@ -5747,6 +6396,7 @@ - annotation: !!omap - chebi: CHEBI:58053 - kegg.compound: C00130 + - sbo: SBO:0000247 - !!omap - id: s_0850 - name: indol-3-ylacetaldehyde @@ -5756,6 +6406,7 @@ - annotation: !!omap - chebi: CHEBI:18086 - kegg.compound: C00637 + - sbo: SBO:0000247 - !!omap - id: s_0851 - name: indol-3-ylacetaldehyde @@ -5765,6 +6416,7 @@ - annotation: !!omap - chebi: CHEBI:18086 - kegg.compound: C00637 + - sbo: SBO:0000247 - !!omap - id: s_0852 - name: indol-3-ylacetaldehyde @@ -5774,6 +6426,7 @@ - annotation: !!omap - chebi: CHEBI:18086 - kegg.compound: C00637 + - sbo: SBO:0000247 - !!omap - id: s_0853 - name: indole-3-acetate @@ -5783,6 +6436,7 @@ - annotation: !!omap - chebi: CHEBI:30854 - kegg.compound: C00954 + - sbo: SBO:0000247 - !!omap - id: s_0854 - name: indole-3-acetate @@ -5792,6 +6446,7 @@ - annotation: !!omap - chebi: CHEBI:30854 - kegg.compound: C00954 + - sbo: SBO:0000247 - !!omap - id: s_0855 - name: indole-3-pyruvate @@ -5801,6 +6456,7 @@ - annotation: !!omap - chebi: CHEBI:17640 - kegg.compound: C00331 + - sbo: SBO:0000247 - !!omap - id: s_0856 - name: inosine @@ -5810,6 +6466,7 @@ - annotation: !!omap - chebi: CHEBI:17596 - kegg.compound: C00294 + - sbo: SBO:0000247 - !!omap - id: s_0857 - name: inosine @@ -5819,6 +6476,7 @@ - annotation: !!omap - chebi: CHEBI:17596 - kegg.compound: C00294 + - sbo: SBO:0000247 - !!omap - id: s_0859 - name: inositol phosphomannosylinositol phosphoceramide backbone @@ -5827,6 +6485,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62682 + - sbo: SBO:0000649 - !!omap - id: s_0861 - name: inositol phosphomannosylinositol phosphoceramide A (C24) @@ -5835,6 +6494,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60439 + - sbo: SBO:0000247 - !!omap - id: s_0862 - name: inositol phosphomannosylinositol phosphoceramide A (C24) @@ -5843,6 +6503,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60439 + - sbo: SBO:0000247 - !!omap - id: s_0863 - name: inositol phosphomannosylinositol phosphoceramide A (C24) @@ -5851,6 +6512,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60439 + - sbo: SBO:0000247 - !!omap - id: s_0864 - name: inositol phosphomannosylinositol phosphoceramide A (C26) @@ -5859,6 +6521,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62715 + - sbo: SBO:0000247 - !!omap - id: s_0865 - name: inositol phosphomannosylinositol phosphoceramide A (C26) @@ -5867,6 +6530,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62715 + - sbo: SBO:0000247 - !!omap - id: s_0866 - name: inositol phosphomannosylinositol phosphoceramide A (C26) @@ -5875,6 +6539,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62715 + - sbo: SBO:0000247 - !!omap - id: s_0867 - name: inositol phosphomannosylinositol phosphoceramide B (C24) @@ -5883,6 +6548,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60443 + - sbo: SBO:0000247 - !!omap - id: s_0868 - name: inositol phosphomannosylinositol phosphoceramide B (C24) @@ -5891,6 +6557,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60443 + - sbo: SBO:0000247 - !!omap - id: s_0869 - name: inositol phosphomannosylinositol phosphoceramide B (C24) @@ -5899,6 +6566,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60443 + - sbo: SBO:0000247 - !!omap - id: s_0870 - name: inositol phosphomannosylinositol phosphoceramide B (C26) @@ -5907,6 +6575,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62719 + - sbo: SBO:0000247 - !!omap - id: s_0871 - name: inositol phosphomannosylinositol phosphoceramide B (C26) @@ -5915,6 +6584,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62719 + - sbo: SBO:0000247 - !!omap - id: s_0872 - name: inositol phosphomannosylinositol phosphoceramide B (C26) @@ -5923,6 +6593,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62719 + - sbo: SBO:0000247 - !!omap - id: s_0873 - name: inositol phosphomannosylinositol phosphoceramide B' (C24) @@ -5931,6 +6602,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60441 + - sbo: SBO:0000247 - !!omap - id: s_0874 - name: inositol phosphomannosylinositol phosphoceramide B' (C24) @@ -5939,6 +6611,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60441 + - sbo: SBO:0000247 - !!omap - id: s_0875 - name: inositol phosphomannosylinositol phosphoceramide B' (C24) @@ -5947,6 +6620,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60441 + - sbo: SBO:0000247 - !!omap - id: s_0876 - name: inositol phosphomannosylinositol phosphoceramide B' (C26) @@ -5955,6 +6629,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62717 + - sbo: SBO:0000247 - !!omap - id: s_0877 - name: inositol phosphomannosylinositol phosphoceramide B' (C26) @@ -5963,6 +6638,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62717 + - sbo: SBO:0000247 - !!omap - id: s_0878 - name: inositol phosphomannosylinositol phosphoceramide B' (C26) @@ -5971,6 +6647,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62717 + - sbo: SBO:0000247 - !!omap - id: s_0879 - name: inositol phosphomannosylinositol phosphoceramide C (C24) @@ -5979,6 +6656,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60445 + - sbo: SBO:0000247 - !!omap - id: s_0880 - name: inositol phosphomannosylinositol phosphoceramide C (C24) @@ -5987,6 +6665,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60445 + - sbo: SBO:0000247 - !!omap - id: s_0881 - name: inositol phosphomannosylinositol phosphoceramide C (C24) @@ -5995,6 +6674,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60445 + - sbo: SBO:0000247 - !!omap - id: s_0882 - name: inositol phosphomannosylinositol phosphoceramide C (C26) @@ -6003,6 +6683,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53005 + - sbo: SBO:0000247 - !!omap - id: s_0883 - name: inositol phosphomannosylinositol phosphoceramide C (C26) @@ -6011,6 +6692,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53005 + - sbo: SBO:0000247 - !!omap - id: s_0884 - name: inositol phosphomannosylinositol phosphoceramide C (C26) @@ -6019,6 +6701,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53005 + - sbo: SBO:0000247 - !!omap - id: s_0885 - name: inositol phosphomannosylinositol phosphoceramide D (C24) @@ -6027,6 +6710,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60446 + - sbo: SBO:0000247 - !!omap - id: s_0886 - name: inositol phosphomannosylinositol phosphoceramide D (C24) @@ -6035,6 +6719,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60446 + - sbo: SBO:0000247 - !!omap - id: s_0887 - name: inositol phosphomannosylinositol phosphoceramide D (C24) @@ -6043,6 +6728,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60446 + - sbo: SBO:0000247 - !!omap - id: s_0888 - name: inositol phosphomannosylinositol phosphoceramide D (C26) @@ -6051,6 +6737,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62684 + - sbo: SBO:0000247 - !!omap - id: s_0889 - name: inositol phosphomannosylinositol phosphoceramide D (C26) @@ -6059,6 +6746,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62684 + - sbo: SBO:0000247 - !!omap - id: s_0890 - name: inositol phosphomannosylinositol phosphoceramide D (C26) @@ -6067,6 +6755,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62684 + - sbo: SBO:0000247 - !!omap - id: s_0892 - name: inositol-P-ceramide backbone @@ -6074,6 +6763,7 @@ - formula: C6H12NO10P - annotation: !!omap - chebi: CHEBI:60245 + - sbo: SBO:0000649 - !!omap - id: s_0894 - name: inositol-P-ceramide A (C24) @@ -6082,6 +6772,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60402 + - sbo: SBO:0000247 - !!omap - id: s_0895 - name: inositol-P-ceramide A (C24) @@ -6090,6 +6781,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60402 + - sbo: SBO:0000247 - !!omap - id: s_0896 - name: inositol-P-ceramide A (C24) @@ -6098,6 +6790,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60402 + - sbo: SBO:0000247 - !!omap - id: s_0897 - name: inositol-P-ceramide A (C26) @@ -6106,6 +6799,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60405 + - sbo: SBO:0000247 - !!omap - id: s_0898 - name: inositol-P-ceramide A (C26) @@ -6114,6 +6808,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60405 + - sbo: SBO:0000247 - !!omap - id: s_0899 - name: inositol-P-ceramide A (C26) @@ -6122,6 +6817,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60405 + - sbo: SBO:0000247 - !!omap - id: s_0900 - name: inositol-P-ceramide B (C24) @@ -6130,6 +6826,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60410 + - sbo: SBO:0000247 - !!omap - id: s_0901 - name: inositol-P-ceramide B (C24) @@ -6138,6 +6835,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60410 + - sbo: SBO:0000247 - !!omap - id: s_0902 - name: inositol-P-ceramide B (C24) @@ -6146,6 +6844,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60410 + - sbo: SBO:0000247 - !!omap - id: s_0903 - name: inositol-P-ceramide B (C26) @@ -6154,6 +6853,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60412 + - sbo: SBO:0000247 - !!omap - id: s_0904 - name: inositol-P-ceramide B (C26) @@ -6162,6 +6862,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60412 + - sbo: SBO:0000247 - !!omap - id: s_0905 - name: inositol-P-ceramide B (C26) @@ -6170,6 +6871,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60412 + - sbo: SBO:0000247 - !!omap - id: s_0906 - name: inositol-P-ceramide B' (C24) @@ -6178,6 +6880,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60406 + - sbo: SBO:0000247 - !!omap - id: s_0907 - name: inositol-P-ceramide B' (C24) @@ -6186,6 +6889,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60406 + - sbo: SBO:0000247 - !!omap - id: s_0908 - name: inositol-P-ceramide B' (C24) @@ -6194,6 +6898,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60406 + - sbo: SBO:0000247 - !!omap - id: s_0909 - name: inositol-P-ceramide B' (C26) @@ -6202,6 +6907,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60409 + - sbo: SBO:0000247 - !!omap - id: s_0910 - name: inositol-P-ceramide B' (C26) @@ -6210,6 +6916,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60409 + - sbo: SBO:0000247 - !!omap - id: s_0911 - name: inositol-P-ceramide B' (C26) @@ -6218,6 +6925,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60409 + - sbo: SBO:0000247 - !!omap - id: s_0912 - name: inositol-P-ceramide C (C24) @@ -6226,6 +6934,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60413 + - sbo: SBO:0000247 - !!omap - id: s_0913 - name: inositol-P-ceramide C (C24) @@ -6234,6 +6943,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60413 + - sbo: SBO:0000247 - !!omap - id: s_0914 - name: inositol-P-ceramide C (C24) @@ -6242,6 +6952,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60413 + - sbo: SBO:0000247 - !!omap - id: s_0915 - name: inositol-P-ceramide C (C26) @@ -6250,6 +6961,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53004 + - sbo: SBO:0000247 - !!omap - id: s_0916 - name: inositol-P-ceramide C (C26) @@ -6258,6 +6970,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53004 + - sbo: SBO:0000247 - !!omap - id: s_0917 - name: inositol-P-ceramide C (C26) @@ -6266,6 +6979,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53004 + - sbo: SBO:0000247 - !!omap - id: s_0918 - name: inositol-P-ceramide D (C24) @@ -6274,6 +6988,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60414 + - sbo: SBO:0000247 - !!omap - id: s_0919 - name: inositol-P-ceramide D (C24) @@ -6282,6 +6997,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60414 + - sbo: SBO:0000247 - !!omap - id: s_0920 - name: inositol-P-ceramide D (C24) @@ -6290,6 +7006,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60414 + - sbo: SBO:0000247 - !!omap - id: s_0921 - name: inositol-P-ceramide D (C26) @@ -6298,6 +7015,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60415 + - sbo: SBO:0000247 - !!omap - id: s_0922 - name: inositol-P-ceramide D (C26) @@ -6306,6 +7024,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60415 + - sbo: SBO:0000247 - !!omap - id: s_0923 - name: inositol-P-ceramide D (C26) @@ -6314,6 +7033,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60415 + - sbo: SBO:0000247 - !!omap - id: s_0924 - name: iron(2+) @@ -6323,6 +7043,7 @@ - annotation: !!omap - chebi: CHEBI:29033 - kegg.compound: C14818 + - sbo: SBO:0000247 - !!omap - id: s_0925 - name: iron(2+) @@ -6332,6 +7053,7 @@ - annotation: !!omap - chebi: CHEBI:29033 - kegg.compound: C14818 + - sbo: SBO:0000247 - !!omap - id: s_0926 - name: iron(2+) @@ -6341,6 +7063,7 @@ - annotation: !!omap - chebi: CHEBI:29033 - kegg.compound: C14818 + - sbo: SBO:0000247 - !!omap - id: s_0927 - name: isoamyl acetate @@ -6350,6 +7073,7 @@ - annotation: !!omap - chebi: CHEBI:31725 - kegg.compound: C12296 + - sbo: SBO:0000247 - !!omap - id: s_0928 - name: isoamyl acetate @@ -6359,6 +7083,7 @@ - annotation: !!omap - chebi: CHEBI:31725 - kegg.compound: C12296 + - sbo: SBO:0000247 - !!omap - id: s_0929 - name: isoamylol @@ -6368,6 +7093,7 @@ - annotation: !!omap - chebi: CHEBI:15837 - kegg.compound: C07328 + - sbo: SBO:0000247 - !!omap - id: s_0930 - name: isoamylol @@ -6377,6 +7103,7 @@ - annotation: !!omap - chebi: CHEBI:15837 - kegg.compound: C07328 + - sbo: SBO:0000247 - !!omap - id: s_0931 - name: isoamylol @@ -6386,6 +7113,7 @@ - annotation: !!omap - chebi: CHEBI:15837 - kegg.compound: C07328 + - sbo: SBO:0000247 - !!omap - id: s_0932 - name: isobutanol @@ -6395,6 +7123,7 @@ - annotation: !!omap - chebi: CHEBI:46645 - kegg.compound: C14710 + - sbo: SBO:0000247 - !!omap - id: s_0933 - name: isobutanol @@ -6404,6 +7133,7 @@ - annotation: !!omap - chebi: CHEBI:46645 - kegg.compound: C14710 + - sbo: SBO:0000247 - !!omap - id: s_0934 - name: isobutanol @@ -6413,6 +7143,7 @@ - annotation: !!omap - chebi: CHEBI:46645 - kegg.compound: C14710 + - sbo: SBO:0000247 - !!omap - id: s_0935 - name: isobutyl acetate @@ -6421,6 +7152,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:50569 + - sbo: SBO:0000247 - !!omap - id: s_0936 - name: isobutyl acetate @@ -6429,6 +7161,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:50569 + - sbo: SBO:0000247 - !!omap - id: s_0937 - name: isobutyraldehyde @@ -6437,6 +7170,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:48943 + - sbo: SBO:0000247 - !!omap - id: s_0938 - name: isobutyraldehyde @@ -6445,6 +7179,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:48943 + - sbo: SBO:0000247 - !!omap - id: s_0939 - name: isobutyraldehyde @@ -6453,6 +7188,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:48943 + - sbo: SBO:0000247 - !!omap - id: s_0940 - name: isocitrate @@ -6462,6 +7198,7 @@ - annotation: !!omap - chebi: CHEBI:16087 - kegg.compound: C00311 + - sbo: SBO:0000247 - !!omap - id: s_0941 - name: isocitrate @@ -6471,6 +7208,7 @@ - annotation: !!omap - chebi: CHEBI:16087 - kegg.compound: C00311 + - sbo: SBO:0000247 - !!omap - id: s_0942 - name: isocitrate @@ -6480,6 +7218,7 @@ - annotation: !!omap - chebi: CHEBI:16087 - kegg.compound: C00311 + - sbo: SBO:0000247 - !!omap - id: s_0943 - name: isopentenyl diphosphate @@ -6489,6 +7228,7 @@ - annotation: !!omap - chebi: CHEBI:128769 - kegg.compound: C00129 + - sbo: SBO:0000247 - !!omap - id: s_0944 - name: isopentenyl diphosphate @@ -6498,6 +7238,7 @@ - annotation: !!omap - chebi: CHEBI:128769 - kegg.compound: C00129 + - sbo: SBO:0000247 - !!omap - id: s_0945 - name: isopentenyl diphosphate @@ -6507,6 +7248,7 @@ - annotation: !!omap - chebi: CHEBI:128769 - kegg.compound: C00129 + - sbo: SBO:0000247 - !!omap - id: s_0946 - name: itaconate @@ -6516,6 +7258,7 @@ - annotation: !!omap - chebi: CHEBI:17240 - kegg.compound: C00490 + - sbo: SBO:0000247 - !!omap - id: s_0949 - name: itaconyl-CoA @@ -6525,6 +7268,7 @@ - annotation: !!omap - chebi: CHEBI:57381 - kegg.compound: C00531 + - sbo: SBO:0000247 - !!omap - id: s_0950 - name: ITP @@ -6534,6 +7278,7 @@ - annotation: !!omap - chebi: CHEBI:61402 - kegg.compound: C00081 + - sbo: SBO:0000247 - !!omap - id: s_0951 - name: keto-phenylpyruvate @@ -6543,6 +7288,7 @@ - annotation: !!omap - chebi: CHEBI:18005 - kegg.compound: C00166 + - sbo: SBO:0000247 - !!omap - id: s_0952 - name: L-2-amino-3-oxobutanoate @@ -6552,6 +7298,7 @@ - annotation: !!omap - chebi: CHEBI:40673 - kegg.compound: C03508 + - sbo: SBO:0000247 - !!omap - id: s_0953 - name: L-2-aminoadipate @@ -6561,6 +7308,7 @@ - annotation: !!omap - chebi: CHEBI:58672 - kegg.compound: C00956 + - sbo: SBO:0000247 - !!omap - id: s_0954 - name: L-4-hydroxyglutamic semialdehyde @@ -6570,6 +7318,7 @@ - annotation: !!omap - chebi: CHEBI:27809 - kegg.compound: C05938 + - sbo: SBO:0000247 - !!omap - id: s_0955 - name: L-alanine @@ -6579,6 +7328,7 @@ - annotation: !!omap - chebi: CHEBI:16977 - kegg.compound: C00041 + - sbo: SBO:0000247 - !!omap - id: s_0956 - name: L-alanine @@ -6588,6 +7338,7 @@ - annotation: !!omap - chebi: CHEBI:16977 - kegg.compound: C00041 + - sbo: SBO:0000247 - !!omap - id: s_0957 - name: L-alanine @@ -6597,6 +7348,7 @@ - annotation: !!omap - chebi: CHEBI:16977 - kegg.compound: C00041 + - sbo: SBO:0000247 - !!omap - id: s_0958 - name: L-allothreonine @@ -6606,6 +7358,7 @@ - annotation: !!omap - chebi: CHEBI:28718 - kegg.compound: C05519 + - sbo: SBO:0000247 - !!omap - id: s_0959 - name: L-allysine @@ -6615,6 +7368,7 @@ - annotation: !!omap - chebi: CHEBI:17917 - kegg.compound: C04076 + - sbo: SBO:0000247 - !!omap - id: s_0960 - name: L-alpha-formylglycine @@ -6624,6 +7378,7 @@ - annotation: !!omap - chebi: CHEBI:58671 - kegg.compound: C11822 + - sbo: SBO:0000247 - !!omap - id: s_0961 - name: L-arabinitol @@ -6633,6 +7388,7 @@ - annotation: !!omap - chebi: CHEBI:18403 - kegg.compound: C00532 + - sbo: SBO:0000247 - !!omap - id: s_0962 - name: L-arabinitol @@ -6642,6 +7398,7 @@ - annotation: !!omap - chebi: CHEBI:18403 - kegg.compound: C00532 + - sbo: SBO:0000247 - !!omap - id: s_0963 - name: L-arabinose @@ -6651,6 +7408,7 @@ - annotation: !!omap - chebi: CHEBI:30849 - kegg.compound: C00259 + - sbo: SBO:0000247 - !!omap - id: s_0964 - name: L-arabinose @@ -6660,6 +7418,7 @@ - annotation: !!omap - chebi: CHEBI:30849 - kegg.compound: C00259 + - sbo: SBO:0000247 - !!omap - id: s_0965 - name: L-arginine @@ -6669,6 +7428,7 @@ - annotation: !!omap - chebi: CHEBI:32682 - kegg.compound: C00062 + - sbo: SBO:0000247 - !!omap - id: s_0966 - name: L-arginine @@ -6678,6 +7438,7 @@ - annotation: !!omap - chebi: CHEBI:32682 - kegg.compound: C00062 + - sbo: SBO:0000247 - !!omap - id: s_0967 - name: L-arginine @@ -6687,6 +7448,7 @@ - annotation: !!omap - chebi: CHEBI:32682 - kegg.compound: C00062 + - sbo: SBO:0000247 - !!omap - id: s_0968 - name: L-arginine @@ -6696,6 +7458,7 @@ - annotation: !!omap - chebi: CHEBI:32682 - kegg.compound: C00062 + - sbo: SBO:0000247 - !!omap - id: s_0969 - name: L-asparagine @@ -6705,6 +7468,7 @@ - annotation: !!omap - chebi: CHEBI:17196 - kegg.compound: C00152 + - sbo: SBO:0000247 - !!omap - id: s_0970 - name: L-asparagine @@ -6714,6 +7478,7 @@ - annotation: !!omap - chebi: CHEBI:17196 - kegg.compound: C00152 + - sbo: SBO:0000247 - !!omap - id: s_0971 - name: L-asparagine @@ -6723,6 +7488,7 @@ - annotation: !!omap - chebi: CHEBI:17196 - kegg.compound: C00152 + - sbo: SBO:0000247 - !!omap - id: s_0972 - name: L-asparagine @@ -6732,6 +7498,7 @@ - annotation: !!omap - chebi: CHEBI:17196 - kegg.compound: C00152 + - sbo: SBO:0000247 - !!omap - id: s_0973 - name: L-aspartate @@ -6741,6 +7508,7 @@ - annotation: !!omap - chebi: CHEBI:29991 - kegg.compound: C00049 + - sbo: SBO:0000247 - !!omap - id: s_0974 - name: L-aspartate @@ -6750,6 +7518,7 @@ - annotation: !!omap - chebi: CHEBI:29991 - kegg.compound: C00049 + - sbo: SBO:0000247 - !!omap - id: s_0975 - name: L-aspartate @@ -6759,6 +7528,7 @@ - annotation: !!omap - chebi: CHEBI:29991 - kegg.compound: C00049 + - sbo: SBO:0000247 - !!omap - id: s_0976 - name: L-aspartate @@ -6768,6 +7538,7 @@ - annotation: !!omap - chebi: CHEBI:29991 - kegg.compound: C00049 + - sbo: SBO:0000247 - !!omap - id: s_0977 - name: L-aspartate @@ -6777,6 +7548,7 @@ - annotation: !!omap - chebi: CHEBI:29991 - kegg.compound: C00049 + - sbo: SBO:0000247 - !!omap - id: s_0978 - name: L-aspartate 4-semialdehyde @@ -6786,6 +7558,7 @@ - annotation: !!omap - chebi: CHEBI:18051 - kegg.compound: C00441 + - sbo: SBO:0000247 - !!omap - id: s_0979 - name: L-citrulline @@ -6795,6 +7568,7 @@ - annotation: !!omap - chebi: CHEBI:16349 - kegg.compound: C00327 + - sbo: SBO:0000247 - !!omap - id: s_0980 - name: L-cystathionine @@ -6804,6 +7578,7 @@ - annotation: !!omap - chebi: CHEBI:17482 - kegg.compound: C02291 + - sbo: SBO:0000247 - !!omap - id: s_0981 - name: L-cysteine @@ -6813,6 +7588,7 @@ - annotation: !!omap - chebi: CHEBI:17561 - kegg.compound: C00097 + - sbo: SBO:0000247 - !!omap - id: s_0982 - name: L-cysteine @@ -6822,6 +7598,7 @@ - annotation: !!omap - chebi: CHEBI:17561 - kegg.compound: C00097 + - sbo: SBO:0000247 - !!omap - id: s_0983 - name: L-cysteinylglycine @@ -6831,6 +7608,7 @@ - annotation: !!omap - chebi: CHEBI:4047 - kegg.compound: C01419 + - sbo: SBO:0000247 - !!omap - id: s_0984 - name: L-cystine @@ -6840,6 +7618,7 @@ - annotation: !!omap - chebi: CHEBI:16283 - kegg.compound: C00491 + - sbo: SBO:0000247 - !!omap - id: s_0985 - name: L-cystine @@ -6849,6 +7628,7 @@ - annotation: !!omap - chebi: CHEBI:16283 - kegg.compound: C00491 + - sbo: SBO:0000247 - !!omap - id: s_0986 - name: L-gamma-glutamyl phosphate @@ -6858,6 +7638,7 @@ - annotation: !!omap - chebi: CHEBI:58274 - kegg.compound: C03287 + - sbo: SBO:0000247 - !!omap - id: s_0987 - name: L-gamma-glutamyl-L-alanine @@ -6867,6 +7648,7 @@ - annotation: !!omap - chebi: CHEBI:50619 - kegg.compound: C03738 + - sbo: SBO:0000247 - !!omap - id: s_0988 - name: L-gamma-glutamyl-L-cysteine @@ -6876,6 +7658,7 @@ - annotation: !!omap - chebi: CHEBI:58173 - kegg.compound: C00669 + - sbo: SBO:0000247 - !!omap - id: s_0989 - name: L-glucitol @@ -6885,6 +7668,7 @@ - annotation: !!omap - chebi: CHEBI:28789 - kegg.compound: C01722 + - sbo: SBO:0000247 - !!omap - id: s_0990 - name: L-glucitol @@ -6894,6 +7678,7 @@ - annotation: !!omap - chebi: CHEBI:28789 - kegg.compound: C01722 + - sbo: SBO:0000247 - !!omap - id: s_0991 - name: L-glutamate @@ -6903,6 +7688,7 @@ - annotation: !!omap - chebi: CHEBI:29985 - kegg.compound: C00025 + - sbo: SBO:0000247 - !!omap - id: s_0992 - name: L-glutamate @@ -6912,6 +7698,7 @@ - annotation: !!omap - chebi: CHEBI:29985 - kegg.compound: C00025 + - sbo: SBO:0000247 - !!omap - id: s_0993 - name: L-glutamate @@ -6921,6 +7708,7 @@ - annotation: !!omap - chebi: CHEBI:29985 - kegg.compound: C00025 + - sbo: SBO:0000247 - !!omap - id: s_0994 - name: L-glutamate @@ -6930,6 +7718,7 @@ - annotation: !!omap - chebi: CHEBI:29985 - kegg.compound: C00025 + - sbo: SBO:0000247 - !!omap - id: s_0995 - name: L-glutamate @@ -6939,6 +7728,7 @@ - annotation: !!omap - chebi: CHEBI:29985 - kegg.compound: C00025 + - sbo: SBO:0000247 - !!omap - id: s_0996 - name: L-glutamate @@ -6948,6 +7738,7 @@ - annotation: !!omap - chebi: CHEBI:29985 - kegg.compound: C00025 + - sbo: SBO:0000247 - !!omap - id: s_0997 - name: L-glutamic 5-semialdehyde @@ -6957,6 +7748,7 @@ - annotation: !!omap - chebi: CHEBI:17232 - kegg.compound: C01165 + - sbo: SBO:0000247 - !!omap - id: s_0999 - name: L-glutamine @@ -6966,6 +7758,7 @@ - annotation: !!omap - chebi: CHEBI:18050 - kegg.compound: C00064 + - sbo: SBO:0000247 - !!omap - id: s_1000 - name: L-glutamine @@ -6975,6 +7768,7 @@ - annotation: !!omap - chebi: CHEBI:18050 - kegg.compound: C00064 + - sbo: SBO:0000247 - !!omap - id: s_1001 - name: L-glutamine @@ -6984,6 +7778,7 @@ - annotation: !!omap - chebi: CHEBI:18050 - kegg.compound: C00064 + - sbo: SBO:0000247 - !!omap - id: s_1002 - name: L-glutamine @@ -6993,6 +7788,7 @@ - annotation: !!omap - chebi: CHEBI:18050 - kegg.compound: C00064 + - sbo: SBO:0000247 - !!omap - id: s_1003 - name: L-glycine @@ -7002,6 +7798,7 @@ - annotation: !!omap - chebi: CHEBI:15428 - kegg.compound: C00037 + - sbo: SBO:0000247 - !!omap - id: s_1004 - name: L-glycine @@ -7011,6 +7808,7 @@ - annotation: !!omap - chebi: CHEBI:15428 - kegg.compound: C00037 + - sbo: SBO:0000247 - !!omap - id: s_1005 - name: L-glycine @@ -7020,6 +7818,7 @@ - annotation: !!omap - chebi: CHEBI:15428 - kegg.compound: C00037 + - sbo: SBO:0000247 - !!omap - id: s_1006 - name: L-histidine @@ -7029,6 +7828,7 @@ - annotation: !!omap - chebi: CHEBI:15971 - kegg.compound: C00135 + - sbo: SBO:0000247 - !!omap - id: s_1007 - name: L-histidine @@ -7038,6 +7838,7 @@ - annotation: !!omap - chebi: CHEBI:15971 - kegg.compound: C00135 + - sbo: SBO:0000247 - !!omap - id: s_1008 - name: L-histidine @@ -7047,6 +7848,7 @@ - annotation: !!omap - chebi: CHEBI:15971 - kegg.compound: C00135 + - sbo: SBO:0000247 - !!omap - id: s_1009 - name: L-histidine @@ -7056,6 +7858,7 @@ - annotation: !!omap - chebi: CHEBI:15971 - kegg.compound: C00135 + - sbo: SBO:0000247 - !!omap - id: s_1010 - name: L-histidinol @@ -7065,6 +7868,7 @@ - annotation: !!omap - chebi: CHEBI:57699 - kegg.compound: C00860 + - sbo: SBO:0000247 - !!omap - id: s_1011 - name: L-histidinol phosphate @@ -7074,6 +7878,7 @@ - annotation: !!omap - chebi: CHEBI:57980 - kegg.compound: C01100 + - sbo: SBO:0000247 - !!omap - id: s_1012 - name: L-homocysteine @@ -7083,6 +7888,7 @@ - annotation: !!omap - chebi: CHEBI:17588 - kegg.compound: C00155 + - sbo: SBO:0000247 - !!omap - id: s_1014 - name: L-homoserine @@ -7092,6 +7898,7 @@ - annotation: !!omap - chebi: CHEBI:15699 - kegg.compound: C00263 + - sbo: SBO:0000247 - !!omap - id: s_1015 - name: L-homoserine @@ -7101,6 +7908,7 @@ - annotation: !!omap - chebi: CHEBI:15699 - kegg.compound: C00263 + - sbo: SBO:0000247 - !!omap - id: s_1016 - name: L-isoleucine @@ -7110,6 +7918,7 @@ - annotation: !!omap - chebi: CHEBI:17191 - kegg.compound: C00407 + - sbo: SBO:0000247 - !!omap - id: s_1017 - name: L-isoleucine @@ -7119,6 +7928,7 @@ - annotation: !!omap - chebi: CHEBI:17191 - kegg.compound: C00407 + - sbo: SBO:0000247 - !!omap - id: s_1018 - name: L-isoleucine @@ -7128,6 +7938,7 @@ - annotation: !!omap - chebi: CHEBI:17191 - kegg.compound: C00407 + - sbo: SBO:0000247 - !!omap - id: s_1019 - name: L-isoleucine @@ -7137,6 +7948,7 @@ - annotation: !!omap - chebi: CHEBI:17191 - kegg.compound: C00407 + - sbo: SBO:0000247 - !!omap - id: s_1020 - name: L-kynurenine @@ -7146,6 +7958,7 @@ - annotation: !!omap - chebi: CHEBI:16946 - kegg.compound: C00328 + - sbo: SBO:0000247 - !!omap - id: s_1021 - name: L-leucine @@ -7155,6 +7968,7 @@ - annotation: !!omap - chebi: CHEBI:15603 - kegg.compound: C00123 + - sbo: SBO:0000247 - !!omap - id: s_1022 - name: L-leucine @@ -7164,6 +7978,7 @@ - annotation: !!omap - chebi: CHEBI:15603 - kegg.compound: C00123 + - sbo: SBO:0000247 - !!omap - id: s_1023 - name: L-leucine @@ -7173,6 +7988,7 @@ - annotation: !!omap - chebi: CHEBI:15603 - kegg.compound: C00123 + - sbo: SBO:0000247 - !!omap - id: s_1024 - name: L-leucine @@ -7182,6 +7998,7 @@ - annotation: !!omap - chebi: CHEBI:15603 - kegg.compound: C00123 + - sbo: SBO:0000247 - !!omap - id: s_1025 - name: L-lysine @@ -7191,6 +8008,7 @@ - annotation: !!omap - chebi: CHEBI:32551 - kegg.compound: C00047 + - sbo: SBO:0000247 - !!omap - id: s_1026 - name: L-lysine @@ -7200,6 +8018,7 @@ - annotation: !!omap - chebi: CHEBI:32551 - kegg.compound: C00047 + - sbo: SBO:0000247 - !!omap - id: s_1027 - name: L-lysine @@ -7209,6 +8028,7 @@ - annotation: !!omap - chebi: CHEBI:32551 - kegg.compound: C00047 + - sbo: SBO:0000247 - !!omap - id: s_1028 - name: L-lysine @@ -7218,6 +8038,7 @@ - annotation: !!omap - chebi: CHEBI:32551 - kegg.compound: C00047 + - sbo: SBO:0000247 - !!omap - id: s_1029 - name: L-methionine @@ -7227,6 +8048,7 @@ - annotation: !!omap - chebi: CHEBI:16643 - kegg.compound: C00073 + - sbo: SBO:0000247 - !!omap - id: s_1030 - name: L-methionine @@ -7236,6 +8058,7 @@ - annotation: !!omap - chebi: CHEBI:16643 - kegg.compound: C00073 + - sbo: SBO:0000247 - !!omap - id: s_1031 - name: L-methionine @@ -7245,6 +8068,7 @@ - annotation: !!omap - chebi: CHEBI:16643 - kegg.compound: C00073 + - sbo: SBO:0000247 - !!omap - id: s_1032 - name: L-phenylalanine @@ -7254,6 +8078,7 @@ - annotation: !!omap - chebi: CHEBI:17295 - kegg.compound: C00079 + - sbo: SBO:0000247 - !!omap - id: s_1033 - name: L-phenylalanine @@ -7263,6 +8088,7 @@ - annotation: !!omap - chebi: CHEBI:17295 - kegg.compound: C00079 + - sbo: SBO:0000247 - !!omap - id: s_1034 - name: L-phenylalanine @@ -7272,6 +8098,7 @@ - annotation: !!omap - chebi: CHEBI:17295 - kegg.compound: C00079 + - sbo: SBO:0000247 - !!omap - id: s_1035 - name: L-proline @@ -7281,6 +8108,7 @@ - annotation: !!omap - chebi: CHEBI:17203 - kegg.compound: C00148 + - sbo: SBO:0000247 - !!omap - id: s_1036 - name: L-proline @@ -7290,6 +8118,7 @@ - annotation: !!omap - chebi: CHEBI:17203 - kegg.compound: C00148 + - sbo: SBO:0000247 - !!omap - id: s_1037 - name: L-proline @@ -7299,6 +8128,7 @@ - annotation: !!omap - chebi: CHEBI:17203 - kegg.compound: C00148 + - sbo: SBO:0000247 - !!omap - id: s_1038 - name: L-saccharopine @@ -7308,6 +8138,7 @@ - annotation: !!omap - chebi: CHEBI:57951 - kegg.compound: C00449 + - sbo: SBO:0000247 - !!omap - id: s_1039 - name: L-serine @@ -7317,6 +8148,7 @@ - annotation: !!omap - chebi: CHEBI:17115 - kegg.compound: C00065 + - sbo: SBO:0000247 - !!omap - id: s_1040 - name: L-serine @@ -7326,6 +8158,7 @@ - annotation: !!omap - chebi: CHEBI:17115 - kegg.compound: C00065 + - sbo: SBO:0000247 - !!omap - id: s_1041 - name: L-serine @@ -7335,6 +8168,7 @@ - annotation: !!omap - chebi: CHEBI:17115 - kegg.compound: C00065 + - sbo: SBO:0000247 - !!omap - id: s_1042 - name: L-serine @@ -7344,6 +8178,7 @@ - annotation: !!omap - chebi: CHEBI:17115 - kegg.compound: C00065 + - sbo: SBO:0000247 - !!omap - id: s_1043 - name: L-sorbose @@ -7353,6 +8188,7 @@ - annotation: !!omap - chebi: CHEBI:17266 - kegg.compound: C00247 + - sbo: SBO:0000247 - !!omap - id: s_1044 - name: L-sorbose @@ -7362,6 +8198,7 @@ - annotation: !!omap - chebi: CHEBI:17266 - kegg.compound: C00247 + - sbo: SBO:0000247 - !!omap - id: s_1045 - name: L-threonine @@ -7371,6 +8208,7 @@ - annotation: !!omap - chebi: CHEBI:16857 - kegg.compound: C00188 + - sbo: SBO:0000247 - !!omap - id: s_1046 - name: L-threonine @@ -7380,6 +8218,7 @@ - annotation: !!omap - chebi: CHEBI:16857 - kegg.compound: C00188 + - sbo: SBO:0000247 - !!omap - id: s_1047 - name: L-threonine @@ -7389,6 +8228,7 @@ - annotation: !!omap - chebi: CHEBI:16857 - kegg.compound: C00188 + - sbo: SBO:0000247 - !!omap - id: s_1048 - name: L-tryptophan @@ -7398,6 +8238,7 @@ - annotation: !!omap - chebi: CHEBI:16828 - kegg.compound: C00078 + - sbo: SBO:0000247 - !!omap - id: s_1049 - name: L-tryptophan @@ -7407,6 +8248,7 @@ - annotation: !!omap - chebi: CHEBI:16828 - kegg.compound: C00078 + - sbo: SBO:0000247 - !!omap - id: s_1050 - name: L-tryptophan @@ -7416,6 +8258,7 @@ - annotation: !!omap - chebi: CHEBI:16828 - kegg.compound: C00078 + - sbo: SBO:0000247 - !!omap - id: s_1051 - name: L-tyrosine @@ -7425,6 +8268,7 @@ - annotation: !!omap - chebi: CHEBI:17895 - kegg.compound: C00082 + - sbo: SBO:0000247 - !!omap - id: s_1052 - name: L-tyrosine @@ -7434,6 +8278,7 @@ - annotation: !!omap - chebi: CHEBI:17895 - kegg.compound: C00082 + - sbo: SBO:0000247 - !!omap - id: s_1053 - name: L-tyrosine @@ -7443,6 +8288,7 @@ - annotation: !!omap - chebi: CHEBI:17895 - kegg.compound: C00082 + - sbo: SBO:0000247 - !!omap - id: s_1054 - name: L-tyrosine @@ -7452,6 +8298,7 @@ - annotation: !!omap - chebi: CHEBI:17895 - kegg.compound: C00082 + - sbo: SBO:0000247 - !!omap - id: s_1055 - name: L-tyrosine @@ -7461,6 +8308,7 @@ - annotation: !!omap - chebi: CHEBI:17895 - kegg.compound: C00082 + - sbo: SBO:0000247 - !!omap - id: s_1056 - name: L-valine @@ -7470,6 +8318,7 @@ - annotation: !!omap - chebi: CHEBI:16414 - kegg.compound: C00183 + - sbo: SBO:0000247 - !!omap - id: s_1057 - name: L-valine @@ -7479,6 +8328,7 @@ - annotation: !!omap - chebi: CHEBI:16414 - kegg.compound: C00183 + - sbo: SBO:0000247 - !!omap - id: s_1058 - name: L-valine @@ -7488,6 +8338,7 @@ - annotation: !!omap - chebi: CHEBI:16414 - kegg.compound: C00183 + - sbo: SBO:0000247 - !!omap - id: s_1059 - name: lanosterol @@ -7497,6 +8348,7 @@ - annotation: !!omap - chebi: CHEBI:16521 - kegg.compound: C01724 + - sbo: SBO:0000247 - !!omap - id: s_1061 - name: lanosterol @@ -7506,6 +8358,7 @@ - annotation: !!omap - chebi: CHEBI:16521 - kegg.compound: C01724 + - sbo: SBO:0000247 - !!omap - id: s_1065 - name: laurate @@ -7515,6 +8368,7 @@ - annotation: !!omap - chebi: CHEBI:18262 - kegg.compound: C02679 + - sbo: SBO:0000247 - !!omap - id: s_1067 - name: laurate @@ -7524,6 +8378,7 @@ - annotation: !!omap - chebi: CHEBI:18262 - kegg.compound: C02679 + - sbo: SBO:0000247 - !!omap - id: s_1070 - name: laurate @@ -7533,6 +8388,7 @@ - annotation: !!omap - chebi: CHEBI:18262 - kegg.compound: C02679 + - sbo: SBO:0000247 - !!omap - id: s_1073 - name: lauroyl-CoA @@ -7542,6 +8398,7 @@ - annotation: !!omap - chebi: CHEBI:57375 - kegg.compound: C01832 + - sbo: SBO:0000247 - !!omap - id: s_1076 - name: lauroyl-CoA @@ -7551,6 +8408,7 @@ - annotation: !!omap - chebi: CHEBI:57375 - kegg.compound: C01832 + - sbo: SBO:0000247 - !!omap - id: s_1077 - name: Leu-tRNA(Leu) @@ -7560,6 +8418,7 @@ - annotation: !!omap - chebi: CHEBI:16624 - kegg.compound: C02047 + - sbo: SBO:0000247 - !!omap - id: s_1078 - name: Leu-tRNA(Leu) @@ -7569,6 +8428,7 @@ - annotation: !!omap - chebi: CHEBI:16624 - kegg.compound: C02047 + - sbo: SBO:0000247 - !!omap - id: s_1079 - name: leukotriene A4 @@ -7578,6 +8438,7 @@ - annotation: !!omap - chebi: CHEBI:57463 - kegg.compound: C00909 + - sbo: SBO:0000247 - !!omap - id: s_1080 - name: leukotriene A4 @@ -7587,6 +8448,7 @@ - annotation: !!omap - chebi: CHEBI:57463 - kegg.compound: C00909 + - sbo: SBO:0000247 - !!omap - id: s_1081 - name: leukotriene B4 @@ -7596,6 +8458,7 @@ - annotation: !!omap - chebi: CHEBI:57461 - kegg.compound: C02165 + - sbo: SBO:0000247 - !!omap - id: s_1082 - name: leukotriene B4 @@ -7605,6 +8468,7 @@ - annotation: !!omap - chebi: CHEBI:57461 - kegg.compound: C02165 + - sbo: SBO:0000247 - !!omap - id: s_1085 - name: lignoceric acid @@ -7614,6 +8478,7 @@ - annotation: !!omap - chebi: CHEBI:31014 - kegg.compound: C08320 + - sbo: SBO:0000247 - !!omap - id: s_1096 - name: lipid @@ -7622,6 +8487,7 @@ - annotation: !!omap - chebi: CHEBI:18059 - kegg.compound: C01356 + - sbo: SBO:0000649 - !!omap - id: s_1097 - name: lipoamide @@ -7631,6 +8497,7 @@ - annotation: !!omap - chebi: CHEBI:17460 - kegg.compound: C00248 + - sbo: SBO:0000247 - !!omap - id: s_1098 - name: lipoylprotein @@ -7640,6 +8507,7 @@ - annotation: !!omap - chebi: CHEBI:15804 - kegg.compound: C02051 + - sbo: SBO:0000247 - !!omap - id: s_1099 - name: Lys-tRNA(Lys) @@ -7649,6 +8517,7 @@ - annotation: !!omap - chebi: CHEBI:16047 - kegg.compound: C01931 + - sbo: SBO:0000247 - !!omap - id: s_1100 - name: Lys-tRNA(Lys) @@ -7658,6 +8527,7 @@ - annotation: !!omap - chebi: CHEBI:16047 - kegg.compound: C01931 + - sbo: SBO:0000247 - !!omap - id: s_1101 - name: malonyl-CoA @@ -7667,6 +8537,7 @@ - annotation: !!omap - chebi: CHEBI:57384 - kegg.compound: C00083 + - sbo: SBO:0000247 - !!omap - id: s_1104 - name: malonyl-CoA @@ -7676,6 +8547,7 @@ - annotation: !!omap - chebi: CHEBI:57384 - kegg.compound: C00083 + - sbo: SBO:0000247 - !!omap - id: s_1105 - name: maltose @@ -7685,6 +8557,7 @@ - annotation: !!omap - chebi: CHEBI:17306 - kegg.compound: C00208 + - sbo: SBO:0000247 - !!omap - id: s_1106 - name: maltose @@ -7694,6 +8567,7 @@ - annotation: !!omap - chebi: CHEBI:17306 - kegg.compound: C00208 + - sbo: SBO:0000247 - !!omap - id: s_1107 - name: mannan @@ -7702,6 +8576,7 @@ - annotation: !!omap - chebi: CHEBI:28808 - kegg.compound: C00464 + - sbo: SBO:0000247 - !!omap - id: s_1108 - name: mannan @@ -7710,6 +8585,7 @@ - annotation: !!omap - chebi: CHEBI:28808 - kegg.compound: C00464 + - sbo: SBO:0000247 - !!omap - id: s_1109 - name: mannose-(1D-myo-inositol 1-phosphate)2 @@ -7718,6 +8594,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60449 + - sbo: SBO:0000247 - !!omap - id: s_1110 - name: mannose-(1D-myo-inositol 1-phosphate)2 @@ -7726,6 +8603,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60449 + - sbo: SBO:0000247 - !!omap - id: s_1111 - name: mannose-1D-myo-inositol 1-phosphate @@ -7734,6 +8612,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60448 + - sbo: SBO:0000247 - !!omap - id: s_1112 - name: mannose-1D-myo-inositol 1-phosphate @@ -7742,6 +8621,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60448 + - sbo: SBO:0000247 - !!omap - id: s_1114 - name: mannosylinositol phosphorylceramide backbone @@ -7749,6 +8629,7 @@ - formula: C12H22NO15P - annotation: !!omap - chebi: CHEBI:25168 + - sbo: SBO:0000649 - !!omap - id: s_1116 - name: mannosylinositol phosphorylceramide A (C24) @@ -7757,6 +8638,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60416 + - sbo: SBO:0000247 - !!omap - id: s_1117 - name: mannosylinositol phosphorylceramide A (C24) @@ -7765,6 +8647,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60416 + - sbo: SBO:0000247 - !!omap - id: s_1118 - name: mannosylinositol phosphorylceramide A (C24) @@ -7773,6 +8656,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60416 + - sbo: SBO:0000247 - !!omap - id: s_1119 - name: mannosylinositol phosphorylceramide A (C26) @@ -7781,6 +8665,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62706 + - sbo: SBO:0000247 - !!omap - id: s_1120 - name: mannosylinositol phosphorylceramide A (C26) @@ -7789,6 +8674,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62706 + - sbo: SBO:0000247 - !!omap - id: s_1121 - name: mannosylinositol phosphorylceramide A (C26) @@ -7797,6 +8683,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62706 + - sbo: SBO:0000247 - !!omap - id: s_1122 - name: mannosylinositol phosphorylceramide B (C24) @@ -7805,6 +8692,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60420 + - sbo: SBO:0000247 - !!omap - id: s_1123 - name: mannosylinositol phosphorylceramide B (C24) @@ -7813,6 +8701,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60420 + - sbo: SBO:0000247 - !!omap - id: s_1124 - name: mannosylinositol phosphorylceramide B (C24) @@ -7821,6 +8710,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60420 + - sbo: SBO:0000247 - !!omap - id: s_1125 - name: mannosylinositol phosphorylceramide B (C26) @@ -7829,6 +8719,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62710 + - sbo: SBO:0000247 - !!omap - id: s_1126 - name: mannosylinositol phosphorylceramide B (C26) @@ -7837,6 +8728,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62710 + - sbo: SBO:0000247 - !!omap - id: s_1127 - name: mannosylinositol phosphorylceramide B (C26) @@ -7845,6 +8737,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62710 + - sbo: SBO:0000247 - !!omap - id: s_1128 - name: mannosylinositol phosphorylceramide B' (C24) @@ -7853,6 +8746,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60418 + - sbo: SBO:0000247 - !!omap - id: s_1129 - name: mannosylinositol phosphorylceramide B' (C24) @@ -7861,6 +8755,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60418 + - sbo: SBO:0000247 - !!omap - id: s_1130 - name: mannosylinositol phosphorylceramide B' (C24) @@ -7869,6 +8764,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60418 + - sbo: SBO:0000247 - !!omap - id: s_1131 - name: mannosylinositol phosphorylceramide B' (C26) @@ -7877,6 +8773,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62708 + - sbo: SBO:0000247 - !!omap - id: s_1132 - name: mannosylinositol phosphorylceramide B' (C26) @@ -7885,6 +8782,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62708 + - sbo: SBO:0000247 - !!omap - id: s_1133 - name: mannosylinositol phosphorylceramide B' (C26) @@ -7893,6 +8791,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62708 + - sbo: SBO:0000247 - !!omap - id: s_1134 - name: mannosylinositol phosphorylceramide C (C24) @@ -7901,6 +8800,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60422 + - sbo: SBO:0000247 - !!omap - id: s_1135 - name: mannosylinositol phosphorylceramide C (C24) @@ -7909,6 +8809,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60422 + - sbo: SBO:0000247 - !!omap - id: s_1136 - name: mannosylinositol phosphorylceramide C (C24) @@ -7917,6 +8818,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60422 + - sbo: SBO:0000247 - !!omap - id: s_1137 - name: mannosylinositol phosphorylceramide C (C26) @@ -7925,6 +8827,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62712 + - sbo: SBO:0000247 - !!omap - id: s_1138 - name: mannosylinositol phosphorylceramide C (C26) @@ -7933,6 +8836,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62712 + - sbo: SBO:0000247 - !!omap - id: s_1139 - name: mannosylinositol phosphorylceramide C (C26) @@ -7941,6 +8845,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62712 + - sbo: SBO:0000247 - !!omap - id: s_1140 - name: mannosylinositol phosphorylceramide D (C24) @@ -7949,6 +8854,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60435 + - sbo: SBO:0000247 - !!omap - id: s_1141 - name: mannosylinositol phosphorylceramide D (C24) @@ -7957,6 +8863,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60435 + - sbo: SBO:0000247 - !!omap - id: s_1142 - name: mannosylinositol phosphorylceramide D (C24) @@ -7965,6 +8872,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60435 + - sbo: SBO:0000247 - !!omap - id: s_1143 - name: mannosylinositol phosphorylceramide D (C26) @@ -7973,6 +8881,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62683 + - sbo: SBO:0000247 - !!omap - id: s_1144 - name: mannosylinositol phosphorylceramide D (C26) @@ -7981,6 +8890,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62683 + - sbo: SBO:0000247 - !!omap - id: s_1145 - name: mannosylinositol phosphorylceramide D (C26) @@ -7989,6 +8899,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62683 + - sbo: SBO:0000247 - !!omap - id: s_1148 - name: Met-tRNA(Met) @@ -7998,6 +8909,7 @@ - annotation: !!omap - chebi: CHEBI:16635 - kegg.compound: C02430 + - sbo: SBO:0000247 - !!omap - id: s_1149 - name: Met-tRNA(Met) @@ -8007,6 +8919,7 @@ - annotation: !!omap - chebi: CHEBI:16635 - kegg.compound: C02430 + - sbo: SBO:0000247 - !!omap - id: s_1150 - name: methanethiol @@ -8016,6 +8929,7 @@ - annotation: !!omap - chebi: CHEBI:16007 - kegg.compound: C00409 + - sbo: SBO:0000247 - !!omap - id: s_1151 - name: methylglyoxal @@ -8025,6 +8939,7 @@ - annotation: !!omap - chebi: CHEBI:17158 - kegg.compound: C00546 + - sbo: SBO:0000247 - !!omap - id: s_1153 - name: myo-inositol @@ -8034,6 +8949,7 @@ - annotation: !!omap - chebi: CHEBI:17268 - kegg.compound: C00137 + - sbo: SBO:0000247 - !!omap - id: s_1154 - name: myo-inositol @@ -8043,6 +8959,7 @@ - annotation: !!omap - chebi: CHEBI:17268 - kegg.compound: C00137 + - sbo: SBO:0000247 - !!omap - id: s_1156 - name: myo-inositol 1,3,4,5,6-pentakisphosphate @@ -8052,6 +8969,7 @@ - annotation: !!omap - chebi: CHEBI:57733 - kegg.compound: C01284 + - sbo: SBO:0000247 - !!omap - id: s_1157 - name: myo-inositol 1,3,4,5,6-pentakisphosphate @@ -8061,6 +8979,7 @@ - annotation: !!omap - chebi: CHEBI:57733 - kegg.compound: C01284 + - sbo: SBO:0000247 - !!omap - id: s_1158 - name: myo-inositol hexakisphosphate @@ -8070,6 +8989,7 @@ - annotation: !!omap - chebi: CHEBI:58130 - kegg.compound: C01204 + - sbo: SBO:0000247 - !!omap - id: s_1159 - name: myo-inositol hexakisphosphate @@ -8079,6 +8999,7 @@ - annotation: !!omap - chebi: CHEBI:58130 - kegg.compound: C01204 + - sbo: SBO:0000247 - !!omap - id: s_1161 - name: myristate @@ -8088,6 +9009,7 @@ - annotation: !!omap - chebi: CHEBI:30807 - kegg.compound: C06424 + - sbo: SBO:0000247 - !!omap - id: s_1163 - name: myristate @@ -8097,6 +9019,7 @@ - annotation: !!omap - chebi: CHEBI:30807 - kegg.compound: C06424 + - sbo: SBO:0000247 - !!omap - id: s_1166 - name: myristate @@ -8106,6 +9029,7 @@ - annotation: !!omap - chebi: CHEBI:30807 - kegg.compound: C06424 + - sbo: SBO:0000247 - !!omap - id: s_1176 - name: myristoyl-CoA @@ -8115,6 +9039,7 @@ - annotation: !!omap - chebi: CHEBI:57385 - kegg.compound: C02593 + - sbo: SBO:0000247 - !!omap - id: s_1179 - name: myristoyl-CoA @@ -8124,6 +9049,7 @@ - annotation: !!omap - chebi: CHEBI:57385 - kegg.compound: C02593 + - sbo: SBO:0000247 - !!omap - id: s_1180 - name: N(1)-acetylspermidine @@ -8133,6 +9059,7 @@ - annotation: !!omap - chebi: CHEBI:58324 - kegg.compound: C00612 + - sbo: SBO:0000247 - !!omap - id: s_1181 - name: N(1)-acetylspermine @@ -8142,6 +9069,7 @@ - annotation: !!omap - chebi: CHEBI:58101 - kegg.compound: C02567 + - sbo: SBO:0000247 - !!omap - id: s_1182 - name: N(2)-acetyl-L-ornithine @@ -8151,6 +9079,7 @@ - annotation: !!omap - chebi: CHEBI:16543 - kegg.compound: C00437 + - sbo: SBO:0000247 - !!omap - id: s_1183 - name: N(pros)-methyl-L-histidine @@ -8160,6 +9089,7 @@ - annotation: !!omap - chebi: CHEBI:27596 - kegg.compound: C01152 + - sbo: SBO:0000247 - !!omap - id: s_1184 - name: N,N'-diacetylchitobiosyldiphosphodolichol @@ -8169,6 +9099,7 @@ - annotation: !!omap - chebi: CHEBI:12427 - kegg.compound: C04537 + - sbo: SBO:0000247 - !!omap - id: s_1185 - name: N,N'-diformyldityrosine @@ -8177,6 +9108,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:50611 + - sbo: SBO:0000247 - !!omap - id: s_1186 - name: N,N'-diformyldityrosine @@ -8185,6 +9117,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:50611 + - sbo: SBO:0000247 - !!omap - id: s_1187 - name: N-(5-phospho-beta-D-ribosyl)anthranilate @@ -8194,6 +9127,7 @@ - annotation: !!omap - chebi: CHEBI:18277 - kegg.compound: C04302 + - sbo: SBO:0000247 - !!omap - id: s_1188 - name: N-[(R)-4-phosphonopantothenoyl]-L-cysteine @@ -8203,6 +9137,7 @@ - annotation: !!omap - chebi: CHEBI:59458 - kegg.compound: C04352 + - sbo: SBO:0000247 - !!omap - id: s_1189 - name: N-acetyl-alpha-D-glucosamine 1-phosphate @@ -8212,6 +9147,7 @@ - annotation: !!omap - chebi: CHEBI:16446 - kegg.compound: C04501 + - sbo: SBO:0000247 - !!omap - id: s_1190 - name: N-acetyl-D-glucosamine 6-phosphate @@ -8221,6 +9157,7 @@ - annotation: !!omap - chebi: CHEBI:57513 - kegg.compound: C00357 + - sbo: SBO:0000247 - !!omap - id: s_1191 - name: N-acetyl-L-gamma-glutamyl phosphate @@ -8230,6 +9167,7 @@ - annotation: !!omap - chebi: CHEBI:57936 - kegg.compound: C04133 + - sbo: SBO:0000247 - !!omap - id: s_1192 - name: N-acetyl-L-glutamate @@ -8239,6 +9177,7 @@ - annotation: !!omap - chebi: CHEBI:44337 - kegg.compound: C00624 + - sbo: SBO:0000247 - !!omap - id: s_1193 - name: N-acetylputrescine @@ -8248,6 +9187,7 @@ - annotation: !!omap - chebi: CHEBI:58263 - kegg.compound: C02714 + - sbo: SBO:0000247 - !!omap - id: s_1194 - name: N-carbamoyl-L-aspartate @@ -8257,6 +9197,7 @@ - annotation: !!omap - chebi: CHEBI:32814 - kegg.compound: C00438 + - sbo: SBO:0000247 - !!omap - id: s_1195 - name: N-formyl-L-kynurenine @@ -8266,6 +9207,7 @@ - annotation: !!omap - chebi: CHEBI:30249 - kegg.compound: C02700 + - sbo: SBO:0000247 - !!omap - id: s_1196 - name: N-formyl-L-tyrosine @@ -8274,6 +9216,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:50603 + - sbo: SBO:0000247 - !!omap - id: s_1198 - name: NAD @@ -8283,6 +9226,7 @@ - annotation: !!omap - chebi: CHEBI:57540 - kegg.compound: C00003 + - sbo: SBO:0000247 - !!omap - id: s_1199 - name: NAD @@ -8292,6 +9236,7 @@ - annotation: !!omap - chebi: CHEBI:57540 - kegg.compound: C00003 + - sbo: SBO:0000247 - !!omap - id: s_1200 - name: NAD @@ -8301,6 +9246,7 @@ - annotation: !!omap - chebi: CHEBI:57540 - kegg.compound: C00003 + - sbo: SBO:0000247 - !!omap - id: s_1201 - name: NAD @@ -8310,6 +9256,7 @@ - annotation: !!omap - chebi: CHEBI:57540 - kegg.compound: C00003 + - sbo: SBO:0000247 - !!omap - id: s_1202 - name: NAD @@ -8319,6 +9266,7 @@ - annotation: !!omap - chebi: CHEBI:57540 - kegg.compound: C00003 + - sbo: SBO:0000247 - !!omap - id: s_1203 - name: NADH @@ -8328,6 +9276,7 @@ - annotation: !!omap - chebi: CHEBI:57945 - kegg.compound: C00004 + - sbo: SBO:0000247 - !!omap - id: s_1204 - name: NADH @@ -8337,6 +9286,7 @@ - annotation: !!omap - chebi: CHEBI:57945 - kegg.compound: C00004 + - sbo: SBO:0000247 - !!omap - id: s_1205 - name: NADH @@ -8346,6 +9296,7 @@ - annotation: !!omap - chebi: CHEBI:57945 - kegg.compound: C00004 + - sbo: SBO:0000247 - !!omap - id: s_1206 - name: NADH @@ -8355,6 +9306,7 @@ - annotation: !!omap - chebi: CHEBI:57945 - kegg.compound: C00004 + - sbo: SBO:0000247 - !!omap - id: s_1207 - name: NADP(+) @@ -8364,6 +9316,7 @@ - annotation: !!omap - chebi: CHEBI:58349 - kegg.compound: C00006 + - sbo: SBO:0000247 - !!omap - id: s_1208 - name: NADP(+) @@ -8373,6 +9326,7 @@ - annotation: !!omap - chebi: CHEBI:58349 - kegg.compound: C00006 + - sbo: SBO:0000247 - !!omap - id: s_1210 - name: NADP(+) @@ -8382,6 +9336,7 @@ - annotation: !!omap - chebi: CHEBI:58349 - kegg.compound: C00006 + - sbo: SBO:0000247 - !!omap - id: s_1211 - name: NADP(+) @@ -8391,6 +9346,7 @@ - annotation: !!omap - chebi: CHEBI:58349 - kegg.compound: C00006 + - sbo: SBO:0000247 - !!omap - id: s_1212 - name: NADPH @@ -8400,6 +9356,7 @@ - annotation: !!omap - chebi: CHEBI:57783 - kegg.compound: C00005 + - sbo: SBO:0000247 - !!omap - id: s_1213 - name: NADPH @@ -8409,6 +9366,7 @@ - annotation: !!omap - chebi: CHEBI:57783 - kegg.compound: C00005 + - sbo: SBO:0000247 - !!omap - id: s_1214 - name: NADPH @@ -8418,6 +9376,7 @@ - annotation: !!omap - chebi: CHEBI:57783 - kegg.compound: C00005 + - sbo: SBO:0000247 - !!omap - id: s_1215 - name: NADPH @@ -8427,6 +9386,7 @@ - annotation: !!omap - chebi: CHEBI:57783 - kegg.compound: C00005 + - sbo: SBO:0000247 - !!omap - id: s_1216 - name: nicotinamide @@ -8436,6 +9396,7 @@ - annotation: !!omap - chebi: CHEBI:17154 - kegg.compound: C00153 + - sbo: SBO:0000247 - !!omap - id: s_1217 - name: nicotinamide @@ -8445,6 +9406,7 @@ - annotation: !!omap - chebi: CHEBI:17154 - kegg.compound: C00153 + - sbo: SBO:0000247 - !!omap - id: s_1218 - name: nicotinamide ribose @@ -8454,6 +9416,7 @@ - annotation: !!omap - chebi: CHEBI:15927 - kegg.compound: C03150 + - sbo: SBO:0000247 - !!omap - id: s_1219 - name: nicotinate @@ -8463,6 +9426,7 @@ - annotation: !!omap - chebi: CHEBI:32544 - kegg.compound: C00253 + - sbo: SBO:0000247 - !!omap - id: s_1220 - name: nicotinate @@ -8472,6 +9436,7 @@ - annotation: !!omap - chebi: CHEBI:32544 - kegg.compound: C00253 + - sbo: SBO:0000247 - !!omap - id: s_1221 - name: nicotinate @@ -8481,6 +9446,7 @@ - annotation: !!omap - chebi: CHEBI:32544 - kegg.compound: C00253 + - sbo: SBO:0000247 - !!omap - id: s_1222 - name: nicotinic acid D-ribonucleotide @@ -8490,6 +9456,7 @@ - annotation: !!omap - chebi: CHEBI:57502 - kegg.compound: C01185 + - sbo: SBO:0000247 - !!omap - id: s_1223 - name: nicotinic acid D-ribonucleotide @@ -8499,6 +9466,7 @@ - annotation: !!omap - chebi: CHEBI:57502 - kegg.compound: C01185 + - sbo: SBO:0000247 - !!omap - id: s_1224 - name: NMN @@ -8508,6 +9476,7 @@ - annotation: !!omap - chebi: CHEBI:14649 - kegg.compound: C00455 + - sbo: SBO:0000247 - !!omap - id: s_1225 - name: NMN @@ -8517,6 +9486,7 @@ - annotation: !!omap - chebi: CHEBI:14649 - kegg.compound: C00455 + - sbo: SBO:0000247 - !!omap - id: s_1227 - name: NMN @@ -8526,6 +9496,7 @@ - annotation: !!omap - chebi: CHEBI:14649 - kegg.compound: C00455 + - sbo: SBO:0000247 - !!omap - id: s_1228 - name: NMN @@ -8535,6 +9506,7 @@ - annotation: !!omap - chebi: CHEBI:14649 - kegg.compound: C00455 + - sbo: SBO:0000247 - !!omap - id: s_1229 - name: nonadecaprenyl diphosphate @@ -8543,6 +9515,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53034 + - sbo: SBO:0000247 - !!omap - id: s_1230 - name: nonaprenyl 4-hydroxybenzoate @@ -8552,6 +9525,7 @@ - annotation: !!omap - chebi: CHEBI:18162 - kegg.compound: C03885 + - sbo: SBO:0000247 - !!omap - id: s_1231 - name: nonaprenyl diphosphate @@ -8561,6 +9535,7 @@ - annotation: !!omap - chebi: CHEBI:53044 - kegg.compound: C04145 + - sbo: SBO:0000247 - !!omap - id: s_1232 - name: nonaprenyl diphosphate @@ -8570,6 +9545,7 @@ - annotation: !!omap - chebi: CHEBI:53044 - kegg.compound: C04145 + - sbo: SBO:0000247 - !!omap - id: s_1233 - name: O-acetyl-L-homoserine @@ -8579,6 +9555,7 @@ - annotation: !!omap - chebi: CHEBI:16288 - kegg.compound: C01077 + - sbo: SBO:0000247 - !!omap - id: s_1234 - name: O-acetyl-L-serine @@ -8588,6 +9565,7 @@ - annotation: !!omap - chebi: CHEBI:17981 - kegg.compound: C00979 + - sbo: SBO:0000247 - !!omap - id: s_1235 - name: O-acetylcarnitine @@ -8597,6 +9575,7 @@ - annotation: !!omap - chebi: CHEBI:57589 - kegg.compound: C02571 + - sbo: SBO:0000247 - !!omap - id: s_1236 - name: O-acetylcarnitine @@ -8606,6 +9585,7 @@ - annotation: !!omap - chebi: CHEBI:57589 - kegg.compound: C02571 + - sbo: SBO:0000247 - !!omap - id: s_1237 - name: O-acetylcarnitine @@ -8615,6 +9595,7 @@ - annotation: !!omap - chebi: CHEBI:57589 - kegg.compound: C02571 + - sbo: SBO:0000247 - !!omap - id: s_1238 - name: O-phospho-L-homoserine @@ -8624,6 +9605,7 @@ - annotation: !!omap - chebi: CHEBI:57590 - kegg.compound: C01102 + - sbo: SBO:0000247 - !!omap - id: s_1239 - name: O-phosphoethanolamine @@ -8633,6 +9615,7 @@ - annotation: !!omap - chebi: CHEBI:58190 - kegg.compound: C00346 + - sbo: SBO:0000247 - !!omap - id: s_1240 - name: O-phosphoethanolamine @@ -8642,6 +9625,7 @@ - annotation: !!omap - chebi: CHEBI:58190 - kegg.compound: C00346 + - sbo: SBO:0000247 - !!omap - id: s_1241 - name: O-succinyl-L-homoserine @@ -8651,6 +9635,7 @@ - annotation: !!omap - chebi: CHEBI:57661 - kegg.compound: C01118 + - sbo: SBO:0000247 - !!omap - id: s_1246 - name: octadecaprenyl diphosphate @@ -8659,6 +9644,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53035 + - sbo: SBO:0000247 - !!omap - id: s_1248 - name: octanoate @@ -8668,6 +9654,7 @@ - annotation: !!omap - chebi: CHEBI:25646 - kegg.compound: C06423 + - sbo: SBO:0000247 - !!omap - id: s_1250 - name: octanoate @@ -8677,6 +9664,7 @@ - annotation: !!omap - chebi: CHEBI:25646 - kegg.compound: C06423 + - sbo: SBO:0000247 - !!omap - id: s_1253 - name: octanoate @@ -8686,6 +9674,7 @@ - annotation: !!omap - chebi: CHEBI:25646 - kegg.compound: C06423 + - sbo: SBO:0000247 - !!omap - id: s_1254 - name: octanoyl-ACP @@ -8695,6 +9684,7 @@ - annotation: !!omap - chebi: CHEBI:7725 - kegg.compound: C05752 + - sbo: SBO:0000247 - !!omap - id: s_1258 - name: octanoyl-CoA @@ -8704,6 +9694,7 @@ - annotation: !!omap - chebi: CHEBI:57386 - kegg.compound: C01944 + - sbo: SBO:0000247 - !!omap - id: s_1259 - name: octaprenyl diphosphate @@ -8713,6 +9704,7 @@ - annotation: !!omap - chebi: CHEBI:53045 - kegg.compound: C04146 + - sbo: SBO:0000247 - !!omap - id: s_1260 - name: oleate @@ -8722,6 +9714,7 @@ - annotation: !!omap - chebi: CHEBI:30823 - kegg.compound: C00712 + - sbo: SBO:0000247 - !!omap - id: s_1262 - name: oleoyl-CoA @@ -8731,6 +9724,7 @@ - annotation: !!omap - chebi: CHEBI:57387 - kegg.compound: C00510 + - sbo: SBO:0000247 - !!omap - id: s_1265 - name: oleoyl-CoA @@ -8740,6 +9734,7 @@ - annotation: !!omap - chebi: CHEBI:57387 - kegg.compound: C00510 + - sbo: SBO:0000247 - !!omap - id: s_1266 - name: ornithine @@ -8749,6 +9744,7 @@ - annotation: !!omap - chebi: CHEBI:46912 - kegg.compound: C01602 + - sbo: SBO:0000247 - !!omap - id: s_1267 - name: ornithine @@ -8758,6 +9754,7 @@ - annotation: !!omap - chebi: CHEBI:46912 - kegg.compound: C01602 + - sbo: SBO:0000247 - !!omap - id: s_1268 - name: ornithine @@ -8767,6 +9764,7 @@ - annotation: !!omap - chebi: CHEBI:46912 - kegg.compound: C01602 + - sbo: SBO:0000247 - !!omap - id: s_1269 - name: orotate @@ -8776,6 +9774,7 @@ - annotation: !!omap - chebi: CHEBI:30839 - kegg.compound: C00295 + - sbo: SBO:0000247 - !!omap - id: s_1270 - name: orotidine 5'-(dihydrogen phosphate) @@ -8785,6 +9784,7 @@ - annotation: !!omap - chebi: CHEBI:57538 - kegg.compound: C01103 + - sbo: SBO:0000247 - !!omap - id: s_1271 - name: oxaloacetate @@ -8794,6 +9794,7 @@ - annotation: !!omap - chebi: CHEBI:16452 - kegg.compound: C00036 + - sbo: SBO:0000247 - !!omap - id: s_1272 - name: oxaloacetate @@ -8803,6 +9804,7 @@ - annotation: !!omap - chebi: CHEBI:16452 - kegg.compound: C00036 + - sbo: SBO:0000247 - !!omap - id: s_1273 - name: oxaloacetate @@ -8812,6 +9814,7 @@ - annotation: !!omap - chebi: CHEBI:16452 - kegg.compound: C00036 + - sbo: SBO:0000247 - !!omap - id: s_1274 - name: oxaloacetate @@ -8821,6 +9824,7 @@ - annotation: !!omap - chebi: CHEBI:16452 - kegg.compound: C00036 + - sbo: SBO:0000247 - !!omap - id: s_1275 - name: oxygen @@ -8830,6 +9834,7 @@ - annotation: !!omap - chebi: CHEBI:15379 - kegg.compound: C00007 + - sbo: SBO:0000247 - !!omap - id: s_1276 - name: oxygen @@ -8839,6 +9844,7 @@ - annotation: !!omap - chebi: CHEBI:15379 - kegg.compound: C00007 + - sbo: SBO:0000247 - !!omap - id: s_1277 - name: oxygen @@ -8848,6 +9854,7 @@ - annotation: !!omap - chebi: CHEBI:15379 - kegg.compound: C00007 + - sbo: SBO:0000247 - !!omap - id: s_1278 - name: oxygen @@ -8857,6 +9864,7 @@ - annotation: !!omap - chebi: CHEBI:15379 - kegg.compound: C00007 + - sbo: SBO:0000247 - !!omap - id: s_1279 - name: oxygen @@ -8866,6 +9874,7 @@ - annotation: !!omap - chebi: CHEBI:15379 - kegg.compound: C00007 + - sbo: SBO:0000247 - !!omap - id: s_1282 - name: P(1),P(4)-bis(5'-adenosyl) tetraphosphate @@ -8875,6 +9884,7 @@ - annotation: !!omap - chebi: CHEBI:58141 - kegg.compound: C01260 + - sbo: SBO:0000247 - !!omap - id: s_1283 - name: P(1),P(4)-bis(5'-guanosyl) tetraphosphate @@ -8884,6 +9894,7 @@ - annotation: !!omap - chebi: CHEBI:57553 - kegg.compound: C01261 + - sbo: SBO:0000247 - !!omap - id: s_1284 - name: P1-(5'-adenosyl),P4-(5'-guanosyl) tetraphosphate @@ -8892,6 +9903,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52968 + - sbo: SBO:0000247 - !!omap - id: s_1286 - name: palmitate @@ -8901,6 +9913,7 @@ - annotation: !!omap - chebi: CHEBI:7896 - kegg.compound: C00249 + - sbo: SBO:0000247 - !!omap - id: s_1288 - name: palmitate @@ -8910,6 +9923,7 @@ - annotation: !!omap - chebi: CHEBI:7896 - kegg.compound: C00249 + - sbo: SBO:0000247 - !!omap - id: s_1291 - name: palmitate @@ -8919,6 +9933,7 @@ - annotation: !!omap - chebi: CHEBI:7896 - kegg.compound: C00249 + - sbo: SBO:0000247 - !!omap - id: s_1293 - name: palmitoleate @@ -8928,6 +9943,7 @@ - annotation: !!omap - chebi: CHEBI:32372 - kegg.compound: C08362 + - sbo: SBO:0000247 - !!omap - id: s_1295 - name: palmitoleate @@ -8937,6 +9953,7 @@ - annotation: !!omap - chebi: CHEBI:32372 - kegg.compound: C08362 + - sbo: SBO:0000247 - !!omap - id: s_1298 - name: palmitoleate @@ -8946,6 +9963,7 @@ - annotation: !!omap - chebi: CHEBI:32372 - kegg.compound: C08362 + - sbo: SBO:0000247 - !!omap - id: s_1302 - name: palmitoyl-CoA @@ -8955,6 +9973,7 @@ - annotation: !!omap - chebi: CHEBI:57379 - kegg.compound: C00154 + - sbo: SBO:0000247 - !!omap - id: s_1303 - name: palmitoyl-CoA @@ -8964,6 +9983,7 @@ - annotation: !!omap - chebi: CHEBI:57379 - kegg.compound: C00154 + - sbo: SBO:0000247 - !!omap - id: s_1305 - name: palmitoyl-CoA @@ -8973,6 +9993,7 @@ - annotation: !!omap - chebi: CHEBI:57379 - kegg.compound: C00154 + - sbo: SBO:0000247 - !!omap - id: s_1307 - name: pantetheine 4'-phosphate @@ -8982,6 +10003,7 @@ - annotation: !!omap - chebi: CHEBI:47942 - kegg.compound: C01134 + - sbo: SBO:0000247 - !!omap - id: s_1308 - name: pantetheine 4'-phosphate @@ -8991,6 +10013,7 @@ - annotation: !!omap - chebi: CHEBI:47942 - kegg.compound: C01134 + - sbo: SBO:0000247 - !!omap - id: s_1309 - name: pectin @@ -9000,6 +10023,7 @@ - annotation: !!omap - chebi: CHEBI:17309 - kegg.compound: C00714 + - sbo: SBO:0000247 - !!omap - id: s_1310 - name: pentadecaprenyl diphosphate @@ -9008,6 +10032,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53038 + - sbo: SBO:0000247 - !!omap - id: s_1311 - name: pentaprenyl diphosphate @@ -9017,6 +10042,7 @@ - annotation: !!omap - chebi: CHEBI:53048 - kegg.compound: C04217 + - sbo: SBO:0000247 - !!omap - id: s_1312 - name: pentaprenyl diphosphate @@ -9026,6 +10052,7 @@ - annotation: !!omap - chebi: CHEBI:53048 - kegg.compound: C04217 + - sbo: SBO:0000247 - !!omap - id: s_1313 - name: pentaprenyl diphosphate @@ -9035,6 +10062,7 @@ - annotation: !!omap - chebi: CHEBI:53048 - kegg.compound: C04217 + - sbo: SBO:0000247 - !!omap - id: s_1314 - name: Phe-tRNA(Phe) @@ -9044,6 +10072,7 @@ - annotation: !!omap - chebi: CHEBI:29153 - kegg.compound: C03511 + - sbo: SBO:0000247 - !!omap - id: s_1315 - name: Phe-tRNA(Phe) @@ -9053,6 +10082,7 @@ - annotation: !!omap - chebi: CHEBI:29153 - kegg.compound: C03511 + - sbo: SBO:0000247 - !!omap - id: s_1316 - name: phenethyl acetate @@ -9062,6 +10092,7 @@ - annotation: !!omap - chebi: CHEBI:31988 - kegg.compound: C12303 + - sbo: SBO:0000247 - !!omap - id: s_1317 - name: phenethyl acetate @@ -9071,6 +10102,7 @@ - annotation: !!omap - chebi: CHEBI:31988 - kegg.compound: C12303 + - sbo: SBO:0000247 - !!omap - id: s_1318 - name: phenylacetaldehyde @@ -9080,6 +10112,7 @@ - annotation: !!omap - chebi: CHEBI:16424 - kegg.compound: C00601 + - sbo: SBO:0000247 - !!omap - id: s_1319 - name: phenylacetaldehyde @@ -9089,6 +10122,7 @@ - annotation: !!omap - chebi: CHEBI:16424 - kegg.compound: C00601 + - sbo: SBO:0000247 - !!omap - id: s_1320 - name: phenylacetaldehyde @@ -9098,6 +10132,7 @@ - annotation: !!omap - chebi: CHEBI:16424 - kegg.compound: C00601 + - sbo: SBO:0000247 - !!omap - id: s_1321 - name: phenylacetic acid @@ -9107,6 +10142,7 @@ - annotation: !!omap - chebi: CHEBI:18401 - kegg.compound: C07086 + - sbo: SBO:0000247 - !!omap - id: s_1322 - name: phosphate @@ -9116,6 +10152,7 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_1323 - name: phosphate @@ -9125,6 +10162,7 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_1324 - name: phosphate @@ -9134,6 +10172,7 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_1325 - name: phosphate @@ -9143,6 +10182,7 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_1326 - name: phosphate @@ -9152,6 +10192,7 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_1329 - name: phosphate @@ -9161,6 +10202,7 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_1337 - name: phosphatidyl-L-serine backbone @@ -9170,6 +10212,7 @@ - annotation: !!omap - chebi: CHEBI:18303 - kegg.compound: C02737 + - sbo: SBO:0000649 - !!omap - id: s_1346 - name: phosphatidylcholine backbone @@ -9179,6 +10222,7 @@ - annotation: !!omap - chebi: CHEBI:49183 - kegg.compound: C00157 + - sbo: SBO:0000649 - !!omap - id: s_1351 - name: phosphatidylethanolamine backbone @@ -9188,6 +10232,7 @@ - annotation: !!omap - chebi: CHEBI:16038 - kegg.compound: C00350 + - sbo: SBO:0000649 - !!omap - id: s_1352 - name: phosphatidylethanolamine backbone @@ -9197,6 +10242,7 @@ - annotation: !!omap - chebi: CHEBI:16038 - kegg.compound: C00350 + - sbo: SBO:0000649 - !!omap - id: s_1360 - name: phosphoenolpyruvate @@ -9206,6 +10252,7 @@ - annotation: !!omap - chebi: CHEBI:58702 - kegg.compound: C00074 + - sbo: SBO:0000247 - !!omap - id: s_1361 - name: phosphoenolpyruvate @@ -9215,6 +10262,7 @@ - annotation: !!omap - chebi: CHEBI:58702 - kegg.compound: C00074 + - sbo: SBO:0000247 - !!omap - id: s_1364 - name: phosphoribosyl-carboxy-aminoimidazole @@ -9224,6 +10272,7 @@ - annotation: !!omap - chebi: CHEBI:58564 - kegg.compound: C04751 + - sbo: SBO:0000247 - !!omap - id: s_1365 - name: phosphoribosyl-formamido-carboxamide @@ -9233,6 +10282,7 @@ - annotation: !!omap - chebi: CHEBI:58467 - kegg.compound: C04734 + - sbo: SBO:0000247 - !!omap - id: s_1366 - name: phytosphingosine @@ -9242,6 +10292,7 @@ - annotation: !!omap - chebi: CHEBI:46961 - kegg.compound: C12144 + - sbo: SBO:0000247 - !!omap - id: s_1367 - name: phytosphingosine 1-phosphate @@ -9250,6 +10301,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:46970 + - sbo: SBO:0000247 - !!omap - id: s_1368 - name: pimeloyl-CoA @@ -9259,6 +10311,7 @@ - annotation: !!omap - chebi: CHEBI:57360 - kegg.compound: C01063 + - sbo: SBO:0000247 - !!omap - id: s_1371 - name: polysulphur @@ -9268,6 +10321,7 @@ - annotation: !!omap - chebi: CHEBI:17909 - kegg.compound: C00087 + - sbo: SBO:0000247 - !!omap - id: s_1372 - name: porphobilinogen @@ -9277,6 +10331,7 @@ - annotation: !!omap - chebi: CHEBI:58126 - kegg.compound: C00931 + - sbo: SBO:0000247 - !!omap - id: s_1373 - name: potassium @@ -9286,6 +10341,7 @@ - annotation: !!omap - chebi: CHEBI:26216 - kegg.compound: C00238 + - sbo: SBO:0000247 - !!omap - id: s_1374 - name: potassium @@ -9295,6 +10351,7 @@ - annotation: !!omap - chebi: CHEBI:26216 - kegg.compound: C00238 + - sbo: SBO:0000247 - !!omap - id: s_1375 - name: precorrin-2 @@ -9304,6 +10361,7 @@ - annotation: !!omap - chebi: CHEBI:58827 - kegg.compound: C02463 + - sbo: SBO:0000247 - !!omap - id: s_1376 - name: prenyl diphosphate(3-) @@ -9313,6 +10371,7 @@ - annotation: !!omap - chebi: CHEBI:57623 - kegg.compound: C00235 + - sbo: SBO:0000247 - !!omap - id: s_1377 - name: prephenate @@ -9322,6 +10381,7 @@ - annotation: !!omap - chebi: CHEBI:29934 - kegg.compound: C00254 + - sbo: SBO:0000247 - !!omap - id: s_1378 - name: preuroporphyrinogen @@ -9331,6 +10391,7 @@ - annotation: !!omap - chebi: CHEBI:57845 - kegg.compound: C01024 + - sbo: SBO:0000247 - !!omap - id: s_1379 - name: Pro-tRNA(Pro) @@ -9340,6 +10401,7 @@ - annotation: !!omap - chebi: CHEBI:29154 - kegg.compound: C02702 + - sbo: SBO:0000247 - !!omap - id: s_1382 - name: propionyl-CoA @@ -9349,6 +10411,7 @@ - annotation: !!omap - chebi: CHEBI:57392 - kegg.compound: C00100 + - sbo: SBO:0000247 - !!omap - id: s_1383 - name: protoporphyrin @@ -9358,6 +10421,7 @@ - annotation: !!omap - chebi: CHEBI:36159 - kegg.compound: C02191 + - sbo: SBO:0000247 - !!omap - id: s_1384 - name: protoporphyrinogen @@ -9367,6 +10431,7 @@ - annotation: !!omap - chebi: CHEBI:57307 - kegg.compound: C01079 + - sbo: SBO:0000247 - !!omap - id: s_1385 - name: protoporphyrinogen @@ -9376,6 +10441,7 @@ - annotation: !!omap - chebi: CHEBI:57307 - kegg.compound: C01079 + - sbo: SBO:0000247 - !!omap - id: s_1386 - name: PRPP @@ -9385,6 +10451,7 @@ - annotation: !!omap - chebi: CHEBI:58017 - kegg.compound: C00119 + - sbo: SBO:0000247 - !!omap - id: s_1387 - name: PRPP @@ -9394,6 +10461,7 @@ - annotation: !!omap - chebi: CHEBI:58017 - kegg.compound: C00119 + - sbo: SBO:0000247 - !!omap - id: s_1388 - name: pseudouridine 5'-phosphate @@ -9403,6 +10471,7 @@ - annotation: !!omap - chebi: CHEBI:58380 - kegg.compound: C01168 + - sbo: SBO:0000247 - !!omap - id: s_1389 - name: putrescine @@ -9412,6 +10481,7 @@ - annotation: !!omap - chebi: CHEBI:326268 - kegg.compound: C00134 + - sbo: SBO:0000247 - !!omap - id: s_1390 - name: putrescine @@ -9421,6 +10491,7 @@ - annotation: !!omap - chebi: CHEBI:326268 - kegg.compound: C00134 + - sbo: SBO:0000247 - !!omap - id: s_1391 - name: putrescine @@ -9430,6 +10501,7 @@ - annotation: !!omap - chebi: CHEBI:326268 - kegg.compound: C00134 + - sbo: SBO:0000247 - !!omap - id: s_1392 - name: pyridoxal @@ -9439,6 +10511,7 @@ - annotation: !!omap - chebi: CHEBI:17310 - kegg.compound: C00250 + - sbo: SBO:0000247 - !!omap - id: s_1393 - name: pyridoxal 5'-phosphate @@ -9448,6 +10521,7 @@ - annotation: !!omap - chebi: CHEBI:597326 - kegg.compound: C00018 + - sbo: SBO:0000247 - !!omap - id: s_1394 - name: pyridoxamine @@ -9457,6 +10531,7 @@ - annotation: !!omap - chebi: CHEBI:57761 - kegg.compound: C00534 + - sbo: SBO:0000247 - !!omap - id: s_1395 - name: pyridoxamine 5'-phosphate @@ -9466,6 +10541,7 @@ - annotation: !!omap - chebi: CHEBI:58451 - kegg.compound: C00647 + - sbo: SBO:0000247 - !!omap - id: s_1396 - name: pyridoxine @@ -9475,6 +10551,7 @@ - annotation: !!omap - chebi: CHEBI:16709 - kegg.compound: C00314 + - sbo: SBO:0000247 - !!omap - id: s_1397 - name: pyridoxine @@ -9484,6 +10561,7 @@ - annotation: !!omap - chebi: CHEBI:16709 - kegg.compound: C00314 + - sbo: SBO:0000247 - !!omap - id: s_1398 - name: pyridoxine 5'-phosphate @@ -9493,6 +10571,7 @@ - annotation: !!omap - chebi: CHEBI:58589 - kegg.compound: C00627 + - sbo: SBO:0000247 - !!omap - id: s_1399 - name: pyruvate @@ -9502,6 +10581,7 @@ - annotation: !!omap - chebi: CHEBI:15361 - kegg.compound: C00022 + - sbo: SBO:0000247 - !!omap - id: s_1400 - name: pyruvate @@ -9511,6 +10591,7 @@ - annotation: !!omap - chebi: CHEBI:15361 - kegg.compound: C00022 + - sbo: SBO:0000247 - !!omap - id: s_1401 - name: pyruvate @@ -9520,6 +10601,7 @@ - annotation: !!omap - chebi: CHEBI:15361 - kegg.compound: C00022 + - sbo: SBO:0000247 - !!omap - id: s_1403 - name: quinolinate @@ -9529,6 +10611,7 @@ - annotation: !!omap - chebi: CHEBI:29959 - kegg.compound: C03722 + - sbo: SBO:0000247 - !!omap - id: s_1404 - name: quinolinate @@ -9538,6 +10621,7 @@ - annotation: !!omap - chebi: CHEBI:29959 - kegg.compound: C03722 + - sbo: SBO:0000247 - !!omap - id: s_1405 - name: riboflavin @@ -9547,6 +10631,7 @@ - annotation: !!omap - chebi: CHEBI:57986 - kegg.compound: C00255 + - sbo: SBO:0000247 - !!omap - id: s_1406 - name: riboflavin @@ -9556,6 +10641,7 @@ - annotation: !!omap - chebi: CHEBI:57986 - kegg.compound: C00255 + - sbo: SBO:0000247 - !!omap - id: s_1407 - name: riboflavin @@ -9565,6 +10651,7 @@ - annotation: !!omap - chebi: CHEBI:57986 - kegg.compound: C00255 + - sbo: SBO:0000247 - !!omap - id: s_1408 - name: ribose-5-phosphate @@ -9574,6 +10661,7 @@ - annotation: !!omap - chebi: CHEBI:18189 - kegg.compound: C03736 + - sbo: SBO:0000247 - !!omap - id: s_1409 - name: S(8)-aminomethyldihydrolipoamide @@ -9582,6 +10670,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:50622 + - sbo: SBO:0000247 - !!omap - id: s_1410 - name: S(8)-aminomethyldihydrolipoylprotein @@ -9591,6 +10680,7 @@ - annotation: !!omap - chebi: CHEBI:16882 - kegg.compound: C01242 + - sbo: SBO:0000247 - !!omap - id: s_1411 - name: S(8)-succinyldihydrolipoamide @@ -9600,6 +10690,7 @@ - annotation: !!omap - chebi: CHEBI:17432 - kegg.compound: C01169 + - sbo: SBO:0000247 - !!omap - id: s_1412 - name: S-adenosyl-4-methylthio-2-oxobutanoate @@ -9609,6 +10700,7 @@ - annotation: !!omap - chebi: CHEBI:16490 - kegg.compound: C04425 + - sbo: SBO:0000247 - !!omap - id: s_1413 - name: S-adenosyl-L-homocysteine @@ -9618,6 +10710,7 @@ - annotation: !!omap - chebi: CHEBI:16680 - kegg.compound: C00021 + - sbo: SBO:0000247 - !!omap - id: s_1415 - name: S-adenosyl-L-homocysteine @@ -9627,6 +10720,7 @@ - annotation: !!omap - chebi: CHEBI:16680 - kegg.compound: C00021 + - sbo: SBO:0000247 - !!omap - id: s_1416 - name: S-adenosyl-L-methionine @@ -9636,6 +10730,7 @@ - annotation: !!omap - chebi: CHEBI:15414 - kegg.compound: C00019 + - sbo: SBO:0000247 - !!omap - id: s_1418 - name: S-adenosyl-L-methionine @@ -9645,6 +10740,7 @@ - annotation: !!omap - chebi: CHEBI:15414 - kegg.compound: C00019 + - sbo: SBO:0000247 - !!omap - id: s_1419 - name: S-adenosyl-L-methionine @@ -9654,6 +10750,7 @@ - annotation: !!omap - chebi: CHEBI:15414 - kegg.compound: C00019 + - sbo: SBO:0000247 - !!omap - id: s_1420 - name: S-adenosylmethioninamine @@ -9663,6 +10760,7 @@ - annotation: !!omap - chebi: CHEBI:57443 - kegg.compound: C01137 + - sbo: SBO:0000247 - !!omap - id: s_1421 - name: S-formylglutathione @@ -9672,6 +10770,7 @@ - annotation: !!omap - chebi: CHEBI:57688 - kegg.compound: C01031 + - sbo: SBO:0000247 - !!omap - id: s_1422 - name: S-methyl-5-thio-alpha-D-ribose 1-phosphate @@ -9681,6 +10780,7 @@ - annotation: !!omap - chebi: CHEBI:58533 - kegg.compound: C04188 + - sbo: SBO:0000247 - !!omap - id: s_1423 - name: S-methyl-5-thio-D-ribulose 1-phosphate @@ -9690,6 +10790,7 @@ - annotation: !!omap - chebi: CHEBI:58548 - kegg.compound: C04582 + - sbo: SBO:0000247 - !!omap - id: s_1424 - name: S-methyl-L-methionine @@ -9699,6 +10800,7 @@ - annotation: !!omap - chebi: CHEBI:17728 - kegg.compound: C03172 + - sbo: SBO:0000247 - !!omap - id: s_1425 - name: S-methyl-L-methionine @@ -9708,6 +10810,7 @@ - annotation: !!omap - chebi: CHEBI:17728 - kegg.compound: C03172 + - sbo: SBO:0000247 - !!omap - id: s_1426 - name: sedoheptulose 1,7-bisphosphate @@ -9717,6 +10820,7 @@ - annotation: !!omap - chebi: CHEBI:58335 - kegg.compound: C00447 + - sbo: SBO:0000247 - !!omap - id: s_1427 - name: sedoheptulose 7-phosphate @@ -9726,6 +10830,7 @@ - annotation: !!omap - chebi: CHEBI:57483 - kegg.compound: C05382 + - sbo: SBO:0000247 - !!omap - id: s_1428 - name: Ser-tRNA(Ser) @@ -9735,6 +10840,7 @@ - annotation: !!omap - chebi: CHEBI:29162 - kegg.compound: C02553 + - sbo: SBO:0000247 - !!omap - id: s_1429 - name: shikimate @@ -9744,6 +10850,7 @@ - annotation: !!omap - chebi: CHEBI:36208 - kegg.compound: C00493 + - sbo: SBO:0000247 - !!omap - id: s_1430 - name: siroheme @@ -9753,6 +10860,7 @@ - annotation: !!omap - chebi: CHEBI:60052 - kegg.compound: C00748 + - sbo: SBO:0000247 - !!omap - id: s_1431 - name: sirohydrochlorin @@ -9762,6 +10870,7 @@ - annotation: !!omap - chebi: CHEBI:58351 - kegg.compound: C05778 + - sbo: SBO:0000247 - !!omap - id: s_1432 - name: sn-glycero-3-phosphocholine @@ -9771,6 +10880,7 @@ - annotation: !!omap - chebi: CHEBI:16870 - kegg.compound: C00670 + - sbo: SBO:0000247 - !!omap - id: s_1433 - name: sn-glycero-3-phosphocholine @@ -9780,6 +10890,7 @@ - annotation: !!omap - chebi: CHEBI:16870 - kegg.compound: C00670 + - sbo: SBO:0000247 - !!omap - id: s_1435 - name: sn-glycero-3-phosphocholine @@ -9789,6 +10900,7 @@ - annotation: !!omap - chebi: CHEBI:16870 - kegg.compound: C00670 + - sbo: SBO:0000247 - !!omap - id: s_1437 - name: sodium @@ -9798,6 +10910,7 @@ - annotation: !!omap - chebi: CHEBI:26708 - kegg.compound: C01330 + - sbo: SBO:0000247 - !!omap - id: s_1438 - name: sodium @@ -9807,6 +10920,7 @@ - annotation: !!omap - chebi: CHEBI:26708 - kegg.compound: C01330 + - sbo: SBO:0000247 - !!omap - id: s_1439 - name: spermidine @@ -9816,6 +10930,7 @@ - annotation: !!omap - chebi: CHEBI:57834 - kegg.compound: C00315 + - sbo: SBO:0000247 - !!omap - id: s_1440 - name: spermidine @@ -9825,6 +10940,7 @@ - annotation: !!omap - chebi: CHEBI:57834 - kegg.compound: C00315 + - sbo: SBO:0000247 - !!omap - id: s_1441 - name: spermidine @@ -9834,6 +10950,7 @@ - annotation: !!omap - chebi: CHEBI:57834 - kegg.compound: C00315 + - sbo: SBO:0000247 - !!omap - id: s_1442 - name: spermine @@ -9843,6 +10960,7 @@ - annotation: !!omap - chebi: CHEBI:45725 - kegg.compound: C00750 + - sbo: SBO:0000247 - !!omap - id: s_1443 - name: spermine @@ -9852,6 +10970,7 @@ - annotation: !!omap - chebi: CHEBI:45725 - kegg.compound: C00750 + - sbo: SBO:0000247 - !!omap - id: s_1444 - name: spermine @@ -9861,6 +10980,7 @@ - annotation: !!omap - chebi: CHEBI:45725 - kegg.compound: C00750 + - sbo: SBO:0000247 - !!omap - id: s_1445 - name: sphinganine @@ -9870,6 +10990,7 @@ - annotation: !!omap - chebi: CHEBI:57817 - kegg.compound: C00836 + - sbo: SBO:0000247 - !!omap - id: s_1446 - name: sphinganine 1-phosphate @@ -9879,6 +11000,7 @@ - annotation: !!omap - chebi: CHEBI:57939 - kegg.compound: C01120 + - sbo: SBO:0000247 - !!omap - id: s_1447 - name: squalene @@ -9888,6 +11010,7 @@ - annotation: !!omap - chebi: CHEBI:15440 - kegg.compound: C00751 + - sbo: SBO:0000247 - !!omap - id: s_1448 - name: squalene @@ -9897,6 +11020,7 @@ - annotation: !!omap - chebi: CHEBI:15440 - kegg.compound: C00751 + - sbo: SBO:0000247 - !!omap - id: s_1449 - name: stearate @@ -9906,6 +11030,7 @@ - annotation: !!omap - chebi: CHEBI:25629 - kegg.compound: C01530 + - sbo: SBO:0000247 - !!omap - id: s_1450 - name: stearate @@ -9915,6 +11040,7 @@ - annotation: !!omap - chebi: CHEBI:25629 - kegg.compound: C01530 + - sbo: SBO:0000247 - !!omap - id: s_1451 - name: stearate @@ -9924,6 +11050,7 @@ - annotation: !!omap - chebi: CHEBI:25629 - kegg.compound: C01530 + - sbo: SBO:0000247 - !!omap - id: s_1454 - name: stearoyl-CoA @@ -9933,6 +11060,7 @@ - annotation: !!omap - chebi: CHEBI:57394 - kegg.compound: C00412 + - sbo: SBO:0000247 - !!omap - id: s_1457 - name: stearoyl-CoA @@ -9942,6 +11070,7 @@ - annotation: !!omap - chebi: CHEBI:57394 - kegg.compound: C00412 + - sbo: SBO:0000247 - !!omap - id: s_1458 - name: succinate @@ -9951,6 +11080,7 @@ - annotation: !!omap - chebi: CHEBI:30031 - kegg.compound: C00042 + - sbo: SBO:0000247 - !!omap - id: s_1459 - name: succinate @@ -9960,6 +11090,7 @@ - annotation: !!omap - chebi: CHEBI:30031 - kegg.compound: C00042 + - sbo: SBO:0000247 - !!omap - id: s_1460 - name: succinate @@ -9969,6 +11100,7 @@ - annotation: !!omap - chebi: CHEBI:30031 - kegg.compound: C00042 + - sbo: SBO:0000247 - !!omap - id: s_1461 - name: succinic semialdehyde @@ -9978,6 +11110,7 @@ - annotation: !!omap - chebi: CHEBI:57706 - kegg.compound: C00232 + - sbo: SBO:0000247 - !!omap - id: s_1464 - name: succinyl-CoA @@ -9987,6 +11120,7 @@ - annotation: !!omap - chebi: CHEBI:57292 - kegg.compound: C00091 + - sbo: SBO:0000247 - !!omap - id: s_1466 - name: sucrose @@ -9996,6 +11130,7 @@ - annotation: !!omap - chebi: CHEBI:17992 - kegg.compound: C00089 + - sbo: SBO:0000247 - !!omap - id: s_1467 - name: sulphate @@ -10005,6 +11140,7 @@ - annotation: !!omap - chebi: CHEBI:16189 - kegg.compound: C00059 + - sbo: SBO:0000247 - !!omap - id: s_1468 - name: sulphate @@ -10014,6 +11150,7 @@ - annotation: !!omap - chebi: CHEBI:16189 - kegg.compound: C00059 + - sbo: SBO:0000247 - !!omap - id: s_1469 - name: sulphite @@ -10023,6 +11160,7 @@ - annotation: !!omap - chebi: CHEBI:17137 - kegg.compound: C11481 + - sbo: SBO:0000247 - !!omap - id: s_1470 - name: sulphite @@ -10032,6 +11170,7 @@ - annotation: !!omap - chebi: CHEBI:17137 - kegg.compound: C11481 + - sbo: SBO:0000247 - !!omap - id: s_1471 - name: taurine @@ -10041,6 +11180,7 @@ - annotation: !!omap - chebi: CHEBI:15891 - kegg.compound: C00245 + - sbo: SBO:0000247 - !!omap - id: s_1472 - name: taurine @@ -10050,6 +11190,7 @@ - annotation: !!omap - chebi: CHEBI:15891 - kegg.compound: C00245 + - sbo: SBO:0000247 - !!omap - id: s_1473 - name: taurocholic acid @@ -10059,6 +11200,7 @@ - annotation: !!omap - chebi: CHEBI:36257 - kegg.compound: C05122 + - sbo: SBO:0000247 - !!omap - id: s_1474 - name: taurocholic acid @@ -10068,6 +11210,7 @@ - annotation: !!omap - chebi: CHEBI:36257 - kegg.compound: C05122 + - sbo: SBO:0000247 - !!omap - id: s_1475 - name: TDP @@ -10077,6 +11220,7 @@ - annotation: !!omap - chebi: CHEBI:45931 - kegg.compound: C00068 + - sbo: SBO:0000247 - !!omap - id: s_1476 - name: TDP @@ -10086,6 +11230,7 @@ - annotation: !!omap - chebi: CHEBI:45931 - kegg.compound: C00068 + - sbo: SBO:0000247 - !!omap - id: s_1477 - name: TDP @@ -10095,6 +11240,7 @@ - annotation: !!omap - chebi: CHEBI:45931 - kegg.compound: C00068 + - sbo: SBO:0000247 - !!omap - id: s_1479 - name: tetracosanoyl-CoA @@ -10104,6 +11250,7 @@ - annotation: !!omap - chebi: CHEBI:52974 - kegg.compound: C16529 + - sbo: SBO:0000247 - !!omap - id: s_1480 - name: tetracosanoyl-CoA @@ -10113,6 +11260,7 @@ - annotation: !!omap - chebi: CHEBI:52974 - kegg.compound: C16529 + - sbo: SBO:0000247 - !!omap - id: s_1482 - name: tetracosanoyl-CoA @@ -10122,6 +11270,7 @@ - annotation: !!omap - chebi: CHEBI:52974 - kegg.compound: C16529 + - sbo: SBO:0000247 - !!omap - id: s_1483 - name: tetradecaprenyl diphosphate @@ -10130,6 +11279,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53039 + - sbo: SBO:0000247 - !!omap - id: s_1486 - name: tetrahydropteroyltri-L-glutamic acid @@ -10139,6 +11289,7 @@ - annotation: !!omap - chebi: CHEBI:58140 - kegg.compound: C04144 + - sbo: SBO:0000247 - !!omap - id: s_1487 - name: THF @@ -10148,6 +11299,7 @@ - annotation: !!omap - chebi: CHEBI:20506 - kegg.compound: C00101 + - sbo: SBO:0000247 - !!omap - id: s_1488 - name: THF @@ -10157,6 +11309,7 @@ - annotation: !!omap - chebi: CHEBI:20506 - kegg.compound: C00101 + - sbo: SBO:0000247 - !!omap - id: s_1489 - name: thiamine @@ -10166,6 +11319,7 @@ - annotation: !!omap - chebi: CHEBI:18385 - kegg.compound: C00378 + - sbo: SBO:0000247 - !!omap - id: s_1490 - name: thiamine @@ -10175,6 +11329,7 @@ - annotation: !!omap - chebi: CHEBI:18385 - kegg.compound: C00378 + - sbo: SBO:0000247 - !!omap - id: s_1491 - name: Thr-tRNA(Thr) @@ -10184,6 +11339,7 @@ - annotation: !!omap - chebi: CHEBI:29163 - kegg.compound: C02992 + - sbo: SBO:0000247 - !!omap - id: s_1492 - name: Thr-tRNA(Thr) @@ -10193,6 +11349,7 @@ - annotation: !!omap - chebi: CHEBI:29163 - kegg.compound: C02992 + - sbo: SBO:0000247 - !!omap - id: s_1493 - name: thymidine @@ -10202,6 +11359,7 @@ - annotation: !!omap - chebi: CHEBI:17748 - kegg.compound: C00214 + - sbo: SBO:0000247 - !!omap - id: s_1494 - name: thymidine @@ -10211,6 +11369,7 @@ - annotation: !!omap - chebi: CHEBI:17748 - kegg.compound: C00214 + - sbo: SBO:0000247 - !!omap - id: s_1497 - name: TMP @@ -10220,6 +11379,7 @@ - annotation: !!omap - chebi: CHEBI:9533 - kegg.compound: C01081 + - sbo: SBO:0000247 - !!omap - id: s_1498 - name: TMP @@ -10229,6 +11389,7 @@ - annotation: !!omap - chebi: CHEBI:9533 - kegg.compound: C01081 + - sbo: SBO:0000247 - !!omap - id: s_1503 - name: trans-aconitate @@ -10238,6 +11399,7 @@ - annotation: !!omap - chebi: CHEBI:15708 - kegg.compound: C02341 + - sbo: SBO:0000247 - !!omap - id: s_1504 - name: trans-aconitate @@ -10247,6 +11409,7 @@ - annotation: !!omap - chebi: CHEBI:15708 - kegg.compound: C02341 + - sbo: SBO:0000247 - !!omap - id: s_1507 - name: trans-dec-2-enoyl-CoA @@ -10255,6 +11418,7 @@ - charge: -4 - annotation: !!omap - kegg.compound: C05275 + - sbo: SBO:0000247 - !!omap - id: s_1510 - name: trans-dodec-2-enoyl-CoA @@ -10263,6 +11427,7 @@ - charge: -4 - annotation: !!omap - kegg.compound: C03221 + - sbo: SBO:0000247 - !!omap - id: s_1513 - name: trans-hexacos-2-enoyl-CoA @@ -10271,6 +11436,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52975 + - sbo: SBO:0000247 - !!omap - id: s_1516 - name: trans-octadec-2-enoyl-CoA @@ -10280,6 +11446,7 @@ - annotation: !!omap - chebi: CHEBI:50570 - kegg.compound: C16218 + - sbo: SBO:0000247 - !!omap - id: s_1519 - name: trans-tetradec-2-enoyl-CoA @@ -10289,6 +11456,7 @@ - annotation: !!omap - chebi: CHEBI:61405 - kegg.compound: C05273 + - sbo: SBO:0000247 - !!omap - id: s_1520 - name: trehalose @@ -10298,6 +11466,7 @@ - annotation: !!omap - chebi: CHEBI:16551 - kegg.compound: C01083 + - sbo: SBO:0000247 - !!omap - id: s_1521 - name: trehalose @@ -10307,6 +11476,7 @@ - annotation: !!omap - chebi: CHEBI:16551 - kegg.compound: C01083 + - sbo: SBO:0000247 - !!omap - id: s_1522 - name: trehalose @@ -10316,6 +11486,7 @@ - annotation: !!omap - chebi: CHEBI:16551 - kegg.compound: C01083 + - sbo: SBO:0000247 - !!omap - id: s_1523 - name: tridecaprenyl diphosphate @@ -10324,6 +11495,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53040 + - sbo: SBO:0000247 - !!omap - id: s_1524 - name: triglyceride backbone @@ -10333,6 +11505,7 @@ - annotation: !!omap - chebi: CHEBI:17855 - kegg.compound: C00422 + - sbo: SBO:0000649 - !!omap - id: s_1526 - name: trimethylenediamine @@ -10342,6 +11515,7 @@ - annotation: !!omap - chebi: CHEBI:57484 - kegg.compound: C00986 + - sbo: SBO:0000247 - !!omap - id: s_1527 - name: Trp-tRNA(Trp) @@ -10351,6 +11525,7 @@ - annotation: !!omap - chebi: CHEBI:29159 - kegg.compound: C03512 + - sbo: SBO:0000247 - !!omap - id: s_1528 - name: Trp-tRNA(Trp) @@ -10360,6 +11535,7 @@ - annotation: !!omap - chebi: CHEBI:29159 - kegg.compound: C03512 + - sbo: SBO:0000247 - !!omap - id: s_1529 - name: tryptophol @@ -10369,6 +11545,7 @@ - annotation: !!omap - chebi: CHEBI:17890 - kegg.compound: C00955 + - sbo: SBO:0000247 - !!omap - id: s_1530 - name: tryptophol @@ -10378,6 +11555,7 @@ - annotation: !!omap - chebi: CHEBI:17890 - kegg.compound: C00955 + - sbo: SBO:0000247 - !!omap - id: s_1531 - name: tryptophol @@ -10387,6 +11565,7 @@ - annotation: !!omap - chebi: CHEBI:17890 - kegg.compound: C00955 + - sbo: SBO:0000247 - !!omap - id: s_1532 - name: thiamine(1+) triphosphate(4-) @@ -10396,6 +11575,7 @@ - annotation: !!omap - chebi: CHEBI:58938 - kegg.compound: C03028 + - sbo: SBO:0000247 - !!omap - id: s_1533 - name: Tyr-tRNA(Tyr) @@ -10405,6 +11585,7 @@ - annotation: !!omap - chebi: CHEBI:29161 - kegg.compound: C02839 + - sbo: SBO:0000247 - !!omap - id: s_1534 - name: Tyr-tRNA(Tyr) @@ -10414,6 +11595,7 @@ - annotation: !!omap - chebi: CHEBI:29161 - kegg.compound: C02839 + - sbo: SBO:0000247 - !!omap - id: s_1535 - name: ubiquinol-6 @@ -10423,6 +11605,7 @@ - annotation: !!omap - chebi: CHEBI:52970 - kegg.compound: C00390 + - sbo: SBO:0000247 - !!omap - id: s_1537 - name: ubiquinone-6 @@ -10432,6 +11615,7 @@ - annotation: !!omap - chebi: CHEBI:52971 - kegg.compound: C17568 + - sbo: SBO:0000247 - !!omap - id: s_1538 - name: UDP @@ -10441,6 +11625,7 @@ - annotation: !!omap - chebi: CHEBI:58223 - kegg.compound: C00015 + - sbo: SBO:0000247 - !!omap - id: s_1539 - name: UDP @@ -10450,6 +11635,7 @@ - annotation: !!omap - chebi: CHEBI:58223 - kegg.compound: C00015 + - sbo: SBO:0000247 - !!omap - id: s_1540 - name: UDP @@ -10459,6 +11645,7 @@ - annotation: !!omap - chebi: CHEBI:58223 - kegg.compound: C00015 + - sbo: SBO:0000247 - !!omap - id: s_1541 - name: UDP-D-galactose @@ -10468,6 +11655,7 @@ - annotation: !!omap - chebi: CHEBI:58439 - kegg.compound: C00052 + - sbo: SBO:0000247 - !!omap - id: s_1542 - name: UDP-D-galactose @@ -10477,6 +11665,7 @@ - annotation: !!omap - chebi: CHEBI:58439 - kegg.compound: C00052 + - sbo: SBO:0000247 - !!omap - id: s_1543 - name: UDP-D-glucose @@ -10486,6 +11675,7 @@ - annotation: !!omap - chebi: CHEBI:58367 - kegg.compound: C00029 + - sbo: SBO:0000247 - !!omap - id: s_1544 - name: UDP-N-acetyl-alpha-D-glucosamine @@ -10495,6 +11685,7 @@ - annotation: !!omap - chebi: CHEBI:57705 - kegg.compound: C00043 + - sbo: SBO:0000247 - !!omap - id: s_1545 - name: UMP @@ -10504,6 +11695,7 @@ - annotation: !!omap - chebi: CHEBI:57865 - kegg.compound: C00105 + - sbo: SBO:0000247 - !!omap - id: s_1546 - name: UMP @@ -10513,6 +11705,7 @@ - annotation: !!omap - chebi: CHEBI:57865 - kegg.compound: C00105 + - sbo: SBO:0000247 - !!omap - id: s_1547 - name: UMP @@ -10522,6 +11715,7 @@ - annotation: !!omap - chebi: CHEBI:57865 - kegg.compound: C00105 + - sbo: SBO:0000247 - !!omap - id: s_1548 - name: UMP @@ -10531,6 +11725,7 @@ - annotation: !!omap - chebi: CHEBI:57865 - kegg.compound: C00105 + - sbo: SBO:0000247 - !!omap - id: s_1549 - name: undecaprenyl diphosphate @@ -10540,6 +11735,7 @@ - annotation: !!omap - chebi: CHEBI:53042 - kegg.compound: C03543 + - sbo: SBO:0000247 - !!omap - id: s_1550 - name: uracil @@ -10549,6 +11745,7 @@ - annotation: !!omap - chebi: CHEBI:17568 - kegg.compound: C00106 + - sbo: SBO:0000247 - !!omap - id: s_1551 - name: uracil @@ -10558,6 +11755,7 @@ - annotation: !!omap - chebi: CHEBI:17568 - kegg.compound: C00106 + - sbo: SBO:0000247 - !!omap - id: s_1552 - name: urea @@ -10567,6 +11765,7 @@ - annotation: !!omap - chebi: CHEBI:16199 - kegg.compound: C00086 + - sbo: SBO:0000247 - !!omap - id: s_1553 - name: urea @@ -10576,6 +11775,7 @@ - annotation: !!omap - chebi: CHEBI:16199 - kegg.compound: C00086 + - sbo: SBO:0000247 - !!omap - id: s_1554 - name: urea-1-carboxylic acid @@ -10585,6 +11785,7 @@ - annotation: !!omap - chebi: CHEBI:15832 - kegg.compound: C01010 + - sbo: SBO:0000247 - !!omap - id: s_1555 - name: ureidoglycolic acid @@ -10594,6 +11795,7 @@ - annotation: !!omap - chebi: CHEBI:49050 - kegg.compound: C05241 + - sbo: SBO:0000247 - !!omap - id: s_1556 - name: uridine @@ -10603,6 +11805,7 @@ - annotation: !!omap - chebi: CHEBI:16704 - kegg.compound: C00299 + - sbo: SBO:0000247 - !!omap - id: s_1557 - name: uridine @@ -10612,6 +11815,7 @@ - annotation: !!omap - chebi: CHEBI:16704 - kegg.compound: C00299 + - sbo: SBO:0000247 - !!omap - id: s_1558 - name: uroporphyrinogen III @@ -10621,6 +11825,7 @@ - annotation: !!omap - chebi: CHEBI:57308 - kegg.compound: C01051 + - sbo: SBO:0000247 - !!omap - id: s_1559 - name: UTP @@ -10630,6 +11835,7 @@ - annotation: !!omap - chebi: CHEBI:46398 - kegg.compound: C00075 + - sbo: SBO:0000247 - !!omap - id: s_1560 - name: UTP @@ -10639,6 +11845,7 @@ - annotation: !!omap - chebi: CHEBI:46398 - kegg.compound: C00075 + - sbo: SBO:0000247 - !!omap - id: s_1561 - name: Val-tRNA(Val) @@ -10648,6 +11855,7 @@ - annotation: !!omap - chebi: CHEBI:29164 - kegg.compound: C02554 + - sbo: SBO:0000247 - !!omap - id: s_1562 - name: Val-tRNA(Val) @@ -10657,6 +11865,7 @@ - annotation: !!omap - chebi: CHEBI:29164 - kegg.compound: C02554 + - sbo: SBO:0000247 - !!omap - id: s_1563 - name: xanthosine @@ -10666,6 +11875,7 @@ - annotation: !!omap - chebi: CHEBI:18107 - kegg.compound: C01762 + - sbo: SBO:0000247 - !!omap - id: s_1564 - name: xanthosine @@ -10675,6 +11885,7 @@ - annotation: !!omap - chebi: CHEBI:18107 - kegg.compound: C01762 + - sbo: SBO:0000247 - !!omap - id: s_1565 - name: xanthosine-5-phosphate @@ -10684,6 +11895,7 @@ - annotation: !!omap - chebi: CHEBI:57464 - kegg.compound: C00655 + - sbo: SBO:0000247 - !!omap - id: s_1566 - name: xylitol @@ -10693,6 +11905,7 @@ - annotation: !!omap - chebi: CHEBI:17151 - kegg.compound: C00379 + - sbo: SBO:0000247 - !!omap - id: s_1567 - name: xylitol @@ -10702,6 +11915,7 @@ - annotation: !!omap - chebi: CHEBI:17151 - kegg.compound: C00379 + - sbo: SBO:0000247 - !!omap - id: s_1568 - name: zymosterol @@ -10711,6 +11925,7 @@ - annotation: !!omap - chebi: CHEBI:18252 - kegg.compound: C05437 + - sbo: SBO:0000247 - !!omap - id: s_1569 - name: zymosterol @@ -10720,6 +11935,7 @@ - annotation: !!omap - chebi: CHEBI:18252 - kegg.compound: C05437 + - sbo: SBO:0000247 - !!omap - id: s_1571 - name: zymosterol @@ -10729,6 +11945,7 @@ - annotation: !!omap - chebi: CHEBI:18252 - kegg.compound: C05437 + - sbo: SBO:0000247 - !!omap - id: s_1572 - name: zymosterol @@ -10738,6 +11955,7 @@ - annotation: !!omap - chebi: CHEBI:18252 - kegg.compound: C05437 + - sbo: SBO:0000247 - !!omap - id: s_1576 - name: zymosterol intermediate 1a @@ -10746,6 +11964,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52388 + - sbo: SBO:0000247 - !!omap - id: s_1577 - name: zymosterol intermediate 1b @@ -10754,6 +11973,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52615 + - sbo: SBO:0000247 - !!omap - id: s_1578 - name: zymosterol intermediate 1c @@ -10762,6 +11982,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52389 + - sbo: SBO:0000247 - !!omap - id: s_1579 - name: zymosterol intermediate 2 @@ -10770,6 +11991,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52386 + - sbo: SBO:0000247 - !!omap - id: s_1582 - name: tRNA(Ala) @@ -10778,6 +12000,7 @@ - annotation: !!omap - chebi: CHEBI:29170 - kegg.compound: C01635 + - sbo: SBO:0000247 - !!omap - id: s_1583 - name: tRNA(Arg) @@ -10787,6 +12010,7 @@ - annotation: !!omap - chebi: CHEBI:29171 - kegg.compound: C01636 + - sbo: SBO:0000247 - !!omap - id: s_1584 - name: tRNA(Arg) @@ -10796,6 +12020,7 @@ - annotation: !!omap - chebi: CHEBI:29171 - kegg.compound: C01636 + - sbo: SBO:0000247 - !!omap - id: s_1585 - name: tRNA(Asn) @@ -10805,6 +12030,7 @@ - annotation: !!omap - chebi: CHEBI:29172 - kegg.compound: C01637 + - sbo: SBO:0000247 - !!omap - id: s_1586 - name: tRNA(Asn) @@ -10814,6 +12040,7 @@ - annotation: !!omap - chebi: CHEBI:29172 - kegg.compound: C01637 + - sbo: SBO:0000247 - !!omap - id: s_1587 - name: tRNA(Asp) @@ -10823,6 +12050,7 @@ - annotation: !!omap - chebi: CHEBI:29186 - kegg.compound: C01638 + - sbo: SBO:0000247 - !!omap - id: s_1588 - name: tRNA(Asp) @@ -10832,6 +12060,7 @@ - annotation: !!omap - chebi: CHEBI:29186 - kegg.compound: C01638 + - sbo: SBO:0000247 - !!omap - id: s_1589 - name: tRNA(Cys) @@ -10840,6 +12069,7 @@ - annotation: !!omap - chebi: CHEBI:29167 - kegg.compound: C01639 + - sbo: SBO:0000247 - !!omap - id: s_1590 - name: tRNA(Gln) @@ -10848,6 +12078,7 @@ - annotation: !!omap - chebi: CHEBI:29168 - kegg.compound: C01640 + - sbo: SBO:0000247 - !!omap - id: s_1591 - name: tRNA(Glu) @@ -10857,6 +12088,7 @@ - annotation: !!omap - chebi: CHEBI:29175 - kegg.compound: C01641 + - sbo: SBO:0000247 - !!omap - id: s_1592 - name: tRNA(Glu) @@ -10866,6 +12098,7 @@ - annotation: !!omap - chebi: CHEBI:29175 - kegg.compound: C01641 + - sbo: SBO:0000247 - !!omap - id: s_1593 - name: tRNA(Gly) @@ -10874,6 +12107,7 @@ - annotation: !!omap - chebi: CHEBI:29176 - kegg.compound: C01642 + - sbo: SBO:0000247 - !!omap - id: s_1594 - name: tRNA(His) @@ -10883,6 +12117,7 @@ - annotation: !!omap - chebi: CHEBI:29178 - kegg.compound: C01643 + - sbo: SBO:0000247 - !!omap - id: s_1595 - name: tRNA(His) @@ -10892,6 +12127,7 @@ - annotation: !!omap - chebi: CHEBI:29178 - kegg.compound: C01643 + - sbo: SBO:0000247 - !!omap - id: s_1596 - name: tRNA(Ile) @@ -10901,6 +12137,7 @@ - annotation: !!omap - chebi: CHEBI:29174 - kegg.compound: C01644 + - sbo: SBO:0000247 - !!omap - id: s_1597 - name: tRNA(Ile) @@ -10910,6 +12147,7 @@ - annotation: !!omap - chebi: CHEBI:29174 - kegg.compound: C01644 + - sbo: SBO:0000247 - !!omap - id: s_1598 - name: tRNA(Leu) @@ -10919,6 +12157,7 @@ - annotation: !!omap - chebi: CHEBI:29169 - kegg.compound: C01645 + - sbo: SBO:0000247 - !!omap - id: s_1599 - name: tRNA(Leu) @@ -10928,6 +12167,7 @@ - annotation: !!omap - chebi: CHEBI:29169 - kegg.compound: C01645 + - sbo: SBO:0000247 - !!omap - id: s_1600 - name: tRNA(Lys) @@ -10937,6 +12177,7 @@ - annotation: !!omap - chebi: CHEBI:29185 - kegg.compound: C01646 + - sbo: SBO:0000247 - !!omap - id: s_1601 - name: tRNA(Lys) @@ -10946,6 +12187,7 @@ - annotation: !!omap - chebi: CHEBI:29185 - kegg.compound: C01646 + - sbo: SBO:0000247 - !!omap - id: s_1602 - name: tRNA(Met) @@ -10955,6 +12197,7 @@ - annotation: !!omap - chebi: CHEBI:29173 - kegg.compound: C01647 + - sbo: SBO:0000247 - !!omap - id: s_1603 - name: tRNA(Met) @@ -10964,6 +12207,7 @@ - annotation: !!omap - chebi: CHEBI:29173 - kegg.compound: C01647 + - sbo: SBO:0000247 - !!omap - id: s_1604 - name: tRNA(Phe) @@ -10973,6 +12217,7 @@ - annotation: !!omap - chebi: CHEBI:29184 - kegg.compound: C01648 + - sbo: SBO:0000247 - !!omap - id: s_1605 - name: tRNA(Phe) @@ -10982,6 +12227,7 @@ - annotation: !!omap - chebi: CHEBI:29184 - kegg.compound: C01648 + - sbo: SBO:0000247 - !!omap - id: s_1606 - name: tRNA(Pro) @@ -10990,6 +12236,7 @@ - annotation: !!omap - chebi: CHEBI:29177 - kegg.compound: C01649 + - sbo: SBO:0000247 - !!omap - id: s_1607 - name: tRNA(Ser) @@ -10998,6 +12245,7 @@ - annotation: !!omap - chebi: CHEBI:29179 - kegg.compound: C01650 + - sbo: SBO:0000247 - !!omap - id: s_1608 - name: tRNA(Thr) @@ -11007,6 +12255,7 @@ - annotation: !!omap - chebi: CHEBI:29180 - kegg.compound: C01651 + - sbo: SBO:0000247 - !!omap - id: s_1609 - name: tRNA(Thr) @@ -11016,6 +12265,7 @@ - annotation: !!omap - chebi: CHEBI:29180 - kegg.compound: C01651 + - sbo: SBO:0000247 - !!omap - id: s_1610 - name: tRNA(Trp) @@ -11025,6 +12275,7 @@ - annotation: !!omap - chebi: CHEBI:29181 - kegg.compound: C01652 + - sbo: SBO:0000247 - !!omap - id: s_1611 - name: tRNA(Trp) @@ -11034,6 +12285,7 @@ - annotation: !!omap - chebi: CHEBI:29181 - kegg.compound: C01652 + - sbo: SBO:0000247 - !!omap - id: s_1612 - name: tRNA(Tyr) @@ -11043,6 +12295,7 @@ - annotation: !!omap - chebi: CHEBI:29182 - kegg.compound: C00787 + - sbo: SBO:0000247 - !!omap - id: s_1613 - name: tRNA(Tyr) @@ -11052,6 +12305,7 @@ - annotation: !!omap - chebi: CHEBI:29182 - kegg.compound: C00787 + - sbo: SBO:0000247 - !!omap - id: s_1614 - name: tRNA(Val) @@ -11061,6 +12315,7 @@ - annotation: !!omap - chebi: CHEBI:29183 - kegg.compound: C01653 + - sbo: SBO:0000247 - !!omap - id: s_1615 - name: tRNA(Val) @@ -11070,6 +12325,7 @@ - annotation: !!omap - chebi: CHEBI:29183 - kegg.compound: C01653 + - sbo: SBO:0000247 - !!omap - id: s_1616 - name: TRX1 @@ -11079,6 +12335,7 @@ - annotation: !!omap - chebi: CHEBI:15967 - kegg.compound: C00342 + - sbo: SBO:0000247 - !!omap - id: s_1617 - name: TRX1 @@ -11088,6 +12345,7 @@ - annotation: !!omap - chebi: CHEBI:15967 - kegg.compound: C00342 + - sbo: SBO:0000247 - !!omap - id: s_1618 - name: TRX1 @@ -11097,6 +12355,7 @@ - annotation: !!omap - chebi: CHEBI:15967 - kegg.compound: C00342 + - sbo: SBO:0000247 - !!omap - id: s_1619 - name: TRX1 @@ -11106,6 +12365,7 @@ - annotation: !!omap - chebi: CHEBI:15967 - kegg.compound: C00342 + - sbo: SBO:0000247 - !!omap - id: s_1620 - name: TRX1 disulphide @@ -11115,6 +12375,7 @@ - annotation: !!omap - chebi: CHEBI:18191 - kegg.compound: C00343 + - sbo: SBO:0000247 - !!omap - id: s_1621 - name: TRX1 disulphide @@ -11124,6 +12385,7 @@ - annotation: !!omap - chebi: CHEBI:18191 - kegg.compound: C00343 + - sbo: SBO:0000247 - !!omap - id: s_1622 - name: TRX1 disulphide @@ -11133,6 +12395,7 @@ - annotation: !!omap - chebi: CHEBI:18191 - kegg.compound: C00343 + - sbo: SBO:0000247 - !!omap - id: s_1623 - name: TRX1 disulphide @@ -11142,6 +12405,7 @@ - annotation: !!omap - chebi: CHEBI:18191 - kegg.compound: C00343 + - sbo: SBO:0000247 - !!omap - id: s_1845 - name: ACP1 @@ -11150,6 +12414,7 @@ - annotation: !!omap - chebi: CHEBI:18359 - kegg.compound: C00229 + - sbo: SBO:0000247 - !!omap - id: s_2763 - name: kynurenic acid @@ -11159,6 +12424,7 @@ - annotation: !!omap - chebi: CHEBI:18344 - kegg.compound: C01717 + - sbo: SBO:0000247 - !!omap - id: s_2764 - name: quinaldic acid @@ -11168,6 +12434,7 @@ - annotation: !!omap - chebi: CHEBI:18386 - kegg.compound: C06325 + - sbo: SBO:0000247 - !!omap - id: s_2766 - name: 14-demethyllanosterol @@ -11177,6 +12444,7 @@ - annotation: !!omap - chebi: CHEBI:18364 - kegg.compound: C05108 + - sbo: SBO:0000247 - !!omap - id: s_2768 - name: ergosta-5,7,22,24(28)-tetraen-3beta-ol @@ -11186,6 +12454,7 @@ - annotation: !!omap - chebi: CHEBI:18249 - kegg.compound: C05440 + - sbo: SBO:0000247 - !!omap - id: s_2770 - name: acetoacetyl-ACP @@ -11195,6 +12464,7 @@ - annotation: !!omap - chebi: CHEBI:2393 - kegg.compound: C05744 + - sbo: SBO:0000247 - !!omap - id: s_2771 - name: butanoyl-ACP @@ -11204,6 +12474,7 @@ - annotation: !!omap - chebi: CHEBI:3247 - kegg.compound: C05745 + - sbo: SBO:0000247 - !!omap - id: s_2772 - name: 3-oxo-hexanoyl-ACP @@ -11213,6 +12484,7 @@ - annotation: !!omap - chebi: CHEBI:1642 - kegg.compound: C05746 + - sbo: SBO:0000247 - !!omap - id: s_2773 - name: hexanoyl-ACP @@ -11222,6 +12494,7 @@ - annotation: !!omap - chebi: CHEBI:5704 - kegg.compound: C05749 + - sbo: SBO:0000247 - !!omap - id: s_2774 - name: 3-oxo-octanoyl-ACP @@ -11231,6 +12504,7 @@ - annotation: !!omap - chebi: CHEBI:1646 - kegg.compound: C05750 + - sbo: SBO:0000247 - !!omap - id: s_2775 - name: 3-hydroxybutanoyl-ACP @@ -11238,6 +12512,7 @@ - charge: 0 - annotation: !!omap - kegg.compound: C04618 + - sbo: SBO:0000247 - !!omap - id: s_2776 - name: 3-hydroxyhexanoyl-ACP @@ -11247,6 +12522,7 @@ - annotation: !!omap - chebi: CHEBI:326 - kegg.compound: C05747 + - sbo: SBO:0000247 - !!omap - id: s_2777 - name: 3-hydroxyoctanoyl-ACP @@ -11256,6 +12532,7 @@ - annotation: !!omap - chebi: CHEBI:80387 - kegg.compound: C16220 + - sbo: SBO:0000247 - !!omap - id: s_2778 - name: trans-but-2-enoyl-ACP @@ -11263,6 +12540,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:132146 + - sbo: SBO:0000247 - !!omap - id: s_2779 - name: trans-hex-2-enoyl-ACP @@ -11271,6 +12549,7 @@ - annotation: !!omap - chebi: CHEBI:10727 - kegg.compound: C05748 + - sbo: SBO:0000247 - !!omap - id: s_2780 - name: trans-oct-2-enoyl-ACP @@ -11278,6 +12557,7 @@ - charge: 0 - annotation: !!omap - kegg.compound: C05751 + - sbo: SBO:0000247 - !!omap - id: s_2781 - name: lauroyl-CoA @@ -11287,6 +12567,7 @@ - annotation: !!omap - chebi: CHEBI:57375 - kegg.compound: C01832 + - sbo: SBO:0000247 - !!omap - id: s_2782 - name: malonyl-CoA @@ -11296,6 +12577,7 @@ - annotation: !!omap - chebi: CHEBI:57384 - kegg.compound: C00083 + - sbo: SBO:0000247 - !!omap - id: s_2783 - name: H+ @@ -11305,6 +12587,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_2784 - name: carbon dioxide @@ -11314,6 +12597,7 @@ - annotation: !!omap - chebi: CHEBI:16526 - kegg.compound: C00011 + - sbo: SBO:0000247 - !!omap - id: s_2785 - name: coenzyme A @@ -11323,6 +12607,7 @@ - annotation: !!omap - chebi: CHEBI:57287 - kegg.compound: C00010 + - sbo: SBO:0000247 - !!omap - id: s_2786 - name: 3-oxotetradecanoyl-CoA @@ -11332,6 +12617,7 @@ - annotation: !!omap - chebi: CHEBI:28726 - kegg.compound: C05261 + - sbo: SBO:0000247 - !!omap - id: s_2787 - name: myristoyl-CoA @@ -11341,6 +12627,7 @@ - annotation: !!omap - chebi: CHEBI:57385 - kegg.compound: C02593 + - sbo: SBO:0000247 - !!omap - id: s_2788 - name: 3-oxopalmitoyl-CoA @@ -11350,6 +12637,7 @@ - annotation: !!omap - chebi: CHEBI:57349 - kegg.compound: C05259 + - sbo: SBO:0000247 - !!omap - id: s_2789 - name: palmitoyl-CoA @@ -11359,6 +12647,7 @@ - annotation: !!omap - chebi: CHEBI:57379 - kegg.compound: C00154 + - sbo: SBO:0000247 - !!omap - id: s_2790 - name: 3-oxooctadecanoyl-CoA @@ -11368,6 +12657,7 @@ - annotation: !!omap - chebi: CHEBI:50571 - kegg.compound: C16216 + - sbo: SBO:0000247 - !!omap - id: s_2791 - name: stearoyl-CoA @@ -11377,6 +12667,7 @@ - annotation: !!omap - chebi: CHEBI:57394 - kegg.compound: C00412 + - sbo: SBO:0000247 - !!omap - id: s_2792 - name: 3-oxoicosanoyl-CoA @@ -11385,6 +12676,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52327 + - sbo: SBO:0000247 - !!omap - id: s_2793 - name: icosanoyl-CoA @@ -11394,6 +12686,7 @@ - annotation: !!omap - chebi: CHEBI:15527 - kegg.compound: C02041 + - sbo: SBO:0000247 - !!omap - id: s_2794 - name: 3-oxodocosanoyl-CoA @@ -11402,6 +12695,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52328 + - sbo: SBO:0000247 - !!omap - id: s_2795 - name: docosanoyl-CoA @@ -11411,6 +12705,7 @@ - annotation: !!omap - chebi: CHEBI:65088 - kegg.compound: C16528 + - sbo: SBO:0000247 - !!omap - id: s_2796 - name: 3-oxotetracosanoyl-CoA @@ -11419,6 +12714,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52329 + - sbo: SBO:0000247 - !!omap - id: s_2797 - name: tetracosanoyl-CoA @@ -11428,6 +12724,7 @@ - annotation: !!omap - chebi: CHEBI:52974 - kegg.compound: C16529 + - sbo: SBO:0000247 - !!omap - id: s_2798 - name: 3-oxohexacosanoyl-CoA @@ -11436,6 +12733,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52977 + - sbo: SBO:0000247 - !!omap - id: s_2799 - name: NADPH @@ -11445,6 +12743,7 @@ - annotation: !!omap - chebi: CHEBI:57783 - kegg.compound: C00005 + - sbo: SBO:0000247 - !!omap - id: s_2800 - name: NADP(+) @@ -11454,6 +12753,7 @@ - annotation: !!omap - chebi: CHEBI:58349 - kegg.compound: C00006 + - sbo: SBO:0000247 - !!omap - id: s_2801 - name: (S)-3-hydroxytetradecanoyl-CoA @@ -11463,6 +12763,7 @@ - annotation: !!omap - chebi: CHEBI:27466 - kegg.compound: C05260 + - sbo: SBO:0000247 - !!omap - id: s_2802 - name: (S)-3-hydroxypalmitoyl-CoA @@ -11472,6 +12773,7 @@ - annotation: !!omap - chebi: CHEBI:27402 - kegg.compound: C05258 + - sbo: SBO:0000247 - !!omap - id: s_2803 - name: 3-hydroxyoctadecanoyl-CoA @@ -11481,6 +12783,7 @@ - annotation: !!omap - chebi: CHEBI:50583 - kegg.compound: C16217 + - sbo: SBO:0000247 - !!omap - id: s_2804 - name: 3-hydroxyicosanoyl-CoA @@ -11489,6 +12792,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52324 + - sbo: SBO:0000247 - !!omap - id: s_2805 - name: 3-hydroxydocosanoyl-CoA @@ -11497,6 +12801,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52325 + - sbo: SBO:0000247 - !!omap - id: s_2806 - name: 3-hydroxytetracosanoyl-CoA @@ -11505,6 +12810,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52326 + - sbo: SBO:0000247 - !!omap - id: s_2807 - name: (S)-3-hydroxyhexacosanoyl-CoA @@ -11513,6 +12819,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52976 + - sbo: SBO:0000247 - !!omap - id: s_2808 - name: H2O @@ -11522,6 +12829,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_2809 - name: trans-tetradec-2-enoyl-CoA @@ -11531,6 +12839,7 @@ - annotation: !!omap - chebi: CHEBI:61405 - kegg.compound: C05273 + - sbo: SBO:0000247 - !!omap - id: s_2810 - name: trans-hexadec-2-enoyl-CoA @@ -11539,6 +12848,7 @@ - charge: 0 - annotation: !!omap - kegg.compound: C05272 + - sbo: SBO:0000247 - !!omap - id: s_2811 - name: trans-octadec-2-enoyl-CoA @@ -11548,17 +12858,22 @@ - annotation: !!omap - chebi: CHEBI:50570 - kegg.compound: C16218 + - sbo: SBO:0000247 - !!omap - id: s_2812 - name: trans-icos-2-enoyl-CoA - compartment: erm - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2813 - name: trans-docos-2-enoyl-CoA - compartment: erm - formula: C33H56N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2814 - name: trans-tetracos-2-enoyl-CoA @@ -11567,6 +12882,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75068 + - sbo: SBO:0000247 - !!omap - id: s_2815 - name: trans-hexacos-2-enoyl-CoA @@ -11575,6 +12891,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52975 + - sbo: SBO:0000247 - !!omap - id: s_2816 - name: hexacosanoyl-CoA @@ -11583,6 +12900,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52966 + - sbo: SBO:0000247 - !!omap - id: s_2817 - name: oxygen @@ -11592,6 +12910,7 @@ - annotation: !!omap - chebi: CHEBI:15379 - kegg.compound: C00007 + - sbo: SBO:0000247 - !!omap - id: s_2818 - name: NADH @@ -11601,6 +12920,7 @@ - annotation: !!omap - chebi: CHEBI:57945 - kegg.compound: C00004 + - sbo: SBO:0000247 - !!omap - id: s_2819 - name: palmitoleoyl-CoA(4-) @@ -11610,6 +12930,7 @@ - annotation: !!omap - chebi: CHEBI:61540 - kegg.compound: C21072 + - sbo: SBO:0000247 - !!omap - id: s_2820 - name: NAD @@ -11619,6 +12940,7 @@ - annotation: !!omap - chebi: CHEBI:57540 - kegg.compound: C00003 + - sbo: SBO:0000247 - !!omap - id: s_2821 - name: oleoyl-CoA @@ -11628,6 +12950,7 @@ - annotation: !!omap - chebi: CHEBI:57387 - kegg.compound: C00510 + - sbo: SBO:0000247 - !!omap - id: s_2822 - name: butyrate @@ -11637,6 +12960,7 @@ - annotation: !!omap - chebi: CHEBI:17968 - kegg.compound: C00246 + - sbo: SBO:0000247 - !!omap - id: s_2824 - name: hexanoate @@ -11646,6 +12970,7 @@ - annotation: !!omap - chebi: CHEBI:17120 - kegg.compound: C01585 + - sbo: SBO:0000247 - !!omap - id: s_2826 - name: oleate @@ -11655,6 +12980,7 @@ - annotation: !!omap - chebi: CHEBI:30823 - kegg.compound: C00712 + - sbo: SBO:0000247 - !!omap - id: s_2828 - name: butyrate @@ -11664,6 +12990,7 @@ - annotation: !!omap - chebi: CHEBI:17968 - kegg.compound: C00246 + - sbo: SBO:0000247 - !!omap - id: s_2829 - name: hexanoate @@ -11673,6 +13000,7 @@ - annotation: !!omap - chebi: CHEBI:17120 - kegg.compound: C01585 + - sbo: SBO:0000247 - !!omap - id: s_2831 - name: ATP @@ -11682,6 +13010,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_2832 - name: laurate @@ -11691,6 +13020,7 @@ - annotation: !!omap - chebi: CHEBI:18262 - kegg.compound: C02679 + - sbo: SBO:0000247 - !!omap - id: s_2833 - name: AMP @@ -11700,6 +13030,7 @@ - annotation: !!omap - chebi: CHEBI:456215 - kegg.compound: C00020 + - sbo: SBO:0000247 - !!omap - id: s_2834 - name: diphosphate @@ -11709,6 +13040,7 @@ - annotation: !!omap - chebi: CHEBI:33019 - kegg.compound: C00013 + - sbo: SBO:0000247 - !!omap - id: s_2835 - name: myristate @@ -11718,6 +13050,7 @@ - annotation: !!omap - chebi: CHEBI:30807 - kegg.compound: C06424 + - sbo: SBO:0000247 - !!omap - id: s_2836 - name: palmitate @@ -11727,6 +13060,7 @@ - annotation: !!omap - chebi: CHEBI:7896 - kegg.compound: C00249 + - sbo: SBO:0000247 - !!omap - id: s_2837 - name: palmitoleate @@ -11736,6 +13070,7 @@ - annotation: !!omap - chebi: CHEBI:32372 - kegg.compound: C08362 + - sbo: SBO:0000247 - !!omap - id: s_2838 - name: stearate @@ -11745,6 +13080,7 @@ - annotation: !!omap - chebi: CHEBI:25629 - kegg.compound: C01530 + - sbo: SBO:0000247 - !!omap - id: s_2839 - name: oleate @@ -11754,6 +13090,7 @@ - annotation: !!omap - chebi: CHEBI:30823 - kegg.compound: C00712 + - sbo: SBO:0000247 - !!omap - id: s_2840 - name: ATP @@ -11763,6 +13100,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_2841 - name: laurate @@ -11772,6 +13110,7 @@ - annotation: !!omap - chebi: CHEBI:18262 - kegg.compound: C02679 + - sbo: SBO:0000247 - !!omap - id: s_2842 - name: AMP @@ -11781,6 +13120,7 @@ - annotation: !!omap - chebi: CHEBI:456215 - kegg.compound: C00020 + - sbo: SBO:0000247 - !!omap - id: s_2843 - name: lauroyl-CoA @@ -11790,6 +13130,7 @@ - annotation: !!omap - chebi: CHEBI:57375 - kegg.compound: C01832 + - sbo: SBO:0000247 - !!omap - id: s_2844 - name: myristate @@ -11799,6 +13140,7 @@ - annotation: !!omap - chebi: CHEBI:30807 - kegg.compound: C06424 + - sbo: SBO:0000247 - !!omap - id: s_2845 - name: myristoyl-CoA @@ -11808,6 +13150,7 @@ - annotation: !!omap - chebi: CHEBI:57385 - kegg.compound: C02593 + - sbo: SBO:0000247 - !!omap - id: s_2846 - name: palmitate @@ -11817,6 +13160,7 @@ - annotation: !!omap - chebi: CHEBI:7896 - kegg.compound: C00249 + - sbo: SBO:0000247 - !!omap - id: s_2847 - name: palmitoyl-CoA @@ -11826,6 +13170,7 @@ - annotation: !!omap - chebi: CHEBI:57379 - kegg.compound: C00154 + - sbo: SBO:0000247 - !!omap - id: s_2848 - name: palmitoleate @@ -11835,6 +13180,7 @@ - annotation: !!omap - chebi: CHEBI:32372 - kegg.compound: C08362 + - sbo: SBO:0000247 - !!omap - id: s_2849 - name: palmitoleoyl-CoA(4-) @@ -11844,6 +13190,7 @@ - annotation: !!omap - chebi: CHEBI:61540 - kegg.compound: C21072 + - sbo: SBO:0000247 - !!omap - id: s_2850 - name: stearate @@ -11853,6 +13200,7 @@ - annotation: !!omap - chebi: CHEBI:25629 - kegg.compound: C01530 + - sbo: SBO:0000247 - !!omap - id: s_2851 - name: stearoyl-CoA @@ -11862,6 +13210,7 @@ - annotation: !!omap - chebi: CHEBI:57394 - kegg.compound: C00412 + - sbo: SBO:0000247 - !!omap - id: s_2852 - name: oleate @@ -11871,6 +13220,7 @@ - annotation: !!omap - chebi: CHEBI:30823 - kegg.compound: C00712 + - sbo: SBO:0000247 - !!omap - id: s_2853 - name: oleoyl-CoA @@ -11880,6 +13230,7 @@ - annotation: !!omap - chebi: CHEBI:57387 - kegg.compound: C00510 + - sbo: SBO:0000247 - !!omap - id: s_2854 - name: palmitoleoyl-CoA(4-) @@ -11889,6 +13240,7 @@ - annotation: !!omap - chebi: CHEBI:61540 - kegg.compound: C21072 + - sbo: SBO:0000247 - !!omap - id: s_2855 - name: oleate @@ -11898,6 +13250,7 @@ - annotation: !!omap - chebi: CHEBI:30823 - kegg.compound: C00712 + - sbo: SBO:0000247 - !!omap - id: s_2856 - name: ATP @@ -11907,6 +13260,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_2857 - name: coenzyme A @@ -11916,6 +13270,7 @@ - annotation: !!omap - chebi: CHEBI:57287 - kegg.compound: C00010 + - sbo: SBO:0000247 - !!omap - id: s_2858 - name: arachidate @@ -11924,6 +13279,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:32360 + - sbo: SBO:0000247 - !!omap - id: s_2859 - name: AMP @@ -11933,6 +13289,7 @@ - annotation: !!omap - chebi: CHEBI:456215 - kegg.compound: C00020 + - sbo: SBO:0000247 - !!omap - id: s_2860 - name: diphosphate @@ -11942,6 +13299,7 @@ - annotation: !!omap - chebi: CHEBI:33019 - kegg.compound: C00013 + - sbo: SBO:0000247 - !!omap - id: s_2861 - name: icosanoyl-CoA @@ -11951,6 +13309,7 @@ - annotation: !!omap - chebi: CHEBI:15527 - kegg.compound: C02041 + - sbo: SBO:0000247 - !!omap - id: s_2862 - name: behenate @@ -11960,6 +13319,7 @@ - annotation: !!omap - chebi: CHEBI:23858 - kegg.compound: C08281 + - sbo: SBO:0000247 - !!omap - id: s_2863 - name: docosanoyl-CoA @@ -11969,6 +13329,7 @@ - annotation: !!omap - chebi: CHEBI:65088 - kegg.compound: C16528 + - sbo: SBO:0000247 - !!omap - id: s_2864 - name: lignoceric acid @@ -11978,6 +13339,7 @@ - annotation: !!omap - chebi: CHEBI:31014 - kegg.compound: C08320 + - sbo: SBO:0000247 - !!omap - id: s_2865 - name: tetracosanoyl-CoA @@ -11987,6 +13349,7 @@ - annotation: !!omap - chebi: CHEBI:52974 - kegg.compound: C16529 + - sbo: SBO:0000247 - !!omap - id: s_2866 - name: cerotic acid @@ -11995,6 +13358,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:31013 + - sbo: SBO:0000247 - !!omap - id: s_2867 - name: hexacosanoyl-CoA @@ -12003,6 +13367,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52966 + - sbo: SBO:0000247 - !!omap - id: s_2868 - name: behenate @@ -12012,6 +13377,7 @@ - annotation: !!omap - chebi: CHEBI:23858 - kegg.compound: C08281 + - sbo: SBO:0000247 - !!omap - id: s_2869 - name: lignoceric acid @@ -12021,6 +13387,7 @@ - annotation: !!omap - chebi: CHEBI:31014 - kegg.compound: C08320 + - sbo: SBO:0000247 - !!omap - id: s_2870 - name: cerotic acid @@ -12029,6 +13396,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:31013 + - sbo: SBO:0000247 - !!omap - id: s_2871 - name: behenate @@ -12038,6 +13406,7 @@ - annotation: !!omap - chebi: CHEBI:23858 - kegg.compound: C08281 + - sbo: SBO:0000247 - !!omap - id: s_2872 - name: docosanoyl-CoA @@ -12047,6 +13416,7 @@ - annotation: !!omap - chebi: CHEBI:65088 - kegg.compound: C16528 + - sbo: SBO:0000247 - !!omap - id: s_2873 - name: lignoceric acid @@ -12056,6 +13426,7 @@ - annotation: !!omap - chebi: CHEBI:31014 - kegg.compound: C08320 + - sbo: SBO:0000247 - !!omap - id: s_2874 - name: tetracosanoyl-CoA @@ -12065,6 +13436,7 @@ - annotation: !!omap - chebi: CHEBI:52974 - kegg.compound: C16529 + - sbo: SBO:0000247 - !!omap - id: s_2875 - name: cerotic acid @@ -12073,6 +13445,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:31013 + - sbo: SBO:0000247 - !!omap - id: s_2876 - name: hexacosanoyl-CoA @@ -12081,6 +13454,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52966 + - sbo: SBO:0000247 - !!omap - id: s_2877 - name: palmitoleoyl-CoA(4-) @@ -12090,6 +13464,7 @@ - annotation: !!omap - chebi: CHEBI:61540 - kegg.compound: C21072 + - sbo: SBO:0000247 - !!omap - id: s_2878 - name: icosanoyl-CoA @@ -12099,6 +13474,7 @@ - annotation: !!omap - chebi: CHEBI:15527 - kegg.compound: C02041 + - sbo: SBO:0000247 - !!omap - id: s_2879 - name: icosanoyl-CoA @@ -12108,6 +13484,7 @@ - annotation: !!omap - chebi: CHEBI:15527 - kegg.compound: C02041 + - sbo: SBO:0000247 - !!omap - id: s_2880 - name: docosanoyl-CoA @@ -12117,6 +13494,7 @@ - annotation: !!omap - chebi: CHEBI:65088 - kegg.compound: C16528 + - sbo: SBO:0000247 - !!omap - id: s_2881 - name: docosanoyl-CoA @@ -12126,6 +13504,7 @@ - annotation: !!omap - chebi: CHEBI:65088 - kegg.compound: C16528 + - sbo: SBO:0000247 - !!omap - id: s_2882 - name: butyrate @@ -12135,6 +13514,7 @@ - annotation: !!omap - chebi: CHEBI:17968 - kegg.compound: C00246 + - sbo: SBO:0000247 - !!omap - id: s_2883 - name: hexanoate @@ -12144,6 +13524,7 @@ - annotation: !!omap - chebi: CHEBI:17120 - kegg.compound: C01585 + - sbo: SBO:0000247 - !!omap - id: s_2884 - name: butanoyl-CoA @@ -12153,6 +13534,7 @@ - annotation: !!omap - chebi: CHEBI:15517 - kegg.compound: C00136 + - sbo: SBO:0000247 - !!omap - id: s_2885 - name: hexanoyl-CoA @@ -12162,6 +13544,7 @@ - annotation: !!omap - chebi: CHEBI:27540 - kegg.compound: C05270 + - sbo: SBO:0000247 - !!omap - id: s_2886 - name: but-2-enoyl-CoA @@ -12171,6 +13554,7 @@ - annotation: !!omap - chebi: CHEBI:36926 - kegg.compound: C00877 + - sbo: SBO:0000247 - !!omap - id: s_2887 - name: trans-hex-2-enoyl-CoA @@ -12180,6 +13564,7 @@ - annotation: !!omap - chebi: CHEBI:28706 - kegg.compound: C05271 + - sbo: SBO:0000247 - !!omap - id: s_2888 - name: trans-oct-2-enoyl-CoA @@ -12189,17 +13574,22 @@ - annotation: !!omap - chebi: CHEBI:27537 - kegg.compound: C05276 + - sbo: SBO:0000247 - !!omap - id: s_2889 - name: trans-icos-2-enoyl-CoA - compartment: p - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2890 - name: trans-docos-2-enoyl-CoA - compartment: p - formula: C33H56N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2891 - name: trans-tetracos-2-enoyl-CoA @@ -12208,6 +13598,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75068 + - sbo: SBO:0000247 - !!omap - id: s_2892 - name: trans-2,cis-9-hexadecadienoyl-CoA @@ -12216,12 +13607,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:76889 + - sbo: SBO:0000247 - !!omap - id: s_2893 - name: cis-tetradec-7-enoyl-CoA - compartment: p - formula: C35H60N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2894 - name: trans-2,cis-7-tetradecadienoyl-CoA @@ -12230,17 +13624,22 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88067 + - sbo: SBO:0000247 - !!omap - id: s_2895 - name: cis-dodec-5-enoyl-CoA - compartment: p - formula: C33H56N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2896 - name: trans-2,cis-5-dodecadienoyl-CoA - compartment: p - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2897 - name: trans-2,cis-9-octadecadienoyl-CoA @@ -12250,6 +13649,7 @@ - annotation: !!omap - chebi: CHEBI:15530 - kegg.compound: C02050 + - sbo: SBO:0000247 - !!omap - id: s_2898 - name: cis-hexadec-7-enoyl-CoA @@ -12258,6 +13658,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88008 + - sbo: SBO:0000247 - !!omap - id: s_2899 - name: trans-2,cis-7-hexadecadienoyl-CoA @@ -12266,6 +13667,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88086 + - sbo: SBO:0000247 - !!omap - id: s_2900 - name: cis-tetradec-5-enoyl-CoA @@ -12274,12 +13676,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:70712 + - sbo: SBO:0000247 - !!omap - id: s_2901 - name: trans-2,cis-5-tetradecadienoyl-CoA - compartment: p - formula: C35H58N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2902 - name: (R)-3-hydroxybutanoyl-CoA @@ -12289,6 +13694,7 @@ - annotation: !!omap - chebi: CHEBI:15452 - kegg.compound: C03561 + - sbo: SBO:0000247 - !!omap - id: s_2903 - name: (R)-3-hydroxyhexanoyl-CoA @@ -12297,6 +13703,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74474 + - sbo: SBO:0000247 - !!omap - id: s_2904 - name: (R)-3-hydroxyoctanoyl-CoA @@ -12305,6 +13712,7 @@ - annotation: !!omap - chebi: CHEBI:28573 - kegg.compound: C05278 + - sbo: SBO:0000247 - !!omap - id: s_2905 - name: (R)-3-hydroxyicosanoyl-CoA @@ -12313,6 +13721,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:76453 + - sbo: SBO:0000247 - !!omap - id: s_2906 - name: (R)-3-hydroxydocosanoyl-CoA @@ -12321,6 +13730,7 @@ - charge: -4 - annotation: !!omap - chebi: CHEBI:76375 + - sbo: SBO:0000247 - !!omap - id: s_2907 - name: (R)-3-hydroxytetracosanoyl-CoA @@ -12329,22 +13739,29 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:76463 + - sbo: SBO:0000247 - !!omap - id: s_2908 - name: (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA - compartment: p - formula: C39H68N7O18P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2909 - name: (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA - compartment: p - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2910 - name: (R)-3-hydroxy-cis-dodec-5-enoyl-CoA - compartment: p - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2911 - name: (R)-3-hydroxy-cis-octadec-9-enoyl-CoA @@ -12353,6 +13770,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:87781 + - sbo: SBO:0000247 - !!omap - id: s_2912 - name: (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA @@ -12361,6 +13779,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88087 + - sbo: SBO:0000247 - !!omap - id: s_2913 - name: (R)-3-hydroxy-cis-tetradec-5-enoyl-CoA @@ -12369,6 +13788,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88072 + - sbo: SBO:0000247 - !!omap - id: s_2914 - name: acetoacetyl-CoA @@ -12378,6 +13798,7 @@ - annotation: !!omap - chebi: CHEBI:57286 - kegg.compound: C00332 + - sbo: SBO:0000247 - !!omap - id: s_2915 - name: 3-oxohexanoyl-CoA @@ -12387,6 +13808,7 @@ - annotation: !!omap - chebi: CHEBI:27648 - kegg.compound: C05269 + - sbo: SBO:0000247 - !!omap - id: s_2916 - name: 3-oxooctanoyl-CoA @@ -12396,6 +13818,7 @@ - annotation: !!omap - chebi: CHEBI:28264 - kegg.compound: C05267 + - sbo: SBO:0000247 - !!omap - id: s_2917 - name: 3-oxoicosanoyl-CoA @@ -12404,6 +13827,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52327 + - sbo: SBO:0000247 - !!omap - id: s_2918 - name: 3-oxodocosanoyl-CoA @@ -12412,6 +13836,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52328 + - sbo: SBO:0000247 - !!omap - id: s_2919 - name: 3-oxotetracosanoyl-CoA @@ -12420,6 +13845,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52329 + - sbo: SBO:0000247 - !!omap - id: s_2920 - name: 3-oxo-cis-hexadec-9-enoyl-CoA @@ -12428,17 +13854,22 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:53152 + - sbo: SBO:0000247 - !!omap - id: s_2921 - name: 3-oxo-cis-tetradec-7-enoyl-CoA - compartment: p - formula: C35H60N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2922 - name: 3-oxo-cis-dodec-5-enoyl-CoA - compartment: p - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2923 - name: 3-oxo-cis-octadec-9-enoyl-CoA @@ -12447,24 +13878,31 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:78146 + - sbo: SBO:0000247 - !!omap - id: s_2924 - name: 3-oxo-cis-hexadec-7-enoyl-CoA - compartment: p - formula: C37H64N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2925 - name: 3-oxo-cis-tetradec-5-enoyl-CoA - compartment: p - formula: C35H60N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2926 - name: cis-dec-3-enoyl-CoA - compartment: p - formula: C31H52N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2927 - name: cis-dodec-3-enoyl-CoA @@ -12473,6 +13911,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:27989 + - sbo: SBO:0000247 - !!omap - id: s_2928 - name: trans-3,cis-5-dodecadienoyl-CoA @@ -12481,12 +13920,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:139121 + - sbo: SBO:0000247 - !!omap - id: s_2929 - name: trans-dodec-3-enoyl-CoA - compartment: p - formula: C33H56N7O17P3S - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2930 - name: trans-3,cis-5-tetradecadienoyl-CoA @@ -12495,6 +13937,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:72001 + - sbo: SBO:0000247 - !!omap - id: s_2931 - name: trans-tetradec-3-enoyl-CoA @@ -12503,6 +13946,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88083 + - sbo: SBO:0000247 - !!omap - id: s_2932 - name: trans-2,trans-4-dodecadienoyl-CoA @@ -12512,6 +13956,7 @@ - annotation: !!omap - chebi: CHEBI:28002 - kegg.compound: C05280 + - sbo: SBO:0000247 - !!omap - id: s_2933 - name: trans-2,trans-4-tetradecadienoyl-CoA @@ -12520,6 +13965,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88084 + - sbo: SBO:0000247 - !!omap - id: s_2934 - name: glycerol 3-phosphate @@ -12529,6 +13975,7 @@ - annotation: !!omap - chebi: CHEBI:57597 - kegg.compound: C00093 + - sbo: SBO:0000247 - !!omap - id: s_2935 - name: 1-acyl-sn-glycerol 3-phosphate (16:0) @@ -12538,6 +13985,7 @@ - annotation: !!omap - chebi: CHEBI:15799 - kegg.compound: C04036 + - sbo: SBO:0000247 - !!omap - id: s_2936 - name: 1-acyl-sn-glycerol 3-phosphate (16:1) @@ -12546,6 +13994,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75070 + - sbo: SBO:0000247 - !!omap - id: s_2937 - name: 1-acyl-sn-glycerol 3-phosphate (18:0) @@ -12554,6 +14003,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74850 + - sbo: SBO:0000247 - !!omap - id: s_2938 - name: 1-acyl-sn-glycerol 3-phosphate (18:1) @@ -12562,6 +14012,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62837 + - sbo: SBO:0000247 - !!omap - id: s_2939 - name: dihydroxyacetone phosphate @@ -12571,6 +14022,7 @@ - annotation: !!omap - chebi: CHEBI:57642 - kegg.compound: C00111 + - sbo: SBO:0000247 - !!omap - id: s_2940 - name: acylglycerone phosphate (16:0) @@ -12580,6 +14032,7 @@ - annotation: !!omap - chebi: CHEBI:17868 - kegg.compound: C01192 + - sbo: SBO:0000247 - !!omap - id: s_2941 - name: acylglycerone phosphate (16:1) @@ -12588,6 +14041,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:74694 + - sbo: SBO:0000247 - !!omap - id: s_2942 - name: acylglycerone phosphate (18:0) @@ -12597,6 +14051,7 @@ - annotation: !!omap - chebi: CHEBI:36476 - kegg.compound: C03805 + - sbo: SBO:0000247 - !!omap - id: s_2943 - name: acylglycerone phosphate (18:1) @@ -12606,6 +14061,7 @@ - annotation: !!omap - chebi: CHEBI:36475 - kegg.compound: C03630 + - sbo: SBO:0000247 - !!omap - id: s_2944 - name: 1-acyl-sn-glycerol 3-phosphate (16:0) @@ -12615,6 +14071,7 @@ - annotation: !!omap - chebi: CHEBI:15799 - kegg.compound: C04036 + - sbo: SBO:0000247 - !!omap - id: s_2945 - name: 1-acyl-sn-glycerol 3-phosphate (16:1) @@ -12623,6 +14080,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75070 + - sbo: SBO:0000247 - !!omap - id: s_2946 - name: 1-acyl-sn-glycerol 3-phosphate (18:0) @@ -12631,6 +14089,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74850 + - sbo: SBO:0000247 - !!omap - id: s_2947 - name: 1-acyl-sn-glycerol 3-phosphate (18:1) @@ -12639,6 +14098,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62837 + - sbo: SBO:0000247 - !!omap - id: s_2948 - name: acylglycerone phosphate (16:0) @@ -12648,6 +14108,7 @@ - annotation: !!omap - chebi: CHEBI:17868 - kegg.compound: C01192 + - sbo: SBO:0000247 - !!omap - id: s_2949 - name: acylglycerone phosphate (16:1) @@ -12656,6 +14117,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:74694 + - sbo: SBO:0000247 - !!omap - id: s_2950 - name: acylglycerone phosphate (18:0) @@ -12665,6 +14127,7 @@ - annotation: !!omap - chebi: CHEBI:36476 - kegg.compound: C03805 + - sbo: SBO:0000247 - !!omap - id: s_2951 - name: acylglycerone phosphate (18:1) @@ -12674,6 +14137,7 @@ - annotation: !!omap - chebi: CHEBI:36475 - kegg.compound: C03630 + - sbo: SBO:0000247 - !!omap - id: s_2952 - name: NADPH @@ -12683,6 +14147,7 @@ - annotation: !!omap - chebi: CHEBI:57783 - kegg.compound: C00005 + - sbo: SBO:0000247 - !!omap - id: s_2953 - name: NADP(+) @@ -12692,6 +14157,7 @@ - annotation: !!omap - chebi: CHEBI:58349 - kegg.compound: C00006 + - sbo: SBO:0000247 - !!omap - id: s_2954 - name: phosphatidate (1-16:0, 2-16:1) @@ -12700,6 +14166,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:73998 + - sbo: SBO:0000247 - !!omap - id: s_2955 - name: phosphatidate (1-16:0, 2-18:1) @@ -12709,6 +14176,7 @@ - annotation: !!omap - chebi: CHEBI:64844 - kegg.compound: C13889 + - sbo: SBO:0000247 - !!omap - id: s_2956 - name: phosphatidate (1-16:1, 2-16:1) @@ -12717,12 +14185,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75071 + - sbo: SBO:0000247 - !!omap - id: s_2957 - name: phosphatidate (1-16:1, 2-18:1) - compartment: erm - formula: C37H69O8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2958 - name: phosphatidate (1-18:0, 2-16:1) @@ -12731,6 +14202,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75073 + - sbo: SBO:0000247 - !!omap - id: s_2959 - name: phosphatidate (1-18:0, 2-18:1) @@ -12739,6 +14211,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74847 + - sbo: SBO:0000247 - !!omap - id: s_2960 - name: phosphatidate (1-18:1, 2-16:1) @@ -12747,6 +14220,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75074 + - sbo: SBO:0000247 - !!omap - id: s_2961 - name: phosphatidate (1-18:1, 2-18:1) @@ -12755,6 +14229,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:83775 + - sbo: SBO:0000247 - !!omap - id: s_2962 - name: phosphatidate (1-16:0, 2-18:1) @@ -12764,12 +14239,15 @@ - annotation: !!omap - chebi: CHEBI:64844 - kegg.compound: C13889 + - sbo: SBO:0000247 - !!omap - id: s_2963 - name: phosphatidate (1-16:1, 2-18:1) - compartment: lp - formula: C37H69O8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2964 - name: phosphatidate (1-18:0, 2-18:1) @@ -12778,6 +14256,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74847 + - sbo: SBO:0000247 - !!omap - id: s_2965 - name: phosphatidate (1-18:1, 2-18:1) @@ -12786,6 +14265,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:83775 + - sbo: SBO:0000247 - !!omap - id: s_2966 - name: phosphate @@ -12795,6 +14275,7 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_2967 - name: diglyceride (1-16:0, 2-16:1) @@ -12803,6 +14284,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82929 + - sbo: SBO:0000247 - !!omap - id: s_2968 - name: diglyceride (1-16:0, 2-18:1) @@ -12811,6 +14293,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88454 + - sbo: SBO:0000247 - !!omap - id: s_2969 - name: diglyceride (1-16:1, 2-16:1) @@ -12819,6 +14302,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:84417 + - sbo: SBO:0000247 - !!omap - id: s_2970 - name: diglyceride (1-16:1, 2-18:1) @@ -12827,6 +14311,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88500 + - sbo: SBO:0000247 - !!omap - id: s_2971 - name: diglyceride (1-18:0, 2-16:1) @@ -12835,6 +14320,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88527 + - sbo: SBO:0000247 - !!omap - id: s_2972 - name: diglyceride (1-18:0, 2-18:1) @@ -12843,6 +14329,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75468 + - sbo: SBO:0000247 - !!omap - id: s_2973 - name: diglyceride (1-18:1, 2-16:1) @@ -12851,6 +14338,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89229 + - sbo: SBO:0000247 - !!omap - id: s_2974 - name: diglyceride (1-18:1, 2-18:1) @@ -12859,6 +14347,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52333 + - sbo: SBO:0000247 - !!omap - id: s_2975 - name: phosphatidate (1-16:0, 2-16:1) @@ -12867,6 +14356,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:73998 + - sbo: SBO:0000247 - !!omap - id: s_2976 - name: H2O @@ -12876,6 +14366,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_2977 - name: phosphate @@ -12885,6 +14376,7 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_2978 - name: diglyceride (1-16:0, 2-16:1) @@ -12893,6 +14385,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82929 + - sbo: SBO:0000247 - !!omap - id: s_2979 - name: phosphatidate (1-16:0, 2-18:1) @@ -12902,6 +14395,7 @@ - annotation: !!omap - chebi: CHEBI:64844 - kegg.compound: C13889 + - sbo: SBO:0000247 - !!omap - id: s_2980 - name: diglyceride (1-16:0, 2-18:1) @@ -12910,6 +14404,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88454 + - sbo: SBO:0000247 - !!omap - id: s_2981 - name: phosphatidate (1-16:1, 2-16:1) @@ -12918,6 +14413,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75071 + - sbo: SBO:0000247 - !!omap - id: s_2982 - name: diglyceride (1-16:1, 2-16:1) @@ -12926,12 +14422,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:84417 + - sbo: SBO:0000247 - !!omap - id: s_2983 - name: phosphatidate (1-16:1, 2-18:1) - compartment: vm - formula: C37H69O8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_2984 - name: diglyceride (1-16:1, 2-18:1) @@ -12940,6 +14439,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88500 + - sbo: SBO:0000247 - !!omap - id: s_2985 - name: phosphatidate (1-18:0, 2-16:1) @@ -12948,6 +14448,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75073 + - sbo: SBO:0000247 - !!omap - id: s_2986 - name: diglyceride (1-18:0, 2-16:1) @@ -12956,6 +14457,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88527 + - sbo: SBO:0000247 - !!omap - id: s_2987 - name: phosphatidate (1-18:0, 2-18:1) @@ -12964,6 +14466,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74847 + - sbo: SBO:0000247 - !!omap - id: s_2988 - name: diglyceride (1-18:0, 2-18:1) @@ -12972,6 +14475,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75468 + - sbo: SBO:0000247 - !!omap - id: s_2989 - name: phosphatidate (1-18:1, 2-16:1) @@ -12980,6 +14484,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75074 + - sbo: SBO:0000247 - !!omap - id: s_2990 - name: diglyceride (1-18:1, 2-16:1) @@ -12988,6 +14493,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89229 + - sbo: SBO:0000247 - !!omap - id: s_2991 - name: phosphatidate (1-18:1, 2-18:1) @@ -12996,6 +14502,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:83775 + - sbo: SBO:0000247 - !!omap - id: s_2992 - name: diglyceride (1-18:1, 2-18:1) @@ -13004,6 +14511,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52333 + - sbo: SBO:0000247 - !!omap - id: s_2993 - name: phosphatidate (1-16:0, 2-16:1) @@ -13012,6 +14520,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:73998 + - sbo: SBO:0000247 - !!omap - id: s_2994 - name: H2O @@ -13021,6 +14530,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_2995 - name: phosphate @@ -13030,6 +14540,7 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_2996 - name: diglyceride (1-16:0, 2-16:1) @@ -13038,6 +14549,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82929 + - sbo: SBO:0000247 - !!omap - id: s_2997 - name: phosphatidate (1-16:0, 2-18:1) @@ -13047,6 +14559,7 @@ - annotation: !!omap - chebi: CHEBI:64844 - kegg.compound: C13889 + - sbo: SBO:0000247 - !!omap - id: s_2998 - name: diglyceride (1-16:0, 2-18:1) @@ -13055,6 +14568,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88454 + - sbo: SBO:0000247 - !!omap - id: s_2999 - name: phosphatidate (1-16:1, 2-16:1) @@ -13063,6 +14577,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75071 + - sbo: SBO:0000247 - !!omap - id: s_3000 - name: diglyceride (1-16:1, 2-16:1) @@ -13071,12 +14586,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:84417 + - sbo: SBO:0000247 - !!omap - id: s_3001 - name: phosphatidate (1-16:1, 2-18:1) - compartment: gm - formula: C37H69O8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3002 - name: diglyceride (1-16:1, 2-18:1) @@ -13085,6 +14603,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88500 + - sbo: SBO:0000247 - !!omap - id: s_3003 - name: phosphatidate (1-18:0, 2-16:1) @@ -13093,6 +14612,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75073 + - sbo: SBO:0000247 - !!omap - id: s_3004 - name: diglyceride (1-18:0, 2-16:1) @@ -13101,6 +14621,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88527 + - sbo: SBO:0000247 - !!omap - id: s_3005 - name: phosphatidate (1-18:0, 2-18:1) @@ -13109,6 +14630,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74847 + - sbo: SBO:0000247 - !!omap - id: s_3006 - name: diglyceride (1-18:0, 2-18:1) @@ -13117,6 +14639,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75468 + - sbo: SBO:0000247 - !!omap - id: s_3007 - name: phosphatidate (1-18:1, 2-16:1) @@ -13125,6 +14648,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75074 + - sbo: SBO:0000247 - !!omap - id: s_3008 - name: diglyceride (1-18:1, 2-16:1) @@ -13133,6 +14657,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89229 + - sbo: SBO:0000247 - !!omap - id: s_3009 - name: phosphatidate (1-18:1, 2-18:1) @@ -13141,6 +14666,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:83775 + - sbo: SBO:0000247 - !!omap - id: s_3010 - name: diglyceride (1-18:1, 2-18:1) @@ -13149,6 +14675,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52333 + - sbo: SBO:0000247 - !!omap - id: s_3011 - name: triglyceride (1-16:0, 2-16:1, 3-16:0) @@ -13157,6 +14684,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:85427 + - sbo: SBO:0000247 - !!omap - id: s_3012 - name: triglyceride (1-16:0, 2-18:1, 3-16:0) @@ -13165,24 +14693,31 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89759 + - sbo: SBO:0000247 - !!omap - id: s_3013 - name: triglyceride (1-16:1, 2-16:1, 3-16:0) - compartment: erm - formula: C51H94O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3014 - name: triglyceride (1-16:1, 2-18:1, 3-16:0) - compartment: erm - formula: C53H98O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3015 - name: triglyceride (1-18:0, 2-16:1, 3-16:0) - compartment: erm - formula: C53H100O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3016 - name: triglyceride (1-18:0, 2-18:1, 3-16:0) @@ -13191,12 +14726,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89755 + - sbo: SBO:0000247 - !!omap - id: s_3017 - name: triglyceride (1-18:1, 2-16:1, 3-16:0) - compartment: erm - formula: C53H98O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3018 - name: triglyceride (1-18:1, 2-18:1, 3-16:0) @@ -13205,6 +14743,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88999 + - sbo: SBO:0000247 - !!omap - id: s_3019 - name: triglyceride (1-16:0, 2-16:1, 3-16:1) @@ -13213,12 +14752,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89765 + - sbo: SBO:0000247 - !!omap - id: s_3020 - name: triglyceride (1-16:0, 2-18:1, 3-16:1) - compartment: erm - formula: C53H98O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3021 - name: triglyceride (1-16:1, 2-16:1, 3-16:1) @@ -13227,12 +14769,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75841 + - sbo: SBO:0000247 - !!omap - id: s_3022 - name: triglyceride (1-16:1, 2-18:1, 3-16:1) - compartment: erm - formula: C53H96O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3023 - name: triglyceride (1-18:0, 2-16:1, 3-16:1) @@ -13241,24 +14786,31 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90053 + - sbo: SBO:0000247 - !!omap - id: s_3024 - name: triglyceride (1-18:0, 2-18:1, 3-16:1) - compartment: erm - formula: C55H102O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3025 - name: triglyceride (1-18:1, 2-16:1, 3-16:1) - compartment: erm - formula: C53H96O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3026 - name: triglyceride (1-18:1, 2-18:1, 3-16:1) - compartment: erm - formula: C55H100O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3027 - name: triglyceride (1-16:0, 2-16:1, 3-18:0) @@ -13267,6 +14819,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89763 + - sbo: SBO:0000247 - !!omap - id: s_3028 - name: triglyceride (1-16:0, 2-18:1, 3-18:0) @@ -13275,18 +14828,23 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88998 + - sbo: SBO:0000247 - !!omap - id: s_3029 - name: triglyceride (1-16:1, 2-16:1, 3-18:0) - compartment: erm - formula: C53H98O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3030 - name: triglyceride (1-16:1, 2-18:1, 3-18:0) - compartment: erm - formula: C55H102O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3031 - name: triglyceride (1-18:0, 2-16:1, 3-18:0) @@ -13295,6 +14853,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89958 + - sbo: SBO:0000247 - !!omap - id: s_3032 - name: triglyceride (1-18:0, 2-18:1, 3-18:0) @@ -13303,30 +14862,39 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90305 + - sbo: SBO:0000247 - !!omap - id: s_3033 - name: triglyceride (1-18:1, 2-16:1, 3-18:0) - compartment: erm - formula: C55H102O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3034 - name: triglyceride (1-18:1, 2-18:1, 3-18:0) - compartment: erm - formula: C57H106O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3035 - name: triglyceride (1-16:0, 2-16:1, 3-18:1) - compartment: erm - formula: C53H98O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3036 - name: triglyceride (1-16:0, 2-18:1, 3-18:1) - compartment: erm - formula: C55H102O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3037 - name: triglyceride (1-16:1, 2-16:1, 3-18:1) @@ -13335,6 +14903,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90051 + - sbo: SBO:0000247 - !!omap - id: s_3038 - name: triglyceride (1-16:1, 2-18:1, 3-18:1) @@ -13343,18 +14912,23 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90048 + - sbo: SBO:0000247 - !!omap - id: s_3039 - name: triglyceride (1-18:0, 2-16:1, 3-18:1) - compartment: erm - formula: C55H102O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3040 - name: triglyceride (1-18:0, 2-18:1, 3-18:1) - compartment: erm - formula: C57H106O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3041 - name: triglyceride (1-18:1, 2-16:1, 3-18:1) @@ -13363,6 +14937,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88984 + - sbo: SBO:0000247 - !!omap - id: s_3042 - name: triglyceride (1-18:1, 2-18:1, 3-18:1) @@ -13371,6 +14946,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88970 + - sbo: SBO:0000247 - !!omap - id: s_3043 - name: diglyceride (1-16:0, 2-16:1) @@ -13379,6 +14955,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82929 + - sbo: SBO:0000247 - !!omap - id: s_3044 - name: triglyceride (1-16:0, 2-16:1, 3-16:0) @@ -13387,6 +14964,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:85427 + - sbo: SBO:0000247 - !!omap - id: s_3045 - name: diglyceride (1-16:0, 2-18:1) @@ -13395,6 +14973,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88454 + - sbo: SBO:0000247 - !!omap - id: s_3046 - name: triglyceride (1-16:0, 2-18:1, 3-16:0) @@ -13403,6 +14982,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89759 + - sbo: SBO:0000247 - !!omap - id: s_3047 - name: diglyceride (1-16:1, 2-16:1) @@ -13411,12 +14991,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:84417 + - sbo: SBO:0000247 - !!omap - id: s_3048 - name: triglyceride (1-16:1, 2-16:1, 3-16:0) - compartment: lp - formula: C51H94O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3049 - name: diglyceride (1-16:1, 2-18:1) @@ -13425,12 +15008,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88500 + - sbo: SBO:0000247 - !!omap - id: s_3050 - name: triglyceride (1-16:1, 2-18:1, 3-16:0) - compartment: lp - formula: C53H98O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3051 - name: diglyceride (1-18:0, 2-16:1) @@ -13439,12 +15025,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88527 + - sbo: SBO:0000247 - !!omap - id: s_3052 - name: triglyceride (1-18:0, 2-16:1, 3-16:0) - compartment: lp - formula: C53H100O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3053 - name: diglyceride (1-18:0, 2-18:1) @@ -13453,6 +15042,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75468 + - sbo: SBO:0000247 - !!omap - id: s_3054 - name: triglyceride (1-18:0, 2-18:1, 3-16:0) @@ -13461,6 +15051,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89755 + - sbo: SBO:0000247 - !!omap - id: s_3055 - name: diglyceride (1-18:1, 2-16:1) @@ -13469,12 +15060,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89229 + - sbo: SBO:0000247 - !!omap - id: s_3056 - name: triglyceride (1-18:1, 2-16:1, 3-16:0) - compartment: lp - formula: C53H98O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3057 - name: diglyceride (1-18:1, 2-18:1) @@ -13483,6 +15077,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52333 + - sbo: SBO:0000247 - !!omap - id: s_3058 - name: triglyceride (1-18:1, 2-18:1, 3-16:0) @@ -13491,6 +15086,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88999 + - sbo: SBO:0000247 - !!omap - id: s_3059 - name: triglyceride (1-16:0, 2-16:1, 3-16:1) @@ -13499,12 +15095,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89765 + - sbo: SBO:0000247 - !!omap - id: s_3060 - name: triglyceride (1-16:0, 2-18:1, 3-16:1) - compartment: lp - formula: C53H98O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3061 - name: triglyceride (1-16:1, 2-16:1, 3-16:1) @@ -13513,12 +15112,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75841 + - sbo: SBO:0000247 - !!omap - id: s_3062 - name: triglyceride (1-16:1, 2-18:1, 3-16:1) - compartment: lp - formula: C53H96O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3063 - name: triglyceride (1-18:0, 2-16:1, 3-16:1) @@ -13527,24 +15129,31 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90053 + - sbo: SBO:0000247 - !!omap - id: s_3064 - name: triglyceride (1-18:0, 2-18:1, 3-16:1) - compartment: lp - formula: C55H102O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3065 - name: triglyceride (1-18:1, 2-16:1, 3-16:1) - compartment: lp - formula: C53H96O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3066 - name: triglyceride (1-18:1, 2-18:1, 3-16:1) - compartment: lp - formula: C55H100O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3067 - name: triglyceride (1-16:0, 2-16:1, 3-18:0) @@ -13553,6 +15162,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89763 + - sbo: SBO:0000247 - !!omap - id: s_3068 - name: triglyceride (1-16:0, 2-18:1, 3-18:0) @@ -13561,18 +15171,23 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88998 + - sbo: SBO:0000247 - !!omap - id: s_3069 - name: triglyceride (1-16:1, 2-16:1, 3-18:0) - compartment: lp - formula: C53H98O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3070 - name: triglyceride (1-16:1, 2-18:1, 3-18:0) - compartment: lp - formula: C55H102O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3071 - name: triglyceride (1-18:0, 2-16:1, 3-18:0) @@ -13581,6 +15196,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89958 + - sbo: SBO:0000247 - !!omap - id: s_3072 - name: triglyceride (1-18:0, 2-18:1, 3-18:0) @@ -13589,30 +15205,39 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90305 + - sbo: SBO:0000247 - !!omap - id: s_3073 - name: triglyceride (1-18:1, 2-16:1, 3-18:0) - compartment: lp - formula: C55H102O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3074 - name: triglyceride (1-18:1, 2-18:1, 3-18:0) - compartment: lp - formula: C57H106O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3075 - name: triglyceride (1-16:0, 2-16:1, 3-18:1) - compartment: lp - formula: C53H98O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3076 - name: triglyceride (1-16:0, 2-18:1, 3-18:1) - compartment: lp - formula: C55H102O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3077 - name: triglyceride (1-16:1, 2-16:1, 3-18:1) @@ -13621,6 +15246,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90051 + - sbo: SBO:0000247 - !!omap - id: s_3078 - name: triglyceride (1-16:1, 2-18:1, 3-18:1) @@ -13629,18 +15255,23 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90048 + - sbo: SBO:0000247 - !!omap - id: s_3079 - name: triglyceride (1-18:0, 2-16:1, 3-18:1) - compartment: lp - formula: C55H102O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3080 - name: triglyceride (1-18:0, 2-18:1, 3-18:1) - compartment: lp - formula: C57H106O6 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3081 - name: triglyceride (1-18:1, 2-16:1, 3-18:1) @@ -13649,6 +15280,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88984 + - sbo: SBO:0000247 - !!omap - id: s_3082 - name: triglyceride (1-18:1, 2-18:1, 3-18:1) @@ -13657,6 +15289,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88970 + - sbo: SBO:0000247 - !!omap - id: s_3083 - name: CTP @@ -13666,12 +15299,15 @@ - annotation: !!omap - chebi: CHEBI:37563 - kegg.compound: C00063 + - sbo: SBO:0000247 - !!omap - id: s_3084 - name: CDP-diacylglycerol (1-16:0, 2-16:1) - compartment: erm - formula: C44H79N3O15P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3085 - name: CDP-diacylglycerol (1-16:1, 2-16:1) @@ -13680,18 +15316,23 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:104012 + - sbo: SBO:0000247 - !!omap - id: s_3086 - name: CDP-diacylglycerol (1-18:0, 2-16:1) - compartment: erm - formula: C46H83N3O15P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3087 - name: CDP-diacylglycerol (1-18:1, 2-16:1) - compartment: erm - formula: C46H81N3O15P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3088 - name: CDP-diacylglycerol (1-16:0, 2-18:1) @@ -13701,18 +15342,23 @@ - annotation: !!omap - chebi: CHEBI:34077 - kegg.compound: C13892 + - sbo: SBO:0000247 - !!omap - id: s_3089 - name: CDP-diacylglycerol (1-16:1, 2-18:1) - compartment: erm - formula: C46H81N3O15P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3090 - name: CDP-diacylglycerol (1-18:0, 2-18:1) - compartment: erm - formula: C48H83N3O15P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3091 - name: CDP-diacylglycerol (1-18:1, 2-18:1) @@ -13721,6 +15367,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:104362 + - sbo: SBO:0000247 - !!omap - id: s_3092 - name: phosphatidate (1-16:0, 2-16:1) @@ -13729,6 +15376,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:73998 + - sbo: SBO:0000247 - !!omap - id: s_3093 - name: CTP @@ -13738,6 +15386,7 @@ - annotation: !!omap - chebi: CHEBI:37563 - kegg.compound: C00063 + - sbo: SBO:0000247 - !!omap - id: s_3094 - name: H+ @@ -13747,6 +15396,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_3095 - name: diphosphate @@ -13756,12 +15406,15 @@ - annotation: !!omap - chebi: CHEBI:33019 - kegg.compound: C00013 + - sbo: SBO:0000247 - !!omap - id: s_3096 - name: CDP-diacylglycerol (1-16:0, 2-16:1) - compartment: mm - formula: C44H79N3O15P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3097 - name: phosphatidate (1-16:1, 2-16:1) @@ -13770,6 +15423,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75071 + - sbo: SBO:0000247 - !!omap - id: s_3098 - name: CDP-diacylglycerol (1-16:1, 2-16:1) @@ -13778,6 +15432,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:104012 + - sbo: SBO:0000247 - !!omap - id: s_3099 - name: phosphatidate (1-18:0, 2-16:1) @@ -13786,12 +15441,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75073 + - sbo: SBO:0000247 - !!omap - id: s_3100 - name: CDP-diacylglycerol (1-18:0, 2-16:1) - compartment: mm - formula: C46H83N3O15P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3101 - name: phosphatidate (1-18:1, 2-16:1) @@ -13800,12 +15458,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75074 + - sbo: SBO:0000247 - !!omap - id: s_3102 - name: CDP-diacylglycerol (1-18:1, 2-16:1) - compartment: mm - formula: C46H81N3O15P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3103 - name: phosphatidate (1-16:0, 2-18:1) @@ -13815,6 +15476,7 @@ - annotation: !!omap - chebi: CHEBI:64844 - kegg.compound: C13889 + - sbo: SBO:0000247 - !!omap - id: s_3104 - name: CDP-diacylglycerol (1-16:0, 2-18:1) @@ -13824,18 +15486,23 @@ - annotation: !!omap - chebi: CHEBI:34077 - kegg.compound: C13892 + - sbo: SBO:0000247 - !!omap - id: s_3105 - name: phosphatidate (1-16:1, 2-18:1) - compartment: mm - formula: C37H69O8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3106 - name: CDP-diacylglycerol (1-16:1, 2-18:1) - compartment: mm - formula: C46H81N3O15P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3107 - name: L-serine @@ -13845,6 +15512,7 @@ - annotation: !!omap - chebi: CHEBI:17115 - kegg.compound: C00065 + - sbo: SBO:0000247 - !!omap - id: s_3108 - name: CMP @@ -13854,6 +15522,7 @@ - annotation: !!omap - chebi: CHEBI:60377 - kegg.compound: C00055 + - sbo: SBO:0000247 - !!omap - id: s_3109 - name: phosphatidyl-L-serine (1-16:0, 2-16:1) @@ -13862,12 +15531,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89824 + - sbo: SBO:0000247 - !!omap - id: s_3110 - name: phosphatidyl-L-serine (1-16:1, 2-16:1) - compartment: erm - formula: C38H70NO10P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3111 - name: phosphatidyl-L-serine (1-18:0, 2-16:1) @@ -13876,6 +15548,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90036 + - sbo: SBO:0000247 - !!omap - id: s_3112 - name: phosphatidyl-L-serine (1-18:1, 2-16:1) @@ -13884,6 +15557,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75101 + - sbo: SBO:0000247 - !!omap - id: s_3113 - name: phosphatidyl-L-serine (1-16:0, 2-18:1) @@ -13892,6 +15566,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134541 + - sbo: SBO:0000247 - !!omap - id: s_3114 - name: phosphatidyl-L-serine (1-16:1, 2-18:1) @@ -13900,6 +15575,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90032 + - sbo: SBO:0000247 - !!omap - id: s_3115 - name: phosphatidyl-L-serine (1-18:0, 2-18:1) @@ -13908,6 +15584,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90433 + - sbo: SBO:0000247 - !!omap - id: s_3116 - name: phosphatidyl-L-serine (1-18:1, 2-18:1) @@ -13916,6 +15593,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60568 + - sbo: SBO:0000247 - !!omap - id: s_3117 - name: myo-inositol @@ -13925,6 +15603,7 @@ - annotation: !!omap - chebi: CHEBI:17268 - kegg.compound: C00137 + - sbo: SBO:0000247 - !!omap - id: s_3118 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) @@ -13933,12 +15612,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88396 + - sbo: SBO:0000247 - !!omap - id: s_3119 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) - compartment: erm - formula: C41H75O13P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3120 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) @@ -13947,6 +15629,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88557 + - sbo: SBO:0000247 - !!omap - id: s_3121 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) @@ -13955,6 +15638,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88626 + - sbo: SBO:0000247 - !!omap - id: s_3122 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) @@ -13964,6 +15648,7 @@ - annotation: !!omap - chebi: CHEBI:73215 - kegg.compound: C13888 + - sbo: SBO:0000247 - !!omap - id: s_3123 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) @@ -13972,6 +15657,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88562 + - sbo: SBO:0000247 - !!omap - id: s_3124 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) @@ -13980,6 +15666,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77346 + - sbo: SBO:0000247 - !!omap - id: s_3125 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) @@ -13988,18 +15675,23 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88612 + - sbo: SBO:0000247 - !!omap - id: s_3126 - name: sn-2-acyl-1-lysophosphatidylinositol (16:1) - compartment: erm - formula: C25H41O12P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3127 - name: sn-2-acyl-1-lysophosphatidylinositol (18:1) - compartment: erm - formula: C27H45O12P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3128 - name: phosphatidyl-L-serine (1-16:0, 2-16:1) @@ -14008,6 +15700,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89824 + - sbo: SBO:0000247 - !!omap - id: s_3129 - name: carbon dioxide @@ -14017,6 +15710,7 @@ - annotation: !!omap - chebi: CHEBI:16526 - kegg.compound: C00011 + - sbo: SBO:0000247 - !!omap - id: s_3130 - name: phosphatidylethanolamine (1-16:0, 2-16:1) @@ -14025,12 +15719,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136147 + - sbo: SBO:0000247 - !!omap - id: s_3131 - name: phosphatidyl-L-serine (1-16:1, 2-16:1) - compartment: mm - formula: C38H70NO10P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3132 - name: phosphatidylethanolamine (1-16:1, 2-16:1) @@ -14039,6 +15736,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:138792 + - sbo: SBO:0000247 - !!omap - id: s_3133 - name: phosphatidyl-L-serine (1-18:0, 2-16:1) @@ -14047,6 +15745,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90036 + - sbo: SBO:0000247 - !!omap - id: s_3134 - name: phosphatidylethanolamine (1-18:0, 2-16:1) @@ -14055,6 +15754,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136155 + - sbo: SBO:0000247 - !!omap - id: s_3135 - name: phosphatidyl-L-serine (1-18:1, 2-16:1) @@ -14063,6 +15763,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75101 + - sbo: SBO:0000247 - !!omap - id: s_3136 - name: phosphatidylethanolamine (1-18:1, 2-16:1) @@ -14071,6 +15772,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82837 + - sbo: SBO:0000247 - !!omap - id: s_3137 - name: phosphatidyl-L-serine (1-16:0, 2-18:1) @@ -14079,6 +15781,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134541 + - sbo: SBO:0000247 - !!omap - id: s_3138 - name: phosphatidylethanolamine (1-16:0, 2-18:1) @@ -14087,6 +15790,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136148 + - sbo: SBO:0000247 - !!omap - id: s_3139 - name: phosphatidyl-L-serine (1-16:1, 2-18:1) @@ -14095,6 +15799,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90032 + - sbo: SBO:0000247 - !!omap - id: s_3140 - name: phosphatidylethanolamine (1-16:1, 2-18:1) @@ -14103,6 +15808,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90464 + - sbo: SBO:0000247 - !!omap - id: s_3141 - name: phosphatidyl-L-serine (1-18:0, 2-18:1) @@ -14111,6 +15817,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90433 + - sbo: SBO:0000247 - !!omap - id: s_3142 - name: phosphatidylethanolamine (1-18:0, 2-18:1) @@ -14119,6 +15826,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136162 + - sbo: SBO:0000247 - !!omap - id: s_3143 - name: phosphatidyl-L-serine (1-18:1, 2-18:1) @@ -14127,6 +15835,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60568 + - sbo: SBO:0000247 - !!omap - id: s_3144 - name: phosphatidylethanolamine (1-18:1, 2-18:1) @@ -14135,6 +15844,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136170 + - sbo: SBO:0000247 - !!omap - id: s_3145 - name: phosphatidyl-L-serine (1-16:0, 2-16:1) @@ -14143,6 +15853,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89824 + - sbo: SBO:0000247 - !!omap - id: s_3146 - name: H+ @@ -14152,6 +15863,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_3147 - name: carbon dioxide @@ -14161,6 +15873,7 @@ - annotation: !!omap - chebi: CHEBI:16526 - kegg.compound: C00011 + - sbo: SBO:0000247 - !!omap - id: s_3148 - name: phosphatidylethanolamine (1-16:0, 2-16:1) @@ -14169,12 +15882,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136147 + - sbo: SBO:0000247 - !!omap - id: s_3149 - name: phosphatidyl-L-serine (1-16:1, 2-16:1) - compartment: gm - formula: C38H70NO10P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3150 - name: phosphatidylethanolamine (1-16:1, 2-16:1) @@ -14183,6 +15899,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:138792 + - sbo: SBO:0000247 - !!omap - id: s_3151 - name: phosphatidyl-L-serine (1-18:0, 2-16:1) @@ -14191,6 +15908,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90036 + - sbo: SBO:0000247 - !!omap - id: s_3152 - name: phosphatidylethanolamine (1-18:0, 2-16:1) @@ -14199,6 +15917,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136155 + - sbo: SBO:0000247 - !!omap - id: s_3153 - name: phosphatidyl-L-serine (1-18:1, 2-16:1) @@ -14207,6 +15926,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75101 + - sbo: SBO:0000247 - !!omap - id: s_3154 - name: phosphatidylethanolamine (1-18:1, 2-16:1) @@ -14215,6 +15935,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82837 + - sbo: SBO:0000247 - !!omap - id: s_3155 - name: phosphatidyl-L-serine (1-16:0, 2-18:1) @@ -14223,6 +15944,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134541 + - sbo: SBO:0000247 - !!omap - id: s_3156 - name: phosphatidylethanolamine (1-16:0, 2-18:1) @@ -14231,6 +15953,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136148 + - sbo: SBO:0000247 - !!omap - id: s_3157 - name: phosphatidyl-L-serine (1-16:1, 2-18:1) @@ -14239,6 +15962,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90032 + - sbo: SBO:0000247 - !!omap - id: s_3158 - name: phosphatidylethanolamine (1-16:1, 2-18:1) @@ -14247,6 +15971,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90464 + - sbo: SBO:0000247 - !!omap - id: s_3159 - name: phosphatidyl-L-serine (1-18:0, 2-18:1) @@ -14255,6 +15980,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90433 + - sbo: SBO:0000247 - !!omap - id: s_3160 - name: phosphatidylethanolamine (1-18:0, 2-18:1) @@ -14263,6 +15989,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136162 + - sbo: SBO:0000247 - !!omap - id: s_3161 - name: phosphatidyl-L-serine (1-18:1, 2-18:1) @@ -14271,6 +15998,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60568 + - sbo: SBO:0000247 - !!omap - id: s_3162 - name: phosphatidylethanolamine (1-18:1, 2-18:1) @@ -14279,6 +16007,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136170 + - sbo: SBO:0000247 - !!omap - id: s_3163 - name: phosphatidyl-L-serine (1-16:0, 2-16:1) @@ -14287,6 +16016,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89824 + - sbo: SBO:0000247 - !!omap - id: s_3164 - name: H+ @@ -14296,6 +16026,7 @@ - annotation: !!omap - chebi: CHEBI:24636 - kegg.compound: C00080 + - sbo: SBO:0000247 - !!omap - id: s_3165 - name: carbon dioxide @@ -14305,6 +16036,7 @@ - annotation: !!omap - chebi: CHEBI:16526 - kegg.compound: C00011 + - sbo: SBO:0000247 - !!omap - id: s_3166 - name: phosphatidylethanolamine (1-16:0, 2-16:1) @@ -14313,12 +16045,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136147 + - sbo: SBO:0000247 - !!omap - id: s_3167 - name: phosphatidyl-L-serine (1-16:1, 2-16:1) - compartment: vm - formula: C38H70NO10P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3168 - name: phosphatidylethanolamine (1-16:1, 2-16:1) @@ -14327,6 +16062,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:138792 + - sbo: SBO:0000247 - !!omap - id: s_3169 - name: phosphatidyl-L-serine (1-18:0, 2-16:1) @@ -14335,6 +16071,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90036 + - sbo: SBO:0000247 - !!omap - id: s_3170 - name: phosphatidylethanolamine (1-18:0, 2-16:1) @@ -14343,6 +16080,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136155 + - sbo: SBO:0000247 - !!omap - id: s_3171 - name: phosphatidyl-L-serine (1-18:1, 2-16:1) @@ -14351,6 +16089,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75101 + - sbo: SBO:0000247 - !!omap - id: s_3172 - name: phosphatidylethanolamine (1-18:1, 2-16:1) @@ -14359,6 +16098,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82837 + - sbo: SBO:0000247 - !!omap - id: s_3173 - name: phosphatidyl-L-serine (1-16:0, 2-18:1) @@ -14367,6 +16107,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134541 + - sbo: SBO:0000247 - !!omap - id: s_3174 - name: phosphatidylethanolamine (1-16:0, 2-18:1) @@ -14375,6 +16116,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136148 + - sbo: SBO:0000247 - !!omap - id: s_3175 - name: phosphatidyl-L-serine (1-16:1, 2-18:1) @@ -14383,6 +16125,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90032 + - sbo: SBO:0000247 - !!omap - id: s_3176 - name: phosphatidylethanolamine (1-16:1, 2-18:1) @@ -14391,6 +16134,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90464 + - sbo: SBO:0000247 - !!omap - id: s_3177 - name: phosphatidyl-L-serine (1-18:0, 2-18:1) @@ -14399,6 +16143,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90433 + - sbo: SBO:0000247 - !!omap - id: s_3178 - name: phosphatidylethanolamine (1-18:0, 2-18:1) @@ -14407,6 +16152,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136162 + - sbo: SBO:0000247 - !!omap - id: s_3179 - name: phosphatidyl-L-serine (1-18:1, 2-18:1) @@ -14415,6 +16161,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60568 + - sbo: SBO:0000247 - !!omap - id: s_3180 - name: phosphatidylethanolamine (1-18:1, 2-18:1) @@ -14423,6 +16170,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136170 + - sbo: SBO:0000247 - !!omap - id: s_3181 - name: phosphatidylethanolamine (1-16:0, 2-16:1) @@ -14431,6 +16179,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136147 + - sbo: SBO:0000247 - !!omap - id: s_3182 - name: S-adenosyl-L-methionine @@ -14440,6 +16189,7 @@ - annotation: !!omap - chebi: CHEBI:15414 - kegg.compound: C00019 + - sbo: SBO:0000247 - !!omap - id: s_3183 - name: S-adenosyl-L-homocysteine @@ -14449,12 +16199,15 @@ - annotation: !!omap - chebi: CHEBI:16680 - kegg.compound: C00021 + - sbo: SBO:0000247 - !!omap - id: s_3184 - name: phosphatidyl-N-methylethanolamine (1-16:0, 2-16:1) - compartment: erm - formula: C38H74NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3185 - name: phosphatidylethanolamine (1-16:1, 2-16:1) @@ -14463,12 +16216,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:138792 + - sbo: SBO:0000247 - !!omap - id: s_3186 - name: phosphatidyl-N-methylethanolamine (1-16:1, 2-16:1) - compartment: erm - formula: C38H72NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3187 - name: phosphatidylethanolamine (1-18:0, 2-16:1) @@ -14477,12 +16233,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136155 + - sbo: SBO:0000247 - !!omap - id: s_3188 - name: phosphatidyl-N-methylethanolamine (1-18:0, 2-16:1) - compartment: erm - formula: C40H78NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3189 - name: phosphatidylethanolamine (1-18:1, 2-16:1) @@ -14491,12 +16250,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82837 + - sbo: SBO:0000247 - !!omap - id: s_3190 - name: phosphatidyl-N-methylethanolamine (1-18:1, 2-16:1) - compartment: erm - formula: C40H76NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3191 - name: phosphatidylethanolamine (1-16:0, 2-18:1) @@ -14505,12 +16267,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136148 + - sbo: SBO:0000247 - !!omap - id: s_3192 - name: phosphatidyl-N-methylethanolamine (1-16:0, 2-18:1) - compartment: erm - formula: C40H78NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3193 - name: phosphatidylethanolamine (1-16:1, 2-18:1) @@ -14519,12 +16284,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90464 + - sbo: SBO:0000247 - !!omap - id: s_3194 - name: phosphatidyl-N-methylethanolamine (1-16:1, 2-18:1) - compartment: erm - formula: C40H76NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3195 - name: phosphatidylethanolamine (1-18:0, 2-18:1) @@ -14533,12 +16301,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136162 + - sbo: SBO:0000247 - !!omap - id: s_3196 - name: phosphatidyl-N-methylethanolamine (1-18:0, 2-18:1) - compartment: erm - formula: C42H82NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3197 - name: phosphatidylethanolamine (1-18:1, 2-18:1) @@ -14547,6 +16318,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136170 + - sbo: SBO:0000247 - !!omap - id: s_3198 - name: phosphatidyl-N-methylethanolamine (1-18:1, 2-18:1) @@ -14555,48 +16327,63 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:85962 + - sbo: SBO:0000247 - !!omap - id: s_3199 - name: phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-16:1) - compartment: erm - formula: C39H76NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3200 - name: phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-16:1) - compartment: erm - formula: C39H74NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3201 - name: phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-16:1) - compartment: erm - formula: C41H80NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3202 - name: phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-16:1) - compartment: erm - formula: C41H78NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3203 - name: phosphatidyl-N,N-dimethylethanolamine (1-16:0, 2-18:1) - compartment: erm - formula: C41H80NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3204 - name: phosphatidyl-N,N-dimethylethanolamine (1-16:1, 2-18:1) - compartment: erm - formula: C41H78NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3205 - name: phosphatidyl-N,N-dimethylethanolamine (1-18:0, 2-18:1) - compartment: erm - formula: C43H84NO8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3206 - name: phosphatidyl-N,N-dimethylethanolamine (1-18:1, 2-18:1) @@ -14605,6 +16392,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:85963 + - sbo: SBO:0000247 - !!omap - id: s_3207 - name: phosphatidylcholine (1-16:0, 2-16:1) @@ -14613,6 +16401,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134592 + - sbo: SBO:0000247 - !!omap - id: s_3208 - name: phosphatidylcholine (1-16:1, 2-16:1) @@ -14621,6 +16410,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134637 + - sbo: SBO:0000247 - !!omap - id: s_3209 - name: phosphatidylcholine (1-18:0, 2-16:1) @@ -14629,6 +16419,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89972 + - sbo: SBO:0000247 - !!omap - id: s_3210 - name: phosphatidylcholine (1-18:1, 2-16:1) @@ -14637,6 +16428,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89506 + - sbo: SBO:0000247 - !!omap - id: s_3211 - name: phosphatidylcholine (1-16:0, 2-18:1) @@ -14645,6 +16437,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134594 + - sbo: SBO:0000247 - !!omap - id: s_3212 - name: phosphatidylcholine (1-16:1, 2-18:1) @@ -14653,6 +16446,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89668 + - sbo: SBO:0000247 - !!omap - id: s_3213 - name: phosphatidylcholine (1-18:0, 2-18:1) @@ -14661,6 +16455,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89679 + - sbo: SBO:0000247 - !!omap - id: s_3214 - name: phosphatidylcholine (1-18:1, 2-18:1) @@ -14669,6 +16464,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89504 + - sbo: SBO:0000247 - !!omap - id: s_3215 - name: CDP @@ -14678,6 +16474,7 @@ - annotation: !!omap - chebi: CHEBI:58069 - kegg.compound: C00112 + - sbo: SBO:0000247 - !!omap - id: s_3216 - name: CDP-ethanolamine @@ -14687,6 +16484,7 @@ - annotation: !!omap - chebi: CHEBI:57876 - kegg.compound: C00570 + - sbo: SBO:0000247 - !!omap - id: s_3217 - name: CDP-choline @@ -14696,6 +16494,7 @@ - annotation: !!omap - chebi: CHEBI:16436 - kegg.compound: C00307 + - sbo: SBO:0000247 - !!omap - id: s_3218 - name: glycerol 3-phosphate @@ -14705,6 +16504,7 @@ - annotation: !!omap - chebi: CHEBI:57597 - kegg.compound: C00093 + - sbo: SBO:0000247 - !!omap - id: s_3219 - name: CMP @@ -14714,42 +16514,55 @@ - annotation: !!omap - chebi: CHEBI:60377 - kegg.compound: C00055 + - sbo: SBO:0000247 - !!omap - id: s_3220 - name: 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-16:1) - compartment: mm - formula: C40H74O13P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3221 - name: 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-16:1) - compartment: mm - formula: C40H72O13P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3222 - name: 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:0, 2-16:1) - compartment: mm - formula: C42H76O13P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3223 - name: 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-18:1, 2-16:1) - compartment: mm - formula: C42H74O13P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3224 - name: 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:0, 2-18:1) - compartment: mm - formula: C42H76O13P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3225 - name: 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (1-16:1, 2-18:1) - compartment: mm - formula: C42H74O13P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3226 - name: H2O @@ -14759,6 +16572,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_3227 - name: phosphatidylglycerol (1-16:0, 2-16:1) @@ -14767,6 +16581,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136224 + - sbo: SBO:0000247 - !!omap - id: s_3228 - name: phosphate @@ -14776,12 +16591,15 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_3229 - name: phosphatidylglycerol (1-16:1, 2-16:1) - compartment: mm - formula: C38H71O10P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3230 - name: phosphatidylglycerol (1-18:0, 2-16:1) @@ -14790,6 +16608,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89270 + - sbo: SBO:0000247 - !!omap - id: s_3231 - name: phosphatidylglycerol (1-18:1, 2-16:1) @@ -14798,6 +16617,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89093 + - sbo: SBO:0000247 - !!omap - id: s_3232 - name: phosphatidylglycerol (1-16:0, 2-18:1) @@ -14807,6 +16627,7 @@ - annotation: !!omap - chebi: CHEBI:34080 - kegg.compound: C13833 + - sbo: SBO:0000247 - !!omap - id: s_3233 - name: phosphatidylglycerol (1-16:1, 2-18:1) @@ -14815,48 +16636,63 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89398 + - sbo: SBO:0000247 - !!omap - id: s_3234 - name: cardiolipin (1-16:0, 2-16:1, 3-16:0, 4-16:1) - compartment: mm - formula: C73H140O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3235 - name: cardiolipin (1-16:0, 2-16:1, 3-16:1, 4-16:1) - compartment: mm - formula: C73H136O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3236 - name: cardiolipin (1-16:0, 2-16:1, 3-18:0, 4-16:1) - compartment: mm - formula: C75H144O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3237 - name: cardiolipin (1-16:0, 2-16:1, 3-18:1, 4-16:1) - compartment: mm - formula: C75H140O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3238 - name: cardiolipin (1-16:0, 2-16:1, 3-16:0, 4-18:1) - compartment: mm - formula: C75H144O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3239 - name: cardiolipin (1-16:0, 2-16:1, 3-16:1, 4-18:1) - compartment: mm - formula: C75H140O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3240 - name: cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-16:1) - compartment: mm - formula: C73H138O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3241 - name: cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-16:1) @@ -14865,180 +16701,239 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:104873 + - sbo: SBO:0000247 - !!omap - id: s_3242 - name: cardiolipin (1-16:1, 2-16:1, 3-18:0, 4-16:1) - compartment: mm - formula: C75H142O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3243 - name: cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-16:1) - compartment: mm - formula: C75H138O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3244 - name: cardiolipin (1-16:1, 2-16:1, 3-16:0, 4-18:1) - compartment: mm - formula: C75H142O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3245 - name: cardiolipin (1-16:1, 2-16:1, 3-16:1, 4-18:1) - compartment: mm - formula: C75H138O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3246 - name: cardiolipin (1-18:0, 2-16:1, 3-16:0, 4-16:1) - compartment: mm - formula: C75H144O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3247 - name: cardiolipin (1-18:0, 2-16:1, 3-16:1, 4-16:1) - compartment: mm - formula: C75H140O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3248 - name: cardiolipin (1-18:0, 2-16:1, 3-18:0, 4-16:1) - compartment: mm - formula: C77H148O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3249 - name: cardiolipin (1-18:0, 2-16:1, 3-18:1, 4-16:1) - compartment: mm - formula: C77H144O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3250 - name: cardiolipin (1-18:0, 2-16:1, 3-16:0, 4-18:1) - compartment: mm - formula: C77H148O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3251 - name: cardiolipin (1-18:0, 2-16:1, 3-16:1, 4-18:1) - compartment: mm - formula: C77H144O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3252 - name: cardiolipin (1-18:1, 2-16:1, 3-16:0, 4-16:1) - compartment: mm - formula: C75H142O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3253 - name: cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-16:1) - compartment: mm - formula: C75H138O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3254 - name: cardiolipin (1-18:1, 2-16:1, 3-18:0, 4-16:1) - compartment: mm - formula: C77H146O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3255 - name: cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-16:1) - compartment: mm - formula: C77H142O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3256 - name: cardiolipin (1-18:1, 2-16:1, 3-16:0, 4-18:1) - compartment: mm - formula: C77H146O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3257 - name: cardiolipin (1-18:1, 2-16:1, 3-16:1, 4-18:1) - compartment: mm - formula: C77H142O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3258 - name: cardiolipin (1-16:0, 2-18:1, 3-16:0, 4-16:1) - compartment: mm - formula: C75H144O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3259 - name: cardiolipin (1-16:0, 2-18:1, 3-16:1, 4-16:1) - compartment: mm - formula: C75H140O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3260 - name: cardiolipin (1-16:0, 2-18:1, 3-18:0, 4-16:1) - compartment: mm - formula: C77H148O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3261 - name: cardiolipin (1-16:0, 2-18:1, 3-18:1, 4-16:1) - compartment: mm - formula: C77H144O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3262 - name: cardiolipin (1-16:0, 2-18:1, 3-16:0, 4-18:1) - compartment: mm - formula: C77H148O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3263 - name: cardiolipin (1-16:0, 2-18:1, 3-16:1, 4-18:1) - compartment: mm - formula: C77H144O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3264 - name: cardiolipin (1-16:1, 2-18:1, 3-16:0, 4-16:1) - compartment: mm - formula: C75H142O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3265 - name: cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-16:1) - compartment: mm - formula: C75H138O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3266 - name: cardiolipin (1-16:1, 2-18:1, 3-18:0, 4-16:1) - compartment: mm - formula: C77H146O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3267 - name: cardiolipin (1-16:1, 2-18:1, 3-18:1, 4-16:1) - compartment: mm - formula: C77H142O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3268 - name: cardiolipin (1-16:1, 2-18:1, 3-16:0, 4-18:1) - compartment: mm - formula: C77H146O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3269 - name: cardiolipin (1-16:1, 2-18:1, 3-16:1, 4-18:1) - compartment: mm - formula: C77H142O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3270 - name: monolysocardiolipin (2-16:1, 3-16:0, 4-16:1) - compartment: mm - formula: C57H108O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3271 - name: palmitate @@ -15048,36 +16943,47 @@ - annotation: !!omap - chebi: CHEBI:7896 - kegg.compound: C00249 + - sbo: SBO:0000247 - !!omap - id: s_3272 - name: monolysocardiolipin (2-16:1, 3-16:1, 4-16:1) - compartment: mm - formula: C57H106O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3273 - name: monolysocardiolipin (2-16:1, 3-18:0, 4-16:1) - compartment: mm - formula: C59H112O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3274 - name: monolysocardiolipin (2-16:1, 3-18:1, 4-16:1) - compartment: mm - formula: C59H110O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3275 - name: monolysocardiolipin (2-16:1, 3-16:0, 4-18:1) - compartment: mm - formula: C59H112O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3276 - name: monolysocardiolipin (2-16:1, 3-16:1, 4-18:1) - compartment: mm - formula: C59H110O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3277 - name: stearate @@ -15087,114 +16993,151 @@ - annotation: !!omap - chebi: CHEBI:25629 - kegg.compound: C01530 + - sbo: SBO:0000247 - !!omap - id: s_3278 - name: monolysocardiolipin (2-18:1, 3-16:0, 4-16:1) - compartment: mm - formula: C59H112O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3279 - name: monolysocardiolipin (2-18:1, 3-16:1, 4-16:1) - compartment: mm - formula: C59H110O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3280 - name: monolysocardiolipin (2-18:1, 3-18:0, 4-16:1) - compartment: mm - formula: C61H116O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3281 - name: monolysocardiolipin (2-18:1, 3-18:1, 4-16:1) - compartment: mm - formula: C61H114O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3282 - name: monolysocardiolipin (2-18:1, 3-16:0, 4-18:1) - compartment: mm - formula: C61H116O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3283 - name: monolysocardiolipin (2-18:1, 3-16:1, 4-18:1) - compartment: mm - formula: C61H114O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3284 - name: monolysocardiolipin (1-16:0, 2-16:1, 4-16:1) - compartment: mm - formula: C57H108O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3285 - name: monolysocardiolipin (1-16:0, 2-16:1, 4-18:1) - compartment: mm - formula: C59H112O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3286 - name: monolysocardiolipin (1-16:1, 2-16:1, 4-16:1) - compartment: mm - formula: C57H106O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3287 - name: monolysocardiolipin (1-16:1, 2-16:1, 4-18:1) - compartment: mm - formula: C59H110O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3288 - name: monolysocardiolipin (1-18:0, 2-16:1, 4-16:1) - compartment: mm - formula: C59H112O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3289 - name: monolysocardiolipin (1-18:0, 2-16:1, 4-18:1) - compartment: mm - formula: C61H116O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3290 - name: monolysocardiolipin (1-18:1, 2-16:1, 4-16:1) - compartment: mm - formula: C59H110O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3291 - name: monolysocardiolipin (1-18:1, 2-16:1, 4-18:1) - compartment: mm - formula: C61H114O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3292 - name: monolysocardiolipin (1-16:0, 2-18:1, 4-16:1) - compartment: mm - formula: C59H112O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3293 - name: monolysocardiolipin (1-16:0, 2-18:1, 4-18:1) - compartment: mm - formula: C61H116O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3294 - name: monolysocardiolipin (1-16:1, 2-18:1, 4-16:1) - compartment: mm - formula: C59H110O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3295 - name: monolysocardiolipin (1-16:1, 2-18:1, 4-18:1) - compartment: mm - formula: C61H114O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3296 - name: phosphatidylcholine (1-16:0, 2-16:1) @@ -15203,12 +17146,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134592 + - sbo: SBO:0000247 - !!omap - id: s_3297 - name: 1-acylglycerophosphocholine (16:0) - compartment: mm - formula: C24H51NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3298 - name: phosphatidylcholine (1-16:1, 2-16:1) @@ -15217,12 +17163,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134637 + - sbo: SBO:0000247 - !!omap - id: s_3299 - name: 1-acylglycerophosphocholine (16:1) - compartment: mm - formula: C24H49NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3300 - name: phosphatidylcholine (1-18:0, 2-16:1) @@ -15231,12 +17180,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89972 + - sbo: SBO:0000247 - !!omap - id: s_3301 - name: 1-acylglycerophosphocholine (18:0) - compartment: mm - formula: C26H55NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3302 - name: phosphatidylcholine (1-18:1, 2-16:1) @@ -15245,12 +17197,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89506 + - sbo: SBO:0000247 - !!omap - id: s_3303 - name: 1-acylglycerophosphocholine (18:1) - compartment: mm - formula: C26H53NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3304 - name: phosphatidylcholine (1-16:0, 2-18:1) @@ -15259,6 +17214,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134594 + - sbo: SBO:0000247 - !!omap - id: s_3305 - name: phosphatidylcholine (1-16:1, 2-18:1) @@ -15267,6 +17223,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89668 + - sbo: SBO:0000247 - !!omap - id: s_3306 - name: phosphatidylcholine (1-18:0, 2-18:1) @@ -15275,6 +17232,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89679 + - sbo: SBO:0000247 - !!omap - id: s_3307 - name: phosphatidylcholine (1-18:1, 2-18:1) @@ -15283,78 +17241,103 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89504 + - sbo: SBO:0000247 - !!omap - id: s_3308 - name: cardiolipin (1-18:1, 2-18:1, 3-16:0, 4-16:1) - compartment: mm - formula: C77H146O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3309 - name: cardiolipin (1-18:1, 2-18:1, 3-16:1, 4-16:1) - compartment: mm - formula: C77H142O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3310 - name: cardiolipin (1-18:1, 2-18:1, 3-18:0, 4-16:1) - compartment: mm - formula: C79H150O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3311 - name: cardiolipin (1-18:1, 2-18:1, 3-18:1, 4-16:1) - compartment: mm - formula: C79H146O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3312 - name: cardiolipin (1-18:1, 2-18:1, 3-16:0, 4-18:1) - compartment: mm - formula: C79H150O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3313 - name: cardiolipin (1-18:1, 2-18:1, 3-16:1, 4-18:1) - compartment: mm - formula: C79H146O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3314 - name: cardiolipin (1-16:0, 2-16:1, 3-18:1, 4-18:1) - compartment: mm - formula: C77H144O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3315 - name: cardiolipin (1-16:1, 2-16:1, 3-18:1, 4-18:1) - compartment: mm - formula: C77H142O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3316 - name: cardiolipin (1-18:0, 2-16:1, 3-18:1, 4-18:1) - compartment: mm - formula: C79H148O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3317 - name: cardiolipin (1-18:1, 2-16:1, 3-18:1, 4-18:1) - compartment: mm - formula: C79H146O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3318 - name: cardiolipin (1-16:0, 2-18:1, 3-18:1, 4-18:1) - compartment: mm - formula: C79H148O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3319 - name: cardiolipin (1-16:1, 2-18:1, 3-18:1, 4-18:1) - compartment: mm - formula: C79H146O17P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3320 - name: palmitoleoyl-CoA(4-) @@ -15364,6 +17347,7 @@ - annotation: !!omap - chebi: CHEBI:61540 - kegg.compound: C21072 + - sbo: SBO:0000247 - !!omap - id: s_3321 - name: coenzyme A @@ -15373,6 +17357,7 @@ - annotation: !!omap - chebi: CHEBI:57287 - kegg.compound: C00010 + - sbo: SBO:0000247 - !!omap - id: s_3322 - name: oleoyl-CoA @@ -15382,6 +17367,7 @@ - annotation: !!omap - chebi: CHEBI:57387 - kegg.compound: C00510 + - sbo: SBO:0000247 - !!omap - id: s_3323 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) @@ -15390,6 +17376,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88396 + - sbo: SBO:0000247 - !!omap - id: s_3324 - name: ADP @@ -15399,24 +17386,31 @@ - annotation: !!omap - chebi: CHEBI:456216 - kegg.compound: C00008 + - sbo: SBO:0000247 - !!omap - id: s_3325 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-16:1) - compartment: ce - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3326 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) - compartment: ce - formula: C41H75O13P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3327 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-16:1) - compartment: ce - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3328 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) @@ -15425,12 +17419,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88557 + - sbo: SBO:0000247 - !!omap - id: s_3329 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-16:1) - compartment: ce - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3330 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) @@ -15439,12 +17436,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88626 + - sbo: SBO:0000247 - !!omap - id: s_3331 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-16:1) - compartment: ce - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3332 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) @@ -15454,12 +17454,15 @@ - annotation: !!omap - chebi: CHEBI:73215 - kegg.compound: C13888 + - sbo: SBO:0000247 - !!omap - id: s_3333 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-18:1) - compartment: ce - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3334 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) @@ -15468,12 +17471,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88562 + - sbo: SBO:0000247 - !!omap - id: s_3335 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-18:1) - compartment: ce - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3336 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) @@ -15482,6 +17488,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77346 + - sbo: SBO:0000247 - !!omap - id: s_3337 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-18:1) @@ -15490,6 +17497,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77277 + - sbo: SBO:0000247 - !!omap - id: s_3338 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) @@ -15498,12 +17506,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88612 + - sbo: SBO:0000247 - !!omap - id: s_3339 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-18:1) - compartment: ce - formula: C45H84O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3340 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) @@ -15512,6 +17523,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88396 + - sbo: SBO:0000247 - !!omap - id: s_3341 - name: ATP @@ -15521,6 +17533,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_3342 - name: ADP @@ -15530,24 +17543,31 @@ - annotation: !!omap - chebi: CHEBI:456216 - kegg.compound: C00008 + - sbo: SBO:0000247 - !!omap - id: s_3343 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-16:1) - compartment: vm - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3344 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) - compartment: vm - formula: C41H75O13P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3345 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-16:1) - compartment: vm - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3346 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) @@ -15556,12 +17576,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88557 + - sbo: SBO:0000247 - !!omap - id: s_3347 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-16:1) - compartment: vm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3348 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) @@ -15570,12 +17593,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88626 + - sbo: SBO:0000247 - !!omap - id: s_3349 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-16:1) - compartment: vm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3350 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) @@ -15585,12 +17611,15 @@ - annotation: !!omap - chebi: CHEBI:73215 - kegg.compound: C13888 + - sbo: SBO:0000247 - !!omap - id: s_3351 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-18:1) - compartment: vm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3352 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) @@ -15599,12 +17628,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88562 + - sbo: SBO:0000247 - !!omap - id: s_3353 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-18:1) - compartment: vm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3354 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) @@ -15613,6 +17645,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77346 + - sbo: SBO:0000247 - !!omap - id: s_3355 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-18:1) @@ -15621,6 +17654,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77277 + - sbo: SBO:0000247 - !!omap - id: s_3356 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) @@ -15629,12 +17663,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88612 + - sbo: SBO:0000247 - !!omap - id: s_3357 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-18:1) - compartment: vm - formula: C45H84O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3358 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) @@ -15643,6 +17680,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88396 + - sbo: SBO:0000247 - !!omap - id: s_3359 - name: ATP @@ -15652,6 +17690,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_3360 - name: ADP @@ -15661,24 +17700,31 @@ - annotation: !!omap - chebi: CHEBI:456216 - kegg.compound: C00008 + - sbo: SBO:0000247 - !!omap - id: s_3361 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-16:1) - compartment: gm - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3362 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) - compartment: gm - formula: C41H75O13P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3363 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-16:1) - compartment: gm - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3364 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) @@ -15687,12 +17733,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88557 + - sbo: SBO:0000247 - !!omap - id: s_3365 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-16:1) - compartment: gm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3366 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) @@ -15701,12 +17750,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88626 + - sbo: SBO:0000247 - !!omap - id: s_3367 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-16:1) - compartment: gm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3368 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) @@ -15716,12 +17768,15 @@ - annotation: !!omap - chebi: CHEBI:73215 - kegg.compound: C13888 + - sbo: SBO:0000247 - !!omap - id: s_3369 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-18:1) - compartment: gm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3370 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) @@ -15730,12 +17785,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88562 + - sbo: SBO:0000247 - !!omap - id: s_3371 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-18:1) - compartment: gm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3372 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) @@ -15744,6 +17802,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77346 + - sbo: SBO:0000247 - !!omap - id: s_3373 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-18:1) @@ -15752,6 +17811,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77277 + - sbo: SBO:0000247 - !!omap - id: s_3374 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) @@ -15760,12 +17820,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88612 + - sbo: SBO:0000247 - !!omap - id: s_3375 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-18:1) - compartment: gm - formula: C45H84O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3376 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) @@ -15774,24 +17837,31 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88396 + - sbo: SBO:0000247 - !!omap - id: s_3377 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-16:1) - compartment: n - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3378 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) - compartment: n - formula: C41H75O13P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3379 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-16:1) - compartment: n - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3380 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) @@ -15800,12 +17870,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88557 + - sbo: SBO:0000247 - !!omap - id: s_3381 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-16:1) - compartment: n - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3382 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) @@ -15814,12 +17887,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88626 + - sbo: SBO:0000247 - !!omap - id: s_3383 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-16:1) - compartment: n - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3384 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) @@ -15829,12 +17905,15 @@ - annotation: !!omap - chebi: CHEBI:73215 - kegg.compound: C13888 + - sbo: SBO:0000247 - !!omap - id: s_3385 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-18:1) - compartment: n - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3386 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) @@ -15843,12 +17922,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88562 + - sbo: SBO:0000247 - !!omap - id: s_3387 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-18:1) - compartment: n - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3388 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) @@ -15857,6 +17939,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77346 + - sbo: SBO:0000247 - !!omap - id: s_3389 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-18:1) @@ -15865,6 +17948,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77277 + - sbo: SBO:0000247 - !!omap - id: s_3390 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) @@ -15873,48 +17957,63 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88612 + - sbo: SBO:0000247 - !!omap - id: s_3391 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-18:1) - compartment: n - formula: C45H84O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3392 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) - compartment: vm - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3393 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-16:1) - compartment: vm - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3394 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-16:1) - compartment: vm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3395 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-16:1) - compartment: vm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3396 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-18:1) - compartment: vm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3397 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-18:1) - compartment: vm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3398 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-18:1) @@ -15923,6 +18022,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77347 + - sbo: SBO:0000247 - !!omap - id: s_3399 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-18:1) @@ -15931,42 +18031,55 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77344 + - sbo: SBO:0000247 - !!omap - id: s_3400 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-16:1) - compartment: n - formula: C41H79O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3401 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-16:1) - compartment: n - formula: C41H77O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3402 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-16:1) - compartment: n - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3403 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-16:1) - compartment: n - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3404 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-18:1) - compartment: n - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3405 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-18:1) - compartment: n - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3406 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) @@ -15975,48 +18088,63 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77279 + - sbo: SBO:0000247 - !!omap - id: s_3407 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) - compartment: n - formula: C45H85O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3408 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-16:1) - compartment: ce - formula: C41H79O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3409 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-16:1) - compartment: ce - formula: C41H77O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3410 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-16:1) - compartment: ce - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3411 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-16:1) - compartment: ce - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3412 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-18:1) - compartment: ce - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3413 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-18:1) - compartment: ce - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3414 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) @@ -16025,60 +18153,79 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77279 + - sbo: SBO:0000247 - !!omap - id: s_3415 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) - compartment: ce - formula: C45H85O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3416 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) - compartment: vm - formula: C41H79O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3417 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) - compartment: vm - formula: C41H77O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3418 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-16:1) - compartment: vm - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3419 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-16:1) - compartment: vm - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3420 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-18:1) - compartment: vm - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3421 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-18:1) - compartment: vm - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3422 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) - compartment: vm - formula: C45H87O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3423 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) - compartment: vm - formula: C45H85O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3424 - name: 1-acylglycerophosphoethanolamine (16:0) @@ -16087,12 +18234,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90452 + - sbo: SBO:0000247 - !!omap - id: s_3425 - name: 1-acylglycerophosphoethanolamine (16:1) - compartment: erm - formula: C21H42NO7P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3426 - name: 1-acylglycerophosphoethanolamine (18:0) @@ -16101,6 +18251,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:64576 + - sbo: SBO:0000247 - !!omap - id: s_3427 - name: 1-acylglycerophosphoethanolamine (18:1) @@ -16109,30 +18260,39 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:64575 + - sbo: SBO:0000247 - !!omap - id: s_3428 - name: 1-acylglycerophosphocholine (16:0) - compartment: erm - formula: C24H51NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3429 - name: 1-acylglycerophosphocholine (16:1) - compartment: erm - formula: C24H49NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3430 - name: 1-acylglycerophosphocholine (18:0) - compartment: erm - formula: C26H55NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3431 - name: 1-acylglycerophosphocholine (18:1) - compartment: erm - formula: C26H53NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3432 - name: episterol @@ -16142,6 +18302,7 @@ - annotation: !!omap - chebi: CHEBI:23929 - kegg.compound: C15777 + - sbo: SBO:0000247 - !!omap - id: s_3433 - name: episteryl oleate @@ -16150,6 +18311,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52375 + - sbo: SBO:0000247 - !!omap - id: s_3434 - name: episteryl palmitoleate @@ -16158,6 +18320,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52376 + - sbo: SBO:0000247 - !!omap - id: s_3435 - name: fecosterol @@ -16167,6 +18330,7 @@ - annotation: !!omap - chebi: CHEBI:17038 - kegg.compound: C04525 + - sbo: SBO:0000247 - !!omap - id: s_3436 - name: fecosteryl oleate @@ -16175,6 +18339,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52379 + - sbo: SBO:0000247 - !!omap - id: s_3437 - name: fecosteryl palmitoleate @@ -16183,6 +18348,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52380 + - sbo: SBO:0000247 - !!omap - id: s_3438 - name: lanosterol @@ -16192,6 +18358,7 @@ - annotation: !!omap - chebi: CHEBI:16521 - kegg.compound: C01724 + - sbo: SBO:0000247 - !!omap - id: s_3439 - name: lanosteryl oleate @@ -16200,6 +18367,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52382 + - sbo: SBO:0000247 - !!omap - id: s_3440 - name: lanosteryl palmitoleate @@ -16208,6 +18376,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52383 + - sbo: SBO:0000247 - !!omap - id: s_3441 - name: ergosterol @@ -16217,6 +18386,7 @@ - annotation: !!omap - chebi: CHEBI:16933 - kegg.compound: C01694 + - sbo: SBO:0000247 - !!omap - id: s_3442 - name: ergosteryl oleate @@ -16225,6 +18395,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52377 + - sbo: SBO:0000247 - !!omap - id: s_3443 - name: ergosteryl palmitoleate @@ -16233,6 +18404,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52378 + - sbo: SBO:0000247 - !!omap - id: s_3444 - name: zymosterol @@ -16242,6 +18414,7 @@ - annotation: !!omap - chebi: CHEBI:18252 - kegg.compound: C05437 + - sbo: SBO:0000247 - !!omap - id: s_3445 - name: zymosteryl oleate @@ -16250,6 +18423,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52384 + - sbo: SBO:0000247 - !!omap - id: s_3446 - name: zymosteryl palmitoleate @@ -16258,6 +18432,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52385 + - sbo: SBO:0000247 - !!omap - id: s_3447 - name: sn-glycero-3-phosphocholine @@ -16267,6 +18442,7 @@ - annotation: !!omap - chebi: CHEBI:16870 - kegg.compound: C00670 + - sbo: SBO:0000247 - !!omap - id: s_3448 - name: phosphatidylcholine (1-16:0, 2-16:1) @@ -16275,6 +18451,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134592 + - sbo: SBO:0000247 - !!omap - id: s_3449 - name: H2O @@ -16284,12 +18461,15 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_3450 - name: 1-acylglycerophosphocholine (16:0) - compartment: ce - formula: C24H51NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3451 - name: palmitoleate @@ -16299,6 +18479,7 @@ - annotation: !!omap - chebi: CHEBI:32372 - kegg.compound: C08362 + - sbo: SBO:0000247 - !!omap - id: s_3452 - name: phosphatidylcholine (1-16:1, 2-16:1) @@ -16307,12 +18488,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134637 + - sbo: SBO:0000247 - !!omap - id: s_3453 - name: 1-acylglycerophosphocholine (16:1) - compartment: ce - formula: C24H49NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3454 - name: phosphatidylcholine (1-18:0, 2-16:1) @@ -16321,12 +18505,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89972 + - sbo: SBO:0000247 - !!omap - id: s_3455 - name: 1-acylglycerophosphocholine (18:0) - compartment: ce - formula: C26H55NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3456 - name: phosphatidylcholine (1-18:1, 2-16:1) @@ -16335,12 +18522,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89506 + - sbo: SBO:0000247 - !!omap - id: s_3457 - name: 1-acylglycerophosphocholine (18:1) - compartment: ce - formula: C26H53NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3458 - name: phosphatidylcholine (1-16:0, 2-18:1) @@ -16349,6 +18539,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134594 + - sbo: SBO:0000247 - !!omap - id: s_3459 - name: oleate @@ -16358,6 +18549,7 @@ - annotation: !!omap - chebi: CHEBI:30823 - kegg.compound: C00712 + - sbo: SBO:0000247 - !!omap - id: s_3460 - name: phosphatidylcholine (1-16:1, 2-18:1) @@ -16366,6 +18558,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89668 + - sbo: SBO:0000247 - !!omap - id: s_3461 - name: phosphatidylcholine (1-18:0, 2-18:1) @@ -16374,6 +18567,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89679 + - sbo: SBO:0000247 - !!omap - id: s_3462 - name: phosphatidylcholine (1-18:1, 2-18:1) @@ -16382,6 +18576,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89504 + - sbo: SBO:0000247 - !!omap - id: s_3463 - name: palmitate @@ -16391,6 +18586,7 @@ - annotation: !!omap - chebi: CHEBI:7896 - kegg.compound: C00249 + - sbo: SBO:0000247 - !!omap - id: s_3464 - name: stearate @@ -16400,6 +18596,7 @@ - annotation: !!omap - chebi: CHEBI:25629 - kegg.compound: C01530 + - sbo: SBO:0000247 - !!omap - id: s_3465 - name: phosphatidylethanolamine (1-16:0, 2-16:1) @@ -16408,6 +18605,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136147 + - sbo: SBO:0000247 - !!omap - id: s_3466 - name: 1-acylglycerophosphoethanolamine (16:0) @@ -16416,6 +18614,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90452 + - sbo: SBO:0000247 - !!omap - id: s_3467 - name: phosphatidylethanolamine (1-16:1, 2-16:1) @@ -16424,12 +18623,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:138792 + - sbo: SBO:0000247 - !!omap - id: s_3468 - name: 1-acylglycerophosphoethanolamine (16:1) - compartment: ce - formula: C21H42NO7P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3469 - name: phosphatidylethanolamine (1-18:0, 2-16:1) @@ -16438,6 +18640,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136155 + - sbo: SBO:0000247 - !!omap - id: s_3470 - name: 1-acylglycerophosphoethanolamine (18:0) @@ -16446,6 +18649,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:64576 + - sbo: SBO:0000247 - !!omap - id: s_3471 - name: phosphatidylethanolamine (1-18:1, 2-16:1) @@ -16454,6 +18658,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82837 + - sbo: SBO:0000247 - !!omap - id: s_3472 - name: 1-acylglycerophosphoethanolamine (18:1) @@ -16462,6 +18667,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:64575 + - sbo: SBO:0000247 - !!omap - id: s_3473 - name: phosphatidylethanolamine (1-16:0, 2-18:1) @@ -16470,6 +18676,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136148 + - sbo: SBO:0000247 - !!omap - id: s_3474 - name: phosphatidylethanolamine (1-16:1, 2-18:1) @@ -16478,6 +18685,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90464 + - sbo: SBO:0000247 - !!omap - id: s_3475 - name: phosphatidylethanolamine (1-18:0, 2-18:1) @@ -16486,6 +18694,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136162 + - sbo: SBO:0000247 - !!omap - id: s_3476 - name: phosphatidylethanolamine (1-18:1, 2-18:1) @@ -16494,6 +18703,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136170 + - sbo: SBO:0000247 - !!omap - id: s_3477 - name: sn-glycero-3-phosphoethanolamine @@ -16503,6 +18713,7 @@ - annotation: !!omap - chebi: CHEBI:16929 - kegg.compound: C01233 + - sbo: SBO:0000247 - !!omap - id: s_3478 - name: phosphatidyl-L-serine (1-16:0, 2-16:1) @@ -16511,22 +18722,29 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89824 + - sbo: SBO:0000247 - !!omap - id: s_3479 - name: 1-acylglycerophosphoserine (16:0) - compartment: ce - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3480 - name: phosphatidyl-L-serine (1-16:1, 2-16:1) - compartment: ce - formula: C38H70NO10P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3481 - name: 1-acylglycerophosphoserine (16:1) - compartment: ce - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3482 - name: phosphatidyl-L-serine (1-18:0, 2-16:1) @@ -16535,11 +18753,14 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90036 + - sbo: SBO:0000247 - !!omap - id: s_3483 - name: 1-acylglycerophosphoserine (18:0) - compartment: ce - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3484 - name: phosphatidyl-L-serine (1-18:1, 2-16:1) @@ -16548,11 +18769,14 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75101 + - sbo: SBO:0000247 - !!omap - id: s_3485 - name: 1-acylglycerophosphoserine (18:1) - compartment: ce - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3486 - name: phosphatidyl-L-serine (1-16:0, 2-18:1) @@ -16561,6 +18785,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134541 + - sbo: SBO:0000247 - !!omap - id: s_3487 - name: phosphatidyl-L-serine (1-16:1, 2-18:1) @@ -16569,6 +18794,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90032 + - sbo: SBO:0000247 - !!omap - id: s_3488 - name: phosphatidyl-L-serine (1-18:0, 2-18:1) @@ -16577,6 +18803,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90433 + - sbo: SBO:0000247 - !!omap - id: s_3489 - name: phosphatidyl-L-serine (1-18:1, 2-18:1) @@ -16585,6 +18812,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:60568 + - sbo: SBO:0000247 - !!omap - id: s_3490 - name: sn-glycero-3-phosphoserine @@ -16593,6 +18821,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:64945 + - sbo: SBO:0000247 - !!omap - id: s_3491 - name: 1-acylglycerophosphoinositol (16:0) @@ -16601,6 +18830,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73218 + - sbo: SBO:0000247 - !!omap - id: s_3492 - name: 1-acylglycerophosphoinositol (16:1) @@ -16609,6 +18839,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:138108 + - sbo: SBO:0000247 - !!omap - id: s_3493 - name: 1-acylglycerophosphoinositol (18:0) @@ -16617,6 +18848,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:83054 + - sbo: SBO:0000247 - !!omap - id: s_3494 - name: 1-acylglycerophosphoinositol (18:1) @@ -16625,6 +18857,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82753 + - sbo: SBO:0000247 - !!omap - id: s_3495 - name: 1-(sn-glycero-3-phospho)-1D-myo-inositol @@ -16634,12 +18867,15 @@ - annotation: !!omap - chebi: CHEBI:58444 - kegg.compound: C01225 + - sbo: SBO:0000247 - !!omap - id: s_3496 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-16:1) - compartment: c - formula: C41H79O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3497 - name: diglyceride (1-16:0, 2-16:1) @@ -16648,6 +18884,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82929 + - sbo: SBO:0000247 - !!omap - id: s_3498 - name: 1D-myo-inositol 1,4,5-trisphosphate @@ -16657,12 +18894,15 @@ - annotation: !!omap - chebi: CHEBI:203600 - kegg.compound: C01245 + - sbo: SBO:0000247 - !!omap - id: s_3499 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-16:1) - compartment: c - formula: C41H77O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3500 - name: diglyceride (1-16:1, 2-16:1) @@ -16671,12 +18911,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:84417 + - sbo: SBO:0000247 - !!omap - id: s_3501 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-16:1) - compartment: c - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3502 - name: diglyceride (1-18:0, 2-16:1) @@ -16685,12 +18928,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88527 + - sbo: SBO:0000247 - !!omap - id: s_3503 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-16:1) - compartment: c - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3504 - name: diglyceride (1-18:1, 2-16:1) @@ -16699,12 +18945,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89229 + - sbo: SBO:0000247 - !!omap - id: s_3505 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-18:1) - compartment: c - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3506 - name: diglyceride (1-16:0, 2-18:1) @@ -16713,12 +18962,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88454 + - sbo: SBO:0000247 - !!omap - id: s_3507 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-18:1) - compartment: c - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3508 - name: diglyceride (1-16:1, 2-18:1) @@ -16727,6 +18979,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88500 + - sbo: SBO:0000247 - !!omap - id: s_3509 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) @@ -16735,6 +18988,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77279 + - sbo: SBO:0000247 - !!omap - id: s_3510 - name: diglyceride (1-18:0, 2-18:1) @@ -16743,12 +18997,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75468 + - sbo: SBO:0000247 - !!omap - id: s_3511 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) - compartment: c - formula: C45H85O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3512 - name: diglyceride (1-18:1, 2-18:1) @@ -16757,6 +19014,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52333 + - sbo: SBO:0000247 - !!omap - id: s_3513 - name: diglyceride (1-16:0, 2-16:1) @@ -16765,6 +19023,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82929 + - sbo: SBO:0000247 - !!omap - id: s_3514 - name: diglyceride (1-16:1, 2-16:1) @@ -16773,6 +19032,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:84417 + - sbo: SBO:0000247 - !!omap - id: s_3515 - name: diglyceride (1-18:0, 2-16:1) @@ -16781,6 +19041,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88527 + - sbo: SBO:0000247 - !!omap - id: s_3516 - name: diglyceride (1-18:1, 2-16:1) @@ -16789,6 +19050,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89229 + - sbo: SBO:0000247 - !!omap - id: s_3517 - name: diglyceride (1-16:0, 2-18:1) @@ -16797,6 +19059,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88454 + - sbo: SBO:0000247 - !!omap - id: s_3518 - name: diglyceride (1-16:1, 2-18:1) @@ -16805,6 +19068,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88500 + - sbo: SBO:0000247 - !!omap - id: s_3519 - name: diglyceride (1-18:0, 2-18:1) @@ -16813,6 +19077,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75468 + - sbo: SBO:0000247 - !!omap - id: s_3520 - name: diglyceride (1-18:1, 2-18:1) @@ -16821,6 +19086,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52333 + - sbo: SBO:0000247 - !!omap - id: s_3521 - name: diglyceride (1-16:0, 2-16:1) @@ -16829,6 +19095,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82929 + - sbo: SBO:0000247 - !!omap - id: s_3522 - name: diglyceride (1-16:1, 2-16:1) @@ -16837,6 +19104,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:84417 + - sbo: SBO:0000247 - !!omap - id: s_3523 - name: diglyceride (1-18:0, 2-16:1) @@ -16845,6 +19113,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88527 + - sbo: SBO:0000247 - !!omap - id: s_3524 - name: diglyceride (1-18:1, 2-16:1) @@ -16853,6 +19122,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89229 + - sbo: SBO:0000247 - !!omap - id: s_3525 - name: diglyceride (1-16:0, 2-18:1) @@ -16861,6 +19131,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88454 + - sbo: SBO:0000247 - !!omap - id: s_3526 - name: diglyceride (1-16:1, 2-18:1) @@ -16869,6 +19140,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88500 + - sbo: SBO:0000247 - !!omap - id: s_3527 - name: phosphatidate (1-16:0, 2-16:1) @@ -16877,6 +19149,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:73998 + - sbo: SBO:0000247 - !!omap - id: s_3528 - name: phosphatidate (1-16:1, 2-16:1) @@ -16885,6 +19158,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75071 + - sbo: SBO:0000247 - !!omap - id: s_3529 - name: phosphatidate (1-18:0, 2-16:1) @@ -16893,6 +19167,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75073 + - sbo: SBO:0000247 - !!omap - id: s_3530 - name: phosphatidate (1-18:1, 2-16:1) @@ -16901,6 +19176,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75074 + - sbo: SBO:0000247 - !!omap - id: s_3531 - name: phosphatidate (1-16:0, 2-18:1) @@ -16910,12 +19186,15 @@ - annotation: !!omap - chebi: CHEBI:64844 - kegg.compound: C13889 + - sbo: SBO:0000247 - !!omap - id: s_3532 - name: phosphatidate (1-16:1, 2-18:1) - compartment: ce - formula: C37H69O8P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3533 - name: phosphatidate (1-18:0, 2-18:1) @@ -16924,6 +19203,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74847 + - sbo: SBO:0000247 - !!omap - id: s_3534 - name: phosphatidate (1-18:1, 2-18:1) @@ -16932,12 +19212,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:83775 + - sbo: SBO:0000247 - !!omap - id: s_3535 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) - compartment: ce - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3536 - name: phosphate @@ -16947,36 +19230,47 @@ - annotation: !!omap - chebi: CHEBI:43474 - kegg.compound: C00009 + - sbo: SBO:0000247 - !!omap - id: s_3537 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-16:1) - compartment: ce - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3538 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-16:1) - compartment: ce - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3539 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-16:1) - compartment: ce - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3540 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-18:1) - compartment: ce - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3541 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-18:1) - compartment: ce - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3542 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-18:1) @@ -16985,6 +19279,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77347 + - sbo: SBO:0000247 - !!omap - id: s_3543 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-18:1) @@ -16993,12 +19288,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77344 + - sbo: SBO:0000247 - !!omap - id: s_3544 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) - compartment: c - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3545 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-16:1) @@ -17007,24 +19305,31 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88396 + - sbo: SBO:0000247 - !!omap - id: s_3546 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-16:1) - compartment: c - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3547 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-16:1) - compartment: c - formula: C41H75O13P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3548 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-16:1) - compartment: c - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3549 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-16:1) @@ -17033,12 +19338,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88557 + - sbo: SBO:0000247 - !!omap - id: s_3550 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-16:1) - compartment: c - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3551 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-16:1) @@ -17047,12 +19355,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88626 + - sbo: SBO:0000247 - !!omap - id: s_3552 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-18:1) - compartment: c - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3553 - name: 1-phosphatidyl-1D-myo-inositol (1-16:0, 2-18:1) @@ -17062,12 +19373,15 @@ - annotation: !!omap - chebi: CHEBI:73215 - kegg.compound: C13888 + - sbo: SBO:0000247 - !!omap - id: s_3554 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-18:1) - compartment: c - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3555 - name: 1-phosphatidyl-1D-myo-inositol (1-16:1, 2-18:1) @@ -17076,6 +19390,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88562 + - sbo: SBO:0000247 - !!omap - id: s_3556 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-18:1) @@ -17084,6 +19399,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77347 + - sbo: SBO:0000247 - !!omap - id: s_3557 - name: 1-phosphatidyl-1D-myo-inositol (1-18:0, 2-18:1) @@ -17092,6 +19408,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77346 + - sbo: SBO:0000247 - !!omap - id: s_3558 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-18:1) @@ -17100,6 +19417,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77344 + - sbo: SBO:0000247 - !!omap - id: s_3559 - name: 1-phosphatidyl-1D-myo-inositol (1-18:1, 2-18:1) @@ -17108,42 +19426,55 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88612 + - sbo: SBO:0000247 - !!omap - id: s_3560 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) - compartment: erm - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3561 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-16:1) - compartment: erm - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3562 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-16:1) - compartment: erm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3563 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-16:1) - compartment: erm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3564 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-18:1) - compartment: erm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3565 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-18:1) - compartment: erm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3566 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-18:1) @@ -17152,6 +19483,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77347 + - sbo: SBO:0000247 - !!omap - id: s_3567 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-18:1) @@ -17160,42 +19492,55 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77344 + - sbo: SBO:0000247 - !!omap - id: s_3568 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-16:1) - compartment: gm - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3569 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-16:1) - compartment: gm - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3570 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-16:1) - compartment: gm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3571 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-16:1) - compartment: gm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3572 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:0, 2-18:1) - compartment: gm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3573 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-16:1, 2-18:1) - compartment: gm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3574 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:0, 2-18:1) @@ -17204,6 +19549,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77347 + - sbo: SBO:0000247 - !!omap - id: s_3575 - name: 1-phosphatidyl-1D-myo-inositol 3-phosphate (1-18:1, 2-18:1) @@ -17212,42 +19558,55 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77344 + - sbo: SBO:0000247 - !!omap - id: s_3576 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-16:1) - compartment: c - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3577 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-16:1) - compartment: c - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3578 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-16:1) - compartment: c - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3579 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-16:1) - compartment: c - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3580 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-18:1) - compartment: c - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3581 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-18:1) - compartment: c - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3582 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-18:1) @@ -17256,48 +19615,63 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77277 + - sbo: SBO:0000247 - !!omap - id: s_3583 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-18:1) - compartment: c - formula: C45H84O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3584 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-16:1) - compartment: erm - formula: C41H78O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3585 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-16:1) - compartment: erm - formula: C41H76O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3586 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-16:1) - compartment: erm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3587 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-16:1) - compartment: erm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3588 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:0, 2-18:1) - compartment: erm - formula: C43H82O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3589 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-16:1, 2-18:1) - compartment: erm - formula: C43H80O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3590 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:0, 2-18:1) @@ -17306,144 +19680,191 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77277 + - sbo: SBO:0000247 - !!omap - id: s_3591 - name: 1-phosphatidyl-1D-myo-inositol 4-phosphate (1-18:1, 2-18:1) - compartment: erm - formula: C45H84O16P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3592 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) - compartment: ce - formula: C41H79O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3593 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) - compartment: ce - formula: C41H77O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3594 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-16:1) - compartment: ce - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3595 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-16:1) - compartment: ce - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3596 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-18:1) - compartment: ce - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3597 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-18:1) - compartment: ce - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3598 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) - compartment: ce - formula: C45H87O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3599 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) - compartment: ce - formula: C45H85O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3600 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-16:1) - compartment: c - formula: C41H79O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3601 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-16:1) - compartment: c - formula: C41H77O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3602 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-16:1) - compartment: c - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3603 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-16:1) - compartment: c - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3604 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:0, 2-18:1) - compartment: c - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3605 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-16:1, 2-18:1) - compartment: c - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3606 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:0, 2-18:1) - compartment: c - formula: C45H87O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3607 - name: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate (1-18:1, 2-18:1) - compartment: c - formula: C45H85O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3608 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-16:1) - compartment: erm - formula: C41H79O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3609 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-16:1) - compartment: erm - formula: C41H77O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3610 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-16:1) - compartment: erm - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3611 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-16:1) - compartment: erm - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3612 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:0, 2-18:1) - compartment: erm - formula: C43H83O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3613 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-16:1, 2-18:1) - compartment: erm - formula: C43H81O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3614 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:0, 2-18:1) @@ -17452,36 +19873,47 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:77279 + - sbo: SBO:0000247 - !!omap - id: s_3615 - name: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate (1-18:1, 2-18:1) - compartment: erm - formula: C45H85O19P3 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3616 - name: 1,2-diacylglycerol 3-diphosphate (1-16:0, 2-16:1) - compartment: vm - formula: C35H68O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3617 - name: 1,2-diacylglycerol 3-diphosphate (1-16:1, 2-16:1) - compartment: vm - formula: C35H66O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3618 - name: 1,2-diacylglycerol 3-diphosphate (1-18:0, 2-16:1) - compartment: vm - formula: C37H72O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3619 - name: 1,2-diacylglycerol 3-diphosphate (1-18:1, 2-16:1) - compartment: vm - formula: C37H70O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3620 - name: 1,2-diacylglycerol 3-diphosphate (1-16:0, 2-18:1) @@ -17491,48 +19923,63 @@ - annotation: !!omap - chebi: CHEBI:34087 - kegg.compound: C13890 + - sbo: SBO:0000247 - !!omap - id: s_3621 - name: 1,2-diacylglycerol 3-diphosphate (1-16:1, 2-18:1) - compartment: vm - formula: C37H70O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3622 - name: 1,2-diacylglycerol 3-diphosphate (1-18:0, 2-18:1) - compartment: vm - formula: C39H76O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3623 - name: 1,2-diacylglycerol 3-diphosphate (1-18:1, 2-18:1) - compartment: vm - formula: C39H74O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3624 - name: 1,2-diacylglycerol 3-diphosphate (1-16:0, 2-16:1) - compartment: gm - formula: C35H68O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3625 - name: 1,2-diacylglycerol 3-diphosphate (1-16:1, 2-16:1) - compartment: gm - formula: C35H66O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3626 - name: 1,2-diacylglycerol 3-diphosphate (1-18:0, 2-16:1) - compartment: gm - formula: C37H72O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3627 - name: 1,2-diacylglycerol 3-diphosphate (1-18:1, 2-16:1) - compartment: gm - formula: C37H70O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3628 - name: 1,2-diacylglycerol 3-diphosphate (1-16:0, 2-18:1) @@ -17542,24 +19989,31 @@ - annotation: !!omap - chebi: CHEBI:34087 - kegg.compound: C13890 + - sbo: SBO:0000247 - !!omap - id: s_3629 - name: 1,2-diacylglycerol 3-diphosphate (1-16:1, 2-18:1) - compartment: gm - formula: C37H70O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3630 - name: 1,2-diacylglycerol 3-diphosphate (1-18:0, 2-18:1) - compartment: gm - formula: C39H76O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3631 - name: 1,2-diacylglycerol 3-diphosphate (1-18:1, 2-18:1) - compartment: gm - formula: C39H74O11P2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3632 - name: 1-acyl-sn-glycerol 3-phosphate (16:0) @@ -17569,6 +20023,7 @@ - annotation: !!omap - chebi: CHEBI:15799 - kegg.compound: C04036 + - sbo: SBO:0000247 - !!omap - id: s_3633 - name: 1-monoglyceride (16:0) @@ -17577,6 +20032,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134127 + - sbo: SBO:0000247 - !!omap - id: s_3634 - name: 1-acyl-sn-glycerol 3-phosphate (16:1) @@ -17585,6 +20041,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75070 + - sbo: SBO:0000247 - !!omap - id: s_3635 - name: 1-monoglyceride (16:1) @@ -17593,6 +20050,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134128 + - sbo: SBO:0000247 - !!omap - id: s_3636 - name: 1-acyl-sn-glycerol 3-phosphate (18:0) @@ -17601,6 +20059,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74850 + - sbo: SBO:0000247 - !!omap - id: s_3637 - name: 1-monoglyceride (18:0) @@ -17609,6 +20068,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134129 + - sbo: SBO:0000247 - !!omap - id: s_3638 - name: 1-acyl-sn-glycerol 3-phosphate (18:1) @@ -17617,6 +20077,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62837 + - sbo: SBO:0000247 - !!omap - id: s_3639 - name: 1-monoglyceride (18:1) @@ -17625,6 +20086,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134130 + - sbo: SBO:0000247 - !!omap - id: s_3640 - name: 1-acyl-sn-glycerol 3-phosphate (16:0) @@ -17634,6 +20096,7 @@ - annotation: !!omap - chebi: CHEBI:15799 - kegg.compound: C04036 + - sbo: SBO:0000247 - !!omap - id: s_3641 - name: 1-monoglyceride (16:0) @@ -17642,6 +20105,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134127 + - sbo: SBO:0000247 - !!omap - id: s_3642 - name: 1-acyl-sn-glycerol 3-phosphate (16:1) @@ -17650,6 +20114,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75070 + - sbo: SBO:0000247 - !!omap - id: s_3643 - name: 1-monoglyceride (16:1) @@ -17658,6 +20123,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134128 + - sbo: SBO:0000247 - !!omap - id: s_3644 - name: 1-acyl-sn-glycerol 3-phosphate (18:0) @@ -17666,6 +20132,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74850 + - sbo: SBO:0000247 - !!omap - id: s_3645 - name: 1-monoglyceride (18:0) @@ -17674,6 +20141,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134129 + - sbo: SBO:0000247 - !!omap - id: s_3646 - name: 1-acyl-sn-glycerol 3-phosphate (18:1) @@ -17682,6 +20150,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62837 + - sbo: SBO:0000247 - !!omap - id: s_3647 - name: 1-monoglyceride (18:1) @@ -17690,6 +20159,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134130 + - sbo: SBO:0000247 - !!omap - id: s_3648 - name: 1-acyl-sn-glycerol 3-phosphate (16:0) @@ -17699,6 +20169,7 @@ - annotation: !!omap - chebi: CHEBI:15799 - kegg.compound: C04036 + - sbo: SBO:0000247 - !!omap - id: s_3649 - name: 1-monoglyceride (16:0) @@ -17707,6 +20178,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134127 + - sbo: SBO:0000247 - !!omap - id: s_3650 - name: 1-acyl-sn-glycerol 3-phosphate (16:1) @@ -17715,6 +20187,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75070 + - sbo: SBO:0000247 - !!omap - id: s_3651 - name: 1-monoglyceride (16:1) @@ -17723,6 +20196,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134128 + - sbo: SBO:0000247 - !!omap - id: s_3652 - name: 1-acyl-sn-glycerol 3-phosphate (18:0) @@ -17731,6 +20205,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:74850 + - sbo: SBO:0000247 - !!omap - id: s_3653 - name: 1-monoglyceride (18:0) @@ -17739,6 +20214,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134129 + - sbo: SBO:0000247 - !!omap - id: s_3654 - name: 1-acyl-sn-glycerol 3-phosphate (18:1) @@ -17747,6 +20223,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:62837 + - sbo: SBO:0000247 - !!omap - id: s_3655 - name: 1-monoglyceride (18:1) @@ -17755,6 +20232,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134130 + - sbo: SBO:0000247 - !!omap - id: s_3656 - name: ergosteryl palmitoleate @@ -17763,6 +20241,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52378 + - sbo: SBO:0000247 - !!omap - id: s_3657 - name: H2O @@ -17772,6 +20251,7 @@ - annotation: !!omap - chebi: CHEBI:15377 - kegg.compound: C00001 + - sbo: SBO:0000247 - !!omap - id: s_3658 - name: ergosteryl oleate @@ -17780,6 +20260,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52377 + - sbo: SBO:0000247 - !!omap - id: s_3659 - name: episteryl palmitoleate @@ -17788,6 +20269,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52376 + - sbo: SBO:0000247 - !!omap - id: s_3660 - name: episterol @@ -17797,6 +20279,7 @@ - annotation: !!omap - chebi: CHEBI:23929 - kegg.compound: C15777 + - sbo: SBO:0000247 - !!omap - id: s_3661 - name: episteryl oleate @@ -17805,6 +20288,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52375 + - sbo: SBO:0000247 - !!omap - id: s_3662 - name: fecosteryl palmitoleate @@ -17813,6 +20297,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52380 + - sbo: SBO:0000247 - !!omap - id: s_3663 - name: fecosteryl oleate @@ -17821,6 +20306,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52379 + - sbo: SBO:0000247 - !!omap - id: s_3664 - name: lanosteryl palmitoleate @@ -17829,6 +20315,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52383 + - sbo: SBO:0000247 - !!omap - id: s_3665 - name: lanosterol @@ -17838,6 +20325,7 @@ - annotation: !!omap - chebi: CHEBI:16521 - kegg.compound: C01724 + - sbo: SBO:0000247 - !!omap - id: s_3666 - name: lanosteryl oleate @@ -17846,6 +20334,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52382 + - sbo: SBO:0000247 - !!omap - id: s_3667 - name: zymosteryl palmitoleate @@ -17854,6 +20343,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52385 + - sbo: SBO:0000247 - !!omap - id: s_3668 - name: zymosteryl oleate @@ -17862,6 +20352,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52384 + - sbo: SBO:0000247 - !!omap - id: s_3669 - name: zymosteryl palmitoleate @@ -17870,6 +20361,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52385 + - sbo: SBO:0000247 - !!omap - id: s_3670 - name: zymosteryl oleate @@ -17878,6 +20370,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52384 + - sbo: SBO:0000247 - !!omap - id: s_3671 - name: 1-monoglyceride (16:0) @@ -17886,6 +20379,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134127 + - sbo: SBO:0000247 - !!omap - id: s_3672 - name: 1-monoglyceride (16:1) @@ -17894,6 +20388,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134128 + - sbo: SBO:0000247 - !!omap - id: s_3673 - name: 1-monoglyceride (18:0) @@ -17902,6 +20397,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134129 + - sbo: SBO:0000247 - !!omap - id: s_3674 - name: 1-monoglyceride (18:1) @@ -17910,6 +20406,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134130 + - sbo: SBO:0000247 - !!omap - id: s_3675 - name: diglyceride (1-16:0, 2-18:1) @@ -17918,6 +20415,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88454 + - sbo: SBO:0000247 - !!omap - id: s_3676 - name: 1-monoglyceride (16:0) @@ -17926,6 +20424,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134127 + - sbo: SBO:0000247 - !!omap - id: s_3677 - name: oleate @@ -17935,6 +20434,7 @@ - annotation: !!omap - chebi: CHEBI:30823 - kegg.compound: C00712 + - sbo: SBO:0000247 - !!omap - id: s_3678 - name: diglyceride (1-16:1, 2-18:1) @@ -17943,6 +20443,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:88500 + - sbo: SBO:0000247 - !!omap - id: s_3679 - name: 1-monoglyceride (16:1) @@ -17951,6 +20452,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134128 + - sbo: SBO:0000247 - !!omap - id: s_3680 - name: diglyceride (1-18:0, 2-18:1) @@ -17959,6 +20461,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75468 + - sbo: SBO:0000247 - !!omap - id: s_3681 - name: 1-monoglyceride (18:0) @@ -17967,6 +20470,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134129 + - sbo: SBO:0000247 - !!omap - id: s_3682 - name: diglyceride (1-18:1, 2-18:1) @@ -17975,6 +20479,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:52333 + - sbo: SBO:0000247 - !!omap - id: s_3683 - name: 1-monoglyceride (18:1) @@ -17983,6 +20488,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134130 + - sbo: SBO:0000247 - !!omap - id: s_3684 - name: glycerol @@ -17992,6 +20498,7 @@ - annotation: !!omap - chebi: CHEBI:17754 - kegg.compound: C00116 + - sbo: SBO:0000247 - !!omap - id: s_3685 - name: 1-acylglycerophosphoethanolamine (16:0) @@ -18000,6 +20507,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90452 + - sbo: SBO:0000247 - !!omap - id: s_3686 - name: phosphatidylethanolamine (1-16:0, 2-18:1) @@ -18008,12 +20516,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136148 + - sbo: SBO:0000247 - !!omap - id: s_3687 - name: 1-acylglycerophosphoethanolamine (16:1) - compartment: lp - formula: C21H42NO7P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3688 - name: phosphatidylethanolamine (1-16:1, 2-18:1) @@ -18022,6 +20533,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:90464 + - sbo: SBO:0000247 - !!omap - id: s_3689 - name: 1-acylglycerophosphoethanolamine (18:0) @@ -18030,6 +20542,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:64576 + - sbo: SBO:0000247 - !!omap - id: s_3690 - name: phosphatidylethanolamine (1-18:0, 2-18:1) @@ -18038,6 +20551,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136162 + - sbo: SBO:0000247 - !!omap - id: s_3691 - name: 1-acylglycerophosphoethanolamine (18:1) @@ -18046,6 +20560,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:64575 + - sbo: SBO:0000247 - !!omap - id: s_3692 - name: phosphatidylethanolamine (1-18:1, 2-18:1) @@ -18054,6 +20569,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136170 + - sbo: SBO:0000247 - !!omap - id: s_3693 - name: phosphatidylcholine (1-16:0, 2-16:1) @@ -18062,12 +20578,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134592 + - sbo: SBO:0000247 - !!omap - id: s_3694 - name: 1-acylglycerophosphocholine (16:0) - compartment: lp - formula: C24H51NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3695 - name: phosphatidylcholine (1-16:1, 2-16:1) @@ -18076,12 +20595,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134637 + - sbo: SBO:0000247 - !!omap - id: s_3696 - name: 1-acylglycerophosphocholine (16:1) - compartment: lp - formula: C24H49NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3697 - name: phosphatidylcholine (1-18:0, 2-16:1) @@ -18090,12 +20612,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89972 + - sbo: SBO:0000247 - !!omap - id: s_3698 - name: 1-acylglycerophosphocholine (18:0) - compartment: lp - formula: C26H55NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3699 - name: phosphatidylcholine (1-18:1, 2-16:1) @@ -18104,12 +20629,15 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89506 + - sbo: SBO:0000247 - !!omap - id: s_3700 - name: 1-acylglycerophosphocholine (18:1) - compartment: lp - formula: C26H53NO7P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3701 - name: phosphatidylcholine (1-16:0, 2-18:1) @@ -18118,6 +20646,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:134594 + - sbo: SBO:0000247 - !!omap - id: s_3702 - name: phosphatidylcholine (1-16:1, 2-18:1) @@ -18126,6 +20655,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89668 + - sbo: SBO:0000247 - !!omap - id: s_3703 - name: phosphatidylcholine (1-18:0, 2-18:1) @@ -18134,6 +20664,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89679 + - sbo: SBO:0000247 - !!omap - id: s_3704 - name: phosphatidylcholine (1-18:1, 2-18:1) @@ -18142,6 +20673,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:89504 + - sbo: SBO:0000247 - !!omap - id: s_3705 - name: phosphatidylethanolamine (1-16:0, 2-16:1) @@ -18150,6 +20682,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136147 + - sbo: SBO:0000247 - !!omap - id: s_3706 - name: phosphatidylethanolamine (1-16:1, 2-16:1) @@ -18158,6 +20691,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:138792 + - sbo: SBO:0000247 - !!omap - id: s_3707 - name: phosphatidylethanolamine (1-18:0, 2-16:1) @@ -18166,6 +20700,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:136155 + - sbo: SBO:0000247 - !!omap - id: s_3708 - name: phosphatidylethanolamine (1-18:1, 2-16:1) @@ -18174,36 +20709,47 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:82837 + - sbo: SBO:0000247 - !!omap - id: s_3709 - name: ergosterol ester backbone - compartment: erm - formula: C28H42 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3710 - name: phosphatidyl-L-serine backbone - compartment: erm - formula: C6H10NO6P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3711 - name: phosphatidylcholine backbone - compartment: erm - formula: C8H16NO3P - charge: 1 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3712 - name: phosphatidylethanolamine backbone - compartment: erm - formula: C5H10NO4P - charge: 0 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3713 - name: triglyceride backbone - compartment: erm - formula: C3H2 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3714 - name: heme a @@ -18213,6 +20759,7 @@ - annotation: !!omap - chebi: CHEBI:24479 - kegg.compound: C15670 + - sbo: SBO:0000247 - !!omap - id: s_3715 - name: raffinose @@ -18222,6 +20769,7 @@ - annotation: !!omap - chebi: CHEBI:16634 - kegg.compound: C00492 + - sbo: SBO:0000247 - !!omap - id: s_3716 - name: melibiose @@ -18231,155 +20779,218 @@ - annotation: !!omap - chebi: CHEBI:28053 - kegg.compound: C05402 + - sbo: SBO:0000247 - !!omap - id: s_3717 - name: protein - compartment: c + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3718 - name: carbohydrate - compartment: c + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3719 - name: RNA - compartment: c + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3720 - name: DNA - compartment: c + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3721 - name: ceramide backbone - compartment: g - formula: HNO2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3722 - name: ceramide backbone - compartment: c - formula: HNO2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3723 - name: inositol phosphomannosylinositol phosphoceramide backbone - compartment: c - formula: C18H33NO23P2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3724 - name: inositol-P-ceramide backbone - compartment: c - formula: C6H12NO10P + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3725 - name: mannosylinositol phosphorylceramide backbone - compartment: c - formula: C12H22NO15P + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3726 - name: long-chain base backbone - compartment: er - formula: H4N + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3727 - name: long-chain base backbone - compartment: c - formula: H4N + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3728 - name: long-chain base phosphate backbone - compartment: er - formula: H3NO3P + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3729 - name: long-chain base phosphate backbone - compartment: c - formula: H3NO3P + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3730 - name: phosphatidate backbone - compartment: erm - formula: C3H5O4P + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3731 - name: phosphatidate backbone - compartment: c - formula: C3H5O4P + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3732 - name: diglyceride backbone - compartment: erm - formula: C3H4O + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3733 - name: diglyceride backbone - compartment: c - formula: C3H4O + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3734 - name: sn-2-acyl-1-lysophosphatidylinositol backbone - compartment: erm - formula: C9H11O10P + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3735 - name: sn-2-acyl-1-lysophosphatidylinositol backbone - compartment: c - formula: C9H11O10P + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3736 - name: phosphatidylglycerol backbone - compartment: mm - formula: C6H11O6P + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3737 - name: phosphatidylglycerol backbone - compartment: c - formula: C6H11O6P + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3738 - name: cardiolipin backbone - compartment: mm - formula: C9H14O9P2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3739 - name: cardiolipin backbone - compartment: c - formula: C9H14O9P2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3740 - name: C16:0 chain - compartment: c - formula: C16H32O2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3741 - name: C16:1 chain - compartment: c - formula: C16H30O2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3742 - name: C18:0 chain - compartment: c - formula: C18H36O2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3743 - name: C18:1 chain - compartment: c - formula: C18H34O2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3744 - name: C24:0 chain - compartment: c - formula: C24H48O2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3745 - name: C26:0 chain - compartment: c - formula: C26H52O2 + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3746 - name: lipid backbone - compartment: c + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3747 - name: lipid chain - compartment: c + - annotation: !!omap + - sbo: SBO:0000649 - !!omap - id: s_3748 - name: Cytochrome c @@ -18389,6 +21000,7 @@ - annotation: !!omap - chebi: CHEBI:83739 - kegg.compound: C00524 + - sbo: SBO:0000247 - !!omap - id: s_3749 - name: Apocytochrome c @@ -18398,6 +21010,7 @@ - annotation: !!omap - chebi: CHEBI:15697 - kegg.compound: C02248 + - sbo: SBO:0000247 - !!omap - id: s_3750 - name: diacetyl @@ -18407,6 +21020,7 @@ - annotation: !!omap - chebi: CHEBI:16583 - kegg.compound: C00741 + - sbo: SBO:0000247 - !!omap - id: s_3751 - name: (R)-acetoin @@ -18416,6 +21030,7 @@ - annotation: !!omap - chebi: CHEBI:15686 - kegg.compound: C00810 + - sbo: SBO:0000247 - !!omap - id: s_3752 - name: diacetyl @@ -18425,6 +21040,7 @@ - annotation: !!omap - chebi: CHEBI:16583 - kegg.compound: C00741 + - sbo: SBO:0000247 - !!omap - id: s_3753 - name: NADH @@ -18434,6 +21050,7 @@ - annotation: !!omap - chebi: CHEBI:57945 - kegg.compound: C00004 + - sbo: SBO:0000247 - !!omap - id: s_3754 - name: L-glutamyl-tRNA(Gln) @@ -18443,6 +21060,7 @@ - annotation: !!omap - chebi: CHEBI:29165 - kegg.compound: C06112 + - sbo: SBO:0000247 - !!omap - id: s_3755 - name: L-glutamine @@ -18452,6 +21070,7 @@ - annotation: !!omap - chebi: CHEBI:18050 - kegg.compound: C00064 + - sbo: SBO:0000247 - !!omap - id: s_3756 - name: Gln-tRNA(Gln) @@ -18461,6 +21080,7 @@ - annotation: !!omap - chebi: CHEBI:29166 - kegg.compound: C02282 + - sbo: SBO:0000247 - !!omap - id: s_3757 - name: Met-Ala @@ -18469,6 +21089,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73610 + - sbo: SBO:0000247 - !!omap - id: s_3758 - name: L-methionine @@ -18478,6 +21099,7 @@ - annotation: !!omap - chebi: CHEBI:16643 - kegg.compound: C00073 + - sbo: SBO:0000247 - !!omap - id: s_3759 - name: L-alanine @@ -18487,6 +21109,7 @@ - annotation: !!omap - chebi: CHEBI:16977 - kegg.compound: C00041 + - sbo: SBO:0000247 - !!omap - id: s_3760 - name: ADP-D-ribose 1''-phosphate @@ -18495,6 +21118,7 @@ - charge: -4 - annotation: !!omap - chebi: CHEBI:58753 + - sbo: SBO:0000247 - !!omap - id: s_3761 - name: ADP-ribose @@ -18504,6 +21128,7 @@ - annotation: !!omap - chebi: CHEBI:57967 - kegg.compound: C00301 + - sbo: SBO:0000247 - !!omap - id: s_3762 - name: quinone @@ -18513,6 +21138,7 @@ - annotation: !!omap - chebi: CHEBI:16509 - kegg.compound: C00472 + - sbo: SBO:0000247 - !!omap - id: s_3763 - name: 1,4-benzosemiquinone @@ -18521,6 +21147,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:17977 + - sbo: SBO:0000247 - !!omap - id: s_3764 - name: UDP-N-acetyl-alpha-D-glucosamine @@ -18530,6 +21157,7 @@ - annotation: !!omap - chebi: CHEBI:57705 - kegg.compound: C00043 + - sbo: SBO:0000247 - !!omap - id: s_3765 - name: N-Acetyl-D-glucosaminyldiphosphodolichol @@ -18539,6 +21167,7 @@ - annotation: !!omap - chebi: CHEBI:18278 - kegg.compound: C04500 + - sbo: SBO:0000247 - !!omap - id: s_3766 - name: UDP @@ -18548,12 +21177,15 @@ - annotation: !!omap - chebi: CHEBI:58223 - kegg.compound: C00015 + - sbo: SBO:0000247 - !!omap - id: s_3767 - name: N,N'-Chitobiosyldiphosphodolichol - compartment: er - formula: C36H64N2O17P2R - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3768 - name: D-ribofuranose 5-phosphate @@ -18562,6 +21194,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:78346 + - sbo: SBO:0000247 - !!omap - id: s_3769 - name: Oxalate @@ -18571,6 +21204,7 @@ - annotation: !!omap - chebi: CHEBI:30623 - kegg.compound: C00209 + - sbo: SBO:0000247 - !!omap - id: s_3770 - name: Oxalyl-CoA @@ -18580,12 +21214,15 @@ - annotation: !!omap - chebi: CHEBI:57388 - kegg.compound: C00313 + - sbo: SBO:0000247 - !!omap - id: s_3771 - name: G00171 - compartment: er - formula: C86H142N4O67R - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3772 - name: D-glucose @@ -18595,18 +21232,23 @@ - annotation: !!omap - chebi: CHEBI:4167 - kegg.compound: C00031 + - sbo: SBO:0000247 - !!omap - id: s_3773 - name: G00010 - compartment: er - formula: C80H132N4O62R - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3774 - name: G00011 - compartment: er - formula: C74H122N4O57R - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3775 - name: sodium @@ -18616,6 +21258,7 @@ - annotation: !!omap - chebi: CHEBI:29101 - kegg.compound: C01330 + - sbo: SBO:0000247 - !!omap - id: s_3776 - name: potassium @@ -18625,6 +21268,7 @@ - annotation: !!omap - chebi: CHEBI:29103 - kegg.compound: C00238 + - sbo: SBO:0000247 - !!omap - id: s_3777 - name: chloride @@ -18634,6 +21278,7 @@ - annotation: !!omap - chebi: CHEBI:17996 - kegg.compound: C00698 + - sbo: SBO:0000247 - !!omap - id: s_3778 - name: chloride @@ -18643,6 +21288,7 @@ - annotation: !!omap - chebi: CHEBI:17996 - kegg.compound: C00698 + - sbo: SBO:0000247 - !!omap - id: s_3779 - name: D-fructose @@ -18652,6 +21298,7 @@ - annotation: !!omap - chebi: CHEBI:15824 - kegg.compound: C00095 + - sbo: SBO:0000247 - !!omap - id: s_3780 - name: D-galactose @@ -18661,6 +21308,7 @@ - annotation: !!omap - chebi: CHEBI:4139 - kegg.compound: C00124 + - sbo: SBO:0000247 - !!omap - id: s_3781 - name: UMP @@ -18670,6 +21318,7 @@ - annotation: !!omap - chebi: CHEBI:57865 - kegg.compound: C00105 + - sbo: SBO:0000247 - !!omap - id: s_3782 - name: cadmium(2+) @@ -18678,6 +21327,7 @@ - charge: 2 - annotation: !!omap - chebi: CHEBI:48775 + - sbo: SBO:0000247 - !!omap - id: s_3783 - name: cadmium(2+) @@ -18686,12 +21336,15 @@ - charge: 2 - annotation: !!omap - chebi: CHEBI:48775 + - sbo: SBO:0000247 - !!omap - id: s_3784 - name: (sulfur carrier)-H - compartment: m - formula: R - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3785 - name: L-cysteine @@ -18701,12 +21354,15 @@ - annotation: !!omap - chebi: CHEBI:17561 - kegg.compound: C00097 + - sbo: SBO:0000247 - !!omap - id: s_3786 - name: (sulfur carrier)-SH - compartment: m - formula: SR - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3787 - name: cholesterol @@ -18716,6 +21372,7 @@ - annotation: !!omap - chebi: CHEBI:16113 - kegg.compound: C00187 + - sbo: SBO:0000247 - !!omap - id: s_3788 - name: cholesterol @@ -18725,18 +21382,23 @@ - annotation: !!omap - chebi: CHEBI:16113 - kegg.compound: C00187 + - sbo: SBO:0000247 - !!omap - id: s_3789 - name: 3-chlorobenzyl alcohol - compartment: c - formula: C7H7ClO - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3790 - name: 3-chlorobenzaldehyde - compartment: c - formula: C7H5ClO - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3791 - name: 3-hydroxybenzyl alcohol @@ -18746,6 +21408,7 @@ - annotation: !!omap - chebi: CHEBI:17069 - kegg.compound: C03351 + - sbo: SBO:0000247 - !!omap - id: s_3792 - name: 3-hydroxybenzaldehyde @@ -18755,6 +21418,7 @@ - annotation: !!omap - chebi: CHEBI:16207 - kegg.compound: C03067 + - sbo: SBO:0000247 - !!omap - id: s_3793 - name: 3-methylbenzyl alcohol @@ -18764,6 +21428,7 @@ - annotation: !!omap - chebi: CHEBI:27995 - kegg.compound: C07216 + - sbo: SBO:0000247 - !!omap - id: s_3794 - name: 3-methylbenzaldehyde @@ -18773,6 +21438,7 @@ - annotation: !!omap - chebi: CHEBI:28476 - kegg.compound: C07209 + - sbo: SBO:0000247 - !!omap - id: s_3795 - name: 4-isopropylbenzyl alcohol @@ -18781,6 +21447,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:27628 + - sbo: SBO:0000247 - !!omap - id: s_3796 - name: p-cumic aldehyde @@ -18790,6 +21457,7 @@ - annotation: !!omap - chebi: CHEBI:28671 - kegg.compound: C06577 + - sbo: SBO:0000247 - !!omap - id: s_3797 - name: 4-methylbenzyl alcohol @@ -18799,6 +21467,7 @@ - annotation: !!omap - chebi: CHEBI:1895 - kegg.compound: C06757 + - sbo: SBO:0000247 - !!omap - id: s_3798 - name: 4-methylbenzaldehyde @@ -18808,6 +21477,7 @@ - annotation: !!omap - chebi: CHEBI:28617 - kegg.compound: C06758 + - sbo: SBO:0000247 - !!omap - id: s_3799 - name: benzyl alcohol @@ -18817,6 +21487,7 @@ - annotation: !!omap - chebi: CHEBI:17987 - kegg.compound: C00556 + - sbo: SBO:0000247 - !!omap - id: s_3800 - name: benzaldehyde @@ -18826,6 +21497,7 @@ - annotation: !!omap - chebi: CHEBI:17169 - kegg.compound: C00261 + - sbo: SBO:0000247 - !!omap - id: s_3801 - name: Mn(2+) @@ -18835,6 +21507,7 @@ - annotation: !!omap - chebi: CHEBI:29035 - kegg.compound: C19610 + - sbo: SBO:0000247 - !!omap - id: s_3802 - name: Mn(2+) @@ -18844,6 +21517,7 @@ - annotation: !!omap - chebi: CHEBI:29035 - kegg.compound: C19610 + - sbo: SBO:0000247 - !!omap - id: s_3805 - name: Mannitol @@ -18853,6 +21527,7 @@ - annotation: !!omap - chebi: CHEBI:16899 - kegg.compound: C00392 + - sbo: SBO:0000247 - !!omap - id: s_3806 - name: 4-hydroxy-4-methyl-2-oxoglutarate @@ -18862,6 +21537,7 @@ - annotation: !!omap - chebi: CHEBI:58276 - kegg.compound: C06033 + - sbo: SBO:0000247 - !!omap - id: s_3807 - name: L-methionine (S)-S-oxide @@ -18871,6 +21547,7 @@ - annotation: !!omap - chebi: CHEBI:49031 - kegg.compound: C15999 + - sbo: SBO:0000247 - !!omap - id: s_3808 - name: tRNA(Pro) @@ -18880,6 +21557,7 @@ - annotation: !!omap - chebi: CHEBI:29177 - kegg.compound: C01649 + - sbo: SBO:0000247 - !!omap - id: s_3809 - name: Pro-tRNA(Pro) @@ -18889,6 +21567,7 @@ - annotation: !!omap - chebi: CHEBI:29154 - kegg.compound: C02702 + - sbo: SBO:0000247 - !!omap - id: s_3810 - name: 5-oxo-L-proline @@ -18898,6 +21577,7 @@ - annotation: !!omap - chebi: CHEBI:58402 - kegg.compound: C01879 + - sbo: SBO:0000247 - !!omap - id: s_3811 - name: 4a-Hydroxytetrahydrobiopterin @@ -18907,6 +21587,7 @@ - annotation: !!omap - chebi: CHEBI:15642 - kegg.compound: C15522 + - sbo: SBO:0000247 - !!omap - id: s_3812 - name: Dihydrobiopterin @@ -18916,6 +21597,7 @@ - annotation: !!omap - chebi: CHEBI:20680 - kegg.compound: C00268 + - sbo: SBO:0000247 - !!omap - id: s_3813 - name: superoxide @@ -18925,6 +21607,7 @@ - annotation: !!omap - chebi: CHEBI:18421 - kegg.compound: C00704 + - sbo: SBO:0000247 - !!omap - id: s_3814 - name: 2-deoxy-D-glucose 6-phosphate @@ -18934,6 +21617,7 @@ - annotation: !!omap - chebi: CHEBI:84760 - kegg.compound: C06369 + - sbo: SBO:0000247 - !!omap - id: s_3815 - name: 2-deoxy-D-glucose @@ -18943,6 +21627,7 @@ - annotation: !!omap - chebi: CHEBI:84755 - kegg.compound: C00586 + - sbo: SBO:0000247 - !!omap - id: s_3816 - name: [cytochrome c]-L-lysine @@ -18951,6 +21636,7 @@ - charge: 1 - annotation: !!omap - chebi: CHEBI:29969 + - sbo: SBO:0000247 - !!omap - id: s_3817 - name: [cytochrome c]-N6-methyl-L-lysine @@ -18959,6 +21645,7 @@ - charge: 1 - annotation: !!omap - chebi: CHEBI:61929 + - sbo: SBO:0000247 - !!omap - id: s_3818 - name: S-adenosyl-L-methionine @@ -18968,6 +21655,7 @@ - annotation: !!omap - chebi: CHEBI:67040 - kegg.compound: C00019 + - sbo: SBO:0000247 - !!omap - id: s_3819 - name: L-lysine-[histone] @@ -18976,6 +21664,7 @@ - charge: 1 - annotation: !!omap - chebi: CHEBI:29969 + - sbo: SBO:0000247 - !!omap - id: s_3820 - name: S-adenosyl-L-homocysteine @@ -18985,6 +21674,7 @@ - annotation: !!omap - chebi: CHEBI:16680 - kegg.compound: C00021 + - sbo: SBO:0000247 - !!omap - id: s_3821 - name: N6-methyl-L-lysine-[histone] @@ -18993,6 +21683,7 @@ - charge: 1 - annotation: !!omap - chebi: CHEBI:61929 + - sbo: SBO:0000247 - !!omap - id: s_3822 - name: Zn(2+) @@ -19002,6 +21693,7 @@ - annotation: !!omap - chebi: CHEBI:29105 - kegg.compound: C00038 + - sbo: SBO:0000247 - !!omap - id: s_3823 - name: Zn(2+) @@ -19011,6 +21703,7 @@ - annotation: !!omap - chebi: CHEBI:29105 - kegg.compound: C00038 + - sbo: SBO:0000247 - !!omap - id: s_3824 - name: Ferricytochrome b5 @@ -19020,6 +21713,7 @@ - annotation: !!omap - chebi: CHEBI:18097 - kegg.compound: C00996 + - sbo: SBO:0000247 - !!omap - id: s_3825 - name: Ferrocytochrome b5 @@ -19028,6 +21722,7 @@ - charge: 2 - annotation: !!omap - kegg.compound: C00999 + - sbo: SBO:0000247 - !!omap - id: s_3826 - name: Ferricytochrome b5 @@ -19037,6 +21732,7 @@ - annotation: !!omap - chebi: CHEBI:18097 - kegg.compound: C00996 + - sbo: SBO:0000247 - !!omap - id: s_3827 - name: Ferrocytochrome b5 @@ -19045,6 +21741,7 @@ - charge: 2 - annotation: !!omap - kegg.compound: C00999 + - sbo: SBO:0000247 - !!omap - id: s_3828 - name: (S)-benzoin @@ -19053,6 +21750,7 @@ - charge: 0 - annotation: !!omap - kegg.compound: C20227 + - sbo: SBO:0000247 - !!omap - id: s_3829 - name: benzil @@ -19062,6 +21760,7 @@ - annotation: !!omap - chebi: CHEBI:51507 - kegg.compound: C20226 + - sbo: SBO:0000247 - !!omap - id: s_3830 - name: RX @@ -19071,6 +21770,7 @@ - annotation: !!omap - chebi: CHEBI:17792 - kegg.compound: C01322 + - sbo: SBO:0000247 - !!omap - id: s_3831 - name: glutathione @@ -19080,6 +21780,7 @@ - annotation: !!omap - chebi: CHEBI:57925 - kegg.compound: C00051 + - sbo: SBO:0000247 - !!omap - id: s_3832 - name: HX @@ -19089,6 +21790,7 @@ - annotation: !!omap - chebi: CHEBI:16042 - kegg.compound: C00462 + - sbo: SBO:0000247 - !!omap - id: s_3833 - name: R-S-glutathione @@ -19098,6 +21800,7 @@ - annotation: !!omap - chebi: CHEBI:17021 - kegg.compound: C02320 + - sbo: SBO:0000247 - !!omap - id: s_3834 - name: RX @@ -19107,6 +21810,7 @@ - annotation: !!omap - chebi: CHEBI:17792 - kegg.compound: C01322 + - sbo: SBO:0000247 - !!omap - id: s_3835 - name: HX @@ -19116,6 +21820,7 @@ - annotation: !!omap - chebi: CHEBI:16042 - kegg.compound: C00462 + - sbo: SBO:0000247 - !!omap - id: s_3836 - name: R-S-glutathione @@ -19125,6 +21830,7 @@ - annotation: !!omap - chebi: CHEBI:17021 - kegg.compound: C02320 + - sbo: SBO:0000247 - !!omap - id: s_3837 - name: L-Methionine S-oxide @@ -19134,6 +21840,7 @@ - annotation: !!omap - chebi: CHEBI:17016 - kegg.compound: C02989 + - sbo: SBO:0000247 - !!omap - id: s_3838 - name: Ala-Gly @@ -19142,6 +21849,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73757 + - sbo: SBO:0000247 - !!omap - id: s_3839 - name: L-glycine @@ -19151,6 +21859,7 @@ - annotation: !!omap - chebi: CHEBI:15428 - kegg.compound: C00037 + - sbo: SBO:0000247 - !!omap - id: s_3840 - name: Ala-Leu @@ -19159,6 +21868,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:73770 + - sbo: SBO:0000247 - !!omap - id: s_3841 - name: Threo-3-hydroxy-L-aspartate @@ -19168,6 +21878,7 @@ - annotation: !!omap - chebi: CHEBI:57251 - kegg.compound: C11511 + - sbo: SBO:0000247 - !!omap - id: s_3842 - name: RX @@ -19177,6 +21888,7 @@ - annotation: !!omap - chebi: CHEBI:17792 - kegg.compound: C01322 + - sbo: SBO:0000247 - !!omap - id: s_3843 - name: glutathione @@ -19186,6 +21898,7 @@ - annotation: !!omap - chebi: CHEBI:57925 - kegg.compound: C00051 + - sbo: SBO:0000247 - !!omap - id: s_3844 - name: HX @@ -19195,6 +21908,7 @@ - annotation: !!omap - chebi: CHEBI:16042 - kegg.compound: C00462 + - sbo: SBO:0000247 - !!omap - id: s_3845 - name: R-S-glutathione @@ -19204,6 +21918,7 @@ - annotation: !!omap - chebi: CHEBI:17021 - kegg.compound: C02320 + - sbo: SBO:0000247 - !!omap - id: s_3846 - name: dehydroascorbate @@ -19213,6 +21928,7 @@ - annotation: !!omap - chebi: CHEBI:27956 - kegg.compound: C05422 + - sbo: SBO:0000247 - !!omap - id: s_3847 - name: ascorbate @@ -19222,6 +21938,7 @@ - annotation: !!omap - chebi: CHEBI:38290 - kegg.compound: C00072 + - sbo: SBO:0000247 - !!omap - id: s_3848 - name: dehydroascorbate @@ -19231,6 +21948,7 @@ - annotation: !!omap - chebi: CHEBI:27956 - kegg.compound: C05422 + - sbo: SBO:0000247 - !!omap - id: s_3849 - name: glutathione disulfide @@ -19240,6 +21958,7 @@ - annotation: !!omap - chebi: CHEBI:58297 - kegg.compound: C00127 + - sbo: SBO:0000247 - !!omap - id: s_3850 - name: ascorbate @@ -19249,6 +21968,7 @@ - annotation: !!omap - chebi: CHEBI:38290 - kegg.compound: C00072 + - sbo: SBO:0000247 - !!omap - id: s_3851 - name: Cyanamide @@ -19258,6 +21978,7 @@ - annotation: !!omap - chebi: CHEBI:16698 - kegg.compound: C01566 + - sbo: SBO:0000247 - !!omap - id: s_3852 - name: aldehydo-D-ribose 5-phosphate @@ -19267,6 +21988,7 @@ - annotation: !!omap - chebi: CHEBI:58273 - kegg.compound: C00117 + - sbo: SBO:0000247 - !!omap - id: s_3853 - name: R-S-Cysteinylglycine @@ -19276,6 +21998,7 @@ - annotation: !!omap - chebi: CHEBI:8744 - kegg.compound: C05729 + - sbo: SBO:0000247 - !!omap - id: s_3854 - name: S-Substituted L-cysteine @@ -19285,6 +22008,7 @@ - annotation: !!omap - chebi: CHEBI:47910 - kegg.compound: C05726 + - sbo: SBO:0000247 - !!omap - id: s_3855 - name: iron(3+) @@ -19294,17 +22018,22 @@ - annotation: !!omap - chebi: CHEBI:29034 - kegg.compound: C14819 + - sbo: SBO:0000247 - !!omap - id: s_3856 - name: Glycyl-tRNA(Ala) - compartment: c - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3857 - name: D-tyrosyl-tRNA(Tyr) - compartment: c - formula: C9H10NO3R - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3858 - name: D-tyrosine @@ -19314,6 +22043,7 @@ - annotation: !!omap - chebi: CHEBI:28479 - kegg.compound: C06420 + - sbo: SBO:0000247 - !!omap - id: s_3859 - name: 4-nitrophenyl phosphate @@ -19323,6 +22053,7 @@ - annotation: !!omap - chebi: CHEBI:61146 - kegg.compound: C03360 + - sbo: SBO:0000247 - !!omap - id: s_3860 - name: 4-nitrophenol @@ -19332,6 +22063,7 @@ - annotation: !!omap - chebi: CHEBI:57917 - kegg.compound: C00870 + - sbo: SBO:0000247 - !!omap - id: s_3861 - name: L-iditol @@ -19341,6 +22073,7 @@ - annotation: !!omap - chebi: CHEBI:18202 - kegg.compound: C01507 + - sbo: SBO:0000247 - !!omap - id: s_3862 - name: alpha-D-Galactose @@ -19350,6 +22083,7 @@ - annotation: !!omap - chebi: CHEBI:28061 - kegg.compound: C00984 + - sbo: SBO:0000247 - !!omap - id: s_3863 - name: 3-hydroxy-2-methylpropanoyl-CoA @@ -19359,6 +22093,7 @@ - annotation: !!omap - chebi: CHEBI:57340 - kegg.compound: C04047 + - sbo: SBO:0000247 - !!omap - id: s_3864 - name: 3-hydroxy-2-methylpropanoate @@ -19368,6 +22103,7 @@ - annotation: !!omap - chebi: CHEBI:11805 - kegg.compound: C01188 + - sbo: SBO:0000247 - !!omap - id: s_3865 - name: sterols @@ -19377,6 +22113,7 @@ - annotation: !!omap - chebi: CHEBI:15889 - kegg.compound: C00370 + - sbo: SBO:0000247 - !!omap - id: s_3866 - name: sterols @@ -19386,6 +22123,7 @@ - annotation: !!omap - chebi: CHEBI:15889 - kegg.compound: C00370 + - sbo: SBO:0000247 - !!omap - id: s_3867 - name: 2-Phenylacetamide @@ -19395,6 +22133,7 @@ - annotation: !!omap - chebi: CHEBI:16562 - kegg.compound: C02505 + - sbo: SBO:0000247 - !!omap - id: s_3868 - name: (Indol-3-yl)acetamide @@ -19404,6 +22143,7 @@ - annotation: !!omap - chebi: CHEBI:16031 - kegg.compound: C02693 + - sbo: SBO:0000247 - !!omap - id: s_3869 - name: Monocarboxylic acid amide @@ -19412,6 +22152,7 @@ - charge: 0 - annotation: !!omap - kegg.compound: C03620 + - sbo: SBO:0000247 - !!omap - id: s_3870 - name: Carboxylate @@ -19421,6 +22162,7 @@ - annotation: !!omap - chebi: CHEBI:35757 - kegg.compound: C00060 + - sbo: SBO:0000247 - !!omap - id: s_3871 - name: Acrylic acid @@ -19430,6 +22172,7 @@ - annotation: !!omap - chebi: CHEBI:37080 - kegg.compound: C00511 + - sbo: SBO:0000247 - !!omap - id: s_3872 - name: Acrylamide @@ -19439,6 +22182,7 @@ - annotation: !!omap - chebi: CHEBI:28619 - kegg.compound: C01659 + - sbo: SBO:0000247 - !!omap - id: s_3873 - name: Benzamide @@ -19448,6 +22192,7 @@ - annotation: !!omap - chebi: CHEBI:28179 - kegg.compound: C09815 + - sbo: SBO:0000247 - !!omap - id: s_3874 - name: Benzoate @@ -19457,6 +22202,7 @@ - annotation: !!omap - chebi: CHEBI:16150 - kegg.compound: C00180 + - sbo: SBO:0000247 - !!omap - id: s_3875 - name: D-gluconate @@ -19466,6 +22212,7 @@ - annotation: !!omap - chebi: CHEBI:18391 - kegg.compound: C00257 + - sbo: SBO:0000247 - !!omap - id: s_3876 - name: Protein C-terminal S-farnesyl-L-cysteine @@ -19475,6 +22222,7 @@ - annotation: !!omap - chebi: CHEBI:17171 - kegg.compound: C04506 + - sbo: SBO:0000247 - !!omap - id: s_3877 - name: Protein C-terminal S-farnesyl-L-cysteine methyl ester @@ -19484,6 +22232,7 @@ - annotation: !!omap - chebi: CHEBI:15818 - kegg.compound: C04748 + - sbo: SBO:0000247 - !!omap - id: s_3878 - name: 1-phosphatidyl-1D-myo-inositol @@ -19493,6 +22242,7 @@ - annotation: !!omap - chebi: CHEBI:57880 - kegg.compound: C01194 + - sbo: SBO:0000247 - !!omap - id: s_3879 - name: G00143 @@ -19501,6 +22251,7 @@ - charge: -1 - annotation: !!omap - chebi: CHEBI:57265 + - sbo: SBO:0000247 - !!omap - id: s_3880 - name: Ca(2+) @@ -19510,6 +22261,7 @@ - annotation: !!omap - chebi: CHEBI:29108 - kegg.compound: C00076 + - sbo: SBO:0000247 - !!omap - id: s_3881 - name: ATP @@ -19519,6 +22271,7 @@ - annotation: !!omap - chebi: CHEBI:30616 - kegg.compound: C00002 + - sbo: SBO:0000247 - !!omap - id: s_3882 - name: Ca(2+) @@ -19528,6 +22281,7 @@ - annotation: !!omap - chebi: CHEBI:29108 - kegg.compound: C00076 + - sbo: SBO:0000247 - !!omap - id: s_3883 - name: ADP @@ -19537,6 +22291,7 @@ - annotation: !!omap - chebi: CHEBI:456216 - kegg.compound: C00008 + - sbo: SBO:0000247 - !!omap - id: s_3884 - name: Protein @@ -19545,6 +22300,7 @@ - charge: 1 - annotation: !!omap - kegg.compound: C00017 + - sbo: SBO:0000247 - !!omap - id: s_3885 - name: L-Arginyl-protein @@ -19554,6 +22310,7 @@ - annotation: !!omap - chebi: CHEBI:17518 - kegg.compound: C16739 + - sbo: SBO:0000247 - !!omap - id: s_3886 - name: Protein asparagine @@ -19563,12 +22320,15 @@ - annotation: !!omap - chebi: CHEBI:50347 - kegg.compound: C03021 + - sbo: SBO:0000247 - !!omap - id: s_3887 - name: G00008 - compartment: er - formula: C108H182N2O77P2R - charge: -2 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3888 - name: Dolichyl diphosphate @@ -19577,6 +22337,7 @@ - charge: -3 - annotation: !!omap - chebi: CHEBI:57497 + - sbo: SBO:0000247 - !!omap - id: s_3889 - name: G00009 @@ -19585,6 +22346,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:132537 + - sbo: SBO:0000247 - !!omap - id: s_3890 - name: GDP-alpha-D-mannose @@ -19594,12 +22356,15 @@ - annotation: !!omap - chebi: CHEBI:57527 - kegg.compound: C00096 + - sbo: SBO:0000247 - !!omap - id: s_3891 - name: G10694 - compartment: er - formula: C68H112N4O52R - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3892 - name: GDP @@ -19609,30 +22374,39 @@ - annotation: !!omap - chebi: CHEBI:58189 - kegg.compound: C00035 + - sbo: SBO:0000247 - !!omap - id: s_3893 - name: G01813 - compartment: er - formula: C74H122N4O57R - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3894 - name: G00003 - compartment: er - formula: C42H72N2O22P2R - charge: -2 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3895 - name: G00004 - compartment: er - formula: C48H82N2O27P2R - charge: -2 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3896 - name: G00005 - compartment: er - formula: C54H92N2O32P2R - charge: -2 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3897 - name: 2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate @@ -19642,6 +22416,7 @@ - annotation: !!omap - chebi: CHEBI:60331 - kegg.compound: C16699 + - sbo: SBO:0000247 - !!omap - id: s_3898 - name: D-mannose 6-phosphate @@ -19651,6 +22426,7 @@ - annotation: !!omap - chebi: CHEBI:17369 - kegg.compound: C00275 + - sbo: SBO:0000247 - !!omap - id: s_3899 - name: D-Glycerate @@ -19660,6 +22436,7 @@ - annotation: !!omap - chebi: CHEBI:16659 - kegg.compound: C00258 + - sbo: SBO:0000247 - !!omap - id: s_3900 - name: alpha-D-mannoside @@ -19669,6 +22446,7 @@ - annotation: !!omap - chebi: CHEBI:27535 - kegg.compound: C02603 + - sbo: SBO:0000247 - !!omap - id: s_3901 - name: alpha-D-mannopyranose @@ -19678,12 +22456,15 @@ - annotation: !!omap - chebi: CHEBI:28729 - kegg.compound: C00936 + - sbo: SBO:0000247 - !!omap - id: s_3902 - name: non glycosylated sugar acceptor - compartment: v - formula: HOR - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3903 - name: L-Threonylcarbamoyladenylate @@ -19692,6 +22473,7 @@ - charge: -2 - annotation: !!omap - kegg.compound: C20641 + - sbo: SBO:0000247 - !!omap - id: s_3904 - name: D-Serine @@ -19701,6 +22483,7 @@ - annotation: !!omap - chebi: CHEBI:16523 - kegg.compound: C00740 + - sbo: SBO:0000247 - !!omap - id: s_3905 - name: O-acetyl-L-serine @@ -19710,6 +22493,7 @@ - annotation: !!omap - chebi: CHEBI:17981 - kegg.compound: C00979 + - sbo: SBO:0000247 - !!omap - id: s_3906 - name: hydrogen sulfide @@ -19719,6 +22503,7 @@ - annotation: !!omap - chebi: CHEBI:29919 - kegg.compound: C00283 + - sbo: SBO:0000247 - !!omap - id: s_3907 - name: phosphatidate @@ -19728,6 +22513,7 @@ - annotation: !!omap - chebi: CHEBI:16337 - kegg.compound: C00416 + - sbo: SBO:0000247 - !!omap - id: s_3908 - name: CDP-diacylglycerol @@ -19737,6 +22523,7 @@ - annotation: !!omap - chebi: CHEBI:58332 - kegg.compound: C00269 + - sbo: SBO:0000247 - !!omap - id: s_3909 - name: Sulfur donor @@ -19745,6 +22532,7 @@ - annotation: !!omap - chebi: CHEBI:80867 - kegg.compound: C17023 + - sbo: SBO:0000247 - !!omap - id: s_3910 - name: ADP-5-ethyl-4-methylthiazole-2-carboxylate @@ -19754,6 +22542,7 @@ - annotation: !!omap - chebi: CHEBI:134399 - kegg.compound: C20784 + - sbo: SBO:0000247 - !!omap - id: s_3911 - name: Dolichyl beta-D-glucosyl phosphate @@ -19763,12 +22552,15 @@ - annotation: !!omap - chebi: CHEBI:57525 - kegg.compound: C01246 + - sbo: SBO:0000247 - !!omap - id: s_3912 - name: G10599 - compartment: er - formula: C102H172N2O72P2R - charge: -2 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3913 - name: nitric oxide @@ -19778,6 +22570,7 @@ - annotation: !!omap - chebi: CHEBI:16480 - kegg.compound: C00533 + - sbo: SBO:0000247 - !!omap - id: s_3914 - name: nitrate @@ -19787,6 +22580,7 @@ - annotation: !!omap - chebi: CHEBI:17632 - kegg.compound: C00244 + - sbo: SBO:0000247 - !!omap - id: s_3915 - name: (R)-Lipoate @@ -19796,6 +22590,7 @@ - annotation: !!omap - chebi: CHEBI:83088 - kegg.compound: C16241 + - sbo: SBO:0000247 - !!omap - id: s_3916 - name: Lipoyl-AMP @@ -19805,6 +22600,7 @@ - annotation: !!omap - chebi: CHEBI:83091 - kegg.compound: C16238 + - sbo: SBO:0000247 - !!omap - id: s_3917 - name: Apoprotein @@ -19814,6 +22610,7 @@ - annotation: !!omap - chebi: CHEBI:13850 - kegg.compound: C16240 + - sbo: SBO:0000247 - !!omap - id: s_3918 - name: Protein N6-(lipoyl)lysine @@ -19823,6 +22620,7 @@ - annotation: !!omap - chebi: CHEBI:80399 - kegg.compound: C16237 + - sbo: SBO:0000247 - !!omap - id: s_3923 - name: N-(4-oxoglutarate)-L-cysteinylglycine @@ -19831,6 +22629,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:138256 + - sbo: SBO:0000247 - !!omap - id: s_3924 - name: N-(4-oxoglutarate)-L-cysteinylglycine @@ -19839,6 +22638,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:138256 + - sbo: SBO:0000247 - !!omap - id: s_3925 - name: L-cysteinylglycine @@ -19848,6 +22648,7 @@ - annotation: !!omap - chebi: CHEBI:4047 - kegg.compound: C01419 + - sbo: SBO:0000247 - !!omap - id: s_3926 - name: chloride @@ -19857,6 +22658,7 @@ - annotation: !!omap - chebi: CHEBI:17996 - kegg.compound: C00698 + - sbo: SBO:0000247 - !!omap - id: s_3927 - name: ribonucleoside 5'-triphosphate @@ -19866,6 +22668,7 @@ - annotation: !!omap - chebi: CHEBI:61557 - kegg.compound: C03802 + - sbo: SBO:0000247 - !!omap - id: s_3928 - name: ribonucleoside 5'-phosphate @@ -19874,6 +22677,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:58043 + - sbo: SBO:0000247 - !!omap - id: s_3929 - name: 2'-deoxyribonucleoside 5'-triphosphate @@ -19883,6 +22687,7 @@ - annotation: !!omap - chebi: CHEBI:61560 - kegg.compound: C00677 + - sbo: SBO:0000247 - !!omap - id: s_3930 - name: 2'-deoxyribonucleoside 5'-phosphate @@ -19892,6 +22697,7 @@ - annotation: !!omap - chebi: CHEBI:65317 - kegg.compound: C00676 + - sbo: SBO:0000247 - !!omap - id: s_3931 - name: superoxide @@ -19901,12 +22707,15 @@ - annotation: !!omap - chebi: CHEBI:18421 - kegg.compound: C00704 + - sbo: SBO:0000247 - !!omap - id: s_3932 - name: G00012 - compartment: er - formula: C50H66N4O29 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3933 - name: D-mannose @@ -19916,6 +22725,7 @@ - annotation: !!omap - chebi: CHEBI:4208 - kegg.compound: C00159 + - sbo: SBO:0000247 - !!omap - id: s_3934 - name: Ethylnitronate @@ -19925,6 +22735,7 @@ - annotation: !!omap - chebi: CHEBI:16268 - kegg.compound: C18091 + - sbo: SBO:0000247 - !!omap - id: s_3935 - name: Nitrite @@ -19934,6 +22745,7 @@ - annotation: !!omap - chebi: CHEBI:16301 - kegg.compound: C00088 + - sbo: SBO:0000247 - !!omap - id: s_3936 - name: iron(3+) @@ -19942,6 +22754,7 @@ - charge: 3 - annotation: !!omap - kegg.compound: C14819 + - sbo: SBO:0000247 - !!omap - id: s_3937 - name: Acyl-CoA @@ -19951,6 +22764,7 @@ - annotation: !!omap - chebi: CHEBI:58342 - kegg.compound: C00040 + - sbo: SBO:0000247 - !!omap - id: s_3938 - name: 1-acyl-sn-glycerol 3-phosphate @@ -19960,6 +22774,7 @@ - annotation: !!omap - chebi: CHEBI:57970 - kegg.compound: C00681 + - sbo: SBO:0000247 - !!omap - id: s_3939 - name: 1,2-diacyl-sn-glycerol 3-phosphate @@ -19969,6 +22784,7 @@ - annotation: !!omap - chebi: CHEBI:58608 - kegg.compound: C00416 + - sbo: SBO:0000247 - !!omap - id: s_3940 - name: Peptide diphthine @@ -19978,6 +22794,7 @@ - annotation: !!omap - chebi: CHEBI:18054 - kegg.compound: C01573 + - sbo: SBO:0000247 - !!omap - id: s_3941 - name: Peptide diphthamide @@ -19987,6 +22804,7 @@ - annotation: !!omap - chebi: CHEBI:82696 - kegg.compound: C02872 + - sbo: SBO:0000247 - !!omap - id: s_3942 - name: 8-oxo-dGTP @@ -19995,6 +22813,7 @@ - charge: -4 - annotation: !!omap - kegg.compound: C19967 + - sbo: SBO:0000247 - !!omap - id: s_3943 - name: 8-oxo-dGMP @@ -20003,6 +22822,7 @@ - charge: -2 - annotation: !!omap - kegg.compound: C19968 + - sbo: SBO:0000247 - !!omap - id: s_3944 - name: Apoprotein @@ -20012,6 +22832,7 @@ - annotation: !!omap - chebi: CHEBI:13850 - kegg.compound: C16240 + - sbo: SBO:0000247 - !!omap - id: s_3945 - name: Protein N6-(octanoyl)lysine @@ -20021,6 +22842,7 @@ - annotation: !!omap - chebi: CHEBI:80398 - kegg.compound: C16236 + - sbo: SBO:0000247 - !!omap - id: s_3946 - name: Lipoyl-[acp] @@ -20030,6 +22852,7 @@ - annotation: !!omap - chebi: CHEBI:80400 - kegg.compound: C16239 + - sbo: SBO:0000247 - !!omap - id: s_3947 - name: Protein N6-(lipoyl)lysine @@ -20039,6 +22862,7 @@ - annotation: !!omap - chebi: CHEBI:80399 - kegg.compound: C16237 + - sbo: SBO:0000247 - !!omap - id: s_3948 - name: beta-D-Fructose 6-phosphate @@ -20048,6 +22872,7 @@ - annotation: !!omap - chebi: CHEBI:57634 - kegg.compound: C05345 + - sbo: SBO:0000247 - !!omap - id: s_3949 - name: beta-D-Glucose @@ -20057,6 +22882,7 @@ - annotation: !!omap - chebi: CHEBI:15903 - kegg.compound: C00221 + - sbo: SBO:0000247 - !!omap - id: s_3950 - name: beta-D-Glucose 6-phosphate @@ -20066,6 +22892,7 @@ - annotation: !!omap - chebi: CHEBI:58247 - kegg.compound: C01172 + - sbo: SBO:0000247 - !!omap - id: s_3951 - name: alpha-D-Glucose @@ -20075,6 +22902,7 @@ - annotation: !!omap - chebi: CHEBI:17925 - kegg.compound: C00267 + - sbo: SBO:0000247 - !!omap - id: s_3952 - name: alpha-D-Glucose 6-phosphate @@ -20084,6 +22912,7 @@ - annotation: !!omap - chebi: CHEBI:58225 - kegg.compound: C00668 + - sbo: SBO:0000247 - !!omap - id: s_3953 - name: D-Glucosamine @@ -20093,6 +22922,7 @@ - annotation: !!omap - chebi: CHEBI:47977 - kegg.compound: C00329 + - sbo: SBO:0000247 - !!omap - id: s_3954 - name: beta-D-Fructose @@ -20102,6 +22932,7 @@ - annotation: !!omap - chebi: CHEBI:28645 - kegg.compound: C02336 + - sbo: SBO:0000247 - !!omap - id: s_3958 - name: D-Glycerate @@ -20111,6 +22942,7 @@ - annotation: !!omap - chebi: CHEBI:16659 - kegg.compound: C00258 + - sbo: SBO:0000247 - !!omap - id: s_3959 - name: 2-Propynal @@ -20120,6 +22952,7 @@ - annotation: !!omap - chebi: CHEBI:27976 - kegg.compound: C05985 + - sbo: SBO:0000247 - !!omap - id: s_3960 - name: Propynoate @@ -20129,6 +22962,7 @@ - annotation: !!omap - chebi: CHEBI:15364 - kegg.compound: C00804 + - sbo: SBO:0000247 - !!omap - id: s_3961 - name: D-Glucuronolactone @@ -20138,6 +22972,7 @@ - annotation: !!omap - chebi: CHEBI:18268 - kegg.compound: C02670 + - sbo: SBO:0000247 - !!omap - id: s_3962 - name: D-Glucarate @@ -20147,6 +22982,7 @@ - annotation: !!omap - chebi: CHEBI:30612 - kegg.compound: C00818 + - sbo: SBO:0000247 - !!omap - id: s_3963 - name: 4-Trimethylammoniobutanal @@ -20156,6 +22992,7 @@ - annotation: !!omap - chebi: CHEBI:18020 - kegg.compound: C01149 + - sbo: SBO:0000247 - !!omap - id: s_3964 - name: 4-Trimethylammoniobutanoate @@ -20165,6 +23002,7 @@ - annotation: !!omap - chebi: CHEBI:1941 - kegg.compound: C01181 + - sbo: SBO:0000247 - !!omap - id: s_3965 - name: (S)-Methylmalonate semialdehyde @@ -20174,6 +23012,7 @@ - annotation: !!omap - chebi: CHEBI:62413 - kegg.compound: C06002 + - sbo: SBO:0000247 - !!omap - id: s_3966 - name: Methylmalonate @@ -20183,6 +23022,7 @@ - annotation: !!omap - chebi: CHEBI:17453 - kegg.compound: C02170 + - sbo: SBO:0000247 - !!omap - id: s_3967 - name: Imidazole-4-acetaldehyde @@ -20192,6 +23032,7 @@ - annotation: !!omap - chebi: CHEBI:27398 - kegg.compound: C05130 + - sbo: SBO:0000247 - !!omap - id: s_3968 - name: Imidazole-4-acetate @@ -20201,6 +23042,7 @@ - annotation: !!omap - chebi: CHEBI:16974 - kegg.compound: C02835 + - sbo: SBO:0000247 - !!omap - id: s_3969 - name: 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al @@ -20210,6 +23052,7 @@ - annotation: !!omap - chebi: CHEBI:27428 - kegg.compound: C05445 + - sbo: SBO:0000247 - !!omap - id: s_3970 - name: 3alpha,7alpha-Dihydroxy-5beta-cholestanate @@ -20219,6 +23062,7 @@ - annotation: !!omap - chebi: CHEBI:16577 - kegg.compound: C04554 + - sbo: SBO:0000247 - !!omap - id: s_3971 - name: 5-Hydroxyindoleacetaldehyde @@ -20228,6 +23072,7 @@ - annotation: !!omap - chebi: CHEBI:50157 - kegg.compound: C05634 + - sbo: SBO:0000247 - !!omap - id: s_3972 - name: 5-Hydroxyindoleacetate @@ -20237,6 +23082,7 @@ - annotation: !!omap - chebi: CHEBI:27823 - kegg.compound: C05635 + - sbo: SBO:0000247 - !!omap - id: s_3973 - name: N4-Acetylaminobutanal @@ -20246,6 +23092,7 @@ - annotation: !!omap - chebi: CHEBI:7386 - kegg.compound: C05936 + - sbo: SBO:0000247 - !!omap - id: s_3974 - name: 4-Acetamidobutanoate @@ -20255,6 +23102,7 @@ - annotation: !!omap - chebi: CHEBI:11951 - kegg.compound: C02946 + - sbo: SBO:0000247 - !!omap - id: s_3975 - name: trans-3-Chloroallyl aldehyde @@ -20264,6 +23112,7 @@ - annotation: !!omap - chebi: CHEBI:28452 - kegg.compound: C06613 + - sbo: SBO:0000247 - !!omap - id: s_3976 - name: trans-3-Chloroacrylic acid @@ -20273,6 +23122,7 @@ - annotation: !!omap - chebi: CHEBI:19982 - kegg.compound: C06614 + - sbo: SBO:0000247 - !!omap - id: s_3977 - name: cis-3-Chloroallyl aldehyde @@ -20282,6 +23132,7 @@ - annotation: !!omap - chebi: CHEBI:80465 - kegg.compound: C16348 + - sbo: SBO:0000247 - !!omap - id: s_3978 - name: cis-3-Chloroacrylic acid @@ -20291,6 +23142,7 @@ - annotation: !!omap - chebi: CHEBI:27397 - kegg.compound: C06615 + - sbo: SBO:0000247 - !!omap - id: s_3979 - name: Chloroacetaldehyde @@ -20300,6 +23152,7 @@ - annotation: !!omap - chebi: CHEBI:27871 - kegg.compound: C06754 + - sbo: SBO:0000247 - !!omap - id: s_3980 - name: Chloroacetic acid @@ -20309,6 +23162,7 @@ - annotation: !!omap - chebi: CHEBI:27869 - kegg.compound: C06755 + - sbo: SBO:0000247 - !!omap - id: s_3981 - name: Perillyl aldehyde @@ -20318,6 +23172,7 @@ - annotation: !!omap - chebi: CHEBI:15421 - kegg.compound: C02576 + - sbo: SBO:0000247 - !!omap - id: s_3982 - name: Perillic acid @@ -20327,6 +23182,7 @@ - annotation: !!omap - chebi: CHEBI:36999 - kegg.compound: C11924 + - sbo: SBO:0000247 - !!omap - id: s_3983 - name: 2-trans,6-trans-Farnesal @@ -20336,6 +23192,7 @@ - annotation: !!omap - chebi: CHEBI:15894 - kegg.compound: C03461 + - sbo: SBO:0000247 - !!omap - id: s_3984 - name: Farnesoic acid @@ -20345,6 +23202,7 @@ - annotation: !!omap - chebi: CHEBI:84162 - kegg.compound: C16502 + - sbo: SBO:0000247 - !!omap - id: s_3985 - name: phospholipid @@ -20354,6 +23212,7 @@ - annotation: !!omap - chebi: CHEBI:16247 - kegg.compound: C00865 + - sbo: SBO:0000247 - !!omap - id: s_3986 - name: phospholipid @@ -20363,6 +23222,7 @@ - annotation: !!omap - chebi: CHEBI:16247 - kegg.compound: C00865 + - sbo: SBO:0000247 - !!omap - id: s_3987 - name: ADP @@ -20372,6 +23232,7 @@ - annotation: !!omap - chebi: CHEBI:456216 - kegg.compound: C00008 + - sbo: SBO:0000247 - !!omap - id: s_3988 - name: 1-oleoyl-sn-glycerol @@ -20380,6 +23241,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:75757 + - sbo: SBO:0000247 - !!omap - id: s_3989 - name: G10526 @@ -20388,6 +23250,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:132511 + - sbo: SBO:0000247 - !!omap - id: s_3990 - name: G00006 @@ -20396,6 +23259,7 @@ - charge: -2 - annotation: !!omap - chebi: CHEBI:132515 + - sbo: SBO:0000247 - !!omap - id: s_3991 - name: carnosine @@ -20405,6 +23269,7 @@ - annotation: !!omap - chebi: CHEBI:15727 - kegg.compound: C00386 + - sbo: SBO:0000247 - !!omap - id: s_3992 - name: anserine @@ -20414,30 +23279,39 @@ - annotation: !!omap - chebi: CHEBI:18323 - kegg.compound: C01262 + - sbo: SBO:0000247 - !!omap - id: s_3993 - name: G10595 - compartment: er - formula: C72H122N2O47P2R - charge: -2 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3994 - name: G10596 - compartment: er - formula: C78H132N2O52P2R - charge: -2 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3995 - name: G10597 - compartment: er - formula: C84H142N2O57P2R - charge: -2 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3996 - name: G00007 - compartment: er - formula: C90H152N2O62P2R - charge: -2 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_3997 - name: glycolate @@ -20447,6 +23321,7 @@ - annotation: !!omap - chebi: CHEBI:29805 - kegg.compound: C00160 + - sbo: SBO:0000247 - !!omap - id: s_3998 - name: sucrose @@ -20456,6 +23331,7 @@ - annotation: !!omap - chebi: CHEBI:17992 - kegg.compound: C00089 + - sbo: SBO:0000247 - !!omap - id: s_3999 - name: Isomaltose @@ -20465,6 +23341,7 @@ - annotation: !!omap - chebi: CHEBI:28189 - kegg.compound: C00252 + - sbo: SBO:0000247 - !!omap - id: s_4000 - name: Dextrin @@ -20474,22 +23351,29 @@ - annotation: !!omap - chebi: CHEBI:28675 - kegg.compound: C00721 + - sbo: SBO:0000247 - !!omap - id: s_4001 - name: G10598 - compartment: er - formula: C96H162N2O67P2R - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_4002 - name: G00149 - compartment: er - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_4003 - name: G00140 - compartment: er - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_4004 - name: Sulfur donor @@ -20498,6 +23382,7 @@ - annotation: !!omap - chebi: CHEBI:80867 - kegg.compound: C17023 + - sbo: SBO:0000247 - !!omap - id: s_4005 - name: 5'-Deoxyadenosine @@ -20507,21 +23392,28 @@ - annotation: !!omap - chebi: CHEBI:17319 - kegg.compound: C05198 + - sbo: SBO:0000247 - !!omap - id: s_4006 - name: S-sulfanyl-[L-cysteine desulfurase] - compartment: m - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_4007 - name: [disordered-form [Fe-S] cluster scaffold protein] - compartment: m - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_4008 - name: S-sulfanyl-[cysteine desulfurase]-[disordered-form scaffold protein] complex - compartment: m - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_4009 - name: hydrogen cyanide @@ -20531,6 +23423,7 @@ - annotation: !!omap - chebi: CHEBI:18407 - kegg.compound: C01326 + - sbo: SBO:0000247 - !!omap - id: s_4010 - name: thiosulfate @@ -20540,6 +23433,7 @@ - annotation: !!omap - chebi: CHEBI:33541 - kegg.compound: C00320 + - sbo: SBO:0000247 - !!omap - id: s_4011 - name: sulphite @@ -20549,6 +23443,7 @@ - annotation: !!omap - chebi: CHEBI:17359 - kegg.compound: C11481 + - sbo: SBO:0000247 - !!omap - id: s_4012 - name: thiocyanate @@ -20558,6 +23453,7 @@ - annotation: !!omap - chebi: CHEBI:29200 - kegg.compound: C01755 + - sbo: SBO:0000247 - !!omap - id: s_4013 - name: Mg(2+) @@ -20567,6 +23463,7 @@ - annotation: !!omap - chebi: CHEBI:18420 - kegg.compound: C00305 + - sbo: SBO:0000247 - !!omap - id: s_4014 - name: Mg(2+) @@ -20576,6 +23473,7 @@ - annotation: !!omap - chebi: CHEBI:18420 - kegg.compound: C00305 + - sbo: SBO:0000247 - !!omap - id: s_4015 - name: UDP-D-glucose @@ -20585,6 +23483,7 @@ - annotation: !!omap - chebi: CHEBI:58367 - kegg.compound: C00029 + - sbo: SBO:0000247 - !!omap - id: s_4016 - name: sulphate @@ -20594,6 +23493,7 @@ - annotation: !!omap - chebi: CHEBI:16189 - kegg.compound: C00059 + - sbo: SBO:0000247 - !!omap - id: s_4017 - name: N-Acetyl-D-glucosamine @@ -20603,6 +23503,7 @@ - annotation: !!omap - chebi: CHEBI:506227 - kegg.compound: C00140 + - sbo: SBO:0000247 - !!omap - id: s_4018 - name: polyphosphate @@ -20612,6 +23513,7 @@ - annotation: !!omap - chebi: CHEBI:16838 - kegg.compound: C00404 + - sbo: SBO:0000247 - !!omap - id: s_4019 - name: Cu2(+) @@ -20621,6 +23523,7 @@ - annotation: !!omap - chebi: CHEBI:29036 - kegg.compound: C00070 + - sbo: SBO:0000247 - !!omap - id: s_4020 - name: Cu2(+) @@ -20630,6 +23533,7 @@ - annotation: !!omap - chebi: CHEBI:29036 - kegg.compound: C00070 + - sbo: SBO:0000247 - !!omap - id: s_4021 - name: 2-Oxoglutaramate @@ -20639,6 +23543,7 @@ - annotation: !!omap - chebi: CHEBI:16769 - kegg.compound: C00940 + - sbo: SBO:0000247 - !!omap - id: s_4022 - name: porphyrin @@ -20648,6 +23553,7 @@ - annotation: !!omap - chebi: CHEBI:8337 - kegg.compound: C05113 + - sbo: SBO:0000247 - !!omap - id: s_4023 - name: porphyrin @@ -20657,12 +23563,15 @@ - annotation: !!omap - chebi: CHEBI:8337 - kegg.compound: C05113 + - sbo: SBO:0000247 - !!omap - id: s_4024 - name: Starch - compartment: c - formula: C12H22O11 - charge: 0 + - annotation: !!omap + - sbo: SBO:0000247 - !!omap - id: s_4025 - name: UDP-N-acetyl-alpha-D-glucosamine @@ -20672,6 +23581,7 @@ - annotation: !!omap - chebi: CHEBI:57705 - kegg.compound: C00043 + - sbo: SBO:0000247 - !!omap - id: s_4026 - name: Zn(2+) @@ -20681,6 +23591,7 @@ - annotation: !!omap - chebi: CHEBI:29105 - kegg.compound: C00038 + - sbo: SBO:0000247 - !!omap - id: s_4027 - name: Zn(2+) @@ -20690,6 +23601,7 @@ - annotation: !!omap - chebi: CHEBI:29105 - kegg.compound: C00038 + - sbo: SBO:0000247 - !!omap - id: s_4028 - name: RX @@ -20699,6 +23611,7 @@ - annotation: !!omap - chebi: CHEBI:17792 - kegg.compound: C01322 + - sbo: SBO:0000247 - !!omap - id: s_4029 - name: HX @@ -20708,6 +23621,7 @@ - annotation: !!omap - chebi: CHEBI:16042 - kegg.compound: C00462 + - sbo: SBO:0000247 - !!omap - id: s_4030 - name: R-S-glutathione @@ -20717,6 +23631,7 @@ - annotation: !!omap - chebi: CHEBI:17021 - kegg.compound: C02320 + - sbo: SBO:0000247 - !!omap - id: s_4031 - name: iron(3+) @@ -20726,6 +23641,7 @@ - annotation: !!omap - chebi: CHEBI:29034 - kegg.compound: C14819 + - sbo: SBO:0000247 - !!omap - id: s_4032 - name: [protein]-L-lysine @@ -20735,6 +23651,7 @@ - annotation: !!omap - chebi: CHEBI:29969 - kegg.compound: C02188 + - sbo: SBO:0000247 - !!omap - id: s_4033 - name: [protein]-N(6)-acetyl-L-lysine @@ -20743,6 +23660,7 @@ - charge: 0 - annotation: !!omap - chebi: CHEBI:61930 + - sbo: SBO:0000247 - !!omap - id: s_4034 - name: Ala-Gln @@ -20752,6 +23670,7 @@ - annotation: !!omap - chebi: CHEBI:73788 - metanetx.chemical: MNXM40495 + - sbo: SBO:0000247 - !!omap - id: s_4035 - name: Ala-Gln @@ -20761,6 +23680,7 @@ - annotation: !!omap - chebi: CHEBI:73788 - metanetx.chemical: MNXM40495 + - sbo: SBO:0000247 - !!omap - id: s_4036 - name: Ala-Gln @@ -20770,6 +23690,7 @@ - annotation: !!omap - chebi: CHEBI:73788 - metanetx.chemical: MNXM40495 + - sbo: SBO:0000247 - !!omap - id: s_4037 - name: Ala-Glu @@ -20780,6 +23701,7 @@ - chebi: CHEBI:61396 - kegg.compound: C20958 - metanetx.chemical: MNXM4026 + - sbo: SBO:0000247 - !!omap - id: s_4038 - name: Ala-Glu @@ -20790,6 +23712,7 @@ - chebi: CHEBI:61396 - kegg.compound: C20958 - metanetx.chemical: MNXM4026 + - sbo: SBO:0000247 - !!omap - id: s_4039 - name: Ala-Glu @@ -20800,6 +23723,7 @@ - chebi: CHEBI:61396 - kegg.compound: C20958 - metanetx.chemical: MNXM4026 + - sbo: SBO:0000247 - !!omap - id: s_4040 - name: Ala-Thr @@ -20809,6 +23733,7 @@ - annotation: !!omap - chebi: CHEBI:73762 - metanetx.chemical: MNXM40497 + - sbo: SBO:0000247 - !!omap - id: s_4041 - name: Ala-Thr @@ -20818,6 +23743,7 @@ - annotation: !!omap - chebi: CHEBI:73762 - metanetx.chemical: MNXM40497 + - sbo: SBO:0000247 - !!omap - id: s_4042 - name: Ala-Thr @@ -20827,6 +23753,7 @@ - annotation: !!omap - chebi: CHEBI:73762 - metanetx.chemical: MNXM40497 + - sbo: SBO:0000247 - !!omap - id: s_4043 - name: L-threonine @@ -20837,6 +23764,7 @@ - chebi: CHEBI:16857 - kegg.compound: C00188 - metanetx.chemical: MNXM142 + - sbo: SBO:0000247 - !!omap - id: s_4044 - name: thymidine 3'-monophosphate @@ -20846,6 +23774,7 @@ - annotation: !!omap - chebi: CHEBI:77843 - metanetx.chemical: MNXM87165 + - sbo: SBO:0000247 - !!omap - id: s_4045 - name: thymidine 3'-monophosphate @@ -20855,6 +23784,7 @@ - annotation: !!omap - chebi: CHEBI:77843 - metanetx.chemical: MNXM87165 + - sbo: SBO:0000247 - !!omap - id: s_4046 - name: thymidine 5'-monophosphate @@ -20864,6 +23794,7 @@ - annotation: !!omap - chebi: CHEBI:15245 - metanetx.chemical: MNXM87167 + - sbo: SBO:0000247 - !!omap - id: s_4047 - name: thymidine 5'-monophosphate @@ -20873,6 +23804,7 @@ - annotation: !!omap - chebi: CHEBI:15245 - metanetx.chemical: MNXM87167 + - sbo: SBO:0000247 - !!omap - id: s_4048 - name: glycerol 1-phosphate @@ -20883,6 +23815,7 @@ - chebi: CHEBI:231935 - kegg.compound: C03189 - metanetx.chemical: MNXM682 + - sbo: SBO:0000247 - !!omap - id: s_4049 - name: glycerol 1-phosphate @@ -20893,6 +23826,7 @@ - chebi: CHEBI:231935 - kegg.compound: C03189 - metanetx.chemical: MNXM682 + - sbo: SBO:0000247 - !!omap - id: s_4050 - name: Ala-His @@ -20902,6 +23836,7 @@ - annotation: !!omap - chebi: CHEBI:73771 - metanetx.chemical: MNXM40496 + - sbo: SBO:0000247 - !!omap - id: s_4051 - name: Ala-His @@ -20911,6 +23846,7 @@ - annotation: !!omap - chebi: CHEBI:73771 - metanetx.chemical: MNXM40496 + - sbo: SBO:0000247 - !!omap - id: s_4052 - name: Ala-His @@ -20920,6 +23856,7 @@ - annotation: !!omap - chebi: CHEBI:73771 - metanetx.chemical: MNXM40496 + - sbo: SBO:0000247 - !!omap - id: s_4053 - name: Gly-Asn @@ -20929,6 +23866,7 @@ - annotation: !!omap - chebi: CHEBI:73888 - metanetx.chemical: MNXM55268 + - sbo: SBO:0000247 - !!omap - id: s_4054 - name: Gly-Asn @@ -20938,6 +23876,7 @@ - annotation: !!omap - chebi: CHEBI:73888 - metanetx.chemical: MNXM55268 + - sbo: SBO:0000247 - !!omap - id: s_4055 - name: Gly-Asn @@ -20947,6 +23886,7 @@ - annotation: !!omap - chebi: CHEBI:73888 - metanetx.chemical: MNXM55268 + - sbo: SBO:0000247 - !!omap - id: s_4056 - name: Gly-Gln @@ -20956,6 +23896,7 @@ - annotation: !!omap - chebi: CHEBI:73898 - metanetx.chemical: MNXM55276 + - sbo: SBO:0000247 - !!omap - id: s_4057 - name: Gly-Gln @@ -20965,6 +23906,7 @@ - annotation: !!omap - chebi: CHEBI:73898 - metanetx.chemical: MNXM55276 + - sbo: SBO:0000247 - !!omap - id: s_4058 - name: Gly-Gln @@ -20974,6 +23916,7 @@ - annotation: !!omap - chebi: CHEBI:73898 - metanetx.chemical: MNXM55276 + - sbo: SBO:0000247 - !!omap - id: s_4059 - name: Gly-Glu @@ -20983,6 +23926,7 @@ - annotation: !!omap - chebi: CHEBI:73784 - metanetx.chemical: MNXM55454 + - sbo: SBO:0000247 - !!omap - id: s_4060 - name: Gly-Glu @@ -20992,6 +23936,7 @@ - annotation: !!omap - chebi: CHEBI:73784 - metanetx.chemical: MNXM55454 + - sbo: SBO:0000247 - !!omap - id: s_4061 - name: Gly-Glu @@ -21001,6 +23946,7 @@ - annotation: !!omap - chebi: CHEBI:73784 - metanetx.chemical: MNXM55454 + - sbo: SBO:0000247 - !!omap - id: s_4062 - name: glycerol 2-phosphate(2-) @@ -21011,6 +23957,7 @@ - chebi: CHEBI:58083 - kegg.compound: C02979 - metanetx.chemical: MNXM2527 + - sbo: SBO:0000247 - !!omap - id: s_4063 - name: glycerol 2-phosphate(2-) @@ -21021,6 +23968,7 @@ - chebi: CHEBI:58083 - kegg.compound: C02979 - metanetx.chemical: MNXM2527 + - sbo: SBO:0000247 - !!omap - id: s_4064 - name: O-phospho-L-threonine @@ -21031,6 +23979,7 @@ - chebi: CHEBI:58675 - kegg.compound: C12147 - metanetx.chemical: MNXM1492 + - sbo: SBO:0000247 - !!omap - id: s_4065 - name: O-phospho-L-threonine @@ -21041,6 +23990,7 @@ - chebi: CHEBI:58675 - kegg.compound: C12147 - metanetx.chemical: MNXM1492 + - sbo: SBO:0000247 - !!omap - id: s_4066 - name: guanosine 2'-monophosphate @@ -21050,6 +24000,7 @@ - annotation: !!omap - chebi: CHEBI:74604 - metanetx.chemical: MNXM18285 + - sbo: SBO:0000247 - !!omap - id: s_4067 - name: guanosine 2'-monophosphate @@ -21059,6 +24010,7 @@ - annotation: !!omap - chebi: CHEBI:74604 - metanetx.chemical: MNXM18285 + - sbo: SBO:0000247 - !!omap - id: s_4068 - name: 3'-GMP @@ -21069,6 +24021,7 @@ - chebi: CHEBI:60732 - kegg.compound: C06193 - metanetx.chemical: MNXM2183 + - sbo: SBO:0000247 - !!omap - id: s_4069 - name: 3'-GMP @@ -21079,6 +24032,7 @@ - chebi: CHEBI:60732 - kegg.compound: C06193 - metanetx.chemical: MNXM2183 + - sbo: SBO:0000247 - !!omap - id: s_4070 - name: 2-phosphoglycolate @@ -21089,6 +24043,7 @@ - chebi: CHEBI:58033 - kegg.compound: C00988 - metanetx.chemical: MNXM2074 + - sbo: SBO:0000247 - !!omap - id: s_4071 - name: 2-phosphoglycolate @@ -21099,6 +24054,7 @@ - chebi: CHEBI:58033 - kegg.compound: C00988 - metanetx.chemical: MNXM2074 + - sbo: SBO:0000247 - !!omap - id: s_4072 - name: cysteamine S-phosphate @@ -21108,6 +24064,7 @@ - annotation: !!omap - chebi: CHEBI:74631 - metanetx.chemical: MNXM48297 + - sbo: SBO:0000247 - !!omap - id: s_4073 - name: cysteamine @@ -21118,6 +24075,7 @@ - chebi: CHEBI:58029 - kegg.compound: C01678 - metanetx.chemical: MNXM1226 + - sbo: SBO:0000247 - !!omap - id: s_4074 - name: cysteamine @@ -21128,6 +24086,7 @@ - chebi: CHEBI:58029 - kegg.compound: C01678 - metanetx.chemical: MNXM1226 + - sbo: SBO:0000247 - !!omap - id: s_4075 - name: cysteamine S-phosphate @@ -21137,6 +24096,7 @@ - annotation: !!omap - chebi: CHEBI:74631 - metanetx.chemical: MNXM48297 + - sbo: SBO:0000247 - !!omap - id: s_4076 - name: hypotaurine @@ -21147,6 +24107,7 @@ - chebi: CHEBI:16668 - kegg.compound: C00519 - metanetx.chemical: MNXM726 + - sbo: SBO:0000247 - !!omap - id: s_4077 - name: O-phosphonatooxy-D-serine(2-) @@ -21157,6 +24118,7 @@ - chebi: CHEBI:58680 - kegg.compound: C02532 - metanetx.chemical: MNXM4752 + - sbo: SBO:0000247 - !!omap - id: s_4078 - name: O-phosphonatooxy-D-serine(2-) @@ -21167,6 +24129,7 @@ - chebi: CHEBI:58680 - kegg.compound: C02532 - metanetx.chemical: MNXM4752 + - sbo: SBO:0000247 - !!omap - id: s_4079 - name: 2-aminobutanoate @@ -21176,6 +24139,7 @@ - annotation: !!omap - chebi: CHEBI:35621 - metanetx.chemical: MNXM15850 + - sbo: SBO:0000247 - !!omap - id: s_4080 - name: 2-aminobutanoate @@ -21185,6 +24149,7 @@ - annotation: !!omap - chebi: CHEBI:35621 - metanetx.chemical: MNXM15850 + - sbo: SBO:0000247 - !!omap - id: s_4081 - name: uridine 2'-phosphate @@ -21195,6 +24160,7 @@ - chebi: CHEBI:77802 - kegg.compound: C03031 - metanetx.chemical: MNXM13238 + - sbo: SBO:0000247 - !!omap - id: s_4082 - name: uridine 2'-phosphate @@ -21205,6 +24171,7 @@ - chebi: CHEBI:77802 - kegg.compound: C03031 - metanetx.chemical: MNXM13238 + - sbo: SBO:0000247 - !!omap - id: s_4083 - name: 3'-UMP @@ -21215,6 +24182,7 @@ - chebi: CHEBI:60784 - kegg.compound: C01368 - metanetx.chemical: MNXM2184 + - sbo: SBO:0000247 - !!omap - id: s_4084 - name: 3'-UMP @@ -21225,6 +24193,7 @@ - chebi: CHEBI:60784 - kegg.compound: C01368 - metanetx.chemical: MNXM2184 + - sbo: SBO:0000247 - !!omap - id: s_4085 - name: Gly-Met @@ -21234,6 +24203,7 @@ - annotation: !!omap - chebi: CHEBI:74393 - metanetx.chemical: MNXM55287 + - sbo: SBO:0000247 - !!omap - id: s_4086 - name: Gly-Met @@ -21243,6 +24213,7 @@ - annotation: !!omap - chebi: CHEBI:74393 - metanetx.chemical: MNXM55287 + - sbo: SBO:0000247 - !!omap - id: s_4087 - name: Gly-Met @@ -21252,6 +24223,7 @@ - annotation: !!omap - chebi: CHEBI:74393 - metanetx.chemical: MNXM55287 + - sbo: SBO:0000247 - !!omap - id: s_4088 - name: N-phosphocreatine @@ -21261,6 +24233,7 @@ - annotation: !!omap - chebi: CHEBI:58092 - metanetx.chemical: MNXM819 + - sbo: SBO:0000247 - !!omap - id: s_4089 - name: creatinine @@ -21271,6 +24244,7 @@ - chebi: CHEBI:16737 - kegg.compound: C00791 - metanetx.chemical: MNXM1470 + - sbo: SBO:0000247 - !!omap - id: s_4090 - name: N-phosphocreatine @@ -21280,6 +24254,7 @@ - annotation: !!omap - chebi: CHEBI:58092 - metanetx.chemical: MNXM819 + - sbo: SBO:0000247 - !!omap - id: s_4091 - name: creatinine @@ -21290,6 +24265,7 @@ - chebi: CHEBI:16737 - kegg.compound: C00791 - metanetx.chemical: MNXM1470 + - sbo: SBO:0000247 - !!omap - id: s_4092 - name: N(omega)-phospho-L-arginine @@ -21300,6 +24276,7 @@ - chebi: CHEBI:58477 - kegg.compound: C05945 - metanetx.chemical: MNXM3663 + - sbo: SBO:0000247 - !!omap - id: s_4093 - name: N(omega)-phospho-L-arginine @@ -21310,6 +24287,7 @@ - chebi: CHEBI:58477 - kegg.compound: C05945 - metanetx.chemical: MNXM3663 + - sbo: SBO:0000247 - !!omap - id: s_4094 - name: 2',3'-cyclic GMP @@ -21320,6 +24298,7 @@ - chebi: CHEBI:60837 - kegg.compound: C06194 - metanetx.chemical: MNXM3149 + - sbo: SBO:0000247 - !!omap - id: s_4095 - name: 2',3'-cyclic GMP @@ -21330,6 +24309,7 @@ - chebi: CHEBI:60837 - kegg.compound: C06194 - metanetx.chemical: MNXM3149 + - sbo: SBO:0000247 - !!omap - id: s_4096 - name: O(4)-phospho-L-tyrosine @@ -21340,6 +24320,7 @@ - chebi: CHEBI:62338 - kegg.compound: C06501 - metanetx.chemical: MNXM3323 + - sbo: SBO:0000247 - !!omap - id: s_4097 - name: O(4)-phospho-L-tyrosine @@ -21350,6 +24331,7 @@ - chebi: CHEBI:62338 - kegg.compound: C06501 - metanetx.chemical: MNXM3323 + - sbo: SBO:0000247 - !!omap - id: s_4098 - name: triphosphate @@ -21360,6 +24342,7 @@ - chebi: CHEBI:18036 - kegg.compound: C00536 - metanetx.chemical: MNXM332 + - sbo: SBO:0000247 - !!omap - id: s_4099 - name: triphosphate @@ -21370,6 +24353,7 @@ - chebi: CHEBI:18036 - kegg.compound: C00536 - metanetx.chemical: MNXM332 + - sbo: SBO:0000247 - !!omap - id: s_4100 - name: cytidine 2'-phosphate @@ -21380,6 +24364,7 @@ - chebi: CHEBI:77766 - kegg.compound: C03104 - metanetx.chemical: MNXM11237 + - sbo: SBO:0000247 - !!omap - id: s_4101 - name: cytidine 2'-phosphate @@ -21390,6 +24375,7 @@ - chebi: CHEBI:77766 - kegg.compound: C03104 - metanetx.chemical: MNXM11237 + - sbo: SBO:0000247 - !!omap - id: s_4102 - name: 2',3'-cyclic UMP @@ -21400,6 +24386,7 @@ - chebi: CHEBI:60873 - kegg.compound: C02355 - metanetx.chemical: MNXM3150 + - sbo: SBO:0000247 - !!omap - id: s_4103 - name: 2',3'-cyclic UMP @@ -21410,6 +24397,7 @@ - chebi: CHEBI:60873 - kegg.compound: C02355 - metanetx.chemical: MNXM3150 + - sbo: SBO:0000247 - !!omap - id: s_4104 - name: 3-sulfino-L-alanine @@ -21420,6 +24408,7 @@ - chebi: CHEBI:61085 - kegg.compound: C00606 - metanetx.chemical: MNXM498 + - sbo: SBO:0000247 - !!omap - id: s_4105 - name: 3-sulfino-L-alanine @@ -21430,6 +24419,7 @@ - chebi: CHEBI:61085 - kegg.compound: C00606 - metanetx.chemical: MNXM498 + - sbo: SBO:0000247 - !!omap - id: s_4106 - name: 3'-AMP @@ -21440,6 +24430,7 @@ - chebi: CHEBI:60880 - kegg.compound: C01367 - metanetx.chemical: MNXM1985 + - sbo: SBO:0000247 - !!omap - id: s_4107 - name: 3'-AMP @@ -21450,6 +24441,7 @@ - chebi: CHEBI:60880 - kegg.compound: C01367 - metanetx.chemical: MNXM1985 + - sbo: SBO:0000247 - !!omap - id: s_4108 - name: 6-O-alpha-D-glucopyranosyl-D-fructofuranose @@ -21460,6 +24452,7 @@ - chebi: CHEBI:18394 - kegg.compound: C01742 - metanetx.chemical: MNXM3518 + - sbo: SBO:0000247 - !!omap - id: s_4109 - name: 6-O-alpha-D-glucopyranosyl-D-fructofuranose @@ -21470,6 +24463,7 @@ - chebi: CHEBI:18394 - kegg.compound: C01742 - metanetx.chemical: MNXM3518 + - sbo: SBO:0000247 - !!omap - id: s_4110 - name: N-acetyl-L-cysteine @@ -21480,6 +24474,7 @@ - chebi: CHEBI:78236 - kegg.compound: C06809 - metanetx.chemical: MNXM98606 + - sbo: SBO:0000247 - !!omap - id: s_4111 - name: N-acetyl-L-cysteine @@ -21490,6 +24485,7 @@ - chebi: CHEBI:78236 - kegg.compound: C06809 - metanetx.chemical: MNXM98606 + - sbo: SBO:0000247 - !!omap - id: s_4112 - name: tetrathionate @@ -21500,6 +24496,7 @@ - chebi: CHEBI:15226 - kegg.compound: C02084 - metanetx.chemical: MNXM1781 + - sbo: SBO:0000247 - !!omap - id: s_4113 - name: thiosulfate @@ -21510,6 +24507,7 @@ - chebi: CHEBI:33542 - kegg.compound: C00320 - metanetx.chemical: MNXM323 + - sbo: SBO:0000247 - !!omap - id: s_4114 - name: tetrathionate @@ -21520,6 +24518,7 @@ - chebi: CHEBI:15226 - kegg.compound: C02084 - metanetx.chemical: MNXM1781 + - sbo: SBO:0000247 - !!omap - id: s_4115 - name: 2-hydroxyethane-1-sulfonate @@ -21530,6 +24529,7 @@ - chebi: CHEBI:61904 - kegg.compound: C05123 - metanetx.chemical: MNXM1630 + - sbo: SBO:0000247 - !!omap - id: s_4116 - name: 2-hydroxyethane-1-sulfonate @@ -21540,6 +24540,7 @@ - chebi: CHEBI:61904 - kegg.compound: C05123 - metanetx.chemical: MNXM1630 + - sbo: SBO:0000247 - !!omap - id: s_4117 - name: 5-dehydro-D-gluconate @@ -21550,6 +24551,7 @@ - chebi: CHEBI:58143 - kegg.compound: C01062 - metanetx.chemical: MNXM963 + - sbo: SBO:0000247 - !!omap - id: s_4118 - name: 5-dehydro-D-gluconate @@ -21560,6 +24562,7 @@ - chebi: CHEBI:58143 - kegg.compound: C01062 - metanetx.chemical: MNXM963 + - sbo: SBO:0000247 - !!omap - id: s_4119 - name: Ala-Asp @@ -21569,6 +24572,7 @@ - annotation: !!omap - chebi: CHEBI:74363 - metanetx.chemical: MNXM40494 + - sbo: SBO:0000247 - !!omap - id: s_4120 - name: Ala-Asp @@ -21578,6 +24582,7 @@ - annotation: !!omap - chebi: CHEBI:74363 - metanetx.chemical: MNXM40494 + - sbo: SBO:0000247 - !!omap - id: s_4121 - name: Ala-Asp @@ -21587,6 +24592,7 @@ - annotation: !!omap - chebi: CHEBI:74363 - metanetx.chemical: MNXM40494 + - sbo: SBO:0000247 - !!omap - id: s_4122 - name: methyl alpha-D-glucopyranoside @@ -21596,6 +24602,7 @@ - annotation: !!omap - chebi: CHEBI:320061 - metanetx.chemical: MNXM61741 + - sbo: SBO:0000247 - !!omap - id: s_4123 - name: methanol @@ -21606,6 +24613,7 @@ - chebi: CHEBI:17790 - kegg.compound: C00132 - metanetx.chemical: MNXM157 + - sbo: SBO:0000247 - !!omap - id: s_4124 - name: methanol @@ -21616,6 +24624,7 @@ - chebi: CHEBI:17790 - kegg.compound: C00132 - metanetx.chemical: MNXM157 + - sbo: SBO:0000247 - !!omap - id: s_4125 - name: methyl alpha-D-glucopyranoside @@ -21625,6 +24634,7 @@ - annotation: !!omap - chebi: CHEBI:320061 - metanetx.chemical: MNXM61741 + - sbo: SBO:0000247 - !!omap - id: s_4126 - name: 2',3'-cyclic CMP @@ -21635,6 +24645,7 @@ - chebi: CHEBI:60877 - kegg.compound: C02354 - metanetx.chemical: MNXM3148 + - sbo: SBO:0000247 - !!omap - id: s_4127 - name: 2',3'-cyclic CMP @@ -21645,6 +24656,7 @@ - chebi: CHEBI:60877 - kegg.compound: C02354 - metanetx.chemical: MNXM3148 + - sbo: SBO:0000247 - !!omap - id: s_4128 - name: D-tagatose @@ -21655,6 +24667,7 @@ - chebi: CHEBI:4249 - kegg.compound: C00795 - metanetx.chemical: MNXM92401 + - sbo: SBO:0000247 - !!omap - id: s_4129 - name: D-tagatofuranose 6-phosphate @@ -21665,6 +24678,7 @@ - chebi: CHEBI:58695 - kegg.compound: C01097 - metanetx.chemical: MNXM795 + - sbo: SBO:0000247 - !!omap - id: s_4130 - name: D-tagatose @@ -21675,6 +24689,7 @@ - chebi: CHEBI:4249 - kegg.compound: C00795 - metanetx.chemical: MNXM92401 + - sbo: SBO:0000247 - !!omap - id: s_4131 - name: turanose @@ -21685,6 +24700,7 @@ - chebi: CHEBI:32528 - kegg.compound: C19636 - metanetx.chemical: MNXM161984 + - sbo: SBO:0000247 - !!omap - id: s_4132 - name: acetoacetate @@ -21695,6 +24711,7 @@ - chebi: CHEBI:13705 - kegg.compound: C00164 - metanetx.chemical: MNXM154 + - sbo: SBO:0000247 - !!omap - id: s_4133 - name: acetoacetate @@ -21705,6 +24722,7 @@ - chebi: CHEBI:13705 - kegg.compound: C00164 - metanetx.chemical: MNXM154 + - sbo: SBO:0000247 - !!omap - id: s_4134 - name: N(alpha)-acetyl-L-methionine @@ -21715,6 +24733,7 @@ - chebi: CHEBI:132957 - kegg.compound: C02712 - metanetx.chemical: MNXM7576 + - sbo: SBO:0000247 - !!omap - id: s_4135 - name: N(alpha)-acetyl-L-methionine @@ -21725,6 +24744,7 @@ - chebi: CHEBI:132957 - kegg.compound: C02712 - metanetx.chemical: MNXM7576 + - sbo: SBO:0000247 - !!omap - id: s_4136 - name: 3-oxalomalate(3-) @@ -21735,6 +24755,7 @@ - chebi: CHEBI:15593 - kegg.compound: C01990 - metanetx.chemical: MNXM3850 + - sbo: SBO:0000247 - !!omap - id: s_4137 - name: 3-oxalomalate(3-) @@ -21745,6 +24766,7 @@ - chebi: CHEBI:15593 - kegg.compound: C01990 - metanetx.chemical: MNXM3850 + - sbo: SBO:0000247 - !!omap - id: s_4138 - name: L-cysteate @@ -21755,6 +24777,7 @@ - chebi: CHEBI:58090 - kegg.compound: C00506 - metanetx.chemical: MNXM713 + - sbo: SBO:0000247 - !!omap - id: s_4139 - name: L-cysteate @@ -21765,6 +24788,7 @@ - chebi: CHEBI:58090 - kegg.compound: C00506 - metanetx.chemical: MNXM713 + - sbo: SBO:0000247 - !!omap - id: s_4140 - name: alpha-maltotriose @@ -21775,6 +24799,7 @@ - chebi: CHEBI:61993 - kegg.compound: C01835 - metanetx.chemical: MNXM468 + - sbo: SBO:0000247 - !!omap - id: s_4141 - name: 2-phospho-D-glyceric acid @@ -21785,6 +24810,7 @@ - chebi: CHEBI:58289 - kegg.compound: C00631 - metanetx.chemical: MNXM275 + - sbo: SBO:0000247 - !!omap - id: s_4142 - name: 3-phosphonato-D-glycerate(3-) @@ -21795,6 +24821,7 @@ - chebi: CHEBI:58272 - kegg.compound: C00197 - metanetx.chemical: MNXM126 + - sbo: SBO:0000247 - !!omap - id: s_4143 - name: Met-Ala @@ -21804,6 +24831,7 @@ - annotation: !!omap - chebi: CHEBI:73610 - metanetx.chemical: MNXM61647 + - sbo: SBO:0000247 - !!omap - id: s_4144 - name: Met-Ala @@ -21813,6 +24841,7 @@ - annotation: !!omap - chebi: CHEBI:73610 - metanetx.chemical: MNXM61647 + - sbo: SBO:0000247 - !!omap - id: s_4145 - name: D-glucose 1-phosphate @@ -21823,6 +24852,7 @@ - chebi: CHEBI:57629 - kegg.compound: C00103 - metanetx.chemical: MNXM89588 + - sbo: SBO:0000247 - !!omap - id: s_4146 - name: carbamoyl phosphate @@ -21833,6 +24863,7 @@ - chebi: CHEBI:58228 - kegg.compound: C00169 - metanetx.chemical: MNXM138 + - sbo: SBO:0000247 - !!omap - id: s_4147 - name: 3-phospho-serine @@ -21843,6 +24874,7 @@ - chebi: CHEBI:57524 - kegg.compound: C01005 - metanetx.chemical: MNXM379 + - sbo: SBO:0000247 - !!omap - id: s_4148 - name: GMP @@ -21853,6 +24885,7 @@ - chebi: CHEBI:58115 - kegg.compound: C00144 - metanetx.chemical: MNXM113 + - sbo: SBO:0000247 - !!omap - id: s_4149 - name: myo-inositol hexakisphosphate @@ -21863,6 +24896,7 @@ - chebi: CHEBI:58130 - kegg.compound: C01204 - metanetx.chemical: MNXM491 + - sbo: SBO:0000247 - !!omap - id: s_4150 - name: D-glucose 6-phosphate @@ -21873,6 +24907,7 @@ - chebi: CHEBI:61548 - kegg.compound: C00092 - metanetx.chemical: MNXM160 + - sbo: SBO:0000247 - !!omap - id: s_4151 - name: UMP @@ -21883,6 +24918,7 @@ - chebi: CHEBI:57865 - kegg.compound: C00105 - metanetx.chemical: MNXM80 + - sbo: SBO:0000247 - !!omap - id: s_4152 - name: phosphoenolpyruvate @@ -21893,6 +24929,7 @@ - chebi: CHEBI:58702 - kegg.compound: C00074 - metanetx.chemical: MNXM73 + - sbo: SBO:0000247 - !!omap - id: s_4153 - name: D-mannose 6-phosphate @@ -21903,6 +24940,7 @@ - chebi: CHEBI:58735 - kegg.compound: C00275 - metanetx.chemical: MNXM427 + - sbo: SBO:0000247 - !!omap - id: s_4154 - name: O-phosphoethanolamine @@ -21913,6 +24951,7 @@ - chebi: CHEBI:58190 - kegg.compound: C00346 - metanetx.chemical: MNXM187 + - sbo: SBO:0000247 - !!omap - id: s_4155 - name: 6-phospho-D-gluconate @@ -21923,6 +24962,7 @@ - chebi: CHEBI:58759 - kegg.compound: C00345 - metanetx.chemical: MNXM325 + - sbo: SBO:0000247 - !!omap - id: s_4156 - name: D-mannose 1-phosphate @@ -21933,6 +24973,7 @@ - chebi: CHEBI:58409 - kegg.compound: C00636 - metanetx.chemical: MNXM721 + - sbo: SBO:0000247 - !!omap - id: s_4157 - name: diphosphate @@ -21943,6 +24984,7 @@ - chebi: CHEBI:33019 - kegg.compound: C00013 - metanetx.chemical: MNXM11 + - sbo: SBO:0000247 - !!omap - id: s_4158 - name: choline phosphate @@ -21953,6 +24995,7 @@ - chebi: CHEBI:295975 - kegg.compound: C00588 - metanetx.chemical: MNXM229 + - sbo: SBO:0000247 - !!omap - id: s_4159 - name: thiosulfate @@ -21963,6 +25006,7 @@ - chebi: CHEBI:33542 - kegg.compound: C00320 - metanetx.chemical: MNXM323 + - sbo: SBO:0000247 - !!omap - id: s_4160 - name: AMP @@ -21973,6 +25017,7 @@ - chebi: CHEBI:456215 - kegg.compound: C00020 - metanetx.chemical: MNXM14 + - sbo: SBO:0000247 - !!omap - id: s_4161 - name: 2',3'-cyclic AMP @@ -21983,6 +25028,7 @@ - chebi: CHEBI:60879 - kegg.compound: C02353 - metanetx.chemical: MNXM2598 + - sbo: SBO:0000247 - !!omap - id: s_4162 - name: adenosine 2'-phosphate @@ -21993,6 +25039,7 @@ - chebi: CHEBI:77740 - kegg.compound: C00946 - metanetx.chemical: MNXM7028 + - sbo: SBO:0000247 - !!omap - id: s_4163 - name: CMP @@ -22003,6 +25050,7 @@ - chebi: CHEBI:60377 - kegg.compound: C00055 - metanetx.chemical: MNXM31 + - sbo: SBO:0000247 - !!omap - id: s_4164 - name: D-Glucosamine @@ -22013,6 +25061,7 @@ - chebi: CHEBI:58723 - kegg.compound: C00329 - metanetx.chemical: MNXM533 + - sbo: SBO:0000247 - !!omap - id: s_4165 - name: 2-deoxy-D-ribose @@ -22023,6 +25072,7 @@ - chebi: CHEBI:28816 - kegg.compound: C08347 - metanetx.chemical: MNXM2474 + - sbo: SBO:0000247 - !!omap - id: s_4166 - name: L-citrulline @@ -22033,6 +25083,7 @@ - chebi: CHEBI:16349 - kegg.compound: C00327 - metanetx.chemical: MNXM211 + - sbo: SBO:0000247 - !!omap - id: s_4167 - name: glycerone @@ -22043,6 +25094,7 @@ - chebi: CHEBI:16016 - kegg.compound: C00184 - metanetx.chemical: MNXM460 + - sbo: SBO:0000247 - !!omap - id: s_4168 - name: Ala-Leu @@ -22052,6 +25104,7 @@ - annotation: !!omap - chebi: CHEBI:73770 - metanetx.chemical: MNXM15786 + - sbo: SBO:0000247 - !!omap - id: s_4169 - name: Ala-Leu @@ -22061,6 +25114,7 @@ - annotation: !!omap - chebi: CHEBI:73770 - metanetx.chemical: MNXM15786 + - sbo: SBO:0000247 - !!omap - id: s_4170 - name: Ala-Gly @@ -22070,6 +25124,7 @@ - annotation: !!omap - chebi: CHEBI:73757 - metanetx.chemical: MNXM15783 + - sbo: SBO:0000247 - !!omap - id: s_4171 - name: Ala-Gly @@ -22079,6 +25134,7 @@ - annotation: !!omap - chebi: CHEBI:73757 - metanetx.chemical: MNXM15783 + - sbo: SBO:0000247 - !!omap - id: s_4172 - name: N-acetyl-L-glutamate @@ -22089,6 +25145,7 @@ - chebi: CHEBI:44337 - kegg.compound: C00624 - metanetx.chemical: MNXM730 + - sbo: SBO:0000247 - !!omap - id: s_4173 - name: N-acetyl-L-glutamate @@ -22099,6 +25156,7 @@ - chebi: CHEBI:44337 - kegg.compound: C00624 - metanetx.chemical: MNXM730 + - sbo: SBO:0000247 - !!omap - id: s_4174 - name: lipoamide @@ -22109,6 +25167,7 @@ - chebi: CHEBI:17460 - kegg.compound: C00248 - metanetx.chemical: MNXM1024 + - sbo: SBO:0000247 - !!omap - id: s_4175 - name: lipoamide @@ -22119,6 +25178,7 @@ - chebi: CHEBI:17460 - kegg.compound: C00248 - metanetx.chemical: MNXM1024 + - sbo: SBO:0000247 - !!omap - id: s_4176 - name: L-Methionine S-oxide @@ -22129,6 +25189,7 @@ - chebi: CHEBI:17016 - kegg.compound: C02989 - metanetx.chemical: MNXM2246 + - sbo: SBO:0000247 - !!omap - id: s_4177 - name: homogentisate @@ -22139,6 +25200,7 @@ - chebi: CHEBI:16169 - kegg.compound: C00544 - metanetx.chemical: MNXM345 + - sbo: SBO:0000247 - !!omap - id: s_4178 - name: 4-maleylacetoacetate @@ -22149,6 +25211,7 @@ - chebi: CHEBI:17105 - kegg.compound: C01036 - metanetx.chemical: MNXM691 + - sbo: SBO:0000247 - !!omap - id: s_4179 - name: 4-fumarylacetoacetate @@ -22159,6 +25222,7 @@ - chebi: CHEBI:18034 - kegg.compound: C01061 - metanetx.chemical: MNXM708 + - sbo: SBO:0000247 - !!omap - id: s_4180 - name: L-xylulose @@ -22169,6 +25233,7 @@ - chebi: CHEBI:17140 - kegg.compound: C00310 - metanetx.chemical: MNXM597 + - sbo: SBO:0000247 - !!omap - id: s_4181 - name: D-arabinitol @@ -22179,6 +25244,7 @@ - chebi: CHEBI:18333 - kegg.compound: C01904 - metanetx.chemical: MNXM1018 + - sbo: SBO:0000247 - reactions: - !!omap - id: r_0001 @@ -22199,6 +25265,7 @@ - 1.1.2.4 - 1.1.99.- - kegg.reaction: R00197 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0002 @@ -22219,6 +25286,7 @@ - 1.1.2.4 - 1.1.99.- - kegg.reaction: R00197 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0003 @@ -22236,6 +25304,7 @@ - annotation: !!omap - ec-code: 1.1.1.4 - kegg.reaction: R02946 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0004 @@ -22254,6 +25323,7 @@ - annotation: !!omap - ec-code: 1.1.2.3 - kegg.reaction: R00196 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0005 @@ -22273,6 +25343,7 @@ - ec-code: 2.4.1.34 - kegg.reaction: R03118 - pmid: 7649185 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0006 @@ -22287,6 +25358,7 @@ - gene_reaction_rule: YGR143W or YPR159W - annotation: !!omap - pmid: 8321211 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0007 @@ -22304,6 +25376,7 @@ - annotation: !!omap - ec-code: 5.3.1.16 - kegg.reaction: R04640 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0012 @@ -22324,6 +25397,7 @@ - annotation: !!omap - ec-code: 1.2.1.88 - pmid: 387737 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0013 @@ -22344,6 +25418,7 @@ - 1.13.11.54 - 3.1.3.77 - pmid: 14506228 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0014 @@ -22363,6 +25438,7 @@ - 3.5.4.26 - 5.4.99.28 - pmid: 9068650 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0015 @@ -22381,6 +25457,7 @@ - ec-code: 1.1.1.302 - kegg.reaction: R09376 - pmid: 9068650 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0016 @@ -22407,6 +25484,7 @@ - ec-code: 2.2.1.6 - kegg.reaction: R08648 - pmid: 8972574 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0017 @@ -22427,6 +25505,7 @@ - 2.7.6.3 - 4.1.2.25 - kegg.reaction: R03503 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0018 @@ -22460,6 +25539,7 @@ - pmid: - 10714900 - 19342587 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0019 @@ -22479,6 +25559,7 @@ - annotation: !!omap - ec-code: 1.1.1.169 - kegg.reaction: R02472 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0020 @@ -22500,6 +25581,7 @@ - annotation: !!omap - ec-code: 2.5.1.54 - kegg.reaction: R01826 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0021 @@ -22525,6 +25607,7 @@ - 2.7.-.- - kegg.reaction: R04983 - pmid: 15792955 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0022 @@ -22549,6 +25632,7 @@ - 2.7.-.- - kegg.reaction: R04982 - 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!!omap - id: r_0105 @@ -23921,6 +27073,7 @@ - annotation: !!omap - ec-code: 2.3.1.16 - kegg.reaction: R03858 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0106 @@ -23944,6 +27097,7 @@ - annotation: !!omap - ec-code: 2.3.1.16 - kegg.reaction: R03778 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0107 @@ -23967,6 +27121,7 @@ - annotation: !!omap - ec-code: 2.3.1.16 - kegg.reaction: R04742 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0108 @@ -23994,6 +27149,7 @@ - 6.4.1.2 - kegg.reaction: R00742 - pmid: 14761959 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0109 @@ -24019,6 +27175,7 @@ - annotation: !!omap - ec-code: 6.3.4.14 - kegg.reaction: R00742 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0111 @@ -24036,6 +27193,7 @@ - annotation: !!omap - ec-code: 3.1.2.1 - kegg.reaction: R00227 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0112 @@ -24062,6 +27220,7 @@ - ec-code: 6.2.1.1 - kegg.reaction: R00235 - pmid: 8910545 + - 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ec-code: 2.7.4.3 - kegg.reaction: R00127 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0149 @@ -24695,6 +27888,7 @@ - annotation: !!omap - ec-code: 2.7.4.10 - kegg.reaction: R00127 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0150 @@ -24714,6 +27908,7 @@ - sce01130 Biosynthesis of antibiotics - annotation: !!omap - ec-code: 2.7.4.10 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0151 @@ -24733,6 +27928,7 @@ - annotation: !!omap - ec-code: 4.3.2.2 - kegg.reaction: R04559 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0152 @@ -24752,6 +27948,7 @@ - annotation: !!omap - ec-code: 4.3.2.2 - kegg.reaction: R01083 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0153 @@ -24773,6 +27970,7 @@ - annotation: !!omap - ec-code: 6.3.4.4 - kegg.reaction: R01135 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0154 @@ -24793,6 +27991,7 @@ - ec-code: 2.7.1.25 - kegg.reaction: R00509 - pmid: 1654509 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0155 @@ -24808,6 +28007,7 @@ - annotation: !!omap - ec-code: 3.1.4.37 - pmid: 10734185 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0156 @@ -24831,6 +28031,7 @@ - annotation: !!omap - ec-code: 2.6.1.44 - kegg.reaction: R00369 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0157 @@ -24850,6 +28051,7 @@ - ec-code: 6.1.1.7 - kegg.reaction: R03038 - pmid: 7761427 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0158 @@ -24865,6 +28067,7 @@ - annotation: !!omap - ec-code: 2.3.1.84 - pmid: 12957907 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0159 @@ -24880,6 +28083,7 @@ - annotation: !!omap - ec-code: 2.3.1.84 - pmid: 12957907 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0160 @@ -24895,6 +28099,7 @@ - annotation: !!omap - ec-code: 2.3.1.84 - pmid: 12957907 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0161 @@ -24910,6 +28115,7 @@ - annotation: !!omap - ec-code: 2.3.1.84 - pmid: 12957907 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0162 @@ -24925,6 +28131,7 @@ - annotation: !!omap - ec-code: 2.3.1.84 - pmid: 12957907 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0163 @@ -24949,6 +28156,7 @@ - ec-code: 1.1.1.1 - kegg.reaction: R00754 - pmid: 12702265 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0164 @@ -24969,6 +28177,7 @@ - 1.1.1.21 - kegg.reaction: R01041 - pmid: 12210903 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0165 @@ -24993,6 +28202,7 @@ - ec-code: 1.1.1.1 - kegg.reaction: R00754 - pmid: 12499363 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0166 @@ -25020,6 +28230,7 @@ - 1.1.1.1 - 1.1.1.284 - pmid: 12702265 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0167 @@ -25043,6 +28254,7 @@ - annotation: !!omap - ec-code: 1.1.1.1 - pmid: 12499363 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0168 @@ -25070,6 +28282,7 @@ - pmid: - 12210903 - 12423374 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0169 @@ -25098,6 +28311,7 @@ - 1.1.1.284 - kegg.reaction: R02611 - pmid: 12702265 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0170 @@ -25122,6 +28336,7 @@ - ec-code: 1.1.1.1 - kegg.reaction: R02611 - pmid: 12499363 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0171 @@ -25147,6 +28362,7 @@ - pmid: - 11742541 - 12423374 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0172 @@ -25172,6 +28388,7 @@ - annotation: !!omap - ec-code: 1.2.1.3 - pmid: 12586697 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0173 @@ -25204,6 +28421,7 @@ - ec-code: 1.2.1.4 - kegg.reaction: R00711 - pmid: 15256563 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0174 @@ -25236,6 +28454,7 @@ - ec-code: 1.2.1.5 - kegg.reaction: R00710 - pmid: 15256563 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0175 @@ -25268,6 +28487,7 @@ - ec-code: 1.2.1.5 - kegg.reaction: R00711 - pmid: 15256563 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0176 @@ -25299,6 +28519,7 @@ - annotation: !!omap - ec-code: 1.2.1.5 - kegg.reaction: R02678 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0177 @@ -25329,6 +28550,7 @@ - sce01130 Biosynthesis of antibiotics - annotation: !!omap - ec-code: 1.2.1.4 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0178 @@ -25360,6 +28582,7 @@ - annotation: !!omap - ec-code: 1.2.1.5 - pmid: 9675847 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0179 @@ -25388,6 +28611,7 @@ - 1.1.1.284 - kegg.reaction: R05685 - pmid: 12702265 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0180 @@ -25412,6 +28636,7 @@ - ec-code: 1.1.1.1 - kegg.reaction: R05685 - pmid: 12499363 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0181 @@ -25438,6 +28663,7 @@ - pmid: - 11742541 - 12423374 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0182 @@ -25465,6 +28691,7 @@ - 1.1.1.1 - 1.1.1.284 - pmid: 12702265 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0183 @@ -25488,6 +28715,7 @@ - annotation: !!omap - ec-code: 1.1.1.1 - pmid: 12499363 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0184 @@ -25513,6 +28741,7 @@ - pmid: - 11742541 - 12423374 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0185 @@ -25539,6 +28768,7 @@ - ec-code: 1.2.1.3 - kegg.reaction: R02536 - pmid: 8801420 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0186 @@ -25567,6 +28797,7 @@ - 1.1.1.284 - kegg.reaction: R02679 - pmid: 12702265 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0187 @@ -25591,6 +28822,7 @@ - ec-code: 1.1.1.1 - kegg.reaction: R02679 - pmid: 12499363 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0188 @@ -25613,6 +28845,7 @@ - 3.1.3.54 - 3.1.7.6 - kegg.reaction: R04620 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0189 @@ -25629,6 +28862,7 @@ - annotation: !!omap - ec-code: 3.5.3.4 - pmid: 4604238 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0190 @@ -25646,6 +28880,7 @@ - ec-code: 3.5.2.5 - kegg.reaction: R02424 - pmid: 4604238 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0191 @@ -25666,6 +28901,7 @@ - ec-code: - 3.5.1.54 - 6.3.4.6 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0192 @@ -25690,6 +28926,7 @@ - 21623372 - 8631921 - 9020857 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0193 @@ -25704,6 +28941,7 @@ - subsystem: sce00500 Starch and sucrose metabolism - annotation: !!omap - ec-code: 3.2.1.28 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0194 @@ -25719,6 +28957,7 @@ - annotation: !!omap - ec-code: 3.2.1.28 - pmid: 8764988 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0195 @@ -25739,6 +28978,7 @@ - 3.1.3.12 - kegg.reaction: R00836 - pmid: 21623372 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0198 @@ -25758,6 +28998,7 @@ - 3.2.1.10 - 3.2.1.20 - kegg.reaction: R01555 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0199 @@ -25773,6 +29014,7 @@ - subsystem: sce00970 Aminoacyl-tRNA biosynthesis - annotation: !!omap - ec-code: 6.3.5.7 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0200 @@ -25788,6 +29030,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 3086094 + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_0201 @@ -25819,6 +29062,7 @@ - annotation: !!omap - ec-code: 1.2.1.5 - kegg.reaction: R02549 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0202 @@ -25839,6 +29083,7 @@ - annotation: !!omap - ec-code: 2.4.2.18 - kegg.reaction: R01073 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0203 @@ -25862,6 +29107,7 @@ - ec-code: 4.1.3.27 - kegg.reaction: R00986 - pmid: 8001582 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0204 @@ -25878,6 +29124,7 @@ - annotation: !!omap - ec-code: 3.6.1.29 - kegg.reaction: R00125 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0205 @@ -25897,6 +29144,7 @@ - 1.1.1.- - 1.1.1.21 - kegg.reaction: R01759 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0206 @@ -25917,6 +29165,7 @@ - sce01230 Biosynthesis of amino acids - annotation: !!omap - ec-code: 3.5.3.1 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0207 @@ -25937,6 +29186,7 @@ - annotation: !!omap - ec-code: 4.3.2.1 - kegg.reaction: R01086 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0208 @@ -25962,6 +29212,7 @@ - ec-code: 6.3.4.5 - kegg.reaction: R01954 - pmid: 35347 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0209 @@ -25980,6 +29231,7 @@ - annotation: !!omap - ec-code: 6.1.1.19 - kegg.reaction: R03646 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0210 @@ -25998,6 +29250,7 @@ - annotation: !!omap - ec-code: 6.1.1.19 - kegg.reaction: R03646 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0211 @@ -26022,6 +29275,7 @@ - ec-code: 6.3.5.4 - kegg.reaction: R00578 - pmid: 9881155 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0212 @@ -26041,6 +29295,7 @@ - ec-code: 6.1.1.22 - kegg.reaction: R03648 - pmid: 9605503 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0213 @@ -26060,6 +29315,7 @@ - ec-code: 6.1.1.22 - kegg.reaction: R03648 - pmid: 9605503 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0214 @@ -26081,6 +29337,7 @@ - 2.1.3.2 - 6.3.5.5 - kegg.reaction: R01397 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0215 @@ -26106,6 +29363,7 @@ - ec-code: 2.7.2.4 - kegg.reaction: R00480 - pmid: 9315655 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0216 @@ -26135,6 +29393,7 @@ - ec-code: 2.6.1.1 - kegg.reaction: R00355 - pmid: 1859361 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0217 @@ -26164,6 +29423,7 @@ - ec-code: 2.6.1.1 - kegg.reaction: R00355 - pmid: 1482685 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0218 @@ -26193,6 +29453,7 @@ - ec-code: 2.6.1.1 - kegg.reaction: R00355 - pmid: 9288922 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0219 @@ -26220,6 +29481,7 @@ - ec-code: 1.2.1.11 - kegg.reaction: R02291 - pmid: 2570346 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0220 @@ -26239,6 +29501,7 @@ - ec-code: 6.1.1.12 - kegg.reaction: R05577 - pmid: 3902099 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0221 @@ -26258,6 +29521,7 @@ - ec-code: 6.1.1.12 - kegg.reaction: R05577 - pmid: 2668951 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0222 @@ -26277,6 +29541,7 @@ - 2.7.7.5 - 2.7.7.53 - kegg.reaction: R00126 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0223 @@ -26297,6 +29562,7 @@ - ec-code: - 2.7.7.5 - 2.7.7.53 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0224 @@ -26317,6 +29583,7 @@ - ec-code: - 2.7.7.5 - 2.7.7.53 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0225 @@ -26336,6 +29603,7 @@ - annotation: !!omap - ec-code: 2.4.2.17 - kegg.reaction: R01071 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0226 @@ -26356,6 +29624,7 @@ - pmid: - 6223276 - 10576729 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_0227 @@ -26378,6 +29647,7 @@ - 3.6.1.5 - 3.6.3.6 - pmid: 10409709 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0228 @@ -26397,6 +29667,7 @@ - ec-code: 2.4.1.142 - kegg.reaction: R04502 - pmid: 6368538 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0229 @@ -26412,6 +29683,7 @@ - subsystem: sce00780 Biotin metabolism - annotation: !!omap - ec-code: 2.8.1.6 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0230 @@ -26435,6 +29707,7 @@ - 6.3.4.9 - kegg.reaction: R01074 - pmid: 9688262 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0231 @@ -26455,6 +29728,7 @@ - annotation: !!omap - ec-code: 1.3.1.70 - kegg.reaction: R05639 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0233 @@ -26475,6 +29749,7 @@ - sce01130 Biosynthesis of antibiotics - annotation: !!omap - ec-code: 1.14.19.41 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0234 @@ -26495,6 +29770,7 @@ - annotation: !!omap - ec-code: 1.1.1.170 - pmid: 22194828 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0235 @@ -26514,6 +29790,7 @@ - sce01130 Biosynthesis of antibiotics - annotation: !!omap - ec-code: 1.1.1.170 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0236 @@ -26533,6 +29810,7 @@ - annotation: !!omap - ec-code: 1.1.1.270 - kegg.reaction: R07495 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0237 @@ -26551,6 +29829,7 @@ - sce01130 Biosynthesis of antibiotics - annotation: !!omap - ec-code: 1.1.1.270 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0238 @@ -26571,6 +29850,7 @@ - sce01130 Biosynthesis of antibiotics - annotation: !!omap - ec-code: 1.14.13.72 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0239 @@ -26591,6 +29871,7 @@ - sce01130 Biosynthesis of antibiotics - annotation: !!omap - ec-code: 1.14.13.72 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0240 @@ -26612,6 +29893,7 @@ - annotation: !!omap - ec-code: 1.14.13.72 - pmid: 22194828 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0241 @@ -26633,6 +29915,7 @@ - annotation: !!omap - ec-code: 1.14.13.72 - kegg.reaction: R07509 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0242 @@ -26654,6 +29937,7 @@ - sce01130 Biosynthesis of antibiotics - annotation: !!omap - ec-code: 1.14.19.20 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0243 @@ -26670,6 +29954,7 @@ - annotation: !!omap - ec-code: 5.-.-.- - kegg.reaction: R07497 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0244 @@ -26689,6 +29974,7 @@ - annotation: !!omap - ec-code: 1.3.1.71 - kegg.reaction: R05641 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0249 @@ -26709,6 +29995,7 @@ - ec-code: 2.5.1.58 - kegg.reaction: R07273 - pmid: 1763050 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0250 @@ -26734,6 +30021,7 @@ - 2.1.3.2 - 6.3.5.5 - kegg.reaction: R00575 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0252 @@ -26750,6 +30038,7 @@ - annotation: !!omap - ec-code: 2.3.1.7 - pmid: 11329169 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0253 @@ -26765,6 +30054,7 @@ - subsystem: sce04146 Peroxisome - annotation: !!omap - ec-code: 2.3.1.7 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0254 @@ -26780,6 +30070,7 @@ - subsystem: sce04146 Peroxisome - annotation: !!omap - ec-code: 2.3.1.7 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0255 @@ -26803,6 +30094,7 @@ - annotation: !!omap - ec-code: 1.11.1.6 - pmid: 3536508 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0256 @@ -26826,6 +30118,7 @@ - annotation: !!omap - ec-code: 1.11.1.6 - pmid: 9931255 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0259 @@ -26847,6 +30140,7 @@ - pmid: - 18296751 - 9368039 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0260 @@ -26867,6 +30161,7 @@ - pmid: - 18296751 - 9368039 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0261 @@ -26888,6 +30183,7 @@ - pmid: - 18296751 - 9368039 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0262 @@ -26908,6 +30204,7 @@ - pmid: - 18296751 - 9368039 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0263 @@ -26928,6 +30225,7 @@ - 11387200 - 15692566 - 18296751 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0264 @@ -26949,6 +30247,7 @@ - 11387200 - 15692566 - 18296751 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0265 @@ -26969,6 +30268,7 @@ - 11387200 - 15692566 - 18296751 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0266 @@ -26990,6 +30290,7 @@ - 11387200 - 15692566 - 18296751 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0267 @@ -27010,6 +30311,7 @@ - pmid: - 18296751 - 9368039 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0268 @@ -27030,6 +30332,7 @@ - pmid: - 18296751 - 9368039 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0269 @@ -27050,6 +30353,7 @@ - pmid: - 18296751 - 9368039 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0270 @@ -27070,6 +30374,7 @@ - pmid: - 18296751 - 9368039 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0271 @@ -27087,6 +30392,7 @@ - annotation: !!omap - ec-code: 3.5.1.41 - kegg.reaction: R02333 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0272 @@ -27104,6 +30410,7 @@ - ec-code: 2.4.1.16 - kegg.reaction: R02335 - pmid: 16408321 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0273 @@ -27122,6 +30429,7 @@ - ec-code: 2.7.1.32 - kegg.reaction: R01021 - pmid: 10329685 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0274 @@ -27141,6 +30449,7 @@ - annotation: !!omap - ec-code: 2.7.7.15 - kegg.reaction: R01890 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0278 @@ -27160,6 +30469,7 @@ - ec-code: 5.4.99.5 - kegg.reaction: R01715 - pmid: 3027508 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0279 @@ -27180,6 +30490,7 @@ - ec-code: 4.2.3.5 - kegg.reaction: R01714 - pmid: 8971708 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0280 @@ -27203,6 +30514,7 @@ - ec-code: 4.2.1.3 - kegg.reaction: R01900 - pmid: 21623372 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0281 @@ -27222,6 +30534,7 @@ - ec-code: 2.5.1.87 - kegg.reaction: R02061 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0282 @@ -27241,6 +30554,7 @@ - ec-code: 2.5.1.87 - kegg.reaction: R07475 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0283 @@ -27260,6 +30574,7 @@ - ec-code: 2.5.1.87 - kegg.reaction: R05613 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0284 @@ -27279,6 +30594,7 @@ - ec-code: 2.5.1.87 - kegg.reaction: R05612 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0285 @@ -27298,6 +30614,7 @@ - ec-code: 2.5.1.87 - kegg.reaction: R05611 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0286 @@ -27317,6 +30634,7 @@ - ec-code: 2.5.1.87 - kegg.reaction: R07267 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0287 @@ -27336,6 +30654,7 @@ - ec-code: 2.5.1.87 - kegg.reaction: R08747 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0288 @@ -27354,6 +30673,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0289 @@ -27372,6 +30692,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0290 @@ -27390,6 +30711,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0291 @@ -27408,6 +30730,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0292 @@ -27426,6 +30749,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0293 @@ -27444,6 +30768,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0294 @@ -27462,6 +30787,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0295 @@ -27480,6 +30806,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0296 @@ -27498,6 +30825,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0297 @@ -27516,6 +30844,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0298 @@ -27534,6 +30863,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0299 @@ -27552,6 +30882,7 @@ - annotation: !!omap - ec-code: 2.5.1.87 - pmid: 12702274 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0300 @@ -27577,6 +30908,7 @@ - annotation: !!omap - ec-code: 2.3.3.1 - pmid: 9140965 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0301 @@ -27602,6 +30934,7 @@ - annotation: !!omap - ec-code: 2.3.3.16 - pmid: 10587442 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0302 @@ -27625,6 +30958,7 @@ - ec-code: 4.2.1.3 - kegg.reaction: R01325 - pmid: 21623372 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0303 @@ -27648,6 +30982,7 @@ - ec-code: 4.2.1.3 - kegg.reaction: R01325 - pmid: 15975908 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0304 @@ -27668,6 +31003,7 @@ - annotation: !!omap - ec-code: 1.3.3.3 - kegg.reaction: R03220 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0306 @@ -27689,6 +31025,7 @@ - annotation: !!omap - ec-code: 6.3.4.2 - kegg.reaction: R00573 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0307 @@ -27707,6 +31044,7 @@ - subsystem: sce00240 Pyrimidine metabolism - annotation: !!omap - ec-code: 6.3.4.2 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0308 @@ -27728,6 +31066,7 @@ - annotation: !!omap - ec-code: 4.4.1.8 - pmid: 10922376 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0309 @@ -27749,6 +31088,7 @@ - ec-code: 4.2.1.22 - kegg.reaction: R01290 - pmid: 10766767 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0310 @@ -27771,6 +31111,7 @@ - annotation: !!omap - ec-code: 4.4.1.1 - pmid: 1577698 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0311 @@ -27795,6 +31136,7 @@ - ec-code: 2.5.1.48 - kegg.reaction: R03217 - pmid: 10821189 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0312 @@ -27823,6 +31165,7 @@ - pmid: - 21623372 - 7765825 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0313 @@ -27842,6 +31185,7 @@ - ec-code: 6.1.1.16 - kegg.reaction: R03650 - pmid: 9523015 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0314 @@ -27858,6 +31202,7 @@ - subsystem: sce00240 Pyrimidine metabolism - annotation: !!omap - ec-code: 3.5.4.5 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0315 @@ -27875,6 +31220,7 @@ - annotation: !!omap - ec-code: 2.7.1.48 - kegg.reaction: R00517 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0317 @@ -27901,6 +31247,7 @@ - 1.6.2.4 - kegg.reaction: R05640 - pmid: 10622712 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0318 @@ -27919,6 +31266,7 @@ - sce00330 Arginine and proline metabolism - annotation: !!omap - ec-code: 3.5.4.1 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0319 @@ -27935,6 +31283,7 @@ - ec-code: 1.1.3.37 - kegg.reaction: R02715 - pmid: 10508108 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0320 @@ -27952,6 +31301,7 @@ - ec-code: 1.1.1.116 - kegg.reaction: R01574 - pmid: 17097644 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0321 @@ -27968,6 +31318,7 @@ - annotation: !!omap - ec-code: 1.1.1.117 - kegg.reaction: R01575 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0322 @@ -27991,6 +31342,7 @@ - annotation: !!omap - ec-code: 4.1.2.13 - kegg.reaction: R02568 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0323 @@ -28010,6 +31362,7 @@ - annotation: !!omap - ec-code: 1.1.1.14 - kegg.reaction: R00875 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0326 @@ -28026,6 +31379,7 @@ - subsystem: sce00240 Pyrimidine metabolism - annotation: !!omap - ec-code: 3.5.4.12 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0327 @@ -28042,6 +31396,7 @@ - subsystem: sce00240 Pyrimidine metabolism - annotation: !!omap - ec-code: 3.5.4.12 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0328 @@ -28058,6 +31413,7 @@ - subsystem: sce00230 Purine metabolism - annotation: !!omap - ec-code: 3.5.4.2 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0329 @@ -28074,6 +31430,7 @@ - subsystem: sce00240 Pyrimidine metabolism - annotation: !!omap - ec-code: 3.5.4.5 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0330 @@ -28090,6 +31447,7 @@ - annotation: !!omap - ec-code: 2.7.4.8 - kegg.reaction: R02090 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0331 @@ -28106,6 +31464,7 @@ - gene_reaction_rule: YHR068W - annotation: !!omap - ec-code: 2.5.1.46 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0332 @@ -28123,6 +31482,7 @@ - annotation: !!omap - ec-code: 2.7.1.15 - kegg.reaction: R02750 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0334 @@ -28140,6 +31500,7 @@ - annotation: !!omap - ec-code: 2.7.1.24 - kegg.reaction: R00130 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0335 @@ -28159,6 +31520,7 @@ - annotation: !!omap - ec-code: 6.3.3.3 - kegg.reaction: R03182 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0340 @@ -28176,6 +31538,7 @@ - pmid: - 10900202 - 18296751 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0341 @@ -28193,6 +31556,7 @@ - pmid: - 10900202 - 18296751 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0342 @@ -28210,6 +31574,7 @@ - pmid: - 10900202 - 18296751 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0343 @@ -28227,6 +31592,7 @@ - pmid: - 10900202 - 18296751 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0344 @@ -28246,6 +31612,7 @@ - annotation: !!omap - ec-code: 1.5.1.3 - kegg.reaction: R00939 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0345 @@ -28265,6 +31632,7 @@ - annotation: !!omap - ec-code: 1.5.1.3 - kegg.reaction: R00939 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0346 @@ -28285,6 +31653,7 @@ - ec-code: 6.3.2.12 - kegg.reaction: R02237 - pmid: 11731153 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0347 @@ -28303,6 +31672,7 @@ - 2.7.6.3 - 4.1.2.25 - kegg.reaction: R03504 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0348 @@ -28318,6 +31688,7 @@ - annotation: !!omap - ec-code: 3.6.-.- - kegg.reaction: R04621 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0349 @@ -28335,6 +31706,7 @@ - ec-code: 3.5.2.3 - kegg.reaction: R01993 - pmid: 2897615 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0350 @@ -28354,6 +31726,7 @@ - 2.7.6.3 - 4.1.2.25 - kegg.reaction: R03066 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0351 @@ -28373,6 +31746,7 @@ - 2.7.6.3 - 4.1.2.25 - kegg.reaction: R03067 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0352 @@ -28395,6 +31769,7 @@ - ec-code: 4.2.1.9 - kegg.reaction: R04441 - pmid: 14576278 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0353 @@ -28417,6 +31792,7 @@ - ec-code: 4.2.1.9 - kegg.reaction: R05070 - pmid: 14576278 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0354 @@ -28439,6 +31815,7 @@ - 2.7.1.28 - 2.7.1.29 - kegg.reaction: R01011 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0355 @@ -28460,6 +31837,7 @@ - 2.5.1.1 - 2.5.1.10 - kegg.reaction: R01658 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0356 @@ -28483,6 +31861,7 @@ - ec-code: 5.4.2.11 - kegg.reaction: R01662 - pmid: 6313356 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0357 @@ -28501,6 +31880,7 @@ - 3.6.1.52 - 3.6.1.60 - pmid: 10419486 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0358 @@ -28522,6 +31902,7 @@ - annotation: !!omap - ec-code: 2.7.4.21 - pmid: 11956213 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0359 @@ -28539,6 +31920,7 @@ - ec-code: 2.1.1.314 - kegg.reaction: R04481 - pmid: 1508200 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0360 @@ -28556,6 +31938,7 @@ - annotation: !!omap - ec-code: 2.7.1.108 - kegg.reaction: R01018 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0361 @@ -28572,6 +31955,7 @@ - annotation: !!omap - ec-code: 2.4.1.83 - kegg.reaction: R01009 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0362 @@ -28589,6 +31973,7 @@ - sce00515 Mannose type O-glycan biosynthesis - annotation: !!omap - ec-code: 2.4.1.109 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0363 @@ -28605,6 +31990,7 @@ - annotation: !!omap - ec-code: 2.7.4.9 - kegg.reaction: R02094 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0364 @@ -28622,6 +32008,7 @@ - annotation: !!omap - ec-code: 3.6.1.23 - kegg.reaction: R02100 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0365 @@ -28637,6 +32024,7 @@ - annotation: !!omap - ec-code: 3.2.1.15 - pmid: 10028181 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0366 @@ -28660,6 +32048,7 @@ - ec-code: 4.2.1.11 - kegg.reaction: R00658 - pmid: 7520111 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0368 @@ -28680,6 +32069,7 @@ - 2.7.1.82 - kegg.reaction: R01468 - pmid: 9506987 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0369 @@ -28696,6 +32086,7 @@ - annotation: !!omap - ec-code: 3.1.-.- - pmid: 10855721 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0370 @@ -28714,6 +32105,7 @@ - 3.2.1.6 - kegg.reaction: R00308 - pmid: 8458852 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0373 @@ -28738,6 +32130,7 @@ - 2.5.1.29 - kegg.reaction: R02061 - pmid: 7665600 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_0399 @@ -28759,6 +32152,7 @@ - sce04146 Peroxisome - annotation: !!omap - ec-code: 6.2.1.3 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0400 @@ -28780,6 +32174,7 @@ - sce04146 Peroxisome - annotation: !!omap - ec-code: 6.2.1.3 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0402 @@ -28802,6 +32197,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - kegg.reaction: R01280 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0410 @@ -28823,6 +32219,7 @@ - sce04146 Peroxisome - annotation: !!omap - ec-code: 6.2.1.3 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0412 @@ -28844,6 +32241,7 @@ - sce04146 Peroxisome - annotation: !!omap - ec-code: 6.2.1.3 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0436 @@ -28862,6 +32260,7 @@ - annotation: !!omap - ec-code: 4.99.1.1 - kegg.reaction: R00310 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_0437 @@ -28878,6 +32277,7 @@ - annotation: !!omap - ec-code: 1.11.1.5 - kegg.reaction: R00017 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - 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!!omap - id: r_1036 @@ -38130,6 +41991,7 @@ - 2.5.1.3 - 2.7.1.50 - kegg.reaction: R03223 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1037 @@ -38145,6 +42007,7 @@ - annotation: !!omap - ec-code: 1.11.1.15 - pmid: 12730197 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1038 @@ -38162,6 +42025,7 @@ - annotation: !!omap - ec-code: 1.8.1.9 - kegg.reaction: R02016 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1039 @@ -38184,6 +42048,7 @@ - 1.8.1.9 - kegg.reaction: R02016 - pmid: 15701801 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1040 @@ -38204,6 +42069,7 @@ - ec-code: 4.1.2.48 - kegg.reaction: R00751 - pmid: 9151955 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1041 @@ -38225,6 +42091,7 @@ - ec-code: 4.2.3.1 - kegg.reaction: R01466 - pmid: 8082795 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1042 @@ -38244,6 +42111,7 @@ - ec-code: 6.1.1.3 - kegg.reaction: R03663 - pmid: 2995918 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1043 @@ -38263,6 +42131,7 @@ - ec-code: 6.1.1.3 - kegg.reaction: R03663 - pmid: 2999113 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1045 @@ -38281,6 +42150,7 @@ - annotation: !!omap - ec-code: 2.1.1.45 - kegg.reaction: R02101 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1046 @@ -38297,6 +42167,7 @@ - ec-code: 2.1.1.145 - kegg.reaction: R05763 - pmid: 15147181 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1047 @@ -38316,6 +42187,7 @@ - ec-code: 2.5.1.- - kegg.reaction: R05613 - pmid: 2198286 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1048 @@ -38337,6 +42209,7 @@ - annotation: !!omap - ec-code: 2.2.1.2 - pmid: 8300619 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1049 @@ -38358,6 +42231,7 @@ - annotation: !!omap - ec-code: 2.2.1.1 - pmid: 8268320 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1050 @@ -38378,6 +42252,7 @@ - sce01230 Biosynthesis of amino acids - annotation: !!omap - ec-code: 2.2.1.1 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1051 @@ -38397,6 +42272,7 @@ - 3.1.3.12 - kegg.reaction: R02778 - pmid: 21623372 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1054 @@ -38419,6 +42295,7 @@ - annotation: !!omap - ec-code: 5.3.1.1 - pmid: 6759603 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1055 @@ -38441,6 +42318,7 @@ - annotation: !!omap - ec-code: 4.2.1.20 - pmid: 6342605 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1056 @@ -38473,6 +42351,7 @@ - pmid: - 9491082 - 9491083 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1057 @@ -38492,6 +42371,7 @@ - ec-code: 6.1.1.2 - kegg.reaction: R03664 - pmid: 9046085 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1058 @@ -38511,6 +42391,7 @@ - ec-code: 6.1.1.2 - kegg.reaction: R03664 - pmid: 2999114 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1063 @@ -38543,6 +42424,7 @@ - pmid: - 9491082 - 9491083 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1065 @@ -38571,6 +42453,7 @@ - annotation: !!omap - ec-code: 2.6.1.1 - kegg.reaction: R00734 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1066 @@ -38590,6 +42473,7 @@ - ec-code: 6.1.1.1 - kegg.reaction: R02918 - pmid: 8509419 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1067 @@ -38609,6 +42493,7 @@ - ec-code: 6.1.1.1 - kegg.reaction: R02918 - pmid: 3315228 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1068 @@ -38625,6 +42510,7 @@ - annotation: !!omap - ec-code: 2.4.1.173 - pmid: 10224056 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1069 @@ -38645,6 +42531,7 @@ - ec-code: 2.7.7.23 - kegg.reaction: R00416 - pmid: 16408321 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1070 @@ -38666,6 +42553,7 @@ - ec-code: - 5.1.3.2 - 5.1.3.3 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1071 @@ -38684,6 +42572,7 @@ - annotation: !!omap - ec-code: 2.7.7.12 - kegg.reaction: R00955 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1072 @@ -38700,6 +42589,7 @@ - annotation: !!omap - ec-code: 2.7.4.14 - kegg.reaction: R00158 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1073 @@ -38716,6 +42606,7 @@ - annotation: !!omap - ec-code: 2.7.4.14 - kegg.reaction: R00158 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1074 @@ -38732,6 +42623,7 @@ - annotation: !!omap - ec-code: 2.4.2.9 - kegg.reaction: R00966 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1075 @@ -38755,6 +42647,7 @@ - 3.5.1.54 - 6.3.4.6 - kegg.reaction: R00774 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1076 @@ -38773,6 +42666,7 @@ - annotation: !!omap - ec-code: 4.3.2.3 - pmid: 1776360 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1077 @@ -38790,6 +42684,7 @@ - annotation: !!omap - ec-code: 2.7.1.48 - kegg.reaction: R00964 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1078 @@ -38807,6 +42702,7 @@ - annotation: !!omap - ec-code: 2.7.1.48 - kegg.reaction: R00968 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1079 @@ -38823,6 +42719,7 @@ - annotation: !!omap - ec-code: 2.7.4.14 - kegg.reaction: R02098 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1080 @@ -38839,6 +42736,7 @@ - annotation: !!omap - ec-code: 2.7.4.14 - kegg.reaction: R02098 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1081 @@ -38857,6 +42755,7 @@ - annotation: !!omap - ec-code: 4.1.1.37 - kegg.reaction: R03197 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1082 @@ -38876,6 +42775,7 @@ - annotation: !!omap - ec-code: 2.1.1.107 - kegg.reaction: R03194 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1083 @@ -38893,6 +42793,7 @@ - annotation: !!omap - ec-code: 4.2.1.75 - kegg.reaction: R03165 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1084 @@ -38916,6 +42817,7 @@ - ec-code: 2.7.7.9 - kegg.reaction: R00289 - pmid: 7588797 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1085 @@ -38940,6 +42842,7 @@ - pmid: - 11278748 - 11836511 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1086 @@ -38964,6 +42867,7 @@ - pmid: - 11278748 - 11836511 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1087 @@ -38989,6 +42893,7 @@ - ec-code: 2.6.1.42 - kegg.reaction: R01214 - pmid: 9748245 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1088 @@ -39014,6 +42919,7 @@ - ec-code: 2.6.1.42 - kegg.reaction: R01214 - pmid: 9748245 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1089 @@ -39033,6 +42939,7 @@ - ec-code: 6.1.1.9 - kegg.reaction: R03665 - pmid: 3294828 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1090 @@ -39052,6 +42959,7 @@ - ec-code: 6.1.1.9 - kegg.reaction: R03665 - pmid: 3294828 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1091 @@ -39067,6 +42975,7 @@ - annotation: !!omap - ec-code: 2.4.2.- - kegg.reaction: R02142 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1092 @@ -39084,6 +42993,7 @@ - annotation: !!omap - ec-code: 1.1.1.9 - kegg.reaction: R01896 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1093 @@ -39103,6 +43013,7 @@ - 1.1.1.- - 1.1.1.21 - kegg.reaction: R01431 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1094 @@ -39120,6 +43031,7 @@ - annotation: !!omap - ec-code: 2.7.1.17 - kegg.reaction: R01639 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1095 @@ -39138,6 +43050,7 @@ - 5.4.99.25 - 5.4.99.44 - 5.4.99.45 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1096 @@ -39149,6 +43062,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 15215118 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1097 @@ -39160,6 +43074,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 10938079 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1098 @@ -39171,6 +43086,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 10653746 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1099 @@ -39187,6 +43103,7 @@ - pmid: - 16844075 - 11013234 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1100 @@ -39198,6 +43115,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 11583838 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1101 @@ -39210,6 +43128,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YDL210W or YOR348C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1102 @@ -39222,6 +43142,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YDL210W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1103 @@ -39233,6 +43155,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 8573145 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1104 @@ -39247,6 +43170,7 @@ - gene_reaction_rule: YNR056C - annotation: !!omap - pmid: 10333520 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1106 @@ -39259,6 +43183,7 @@ - gene_reaction_rule: YCR010C - annotation: !!omap - pmid: 14968426 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1107 @@ -39270,6 +43195,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 10653746 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1108 @@ -39282,6 +43208,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YER056C or YER060W or YER060W-A or YGL186C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1109 @@ -39296,6 +43224,7 @@ - gene_reaction_rule: YAL022C - annotation: !!omap - pmid: 10827169 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1110 @@ -39313,6 +43242,7 @@ - 22672422 - 7003152 - 14998997 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1111 @@ -39327,6 +43257,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YPR128C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1112 @@ -39341,6 +43273,7 @@ - gene_reaction_rule: YMR241W - annotation: !!omap - pmid: 20371607 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1113 @@ -39351,6 +43284,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YJR152W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1114 @@ -39361,6 +43296,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YIR028W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1115 @@ -39373,6 +43310,7 @@ - gene_reaction_rule: YDR384C or YGR121C or YNL142W or YPR138C - annotation: !!omap - pmid: 12966084 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1116 @@ -39387,6 +43325,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YPR128C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1118 @@ -39401,6 +43341,7 @@ - gene_reaction_rule: YPR021C - annotation: !!omap - pmid: 14622413 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1119 @@ -39413,6 +43354,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YGR065C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1120 @@ -39425,6 +43368,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YOR100C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1121 @@ -39436,6 +43381,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 12484746 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1122 @@ -39447,6 +43393,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 12484746 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1123 @@ -39458,6 +43405,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 12484746 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1124 @@ -39469,6 +43417,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 12484746 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1125 @@ -39481,6 +43430,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YGL077C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1126 @@ -39493,6 +43444,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR291C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1127 @@ -39505,6 +43458,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR291C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1128 @@ -39517,6 +43472,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR291C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1129 @@ -39529,6 +43486,7 @@ - gene_reaction_rule: YHR002W - annotation: !!omap - pmid: 11158296 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1130 @@ -39545,6 +43503,7 @@ - gene_reaction_rule: YBR192W - annotation: !!omap - pmid: 16844075 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1131 @@ -39561,6 +43520,7 @@ - gene_reaction_rule: YBR192W - annotation: !!omap - pmid: 16194150 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1132 @@ -39575,6 +43535,7 @@ - gene_reaction_rule: YAL022C - annotation: !!omap - pmid: 10827170 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1133 @@ -39587,6 +43548,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YER056C or YER060W or YER060W-A or YGL186C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1134 @@ -39600,6 +43563,8 @@ - upper_bound: 1000 - gene_reaction_rule: YDL245C or YDR342C or YDR343C or YDR345C or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YMR011W or YNR072W or YOL156W - subsystem: sce04113 Meiosis - yeast + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1135 @@ -39613,6 +43578,8 @@ - upper_bound: 1000 - gene_reaction_rule: YDR536W or YFL011W or YJL219W or YLR081W or YNL318C or YOL156W - subsystem: sce04113 Meiosis - yeast + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1136 @@ -39625,6 +43592,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YKL217W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1137 @@ -39638,6 +43607,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 14871487 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1138 @@ -39651,6 +43621,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 14871487 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1139 @@ -39664,6 +43635,8 @@ - upper_bound: 1000 - gene_reaction_rule: YDL245C or YDR342C or YDR343C or YDR345C or YEL069C or YFL011W or YHR092C or YHR094C or YHR096C or YJL214W or YJL219W or YJR158W or YMR011W or YNR072W or YOL156W - subsystem: sce04113 Meiosis - yeast + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1146 @@ -39676,6 +43649,7 @@ - gene_reaction_rule: YIL013C or YOR011W - annotation: !!omap - pmid: 12077145 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1147 @@ -39688,6 +43662,7 @@ - gene_reaction_rule: YIL013C or YOR011W - annotation: !!omap - pmid: 12077145 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1148 @@ -39700,6 +43675,7 @@ - gene_reaction_rule: YIL013C or YOR011W - annotation: !!omap - pmid: 17434796 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1149 @@ -39711,6 +43687,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 15201274 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1151 @@ -39723,6 +43700,7 @@ - gene_reaction_rule: YIL134W - annotation: !!omap - pmid: 8631763 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1161 @@ -39735,6 +43713,7 @@ - gene_reaction_rule: YIL013C or YOR011W - annotation: !!omap - pmid: 12077145 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1162 @@ -39747,6 +43726,7 @@ - gene_reaction_rule: YIL013C or YOR011W - annotation: !!omap - pmid: 17434796 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1164 @@ -39758,6 +43738,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 15215118 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1165 @@ -39772,6 +43753,7 @@ - gene_reaction_rule: YGL225W - annotation: !!omap - pmid: 9395539 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1166 @@ -39785,6 +43767,7 @@ - subsystem: sce04113 Meiosis - yeast - annotation: !!omap - pmid: 10618490 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1167 @@ -39797,6 +43780,7 @@ - gene_reaction_rule: YJL212C - annotation: !!omap - pmid: 10788431 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1168 @@ -39809,6 +43793,7 @@ - gene_reaction_rule: YDR135C or YLL015W - annotation: !!omap - pmid: 10790694 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1169 @@ -39821,6 +43806,7 @@ - gene_reaction_rule: YCR098C - annotation: !!omap - pmid: 15145930 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1170 @@ -39833,6 +43819,7 @@ - gene_reaction_rule: YCR098C - annotation: !!omap - pmid: 15145930 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1171 @@ -39849,6 +43836,7 @@ - pmid: - 15703210 - 21623372 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1172 @@ -39859,6 +43847,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YFL054C or YLL043W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1173 @@ -39873,6 +43863,7 @@ - gene_reaction_rule: YCL025C or YKR039W or YOL020W or YOR348C or YPL265W - annotation: !!omap - pmid: 9573211 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1174 @@ -39884,6 +43875,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 11486014 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1175 @@ -39900,6 +43892,7 @@ - gene_reaction_rule: YDL198C - annotation: !!omap - pmid: 14998997 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1176 @@ -39912,6 +43905,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YER056C or YER060W or YER060W-A or YGL186C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1177 @@ -39924,6 +43919,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YDR497C or YOL103W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1178 @@ -39936,6 +43933,7 @@ - gene_reaction_rule: YMR319C or YMR058W - annotation: !!omap - pmid: 9115232 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1179 @@ -39947,6 +43945,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 9660806 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1180 @@ -39958,6 +43957,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 10653746 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1181 @@ -39969,6 +43969,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 10653746 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1182 @@ -39980,6 +43981,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 11583838 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1183 @@ -39996,6 +43998,7 @@ - pmid: - 7495881 - 9489675 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1184 @@ -40008,6 +44011,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YEL063C or YKR039W or YNL270C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1185 @@ -40022,6 +44027,7 @@ - gene_reaction_rule: YOL092W or YBR293W - annotation: !!omap - pmid: 15572352 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1186 @@ -40036,6 +44042,7 @@ - gene_reaction_rule: YCL025C or YDR508C or YKR039W or YPL265W - annotation: !!omap - pmid: 8660458 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1187 @@ -40050,6 +44057,7 @@ - gene_reaction_rule: YJR001W - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1188 @@ -40065,6 +44073,7 @@ - subsystem: sce04138 Autophagy - yeast - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1189 @@ -40079,6 +44088,7 @@ - gene_reaction_rule: YER119C - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1190 @@ -40091,6 +44101,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YFL055W or YKR039W or YPL265W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1191 @@ -40101,6 +44113,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR132C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1192 @@ -40115,6 +44129,7 @@ - gene_reaction_rule: YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W or YOL020W - annotation: !!omap - pmid: 9573211 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1193 @@ -40129,6 +44144,7 @@ - gene_reaction_rule: YCR075C - annotation: !!omap - pmid: 11689434 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1194 @@ -40141,6 +44157,7 @@ - gene_reaction_rule: YPR021C - annotation: !!omap - pmid: 14622413 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1195 @@ -40155,6 +44172,7 @@ - gene_reaction_rule: YER119C - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1196 @@ -40167,6 +44185,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YCL025C or YFL055W or YKR039W or YPL265W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1197 @@ -40181,6 +44201,7 @@ - gene_reaction_rule: YJR001W - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1198 @@ -40196,6 +44217,7 @@ - subsystem: sce04138 Autophagy - yeast - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1199 @@ -40208,6 +44230,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YCL025C or YDR508C or YKR039W or YPL265W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1200 @@ -40222,6 +44246,7 @@ - gene_reaction_rule: YOL092W or YBR293W or YCL069W or YMR088C - annotation: !!omap - pmid: 15572352 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1201 @@ -40234,6 +44259,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR069C or YGR191W or YKR039W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1202 @@ -40247,6 +44274,7 @@ - subsystem: sce04138 Autophagy - yeast - annotation: !!omap - pmid: 17021250 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1203 @@ -40261,6 +44289,7 @@ - gene_reaction_rule: YJR001W - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1204 @@ -40276,6 +44305,7 @@ - subsystem: sce04138 Autophagy - yeast - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1205 @@ -40288,6 +44318,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR068C or YBR069C or YCL025C or YDR046C or YKR039W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1206 @@ -40300,6 +44332,7 @@ - gene_reaction_rule: YKL217W - annotation: !!omap - pmid: 17761666 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1207 @@ -40314,6 +44347,7 @@ - gene_reaction_rule: YKL217W - annotation: !!omap - pmid: 10198029 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1208 @@ -40327,6 +44361,7 @@ - subsystem: sce04138 Autophagy - yeast - annotation: !!omap - pmid: 17021250 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1209 @@ -40341,6 +44376,7 @@ - gene_reaction_rule: YJR001W - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1210 @@ -40356,6 +44392,7 @@ - subsystem: sce04138 Autophagy - yeast - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1211 @@ -40368,6 +44405,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR068C or YBR069C or YCL025C or YDR046C or YDR508C or YKR039W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1212 @@ -40382,6 +44421,7 @@ - gene_reaction_rule: YOL092W or YBR293W or YCL069W or YMR088C - annotation: !!omap - pmid: 15572352 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1213 @@ -40394,6 +44434,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YKR039W or YNL268W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1214 @@ -40406,6 +44448,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR068C or YCL025C or YDR046C or YDR508C or YGR055W or YHL036W or YKR039W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1215 @@ -40418,6 +44462,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR068C or YCL025C or YDR046C or YKR039W or YOL020W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1216 @@ -40430,6 +44476,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YKR039W or YOR348C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1217 @@ -40442,6 +44490,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YCL025C or YDR508C or YFL055W or YKR039W or YPL265W or YDR105C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1218 @@ -40456,6 +44506,7 @@ - gene_reaction_rule: YBR069C or YCL025C or YDR046C or YDR508C or YKR039W - annotation: !!omap - pmid: 9489675 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1219 @@ -40470,6 +44521,7 @@ - gene_reaction_rule: YBR068C or YBR069C or YDR046C or YKR039W or YOL020W - annotation: !!omap - pmid: 9573211 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1220 @@ -40483,6 +44535,7 @@ - subsystem: sce04138 Autophagy - yeast - annotation: !!omap - pmid: 17021250 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1221 @@ -40497,6 +44550,7 @@ - gene_reaction_rule: YBR293W or YJR001W - annotation: !!omap - pmid: 15572352 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1222 @@ -40512,6 +44566,7 @@ - subsystem: sce04138 Autophagy - yeast - annotation: !!omap - pmid: 11274162 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1223 @@ -40524,6 +44579,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR068C or YBR069C or YCL025C or YDR046C or YKR039W or YOL020W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1224 @@ -40536,6 +44593,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR068C or YBR069C or YCL025C or YDR046C or YKR039W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1225 @@ -40548,6 +44607,7 @@ - gene_reaction_rule: YIL013C or YOR011W - annotation: !!omap - pmid: 12077145 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1226 @@ -40560,6 +44620,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YLR348C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1227 @@ -40574,6 +44636,7 @@ - gene_reaction_rule: YBR298C or YDL247W or YGR289C or YJR160C - annotation: !!omap - pmid: 7483839 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1228 @@ -40586,6 +44649,7 @@ - gene_reaction_rule: YBR180W - annotation: !!omap - pmid: 12455697 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1229 @@ -40600,6 +44664,7 @@ - pmid: - 16291748 - 9169870 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1230 @@ -40614,6 +44679,7 @@ - gene_reaction_rule: YIL006W - annotation: !!omap - pmid: 16291748 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1231 @@ -40628,6 +44694,7 @@ - gene_reaction_rule: YIL006W - annotation: !!omap - pmid: 16291748 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1232 @@ -40642,6 +44709,7 @@ - gene_reaction_rule: YIL006W - annotation: !!omap - pmid: 16291748 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1235 @@ -40654,6 +44722,7 @@ - gene_reaction_rule: YGR260W - annotation: !!omap - pmid: 10869563 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1236 @@ -40665,6 +44734,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 8993619 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1237 @@ -40679,6 +44749,7 @@ - gene_reaction_rule: YOR130C - annotation: !!omap - pmid: 10428783 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1238 @@ -40691,6 +44762,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YEL063C or YKR039W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1239 @@ -40703,6 +44776,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YKL120W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1241 @@ -40715,6 +44790,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YCR028C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1242 @@ -40726,6 +44803,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 11583838 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1243 @@ -40737,6 +44815,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 10653746 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1244 @@ -40749,6 +44828,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR296C or YCR037C or YJL198W or YML123C or YNR013C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1245 @@ -40761,6 +44842,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YER053C or YJR077C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1249 @@ -40775,6 +44858,7 @@ - gene_reaction_rule: YDR456W or YJL129C - annotation: !!omap - pmid: 3043197 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1250 @@ -40787,6 +44871,7 @@ - gene_reaction_rule: YKL174C - annotation: !!omap - pmid: 15668236 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1251 @@ -40801,6 +44886,7 @@ - gene_reaction_rule: YLL028W or YOR273C - annotation: !!omap - pmid: 9920864 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1252 @@ -40815,6 +44901,7 @@ - gene_reaction_rule: YLL028W or YOR273C - annotation: !!omap - pmid: 11171066 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1253 @@ -40829,6 +44916,7 @@ - gene_reaction_rule: YGL186C - annotation: !!omap - pmid: 12649274 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1254 @@ -40841,6 +44929,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YKL217W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1255 @@ -40853,6 +44943,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YPL274W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1256 @@ -40865,6 +44957,7 @@ - gene_reaction_rule: YNL003C - annotation: !!omap - pmid: 14609944 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1257 @@ -40877,6 +44970,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YLL061W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1258 @@ -40889,6 +44984,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YDR456W or YLR138W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1259 @@ -40901,6 +44998,7 @@ - gene_reaction_rule: YKL174C - annotation: !!omap - pmid: 15668236 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1260 @@ -40917,6 +45015,7 @@ - pmid: - 17218313 - 9920864 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1261 @@ -40931,6 +45030,7 @@ - gene_reaction_rule: YLL028W or YOR273C - annotation: !!omap - pmid: 11171066 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1262 @@ -40945,6 +45045,7 @@ - gene_reaction_rule: YGR138C or YLL028W or YOR273C or YPR156C - annotation: !!omap - pmid: 9920864 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1263 @@ -40959,6 +45060,7 @@ - gene_reaction_rule: YGR138C or YLL028W or YOR273C or YPR156C - annotation: !!omap - pmid: 11171066 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1264 @@ -40971,6 +45073,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YLR348C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1265 @@ -40985,6 +45089,7 @@ - gene_reaction_rule: YJR095W - annotation: !!omap - pmid: 9395087 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1266 @@ -40995,6 +45100,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YBR294W or YLR092W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1267 @@ -41007,6 +45114,7 @@ - gene_reaction_rule: YPL092W - annotation: !!omap - pmid: 10870099 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1268 @@ -41018,6 +45126,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 8293962 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1269 @@ -41030,6 +45139,7 @@ - gene_reaction_rule: YGR096W - annotation: !!omap - pmid: 12411483 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1270 @@ -41042,6 +45152,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YLR237W or YOR071C or YOR192C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1271 @@ -41054,6 +45166,7 @@ - gene_reaction_rule: YPL244C - annotation: !!omap - pmid: 11284009 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1272 @@ -41066,6 +45179,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YBR021W + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1273 @@ -41078,6 +45193,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YHL016C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 2 - !!omap - id: r_1274 @@ -41092,6 +45209,7 @@ - gene_reaction_rule: YBL042C - annotation: !!omap - pmid: 10827169 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1275 @@ -41110,6 +45228,7 @@ - gene_reaction_rule: YBR192W - annotation: !!omap - pmid: 16844075 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1276 @@ -41126,6 +45245,7 @@ - gene_reaction_rule: YBR192W - annotation: !!omap - pmid: 16194150 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1277 @@ -41138,6 +45258,7 @@ - gene_reaction_rule: YLL052C or YPR192W - annotation: !!omap - pmid: 9765289 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1278 @@ -41150,6 +45271,7 @@ - gene_reaction_rule: YIL013C or YOR011W - annotation: !!omap - pmid: 12077145 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_1449 @@ -41161,6 +45283,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1450 @@ -41172,6 +45296,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1451 @@ -41183,6 +45309,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1452 @@ -41194,6 +45322,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1453 @@ -41205,6 +45335,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1454 @@ -41216,6 +45348,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1455 @@ -41227,6 +45361,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1456 @@ -41238,6 +45374,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1457 @@ -41249,6 +45387,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1458 @@ -41260,6 +45400,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1479 @@ -41271,6 +45413,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1480 @@ -41282,6 +45426,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1481 @@ -41293,6 +45439,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1482 @@ -41304,6 +45452,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1483 @@ -41315,6 +45465,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1484 @@ -41326,6 +45478,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1485 @@ -41337,6 +45491,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1486 @@ -41348,6 +45504,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1487 @@ -41359,6 +45517,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1488 @@ -41370,6 +45530,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1509 @@ -41381,6 +45543,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1510 @@ -41392,6 +45556,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1511 @@ -41403,6 +45569,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1512 @@ -41414,6 +45582,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1513 @@ -41425,6 +45595,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1514 @@ -41436,6 +45608,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1515 @@ -41447,6 +45621,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1516 @@ -41458,6 +45634,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1517 @@ -41469,6 +45647,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1518 @@ -41480,6 +45660,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_1542 @@ -41488,6 +45670,8 @@ - s_0003: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1543 - name: (1->3)-beta-D-glucan transport @@ -41496,6 +45680,8 @@ - s_0002: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1545 @@ -41504,6 +45690,8 @@ - s_0022: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1546 - name: (R)-lactate exchange @@ -41511,6 +45699,8 @@ - s_0026: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1547 - name: (R)-mevalonate exchange @@ -41518,6 +45708,8 @@ - s_0029: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1548 - name: (R)-pantothenate exchange @@ -41525,6 +45717,8 @@ - s_0032: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1549 - name: (R,R)-2,3-butanediol exchange @@ -41532,6 +45726,8 @@ - s_0036: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1550 - name: (S)-3-methyl-2-oxopentanoate exchange @@ -41539,6 +45735,8 @@ - s_0058: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1551 - name: (S)-lactate exchange @@ -41546,6 +45744,8 @@ - s_0064: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1552 - name: (S)-malate exchange @@ -41553,6 +45753,8 @@ - s_0067: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1553 - name: 1-(sn-glycero-3-phospho)-1D-myo-inositol exchange @@ -41560,6 +45762,8 @@ - s_0080: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1554 - name: 1-acylglycerophosphocholine exchange @@ -41567,6 +45771,8 @@ - s_0084: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1560 - name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate diffusion @@ -41575,6 +45781,8 @@ - s_1157: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1562 @@ -41584,6 +45792,8 @@ - s_0127: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1563 @@ -41592,6 +45802,8 @@ - s_0133: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1564 - name: 2'-deoxyguanosine exchange @@ -41599,6 +45811,8 @@ - s_0135: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1565 - name: 2'-deoxyinosine exchange @@ -41606,6 +45820,8 @@ - s_0137: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1566 - name: 2'-deoxyuridine exchange @@ -41613,6 +45829,8 @@ - s_0139: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1567 - name: 2-dehydro-3-deoxy-D-arabino-heptonate7-phohsphate transport @@ -41621,6 +45839,8 @@ - s_0350: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1568 @@ -41630,6 +45850,8 @@ - s_0150: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1572 @@ -41638,6 +45860,8 @@ - s_0163: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1573 - name: 2-isopropylmalate transport @@ -41646,6 +45870,8 @@ - s_0163: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1574 @@ -41655,6 +45881,8 @@ - s_0164: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1575 @@ -41664,6 +45892,8 @@ - s_0170: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1576 @@ -41673,6 +45903,8 @@ - s_0171: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1577 @@ -41681,6 +45913,8 @@ - s_0167: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1578 - name: 2-methylbutanal transport @@ -41689,6 +45923,8 @@ - s_0167: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1579 @@ -41698,6 +45934,8 @@ - s_0168: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1580 @@ -41706,6 +45944,8 @@ - s_0170: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1581 - name: 2-methylbutyl acetate exchange @@ -41713,6 +45953,8 @@ - s_0173: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1582 - name: 2-methylpropanal transport @@ -41721,6 +45963,8 @@ - s_0938: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1583 @@ -41730,6 +45974,8 @@ - s_0939: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1585 @@ -41739,6 +45985,8 @@ - s_0179: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1586 @@ -41747,6 +45995,8 @@ - s_0181: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1587 - name: 2-oxoglutarate transport @@ -41755,6 +46005,8 @@ - s_0183: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1588 @@ -41764,6 +46016,8 @@ - s_0181: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1589 @@ -41772,6 +46026,8 @@ - s_0186: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1590 - name: 2-phenylethanol transport @@ -41780,6 +46036,8 @@ - s_0186: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1591 @@ -41789,6 +46047,8 @@ - s_0187: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1595 @@ -41798,6 +46058,8 @@ - s_0011: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1596 @@ -41807,6 +46069,8 @@ - s_0060: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1597 @@ -41816,6 +46080,8 @@ - s_0058: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1598 @@ -41824,6 +46090,8 @@ - s_0235: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1599 - name: 3-methylbutanal transport @@ -41832,6 +46100,8 @@ - s_0235: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1600 @@ -41841,6 +46111,8 @@ - s_0236: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1601 @@ -41850,6 +46122,8 @@ - s_0216: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1603 @@ -41863,6 +46137,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YFL058W + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1604 @@ -41871,6 +46147,8 @@ - s_0272: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1605 - name: 4-aminobenzoate transport @@ -41879,6 +46157,8 @@ - s_0272: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1606 @@ -41888,6 +46168,8 @@ - s_0273: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1607 @@ -41897,6 +46179,8 @@ - s_0275: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1608 @@ -41906,6 +46190,8 @@ - s_0738: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1609 @@ -41915,6 +46201,8 @@ - s_0283: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1610 @@ -41924,6 +46212,8 @@ - s_0284: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1611 @@ -41933,6 +46223,8 @@ - s_0287: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1613 @@ -41944,6 +46236,8 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1614 @@ -41955,6 +46249,8 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1615 @@ -41966,6 +46262,8 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1616 @@ -41977,6 +46275,8 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1617 @@ -41988,6 +46288,8 @@ - s_1493: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1618 @@ -41999,6 +46301,8 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1619 @@ -42013,6 +46317,7 @@ - gene_reaction_rule: YER037W - annotation: !!omap - pmid: 23670538 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_1620 @@ -42024,6 +46329,8 @@ - s_1565: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1621 @@ -42032,6 +46339,8 @@ - s_0316: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1622 - name: 5-aminolevulinate transport @@ -42040,6 +46349,8 @@ - s_0317: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1623 @@ -42053,6 +46364,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YER183C + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1624 @@ -42068,6 +46381,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YER183C + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1625 @@ -42076,6 +46391,8 @@ - s_0320: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1627 - name: 7,8-diaminononanoate exchange @@ -42083,6 +46400,8 @@ - s_0342: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1628 - name: 7,8-diaminononanoate transport @@ -42091,6 +46410,8 @@ - s_0342: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1629 @@ -42099,6 +46420,8 @@ - s_0354: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1630 - name: 9H-xanthine exchange @@ -42106,6 +46429,8 @@ - s_0358: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1631 - name: acetaldehyde exchange @@ -42113,6 +46438,8 @@ - s_0360: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1632 - name: acetaldehyde transport @@ -42121,6 +46448,8 @@ - s_0361: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1633 @@ -42130,6 +46459,8 @@ - s_0360: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1634 @@ -42138,6 +46469,8 @@ - s_0364: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1635 - name: acetate transport @@ -42146,6 +46479,8 @@ - s_0366: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1637 @@ -42155,6 +46490,8 @@ - s_0377: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1638 @@ -42164,6 +46501,8 @@ - s_1237: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1639 @@ -42172,6 +46511,8 @@ - s_0384: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1640 - name: adenine transport @@ -42180,6 +46521,8 @@ - s_0385: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1641 @@ -42188,6 +46531,8 @@ - s_0391: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1642 - name: adenosine 3',5'-bisphosphate transport @@ -42196,6 +46541,8 @@ - s_0392: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1643 @@ -42204,6 +46551,8 @@ - s_0387: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1644 - name: ADP transport @@ -42212,6 +46561,8 @@ - s_0398: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1645 @@ -42221,6 +46572,8 @@ - s_0395: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1647 @@ -42230,6 +46583,8 @@ - s_0184: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1648 @@ -42238,6 +46593,8 @@ - s_0406: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1649 - name: allantoin exchange @@ -42245,6 +46602,8 @@ - s_0408: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1650 - name: trehalose exchange @@ -42252,6 +46611,8 @@ - s_1521: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1651 - name: alpha-D-glucosamine 6-phosphate exchange @@ -42259,6 +46620,8 @@ - s_0413: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1652 - name: alpha-ketoglutarate/malate transporter @@ -42269,6 +46632,8 @@ - s_0181: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1654 @@ -42277,6 +46642,8 @@ - s_0420: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1656 - name: AMP transport @@ -42285,6 +46652,8 @@ - s_0425: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1657 @@ -42298,6 +46667,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 9874237 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1658 @@ -42307,6 +46677,8 @@ - s_0971: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1659 @@ -42318,6 +46690,8 @@ - s_0995: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1660 @@ -42327,6 +46701,8 @@ - s_0438: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1661 @@ -42336,6 +46712,8 @@ - s_0435: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1663 @@ -42344,6 +46722,8 @@ - s_0446: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1664 - name: bicarbonate formation @@ -42354,6 +46734,8 @@ - s_0807: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1665 @@ -42365,6 +46747,8 @@ - s_0808: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1667 @@ -42377,6 +46761,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YNL036W + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1668 @@ -42388,6 +46774,8 @@ - s_0805: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1669 @@ -42397,6 +46785,8 @@ - s_0448: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1671 @@ -42405,6 +46795,8 @@ - s_0452: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1672 - name: carbon dioxide exchange @@ -42412,6 +46804,8 @@ - s_0458: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1673 - name: carnitine transport @@ -42420,6 +46814,8 @@ - s_0024: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1674 @@ -42431,6 +46827,8 @@ - s_1237: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1675 @@ -42440,6 +46838,8 @@ - s_0468: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1676 @@ -42449,6 +46849,8 @@ - s_0476: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1677 @@ -42458,6 +46860,8 @@ - s_0482: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1678 @@ -42467,6 +46871,8 @@ - s_0500: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1679 @@ -42476,6 +46882,8 @@ - s_0479: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1680 @@ -42485,6 +46893,8 @@ - s_0485: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1681 @@ -42494,6 +46904,8 @@ - s_0503: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1682 @@ -42508,6 +46920,8 @@ - s_1569: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1683 @@ -42516,6 +46930,8 @@ - s_0513: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1684 - name: choline transport @@ -42524,6 +46940,8 @@ - s_0512: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1685 @@ -42534,6 +46952,8 @@ - s_1399: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1686 @@ -42543,6 +46963,8 @@ - s_0523: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1687 @@ -42551,6 +46973,8 @@ - s_0523: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1688 - name: citrate/isocitrate antiport @@ -42561,6 +46985,8 @@ - s_0942: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1689 @@ -42572,6 +46998,8 @@ - s_0525: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1690 @@ -42583,6 +47011,8 @@ - s_1408: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1691 @@ -42592,6 +47022,8 @@ - s_0457: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1694 @@ -42601,6 +47033,8 @@ - s_0461: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1695 @@ -42610,6 +47044,8 @@ - s_0462: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1696 @@ -42619,6 +47055,8 @@ - s_0460: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1697 @@ -42628,6 +47066,8 @@ - s_0458: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1698 @@ -42637,6 +47077,8 @@ - s_0530: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1699 @@ -42646,6 +47088,8 @@ - s_0533: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1700 @@ -42655,6 +47099,8 @@ - s_0534: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1702 @@ -42663,6 +47109,8 @@ - s_0544: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1703 - name: cytidylate kinase (CMP) @@ -42673,6 +47121,8 @@ - s_0526: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1704 @@ -42684,6 +47134,8 @@ - s_0589: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1705 @@ -42692,6 +47144,8 @@ - s_0546: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1706 - name: D-arabinose exchange @@ -42699,6 +47153,8 @@ - s_0549: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1707 - name: D-arabinose transport @@ -42707,6 +47163,8 @@ - s_0549: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1708 @@ -42716,6 +47174,8 @@ - s_0552: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1709 @@ -42724,6 +47184,8 @@ - s_0554: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1710 - name: D-galactose exchange @@ -42731,6 +47193,8 @@ - s_0559: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1711 - name: D-galacturonate exchange @@ -42738,6 +47202,8 @@ - s_0560: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1712 - name: D-glucitol exchange @@ -42745,6 +47211,8 @@ - s_0562: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1713 - name: D-glucosamine 6-phosphate uniport @@ -42753,6 +47221,8 @@ - s_0413: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1714 @@ -42761,6 +47231,8 @@ - s_0565: -1 - lower_bound: -1 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1715 - name: D-mannose exchange @@ -42768,6 +47240,8 @@ - s_0572: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1716 - name: D-ribose exchange @@ -42775,6 +47249,8 @@ - s_0576: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1717 - name: D-sorbitol transport @@ -42783,6 +47259,8 @@ - s_0562: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1718 @@ -42791,6 +47269,8 @@ - s_0579: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1719 - name: D-xylose transport @@ -42799,6 +47279,8 @@ - s_0579: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1720 @@ -42808,6 +47290,8 @@ - s_0583: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1721 @@ -42817,6 +47301,8 @@ - s_0588: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1722 @@ -42829,6 +47315,8 @@ - s_0950: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1723 @@ -42841,6 +47329,8 @@ - s_0803: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1724 @@ -42853,6 +47343,8 @@ - s_0846: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1725 @@ -42865,6 +47357,8 @@ - s_0803: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1726 @@ -42874,6 +47368,8 @@ - s_0593: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1727 @@ -42882,6 +47378,8 @@ - s_0597: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1728 - name: deoxyadenosine transport @@ -42890,6 +47388,8 @@ - s_0133: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1729 @@ -42902,6 +47402,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YDL166C + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1730 @@ -42910,6 +47412,8 @@ - s_0611: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1731 - name: deoxycytidine transport @@ -42918,6 +47422,8 @@ - s_0611: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1732 @@ -42927,6 +47433,8 @@ - s_0135: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1733 @@ -42936,6 +47444,8 @@ - s_0137: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1734 @@ -42948,6 +47458,8 @@ - s_0794: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1735 @@ -42957,6 +47469,8 @@ - s_0139: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1736 @@ -42969,6 +47483,8 @@ - s_0794: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1737 @@ -42978,6 +47494,8 @@ - s_0614: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1738 @@ -42987,6 +47505,8 @@ - s_0344: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1739 @@ -43000,6 +47520,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YDR071C + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1743 @@ -43009,6 +47531,8 @@ - s_0626: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1744 @@ -43021,6 +47545,8 @@ - s_0803: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1745 @@ -43030,6 +47556,8 @@ - s_0348: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1746 @@ -43041,6 +47569,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 22672422 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1747 @@ -43050,6 +47579,8 @@ - s_0638: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1748 @@ -43059,6 +47590,8 @@ - s_0646: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1749 @@ -43067,6 +47600,8 @@ - s_0651: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1750 - name: dTTP uniport @@ -43075,6 +47610,8 @@ - s_0651: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1751 @@ -43084,6 +47621,8 @@ - s_0653: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1752 @@ -43093,6 +47632,8 @@ - s_0655: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1753 @@ -43101,6 +47642,8 @@ - s_0659: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1754 - name: ergosta-5,6,22,24,(28)-tetraen-3beta-ol transport @@ -43109,6 +47652,8 @@ - s_0663: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1757 @@ -43117,6 +47662,8 @@ - s_0668: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1758 - name: ergosterol transport @@ -43125,6 +47672,8 @@ - s_0667: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1759 @@ -43134,6 +47683,8 @@ - s_0669: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1760 @@ -43143,6 +47694,8 @@ - s_0666: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1761 @@ -43151,6 +47704,8 @@ - s_0681: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1762 - name: ethanol transport @@ -43159,6 +47714,8 @@ - s_0681: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1763 @@ -43168,6 +47725,8 @@ - s_0682: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1764 @@ -43176,6 +47735,8 @@ - s_0684: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1765 - name: ethyl acetate exchange @@ -43183,6 +47744,8 @@ - s_0686: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1766 - name: farnesyl diphosphate transport @@ -43191,6 +47754,8 @@ - s_0191: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1770 @@ -43200,6 +47765,8 @@ - s_0600: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1771 @@ -43209,6 +47776,8 @@ - s_1070: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1772 @@ -43218,6 +47787,8 @@ - s_1166: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1774 @@ -43227,6 +47798,8 @@ - s_1291: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1775 @@ -43236,6 +47809,8 @@ - s_1298: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1776 @@ -43245,6 +47820,8 @@ - s_1253: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1777 @@ -43254,6 +47831,8 @@ - s_1163: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1788 @@ -43262,6 +47841,8 @@ - s_0702: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1790 - name: FMN adenylyltransferase @@ -43274,6 +47855,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YDL045C + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1791 @@ -43282,6 +47865,8 @@ - s_0715: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1792 - name: folic acid exchange @@ -43289,6 +47874,8 @@ - s_0720: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1793 - name: formate exchange @@ -43296,6 +47883,8 @@ - s_0723: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1794 - name: formate transport @@ -43304,6 +47893,8 @@ - s_0724: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1795 @@ -43313,6 +47904,8 @@ - s_0723: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1796 @@ -43322,6 +47915,8 @@ - s_0726: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1797 @@ -43334,6 +47929,8 @@ - s_0794: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1798 @@ -43342,6 +47939,8 @@ - s_0726: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1800 - name: gamma-aminobutyrate exchange @@ -43349,6 +47948,8 @@ - s_0736: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1801 - name: GDP transport @@ -43357,6 +47958,8 @@ - s_0740: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1802 @@ -43366,6 +47969,8 @@ - s_0742: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1803 @@ -43375,6 +47980,8 @@ - s_0744: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1805 @@ -43385,6 +47992,8 @@ - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: YBR241C or YGL104C + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1806 @@ -43393,6 +48002,8 @@ - s_0755: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1807 - name: glutathione exchange @@ -43400,6 +48011,8 @@ - s_0751: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1808 - name: glycerol exchange @@ -43407,6 +48020,8 @@ - s_0766: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1809 - name: glycerol-3-phosphate shuttle @@ -43417,6 +48032,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 22672422 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1810 @@ -43425,6 +48041,8 @@ - s_1004: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1811 - name: glycine transport @@ -43433,6 +48051,8 @@ - s_1005: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1812 @@ -43442,6 +48062,8 @@ - s_0777: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1813 @@ -43451,6 +48073,8 @@ - s_0776: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1814 @@ -43459,6 +48083,8 @@ - s_0776: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1815 - name: glyoxylate exchange @@ -43466,6 +48092,8 @@ - s_0780: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1816 - name: glyoxylate transport @@ -43474,6 +48102,8 @@ - s_0780: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1817 @@ -43483,6 +48113,8 @@ - s_0781: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1818 @@ -43491,6 +48123,8 @@ - s_0788: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1819 - name: guanine transport @@ -43499,6 +48133,8 @@ - s_0789: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1820 @@ -43507,6 +48143,8 @@ - s_0791: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1821 - name: guanosine kinase @@ -43518,6 +48156,8 @@ - s_0794: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1822 @@ -43527,6 +48167,8 @@ - s_0792: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1823 @@ -43536,6 +48178,8 @@ - s_0791: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1824 @@ -43545,6 +48189,8 @@ - s_0796: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1825 @@ -43554,6 +48200,8 @@ - s_0795: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1826 @@ -43563,6 +48211,8 @@ - s_0797: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1827 @@ -43572,6 +48222,8 @@ - s_0798: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1829 @@ -43581,6 +48233,8 @@ - s_0800: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1830 @@ -43590,6 +48244,8 @@ - s_0801: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1831 @@ -43599,6 +48255,8 @@ - s_0802: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1832 @@ -43607,6 +48265,8 @@ - s_0796: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1833 - name: hexacosanoyl-CoA transport @@ -43615,6 +48275,8 @@ - s_0817: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1834 @@ -43623,6 +48285,8 @@ - s_0826: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1835 - name: hexadecanoate (n-C16:0) transport @@ -43631,6 +48295,8 @@ - s_1288: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1836 @@ -43640,6 +48306,8 @@ - s_1295: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1837 @@ -43649,6 +48317,8 @@ - s_1008: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1838 @@ -43671,6 +48341,7 @@ - sce01230 Biosynthesis of amino acids - annotation: !!omap - ec-code: 2.3.3.14 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_1839 @@ -43680,6 +48351,8 @@ - s_0839: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1840 @@ -43689,6 +48362,8 @@ - s_0221: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1841 @@ -43697,6 +48372,8 @@ - s_0844: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1842 - name: hypoxanthine transport @@ -43705,6 +48382,8 @@ - s_0844: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1843 @@ -43713,6 +48392,8 @@ - s_0851: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1844 - name: indole-3-acetaldehyde transport @@ -43721,6 +48402,8 @@ - s_0852: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1845 @@ -43730,6 +48413,8 @@ - s_0851: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1846 @@ -43739,6 +48424,8 @@ - s_0854: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1847 @@ -43747,6 +48434,8 @@ - s_0857: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1848 - name: inosine transport @@ -43755,6 +48444,8 @@ - s_0857: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1849 @@ -43764,6 +48455,8 @@ - s_1159: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1850 @@ -43776,6 +48469,8 @@ - s_0856: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1851 @@ -43785,6 +48480,8 @@ - s_0895: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1852 @@ -43794,6 +48491,8 @@ - s_0901: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1853 @@ -43803,6 +48502,8 @@ - s_0907: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1854 @@ -43812,6 +48513,8 @@ - s_0913: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1855 @@ -43821,6 +48524,8 @@ - s_0919: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1856 @@ -43830,6 +48535,8 @@ - s_0898: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1857 @@ -43839,6 +48546,8 @@ - s_0904: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1858 @@ -43848,6 +48557,8 @@ - s_0910: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1859 @@ -43857,6 +48568,8 @@ - s_0916: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1860 @@ -43866,6 +48579,8 @@ - s_0922: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1861 @@ -43874,6 +48589,8 @@ - s_0925: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1862 - name: isoamyl acetate exchange @@ -43881,6 +48598,8 @@ - s_0928: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1863 - name: isoamyl alcohol transport @@ -43889,6 +48608,8 @@ - s_0930: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1864 @@ -43898,6 +48619,8 @@ - s_0931: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1865 @@ -43906,6 +48629,8 @@ - s_0930: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1866 - name: isobutanol exchange @@ -43913,6 +48638,8 @@ - s_0933: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1867 - name: isobutyl acetate exchange @@ -43920,6 +48647,8 @@ - s_0936: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1868 - name: isobutyl alcohol transport @@ -43928,6 +48657,8 @@ - s_0933: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1869 @@ -43937,6 +48668,8 @@ - s_0934: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1870 @@ -43945,6 +48678,8 @@ - s_0938: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1871 - name: L-1-pyrroline-3-hydroxy-5-carboxylate spontaneous conversion to L-4-hydroxyglutamate semialdehyde @@ -43955,6 +48690,8 @@ - s_0954: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1872 @@ -43966,6 +48703,8 @@ - s_0952: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1873 @@ -43974,6 +48713,8 @@ - s_0956: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1874 - name: L-alanine transport @@ -43982,6 +48723,8 @@ - s_0957: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1875 @@ -43990,6 +48733,8 @@ - s_0962: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1876 - name: L-arabinitol transport @@ -43998,6 +48743,8 @@ - s_0962: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1877 @@ -44007,6 +48754,8 @@ - s_0964: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1878 @@ -44015,6 +48764,8 @@ - s_0964: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1879 - name: L-arginine exchange @@ -44022,6 +48773,8 @@ - s_0966: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1880 - name: L-asparagine exchange @@ -44029,6 +48782,8 @@ - s_0970: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1881 - name: L-aspartate exchange @@ -44036,6 +48791,8 @@ - s_0974: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1882 - name: L-carnitine transport @@ -44044,6 +48801,8 @@ - s_0023: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1883 @@ -44052,6 +48811,8 @@ - s_0982: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1884 - name: L-erythro-4-hydroxyglutamate transport @@ -44060,6 +48821,8 @@ - s_0678: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1885 @@ -44069,6 +48832,8 @@ - s_0679: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1886 @@ -44077,6 +48842,8 @@ - s_0990: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1887 - name: L-glutamate 5-semialdehyde dehydratase @@ -44087,6 +48854,8 @@ - s_0997: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1889 @@ -44095,6 +48864,8 @@ - s_0992: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1890 - name: L-glutamate transport @@ -44103,6 +48874,8 @@ - s_0994: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1891 @@ -44111,6 +48884,8 @@ - s_1000: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1892 - name: L-glutamine transport @@ -44119,6 +48894,8 @@ - s_1001: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1893 @@ -44127,6 +48904,8 @@ - s_1007: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1895 - name: L-homoserine transport @@ -44135,6 +48914,8 @@ - s_1015: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1896 @@ -44143,6 +48924,8 @@ - s_1015: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1897 - name: L-isoleucine exchange @@ -44150,6 +48933,8 @@ - s_1017: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1898 - name: L-isoleucine transport @@ -44158,6 +48943,8 @@ - s_1018: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1899 @@ -44166,6 +48953,8 @@ - s_1022: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1900 - name: L-lysine exchange @@ -44173,6 +48962,8 @@ - s_1026: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1901 - name: L-malate transport @@ -44181,6 +48972,8 @@ - s_0067: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1902 @@ -44189,6 +48982,8 @@ - s_1030: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1903 - name: L-phenylalanine exchange @@ -44196,6 +48991,8 @@ - s_1033: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1904 - name: L-proline exchange @@ -44203,6 +49000,8 @@ - s_1036: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1905 - name: L-proline transport @@ -44211,6 +49010,8 @@ - s_1037: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1906 @@ -44219,6 +49020,8 @@ - s_1041: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1907 - name: L-serine transport @@ -44227,6 +49030,8 @@ - s_1040: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1908 @@ -44236,6 +49041,8 @@ - s_0990: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1909 @@ -44244,6 +49051,8 @@ - s_1044: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1910 - name: L-sorbose transport @@ -44252,6 +49061,8 @@ - s_1044: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1911 @@ -44260,6 +49071,8 @@ - s_1046: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1912 - name: L-tryptophan exchange @@ -44267,6 +49080,8 @@ - s_1049: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1913 - name: L-tyrosine exchange @@ -44274,6 +49089,8 @@ - s_1052: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1914 - name: L-valine exchange @@ -44281,6 +49098,8 @@ - s_1057: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1915 - name: lanosterol exchange @@ -44288,6 +49107,8 @@ - s_1061: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1916 - name: laurate exchange @@ -44295,6 +49116,8 @@ - s_1067: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1919 - name: lysine transport @@ -44303,6 +49126,8 @@ - s_1027: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1920 @@ -44312,6 +49137,8 @@ - s_0862: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1921 @@ -44321,6 +49148,8 @@ - s_0868: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1922 @@ -44330,6 +49159,8 @@ - s_0874: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1923 @@ -44339,6 +49170,8 @@ - s_0880: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1924 @@ -44348,6 +49181,8 @@ - s_0886: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1925 @@ -44357,6 +49192,8 @@ - s_0865: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1926 @@ -44366,6 +49203,8 @@ - s_0871: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1927 @@ -44375,6 +49214,8 @@ - s_0877: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1928 @@ -44384,6 +49225,8 @@ - s_0883: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1929 @@ -44393,6 +49236,8 @@ - s_0889: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1930 @@ -44404,6 +49249,8 @@ - s_1274: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1931 @@ -44412,6 +49259,8 @@ - s_1106: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1932 - name: mannan transport @@ -44420,6 +49269,8 @@ - s_1108: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1935 @@ -44429,6 +49280,8 @@ - s_1031: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1936 @@ -44439,6 +49292,8 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1937 @@ -44448,6 +49303,8 @@ - s_1117: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1938 @@ -44457,6 +49314,8 @@ - s_1123: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1939 @@ -44466,6 +49325,8 @@ - s_1129: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1940 @@ -44475,6 +49336,8 @@ - s_1135: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1941 @@ -44484,6 +49347,8 @@ - s_1141: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1942 @@ -44493,6 +49358,8 @@ - s_1120: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1943 @@ -44502,6 +49369,8 @@ - s_1126: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1944 @@ -44511,6 +49380,8 @@ - s_1132: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1945 @@ -44520,6 +49391,8 @@ - s_1138: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1946 @@ -44529,6 +49402,8 @@ - s_1144: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1947 @@ -44537,6 +49412,8 @@ - s_1154: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1952 - name: N,N'-diformyldityrosine exchange @@ -44544,6 +49421,8 @@ - s_1186: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1963 - name: NADP(+) transport @@ -44552,6 +49431,8 @@ - s_1208: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1964 @@ -44561,6 +49442,8 @@ - s_1213: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1965 @@ -44570,6 +49453,8 @@ - s_0421: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1966 @@ -44579,6 +49464,8 @@ - s_1217: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1967 @@ -44587,6 +49474,8 @@ - s_1220: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1968 - name: NMN exchange @@ -44594,6 +49483,8 @@ - s_1225: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1970 - name: NMN transport @@ -44602,6 +49493,8 @@ - s_1227: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1971 @@ -44611,6 +49504,8 @@ - s_1228: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1972 @@ -44620,6 +49515,8 @@ - s_1225: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1974 @@ -44632,6 +49529,8 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1975 @@ -44644,6 +49543,8 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1976 @@ -44653,6 +49554,8 @@ - s_1236: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1977 @@ -44662,6 +49565,8 @@ - s_1276: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1978 @@ -44671,6 +49576,8 @@ - s_1278: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1979 @@ -44680,6 +49587,8 @@ - s_1277: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1980 @@ -44689,6 +49598,8 @@ - s_1279: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1981 @@ -44698,6 +49609,8 @@ - s_1450: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1984 @@ -44706,6 +49619,8 @@ - s_1250: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1987 - name: ornithine exchange @@ -44713,6 +49628,8 @@ - s_1267: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1988 - name: oxaloacetate transport @@ -44721,6 +49638,8 @@ - s_1272: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1989 @@ -44729,6 +49648,8 @@ - s_1272: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1990 - name: oxidized glutathione uniport @@ -44737,6 +49658,8 @@ - s_0755: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1991 @@ -44746,6 +49669,8 @@ - s_1623: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1992 @@ -44754,6 +49679,8 @@ - s_1277: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1993 - name: palmitate exchange @@ -44761,6 +49688,8 @@ - s_1288: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1994 - name: palmitoleate exchange @@ -44768,6 +49697,8 @@ - s_1295: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_1995 - name: palmitoyl-CoA transport @@ -44776,6 +49707,8 @@ - s_1303: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1996 @@ -44785,6 +49718,8 @@ - s_1308: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1997 @@ -44797,6 +49732,8 @@ - s_1308: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_1998 @@ -44806,6 +49743,8 @@ - s_0391: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_1999 @@ -44814,6 +49753,8 @@ - s_1309: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2000 - name: phenethyl acetate exchange @@ -44821,6 +49762,8 @@ - s_1317: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2001 - name: phenylacetaldehyde exchange @@ -44828,6 +49771,8 @@ - s_1319: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2002 - name: phenylacetaldehyde transport @@ -44836,6 +49781,8 @@ - s_1319: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2003 @@ -44845,6 +49792,8 @@ - s_1320: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2004 @@ -44854,6 +49803,8 @@ - s_1034: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2005 @@ -44862,6 +49813,8 @@ - s_1324: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2008 - name: phosphate transport @@ -44870,6 +49823,8 @@ - s_1329: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2020 @@ -44878,6 +49833,8 @@ - s_1374: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2022 - name: protoporphyrinogen IX transport @@ -44886,6 +49843,8 @@ - s_1385: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2023 @@ -44895,6 +49854,8 @@ - s_1387: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2024 @@ -44903,6 +49864,8 @@ - s_1390: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2025 - name: pyridoxal kinase @@ -44915,6 +49878,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YNR027W + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2026 @@ -44927,6 +49892,8 @@ - s_1395: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2027 @@ -44938,6 +49905,8 @@ - s_1395: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2028 @@ -44946,6 +49915,8 @@ - s_1397: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2029 - name: pyridoxine kinase @@ -44961,6 +49932,7 @@ - subsystem: sce00750 Vitamin B6 metabolism - annotation: !!omap - ec-code: 2.7.1.35 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_2030 @@ -44972,6 +49944,8 @@ - s_1322: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2031 @@ -44983,6 +49957,8 @@ - s_1556: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2032 @@ -44992,6 +49968,8 @@ - s_0636: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2033 @@ -45000,6 +49978,8 @@ - s_1400: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2034 - name: pyruvate transport @@ -45013,6 +49993,7 @@ - gene_reaction_rule: (YGL080W and YGR243W) or (YGL080W and YHR162W) - annotation: !!omap - pmid: 22628558 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2036 @@ -45022,6 +50003,8 @@ - s_1404: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2037 @@ -45031,6 +50014,8 @@ - s_1619: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2038 @@ -45039,6 +50024,8 @@ - s_1406: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2039 - name: riboflavin transport @@ -45047,6 +50034,8 @@ - s_1407: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2040 @@ -45056,6 +50045,8 @@ - s_1406: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2041 @@ -45065,6 +50056,8 @@ - s_0576: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2042 @@ -45074,6 +50067,8 @@ - s_1415: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2043 @@ -45082,6 +50077,8 @@ - s_1418: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2044 - name: S-methyl-L-methionine exchange @@ -45089,6 +50086,8 @@ - s_1425: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2045 - name: serine transport @@ -45097,6 +50096,8 @@ - s_1042: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2046 @@ -45105,6 +50106,8 @@ - s_1435: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2049 - name: sodium exchange @@ -45112,6 +50115,8 @@ - s_1438: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2050 - name: spermidine acetyltransferase @@ -45123,6 +50128,8 @@ - s_1439: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2051 @@ -45131,6 +50138,8 @@ - s_1440: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2052 - name: spermine exchange @@ -45138,6 +50147,8 @@ - s_1443: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2053 - name: squalene transport @@ -45146,6 +50157,8 @@ - s_1448: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2054 @@ -45155,6 +50168,8 @@ - s_0038: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2055 @@ -45163,6 +50178,8 @@ - s_1450: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2056 - name: succinate exchange @@ -45170,6 +50187,8 @@ - s_1459: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2057 - name: succinate transport @@ -45178,6 +50197,8 @@ - s_1459: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2058 @@ -45186,6 +50207,8 @@ - s_1466: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2060 - name: sulphate exchange @@ -45193,6 +50216,8 @@ - s_1468: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2061 - name: sulphite exchange @@ -45200,6 +50225,8 @@ - s_1470: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2062 - name: taurine exchange @@ -45207,6 +50234,8 @@ - s_1472: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2063 - name: tetracosanoyl-CoA transport @@ -45215,6 +50244,8 @@ - s_1480: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2064 @@ -45227,6 +50258,8 @@ - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: YDL024C + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2065 @@ -45239,6 +50272,8 @@ - s_1489: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2066 @@ -45247,6 +50282,8 @@ - s_1476: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2067 - name: thiamine(1+) exchange @@ -45254,6 +50291,8 @@ - s_1490: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2068 - name: thiamine(1+) monophosphate exchange @@ -45261,6 +50300,8 @@ - s_1498: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2069 - name: thiamine-phosphate kinase @@ -45271,6 +50312,8 @@ - s_1497: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2070 @@ -45290,6 +50333,8 @@ - s_1408: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2071 @@ -45309,6 +50354,8 @@ - s_1399: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2072 @@ -45318,6 +50365,8 @@ - s_1047: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2073 @@ -45326,6 +50375,8 @@ - s_1494: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2074 - name: thymidine kinase (ATP:thymidine) @@ -45337,6 +50388,8 @@ - s_1493: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2075 @@ -45346,6 +50399,8 @@ - s_1494: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2079 @@ -45360,6 +50415,7 @@ - gene_reaction_rule: YGR289C - annotation: !!omap - pmid: 10957961 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2080 @@ -45369,6 +50425,8 @@ - s_1522: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2082 @@ -45378,6 +50436,8 @@ - s_1050: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2083 @@ -45386,6 +50446,8 @@ - s_1530: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2084 - name: tryptophol transport @@ -45394,6 +50456,8 @@ - s_1530: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2085 @@ -45403,6 +50467,8 @@ - s_1531: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2086 @@ -45412,6 +50478,8 @@ - s_1053: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2087 @@ -45421,6 +50489,8 @@ - s_1054: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2089 @@ -45430,6 +50500,8 @@ - s_1548: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2090 @@ -45438,6 +50510,8 @@ - s_1551: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2091 - name: urea exchange @@ -45445,6 +50519,8 @@ - s_1553: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2092 - name: uridine exchange @@ -45452,6 +50528,8 @@ - s_1557: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2093 - name: valine transport @@ -45460,6 +50538,8 @@ - s_1058: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2094 @@ -45469,6 +50549,8 @@ - s_0804: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2095 @@ -45478,6 +50560,8 @@ - s_0806: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2096 @@ -45487,6 +50571,8 @@ - s_0807: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2097 @@ -45496,6 +50582,8 @@ - s_0808: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2098 @@ -45505,6 +50593,8 @@ - s_0809: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2099 @@ -45514,6 +50604,8 @@ - s_0810: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2100 @@ -45522,6 +50614,8 @@ - s_0805: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2101 - name: xanthine transport @@ -45530,6 +50624,8 @@ - s_0358: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2102 @@ -45538,6 +50634,8 @@ - s_1564: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2103 - name: xanthosine transport @@ -45546,6 +50644,8 @@ - s_1564: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2104 @@ -45554,6 +50654,8 @@ - s_1567: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2105 - name: xylitol transport @@ -45562,6 +50664,8 @@ - s_1567: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2106 @@ -45570,6 +50674,8 @@ - s_1571: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2107 - name: zymosterol transport @@ -45578,6 +50684,8 @@ - s_1569: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2108 @@ -45590,6 +50698,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 18687109 + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_2111 @@ -45598,6 +50707,8 @@ - s_0450: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000632 - confidence_score: 0 - !!omap - id: r_2112 @@ -45615,6 +50726,7 @@ - ec-code: 2.6.1.7 - kegg.reaction: R01959 - pmid: 18205391 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2113 @@ -45626,6 +50738,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 18205391 + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2114 @@ -45638,6 +50751,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 18205391 + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2115 @@ -45662,6 +50776,7 @@ - ec-code: 1.1.1.1 - kegg.reaction: R00754 - pmid: 12499363 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2116 @@ -45687,6 +50802,7 @@ - annotation: !!omap - ec-code: 1.2.1.3 - kegg.reaction: R00711 + - sbo: SBO:0000176 - confidence_score: 2 - !!omap - id: r_2117 @@ -45713,6 +50829,7 @@ - pmid: - 9491082 - 9491083 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2118 @@ -45739,6 +50856,7 @@ - pmid: - 9491082 - 9491083 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2119 @@ -45765,6 +50883,7 @@ - pmid: - 9491082 - 9491083 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2125 @@ -45777,6 +50896,7 @@ - annotation: !!omap - kegg.reaction: R00197 - pmid: 22672422 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2126 @@ -45802,6 +50922,7 @@ - pmid: - 21663798 - 22672422 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2129 @@ -45813,6 +50934,7 @@ - upper_bound: 1000 - annotation: !!omap - pmid: 22672422 + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2131 @@ -45841,6 +50963,7 @@ - pmid: - 1989987 - 8099357 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2132 @@ -45855,6 +50978,7 @@ - gene_reaction_rule: YOR222W or YPL134C - annotation: !!omap - pmid: 16844075 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2134 @@ -45863,6 +50987,8 @@ - s_2766: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2136 - name: 14-demethyllanosterol transport @@ -45871,6 +50997,8 @@ - s_2766: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2137 @@ -45879,6 +51007,8 @@ - s_2768: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2139 - name: ergosta-5,7,22,24(28)-tetraen-3beta-ol transport @@ -45887,6 +51017,8 @@ - s_2768: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2140 @@ -45910,6 +51042,7 @@ - annotation: !!omap - ec-code: 2.3.1.86 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2141 @@ -45933,6 +51066,7 @@ - annotation: !!omap - ec-code: 2.3.1.86 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2142 @@ -45955,6 +51089,7 @@ - annotation: !!omap - ec-code: 2.3.1.41 - pmid: 8412701 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2143 @@ -45977,6 +51112,7 @@ - annotation: !!omap - ec-code: 2.3.1.41 - pmid: 8412701 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2144 @@ -45999,6 +51135,7 @@ - annotation: !!omap - ec-code: 2.3.1.41 - pmid: 8412701 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2145 @@ -46021,6 +51158,7 @@ - annotation: !!omap - ec-code: 1.1.1.100 - pmid: 9388293 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2146 @@ -46043,6 +51181,7 @@ - annotation: !!omap - ec-code: 1.1.1.100 - pmid: 9388293 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2147 @@ -46065,6 +51204,7 @@ - annotation: !!omap - ec-code: 1.1.1.100 - pmid: 9388293 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2148 @@ -46079,6 +51219,7 @@ - annotation: !!omap - ec-code: 4.2.1.- - pmid: 15387819 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2149 @@ -46093,6 +51234,7 @@ - annotation: !!omap - ec-code: 4.2.1.- - pmid: 15387819 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2150 @@ -46107,6 +51249,7 @@ - annotation: !!omap - ec-code: 4.2.1.- - pmid: 15387819 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2151 @@ -46126,6 +51269,7 @@ - annotation: !!omap - ec-code: 1.3.1.104 - pmid: 11509667 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2152 @@ -46145,6 +51289,7 @@ - annotation: !!omap - ec-code: 1.3.1.104 - pmid: 11509667 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2153 @@ -46164,6 +51309,7 @@ - annotation: !!omap - ec-code: 1.3.1.104 - pmid: 11509667 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2154 @@ -46186,6 +51332,7 @@ - annotation: !!omap - ec-code: 2.3.1.199 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2155 @@ -46208,6 +51355,7 @@ - annotation: !!omap - ec-code: 2.3.1.199 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2156 @@ -46230,6 +51378,7 @@ - annotation: !!omap - ec-code: 2.3.1.199 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2157 @@ -46252,6 +51401,7 @@ - annotation: !!omap - ec-code: 2.3.1.199 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2158 @@ -46274,6 +51424,7 @@ - annotation: !!omap - ec-code: 2.3.1.199 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2159 @@ -46296,6 +51447,7 @@ - annotation: !!omap - ec-code: 2.3.1.199 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2160 @@ -46318,6 +51470,7 @@ - annotation: !!omap - ec-code: 2.3.1.199 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2161 @@ -46339,6 +51492,7 @@ - annotation: !!omap - ec-code: 1.1.1.330 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2162 @@ -46360,6 +51514,7 @@ - annotation: !!omap - ec-code: 1.1.1.330 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2163 @@ -46381,6 +51536,7 @@ - annotation: !!omap - ec-code: 1.1.1.330 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2164 @@ -46402,6 +51558,7 @@ - annotation: !!omap - ec-code: 1.1.1.330 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2165 @@ -46423,6 +51580,7 @@ - annotation: !!omap - ec-code: 1.1.1.330 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2166 @@ -46444,6 +51602,7 @@ - annotation: !!omap - ec-code: 1.1.1.330 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2167 @@ -46465,6 +51624,7 @@ - annotation: !!omap - ec-code: 1.1.1.330 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2168 @@ -46484,6 +51644,7 @@ - annotation: !!omap - ec-code: 4.2.1.134 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2169 @@ -46503,6 +51664,7 @@ - annotation: !!omap - ec-code: 4.2.1.134 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2170 @@ -46522,6 +51684,7 @@ - annotation: !!omap - ec-code: 4.2.1.134 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2171 @@ -46541,6 +51704,7 @@ - annotation: !!omap - ec-code: 4.2.1.134 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2172 @@ -46560,6 +51724,7 @@ - annotation: !!omap - ec-code: 4.2.1.134 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2173 @@ -46579,6 +51744,7 @@ - annotation: !!omap - ec-code: 4.2.1.134 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2174 @@ -46598,6 +51764,7 @@ - annotation: !!omap - ec-code: 4.2.1.134 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2175 @@ -46619,6 +51786,7 @@ - annotation: !!omap - ec-code: 1.3.1.93 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2176 @@ -46640,6 +51808,7 @@ - annotation: !!omap - ec-code: 1.3.1.93 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2177 @@ -46661,6 +51830,7 @@ - annotation: !!omap - ec-code: 1.3.1.93 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2178 @@ -46682,6 +51852,7 @@ - annotation: !!omap - ec-code: 1.3.1.93 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2179 @@ -46703,6 +51874,7 @@ - annotation: !!omap - ec-code: 1.3.1.93 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2180 @@ -46724,6 +51896,7 @@ - annotation: !!omap - ec-code: 1.3.1.93 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2181 @@ -46745,6 +51918,7 @@ - annotation: !!omap - ec-code: 1.3.1.93 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2182 @@ -46766,6 +51940,7 @@ - annotation: !!omap - ec-code: 1.14.19.1 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2183 @@ -46787,6 +51962,7 @@ - annotation: !!omap - ec-code: 1.14.19.1 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2184 @@ -46796,6 +51972,8 @@ - s_1250: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2185 @@ -46805,6 +51983,8 @@ - s_0597: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2186 @@ -46814,6 +51994,8 @@ - s_1067: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2187 @@ -46822,6 +52004,8 @@ - s_2822: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2188 - name: hexanoate exchange @@ -46829,6 +52013,8 @@ - s_2824: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2189 - name: oleate exchange @@ -46836,6 +52022,8 @@ - s_2826: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2190 - name: butyrate (n-C4:0) transport @@ -46844,6 +52032,8 @@ - s_2828: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2191 @@ -46853,6 +52043,8 @@ - s_2829: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2192 @@ -46862,6 +52054,8 @@ - s_2826: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2193 @@ -46870,6 +52064,8 @@ - s_1163: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_2194 - name: fatty-acid--CoA ligase (dodecanoate), ER membrane @@ -46891,6 +52087,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2195 @@ -46913,6 +52110,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2196 @@ -46935,6 +52133,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2197 @@ -46957,6 +52156,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2198 @@ -46979,6 +52179,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2199 @@ -47001,6 +52202,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2200 @@ -47023,6 +52225,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2201 @@ -47045,6 +52248,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2202 @@ -47067,6 +52271,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2203 @@ -47089,6 +52294,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2204 @@ -47111,6 +52317,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2205 @@ -47133,6 +52340,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2206 @@ -47155,6 +52363,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2207 @@ -47177,6 +52386,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2208 @@ -47199,6 +52409,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2209 @@ -47221,6 +52432,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2210 @@ -47243,6 +52455,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2211 @@ -47265,6 +52478,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2212 @@ -47287,6 +52501,7 @@ - annotation: !!omap - ec-code: 6.2.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2213 @@ -47303,6 +52518,7 @@ - gene_reaction_rule: YBR041W - annotation: !!omap - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2214 @@ -47319,6 +52535,7 @@ - gene_reaction_rule: YBR041W - annotation: !!omap - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2215 @@ -47335,6 +52552,7 @@ - gene_reaction_rule: YBR041W - annotation: !!omap - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2216 @@ -47351,6 +52569,7 @@ - gene_reaction_rule: YBR041W - annotation: !!omap - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2217 @@ -47367,6 +52586,7 @@ - gene_reaction_rule: YBR041W - annotation: !!omap - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2218 @@ -47383,6 +52603,7 @@ - gene_reaction_rule: YBR041W - annotation: !!omap - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2219 @@ -47403,6 +52624,7 @@ - sce04146 Peroxisome - annotation: !!omap - pmid: 17010456 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2220 @@ -47423,6 +52645,7 @@ - sce04146 Peroxisome - annotation: !!omap - pmid: 17010456 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2221 @@ -47443,6 +52666,7 @@ - sce04146 Peroxisome - annotation: !!omap - pmid: 17010456 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2222 @@ -47463,6 +52687,7 @@ - sce04146 Peroxisome - annotation: !!omap - pmid: 17010456 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2223 @@ -47483,6 +52708,7 @@ - sce04146 Peroxisome - annotation: !!omap - pmid: 17010456 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2224 @@ -47503,6 +52729,7 @@ - sce04146 Peroxisome - annotation: !!omap - pmid: 17010456 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2225 @@ -47523,6 +52750,7 @@ - sce04146 Peroxisome - annotation: !!omap - pmid: 17010456 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2226 @@ -47543,6 +52771,7 @@ - sce04146 Peroxisome - annotation: !!omap - pmid: 17010456 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2227 @@ -47563,6 +52792,7 @@ - sce04146 Peroxisome - annotation: !!omap - pmid: 17010456 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2228 @@ -47583,6 +52813,7 @@ - sce04146 Peroxisome - annotation: !!omap - pmid: 17010456 + - sbo: SBO:0000655 - confidence_score: 3 - !!omap - id: r_2229 @@ -47592,6 +52823,8 @@ - s_2882: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2230 @@ -47601,6 +52834,8 @@ - s_2883: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2231 @@ -47610,6 +52845,8 @@ - s_2855: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_2232 @@ -47630,6 +52867,7 @@ - annotation: !!omap - ec-code: 3.1.2.2 - pmid: 16490786 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2233 @@ -47650,6 +52888,7 @@ - annotation: !!omap - ec-code: 3.1.2.2 - pmid: 16490786 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2234 @@ -47670,6 +52909,7 @@ - annotation: !!omap - ec-code: 3.1.2.2 - pmid: 16490786 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2235 @@ -47690,6 +52930,7 @@ - annotation: !!omap - ec-code: 3.1.2.2 - pmid: 16490786 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2236 @@ -47711,6 +52952,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2237 @@ -47732,6 +52974,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2238 @@ -47753,6 +52996,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2239 @@ -47774,6 +53018,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2240 @@ -47795,6 +53040,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2241 @@ -47816,6 +53062,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2242 @@ -47837,6 +53084,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2243 @@ -47858,6 +53106,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2244 @@ -47879,6 +53128,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2245 @@ -47900,6 +53150,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2246 @@ -47921,6 +53172,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2247 @@ -47942,6 +53194,7 @@ - annotation: !!omap - ec-code: 1.3.3.6 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2248 @@ -47958,6 +53211,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2249 @@ -47974,6 +53228,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2250 @@ -47990,6 +53245,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2251 @@ -48006,6 +53262,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2252 @@ -48022,6 +53279,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2253 @@ -48038,6 +53296,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2254 @@ -48054,6 +53313,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2255 @@ -48070,6 +53330,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2256 @@ -48086,6 +53347,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2257 @@ -48102,6 +53364,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2258 @@ -48118,6 +53381,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2259 @@ -48134,6 +53398,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2260 @@ -48150,6 +53415,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2261 @@ -48166,6 +53432,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2262 @@ -48182,6 +53449,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2263 @@ -48198,6 +53466,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2264 @@ -48214,6 +53483,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2265 @@ -48230,6 +53500,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2266 @@ -48248,6 +53519,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2267 @@ -48266,6 +53538,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2268 @@ -48284,6 +53557,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2269 @@ -48302,6 +53576,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2270 @@ -48320,6 +53595,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2271 @@ -48338,6 +53614,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2272 @@ -48356,6 +53633,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2273 @@ -48374,6 +53652,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2274 @@ -48392,6 +53671,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2275 @@ -48410,6 +53690,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2276 @@ -48428,6 +53709,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2277 @@ -48446,6 +53728,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2278 @@ -48464,6 +53747,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2279 @@ -48482,6 +53766,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2280 @@ -48500,6 +53785,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2281 @@ -48518,6 +53804,7 @@ - 1.1.1.n12 - 4.2.1.119 - pmid: 12697341 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - 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!!omap - id: r_2320 @@ -49262,6 +54585,7 @@ - 2.3.1.15 - 2.3.1.42 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2321 @@ -49283,6 +54607,7 @@ - 2.3.1.15 - 2.3.1.42 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2322 @@ -49304,6 +54629,7 @@ - 2.3.1.15 - 2.3.1.42 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2323 @@ -49325,6 +54651,7 @@ - 2.3.1.15 - 2.3.1.42 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2324 @@ -49342,6 +54669,7 @@ - annotation: !!omap - ec-code: 1.1.1.101 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2325 @@ -49359,6 +54687,7 @@ - annotation: !!omap - ec-code: 1.1.1.101 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2326 @@ -49376,6 +54705,7 @@ - annotation: !!omap - ec-code: 1.1.1.101 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2327 @@ -49393,6 +54723,7 @@ - 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2.3.1.51 - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2343 @@ -49717,6 +55063,7 @@ - 2.3.1.51 - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2344 @@ -49736,6 +55083,7 @@ - annotation: !!omap - ec-code: 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2345 @@ -49755,6 +55103,7 @@ - annotation: !!omap - ec-code: 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2346 @@ -49774,6 +55123,7 @@ - annotation: !!omap - ec-code: 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2347 @@ -49793,6 +55143,7 @@ - annotation: !!omap - ec-code: 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2348 @@ -49812,6 +55163,7 @@ - annotation: !!omap - ec-code: 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2349 @@ -49831,6 +55183,7 @@ - annotation: !!omap - 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!!omap - id: r_2357 @@ -49995,6 +55355,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2358 @@ -50016,6 +55377,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2359 @@ -50037,6 +55399,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2360 @@ -50054,6 +55417,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2361 @@ -50071,6 +55435,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2362 @@ -50088,6 +55453,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2363 @@ -50105,6 +55471,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2364 @@ -50122,6 +55489,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - 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!!omap - id: r_2373 @@ -50299,6 +55675,7 @@ - 2.3.1.22 - 2.3.1.26 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2374 @@ -50320,6 +55697,7 @@ - 2.3.1.22 - 2.3.1.26 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2375 @@ -50341,6 +55719,7 @@ - 2.3.1.22 - 2.3.1.26 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2376 @@ -50362,6 +55741,7 @@ - 2.3.1.22 - 2.3.1.26 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2377 @@ -50383,6 +55763,7 @@ - 2.3.1.22 - 2.3.1.26 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2378 @@ -50404,6 +55785,7 @@ - 2.3.1.22 - 2.3.1.26 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2379 @@ -50425,6 +55807,7 @@ - 2.3.1.22 - 2.3.1.26 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2380 @@ -50446,6 +55829,7 @@ - 2.3.1.22 - 2.3.1.26 - pmid: 22345606 + - sbo: SBO:0000176 - 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2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2413 @@ -51097,6 +56513,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2414 @@ -51115,6 +56532,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2415 @@ -51133,6 +56551,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2416 @@ -51151,6 +56570,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2417 @@ -51169,6 +56589,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2418 @@ -51187,6 +56608,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2419 @@ -51205,6 +56627,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2420 @@ -51223,6 +56646,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2421 @@ -51241,6 +56665,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2422 @@ -51259,6 +56684,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2423 @@ -51277,6 +56703,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2424 @@ -51295,6 +56722,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2425 @@ -51313,6 +56741,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2426 @@ -51331,6 +56760,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2427 @@ -51349,6 +56779,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2428 @@ -51367,6 +56798,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2429 @@ -51385,6 +56817,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2430 @@ -51403,6 +56836,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2431 @@ -51421,6 +56855,7 @@ - 2.3.1.20 - 2.3.1.22 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2432 @@ -51441,6 +56876,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2433 @@ -51461,6 +56897,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2434 @@ -51481,6 +56918,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2435 @@ -51501,6 +56939,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2436 @@ -51521,6 +56960,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2437 @@ -51541,6 +56981,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2438 @@ -51561,6 +57002,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2439 @@ -51581,6 +57023,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2440 @@ -51601,6 +57044,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2441 @@ -51621,6 +57065,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2442 @@ -51641,6 +57086,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2443 @@ -51661,6 +57107,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2444 @@ -51681,6 +57128,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2445 @@ -51701,6 +57149,7 @@ - annotation: !!omap - ec-code: 2.7.7.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2446 @@ -51721,6 +57170,7 @@ - annotation: !!omap - ec-code: 2.7.8.8 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2447 @@ -51741,6 +57191,7 @@ - annotation: !!omap - ec-code: 2.7.8.8 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2448 @@ -51761,6 +57212,7 @@ - annotation: !!omap - ec-code: 2.7.8.8 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2449 @@ -51781,6 +57233,7 @@ - annotation: !!omap - ec-code: 2.7.8.8 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2450 @@ -51801,6 +57254,7 @@ - annotation: !!omap - ec-code: 2.7.8.8 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2451 @@ -51821,6 +57275,7 @@ - annotation: !!omap - ec-code: 2.7.8.8 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2452 @@ -51841,6 +57296,7 @@ - annotation: !!omap - ec-code: 2.7.8.8 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2453 @@ -51861,6 +57317,7 @@ - annotation: !!omap - ec-code: 2.7.8.8 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2454 @@ -51881,6 +57338,7 @@ - annotation: !!omap - ec-code: 2.7.8.11 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2455 @@ -51901,6 +57359,7 @@ - annotation: !!omap - ec-code: 2.7.8.11 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2456 @@ -51921,6 +57380,7 @@ - annotation: !!omap - ec-code: 2.7.8.11 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2457 @@ -51941,6 +57401,7 @@ - annotation: !!omap - ec-code: 2.7.8.11 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2458 @@ -51961,6 +57422,7 @@ - annotation: !!omap - ec-code: 2.7.8.11 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2459 @@ -51981,6 +57443,7 @@ - annotation: !!omap - ec-code: 2.7.8.11 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2460 @@ -52001,6 +57464,7 @@ - annotation: !!omap - ec-code: 2.7.8.11 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2461 @@ -52021,6 +57485,7 @@ - annotation: !!omap - ec-code: 2.7.8.11 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2462 @@ -52036,6 +57501,7 @@ - annotation: !!omap - ec-code: 2.3.-.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2463 @@ -52051,6 +57517,7 @@ - annotation: !!omap - ec-code: 2.3.-.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2464 @@ -52069,6 +57536,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2465 @@ -52087,6 +57555,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2466 @@ -52105,6 +57574,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2467 @@ -52123,6 +57593,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2468 @@ -52141,6 +57612,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2469 @@ -52159,6 +57631,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2470 @@ -52177,6 +57650,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2471 @@ -52195,6 +57669,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2472 @@ -52213,6 +57688,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2473 @@ -52231,6 +57707,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2474 @@ -52249,6 +57726,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2475 @@ -52267,6 +57745,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2476 @@ -52285,6 +57764,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2477 @@ -52303,6 +57783,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2478 @@ -52321,6 +57802,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2479 @@ -52339,6 +57821,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2480 @@ -52357,6 +57840,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2481 @@ -52375,6 +57859,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2482 @@ -52393,6 +57878,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2483 @@ -52411,6 +57897,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2484 @@ -52429,6 +57916,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2485 @@ -52447,6 +57935,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2486 @@ -52465,6 +57954,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2487 @@ -52483,6 +57973,7 @@ - annotation: !!omap - ec-code: 4.1.1.65 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2488 @@ -52504,6 +57995,7 @@ - 2.1.1.17 - 2.1.1.71 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2489 @@ -52525,6 +58017,7 @@ - 2.1.1.17 - 2.1.1.71 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2490 @@ -52546,6 +58039,7 @@ - 2.1.1.17 - 2.1.1.71 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2491 @@ -52567,6 +58061,7 @@ - 2.1.1.17 - 2.1.1.71 - pmid: 22345606 + - 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confidence_score: 3 - !!omap - id: r_2515 @@ -53063,6 +58581,7 @@ - annotation: !!omap - ec-code: 2.7.1.174 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2516 @@ -53082,6 +58601,7 @@ - annotation: !!omap - ec-code: 2.7.1.174 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2517 @@ -53101,6 +58621,7 @@ - annotation: !!omap - ec-code: 2.7.1.174 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2518 @@ -53120,6 +58641,7 @@ - annotation: !!omap - ec-code: 2.7.1.174 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2519 @@ -53139,6 +58661,7 @@ - annotation: !!omap - ec-code: 2.7.1.174 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2520 @@ -53161,6 +58684,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2521 @@ -53183,6 +58707,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2522 @@ -53205,6 +58730,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2523 @@ -53227,6 +58753,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2524 @@ -53249,6 +58776,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2525 @@ -53271,6 +58799,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2526 @@ -53293,6 +58822,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2527 @@ -53315,6 +58845,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2528 @@ -53337,6 +58868,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2529 @@ -53359,6 +58891,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2530 @@ -53381,6 +58914,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2531 @@ -53403,6 +58937,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2532 @@ -53425,6 +58960,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2533 @@ -53447,6 +58983,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2534 @@ -53469,6 +59006,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2535 @@ -53491,6 +59029,7 @@ - 2.7.8.1 - 2.7.8.2 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2536 @@ -53508,6 +59047,7 @@ - annotation: !!omap - ec-code: 2.7.8.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2537 @@ -53525,6 +59065,7 @@ - annotation: !!omap - ec-code: 2.7.8.5 - pmid: 22345606 + - 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pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2545 @@ -53657,6 +59205,7 @@ - annotation: !!omap - ec-code: 3.1.3.27 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2546 @@ -53673,6 +59222,7 @@ - annotation: !!omap - ec-code: 3.1.3.27 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2547 @@ -53689,6 +59239,7 @@ - annotation: !!omap - ec-code: 3.1.3.27 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2548 @@ -53706,6 +59257,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2549 @@ -53723,6 +59275,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2550 @@ -53740,6 +59293,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2551 @@ -53757,6 +59311,7 @@ - annotation: !!omap - 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annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2559 @@ -53893,6 +59455,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2560 @@ -53910,6 +59473,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2561 @@ -53927,6 +59491,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2562 @@ -53944,6 +59509,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2563 @@ -53961,6 +59527,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2564 @@ -53978,6 +59545,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2565 @@ -53995,6 +59563,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2566 @@ -54012,6 +59581,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2567 @@ -54029,6 +59599,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2568 @@ -54046,6 +59617,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2569 @@ -54063,6 +59635,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2570 @@ -54080,6 +59653,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2571 @@ -54097,6 +59671,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2572 @@ -54114,6 +59689,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2573 @@ -54131,6 +59707,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2574 @@ -54148,6 +59725,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2575 @@ -54165,6 +59743,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2576 @@ -54182,6 +59761,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2577 @@ -54199,6 +59779,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2578 @@ -54216,6 +59797,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2579 @@ -54233,6 +59815,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2580 @@ -54250,6 +59833,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2581 @@ -54267,6 +59851,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2582 @@ -54284,6 +59869,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2583 @@ -54301,6 +59887,7 @@ - annotation: !!omap - ec-code: 2.7.8.41 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2584 @@ -54318,6 +59905,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2585 @@ -54335,6 +59923,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2586 @@ -54352,6 +59941,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2587 @@ -54369,6 +59959,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2588 @@ -54386,6 +59977,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2589 @@ -54403,6 +59995,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2590 @@ -54420,6 +60013,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2591 @@ -54437,6 +60031,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2592 @@ -54454,6 +60049,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2593 @@ -54471,6 +60067,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2594 @@ -54488,6 +60085,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2595 @@ -54505,6 +60103,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2596 @@ -54522,6 +60121,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2597 @@ -54539,6 +60139,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2598 @@ -54556,6 +60157,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2599 @@ -54573,6 +60175,7 @@ - annotation: !!omap - ec-code: 3.5.1.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2600 @@ -54590,6 +60193,7 @@ - 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annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2727 @@ -56641,6 +62371,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2728 @@ -56657,6 +62388,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2729 @@ -56673,6 +62405,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2730 @@ -56689,6 +62422,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2731 @@ -56705,6 +62439,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2732 @@ -56721,6 +62456,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2733 @@ -56737,6 +62473,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2734 @@ -56753,6 +62490,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2735 @@ -56769,6 +62507,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2736 @@ -56785,6 +62524,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2737 @@ -56801,6 +62541,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2738 @@ -56817,6 +62558,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2739 @@ -56833,6 +62575,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2740 @@ -56849,6 +62592,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2741 @@ -56865,6 +62609,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2742 @@ -56881,6 +62626,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2743 @@ -56897,6 +62643,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2744 @@ -56913,6 +62660,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2745 @@ -56929,6 +62677,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2746 @@ -56945,6 +62694,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2747 @@ -56961,6 +62711,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2748 @@ -56977,6 +62728,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2749 @@ -56993,6 +62745,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2750 @@ -57009,6 +62762,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2751 @@ -57025,6 +62779,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2752 @@ -57041,6 +62796,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2753 @@ -57057,6 +62813,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2754 @@ -57073,6 +62830,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2755 @@ -57089,6 +62847,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2756 @@ -57105,6 +62864,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2757 @@ -57121,6 +62881,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2758 @@ -57137,6 +62898,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2759 @@ -57153,6 +62915,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2760 @@ -57169,6 +62932,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2761 @@ -57185,6 +62949,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2762 @@ -57201,6 +62966,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2763 @@ -57217,6 +62983,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2764 @@ -57233,6 +63000,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2765 @@ -57249,6 +63017,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2766 @@ -57265,6 +63034,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2767 @@ -57281,6 +63051,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2768 @@ -57297,6 +63068,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2769 @@ -57313,6 +63085,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2770 @@ -57329,6 +63102,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2771 @@ -57345,6 +63119,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2772 @@ -57361,6 +63136,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2773 @@ -57377,6 +63153,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2774 @@ -57393,6 +63170,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2775 @@ -57409,6 +63187,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2776 @@ -57425,6 +63204,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2777 @@ -57441,6 +63221,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2778 @@ -57457,6 +63238,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2779 @@ -57473,6 +63255,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2780 @@ -57489,6 +63272,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2781 @@ -57505,6 +63289,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2782 @@ -57521,6 +63306,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2783 @@ -57537,6 +63323,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2784 @@ -57553,6 +63340,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2785 @@ -57569,6 +63357,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2786 @@ -57585,6 +63374,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2787 @@ -57601,6 +63391,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2788 @@ -57617,6 +63408,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2789 @@ -57633,6 +63425,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2790 @@ -57649,6 +63442,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2791 @@ -57665,6 +63459,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2792 @@ -57681,6 +63476,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2793 @@ -57697,6 +63493,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2794 @@ -57713,6 +63510,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2795 @@ -57729,6 +63527,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2796 @@ -57745,6 +63544,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2797 @@ -57761,6 +63561,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2798 @@ -57777,6 +63578,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2799 @@ -57793,6 +63595,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2800 @@ -57809,6 +63612,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2801 @@ -57825,6 +63629,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2802 @@ -57841,6 +63646,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2803 @@ -57857,6 +63663,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2804 @@ -57873,6 +63680,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2805 @@ -57889,6 +63697,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2806 @@ -57905,6 +63714,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2807 @@ -57921,6 +63731,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2808 @@ -57937,6 +63748,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2809 @@ -57953,6 +63765,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2810 @@ -57969,6 +63782,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2811 @@ -57985,6 +63799,7 @@ - annotation: !!omap - ec-code: 2.3.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2812 @@ -57996,6 +63811,8 @@ - s_3321: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2813 @@ -58007,6 +63824,8 @@ - s_3322: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2814 @@ -58018,6 +63837,8 @@ - s_3321: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2815 @@ -58029,6 +63850,8 @@ - s_3322: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2816 @@ -58040,6 +63863,8 @@ - s_3321: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2817 @@ -58051,6 +63876,8 @@ - s_3322: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2818 @@ -58062,6 +63889,8 @@ - s_3321: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2819 @@ -58073,6 +63902,8 @@ - s_3322: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_2820 @@ -58093,6 +63924,7 @@ - annotation: !!omap - ec-code: 2.7.1.67 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2821 @@ -58113,6 +63945,7 @@ - annotation: !!omap - ec-code: 2.7.1.67 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2822 @@ -58133,6 +63966,7 @@ - annotation: !!omap - ec-code: 2.7.1.67 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_2823 @@ -58153,6 +63987,7 @@ - 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annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3058 @@ -62070,6 +68129,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3059 @@ -62087,6 +68147,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3060 @@ -62104,6 +68165,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3061 @@ -62121,6 +68183,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3062 @@ -62138,6 +68201,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3063 @@ -62155,6 +68219,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3064 @@ -62172,6 +68237,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3065 @@ -62189,6 +68255,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3066 @@ -62206,6 +68273,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3067 @@ -62223,6 +68291,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3068 @@ -62240,6 +68309,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3069 @@ -62257,6 +68327,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3070 @@ -62274,6 +68345,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3071 @@ -62291,6 +68363,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3072 @@ -62308,6 +68381,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3073 @@ -62325,6 +68399,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3074 @@ -62342,6 +68417,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3075 @@ -62359,6 +68435,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3076 @@ -62376,6 +68453,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3077 @@ -62393,6 +68471,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3078 @@ -62410,6 +68489,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3079 @@ -62427,6 +68507,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3080 @@ -62444,6 +68525,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3081 @@ -62461,6 +68543,7 @@ - annotation: !!omap - ec-code: 3.1.1.5 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3082 @@ -62481,6 +68564,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3083 @@ -62501,6 +68585,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3084 @@ -62521,6 +68606,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3085 @@ -62541,6 +68627,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3086 @@ -62561,6 +68648,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3087 @@ -62581,6 +68669,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3088 @@ -62601,6 +68690,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3089 @@ -62621,6 +68711,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3090 @@ -62641,6 +68732,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3091 @@ -62661,6 +68753,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3092 @@ -62681,6 +68774,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3093 @@ -62701,6 +68795,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3094 @@ -62721,6 +68816,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3095 @@ -62741,6 +68837,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3096 @@ -62761,6 +68858,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3097 @@ -62781,6 +68879,7 @@ - annotation: !!omap - ec-code: 3.1.4.11 - pmid: 17382260 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3098 @@ -62798,6 +68897,7 @@ - annotation: !!omap - ec-code: 3.1.4.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3099 @@ -62815,6 +68915,7 @@ - annotation: !!omap - ec-code: 3.1.4.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3100 @@ -62832,6 +68933,7 @@ - annotation: !!omap - ec-code: 3.1.4.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3101 @@ -62849,6 +68951,7 @@ - annotation: !!omap - ec-code: 3.1.4.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3102 @@ -62866,6 +68969,7 @@ - annotation: !!omap - ec-code: 3.1.4.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3103 @@ -62883,6 +68987,7 @@ - annotation: !!omap - ec-code: 3.1.4.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3104 @@ -62903,6 +69008,7 @@ - annotation: !!omap - ec-code: 3.1.4.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3105 @@ -62923,6 +69029,7 @@ - annotation: !!omap - ec-code: 3.1.4.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3106 @@ -62943,6 +69050,7 @@ - annotation: !!omap - ec-code: 3.1.4.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3107 @@ -62963,6 +69071,7 @@ - annotation: !!omap - ec-code: 3.1.4.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3108 @@ -62983,6 +69092,7 @@ - annotation: !!omap - ec-code: 3.1.4.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3109 @@ -63003,6 +69113,7 @@ - annotation: !!omap - ec-code: 3.1.4.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3110 @@ -63023,6 +69134,7 @@ - annotation: !!omap - ec-code: 3.1.4.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3111 @@ -63043,6 +69155,7 @@ - annotation: !!omap - ec-code: 3.1.4.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3112 @@ -63063,6 +69176,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3113 @@ -63083,6 +69197,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3114 @@ -63103,6 +69218,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3115 @@ -63123,6 +69239,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3116 @@ -63143,6 +69260,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3117 @@ -63163,6 +69281,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3118 @@ -63183,6 +69302,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3119 @@ -63203,6 +69323,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3120 @@ -63225,6 +69346,7 @@ - 3.1.3.36 - 3.1.3.64 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3121 @@ -63247,6 +69369,7 @@ - 3.1.3.36 - 3.1.3.64 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3122 @@ -63269,6 +69392,7 @@ - 3.1.3.36 - 3.1.3.64 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3123 @@ -63291,6 +69415,7 @@ - 3.1.3.36 - 3.1.3.64 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3124 @@ -63313,6 +69438,7 @@ - 3.1.3.36 - 3.1.3.64 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3125 @@ -63335,6 +69461,7 @@ - 3.1.3.36 - 3.1.3.64 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3126 @@ -63357,6 +69484,7 @@ - 3.1.3.36 - 3.1.3.64 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3127 @@ -63379,6 +69507,7 @@ - 3.1.3.36 - 3.1.3.64 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3128 @@ -63397,6 +69526,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3129 @@ -63415,6 +69545,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3130 @@ -63433,6 +69564,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3131 @@ -63451,6 +69583,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3132 @@ -63469,6 +69602,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3133 @@ -63487,6 +69621,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3134 @@ -63505,6 +69640,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3135 @@ -63523,6 +69659,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3136 @@ -63541,6 +69678,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3137 @@ -63559,6 +69697,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3138 @@ -63577,6 +69716,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3139 @@ -63595,6 +69735,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3140 @@ -63613,6 +69754,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3141 @@ -63631,6 +69773,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3142 @@ -63649,6 +69792,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3143 @@ -63667,6 +69811,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3144 @@ -63687,6 +69832,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3145 @@ -63707,6 +69853,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3146 @@ -63727,6 +69874,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3147 @@ -63747,6 +69895,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3148 @@ -63767,6 +69916,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3149 @@ -63787,6 +69937,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3150 @@ -63807,6 +69958,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3151 @@ -63827,6 +69979,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3152 @@ -63847,6 +70000,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3153 @@ -63867,6 +70021,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3154 @@ -63887,6 +70042,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3155 @@ -63907,6 +70063,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3156 @@ -63927,6 +70084,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3157 @@ -63947,6 +70105,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3158 @@ -63967,6 +70126,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3159 @@ -63987,6 +70147,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3160 @@ -64005,6 +70166,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3161 @@ -64023,6 +70185,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3162 @@ -64041,6 +70204,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3163 @@ -64059,6 +70223,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3164 @@ -64077,6 +70242,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3165 @@ -64095,6 +70261,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3166 @@ -64113,6 +70280,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3167 @@ -64131,6 +70299,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3168 @@ -64149,6 +70318,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3169 @@ -64167,6 +70337,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3170 @@ -64185,6 +70356,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3171 @@ -64203,6 +70375,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3172 @@ -64221,6 +70394,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3173 @@ -64239,6 +70413,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3174 @@ -64257,6 +70432,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3175 @@ -64275,6 +70451,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3176 @@ -64295,6 +70472,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3177 @@ -64315,6 +70493,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3178 @@ -64335,6 +70514,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3179 @@ -64355,6 +70535,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3180 @@ -64375,6 +70556,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3181 @@ -64395,6 +70577,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3182 @@ -64415,6 +70598,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3183 @@ -64435,6 +70619,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3184 @@ -64455,6 +70640,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3185 @@ -64475,6 +70661,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3186 @@ -64495,6 +70682,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3187 @@ -64515,6 +70703,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3188 @@ -64535,6 +70724,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3189 @@ -64555,6 +70745,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3190 @@ -64575,6 +70766,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3191 @@ -64595,6 +70787,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3192 @@ -64615,6 +70808,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3193 @@ -64635,6 +70829,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3194 @@ -64655,6 +70850,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3195 @@ -64675,6 +70871,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3196 @@ -64695,6 +70892,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3197 @@ -64715,6 +70913,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3198 @@ -64735,6 +70934,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3199 @@ -64755,6 +70955,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3200 @@ -64775,6 +70976,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3201 @@ -64795,6 +70997,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3202 @@ -64815,6 +71018,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3203 @@ -64835,6 +71039,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3204 @@ -64855,6 +71060,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3205 @@ -64875,6 +71081,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3206 @@ -64895,6 +71102,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3207 @@ -64915,6 +71123,7 @@ - 3.1.3.- - 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3208 @@ -64933,6 +71142,7 @@ - annotation: !!omap - ec-code: 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3209 @@ -64951,6 +71161,7 @@ - annotation: !!omap - ec-code: 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3210 @@ -64969,6 +71180,7 @@ - annotation: !!omap - ec-code: 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3211 @@ -64987,6 +71199,7 @@ - annotation: !!omap - ec-code: 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3212 @@ -65005,6 +71218,7 @@ - annotation: !!omap - ec-code: 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3213 @@ -65023,6 +71237,7 @@ - annotation: !!omap - ec-code: 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3214 @@ -65041,6 +71256,7 @@ - annotation: !!omap - ec-code: 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3215 @@ -65059,6 +71275,7 @@ - annotation: !!omap - ec-code: 3.1.3.36 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3216 @@ -65074,6 +71291,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3217 @@ -65089,6 +71307,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3218 @@ -65104,6 +71323,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3219 @@ -65119,6 +71339,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3220 @@ -65134,6 +71355,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3221 @@ -65149,6 +71371,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3222 @@ -65164,6 +71387,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3223 @@ -65179,6 +71403,7 @@ - annotation: !!omap - ec-code: 3.1.3.- - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3224 @@ -65201,6 +71426,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3225 @@ -65223,6 +71449,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3226 @@ -65245,6 +71472,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3227 @@ -65267,6 +71495,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3228 @@ -65289,6 +71518,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3229 @@ -65311,6 +71541,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3230 @@ -65333,6 +71564,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3231 @@ -65355,6 +71587,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3232 @@ -65373,6 +71606,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3233 @@ -65391,6 +71625,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3234 @@ -65409,6 +71644,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3235 @@ -65427,6 +71663,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3236 @@ -65445,6 +71682,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3237 @@ -65463,6 +71701,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3238 @@ -65481,6 +71720,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3239 @@ -65499,6 +71739,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3240 @@ -65513,6 +71754,7 @@ - gene_reaction_rule: YER037W - annotation: !!omap - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3241 @@ -65527,6 +71769,7 @@ - gene_reaction_rule: YER037W - annotation: !!omap - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3242 @@ -65541,6 +71784,7 @@ - gene_reaction_rule: YER037W - annotation: !!omap - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3243 @@ -65555,6 +71799,7 @@ - gene_reaction_rule: YER037W - annotation: !!omap - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3244 @@ -65576,6 +71821,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3245 @@ -65597,6 +71843,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3246 @@ -65618,6 +71865,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3247 @@ -65639,6 +71887,7 @@ - 3.1.3.4 - 3.1.3.81 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3248 @@ -65656,6 +71905,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3249 @@ -65673,6 +71923,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3250 @@ -65690,6 +71941,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3251 @@ -65707,6 +71959,7 @@ - 3.1.3.- - 3.1.3.4 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3252 @@ -65726,6 +71979,7 @@ - pmid: - 16835446 - 14640980 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3253 @@ -65745,6 +71999,7 @@ - pmid: - 16835446 - 14640980 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3254 @@ -65761,6 +72016,7 @@ - annotation: !!omap - ec-code: 3.1.1.13 - pmid: 16835446 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3255 @@ -65777,6 +72033,7 @@ - annotation: !!omap - ec-code: 3.1.1.13 - pmid: 16835446 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3256 @@ -65793,6 +72050,7 @@ - annotation: !!omap - ec-code: 3.1.1.13 - pmid: 16835446 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3257 @@ -65809,6 +72067,7 @@ - annotation: !!omap - ec-code: 3.1.1.13 - pmid: 16835446 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3258 @@ -65825,6 +72084,7 @@ - annotation: !!omap - ec-code: 3.1.1.13 - pmid: 16835446 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3259 @@ -65841,6 +72101,7 @@ - annotation: !!omap - ec-code: 3.1.1.13 - pmid: 16835446 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3260 @@ -65857,6 +72118,7 @@ - annotation: !!omap - ec-code: 3.1.1.13 - pmid: 16835446 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3261 @@ -65873,6 +72135,7 @@ - annotation: !!omap - ec-code: 3.1.1.13 - pmid: 16835446 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3262 @@ -65889,6 +72152,7 @@ - annotation: !!omap - ec-code: 3.1.1.13 - pmid: 15632184 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3263 @@ -65905,6 +72169,7 @@ - annotation: !!omap - ec-code: 3.1.1.13 - pmid: 15632184 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3264 @@ -65928,6 +72193,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3265 @@ -65951,6 +72217,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3266 @@ -65974,6 +72241,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3267 @@ -65997,6 +72265,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3268 @@ -66020,6 +72289,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3269 @@ -66043,6 +72313,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3270 @@ -66066,6 +72337,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3271 @@ -66089,6 +72361,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3272 @@ -66112,6 +72385,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3273 @@ -66135,6 +72409,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3274 @@ -66158,6 +72433,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3275 @@ -66181,6 +72457,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3276 @@ -66204,6 +72481,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3277 @@ -66227,6 +72505,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3278 @@ -66250,6 +72529,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3279 @@ -66273,6 +72553,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3280 @@ -66296,6 +72577,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3281 @@ -66319,6 +72601,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3282 @@ -66342,6 +72625,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3283 @@ -66365,6 +72649,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3284 @@ -66388,6 +72673,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3285 @@ -66411,6 +72697,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3286 @@ -66434,6 +72721,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3287 @@ -66457,6 +72745,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3288 @@ -66480,6 +72769,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3289 @@ -66503,6 +72793,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3290 @@ -66526,6 +72817,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3291 @@ -66549,6 +72841,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3292 @@ -66572,6 +72865,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3293 @@ -66595,6 +72889,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3294 @@ -66618,6 +72913,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3295 @@ -66641,6 +72937,7 @@ - 3.1.1.- - 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3296 @@ -66658,6 +72955,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3297 @@ -66675,6 +72973,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3298 @@ -66692,6 +72991,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3299 @@ -66709,6 +73009,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3300 @@ -66726,6 +73027,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3301 @@ -66743,6 +73045,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3302 @@ -66760,6 +73063,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3303 @@ -66777,6 +73081,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3304 @@ -66794,6 +73099,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3305 @@ -66811,6 +73117,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3306 @@ -66828,6 +73135,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3307 @@ -66845,6 +73153,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3308 @@ -66862,6 +73171,7 @@ - annotation: !!omap - ec-code: 3.1.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3309 @@ -66879,6 +73189,7 @@ - annotation: !!omap - ec-code: 3.1.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3310 @@ -66896,6 +73207,7 @@ - annotation: !!omap - ec-code: 3.1.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3311 @@ -66913,6 +73225,7 @@ - annotation: !!omap - ec-code: 3.1.1.23 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3312 @@ -66929,6 +73242,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 20016004 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3313 @@ -66945,6 +73259,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 20016004 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3314 @@ -66961,6 +73276,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 20016004 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3315 @@ -66977,6 +73293,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 20016004 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3316 @@ -66998,6 +73315,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3317 @@ -67019,6 +73337,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3318 @@ -67040,6 +73359,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3319 @@ -67061,6 +73381,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3320 @@ -67082,6 +73403,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3321 @@ -67103,6 +73425,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3322 @@ -67124,6 +73447,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3323 @@ -67145,6 +73469,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3324 @@ -67166,6 +73491,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3325 @@ -67187,6 +73513,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3326 @@ -67208,6 +73535,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3327 @@ -67229,6 +73557,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3328 @@ -67250,6 +73579,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3329 @@ -67271,6 +73601,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3330 @@ -67292,6 +73623,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3331 @@ -67313,6 +73645,7 @@ - annotation: !!omap - ec-code: 3.1.1.3 - pmid: 22345606 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3332 @@ -67324,6 +73657,8 @@ - s_3624: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3333 @@ -67335,6 +73670,8 @@ - s_3625: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3334 @@ -67346,6 +73683,8 @@ - s_3626: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3335 @@ -67357,6 +73696,8 @@ - s_3627: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3336 @@ -67368,6 +73709,8 @@ - s_3628: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3337 @@ -67379,6 +73722,8 @@ - s_3629: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3338 @@ -67390,6 +73735,8 @@ - s_3630: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3339 @@ -67401,6 +73748,8 @@ - s_3631: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3340 @@ -67412,6 +73761,8 @@ - s_3616: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3341 @@ -67423,6 +73774,8 @@ - s_3617: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3342 @@ -67434,6 +73787,8 @@ - s_3618: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3343 @@ -67445,6 +73800,8 @@ - s_3619: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3344 @@ -67456,6 +73813,8 @@ - s_3620: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3345 @@ -67467,6 +73826,8 @@ - s_3621: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3346 @@ -67478,6 +73839,8 @@ - s_3622: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3347 @@ -67489,6 +73852,8 @@ - s_3623: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_3348 @@ -67506,6 +73871,7 @@ - pmid: - 18296751 - 9368028 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_3349 @@ -67523,6 +73889,7 @@ - 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annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3529 @@ -70407,6 +76974,8 @@ - s_2799: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3530 @@ -70416,6 +76985,8 @@ - s_2800: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3531 @@ -70425,6 +76996,8 @@ - s_2817: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3532 @@ -70434,6 +77007,8 @@ - s_2818: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3533 @@ -70443,6 +77018,8 @@ - s_2820: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3534 @@ -70452,6 +77029,8 @@ - s_2934: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3535 @@ -70461,6 +77040,8 @@ - s_2939: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3536 @@ -70470,6 +77051,8 @@ - s_2834: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3537 @@ -70479,6 +77062,8 @@ - s_2966: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3538 @@ -70488,6 +77073,8 @@ - s_3083: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3539 @@ -70497,6 +77084,8 @@ - s_3215: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3540 @@ -70506,6 +77095,8 @@ - s_3108: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3541 @@ -70515,6 +77106,8 @@ - s_3216: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3542 @@ -70524,6 +77117,8 @@ - s_3217: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3543 @@ -70533,6 +77128,8 @@ - s_2831: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3544 @@ -70542,6 +77139,8 @@ - s_2833: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3545 @@ -70551,6 +77150,8 @@ - s_3107: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3546 @@ -70560,6 +77161,8 @@ - s_3117: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3547 @@ -70569,6 +77172,8 @@ - s_3182: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3548 @@ -70578,6 +77183,8 @@ - s_3183: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3549 @@ -70587,6 +77194,8 @@ - s_3432: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3550 @@ -70596,6 +77205,8 @@ - s_3435: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3551 @@ -70605,6 +77216,8 @@ - s_3438: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3552 @@ -70614,6 +77227,8 @@ - s_3441: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3553 @@ -70623,6 +77238,8 @@ - s_3444: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3554 @@ -70632,6 +77249,8 @@ - s_3497: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3555 @@ -70641,6 +77260,8 @@ - s_3500: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3556 @@ -70650,6 +77271,8 @@ - s_3502: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3557 @@ -70659,6 +77282,8 @@ - s_3504: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3558 @@ -70668,6 +77293,8 @@ - s_3506: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3559 @@ -70677,6 +77304,8 @@ - s_3508: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3560 @@ -70686,6 +77315,8 @@ - s_3510: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3561 @@ -70695,6 +77326,8 @@ - s_3512: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3562 @@ -70704,6 +77337,8 @@ - s_3545: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3563 @@ -70713,6 +77348,8 @@ - s_3547: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3564 @@ -70722,6 +77359,8 @@ - s_3549: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3565 @@ -70731,6 +77370,8 @@ - s_3551: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3566 @@ -70740,6 +77381,8 @@ - s_3553: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3567 @@ -70749,6 +77392,8 @@ - s_3555: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3568 @@ -70758,6 +77403,8 @@ - s_3557: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3569 @@ -70767,6 +77414,8 @@ - s_3559: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3570 @@ -70776,6 +77425,8 @@ - s_3447: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3571 @@ -70785,6 +77436,8 @@ - s_2846: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3572 @@ -70794,6 +77447,8 @@ - s_2848: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3573 @@ -70803,6 +77458,8 @@ - s_2850: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3574 @@ -70812,6 +77469,8 @@ - s_2852: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3575 @@ -70821,6 +77480,8 @@ - s_2843: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3576 @@ -70830,6 +77491,8 @@ - s_2845: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3577 @@ -70839,6 +77502,8 @@ - s_2847: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3578 @@ -70848,6 +77513,8 @@ - s_2877: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3579 @@ -70857,6 +77524,8 @@ - s_2851: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3580 @@ -70866,6 +77535,8 @@ - s_2853: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3581 @@ -70875,6 +77546,8 @@ - s_0769: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3582 @@ -70884,6 +77557,8 @@ - s_0631: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3583 @@ -70893,6 +77568,8 @@ - s_2952: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3584 @@ -70902,6 +77579,8 @@ - s_2953: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3585 @@ -70911,6 +77590,8 @@ - s_2840: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3586 @@ -70920,6 +77601,8 @@ - s_2842: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3587 @@ -70929,6 +77612,8 @@ - s_0635: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3588 @@ -70938,6 +77623,8 @@ - s_3497: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3589 @@ -70947,6 +77634,8 @@ - s_3500: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3590 @@ -70956,6 +77645,8 @@ - s_3502: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3591 @@ -70965,6 +77656,8 @@ - s_3504: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3592 @@ -70974,6 +77667,8 @@ - s_3506: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3593 @@ -70983,6 +77678,8 @@ - s_3508: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3594 @@ -70992,6 +77689,8 @@ - s_3510: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3595 @@ -71001,6 +77700,8 @@ - s_3512: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3596 @@ -71010,6 +77711,8 @@ - s_3657: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3597 @@ -71019,6 +77722,8 @@ - s_3684: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3598 @@ -71028,6 +77733,8 @@ - s_2880: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3599 @@ -71037,6 +77744,8 @@ - s_2874: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3600 @@ -71046,6 +77755,8 @@ - s_2876: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3601 @@ -71055,6 +77766,8 @@ - s_2856: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3602 @@ -71064,6 +77777,8 @@ - s_3324: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3603 @@ -71073,6 +77788,8 @@ - s_0794: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3604 @@ -71082,6 +77799,8 @@ - s_3449: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3605 @@ -71091,6 +77810,8 @@ - s_3536: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3606 @@ -71100,6 +77821,8 @@ - s_1433: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3607 @@ -71109,6 +77832,8 @@ - s_3495: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3608 @@ -71118,6 +77843,8 @@ - s_3463: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3609 @@ -71127,6 +77854,8 @@ - s_3451: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3610 @@ -71136,6 +77865,8 @@ - s_3464: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3611 @@ -71145,6 +77876,8 @@ - s_3459: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3612 @@ -71154,6 +77887,8 @@ - s_2878: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3613 @@ -71163,6 +77898,8 @@ - s_2880: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3614 @@ -71172,6 +77909,8 @@ - s_2865: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3615 @@ -71181,6 +77920,8 @@ - s_2867: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3616 @@ -71190,6 +77931,8 @@ - s_3496: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3617 @@ -71199,6 +77942,8 @@ - s_3499: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3618 @@ -71208,6 +77953,8 @@ - s_3501: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3619 @@ -71217,6 +77964,8 @@ - s_3503: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3620 @@ -71226,6 +77975,8 @@ - s_3505: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3621 @@ -71235,6 +77986,8 @@ - s_3507: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3622 @@ -71244,6 +77997,8 @@ - s_3509: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3623 @@ -71253,6 +78008,8 @@ - s_3511: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3624 @@ -71262,6 +78019,8 @@ - s_3576: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3625 @@ -71271,6 +78030,8 @@ - s_3577: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3626 @@ -71280,6 +78041,8 @@ - s_3578: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3627 @@ -71289,6 +78052,8 @@ - s_3579: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3628 @@ -71298,6 +78063,8 @@ - s_3580: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3629 @@ -71307,6 +78074,8 @@ - s_3581: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3630 @@ -71316,6 +78085,8 @@ - s_3582: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3631 @@ -71325,6 +78096,8 @@ - s_3583: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3632 @@ -71334,6 +78107,8 @@ - s_3496: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3633 @@ -71343,6 +78118,8 @@ - s_3499: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3634 @@ -71352,6 +78129,8 @@ - s_3501: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3635 @@ -71361,6 +78140,8 @@ - s_3503: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3636 @@ -71370,6 +78151,8 @@ - s_3505: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3637 @@ -71379,6 +78162,8 @@ - s_3507: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3638 @@ -71388,6 +78173,8 @@ - s_3509: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3639 @@ -71397,6 +78184,8 @@ - s_3511: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3640 @@ -71406,6 +78195,8 @@ - s_3513: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3641 @@ -71415,6 +78206,8 @@ - s_3514: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3642 @@ -71424,6 +78217,8 @@ - s_3515: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3643 @@ -71433,6 +78228,8 @@ - s_3516: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3644 @@ -71442,6 +78239,8 @@ - s_3517: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3645 @@ -71451,6 +78250,8 @@ - s_3518: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3646 @@ -71460,6 +78261,8 @@ - s_3519: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3647 @@ -71469,6 +78272,8 @@ - s_3520: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3648 @@ -71478,6 +78283,8 @@ - s_2976: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3649 @@ -71487,6 +78294,8 @@ - s_2977: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3650 @@ -71496,6 +78305,8 @@ - s_3164: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3651 @@ -71505,6 +78316,8 @@ - s_3341: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3652 @@ -71514,6 +78327,8 @@ - s_3342: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3653 @@ -71523,6 +78338,8 @@ - s_3165: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3654 @@ -71532,6 +78349,8 @@ - s_3600: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3655 @@ -71541,6 +78360,8 @@ - s_3601: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3656 @@ -71550,6 +78371,8 @@ - s_3602: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3657 @@ -71559,6 +78382,8 @@ - s_3603: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3658 @@ -71568,6 +78393,8 @@ - s_3604: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3659 @@ -71577,6 +78404,8 @@ - s_3605: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3660 @@ -71586,6 +78415,8 @@ - s_3606: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3661 @@ -71595,6 +78426,8 @@ - s_3607: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3662 @@ -71604,6 +78437,8 @@ - s_2994: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3663 @@ -71613,6 +78448,8 @@ - s_2995: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3664 @@ -71622,6 +78459,8 @@ - s_3146: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3665 @@ -71631,6 +78470,8 @@ - s_3147: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3666 @@ -71640,6 +78481,8 @@ - s_3359: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3667 @@ -71649,6 +78492,8 @@ - s_3360: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3668 @@ -71658,6 +78503,8 @@ - s_3226: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3669 @@ -71667,6 +78514,8 @@ - s_3129: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3670 @@ -71676,6 +78525,8 @@ - s_3320: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3671 @@ -71685,6 +78536,8 @@ - s_3322: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3672 @@ -71694,6 +78547,8 @@ - s_3521: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3673 @@ -71703,6 +78558,8 @@ - s_3522: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3674 @@ -71712,6 +78569,8 @@ - s_3523: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3675 @@ -71721,6 +78580,8 @@ - s_3524: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3676 @@ -71730,6 +78591,8 @@ - s_3525: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3677 @@ -71739,6 +78602,8 @@ - s_3526: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3678 @@ -71748,6 +78613,8 @@ - s_3271: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3679 @@ -71757,6 +78624,8 @@ - s_3277: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3680 @@ -71766,6 +78635,8 @@ - s_3321: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3681 @@ -71775,6 +78646,8 @@ - s_2841: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3682 @@ -71784,6 +78657,8 @@ - s_2844: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3683 @@ -71793,6 +78668,8 @@ - s_2873: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3684 @@ -71802,6 +78679,8 @@ - s_2875: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3685 @@ -71811,6 +78690,8 @@ - s_3044: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3686 @@ -71820,6 +78701,8 @@ - s_3059: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3687 @@ -71829,6 +78712,8 @@ - s_3067: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3688 @@ -71838,6 +78723,8 @@ - s_3075: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3689 @@ -71847,6 +78734,8 @@ - s_3048: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3690 @@ -71856,6 +78745,8 @@ - s_3061: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3691 @@ -71865,6 +78756,8 @@ - s_3069: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3692 @@ -71874,6 +78767,8 @@ - s_3077: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3693 @@ -71883,6 +78778,8 @@ - s_3052: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3694 @@ -71892,6 +78789,8 @@ - s_3063: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3695 @@ -71901,6 +78800,8 @@ - s_3071: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3696 @@ -71910,6 +78811,8 @@ - s_3079: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3697 @@ -71919,6 +78822,8 @@ - s_3056: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3698 @@ -71928,6 +78833,8 @@ - s_3065: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3699 @@ -71937,6 +78844,8 @@ - s_3073: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3700 @@ -71946,6 +78855,8 @@ - s_3081: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3701 @@ -71955,6 +78866,8 @@ - s_3046: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3702 @@ -71964,6 +78877,8 @@ - s_3060: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3703 @@ -71973,6 +78888,8 @@ - s_3068: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3704 @@ -71982,6 +78899,8 @@ - s_3076: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3705 @@ -71991,6 +78910,8 @@ - s_3050: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3706 @@ -72000,6 +78921,8 @@ - s_3062: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3707 @@ -72009,6 +78932,8 @@ - s_3070: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3708 @@ -72018,6 +78943,8 @@ - s_3078: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3709 @@ -72027,6 +78954,8 @@ - s_3054: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3710 @@ -72036,6 +78965,8 @@ - s_3064: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3711 @@ -72045,6 +78976,8 @@ - s_3072: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3712 @@ -72054,6 +78987,8 @@ - s_3080: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3713 @@ -72063,6 +78998,8 @@ - s_3058: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3714 @@ -72072,6 +79009,8 @@ - s_3066: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3715 @@ -72081,6 +79020,8 @@ - s_3074: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3716 @@ -72090,6 +79031,8 @@ - s_3082: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3717 @@ -72099,6 +79042,8 @@ - s_3660: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3718 @@ -72108,6 +79053,8 @@ - s_3435: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3719 @@ -72117,6 +79064,8 @@ - s_3665: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3720 @@ -72126,6 +79075,8 @@ - s_3444: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3721 @@ -72135,6 +79086,8 @@ - s_3656: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3722 @@ -72144,6 +79097,8 @@ - s_3658: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3723 @@ -72153,6 +79108,8 @@ - s_3659: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3724 @@ -72162,6 +79119,8 @@ - s_3661: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3725 @@ -72171,6 +79130,8 @@ - s_3662: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3726 @@ -72180,6 +79141,8 @@ - s_3663: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3727 @@ -72189,6 +79152,8 @@ - s_3664: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3728 @@ -72198,6 +79163,8 @@ - s_3666: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3729 @@ -72207,6 +79174,8 @@ - s_3667: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3730 @@ -72216,6 +79185,8 @@ - s_3668: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3731 @@ -72225,6 +79196,8 @@ - s_3693: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3732 @@ -72234,6 +79207,8 @@ - s_3695: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3733 @@ -72243,6 +79218,8 @@ - s_3697: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3734 @@ -72252,6 +79229,8 @@ - s_3699: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3735 @@ -72261,6 +79240,8 @@ - s_3701: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3736 @@ -72270,6 +79251,8 @@ - s_3702: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3737 @@ -72279,6 +79262,8 @@ - s_3703: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3738 @@ -72288,6 +79273,8 @@ - s_3704: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3739 @@ -72297,6 +79284,8 @@ - s_3705: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3740 @@ -72306,6 +79295,8 @@ - s_3706: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3741 @@ -72315,6 +79306,8 @@ - s_3707: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3742 @@ -72324,6 +79317,8 @@ - s_3708: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3743 @@ -72333,6 +79328,8 @@ - s_3686: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3744 @@ -72342,6 +79339,8 @@ - s_3688: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3745 @@ -72351,6 +79350,8 @@ - s_3690: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3746 @@ -72360,6 +79361,8 @@ - s_3692: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3747 @@ -72369,6 +79372,8 @@ - s_3694: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3748 @@ -72378,6 +79383,8 @@ - s_3696: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3749 @@ -72387,6 +79394,8 @@ - s_3698: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3750 @@ -72396,6 +79405,8 @@ - s_3700: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3751 @@ -72405,6 +79416,8 @@ - s_3685: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3752 @@ -72414,6 +79427,8 @@ - s_3687: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3753 @@ -72423,6 +79438,8 @@ - s_3689: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3754 @@ -72432,6 +79449,8 @@ - s_3691: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3755 @@ -72441,6 +79460,8 @@ - s_2962: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3756 @@ -72450,6 +79471,8 @@ - s_2963: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3757 @@ -72459,6 +79482,8 @@ - s_2964: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3758 @@ -72468,6 +79493,8 @@ - s_2965: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3759 @@ -72477,6 +79504,8 @@ - s_3092: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3760 @@ -72486,6 +79515,8 @@ - s_3097: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3761 @@ -72495,6 +79526,8 @@ - s_3099: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3762 @@ -72504,6 +79537,8 @@ - s_3101: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3763 @@ -72513,6 +79548,8 @@ - s_3103: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3764 @@ -72522,6 +79559,8 @@ - s_3105: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3765 @@ -72531,6 +79570,8 @@ - s_3128: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3766 @@ -72540,6 +79581,8 @@ - s_3131: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3767 @@ -72549,6 +79592,8 @@ - s_3133: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3768 @@ -72558,6 +79603,8 @@ - s_3135: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3769 @@ -72567,6 +79614,8 @@ - s_3137: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3770 @@ -72576,6 +79625,8 @@ - s_3139: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3771 @@ -72585,6 +79636,8 @@ - s_3141: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3772 @@ -72594,6 +79647,8 @@ - s_3143: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3773 @@ -72603,6 +79658,8 @@ - s_3181: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3774 @@ -72612,6 +79669,8 @@ - s_3185: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3775 @@ -72621,6 +79680,8 @@ - s_3187: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3776 @@ -72630,6 +79691,8 @@ - s_3189: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3777 @@ -72639,6 +79702,8 @@ - s_3191: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3778 @@ -72648,6 +79713,8 @@ - s_3193: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3779 @@ -72657,6 +79724,8 @@ - s_3195: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3780 @@ -72666,6 +79735,8 @@ - s_3197: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3781 @@ -72675,6 +79746,8 @@ - s_3296: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3782 @@ -72684,6 +79757,8 @@ - s_3298: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3783 @@ -72693,6 +79768,8 @@ - s_3300: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3784 @@ -72702,6 +79779,8 @@ - s_3302: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3785 @@ -72711,6 +79790,8 @@ - s_3304: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3786 @@ -72720,6 +79801,8 @@ - s_3305: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3787 @@ -72729,6 +79812,8 @@ - s_3306: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3788 @@ -72738,6 +79823,8 @@ - s_3307: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3789 @@ -72747,6 +79834,8 @@ - s_2996: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3790 @@ -72756,6 +79845,8 @@ - s_3000: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3791 @@ -72765,6 +79856,8 @@ - s_3004: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3792 @@ -72774,6 +79867,8 @@ - s_3008: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3793 @@ -72783,6 +79878,8 @@ - s_2998: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3794 @@ -72792,6 +79889,8 @@ - s_3002: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3795 @@ -72801,6 +79900,8 @@ - s_3006: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3796 @@ -72810,6 +79911,8 @@ - s_3010: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3797 @@ -72819,6 +79922,8 @@ - s_2993: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3798 @@ -72828,6 +79933,8 @@ - s_2999: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3799 @@ -72837,6 +79944,8 @@ - s_3003: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3800 @@ -72846,6 +79955,8 @@ - s_3007: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3801 @@ -72855,6 +79966,8 @@ - s_2997: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3802 @@ -72864,6 +79977,8 @@ - s_3001: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3803 @@ -72873,6 +79988,8 @@ - s_3005: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3804 @@ -72882,6 +79999,8 @@ - s_3009: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3805 @@ -72891,6 +80010,8 @@ - s_3358: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3806 @@ -72900,6 +80021,8 @@ - s_3362: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3807 @@ -72909,6 +80032,8 @@ - s_3364: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3808 @@ -72918,6 +80043,8 @@ - s_3366: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3809 @@ -72927,6 +80054,8 @@ - s_3368: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3810 @@ -72936,6 +80065,8 @@ - s_3370: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3811 @@ -72945,6 +80076,8 @@ - s_3372: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3812 @@ -72954,6 +80087,8 @@ - s_3374: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3813 @@ -72963,6 +80098,8 @@ - s_3145: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3814 @@ -72972,6 +80109,8 @@ - s_3149: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3815 @@ -72981,6 +80120,8 @@ - s_3151: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3816 @@ -72990,6 +80131,8 @@ - s_3153: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3817 @@ -72999,6 +80142,8 @@ - s_3155: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3818 @@ -73008,6 +80153,8 @@ - s_3157: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3819 @@ -73017,6 +80164,8 @@ - s_3159: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3820 @@ -73026,6 +80175,8 @@ - s_3161: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3821 @@ -73035,6 +80186,8 @@ - s_3181: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3822 @@ -73044,6 +80197,8 @@ - s_3185: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3823 @@ -73053,6 +80208,8 @@ - s_3187: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3824 @@ -73062,6 +80219,8 @@ - s_3189: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3825 @@ -73071,6 +80230,8 @@ - s_3191: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3826 @@ -73080,6 +80241,8 @@ - s_3193: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3827 @@ -73089,6 +80252,8 @@ - s_3195: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3828 @@ -73098,6 +80263,8 @@ - s_3197: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3829 @@ -73107,6 +80274,8 @@ - s_2975: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3830 @@ -73116,6 +80285,8 @@ - s_2981: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3831 @@ -73125,6 +80296,8 @@ - s_2985: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3832 @@ -73134,6 +80307,8 @@ - s_2989: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3833 @@ -73143,6 +80318,8 @@ - s_2979: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3834 @@ -73152,6 +80329,8 @@ - s_2983: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3835 @@ -73161,6 +80340,8 @@ - s_2987: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3836 @@ -73170,6 +80351,8 @@ - s_2991: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3837 @@ -73179,6 +80362,8 @@ - s_3340: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3838 @@ -73188,6 +80373,8 @@ - s_3344: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3839 @@ -73197,6 +80384,8 @@ - s_3346: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3840 @@ -73206,6 +80395,8 @@ - s_3348: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3841 @@ -73215,6 +80406,8 @@ - s_3350: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3842 @@ -73224,6 +80417,8 @@ - s_3352: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3843 @@ -73233,6 +80428,8 @@ - s_3354: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3844 @@ -73242,6 +80439,8 @@ - s_3356: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3845 @@ -73251,6 +80450,8 @@ - s_3163: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3846 @@ -73260,6 +80461,8 @@ - s_3167: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3847 @@ -73269,6 +80472,8 @@ - s_3169: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3848 @@ -73278,6 +80483,8 @@ - s_3171: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3849 @@ -73287,6 +80494,8 @@ - s_3173: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3850 @@ -73296,6 +80505,8 @@ - s_3175: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3851 @@ -73305,6 +80516,8 @@ - s_3177: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3852 @@ -73314,6 +80527,8 @@ - s_3179: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3853 @@ -73323,6 +80538,8 @@ - s_3181: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3854 @@ -73332,6 +80549,8 @@ - s_3185: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3855 @@ -73341,6 +80560,8 @@ - s_3187: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3856 @@ -73350,6 +80571,8 @@ - s_3189: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3857 @@ -73359,6 +80582,8 @@ - s_3191: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3858 @@ -73368,6 +80593,8 @@ - s_3193: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3859 @@ -73377,6 +80604,8 @@ - s_3195: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3860 @@ -73386,6 +80615,8 @@ - s_3197: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3861 @@ -73395,6 +80626,8 @@ - s_3560: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3862 @@ -73404,6 +80637,8 @@ - s_3561: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3863 @@ -73413,6 +80648,8 @@ - s_3562: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3864 @@ -73422,6 +80659,8 @@ - s_3563: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3865 @@ -73431,6 +80670,8 @@ - s_3564: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3866 @@ -73440,6 +80681,8 @@ - s_3565: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3867 @@ -73449,6 +80692,8 @@ - s_3566: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3868 @@ -73458,6 +80703,8 @@ - s_3567: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3869 @@ -73467,6 +80714,8 @@ - s_3323: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3870 @@ -73476,6 +80725,8 @@ - s_3326: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3871 @@ -73485,6 +80736,8 @@ - s_3328: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3872 @@ -73494,6 +80747,8 @@ - s_3330: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3873 @@ -73503,6 +80758,8 @@ - s_3332: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3874 @@ -73512,6 +80769,8 @@ - s_3334: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3875 @@ -73521,6 +80780,8 @@ - s_3336: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3876 @@ -73530,6 +80791,8 @@ - s_3338: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3877 @@ -73539,6 +80802,8 @@ - s_3448: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3878 @@ -73548,6 +80813,8 @@ - s_3452: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3879 @@ -73557,6 +80824,8 @@ - s_3454: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3880 @@ -73566,6 +80835,8 @@ - s_3456: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3881 @@ -73575,6 +80846,8 @@ - s_3458: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3882 @@ -73584,6 +80857,8 @@ - s_3460: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3883 @@ -73593,6 +80868,8 @@ - s_3461: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3884 @@ -73602,6 +80879,8 @@ - s_3462: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3885 @@ -73611,6 +80890,8 @@ - s_3465: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3886 @@ -73620,6 +80901,8 @@ - s_3467: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3887 @@ -73629,6 +80912,8 @@ - s_3469: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3888 @@ -73638,6 +80923,8 @@ - s_3471: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3889 @@ -73647,6 +80934,8 @@ - s_3473: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3890 @@ -73656,6 +80945,8 @@ - s_3474: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3891 @@ -73665,6 +80956,8 @@ - s_3475: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3892 @@ -73674,6 +80967,8 @@ - s_3476: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3893 @@ -73683,6 +80978,8 @@ - s_3478: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3894 @@ -73692,6 +80989,8 @@ - s_3480: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3895 @@ -73701,6 +81000,8 @@ - s_3482: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3896 @@ -73710,6 +81011,8 @@ - s_3484: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3897 @@ -73719,6 +81022,8 @@ - s_3486: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3898 @@ -73728,6 +81033,8 @@ - s_3487: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3899 @@ -73737,6 +81044,8 @@ - s_3488: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3900 @@ -73746,6 +81055,8 @@ - s_3489: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3901 @@ -73755,6 +81066,8 @@ - s_2869: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3902 @@ -73764,6 +81077,8 @@ - s_2870: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3903 @@ -73773,6 +81088,8 @@ - s_3527: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3904 @@ -73782,6 +81099,8 @@ - s_3528: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3905 @@ -73791,6 +81110,8 @@ - s_3529: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3906 @@ -73800,6 +81121,8 @@ - s_3530: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3907 @@ -73809,6 +81132,8 @@ - s_3531: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3908 @@ -73818,6 +81143,8 @@ - s_3532: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3909 @@ -73827,6 +81154,8 @@ - s_3533: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3910 @@ -73836,6 +81165,8 @@ - s_3534: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3911 @@ -73845,6 +81176,8 @@ - s_3584: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3912 @@ -73854,6 +81187,8 @@ - s_3585: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3913 @@ -73863,6 +81198,8 @@ - s_3586: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3914 @@ -73872,6 +81209,8 @@ - s_3587: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3915 @@ -73881,6 +81220,8 @@ - s_3588: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3916 @@ -73890,6 +81231,8 @@ - s_3589: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3917 @@ -73899,6 +81242,8 @@ - s_3590: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3918 @@ -73908,6 +81253,8 @@ - s_3591: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3919 @@ -73917,6 +81264,8 @@ - s_3608: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3920 @@ -73926,6 +81275,8 @@ - s_3609: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3921 @@ -73935,6 +81286,8 @@ - s_3610: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3922 @@ -73944,6 +81297,8 @@ - s_3611: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3923 @@ -73953,6 +81308,8 @@ - s_3612: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3924 @@ -73962,6 +81319,8 @@ - s_3613: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3925 @@ -73971,6 +81330,8 @@ - s_3614: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3926 @@ -73980,6 +81341,8 @@ - s_3615: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3927 @@ -73989,6 +81352,8 @@ - s_3669: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3928 @@ -73998,6 +81363,8 @@ - s_3670: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3929 @@ -74007,6 +81374,8 @@ - s_3376: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3930 @@ -74016,6 +81385,8 @@ - s_3378: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3931 @@ -74025,6 +81396,8 @@ - s_3380: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3932 @@ -74034,6 +81407,8 @@ - s_3382: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3933 @@ -74043,6 +81418,8 @@ - s_3384: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3934 @@ -74052,6 +81429,8 @@ - s_3386: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3935 @@ -74061,6 +81440,8 @@ - s_3388: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3936 @@ -74070,6 +81451,8 @@ - s_3390: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3937 @@ -74079,6 +81462,8 @@ - s_2869: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3938 @@ -74088,6 +81473,8 @@ - s_2870: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3939 @@ -74097,6 +81484,8 @@ - s_3441: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3940 @@ -74106,6 +81495,8 @@ - s_2966: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3941 @@ -74115,6 +81506,8 @@ - s_3568: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3942 @@ -74124,6 +81517,8 @@ - s_3569: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3943 @@ -74133,6 +81528,8 @@ - s_3570: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3944 @@ -74142,6 +81539,8 @@ - s_3571: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3945 @@ -74151,6 +81550,8 @@ - s_3572: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3946 @@ -74160,6 +81561,8 @@ - s_3573: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3947 @@ -74169,6 +81572,8 @@ - s_3574: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3948 @@ -74178,6 +81583,8 @@ - s_3575: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3949 @@ -74187,6 +81594,8 @@ - s_3592: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3950 @@ -74196,6 +81605,8 @@ - s_3593: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3951 @@ -74205,6 +81616,8 @@ - s_3594: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3952 @@ -74214,6 +81627,8 @@ - s_3595: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3953 @@ -74223,6 +81638,8 @@ - s_3596: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3954 @@ -74232,6 +81649,8 @@ - s_3597: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3955 @@ -74241,6 +81660,8 @@ - s_3598: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3956 @@ -74250,6 +81671,8 @@ - s_3599: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3957 @@ -74259,6 +81682,8 @@ - s_3094: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3958 @@ -74268,6 +81693,8 @@ - s_3218: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3959 @@ -74277,6 +81704,8 @@ - s_3219: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3960 @@ -74286,6 +81715,8 @@ - s_3093: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3961 @@ -74295,6 +81726,8 @@ - s_3228: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3962 @@ -74304,6 +81737,8 @@ - s_3095: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_3963 @@ -74315,6 +81750,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3964 @@ -74325,6 +81762,8 @@ - s_3741: 0.50883 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3965 @@ -74336,6 +81775,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3966 @@ -74347,6 +81788,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3967 @@ -74358,6 +81801,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3968 @@ -74369,6 +81814,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3969 @@ -74380,6 +81827,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3970 @@ -74390,6 +81839,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3971 @@ -74400,6 +81851,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3972 @@ -74410,6 +81863,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3973 @@ -74419,6 +81874,8 @@ - s_3709: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_3975 @@ -74429,6 +81886,8 @@ - s_3740: 0.25643 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3976 @@ -74439,6 +81898,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3977 @@ -74449,6 +81910,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3978 @@ -74459,6 +81922,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3979 @@ -74470,6 +81935,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3980 @@ -74480,6 +81947,8 @@ - s_3741: 0.50883 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3981 @@ -74491,6 +81960,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3982 @@ -74502,6 +81973,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3983 @@ -74513,6 +81986,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3984 @@ -74524,6 +81999,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3985 @@ -74535,6 +82012,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3986 @@ -74545,6 +82024,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3987 @@ -74554,6 +82035,8 @@ - s_3710: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_3988 @@ -74565,6 +82048,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3989 @@ -74575,6 +82060,8 @@ - s_3741: 0.50883 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3990 @@ -74586,6 +82073,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3991 @@ -74597,6 +82086,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3992 @@ -74608,6 +82099,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3993 @@ -74619,6 +82112,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3994 @@ -74630,6 +82125,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3995 @@ -74640,6 +82137,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3996 @@ -74649,6 +82148,8 @@ - s_3711: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_3997 @@ -74660,6 +82161,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3998 @@ -74670,6 +82173,8 @@ - s_3741: 0.50883 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_3999 @@ -74681,6 +82186,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4000 @@ -74692,6 +82199,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4001 @@ -74703,6 +82212,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4002 @@ -74714,6 +82225,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4003 @@ -74725,6 +82238,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4004 @@ -74735,6 +82250,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4005 @@ -74744,6 +82261,8 @@ - s_3712: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4006 @@ -74755,6 +82274,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4007 @@ -74766,6 +82287,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4008 @@ -74777,6 +82300,8 @@ - s_3741: 0.50883 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4009 @@ -74789,6 +82314,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4010 @@ -74801,6 +82328,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4011 @@ -74813,6 +82342,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4012 @@ -74825,6 +82356,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4013 @@ -74836,6 +82369,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4014 @@ -74847,6 +82382,8 @@ - s_3741: 0.50883 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4015 @@ -74859,6 +82396,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4016 @@ -74869,6 +82408,8 @@ - s_3741: 0.76324 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4017 @@ -74880,6 +82421,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4018 @@ -74891,6 +82434,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4019 @@ -74903,6 +82448,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4020 @@ -74914,6 +82461,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4021 @@ -74925,6 +82474,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4022 @@ -74937,6 +82488,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4023 @@ -74949,6 +82502,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4024 @@ -74960,6 +82515,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4025 @@ -74972,6 +82529,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4026 @@ -74983,6 +82542,8 @@ - s_3742: 0.56897 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4027 @@ -74994,6 +82555,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4028 @@ -75006,6 +82569,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4029 @@ -75017,6 +82582,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4030 @@ -75029,6 +82596,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4031 @@ -75040,6 +82609,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4032 @@ -75051,6 +82622,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4033 @@ -75062,6 +82635,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4034 @@ -75074,6 +82649,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4035 @@ -75085,6 +82662,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4036 @@ -75096,6 +82675,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4037 @@ -75106,6 +82687,8 @@ - s_3743: 0.8474 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4038 @@ -75115,6 +82698,8 @@ - s_3713: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4039 @@ -75131,6 +82716,7 @@ - annotation: !!omap - ec-code: 3.1.2.1 - pmid: 19298859 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_4040 @@ -75140,6 +82726,8 @@ - s_3714: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 0 - !!omap - id: r_4041 @@ -75161,6 +82749,8 @@ - s_3720: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000629 - confidence_score: 1 - !!omap - id: r_4042 @@ -75179,6 +82769,7 @@ - annotation: !!omap - ec-code: 5.3.1.16 - pmid: 4967422 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_4043 @@ -75187,6 +82778,8 @@ - s_3715: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4044 - name: melibiose exchange @@ -75194,6 +82787,8 @@ - s_3716: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4045 - name: uridine hydrolase @@ -75211,6 +82806,7 @@ - annotation: !!omap - ec-code: 3.2.2.3 - pmid: 23670538 + - sbo: SBO:0000176 - confidence_score: 3 - !!omap - id: r_4046 @@ -75223,6 +82819,8 @@ - s_1322: 1 - lower_bound: 0.7 - upper_bound: 0.7 + - annotation: !!omap + - sbo: SBO:0000630 - confidence_score: 0 - !!omap - id: r_4047 @@ -75271,6 +82869,8 @@ - s_3717: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4048 @@ -75284,6 +82884,8 @@ - s_3718: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4049 @@ -75296,6 +82898,8 @@ - s_3719: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4050 @@ -75308,6 +82912,8 @@ - s_3720: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4051 @@ -75317,6 +82923,8 @@ - s_3722: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4052 @@ -75326,6 +82934,8 @@ - s_3723: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4053 @@ -75335,6 +82945,8 @@ - s_3724: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4054 @@ -75344,6 +82956,8 @@ - s_3725: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4055 @@ -75353,6 +82967,8 @@ - s_3727: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4056 @@ -75362,6 +82978,8 @@ - s_3729: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4057 @@ -75371,6 +82989,8 @@ - s_3731: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4058 @@ -75380,6 +83000,8 @@ - s_3733: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4059 @@ -75389,6 +83011,8 @@ - s_3735: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4060 @@ -75398,6 +83022,8 @@ - s_3737: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4061 @@ -75407,6 +83033,8 @@ - s_3739: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4062 @@ -75415,6 +83043,8 @@ - s_3746: -1 - lower_bound: 0 - upper_bound: 0 + - annotation: !!omap + - sbo: SBO:0000632 - !!omap - id: r_4063 - name: lipid backbone pseudoreaction @@ -75430,6 +83060,8 @@ - s_3746: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4064 @@ -75438,6 +83070,8 @@ - s_3747: -1 - lower_bound: 0 - upper_bound: 0 + - annotation: !!omap + - sbo: SBO:0000632 - !!omap - id: r_4065 - name: lipid chain pseudoreaction @@ -75449,6 +83083,8 @@ - s_3747: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4066 @@ -75460,6 +83096,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4067 @@ -75471,6 +83109,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4068 @@ -75482,6 +83122,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4069 @@ -75493,6 +83135,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4070 @@ -75504,6 +83148,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4071 @@ -75515,6 +83161,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4072 @@ -75526,6 +83174,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4073 @@ -75537,6 +83187,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4074 @@ -75548,6 +83200,8 @@ - s_3744: 0.36864 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4075 @@ -75559,6 +83213,8 @@ - s_3745: 0.3967 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4076 @@ -75569,6 +83225,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4077 @@ -75579,6 +83237,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4078 @@ -75589,6 +83249,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4079 @@ -75599,6 +83261,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4080 @@ -75610,6 +83274,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4081 @@ -75621,6 +83287,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4082 @@ -75631,6 +83299,8 @@ - s_3741: 0.50883 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4083 @@ -75642,6 +83312,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4084 @@ -75653,6 +83325,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4085 @@ -75664,6 +83338,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4086 @@ -75675,6 +83351,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4087 @@ -75685,6 +83363,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4088 @@ -75696,6 +83376,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4089 @@ -75707,6 +83389,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4090 @@ -75717,6 +83401,8 @@ - s_3741: 0.50883 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4091 @@ -75728,6 +83414,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4092 @@ -75739,6 +83427,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4093 @@ -75750,6 +83440,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4094 @@ -75761,6 +83453,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4095 @@ -75771,6 +83465,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4096 @@ -75781,6 +83477,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4097 @@ -75791,6 +83489,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4098 @@ -75802,6 +83502,8 @@ - s_3741: 0.25441 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4099 @@ -75812,6 +83514,8 @@ - s_3741: 0.50883 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4100 @@ -75823,6 +83527,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4101 @@ -75834,6 +83540,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4102 @@ -75845,6 +83553,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4103 @@ -75856,6 +83566,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4104 @@ -75867,6 +83579,8 @@ - s_3741: 0.50883 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4105 @@ -75878,6 +83592,8 @@ - s_3741: 0.76324 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4106 @@ -75890,6 +83606,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4107 @@ -75902,6 +83620,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4108 @@ -75914,6 +83634,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4109 @@ -75926,6 +83648,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4110 @@ -75937,6 +83661,8 @@ - s_3741: 0.76324 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4111 @@ -75947,6 +83673,8 @@ - s_3741: 1.0177 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4112 @@ -75958,6 +83686,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4113 @@ -75969,6 +83699,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4114 @@ -75981,6 +83713,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4115 @@ -75992,6 +83726,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4116 @@ -76004,6 +83740,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4117 @@ -76015,6 +83753,8 @@ - s_3742: 0.28448 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4118 @@ -76026,6 +83766,8 @@ - s_3742: 0.56897 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4119 @@ -76038,6 +83780,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4120 @@ -76051,6 +83795,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4121 @@ -76063,6 +83809,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4122 @@ -76075,6 +83823,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4123 @@ -76086,6 +83836,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4124 @@ -76098,6 +83850,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4125 @@ -76109,6 +83863,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4126 @@ -76121,6 +83877,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4127 @@ -76132,6 +83890,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4128 @@ -76144,6 +83904,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4129 @@ -76156,6 +83918,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4130 @@ -76169,6 +83933,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4131 @@ -76181,6 +83947,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4132 @@ -76192,6 +83960,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4133 @@ -76204,6 +83974,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4134 @@ -76216,6 +83988,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4135 @@ -76227,6 +84001,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4136 @@ -76239,6 +84015,8 @@ - s_3743: 0.28247 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4137 @@ -76250,6 +84028,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4138 @@ -76262,6 +84042,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4139 @@ -76273,6 +84055,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4140 @@ -76285,6 +84069,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4141 @@ -76296,6 +84082,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4142 @@ -76308,6 +84096,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4143 @@ -76319,6 +84109,8 @@ - s_3743: 0.8474 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4144 @@ -76330,6 +84122,8 @@ - s_3743: 0.8474 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4145 @@ -76341,6 +84135,8 @@ - s_3743: 0.8474 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4146 @@ -76353,6 +84149,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4147 @@ -76364,6 +84162,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4148 @@ -76376,6 +84176,8 @@ - s_3743: 0.56493 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4149 @@ -76387,6 +84189,8 @@ - s_3743: 0.8474 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4150 @@ -76398,6 +84202,8 @@ - s_3743: 0.8474 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4151 @@ -76409,6 +84215,8 @@ - s_3743: 0.8474 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000395 - confidence_score: 1 - !!omap - id: r_4152 @@ -76425,6 +84233,7 @@ - 4.4.1.17 - 4.4.1.- - kegg.reaction: R02480 + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_4153 @@ -76441,6 +84250,7 @@ - annotation: !!omap - ec-code: 1.1.1.303 - kegg.reaction: R02855 + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_4154 @@ -76457,6 +84267,7 @@ - annotation: !!omap - ec-code: 1.1.1.303 - kegg.reaction: R02855 + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_4155 @@ -76476,6 +84287,7 @@ - gene_reaction_rule: YBL080C - annotation: !!omap - ec-code: 6.3.5.- + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_4156 @@ -76490,6 +84302,7 @@ - gene_reaction_rule: YBL091C or YLR244C - annotation: !!omap - ec-code: 3.4.11.18 + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_4157 @@ -76506,6 +84319,7 @@ - ec-code: - 3.1.3.84 - 3.2.2.- + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_4158 @@ -76522,6 +84336,7 @@ - annotation: !!omap - ec-code: 1.6.5.5 - kegg.reaction: R02364 + - sbo: SBO:0000176 - confidence_score: 0 - !!omap - id: r_4159 @@ -76538,6 +84353,7 @@ - annotation: !!omap - ec-code: 2.4.1.141 - kegg.reaction: R05970 + - sbo: SBO:0000176 - 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metanetx.reaction: MNXR137133 + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4475 @@ -80794,6 +89133,8 @@ - s_4173: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4476 @@ -80803,6 +89144,8 @@ - s_4173: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4477 @@ -80814,6 +89157,9 @@ - s_4175: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - metanetx.reaction: MNXR137094 + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4478 @@ -80823,6 +89169,9 @@ - s_4176: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - metanetx.reaction: MNXR101483 + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4479 @@ -80834,6 +89183,8 @@ - s_4055: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4480 @@ -80845,6 +89196,9 @@ - s_4074: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - metanetx.reaction: MNXR137130 + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4481 @@ -80856,6 +89210,8 @@ - s_1467: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4482 @@ -80867,6 +89223,9 @@ - s_3759: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - metanetx.reaction: MNXR95704 + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4483 @@ -80878,6 +89237,9 @@ - s_3839: 1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - metanetx.reaction: MNXR100368 + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4484 @@ -80895,6 +89257,8 @@ - 2.5.1.- - 2.5.1.48 - kegg.reaction: R01288 + - metanetx.reaction: MNXR104382 + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4485 @@ -80909,6 +89273,8 @@ - annotation: !!omap - ec-code: 1.13.11.27 - kegg.reaction: R02521 + - metanetx.reaction: MNXR94843 + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4486 @@ -80923,6 +89289,8 @@ - annotation: !!omap - ec-code: 1.13.11.5 - kegg.reaction: R02519 + - metanetx.reaction: MNXR100628 + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4487 @@ -80935,6 +89303,8 @@ - annotation: !!omap - ec-code: 5.2.1.2 - kegg.reaction: R03181 + - metanetx.reaction: MNXR101325 + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4488 @@ -80950,6 +89320,8 @@ - annotation: !!omap - ec-code: 3.7.1.2 - kegg.reaction: R01364 + - metanetx.reaction: MNXR99706 + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4489 @@ -80965,6 +89337,8 @@ - annotation: !!omap - ec-code: 1.1.1.12 - kegg.reaction: R01903 + - metanetx.reaction: MNXR95187 + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4490 @@ -80980,6 +89354,8 @@ - annotation: !!omap - ec-code: 1.1.1.10 - kegg.reaction: R01904 + - metanetx.reaction: MNXR105265 + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4491 @@ -80992,6 +89368,8 @@ - s_4181: 1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4492 @@ -81007,6 +89385,8 @@ - annotation: !!omap - ec-code: 1.1.1.11 - kegg.reaction: R05604 + - metanetx.reaction: MNXR95188 + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4493 @@ -81016,6 +89396,9 @@ - s_4133: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - metanetx.reaction: MNXR95208 + - sbo: SBO:0000655 - confidence_score: 1 - !!omap - id: r_4494 @@ -81024,6 +89407,9 @@ - s_4124: -1 - lower_bound: -1000 - upper_bound: 1000 + - annotation: !!omap + - metanetx.reaction: MNXR98748 + - sbo: SBO:0000627 - confidence_score: 1 - !!omap - id: r_4495 @@ -81037,6 +89423,8 @@ - upper_bound: 1000 - annotation: !!omap - ec-code: 3.1.3.- + - metanetx.reaction: MNXR118733 + - sbo: SBO:0000176 - confidence_score: 1 - !!omap - id: r_4496 @@ -81045,6 +89433,8 @@ - s_4170: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4497 - name: 3-oxalomalate(3-) exchange @@ -81052,6 +89442,8 @@ - s_4137: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4498 - name: 6-O-alpha-D-glucopyranosyl-D-fructofuranose exchange @@ -81059,6 +89451,8 @@ - s_4109: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4499 - name: 5-dehydro-D-gluconate exchange @@ -81066,6 +89460,8 @@ - s_4118: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4500 - name: D-tagatose exchange @@ -81073,6 +89469,8 @@ - s_4130: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4501 - name: turanose exchange @@ -81080,6 +89478,8 @@ - s_4131: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4502 - name: D-glucose 6-phosphate exchange @@ -81087,6 +89487,8 @@ - s_4150: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4503 - name: alpha-maltotriose exchange @@ -81094,6 +89496,8 @@ - s_4140: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4504 - name: D-glucose 1-phosphate exchange @@ -81101,6 +89505,8 @@ - s_4145: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4505 - name: methyl alpha-D-glucopyranoside exchange @@ -81108,6 +89514,8 @@ - s_4125: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4506 - name: D-Glucosamine exchange @@ -81115,6 +89523,8 @@ - s_4164: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4507 - name: glycerone exchange @@ -81122,6 +89532,8 @@ - s_4167: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4508 - name: Ala-Gln exchange @@ -81129,6 +89541,8 @@ - s_4034: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4509 - name: Ala-Leu exchange @@ -81136,6 +89550,8 @@ - s_4168: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4510 - name: Gly-Gln exchange @@ -81143,6 +89559,8 @@ - s_4056: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4511 - name: Ala-His exchange @@ -81150,6 +89568,8 @@ - s_4050: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4512 - name: Gly-Asn exchange @@ -81157,6 +89577,8 @@ - s_4053: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4513 - name: Ala-Glu exchange @@ -81164,6 +89586,8 @@ - s_4037: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4514 - name: Gly-Met exchange @@ -81171,6 +89595,8 @@ - s_4085: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4515 - name: Ala-Asp exchange @@ -81178,6 +89604,8 @@ - s_4119: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4516 - name: Gly-Glu exchange @@ -81185,6 +89613,8 @@ - s_4059: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4517 - name: Ala-Thr exchange @@ -81192,6 +89622,8 @@ - s_4040: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4518 - name: Met-Ala exchange @@ -81199,6 +89631,8 @@ - s_4143: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4519 - name: L-citrulline exchange @@ -81206,6 +89640,8 @@ - s_4166: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4520 - name: 2-aminobutanoate exchange @@ -81213,6 +89649,8 @@ - s_4080: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4521 - name: choline phosphate exchange @@ -81220,6 +89658,8 @@ - s_4158: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4522 - name: glycerol 1-phosphate exchange @@ -81227,6 +89667,8 @@ - s_4049: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4523 - name: 2-phospho-D-glyceric acid exchange @@ -81234,6 +89676,8 @@ - s_4141: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4524 - name: GMP exchange @@ -81241,6 +89685,8 @@ - s_4148: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4525 - name: 3-phospho-serine exchange @@ -81248,6 +89694,8 @@ - s_4147: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4526 - name: O-phosphonatooxy-D-serine(2-) exchange @@ -81255,6 +89703,8 @@ - s_4078: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4527 - name: diphosphate exchange @@ -81262,6 +89712,8 @@ - s_4157: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4528 - name: triphosphate exchange @@ -81269,6 +89721,8 @@ - s_4099: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4529 - name: phosphoenolpyruvate exchange @@ -81276,6 +89730,8 @@ - s_4152: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4530 - name: N(omega)-phospho-L-arginine exchange @@ -81283,6 +89739,8 @@ - s_4093: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4531 - name: carbamoyl phosphate exchange @@ -81290,6 +89748,8 @@ - s_4146: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4532 - name: O-phosphoethanolamine exchange @@ -81297,6 +89757,8 @@ - s_4154: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4533 - name: cysteamine S-phosphate exchange @@ -81304,6 +89766,8 @@ - s_4075: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4534 - name: guanosine 2'-monophosphate exchange @@ -81311,6 +89775,8 @@ - s_4067: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4535 - name: glycerol 2-phosphate(2-) exchange @@ -81318,6 +89784,8 @@ - s_4063: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4536 - name: 3'-GMP exchange @@ -81325,6 +89793,8 @@ - s_4069: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4537 - name: 2-phosphoglycolate exchange @@ -81332,6 +89802,8 @@ - s_4070: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4538 - name: 6-phospho-D-gluconate exchange @@ -81339,6 +89811,8 @@ - s_4155: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4539 - name: D-mannose 6-phosphate exchange @@ -81346,6 +89820,8 @@ - s_4153: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4540 - name: 2',3'-cyclic GMP exchange @@ -81353,6 +89829,8 @@ - s_4095: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4541 - name: O(4)-phospho-L-tyrosine exchange @@ -81360,6 +89838,8 @@ - s_4097: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4542 - name: O-phospho-L-threonine exchange @@ -81367,6 +89847,8 @@ - s_4065: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4543 - name: 3-phosphonato-D-glycerate(3-) exchange @@ -81374,6 +89856,8 @@ - s_4142: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4544 - name: adenosine 2'-phosphate exchange @@ -81381,6 +89865,8 @@ - s_4162: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4545 - name: 3'-AMP exchange @@ -81388,6 +89874,8 @@ - s_4107: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4546 - name: 2',3'-cyclic AMP exchange @@ -81395,6 +89883,8 @@ - s_4161: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4547 - name: D-mannose 1-phosphate exchange @@ -81402,6 +89892,8 @@ - s_4156: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4548 - name: AMP exchange @@ -81409,6 +89901,8 @@ - s_4160: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4549 - name: N(alpha)-acetyl-L-methionine exchange @@ -81416,6 +89910,8 @@ - s_4135: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4550 - name: L-Methionine S-oxide exchange @@ -81423,6 +89919,8 @@ - s_4176: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4551 - name: 3-sulfino-L-alanine exchange @@ -81430,6 +89928,8 @@ - s_4105: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4552 - name: N-acetyl-L-cysteine exchange @@ -81437,6 +89937,8 @@ - s_4111: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4553 - name: L-cysteate exchange @@ -81444,6 +89946,8 @@ - s_4139: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4554 - name: 2-hydroxyethane-1-sulfonate exchange @@ -81451,6 +89955,8 @@ - s_4116: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4555 - name: acetoacetate exchange @@ -81458,6 +89964,8 @@ - s_4133: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4556 - name: N-acetyl-L-glutamate exchange @@ -81465,6 +89973,8 @@ - s_4172: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4557 - name: UMP exchange @@ -81472,6 +89982,8 @@ - s_4151: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4558 - name: CMP exchange @@ -81479,6 +89991,8 @@ - s_4163: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4559 - name: thymidine 5'-monophosphate exchange @@ -81486,6 +90000,8 @@ - s_4047: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4560 - name: thymidine 3'-monophosphate exchange @@ -81493,6 +90009,8 @@ - s_4045: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4561 - name: cytidine 2'-phosphate exchange @@ -81500,6 +90018,8 @@ - s_4101: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4562 - name: uridine 2'-phosphate exchange @@ -81507,6 +90027,8 @@ - s_4082: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4563 - name: 3'-UMP exchange @@ -81514,6 +90036,8 @@ - s_4084: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4564 - name: 2',3'-cyclic CMP exchange @@ -81521,6 +90045,8 @@ - s_4127: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - !!omap - id: r_4565 - name: 2',3'-cyclic UMP exchange @@ -81528,6 +90054,8 @@ - s_4103: -1 - lower_bound: 0 - upper_bound: 1000 + - annotation: !!omap + - sbo: SBO:0000627 - genes: - !!omap - id: Q0045 From 3a9b763c4c312daedb52d983a971d3d0c5c3cff5 Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Fri, 31 Aug 2018 10:36:06 +0200 Subject: [PATCH 24/27] fix: saveYeastModel * removing spaces in rxnECNumbers is no longer necessary * model.grRules is now deleted to avoid conflicts * added doc --- ComplementaryScripts/saveYeastModel.m | 14 ++++++++++---- 1 file changed, 10 insertions(+), 4 deletions(-) diff --git a/ComplementaryScripts/saveYeastModel.m b/ComplementaryScripts/saveYeastModel.m index 6c7f121c..e3005bd5 100644 --- a/ComplementaryScripts/saveYeastModel.m +++ b/ComplementaryScripts/saveYeastModel.m @@ -3,7 +3,11 @@ % Saves model as a .xml, .txt and .yml file. Also updates complementary % files (boundaryMets.txt, README.md and dependencies.txt). % -% Benjamín J. Sánchez +% model model structure to save (note: must be in COBRA format) +% upDATE logical =true if updating the date in the README file is needed +% (opt, default true) +% +% Benjamin J. Sanchez %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% function saveYeastModel(model,upDATE) @@ -12,14 +16,16 @@ function saveYeastModel(model,upDATE) upDATE = true; end -%Remove any space in rxnECNumbers: -model.rxnECNumbers = strrep(model.rxnECNumbers,' ',''); - %Get and change to the script folder, as all folders are relative to this %folder scriptFolder = fileparts(which(mfilename)); currentDir = cd(scriptFolder); +%Delete model.grRules (redundant and possibly conflicting with model.rules): +if isfield(model,'grRules') + model = rmfield(model,'grRules'); +end + %Update SBO terms in model: cd missingFields model = addSBOterms(model); From 1a9c75bfe8b7706a207e67c0ab8bff9273d6b642 Mon Sep 17 00:00:00 2001 From: FEIRANL Date: Wed, 5 Sep 2018 17:24:06 +0200 Subject: [PATCH 25/27] fix-SaveYeastModel When save the model, we set the media to be minimal media --- .../modelCuration/minimal_Y6.m | 20 +++++++++++++++---- ComplementaryScripts/saveYeastModel.m | 2 ++ 2 files changed, 18 insertions(+), 4 deletions(-) diff --git a/ComplementaryScripts/modelCuration/minimal_Y6.m b/ComplementaryScripts/modelCuration/minimal_Y6.m index 75150349..a7581523 100755 --- a/ComplementaryScripts/modelCuration/minimal_Y6.m +++ b/ComplementaryScripts/modelCuration/minimal_Y6.m @@ -1,10 +1,14 @@ function model = minimal_Y6(model) % change Y6 model media to minimal - ammonium, glucose, oxygen, % phosphate, sulphate +% Bicarbonate production is blocked to get rid of conflict due to bicarbonate and carbon dioxide +% are regarded as equivalent % the function is from:https://doi.org/10.1371/journal.pcbi.1004530 % start with a clean slate: set all exchange reactions to upper bound = 1000 % and lower bound = 0 (ie, unconstrained excretion, no uptake) + +%Feiran Li 2018.09.25 exchangeRxns = findExcRxns(model); model.lb(exchangeRxns) = 0; model.ub(exchangeRxns) = 1000; @@ -13,18 +17,26 @@ 'r_2005'; ... % 'phosphate exchange'; 'r_2060'; ... % 'sulphate exchange'; 'r_1861'; ... % iron for test of expanded biomass def; - 'r_1832'}; % hydrogen exchange; - + 'r_1832'; ... % hydrogen exchange; + 'r_2100'}; % water exchange; + +BlockedExchanges = {'r_1663'; ... % 'bicarbonate exchange'; + 'r_4062'; ... % 'lipid backbone exchange'; + 'r_4064'}; ... % 'phosphate exchange'; + glucoseExchange = {'r_1714'}; % D-glucose exchange' - + uptakeRxnIndexes = findRxnIDs(model,desiredExchanges); glucoseExchangeIndex = findRxnIDs(model,glucoseExchange); +BlockedRxnIndex = findRxnIDs(model,BlockedExchanges); -if length(uptakeRxnIndexes) ~= 6 %5; +if length(uptakeRxnIndexes) ~= 7 %5; error('Not all exchange reactions were found.') end model.lb(uptakeRxnIndexes)=-1000; model.lb(glucoseExchangeIndex)=-10; +model.lb(BlockedRxnIndex)=0; +model.ub(BlockedRxnIndex)=0; end diff --git a/ComplementaryScripts/saveYeastModel.m b/ComplementaryScripts/saveYeastModel.m index e3005bd5..d702a3ab 100644 --- a/ComplementaryScripts/saveYeastModel.m +++ b/ComplementaryScripts/saveYeastModel.m @@ -15,6 +15,8 @@ function saveYeastModel(model,upDATE) if nargin < 2 upDATE = true; end +%set minimal media +model = minimal_Y6(model); %Get and change to the script folder, as all folders are relative to this %folder From 9be255edd2e4cbbb34d9c07c5e58124b994e6d62 Mon Sep 17 00:00:00 2001 From: FEIRANL Date: Wed, 5 Sep 2018 17:28:12 +0200 Subject: [PATCH 26/27] fix-rxn:set minimal media Set minimal media in the model by saveing the model again --- ModelFiles/dependencies.txt | 4 ++-- ModelFiles/txt/yeastGEM.txt | 12 ++++++------ ModelFiles/xml/yeastGEM.xml | 14 +++++++------- ModelFiles/yml/yeastGEM.yml | 12 ++++++------ README.md | 2 +- 5 files changed, 22 insertions(+), 22 deletions(-) diff --git a/ModelFiles/dependencies.txt b/ModelFiles/dependencies.txt index e5fb14da..4117f02f 100644 --- a/ModelFiles/dependencies.txt +++ b/ModelFiles/dependencies.txt @@ -1,7 +1,7 @@ -MATLAB 9.4.0.813654 (R2018a) +MATLAB 9.1.0.441655 (R2016b) libSBML 5.17.0 RAVEN_toolbox unknown -COBRA_toolbox commit ef3990e +COBRA_toolbox commit 75d530c SBML_level 3 SBML_version 1 fbc_version 2 diff --git a/ModelFiles/txt/yeastGEM.txt b/ModelFiles/txt/yeastGEM.txt index 8a3abc6c..3acd1127 100644 --- a/ModelFiles/txt/yeastGEM.txt +++ b/ModelFiles/txt/yeastGEM.txt @@ -2540,7 +2540,7 @@ r_1658 s_0969[c] -> s_0971[m] 0.00 1000.00 0.00 r_1659 s_0973[c] + s_0995[p] <=> s_0976[p] + s_0991[c] -1000.00 1000.00 0.00 r_1660 s_0434[c] <=> s_0438[n] -1000.00 1000.00 0.00 r_1661 s_0434[c] <=> s_0435[er] -1000.00 1000.00 0.00 -r_1663 s_0446[e] -> 0.00 1000.00 0.00 +r_1663 s_0446[e] -> 0.00 0.00 0.00 r_1664 s_0460[m] + s_0807[m] <=> s_0447[m] + s_0799[m] -1000.00 1000.00 0.00 r_1665 s_0461[n] + s_0808[n] <=> s_0448[n] + s_0800[n] -1000.00 1000.00 0.00 r_1667 s_0456[c] + s_0803[c] <=> s_0445[c] + s_0794[c] YNL036W -1000.00 1000.00 0.00 @@ -2586,7 +2586,7 @@ r_1710 s_0559[e] -> 0.00 1000.00 0.00 r_1711 s_0560[e] -> 0.00 1000.00 0.00 r_1712 s_0562[e] -> 0.00 1000.00 0.00 r_1713 s_0413[e] <=> s_0412[c] -1000.00 1000.00 0.00 -r_1714 s_0565[e] <=> -1.00 1000.00 0.00 +r_1714 s_0565[e] <=> -10.00 1000.00 0.00 r_1715 s_0572[e] -> 0.00 1000.00 0.00 r_1716 s_0576[e] -> 0.00 1000.00 0.00 r_1717 s_0562[e] <=> s_0561[c] -1000.00 1000.00 0.00 @@ -2829,7 +2829,7 @@ r_2003 s_1318[c] <=> s_1320[m] -1000.00 1000.00 0.00 r_2004 s_1032[c] -> s_1034[m] 0.00 1000.00 0.00 r_2005 s_1324[e] <=> -1000.00 1000.00 0.00 r_2008 s_1322[c] <=> s_1329[v] -1000.00 1000.00 0.00 -r_2020 s_1374[e] <=> -1000.00 1000.00 0.00 +r_2020 s_1374[e] -> 0.00 1000.00 0.00 r_2022 s_1384[c] <=> s_1385[m] -1000.00 1000.00 0.00 r_2023 s_1386[c] <=> s_1387[m] -1000.00 1000.00 0.00 r_2024 s_1390[e] -> 0.00 1000.00 0.00 @@ -2852,7 +2852,7 @@ r_2043 s_1418[e] -> 0.00 1000.00 0.00 r_2044 s_1425[e] -> 0.00 1000.00 0.00 r_2045 s_1039[c] <=> s_1042[m] -1000.00 1000.00 0.00 r_2046 s_1435[e] -> 0.00 1000.00 0.00 -r_2049 s_1438[e] <=> -1000.00 1000.00 0.00 +r_2049 s_1438[e] -> 0.00 1000.00 0.00 r_2050 s_0373[c] + s_1439[c] -> s_0529[c] + s_0794[c] + s_1180[c] 0.00 1000.00 0.00 r_2051 s_1440[e] -> 0.00 1000.00 0.00 r_2052 s_1443[e] -> 0.00 1000.00 0.00 @@ -3803,7 +3803,7 @@ r_4438 s_0794[c] + s_4060[c] <=> s_0802[v] + s_4061[v] -1000.00 1000.00 0.0 r_4439 s_0810[v] + s_4061[v] -> s_0996[v] + s_3839[v] 0.00 1000.00 0.00 r_4440 s_1029[c] <=> s_3758[v] -1000.00 1000.00 0.00 r_4441 s_1045[c] <=> s_4043[v] -1000.00 1000.00 0.00 -r_4442 s_4074[e] <=> -1000.00 1000.00 0.00 +r_4442 s_4074[e] -> 0.00 1000.00 0.00 r_4443 s_4095[e] <=> s_4094[c] -1000.00 1000.00 0.00 r_4444 s_0796[e] + s_4141[e] <=> s_0188[c] + s_0794[c] -1000.00 1000.00 0.00 r_4445 s_0796[e] + s_4142[e] <=> s_0260[c] + s_0794[c] -1000.00 1000.00 0.00 @@ -3855,7 +3855,7 @@ r_4490 s_0794[c] + s_1212[c] + s_4180[c] <=> s_1207[c] + s_1566[c] -1000.00 1 r_4491 s_0548[c] + s_0794[c] + s_1212[c] -> s_1207[c] + s_4181[c] 0.00 1000.00 0.00 r_4492 s_1198[c] + s_4181[c] -> s_0580[c] + s_0794[c] + s_1203[c] 0.00 1000.00 0.00 r_4493 s_4133[e] <=> s_4132[c] -1000.00 1000.00 0.00 -r_4494 s_4124[e] <=> -1000.00 1000.00 0.00 +r_4494 s_4124[e] -> 0.00 1000.00 0.00 r_4495 s_0389[c] + s_0803[c] -> s_0386[c] + s_1322[c] 0.00 1000.00 0.00 r_4496 s_4170[e] -> 0.00 1000.00 0.00 r_4497 s_4137[e] -> 0.00 1000.00 0.00 diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index e9078443..c473c655 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -49128,7 +49128,7 @@ - + @@ -147577,7 +147577,7 @@ - +

Confidence Level: NaN

@@ -148674,7 +148674,7 @@ - +

Confidence Level: NaN

@@ -154353,7 +154353,7 @@ - +

Confidence Level: NaN

@@ -154896,7 +154896,7 @@ - +

Confidence Level: NaN

@@ -180862,7 +180862,7 @@ - +

Confidence Level: 1

@@ -182407,7 +182407,7 @@ - +

Confidence Level: 1

diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index e5c8697a..289bd7b4 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -46721,7 +46721,7 @@ - metabolites: !!omap - s_0446: -1 - lower_bound: 0 - - upper_bound: 1000 + - upper_bound: 0 - annotation: !!omap - sbo: SBO:0000627 - !!omap @@ -47229,7 +47229,7 @@ - name: D-glucose exchange - metabolites: !!omap - s_0565: -1 - - lower_bound: -1 + - lower_bound: -10 - upper_bound: 1000 - annotation: !!omap - sbo: SBO:0000627 @@ -49831,7 +49831,7 @@ - name: potassium exchange - metabolites: !!omap - s_1374: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - annotation: !!omap - sbo: SBO:0000627 @@ -50113,7 +50113,7 @@ - name: sodium exchange - metabolites: !!omap - s_1438: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - annotation: !!omap - sbo: SBO:0000627 @@ -88703,7 +88703,7 @@ - name: cysteamine exchange - metabolites: !!omap - s_4074: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - annotation: !!omap - sbo: SBO:0000627 @@ -89405,7 +89405,7 @@ - name: methanol exchange - metabolites: !!omap - s_4124: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - annotation: !!omap - metanetx.reaction: MNXR98748 diff --git a/README.md b/README.md index 6c958bf1..626cc6b1 100644 --- a/README.md +++ b/README.md @@ -10,7 +10,7 @@ This repository contains the current consensus genome-scale metabolic model of _ **GEM Category:** Species; **Utilisation:** predictive simulation, multi-omics integrative analysis, _in silico_ strain design, model template; **Field:** metabolic-network reconstruction; **Type of Model:** curated, reconstruction; **Model Source:** [Yeast 7.6](https://sourceforge.net/projects/yeast/); **Taxonomy:** _Saccharomyces cerevisiae_; **Metabolic System:** General Metabolism; **Condition:** aerobic, glucose-limited, defined media, maximization of growth. -* Last update: 2018-08-30 +* Last update: 2018-09-05 * Main Model Descriptors: From 0e8cce676cd0b0b5099d7190dbecadf6ae424085 Mon Sep 17 00:00:00 2001 From: benjasanchez Date: Wed, 5 Sep 2018 19:15:26 +0200 Subject: [PATCH 27/27] fix-rxn.prop: D-glucose uptake + some formatting --- .../modelCuration/minimal_Y6.m | 41 ++++++++++--------- ComplementaryScripts/saveYeastModel.m | 7 +++- ModelFiles/dependencies.txt | 4 +- ModelFiles/txt/yeastGEM.txt | 2 +- ModelFiles/xml/yeastGEM.xml | 4 +- ModelFiles/yml/yeastGEM.yml | 2 +- 6 files changed, 33 insertions(+), 27 deletions(-) diff --git a/ComplementaryScripts/modelCuration/minimal_Y6.m b/ComplementaryScripts/modelCuration/minimal_Y6.m index a7581523..1a226b66 100755 --- a/ComplementaryScripts/modelCuration/minimal_Y6.m +++ b/ComplementaryScripts/modelCuration/minimal_Y6.m @@ -8,35 +8,38 @@ % start with a clean slate: set all exchange reactions to upper bound = 1000 % and lower bound = 0 (ie, unconstrained excretion, no uptake) -%Feiran Li 2018.09.25 +%Feiran Li 2018.09.05 + exchangeRxns = findExcRxns(model); model.lb(exchangeRxns) = 0; model.ub(exchangeRxns) = 1000; -desiredExchanges = {'r_1654'; ... % 'ammonium exchange'; - 'r_1992'; ... % 'oxygen exchange'; - 'r_2005'; ... % 'phosphate exchange'; - 'r_2060'; ... % 'sulphate exchange'; - 'r_1861'; ... % iron for test of expanded biomass def; - 'r_1832'; ... % hydrogen exchange; - 'r_2100'}; % water exchange; -BlockedExchanges = {'r_1663'; ... % 'bicarbonate exchange'; - 'r_4062'; ... % 'lipid backbone exchange'; - 'r_4064'}; ... % 'phosphate exchange'; +desiredExchanges = {'r_1654'; ... % ammonium exchange + 'r_1992'; ... % oxygen exchange + 'r_2005'; ... % phosphate exchange + 'r_2060'; ... % sulphate exchange + 'r_1861'; ... % iron exchange, for test of expanded biomass def + 'r_1832'; ... % hydrogen exchange + 'r_2100'}; % water exchange + +blockedExchanges = {'r_1663'; ... % bicarbonate exchange + 'r_4062'; ... % lipid backbone exchange + 'r_4064'}; % lipid chain exchange -glucoseExchange = {'r_1714'}; % D-glucose exchange' +glucoseExchange = {'r_1714'}; % D-glucose exchange -uptakeRxnIndexes = findRxnIDs(model,desiredExchanges); +uptakeRxnIndexes = findRxnIDs(model,desiredExchanges); glucoseExchangeIndex = findRxnIDs(model,glucoseExchange); -BlockedRxnIndex = findRxnIDs(model,BlockedExchanges); +BlockedRxnIndex = findRxnIDs(model,blockedExchanges); -if length(uptakeRxnIndexes) ~= 7 %5; +if length(uptakeRxnIndexes) ~= 7 error('Not all exchange reactions were found.') end -model.lb(uptakeRxnIndexes)=-1000; -model.lb(glucoseExchangeIndex)=-10; +model.lb(uptakeRxnIndexes) = -1000; +model.lb(glucoseExchangeIndex) = -1; + +model.lb(BlockedRxnIndex) = 0; +model.ub(BlockedRxnIndex) = 0; -model.lb(BlockedRxnIndex)=0; -model.ub(BlockedRxnIndex)=0; end diff --git a/ComplementaryScripts/saveYeastModel.m b/ComplementaryScripts/saveYeastModel.m index d702a3ab..c872e2cc 100644 --- a/ComplementaryScripts/saveYeastModel.m +++ b/ComplementaryScripts/saveYeastModel.m @@ -15,14 +15,17 @@ function saveYeastModel(model,upDATE) if nargin < 2 upDATE = true; end -%set minimal media -model = minimal_Y6(model); %Get and change to the script folder, as all folders are relative to this %folder scriptFolder = fileparts(which(mfilename)); currentDir = cd(scriptFolder); +%Set minimal media +cd modelCuration +model = minimal_Y6(model); +cd .. + %Delete model.grRules (redundant and possibly conflicting with model.rules): if isfield(model,'grRules') model = rmfield(model,'grRules'); diff --git a/ModelFiles/dependencies.txt b/ModelFiles/dependencies.txt index 4117f02f..341091c9 100644 --- a/ModelFiles/dependencies.txt +++ b/ModelFiles/dependencies.txt @@ -1,6 +1,6 @@ -MATLAB 9.1.0.441655 (R2016b) +MATLAB 9.4.0.813654 (R2018a) libSBML 5.17.0 -RAVEN_toolbox unknown +RAVEN_toolbox 2.0.2 COBRA_toolbox commit 75d530c SBML_level 3 SBML_version 1 diff --git a/ModelFiles/txt/yeastGEM.txt b/ModelFiles/txt/yeastGEM.txt index 3acd1127..70ebd3a2 100644 --- a/ModelFiles/txt/yeastGEM.txt +++ b/ModelFiles/txt/yeastGEM.txt @@ -2586,7 +2586,7 @@ r_1710 s_0559[e] -> 0.00 1000.00 0.00 r_1711 s_0560[e] -> 0.00 1000.00 0.00 r_1712 s_0562[e] -> 0.00 1000.00 0.00 r_1713 s_0413[e] <=> s_0412[c] -1000.00 1000.00 0.00 -r_1714 s_0565[e] <=> -10.00 1000.00 0.00 +r_1714 s_0565[e] <=> -1.00 1000.00 0.00 r_1715 s_0572[e] -> 0.00 1000.00 0.00 r_1716 s_0576[e] -> 0.00 1000.00 0.00 r_1717 s_0562[e] <=> s_0561[c] -1000.00 1000.00 0.00 diff --git a/ModelFiles/xml/yeastGEM.xml b/ModelFiles/xml/yeastGEM.xml index c473c655..5ec34031 100644 --- a/ModelFiles/xml/yeastGEM.xml +++ b/ModelFiles/xml/yeastGEM.xml @@ -49128,7 +49128,7 @@ - + @@ -148674,7 +148674,7 @@ - +

Confidence Level: NaN

diff --git a/ModelFiles/yml/yeastGEM.yml b/ModelFiles/yml/yeastGEM.yml index 289bd7b4..871ba080 100644 --- a/ModelFiles/yml/yeastGEM.yml +++ b/ModelFiles/yml/yeastGEM.yml @@ -47229,7 +47229,7 @@ - name: D-glucose exchange - metabolites: !!omap - s_0565: -1 - - lower_bound: -10 + - lower_bound: -1 - upper_bound: 1000 - annotation: !!omap - sbo: SBO:0000627