diff --git a/data/testResults/README.md b/data/testResults/README.md index 3219f11b..7d79c2be 100644 --- a/data/testResults/README.md +++ b/data/testResults/README.md @@ -4,7 +4,7 @@ The file here contains results from the [MACAW](https://github.com/Devlin-Moyer/ The test results shown here were obtained by the GitHub Actions run in: -- **PR #883** (MACAW) +- **PR #939** (MACAW) - **PR #883** (gene essentiality) The results will be updated by any subsequent pull request. Summary results are shown as a comment in the corresponding pull request. diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml index c18e9544..78429615 100644 --- a/model/Human-GEM.yml +++ b/model/Human-GEM.yml @@ -263003,9 +263003,6 @@ - !!omap - id: "ENSG00000116791" - name: "CRYZ" - - !!omap - - id: "ENSG00000116882" - - name: "HAO2" - !!omap - id: "ENSG00000116906" - name: "GNPAT" @@ -263417,9 +263414,6 @@ - !!omap - id: "ENSG00000124299" - name: "PEPD" - - !!omap - - id: "ENSG00000124302" - - name: "CHST8" - !!omap - id: "ENSG00000124356" - name: "STAMBP" @@ -263948,9 +263942,6 @@ - !!omap - id: "ENSG00000133027" - name: "PEMT" - - !!omap - - id: "ENSG00000133048" - - name: "CHI3L1" - !!omap - id: "ENSG00000133056" - name: "PIK3C2B" @@ -266096,9 +266087,6 @@ - !!omap - id: "ENSG00000163659" - name: "TIPARP" - - !!omap - - id: "ENSG00000163684" - - name: "RPP14" - !!omap - id: "ENSG00000163686" - name: "ABHD6" @@ -267272,9 +267260,6 @@ - !!omap - id: "ENSG00000175198" - name: "PCCA" - - !!omap - - id: "ENSG00000175229" - - name: "GAL3ST3" - !!omap - id: "ENSG00000175264" - name: "CHST1" diff --git a/model/genes.tsv b/model/genes.tsv index fc39600c..26405529 100644 --- a/model/genes.tsv +++ b/model/genes.tsv @@ -884,7 +884,6 @@ "ENSG00000116761" "ENST00000411986;ENST00000370938;ENST00000464926;ENST00000346806;ENST00000482383" "ENSP00000413407;ENSP00000359976;ENSP00000311554" "P32929" "CTH" "1491" "cystathionine gamma-lyase" "" "Cytosol" "SwissProt" "ENSG00000116771" "ENST00000375826" "ENSP00000364986" "Q9BSE5" "AGMAT" "79814" "agmatinase" "FLJ23384" "Mitochondria" "DeepLoc2" "ENSG00000116791" "ENST00000370872;ENST00000340866;ENST00000492102;ENST00000417775;ENST00000370871;ENST00000370870;ENST00000441120" "ENSP00000359909;ENSP00000339399;ENSP00000399805;ENSP00000359908;ENSP00000359907;ENSP00000404289" "Q08257" "CRYZ" "1429" "crystallin zeta" "" "Cytosol" "SwissProt;CellAtlas" -"ENSG00000116882" "ENST00000457318;ENST00000361035;ENST00000325945;ENST00000482991;ENST00000622548" "ENSP00000393955;ENSP00000354314;ENSP00000316339;ENSP00000483507" "Q9NYQ3" "HAO2" "51179" "hydroxyacid oxidase 2" "GIG16;HAOX2" "Peroxisome;Cytosol" "SwissProt;CellAtlas" "ENSG00000116906" "ENST00000436239;ENST00000366647;ENST00000416000;ENST00000644483;ENST00000492459;ENST00000469332" "ENSP00000402811;ENSP00000355607;ENSP00000411640;ENSP00000496537" "O15228" "GNPAT" "8443" "glyceronephosphate O-acyltransferase" "DAP-AT;DAPAT;DHAPAT" "Peroxisome" "SwissProt" "ENSG00000116981" "ENST00000235628" "ENSP00000235628" "Q9BXI3" "NT5C1A" "84618" "5'-nucleotidase, cytosolic IA" "CN-I;CN-IA;CN1;CN1A;MGC119199;MGC119201" "Cytosol" "SwissProt" "ENSG00000116984" "ENST00000680454;ENST00000366577;ENST00000674797;ENST00000652435;ENST00000679569;ENST00000650888;ENST00000463959;ENST00000535889;ENST00000651455;ENST00000681102;ENST00000679842;ENST00000681177;ENST00000681937;ENST00000366576;ENST00000470570;ENST00000681813;ENST00000652483" "ENSP00000355536;ENSP00000502299;ENSP00000505932;ENSP00000498393;ENSP00000505498;ENSP00000441845;ENSP00000498963;ENSP00000505600;ENSP00000506109;ENSP00000506327;ENSP00000355535" "Q99707" "MTR" "4548" "5-methyltetrahydrofolate-homocysteine methyltransferase" "cblG" "Cytosol" "SwissProt;CellAtlas" @@ -1022,7 +1021,6 @@ "ENSG00000124253" "ENST00000467047;ENST00000319441;ENST00000475833;ENST00000498194;ENST00000470051;ENST00000485958" "ENSP00000319814" "P35558" "PCK1" "5105" "phosphoenolpyruvate carboxykinase 1" "PEPCK-C" "Cytosol;Endoplasmic reticulum" "SwissProt" "ENSG00000124275" "ENST00000507837;ENST00000502509;ENST00000511639;ENST00000513439;ENST00000264668;ENST00000508047;ENST00000510279;ENST00000514220;ENST00000511461;ENST00000503550;ENST00000440940;ENST00000514369;ENST00000502550;ENST00000506877;ENST00000512217;ENST00000510525;ENST00000508890;ENST00000508101;ENST00000509961;ENST00000512311;ENST00000507414;ENST00000507202;ENST00000508354;ENST00000506115;ENST00000509379" "ENSP00000426710;ENSP00000264668;ENSP00000423139;ENSP00000427200;ENSP00000423863;ENSP00000424719;ENSP00000424644;ENSP00000402510;ENSP00000426132;ENSP00000424599;ENSP00000427416;ENSP00000421318;ENSP00000421991" "Q9UBK8" "MTRR" "4552" "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" "cblE" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000124299" "ENST00000593085;ENST00000244137;ENST00000588328;ENST00000591968;ENST00000397032;ENST00000436370;ENST00000651901;ENST00000590731;ENST00000609145;ENST00000588719;ENST00000651646;ENST00000590755;ENST00000590408;ENST00000593163" "ENSP00000244137;ENSP00000468516;ENSP00000380226;ENSP00000391890;ENSP00000498922;ENSP00000498950;ENSP00000476667;ENSP00000476869" "P12955" "PEPD" "5184" "peptidase D" "" "Nucleus" "CellAtlas" -"ENSG00000124302" "ENST00000591231;ENST00000438847;ENST00000604556;ENST00000262622;ENST00000650847;ENST00000434302" "ENSP00000467012;ENSP00000393879;ENSP00000262622;ENSP00000499084;ENSP00000392604" "Q9H2A9" "CHST8" "64377" "carbohydrate sulfotransferase 8" "GALNAC-4-ST1" "Golgi apparatus" "SwissProt" "ENSG00000124356" "ENST00000339566;ENST00000683349;ENST00000682157;ENST00000683036;ENST00000683317;ENST00000682847;ENST00000684095;ENST00000684337;ENST00000683247;ENST00000682329;ENST00000682683;ENST00000683149;ENST00000682851;ENST00000683728;ENST00000394070;ENST00000409707;ENST00000684585;ENST00000683434;ENST00000682352;ENST00000684697;ENST00000682592;ENST00000683718;ENST00000683518;ENST00000424659;ENST00000536064;ENST00000684200;ENST00000684355;ENST00000684774;ENST00000478946;ENST00000682423;ENST00000683465;ENST00000682998;ENST00000682799;ENST00000684703;ENST00000683016;ENST00000684174;ENST00000684716;ENST00000394073;ENST00000684671;ENST00000682848;ENST00000683877;ENST00000683530;ENST00000683027;ENST00000683304;ENST00000684321;ENST00000683852;ENST00000684312;ENST00000682379;ENST00000683205;ENST00000682784;ENST00000682351;ENST00000683818;ENST00000684426;ENST00000683582;ENST00000452725;ENST00000682105;ENST00000683594;ENST00000682387;ENST00000682747;ENST00000683417;ENST00000683928;ENST00000683391;ENST00000684758;ENST00000682558;ENST00000432295;ENST00000683902;ENST00000486458;ENST00000683314;ENST00000682271;ENST00000683408;ENST00000487811" "ENSP00000344742;ENSP00000507807;ENSP00000507848;ENSP00000507639;ENSP00000507092;ENSP00000507864;ENSP00000506845;ENSP00000508310;ENSP00000507237;ENSP00000507540;ENSP00000507371;ENSP00000507079;ENSP00000377633;ENSP00000386548;ENSP00000507054;ENSP00000507622;ENSP00000508197;ENSP00000506855;ENSP00000508170;ENSP00000507037;ENSP00000506865;ENSP00000390921;ENSP00000443502;ENSP00000507468;ENSP00000507974;ENSP00000508267;ENSP00000508259;ENSP00000507643;ENSP00000507046;ENSP00000507089;ENSP00000507569;ENSP00000508373;ENSP00000508172;ENSP00000377636;ENSP00000507882;ENSP00000506775;ENSP00000507446;ENSP00000506920;ENSP00000508114;ENSP00000507156;ENSP00000507717;ENSP00000506958;ENSP00000507081;ENSP00000507523;ENSP00000506833;ENSP00000507658;ENSP00000507614;ENSP00000506892;ENSP00000507182;ENSP00000507459;ENSP00000508186;ENSP00000507770;ENSP00000507241;ENSP00000506772;ENSP00000507279;ENSP00000507014;ENSP00000413874;ENSP00000507096" "O95630" "STAMBP" "10617" "STAM binding protein" "AMSH" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000124357" "ENST00000531799;ENST00000497690;ENST00000455662;ENST00000531934;ENST00000455197;ENST00000418807;ENST00000443872;ENST00000443938;ENST00000484984;ENST00000244204;ENST00000493102;ENST00000450272;ENST00000465105;ENST00000480411;ENST00000475709;ENST00000533981;ENST00000472519;ENST00000489309;ENST00000464638;ENST00000428360;ENST00000524736;ENST00000479854;ENST00000529236;ENST00000478659;ENST00000524537;ENST00000490998;ENST00000468601;ENST00000498022;ENST00000613852" "ENSP00000389087;ENSP00000436326;ENSP00000408550;ENSP00000396070;ENSP00000404531;ENSP00000411846;ENSP00000244204;ENSP00000400941;ENSP00000435207;ENSP00000435437;ENSP00000431204;ENSP00000437192;ENSP00000477639" "Q9UJ70" "NAGK" "55577" "N-acetylglucosamine kinase" "GNK" "Cytosol;Nucleus" "CellAtlas" "ENSG00000124370" "ENST00000413592;ENST00000244217;ENST00000462609;ENST00000494660;ENST00000486135" "ENSP00000391140;ENSP00000244217;ENSP00000437361;ENSP00000441569" "Q96PE7" "MCEE" "84693" "methylmalonyl-CoA epimerase" "GLOD2;MCE" "Mitochondria;Nucleus" "SwissProt;CellAtlas" @@ -1199,7 +1197,6 @@ "ENSG00000132915" "ENST00000255266;ENST00000508173;ENST00000512670;ENST00000613228;ENST00000617647" "ENSP00000255266;ENSP00000478060;ENSP00000482774" "P16499" "PDE6A" "5145" "phosphodiesterase 6A" "PDEA;RP43" "Cytosol" "SwissProt" "ENSG00000132958" "ENST00000382978;ENST00000462409;ENST00000390680;ENST00000400103;ENST00000400230;ENST00000255310" "ENSP00000372438;ENSP00000432402;ENSP00000375098;ENSP00000382974;ENSP00000383089;ENSP00000255310" "Q6XPS3" "TPTE2" "93492" "transmembrane phosphoinositide 3-phosphatase and tensin homolog 2" "TPIP" "Endoplasmic reticulum;Golgi apparatus;Cytosol" "SwissProt;CellAtlas" "ENSG00000133027" "ENST00000582268;ENST00000484838;ENST00000490392;ENST00000395782;ENST00000395783;ENST00000435340;ENST00000255389;ENST00000395781;ENST00000477595;ENST00000580147;ENST00000421096;ENST00000472446;ENST00000461404" "ENSP00000379128;ENSP00000379129;ENSP00000391288;ENSP00000255389;ENSP00000379127;ENSP00000463112;ENSP00000463713" "Q9UBM1" "PEMT" "10400" "phosphatidylethanolamine N-methyltransferase" "PEMPT;PEMT2" "Endoplasmic reticulum;Mitochondria;Cytosol" "SwissProt;CellAtlas" -"ENSG00000133048" "ENST00000473185;ENST00000255409;ENST00000404436;ENST00000478742;ENST00000472064" "ENSP00000255409;ENSP00000385350" "P36222" "CHI3L1" "1116" "chitinase 3 like 1" "GP39;YK-40;YKL40" "Endoplasmic reticulum;Golgi apparatus;Cytosol" "SwissProt;CellAtlas" "ENSG00000133056" "ENST00000367187;ENST00000424712;ENST00000684373;ENST00000683234;ENST00000462752;ENST00000479079;ENST00000496872;ENST00000415899;ENST00000367184;ENST00000429009" "ENSP00000356155;ENSP00000400561;ENSP00000507222;ENSP00000401795;ENSP00000356152;ENSP00000409554" "O00750" "PIK3C2B" "5287" "phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta" "C2-PI3K;PI3K-C2beta" "Endoplasmic reticulum;Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000133063" "ENST00000484834;ENST00000479483;ENST00000367229;ENST00000491855;ENST00000255427;ENST00000503786;ENST00000506427;ENST00000513472;ENST00000460619" "ENSP00000356198;ENSP00000423778;ENSP00000255427;ENSP00000421617" "Q13231" "CHIT1" "1118" "chitinase 1" "CHI3;CHIT" "Lysosome" "SwissProt" "ENSG00000133065" "ENST00000367137;ENST00000468057;ENST00000484228;ENST00000484000" "ENSP00000356105" "Q8IVJ1" "SLC41A1" "254428" "solute carrier family 41 member 1" "MgtE" "Mitochondria" "CellAtlas" @@ -1908,7 +1905,6 @@ "ENSG00000163631" "ENST00000441319;ENST00000295897;ENST00000510166;ENST00000515133;ENST00000415165;ENST00000514786;ENST00000476441;ENST00000503124;ENST00000509063;ENST00000401494;ENST00000505649;ENST00000511370;ENST00000507673;ENST00000484992;ENST00000504043;ENST00000486939;ENST00000508932;ENST00000495173;ENST00000621085;ENST00000621628" "ENSP00000392541;ENSP00000295897;ENSP00000401820;ENSP00000423727;ENSP00000421027;ENSP00000422784;ENSP00000384695;ENSP00000426179;ENSP00000483421;ENSP00000480485" "P02768" "ALB" "213" "albumin" "" "Endoplasmic reticulum;Golgi apparatus" "CellAtlas" "ENSG00000163655" "ENST00000496455;ENST00000295920;ENST00000476145" "ENSP00000419851;ENSP00000295920" "P49915" "GMPS" "8833" "guanine monophosphate synthase" "GATD7" "Cytosol" "SwissProt;CellAtlas" "ENSG00000163659" "ENST00000486483;ENST00000295924;ENST00000461166;ENST00000473702;ENST00000481853;ENST00000495891;ENST00000542783" "ENSP00000418757;ENSP00000295924;ENSP00000420612;ENSP00000419982;ENSP00000418829;ENSP00000420141;ENSP00000438345" "Q7Z3E1" "TIPARP" "25976" "TCDD inducible poly(ADP-ribose) polymerase" "ARTD14;DDF1;DKFZP434J214;DKFZp686N0351;PARP-1;PARP-7;PARP7;pART14;RM1" "Nucleus" "SwissProt" -"ENSG00000163684" "ENST00000295959;ENST00000461797;ENST00000445193;ENST00000466547;ENST00000463550;ENST00000462046" "ENSP00000295959;ENSP00000412894;ENSP00000419909" "O95059" "RPP14" "11102" "ribonuclease P/MRP subunit p14" "P14" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000163686" "ENST00000295962;ENST00000478253;ENST00000475982;ENST00000463756;ENST00000485900;ENST00000470440;ENST00000480457" "ENSP00000295962;ENSP00000420315;ENSP00000418209;ENSP00000420408;ENSP00000418934" "Q9BV23" "ABHD6" "57406" "abhydrolase domain containing 6, acylglycerol lipase" "" "Nucleus;Lysosome" "SwissProt;CellAtlas" "ENSG00000163719" "ENST00000353332;ENST00000420925;ENST00000447144;ENST00000430020;ENST00000296003;ENST00000351233;ENST00000416864;ENST00000437997;ENST00000480578;ENST00000449543;ENST00000414996;ENST00000431250;ENST00000606184" "ENSP00000323462;ENSP00000401993;ENSP00000410761;ENSP00000392690;ENSP00000296003;ENSP00000334070;ENSP00000412644;ENSP00000408813;ENSP00000411417;ENSP00000392935;ENSP00000388746" "Q8NCE2" "MTMR14" "64419" "myotubularin related protein 14" "C3orf29;FLJ22405;FLJ90311;hEDTP;hJumpy" "Cytosol;Nucleus" "SwissProt" "ENSG00000163738" "ENST00000429519;ENST00000490698;ENST00000475291;ENST00000429335;ENST00000433372;ENST00000423607;ENST00000395759;ENST00000461101;ENST00000325278;ENST00000359107;ENST00000484725;ENST00000492183;ENST00000461856;ENST00000465255;ENST00000490128" "ENSP00000391327;ENSP00000409391;ENSP00000405692;ENSP00000387614;ENSP00000379108;ENSP00000321984;ENSP00000352012" "Q9H903" "MTHFD2L" "441024" "methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like" "MGC72244" "Inner mitochondria" "SwissProt" @@ -2294,7 +2290,6 @@ "ENSG00000175066" "ENST00000392993;ENST00000492097;ENST00000480757;ENST00000460515;ENST00000463349;ENST00000486459;ENST00000460630;ENST00000460544;ENST00000487672;ENST00000466685;ENST00000472759;ENST00000489085" "ENSP00000418001;ENSP00000420312;ENSP00000419031;ENSP00000417153;ENSP00000420593;ENSP00000418239" "Q6ZS86" "GK5" "256356" "glycerol kinase 5" "MGC40579" "Cytosol;Nucleus" "CellAtlas" "ENSG00000175164" "ENST00000679909;ENST00000680600;ENST00000453660;ENST00000647353;ENST00000611156;ENST00000538324;ENST00000651471" "ENSP00000506089;ENSP00000483265;ENSP00000483018" "A0A087X009" "ABO" "28" "ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase" "A3GALNT;A3GALT1" "Golgi apparatus" "DeepLoc2" "ENSG00000175198" "ENST00000376285;ENST00000647303;ENST00000637358;ENST00000636420;ENST00000636366;ENST00000636475;ENST00000637657;ENST00000485946;ENST00000424527;ENST00000443601;ENST00000458283;ENST00000413170;ENST00000621936;ENST00000428969;ENST00000376286;ENST00000376279" "ENSP00000365462;ENSP00000495663;ENSP00000489804;ENSP00000490290;ENSP00000490939;ENSP00000490843;ENSP00000489974;ENSP00000396050;ENSP00000400740;ENSP00000390850;ENSP00000411194;ENSP00000399413;ENSP00000365463;ENSP00000365456" "P05165" "PCCA" "5095" "propionyl-CoA carboxylase subunit alpha" "" "Mitochondria" "SwissProt;CellAtlas" -"ENSG00000175229" "ENST00000312006;ENST00000527878;ENST00000527048" "ENSP00000308591;ENSP00000434829" "Q96A11" "GAL3ST3" "89792" "galactose-3-O-sulfotransferase 3" "GAL3ST2" "Golgi apparatus" "SwissProt" "ENSG00000175264" "ENST00000308064;ENST00000533673;ENST00000531322" "ENSP00000309270" "O43916" "CHST1" "8534" "carbohydrate sulfotransferase 1" "C6ST;KSGal6ST" "Golgi apparatus" "SwissProt" "ENSG00000175283" "ENST00000372586" "ENSP00000361667" "Q9UPQ8" "DOLK" "22845" "dolichol kinase" "DK1;KIAA1094;TMEM15" "Endoplasmic reticulum;Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000175309" "ENST00000308158;ENST00000481436;ENST00000481811;ENST00000489262;ENST00000474052;ENST00000393488;ENST00000493197;ENST00000494126;ENST00000510991;ENST00000476487;ENST00000506045;ENST00000510913;ENST00000504096;ENST00000514424;ENST00000323594;ENST00000506001;ENST00000511716;ENST00000476170" "ENSP00000310978;ENSP00000423806;ENSP00000377128;ENSP00000425425;ENSP00000427444;ENSP00000424608;ENSP00000321290;ENSP00000421810" "Q8IUZ5" "PHYKPL" "85007" "5-phosphohydroxy-L-lysine phospho-lyase" "AGXT2L2;MGC15875" "Mitochondria" "SwissProt;CellAtlas"