diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml
index c6a46e87..250ee363 100644
--- a/model/Human-GEM.yml
+++ b/model/Human-GEM.yml
@@ -218228,7 +218228,7 @@
           - MAM02553m: 1
       - lower_bound: 0
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000111275 or ENSG00000137124 or ENSG00000159423"
+      - gene_reaction_rule: "ENSG00000111275 or ENSG00000137124"
       - rxnNotes: ""
       - rxnFrom: "Recon3D"
       - eccodes: "1.5.1.12"