diff --git a/data/deprecatedIdentifiers/deprecatedReactions.tsv b/data/deprecatedIdentifiers/deprecatedReactions.tsv index eddba6e4..183ebeef 100644 --- a/data/deprecatedIdentifiers/deprecatedReactions.tsv +++ b/data/deprecatedIdentifiers/deprecatedReactions.tsv @@ -207,7 +207,15 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR01666" "" "" "" "" "R-HSA-193399" "HMR_1666" "MNXR125298" "HMR_1666" "RCR20514" "" 0 "RHEA:72683" "RHEA:72683" "HMR_1666" "MAR01458" "" "HSD17B4x" "" "" "" "HSD17B4x" "MNXR100720" "" "" "" 0 "" "" "HSD17B4x" "MAR01651" "R04812" "" "RE3250M" "" "" "HMR_1651" "" "HMR_1651" "RCR12831" "" 0 "" "" "HMR_1651" +"MAR01639" "" "" "RE3247X;RE3247M" "r0706" "R-HSA-192335" "RE3247X;r0706;HMR_1637;RE3247M" "MNXR105369;MNXR124225" "HMR_1639;HMR_1637" "RCR10917;RCR13607" "" 0 "" "" "HMR_1639;HMR_1637;MAR01637" +"MAR03301" "" "" "RE1516X" "" "" "" "" "HMR_3301" "RCR12606" "" 0 "" "" "HMR_3301" +"MAR03306" "" "" "RE1517X" "" "" "" "" "HMR_3306" "RCR12610" "" 0 "" "" "HMR_3306" +"MAR03311" "" "" "RE1518X" "" "" "" "" "HMR_3311" "RCR14519" "" 0 "" "" "HMR_3311" +"MAR04966" "" "FAOXC101C102x" "" "" "" "FAOXC101C102x" "" "" "" "" 0 "" "" "FAOXC101C102x" +"MAR03364" "" "" "RE2913X" "" "" "" "" "HMR_3364" "RCR12576" "" 0 "" "" "HMR_3364" +"MAR03369" "" "" "RE2914X" "" "" "" "" "HMR_3369" "RCR12580" "" 0 "" "" "HMR_3369" "MAR09887" "" "GLNB0AT3tc" "" "" "" "GLNB0AT3tc" "" "" "" "" 0 "" "" "GLNB0AT3tc" +"MAR00059" "" "ACOX22x" "" "" "" "ACOX22x" "MNXR95389" "" "" "" 0 "" "" "ACOX22x" "MAR00024" "" "" "" "" "" "HMR_0024" "" "HMR_0024" "RCR13367" "" 0 "" "" "HMR_0024" "MAR00025" "" "" "" "" "" "HMR_0025;HMR_0030" "" "HMR_0025;HMR_0030" "RCR20226;RCR20227" "" 0 "" "" "HMR_0025;HMR_0030;MAR00030" "MAR00026" "" "" "" "" "" "HMR_0026" "" "HMR_0026" "RCR21051" "" 0 "" "" "HMR_0026" @@ -224,3 +232,12 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR02006" "" "CPS_m" "" "" "" "r0034" "" "" "" "" 0 "" "" "r0034" "MAR06400" "R07768" "" "R07768C" "" "" "HMR_6400" "MNXR111356" "HMR_6400" "RCR11944" "" 0 "" "" "HMR_6400" "MAR06401" "R07769" "" "R07769C" "" "" "HMR_6401" "MNXR111357" "HMR_6401" "RCR11945" "" 0 "" "" "HMR_6401" +"MAR03940" "R01795" "PHETHPTOX" "R01795C" "r0399" "" "r0399" "MNXR102632;MNXR107174" "HMR_3940" "RCR11388" "" 0 "" "RHEA:30787" "HMR_3940" +"MAR07785" "" "ATPtx" "" "" "" "ATPtx" "MNXR96140" "HMR_7785" "RCR20040" "" 0 "" "" "HMR_7785" +"MAR07775" "" "NADHtpu" "" "" "" "NADHtpu;NADtpu" "MNXR101881" "HMR_7775" "RCR20024" "" 0 "" "" "HMR_7775" +"MAR07788" "" "FADH2tx" "" "" "" "FADH2tx" "MNXR99212" "HMR_7788" "RCR20202" "" 0 "" "" "HMR_7788" +"MAR04915" "" "COAtp" "" "r0864" "" "COAtp" "MNXR96815" "HMR_4915" "RCR20004" "" 0 "" "" "HMR_4915" +"MAR07771" "" "NADtpu" "" "" "" "NADtx" "MNXR101881" "HMR_7771" "RCR20023" "" 0 "" "" "HMR_7771" +"MAR07782" "" "ADPtx" "" "" "" "ADPtx" "MNXR95484" "HMR_7782" "RCR20201" "" 0 "" "" "HMR_7782" +"MAR07783" "" "AMPtp" "" "" "" "AMPtp" "MNXR95830" "HMR_7783" "RCR20046" "" 0 "" "" "HMR_7783" +"MAR07790" "" "FADtx" "" "" "" "FADtx" "MNXR99217" "HMR_7790" "RCR20203" "" 0 "" "" "HMR_7790" diff --git a/data/metabolicTasks/metabolicTasks_CellfieConsensus.txt b/data/metabolicTasks/metabolicTasks_CellfieConsensus.txt index 683f65e1..2a43215d 100644 --- a/data/metabolicTasks/metabolicTasks_CellfieConsensus.txt +++ b/data/metabolicTasks/metabolicTasks_CellfieConsensus.txt @@ -211,7 +211,7 @@ NAD+[m] 1 1 CO2[m] 1 1 NADH[m] 1 1 34 Synthesis of fructose-6-phosphate from erythrose-4-phosphate (HMP shunt) fructose-6-phosphate[c] 1 1 erythrose-4-phosphate[c] 1 1 - GAP[c] 1 1 D-xylulose-5-phosphate[c] 1 1 + D-glyceraldehyde 3-phosphate[c] 1 1 D-xylulose-5-phosphate[c] 1 1 35 Synthesis of ribose-5-phosphate glucose[c] 1 1 ribose-5-phosphate[c] 1 1 ATP[c] 1 1 ADP[c] 1 1 NADP+[c] 2 2 H+[c] 3 3 @@ -226,7 +226,7 @@ 38 Glycogen degradation glycogenin G4G7[c] 1 1 glucose[c] 8 Pi[c] 3 NA[c] 1 1 H2O[c] 8 glucose-1-phosphate[c] 3 - 39 Fructose degradation (to glucose-3-phosphate) fructose[c] 1 1 GAP[c] 2 2 + 39 Fructose degradation (to glucose-3-phosphate) fructose[c] 1 1 D-glyceraldehyde 3-phosphate[c] 2 2 ATP[c] 2 2 ADP[c] 2 2 H+[c] 2 2 40 Fructose to glucose conversion (via fructose-6-phosphate) fructose[c] 1 1 glucose[c] 1 1 diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml index 5a78bdcc..764fcd6a 100644 --- a/model/Human-GEM.yml +++ b/model/Human-GEM.yml @@ -24961,6 +24961,14 @@ - charge: -2 - inchis: "" - metFrom: "HMRdatabase" + - !!omap + - id: "MAM01828x" + - name: "FMN" + - compartment: "x" + - formula: "C17H19N4O9P" + - charge: -2 + - inchis: "" + - metFrom: "" - !!omap - id: "MAM01829g" - name: "fn2m2masn" @@ -72746,8 +72754,8 @@ - name: "Xanthine:oxygen oxidoreductase" - metabolites: !!omap - MAM02040x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03120x: 1 - MAM03148x: -1 - lower_bound: 0 @@ -73250,9 +73258,9 @@ - name: "Hypoxanthine:oxygen oxidoreductase" - metabolites: !!omap - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02159x: -1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03148x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -77634,9 +77642,9 @@ - MAM01641x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02633x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -78509,9 +78517,9 @@ - metabolites: !!omap - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02925x: 1 - MAM02926x: -1 - lower_bound: 0 @@ -78572,9 +78580,9 @@ - metabolites: !!omap - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02924x: 1 - MAM02925x: -1 - lower_bound: 0 @@ -78692,9 +78700,9 @@ - metabolites: !!omap - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02921x: 1 - MAM02923x: -1 - lower_bound: 0 @@ -78755,9 +78763,9 @@ - metabolites: !!omap - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02922x: 1 - MAM02923x: -1 - lower_bound: 0 @@ -78818,9 +78826,9 @@ - metabolites: !!omap - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02920x: 1 - MAM02921x: -1 - lower_bound: 0 @@ -78881,9 +78889,9 @@ - metabolites: !!omap - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02920x: 1 - MAM02922x: -1 - lower_bound: 0 @@ -79017,9 +79025,9 @@ - metabolites: !!omap - MAM01250x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02504x: -1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02923x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -79076,9 +79084,9 @@ - metabolites: !!omap - MAM01250x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02503x: -1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02812x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -79116,10 +79124,10 @@ - metabolites: !!omap - MAM01250x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02501x: -1 - MAM02503x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000088826 or ENSG00000148832" @@ -79853,8 +79861,8 @@ - MAM01831x: 1 - MAM01986x: 1 - MAM02040x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM02880x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -80301,9 +80309,9 @@ - MAM02007x: 1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000110887" @@ -81409,10 +81417,10 @@ - MAM01157x: 1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02426x: -1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "" @@ -81465,9 +81473,9 @@ - metabolites: !!omap - MAM00556x: 1 - MAM02039x: 1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02413x: -1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000179761" @@ -82719,26 +82727,6 @@ - subsystem: - "Phenylalanine, tyrosine and tryptophan biosynthesis" - confidence_score: 0 - - !!omap - - id: "MAR03940" - - name: "L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)" - - metabolites: !!omap - - MAM01698c: 1 - - MAM02040c: 1 - - MAM02630c: -1 - - MAM02724c: -1 - - MAM02978c: -1 - - MAM03101c: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000171759" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "1.14.16.1" - - references: "PMID:3298976;PMID:4074362" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" - - confidence_score: 0 - !!omap - id: "MAR04214" - name: "L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)" @@ -87326,9 +87314,9 @@ - MAM01638x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02819x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -87367,9 +87355,9 @@ - MAM01640x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000110887" @@ -87388,9 +87376,9 @@ - MAM01740x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02578x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000110887" @@ -94340,8 +94328,8 @@ - MAM02007x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM02661x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -94359,8 +94347,8 @@ - metabolites: !!omap - MAM01998x: -1 - MAM02007x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000101323 or ENSG00000116882" @@ -94874,8 +94862,8 @@ - name: "superoxide:superoxide oxidoreductase" - metabolites: !!omap - MAM02039x: -2 - - MAM02041x: 1 - - MAM02630x: 1 + - MAM01803x: 1 + - MAM01802x: 1 - MAM02631x: -2 - lower_bound: 0 - upper_bound: 1000 @@ -101137,8 +101125,8 @@ - metabolites: !!omap - MAM00113x: -1 - MAM01664x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -102508,8 +102496,8 @@ - name: "" - metabolites: !!omap - MAM00110x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03028x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -103070,8 +103058,8 @@ - metabolites: !!omap - MAM00682x: 1 - MAM01364x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -103175,8 +103163,8 @@ - metabolites: !!omap - MAM00073x: 1 - MAM01934x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -103247,8 +103235,8 @@ - metabolites: !!omap - MAM00072x: 1 - MAM00091x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -104599,8 +104587,8 @@ - metabolites: !!omap - MAM00380x: -1 - MAM01058x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000012779" @@ -106790,8 +106778,8 @@ - metabolites: !!omap - MAM01119x: 1 - MAM01120x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -107258,8 +107246,8 @@ - metabolites: !!omap - MAM01121x: 1 - MAM01122x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -107859,8 +107847,8 @@ - metabolites: !!omap - MAM00026x: 1 - MAM00582x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -108121,8 +108109,8 @@ - metabolites: !!omap - MAM00258x: -1 - MAM01037x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -108438,8 +108426,8 @@ - metabolites: !!omap - MAM00027x: 1 - MAM00587x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -108528,8 +108516,8 @@ - name: "" - metabolites: !!omap - MAM00423x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM02650x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -108657,8 +108645,8 @@ - metabolites: !!omap - MAM00015x: 1 - MAM02039x: -3 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM02652x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -116151,10 +116139,10 @@ - MAM01597x: -11 - MAM02039x: 11 - MAM02040x: -11 - - MAM02041x: 7 + - MAM01803x: 7 - MAM02552x: -11 - MAM02553x: 11 - - MAM02630x: -7 + - MAM01802x: -7 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "" @@ -116174,10 +116162,10 @@ - MAM01597x: -11 - MAM02039x: 11 - MAM02040x: -11 - - MAM02041x: 6 + - MAM01803x: 6 - MAM02552x: -11 - MAM02553x: 11 - - MAM02630x: -6 + - MAM01802x: -6 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "" @@ -116197,10 +116185,10 @@ - MAM01597x: -11 - MAM02039x: 3 - MAM02040x: -11 - - MAM02041x: 11 + - MAM01803x: 11 - MAM02552x: -11 - MAM02553x: 11 - - MAM02630x: -11 + - MAM01802x: -11 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "" @@ -116216,9 +116204,9 @@ - name: "" - metabolites: !!omap - MAM00049x: 1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02110x: -1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -116288,8 +116276,8 @@ - name: "" - metabolites: !!omap - MAM00064x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM02971x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -116361,8 +116349,8 @@ - metabolites: !!omap - MAM00040x: 1 - MAM01725x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -116433,8 +116421,8 @@ - metabolites: !!omap - MAM00043x: 1 - MAM01773x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -116504,8 +116492,8 @@ - name: "" - metabolites: !!omap - MAM00057x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM02941x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -116576,8 +116564,8 @@ - name: "" - metabolites: !!omap - MAM00051x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM02678x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -116648,9 +116636,9 @@ - name: "" - metabolites: !!omap - MAM00066x: 1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02495x: -1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -116720,9 +116708,9 @@ - name: "" - metabolites: !!omap - MAM00042x: 1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02345x: -1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -116793,8 +116781,8 @@ - metabolites: !!omap - MAM00039x: 1 - MAM01650x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -116864,8 +116852,8 @@ - name: "" - metabolites: !!omap - MAM00059x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM02644x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -116936,9 +116924,9 @@ - name: "" - metabolites: !!omap - MAM00053x: 1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02122x: -1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -117009,8 +116997,8 @@ - metabolites: !!omap - MAM01412x: -1 - MAM01622x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -117081,10 +117069,10 @@ - MAM01597x: -10 - MAM02039x: 10 - MAM02040x: -10 - - MAM02041x: 10 + - MAM01803x: 10 - MAM02552x: -10 - MAM02553x: 10 - - MAM02630x: -10 + - MAM01802x: -10 - MAM02774x: 1 - MAM03047x: -1 - lower_bound: 0 @@ -117101,9 +117089,9 @@ - id: "MAR03326" - name: "" - metabolites: !!omap - - MAM02041x: 1 + - MAM01803x: 1 - MAM02112x: -1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03016x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -117174,8 +117162,8 @@ - name: "" - metabolites: !!omap - MAM00025x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03015x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -117246,8 +117234,8 @@ - name: "" - metabolites: !!omap - MAM00016x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03013x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -117318,8 +117306,8 @@ - name: "" - metabolites: !!omap - MAM00007x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03012x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -117389,8 +117377,8 @@ - id: "MAR03342" - name: "" - metabolites: !!omap - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM02647x: -1 - MAM03025x: 1 - lower_bound: 0 @@ -117462,8 +117450,8 @@ - name: "" - metabolites: !!omap - MAM01191x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03019x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -117534,8 +117522,8 @@ - name: "" - metabolites: !!omap - MAM01141x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03022x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -117617,24 +117605,6 @@ - subsystem: - "Beta oxidation of unsaturated fatty acids (n-9) (peroxisomal)" - confidence_score: 0 - - !!omap - - id: "MAR03364" - - name: "" - - metabolites: !!omap - - MAM02041x: 1 - - MAM02630x: -1 - - MAM02677x: -1 - - MAM03020x: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "1.3.3.6" - - references: "PMID:1047780;PMID:8973539;PMID:11135616" - - subsystem: - - "Beta oxidation of unsaturated fatty acids (n-9) (peroxisomal)" - - confidence_score: 0 - !!omap - id: "MAR03365" - name: "" @@ -117689,24 +117659,6 @@ - subsystem: - "Beta oxidation of unsaturated fatty acids (n-9) (peroxisomal)" - confidence_score: 0 - - !!omap - - id: "MAR03369" - - name: "" - - metabolites: !!omap - - MAM00118x: -1 - - MAM02041x: 1 - - MAM02630x: -1 - - MAM03023x: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "1.3.3.6" - - references: "PMID:1047780;PMID:8973539;PMID:11135616" - - subsystem: - - "Beta oxidation of unsaturated fatty acids (n-9) (peroxisomal)" - - confidence_score: 0 - !!omap - id: "MAR03370" - name: "" @@ -117927,8 +117879,8 @@ - name: "" - metabolites: !!omap - MAM00078x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03027x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -118000,8 +117952,8 @@ - metabolites: !!omap - MAM00090x: 1 - MAM00948x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -118088,8 +118040,8 @@ - metabolites: !!omap - MAM00079x: 1 - MAM00080x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" @@ -118170,24 +118122,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR03301" - - name: "" - - metabolites: !!omap - - MAM02041x: 1 - - MAM02391x: -1 - - MAM02630x: -1 - - MAM03010x: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "1.3.3.6" - - references: "PMID:8973539;PMID:10407780;PMID:11356167" - - subsystem: - - "Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal)" - - confidence_score: 0 - !!omap - id: "MAR03302" - name: "" @@ -118242,24 +118176,6 @@ - subsystem: - "Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal)" - confidence_score: 0 - - !!omap - - id: "MAR03306" - - name: "" - - metabolites: !!omap - - MAM01577x: -1 - - MAM02041x: 1 - - MAM02630x: -1 - - MAM03009x: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "1.3.3.6" - - references: "PMID:8973539;PMID:10407780;PMID:11356167" - - subsystem: - - "Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal)" - - confidence_score: 0 - !!omap - id: "MAR03307" - name: "" @@ -118314,24 +118230,6 @@ - subsystem: - "Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal)" - confidence_score: 0 - - !!omap - - id: "MAR03311" - - name: "" - - metabolites: !!omap - - MAM01576x: -1 - - MAM02041x: 1 - - MAM02630x: -1 - - MAM03030x: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "1.3.3.6" - - references: "PMID:8973539;PMID:10407780;PMID:11356167" - - subsystem: - - "Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal)" - - confidence_score: 0 - !!omap - id: "MAR03312" - name: "" @@ -120690,8 +120588,8 @@ - name: "" - metabolites: !!omap - MAM00018x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03014x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -120762,8 +120660,8 @@ - name: "" - metabolites: !!omap - MAM01586x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03024x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -144957,25 +144855,7 @@ - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "1.3.3.6;1.17.99.-" - - references: "PMID:10709654" - - subsystem: - - "Bile acid biosynthesis" - - confidence_score: 0 - - !!omap - - id: "MAR01639" - - name: "" - - metabolites: !!omap - - MAM00618x: -1 - - MAM00749x: 1 - - MAM02041x: 1 - - MAM02630x: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "1.3.3.6;1.17.99.-" - - references: "PMID:11356170;PMID:8943006;PMID:10709654" + - references: "PMID:11356170;PMID:8943006" - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 @@ -145587,8 +145467,8 @@ - metabolites: !!omap - MAM00617x: -1 - MAM00755x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000168306" @@ -145608,11 +145488,11 @@ - MAM02040x: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000060971 and ENSG00000113790 and ENSG00000133835" + - gene_reaction_rule: "ENSG00000113790 or ENSG00000133835" - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "4.2.1.107" - - references: "PMID:8902629" + - references: "PMID:8902629;PMID:19357427" - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 @@ -161742,8 +161622,8 @@ - name: "hydrogen-peroxide:hydrogen-peroxide oxidoreductase" - metabolites: !!omap - MAM02040x: 2 - - MAM02041x: -2 - - MAM02630x: 1 + - MAM01803x: -2 + - MAM01802x: 1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000121691 or ENSG00000166016" @@ -201356,17 +201236,17 @@ - id: "MAR03473" - name: "" - metabolites: !!omap + - MAM01285c: -1 + - MAM01285x: 1 - MAM01334c: 1 - MAM01334x: -1 - - MAM01371c: -1 - - MAM01371x: 1 - - lower_bound: 0 + - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000100372" - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "" - - references: "PMID:16756494;PMID:9874197;PMID:12445829;PMID:14598172;PMID:18406340;PMID:9759482" + - references: "PMID:12445829;PMID:16756494;PMID:22185573" - subsystem: - "Transport reactions" - confidence_score: 0 @@ -201580,22 +201460,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR04915" - - name: "" - - metabolites: !!omap - - MAM01597c: -1 - - MAM01597x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "PMID:14598172" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR04924" - name: "" @@ -201922,38 +201786,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR07771" - - name: "" - - metabolites: !!omap - - MAM02552c: 1 - - MAM02552x: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07775" - - name: "" - - metabolites: !!omap - - MAM02553c: -1 - - MAM02553x: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR07777" - name: "" @@ -201986,86 +201818,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR07782" - - name: "" - - metabolites: !!omap - - MAM01285c: -1 - - MAM01285x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07783" - - name: "" - - metabolites: !!omap - - MAM01334c: -1 - - MAM01334x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07785" - - name: "" - - metabolites: !!omap - - MAM01371c: -1 - - MAM01371x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07788" - - name: "" - - metabolites: !!omap - - MAM01803c: -1 - - MAM01803x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07790" - - name: "" - - metabolites: !!omap - - MAM01802c: -1 - - MAM01802x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR07797" - name: "" @@ -218559,25 +218311,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR00059" - - name: "Acyl-Coenzyme A Oxidase 2, Branched Chain" - - metabolites: !!omap - - MAM00037x: 1 - - MAM00755x: -1 - - MAM01802x: 1 - - MAM01803x: -1 - - MAM02630x: -0.5 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000168306" - - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "1.3.3.6" - - references: "PMID:11181649" - - subsystem: - - "Bile acid biosynthesis" - - confidence_score: 0 - !!omap - id: "MAR00060" - name: "O-Acetylcarnintine Transport into Mitochondria via Diffusion" @@ -220621,8 +220354,8 @@ - MAM00558x: 1 - MAM01742x: -1 - MAM02039x: 1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000110887" @@ -222130,10 +221863,10 @@ - MAM01597x: -4 - MAM02039x: 4 - MAM02040x: -4 - - MAM02041x: 4 + - MAM01803x: 4 - MAM02552x: -4 - MAM02553x: 4 - - MAM02630x: -4 + - MAM01802x: -4 - MAM02644x: 1 - MAM02678x: -1 - lower_bound: 0 @@ -222250,10 +221983,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02678x: 1 - MAM02941x: -1 - lower_bound: 0 @@ -222443,10 +222176,10 @@ - MAM01934x: -1 - MAM02039x: 5 - MAM02040x: -5 - - MAM02041x: 2 + - MAM01803x: 2 - MAM02552x: -5 - MAM02553x: 5 - - MAM02630x: -2 + - MAM01802x: -2 - MAM02644x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -222491,10 +222224,10 @@ - MAM01597x: -5 - MAM02039x: 5 - MAM02040x: -5 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -5 - MAM02553x: 5 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02644x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -222539,10 +222272,10 @@ - MAM01773x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02941x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -222703,10 +222436,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "(ENSG00000060971 and ENSG00000133835 and ENSG00000161533) or (ENSG00000060971 and ENSG00000113790 and ENSG00000161533)" @@ -222751,10 +222484,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "(ENSG00000060971 and ENSG00000133835 and ENSG00000161533) or (ENSG00000060971 and ENSG00000113790 and ENSG00000161533)" @@ -222818,10 +222551,10 @@ - MAM01773x: 1 - MAM02039x: 2 - MAM02040x: -2 - - MAM02041x: 2 + - MAM01803x: 2 - MAM02552x: -2 - MAM02553x: 2 - - MAM02630x: -2 + - MAM01802x: -2 - MAM02971x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -222842,10 +222575,10 @@ - MAM01597x: -3 - MAM02039x: 3 - MAM02040x: -3 - - MAM02041x: 3 + - MAM01803x: 3 - MAM02552x: -3 - MAM02553x: 3 - - MAM02630x: -3 + - MAM01802x: -3 - MAM02647x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -222867,10 +222600,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "(ENSG00000060971 and ENSG00000133835 and ENSG00000161533) or (ENSG00000060971 and ENSG00000113790 and ENSG00000161533)" @@ -222891,10 +222624,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "(ENSG00000060971 and ENSG00000133835 and ENSG00000161533) or (ENSG00000060971 and ENSG00000113790 and ENSG00000161533)" @@ -222915,10 +222648,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "(ENSG00000060971 and ENSG00000133835 and ENSG00000161533) or (ENSG00000060971 and ENSG00000113790 and ENSG00000161533)" @@ -222939,10 +222672,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "(ENSG00000060971 and ENSG00000133835 and ENSG00000161533) or (ENSG00000060971 and ENSG00000113790 and ENSG00000161533)" @@ -222961,11 +222694,11 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02110x: -1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02971x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -223171,7 +222904,6 @@ - eccodes: "4.99.1.1" - references: "PMID:7983009;PMID:11175906;PMID:11215517;PMID:11853551;PMID:11947230;PMID:1624416;PMID:182145;PMID:2310748;PMID:3196293;PMID:3702737;PMID:406931;PMID:6425295;PMID:7309736;PMID:8818224;PMID:9712849;PMID:9808757" - subsystem: - - "Heme synthesis" - "Porphyrin metabolism" - confidence_score: 0 - !!omap @@ -225393,10 +225125,10 @@ - MAM01597x: -3 - MAM02039x: 5 - MAM02040x: -3 - - MAM02041x: 2 + - MAM01803x: 2 - MAM02552x: -3 - MAM02553x: 3 - - MAM02630x: -2 + - MAM01802x: -2 - MAM02774x: 2 - MAM03554x: 1 - MAM03887x: -1 @@ -225710,7 +225442,7 @@ - eccodes: "1.3.3.4" - references: "PMID:8771201" - subsystem: - - "Heme synthesis" + - "Porphyrin metabolism" - confidence_score: 0 - !!omap - id: "MAR01645" @@ -230717,11 +230449,11 @@ - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "1.3.99.13" + - rxnFrom: "Recon3D;HMRdatabase" + - eccodes: "1.3.99.13;1.3.3.6" - references: "PMID:10407780;PMID:11356167;PMID:8973539" - subsystem: - - "Fatty acid oxidation" + - "Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal)" - confidence_score: 0 - !!omap - id: "MAR02808" @@ -230735,11 +230467,11 @@ - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "1.3.99.13" + - rxnFrom: "Recon3D;HMRdatabase" + - eccodes: "1.3.99.13;1.3.3.6" - references: "PMID:10407780;PMID:11356167;PMID:8973539" - subsystem: - - "Fatty acid oxidation" + - "Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal)" - confidence_score: 0 - !!omap - id: "MAR02810" @@ -230753,11 +230485,11 @@ - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "1.3.99.13" + - rxnFrom: "Recon3D;HMRdatabase" + - eccodes: "1.3.99.13;1.3.3.6" - references: "PMID:10407780;PMID:11356167;PMID:8973539" - subsystem: - - "Fatty acid oxidation" + - "Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal)" - confidence_score: 0 - !!omap - id: "MAR02818" @@ -230773,7 +230505,7 @@ - rxnNotes: "" - rxnFrom: "Recon3D" - eccodes: "1.3.99.13" - - references: "PMID:10407780;PMID:11356167;PMID:8973539" + - references: "PMID:10407780;PMID:11356167;PMID:8973539;PMID:18536048;PMID:17458872" - subsystem: - "Fatty acid oxidation" - confidence_score: 0 @@ -232725,11 +232457,11 @@ - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "1.3.99.3" + - rxnFrom: "Recon3D;HMRdatabase" + - eccodes: "1.3.99.3;1.3.3.6" - references: "PMID:1047780;PMID:11135616;PMID:8973539" - subsystem: - - "Fatty acid oxidation" + - "Beta oxidation of unsaturated fatty acids (n-9) (peroxisomal)" - confidence_score: 0 - !!omap - id: "MAR03289" @@ -232743,11 +232475,11 @@ - upper_bound: 1000 - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "1.3.99.3" + - rxnFrom: "Recon3D;HMRdatabase" + - eccodes: "1.3.99.3;1.3.3.6" - references: "PMID:1047780;PMID:11135616;PMID:8973539" - subsystem: - - "Fatty acid oxidation" + - "Beta oxidation of unsaturated fatty acids (n-9) (peroxisomal)" - confidence_score: 0 - !!omap - id: "MAR03291" @@ -236249,8 +235981,8 @@ - id: "MAR04001" - name: "Acyl Coenzyme A Oxidase" - metabolites: !!omap - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03021x: 1 - MAM03352x: -1 - lower_bound: 0 @@ -239738,24 +239470,6 @@ - subsystem: - "Exchange/demand reactions" - confidence_score: 0 - - !!omap - - id: "MAR04966" - - name: "Fatty Acid Beta Oxidation (C10:1->C10:2), Peroxisomal" - - metabolites: !!omap - - MAM00678x: 1 - - MAM00980x: -1 - - MAM02041x: 1 - - MAM02630x: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000161533" - - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "" - - references: "PMID:18536048;PMID:17458872" - - subsystem: - - "Fatty acid oxidation" - - confidence_score: 0 - !!omap - id: "MAR04967" - name: "Fatty Acid Beta Oxidation (C10:1->C8), Mitochondrial" @@ -239860,8 +239574,8 @@ - id: "MAR04981" - name: "Fatty Acid Beta Oxidation (C10:2->C10:3), Peroxisomal" - metabolites: !!omap - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03542x: -1 - MAM03545x: 1 - lower_bound: 0 @@ -240040,10 +239754,10 @@ - MAM01650x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02644x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -240063,10 +239777,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03922x: 1 - MAM03924x: -1 - lower_bound: 0 @@ -240086,10 +239800,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02774x: 1 - MAM03554x: 1 - MAM04004x: -1 @@ -240336,11 +240050,11 @@ - MAM01650x: 1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02345x: -1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000060971 and ENSG00000113790 and ENSG00000133835 and ENSG00000161533" @@ -240378,10 +240092,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03491x: -1 - MAM03924x: 1 - lower_bound: 0 @@ -240455,10 +240169,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM04004x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -240528,10 +240242,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000060971 and ENSG00000113790 and ENSG00000133835 and ENSG00000161533" @@ -240593,10 +240307,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03203x: 1 - MAM03978x: -1 - lower_bound: 0 @@ -240660,10 +240374,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03211x: 1 - MAM03288x: -1 - lower_bound: 0 @@ -240708,12 +240422,12 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02345x: 1 - MAM02495x: -1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000060971 and ENSG00000113790 and ENSG00000133835 and ENSG00000161533" @@ -240751,10 +240465,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03491x: 1 - MAM03492x: -1 - lower_bound: 0 @@ -240795,10 +240509,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02774x: 1 - MAM03887x: -1 - lower_bound: 0 @@ -240911,10 +240625,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000060971 and ENSG00000113790 and ENSG00000133835 and ENSG00000161533" @@ -241055,8 +240769,8 @@ - id: "MAR05196" - name: "Fatty Acid Beta Oxidation (C16:3->C16:4), Peroxisomal" - metabolites: !!omap - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03274x: -1 - MAM03653x: 1 - lower_bound: 0 @@ -241208,8 +240922,8 @@ - id: "MAR05300" - name: "Fatty Acid Beta Oxidation (C16:4->C16:5), Peroxisomal" - metabolites: !!omap - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03273x: -1 - MAM03656x: 1 - lower_bound: 0 @@ -241343,11 +241057,11 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02495x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02678x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -241386,10 +241100,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03492x: 1 - MAM03655x: -1 - lower_bound: 0 @@ -241500,10 +241214,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03789x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -241702,10 +241416,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03273x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -241814,10 +241528,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03567x: -1 - MAM03789x: 1 - lower_bound: 0 @@ -241858,8 +241572,8 @@ - id: "MAR05374" - name: "Fatty Acid Beta Oxidation (C20:4->C20:5), Peroxisomal" - metabolites: !!omap - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03570x: 1 - MAM03571x: -1 - lower_bound: 0 @@ -241926,10 +241640,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03555x: -1 - MAM03567x: 1 - lower_bound: 0 @@ -242009,8 +241723,8 @@ - name: "Fatty Acid Beta Oxidation (C22:5->C22:6), Peroxisomal" - metabolites: !!omap - MAM00093x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03557x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -242177,10 +241891,10 @@ - MAM01773x: 1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000060971 and ENSG00000113790 and ENSG00000133835 and ENSG00000161533" @@ -242241,10 +241955,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03555x: 1 - lower_bound: 0 - upper_bound: 1000 @@ -242265,10 +241979,10 @@ - MAM01725x: 1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02971x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -242508,11 +242222,11 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02122x: -1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "ENSG00000060971 and ENSG00000113790 and ENSG00000133835 and ENSG00000161533" @@ -242531,10 +242245,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02944x: 1 - MAM03409x: -1 - lower_bound: 0 @@ -242603,10 +242317,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03659x: 1 - MAM03794x: -1 - lower_bound: 0 @@ -242651,11 +242365,11 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02122x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM02644x: -1 - lower_bound: 0 - upper_bound: 1000 @@ -242675,10 +242389,10 @@ - MAM01597x: -1 - MAM02039x: 1 - MAM02040x: -1 - - MAM02041x: 1 + - MAM01803x: 1 - MAM02552x: -1 - MAM02553x: 1 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03409x: 1 - MAM03922x: -1 - lower_bound: 0 @@ -270335,7 +270049,7 @@ - eccodes: "" - references: "PMID:21749716" - subsystem: - - "Heme synthesis" + - "Porphyrin metabolism" - confidence_score: 0 - !!omap - id: "MAR11317" @@ -271817,7 +271531,7 @@ - eccodes: "" - references: "PMID:21749716" - subsystem: - - "Heme synthesis" + - "Porphyrin metabolism" - confidence_score: 0 - !!omap - id: "MAR11407" @@ -273837,8 +273551,8 @@ - name: "Formation of 3-Hydroxy-Adipoyl Coa" - metabolites: !!omap - MAM02040x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03213x: 1 - MAM03409x: -1 - lower_bound: 0 @@ -273922,8 +273636,8 @@ - name: "Formation of 3-Hydroxy-Sebacoyl Coa" - metabolites: !!omap - MAM02040x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03259x: 1 - MAM03924x: -1 - lower_bound: 0 @@ -274007,8 +273721,8 @@ - name: "Formation of 3-Hydoxy-Suberyl Coa" - metabolites: !!omap - MAM02040x: -1 - - MAM02041x: 1 - - MAM02630x: -1 + - MAM01803x: 1 + - MAM01802x: -1 - MAM03261x: 1 - MAM03922x: -1 - lower_bound: 0 @@ -288173,10 +287887,10 @@ - MAM01597x: -2 - MAM02039x: 2 - MAM02040x: -2 - - MAM02041x: 2 + - MAM01803x: 2 - MAM02552x: -2 - MAM02553x: 2 - - MAM02630x: -1 + - MAM01802x: -1 - MAM03236x: -1 - MAM03238x: 1 - lower_bound: 0 @@ -295854,12 +295568,12 @@ - MAM01597x: -4 - MAM02039x: 3 - MAM02040x: -2 - - MAM02041x: 2 + - MAM01803x: 2 - MAM02552x: -4 - MAM02553x: 4 - MAM02554x: 1 - MAM02555x: -1 - - MAM02630x: -2 + - MAM01802x: -2 - MAM03580x: -1 - MAM03893x: 1 - lower_bound: 0 @@ -304878,7 +304592,7 @@ - confidence_score: 0 - !!omap - id: "MAR20113" - - name: "MAR20114" + - name: "MAR20113" - metabolites: !!omap - MAM00185c: -1 - MAM00185m: 1 @@ -304892,6 +304606,327 @@ - subsystem: - "Transport reactions" - confidence_score: 0 + - !!omap + - id: "MAR20114" + - name: "MAR20014" + - metabolites: !!omap + - MAM01802x: 1 + - MAM01803x: -1 + - MAM02630x: -1 + - MAM02041x: 1 + - lower_bound: 0 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000161533 or ENSG00000168306 or ENSG00000087008 or ENSG00000110887 or ENSG00000203797 or ENSG00000007171 or ENSG00000148832 or ENSG00000179761 or ENSG00000158125" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:30378035" + - subsystem: + - "Miscellaneous" + - confidence_score: 0 + - !!omap + - id: "MAR20115" + - name: "MAR20115" + - metabolites: !!omap + - MAM01334c: -1 + - MAM01334x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20116" + - name: "MAR20116" + - metabolites: !!omap + - MAM01285c: -1 + - MAM01285x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20117" + - name: "MAR20117" + - metabolites: !!omap + - MAM01334x: 1 + - MAM01802x: -1 + - MAM01828x: 1 + - MAM02039x: 2 + - MAM02040x: -1 + - lower_bound: 0 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000112874" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Riboflavin metabolism" + - confidence_score: 0 + - !!omap + - id: "MAR20118" + - name: "MAR20118" + - metabolites: !!omap + - MAM01597c: 1 + - MAM01597x: -1 + - MAM01828c: -1 + - MAM01828x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20119" + - name: "MAR20119" + - metabolites: !!omap + - MAM01802c: 1 + - MAM01802x: -1 + - MAM01828c: -1 + - MAM01828x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20120" + - name: "MAR20120" + - metabolites: !!omap + - MAM01828c: -1 + - MAM01828x: 1 + - MAM02552c: 1 + - MAM02552x: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20121" + - name: "MAR20121" + - metabolites: !!omap + - MAM01334c: 1 + - MAM01334x: -1 + - MAM01828c: -1 + - MAM01828x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20122" + - name: "MAR20122" + - metabolites: !!omap + - MAM01285c: 1 + - MAM01285x: -1 + - MAM01828c: -1 + - MAM01828x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20123" + - name: "MAR20123" + - metabolites: !!omap + - MAM01597c: 1 + - MAM01597x: -1 + - MAM01802c: -1 + - MAM01802x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20124" + - name: "MAR20124" + - metabolites: !!omap + - MAM01802c: -1 + - MAM01802x: 1 + - MAM02552c: 1 + - MAM02552x: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20125" + - name: "MAR20125" + - metabolites: !!omap + - MAM01334c: 1 + - MAM01334x: -1 + - MAM01802c: -1 + - MAM01802x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20126" + - name: "MAR20126" + - metabolites: !!omap + - MAM01285c: 1 + - MAM01285x: -1 + - MAM01802c: -1 + - MAM01802x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20127" + - name: "MAR20127" + - metabolites: !!omap + - MAM01597c: 1 + - MAM01597x: -1 + - MAM02552c: -1 + - MAM02552x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20128" + - name: "MAR20128" + - metabolites: !!omap + - MAM01334c: 1 + - MAM01334x: -1 + - MAM02552c: -1 + - MAM02552x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20129" + - name: "MAR20129" + - metabolites: !!omap + - MAM01285c: 1 + - MAM01285x: -1 + - MAM02552c: -1 + - MAM02552x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20130" + - name: "MAR20130" + - metabolites: !!omap + - MAM01334c: -1 + - MAM01334x: 1 + - MAM01597c: 1 + - MAM01597x: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20131" + - name: "MAR20131" + - metabolites: !!omap + - MAM01285c: -1 + - MAM01285x: 1 + - MAM01597c: 1 + - MAM01597x: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "ENSG00000100372" + - rxnNotes: "" + - rxnFrom: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 - genes: - !!omap - id: "ENSG00000000419" diff --git a/model/metabolites.tsv b/model/metabolites.tsv index 8e1e6f82..0029214d 100644 --- a/model/metabolites.tsv +++ b/model/metabolites.tsv @@ -3118,6 +3118,7 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM01827l" "MAM01827" "" "C00393" "" "" "" "PROTEIN" "" "HC01852" "HC01852" "MNXM5157" "m01827l" "m01827l" "MAM01827e" "MAM01827" "" "C00393" "" "" "" "PROTEIN" "" "HC01852" "HC01852" "MNXM5157" "m01827s" "m01827s" "MAM01828c" "MAM01828" "fmn" "C00061" "HMDB0001520" "CHEBI:17621" "643976" "" "" "HC00064" "fmn" "MNXM119" "m01828c" "m01828c" +"MAM01828x" "MAM01828" "fmn" "C00061" "HMDB0001520" "CHEBI:17621" "643976" "" "" "" "" "MNXM119" "" "" "MAM01829g" "MAM01829" "fn2m2masn" "G00016" "" "CHEBI:32984" "" "" "" "" "fn2m2masn" "MNXM12419" "m01829g" "m01829g" "MAM01830c" "MAM01830" "fol" "C00504" "HMDB0000121" "CHEBI:27470" "6037" "" "" "HC00396" "fol" "MNXM617" "m01830c" "m01830c" "MAM01830m" "MAM01830" "fol" "C00504" "HMDB0000121" "CHEBI:27470" "6037" "" "" "HC00396" "fol" "MNXM617" "m01830m" "m01830m" diff --git a/model/reactions.tsv b/model/reactions.tsv index b86a9515..0ac385b6 100644 --- a/model/reactions.tsv +++ b/model/reactions.tsv @@ -803,7 +803,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR08088" "R04188" "3AIBTm" "" "" "" "3AIBTm" "MNXR108721;MNXR94851" "HMR_8088" "RCR11385" "" 0 "" "RHEA:13993" "HMR_8088" "MAR08787" "R00923" "MMCDm" "" "" "" "MMCDm" "MNXR101656" "HMR_8787" "RCR11386" "" 0 "" "RHEA:21396" "HMR_8787" "MAR03743" "" "" "RE2117M" "" "" "RE2117M" "MNXR103611" "HMR_3743" "RCR11387" "" 0 "" "" "HMR_3743" -"MAR03940" "R01795" "PHETHPTOX" "R01795C" "r0399" "" "r0399" "MNXR102632;MNXR107174" "HMR_3940" "RCR11388" "" 0 "" "RHEA:30787" "HMR_3940" "MAR04214" "R00678" "TRPO2" "R00678C" "r0169" "" "TRPO2" "MNXR104944" "HMR_4214" "RCR11389" "" 0 "" "RHEA:24536" "HMR_4214" "MAR04216" "R01958" "FKYNH" "R01958C" "r0454" "" "FKYNH" "MNXR99596" "HMR_4216" "RCR11390" "" 0 "" "" "HMR_4216" "MAR04218" "R03936" "LFORKYNHYD" "R03936C" "r0646" "" "LFORKYNHYD" "MNXR101060;MNXR108539" "HMR_4218" "RCR11391" "" 0 "" "" "HMR_4218" @@ -956,7 +955,7 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR06889" "" "" "RE3201C" "" "" "RE3201C" "MNXR103829" "HMR_6889" "RCR11479" "" 0 "" "" "HMR_6889" "MAR07628" "R00690" "" "" "" "" "HMR_7628" "MNXR106645" "HMR_7628" "RCR11480" "" 0 "" "RHEA:10712" "HMR_7628" "MAR07756" "R02540" "" "" "" "" "HMR_7756" "MNXR95813" "HMR_7756" "RCR11481" "" 0 "" "RHEA:64820" "HMR_7756" -"MAR08539" "R07211" "PHETHPTOX2" "" "" "" "PHETHPTOX2" "MNXR102633" "HMR_8539" "RCR11482" "" 0 "" "RHEA:20273" "HMR_8539" +"MAR08539" "R07211" "PHETHPTOX2" "" "" "" "PHETHPTOX2" "MNXR102633" "HMR_8539" "RCR11482" "" 0 "" "RHEA:20273" "HMR_8539;MAR03940" "MAR08794" "R02539" "PACCOAL" "" "" "" "PACCOAL" "MNXR102315" "HMR_8794" "RCR11483" "" 0 "" "RHEA:20956" "HMR_8794" "MAR08795" "R02576" "PHACCOAGLNAC" "" "" "" "PHACCOAGLNAC" "MNXR102611" "HMR_8795" "RCR11484" "" 0 "" "RHEA:21844" "HMR_8795" "MAR08796" "R05841" "" "" "" "" "HMR_8796" "MNXR102612" "HMR_8796" "RCR11485" "" 0 "RHEA:27851" "RHEA:27850" "HMR_8796" @@ -2582,11 +2581,9 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR03352" "" "" "" "" "" "HMR_3352" "" "HMR_3352" "RCR12573" "" 0 "" "" "HMR_3352" "MAR03353" "" "" "" "" "" "HMR_3353" "" "HMR_3353" "RCR12574" "" 0 "" "" "HMR_3353" "MAR03355" "R04100" "DCIm" "" "" "" "FAOXC121x" "MNXR97183" "HMR_3355" "RCR12575" "" 0 "RHEA:23719" "RHEA:23716" "HMR_3355" -"MAR03364" "" "" "RE2913X" "" "" "" "" "HMR_3364" "RCR12576" "" 0 "" "" "HMR_3364" "MAR03365" "" "" "RE2919X" "" "" "RE2919X" "" "HMR_3365" "RCR12577" "" 0 "" "" "HMR_3365" "MAR03367" "" "" "RE2908X" "" "" "RE2908X" "" "HMR_3367" "RCR12578" "" 0 "" "" "HMR_3367" "MAR03368" "" "" "RE2916X" "" "" "RE2916X" "" "HMR_3368" "RCR12579" "" 0 "" "" "HMR_3368" -"MAR03369" "" "" "RE2914X" "" "" "" "" "HMR_3369" "RCR12580" "" 0 "" "" "HMR_3369" "MAR03370" "" "" "RE2920X" "" "" "RE2920X" "" "HMR_3370" "RCR12581" "" 0 "" "" "HMR_3370" "MAR03372" "" "" "RE2909X" "" "" "RE2909X" "" "HMR_3372" "RCR12582" "" 0 "" "" "HMR_3372" "MAR03373" "" "" "RE2917X" "" "" "RE2917X" "" "HMR_3373" "RCR12583" "" 0 "" "" "HMR_3373" @@ -2613,15 +2610,12 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR03514" "" "" "RE3093X" "" "" "RE3093X" "" "HMR_3514" "RCR12604" "" 0 "" "" "HMR_3514" "MAR03515" "" "" "RE3090X" "" "" "RE3090X" "" "HMR_3515" "RCR12605" "" 0 "" "" "HMR_3515" "MAR03517" "" "SCP22x" "RT0781" "" "" "SCP22x" "MNXR104294" "HMR_3517" "RCR20504" "" 0 "" "" "HMR_3517;SCP22x;MAR01709" -"MAR03301" "" "" "RE1516X" "" "" "" "" "HMR_3301" "RCR12606" "" 0 "" "" "HMR_3301" "MAR03302" "" "" "RE1523X" "" "" "RE1523X" "" "HMR_3302" "RCR12607" "" 0 "" "" "HMR_3302" "MAR03304" "" "" "RE0512X" "" "" "RE0512X" "" "HMR_3304" "RCR12608" "" 0 "" "" "HMR_3304" "MAR03305" "" "" "RE1531X" "" "" "RE1531X" "" "HMR_3305" "RCR12609" "" 0 "" "" "HMR_3305" -"MAR03306" "" "" "RE1517X" "" "" "" "" "HMR_3306" "RCR12610" "" 0 "" "" "HMR_3306" "MAR03307" "" "" "RE1522X" "" "" "RE1522X" "" "HMR_3307" "RCR12611" "" 0 "" "" "HMR_3307" "MAR03309" "" "" "RE1525X" "" "" "RE1525X" "" "HMR_3309" "RCR12612" "" 0 "" "" "HMR_3309" "MAR03310" "" "" "RE1532X" "" "" "RE1532X" "" "HMR_3310" "RCR12613" "" 0 "" "" "HMR_3310" -"MAR03311" "" "" "RE1518X" "" "" "" "" "HMR_3311" "RCR14519" "" 0 "" "" "HMR_3311" "MAR03312" "" "" "RE1521X" "" "" "RE1521X" "" "HMR_3312" "RCR14520" "" 0 "" "" "HMR_3312" "MAR03314" "" "" "RE1526X" "" "" "RE1526X" "" "HMR_3314" "RCR12614" "" 0 "" "" "HMR_3314" "MAR03315" "" "" "RE1533X" "" "" "RE1533X" "" "HMR_3315" "RCR12615" "" 0 "" "" "HMR_3315" @@ -4034,13 +4028,12 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR01627" "R08733" "" "" "" "R-HSA-193401" "HMR_1627" "MNXR112239" "HMR_1627" "RCR10394" "" 0 "" "" "HMR_1627" "MAR01629" "" "" "" "" "R-HSA-192325" "HMR_1629;HMR_1630" "MNXR125295" "HMR_1629;HMR_1630" "RCR20233;RCR20511" "" 0 "" "" "HMR_1629" "MAR01631" "" "" "" "" "R-HSA-192325" "HMR_1631" "MNXR125295" "HMR_1631" "RCR20512" "" 0 "" "" "HMR_1631" -"MAR01632" "R08734" "" "RE2624X" "" "R-HSA-192056" "AMACRp;RE2624X;HMR_1635;RE2624M" "MNXR112240" "HMR_1632;HMR_1635" "RCR10915;RCR13606" "" 0 "RHEA:40456" "RHEA:40455" "HMR_1632" -"MAR01638" "" "ACOX2x" "RE3247M" "r0706" "R-HSA-192335" "ACOX2x;HMR_1637;RE3247M" "MNXR105369;MNXR124225" "HMR_1638;HMR_1637" "RCR10916;RCR13607" "" 0 "" "" "HMR_1638" -"MAR01639" "" "" "RE3247X;RE3247M" "r0706" "R-HSA-192335" "RE3247X;r0706;HMR_1637;RE3247M" "MNXR105369;MNXR124225" "HMR_1639;HMR_1637" "RCR10917;RCR13607" "" 0 "" "" "HMR_1639;HMR_1637;MAR01637" -"MAR01642" "R04813" "HSD17B4x" "RE3248M" "r0744" "R-HSA-192331" "r0744;HMR_1644;HSD17B4x" "MNXR105377;MNXR109137;MNXR115598;MNXR100720" "HMR_1642;HMR_1644" "RCR10918;RCR12830" "" 0 "" "RHEA:18933" "HMR_1642;HMR_1644;MAR01644;HSD17B4x;MAR01458" -"MAR01646" "R04812" "HSD17B4x" "RE3250M" "r0743" "" "r0743;HMR_1651;HSD17B4x" "MNXR105376;MNXR109136;MNXR100720" "HMR_1646;HMR_1651" "RCR13608;RCR12831" "" 0 "" "" "HMR_1646;HMR_1651;MAR01651;HSD17B4x;MAR01458" -"MAR01652" "R03719" "SCPx" "R03719X" "r0628" "" "SCPx;HMR_1653" "MNXR104297;MNXR108369" "HMR_1652;HMR_1653" "RCR13609;RCR13610" "" 0 "" "RHEA:16865" "HMR_1652;HMR_1653;MAR01653" -"MAR01659" "" "" "" "r2501;r0990" "" "r2501;r0990" "MNXR106313;MNXR105412" "HMR_1659;HMR_1656" "RCR20234;RCR20134" "3.A.1.203.3" 0 "" "" "HMR_1659;HMR_1565;MAR01656" +"MAR01632" "R08734" "" "RE2624X" "" "R-HSA-192056" "AMACRp;RE2624X" "MNXR112240" "HMR_1632" "RCR10915" "" 0 "RHEA:40456" "RHEA:40455" "HMR_1632" +"MAR01638" "" "ACOX2x" "RE3247X" "r0706" "R-HSA-192335" "ACOX2x;RE3247X;r0706" "MNXR105369;MNXR124225" "HMR_1638;HMR_1639" "RCR10916;RCR10917" "" 0 "" "" "HMR_1638;HMR_1639;MAR01639" +"MAR01642" "R04813" "" "" "r0744" "R-HSA-192331" "r0744" "MNXR105377;MNXR109137;MNXR115598" "HMR_1642" "RCR10918" "" 0 "" "RHEA:18933" "HMR_1642" +"MAR01646" "R04812" "" "" "r0743" "" "r0743" "MNXR105376;MNXR109136" "HMR_1646" "RCR13608" "" 0 "" "" "HMR_1646" +"MAR01652" "R03719" "SCPx" "R03719X" "r0628" "" "SCPx" "MNXR104297;MNXR108369" "HMR_1652" "RCR13609" "" 0 "" "RHEA:16865" "HMR_1652" +"MAR01659" "" "" "" "r2501" "" "r2501" "MNXR106313" "HMR_1659" "RCR20234" "3.A.1.203.3" 0 "" "" "HMR_1659" "MAR01660" "R07296" "" "RE1834C" "r0794" "" "RE1834C" "MNXR103558;MNXR110971" "HMR_1660" "RCR10217" "" 0 "RHEA:14542" "RHEA:14541" "HMR_1660" "MAR01663" "R07296" "" "RE1834X;RE1834M" "" "" "RE1834X;RE1834M" "MNXR103558;MNXR110971" "HMR_1663;HMR_1662" "RCR13612;RCR13611" "" 0 "RHEA:14542" "RHEA:14541" "HMR_1663;HMR_1662;MAR01662" "MAR01665" "" "" "" "" "R-HSA-193399" "HMR_1665;HMR_1666" "MNXR125298" "HMR_1665;HMR_1666" "RCR20513;RCR20514" "" 0 "RHEA:72683" "RHEA:72683" "HMR_1665;HMR_1666;MAR01666" @@ -4531,7 +4524,7 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR04834" "R05046" "" "R05046C" "r0776" "" "r0776" "MNXR105382" "HMR_4834" "RCR14690" "" 0 "" "" "HMR_4834" "MAR04835" "R05048" "" "R05048C" "r0777" "" "r0777" "MNXR105383" "HMR_4835" "RCR13860" "" 0 "" "" "HMR_4835" "MAR04836" "R05048" "" "R05048C" "r0778" "" "r0778" "MNXR105383" "HMR_4836" "RCR13861" "" 0 "" "" "HMR_4836" -"MAR08538" "R04734" "THBPT4ACAMDASE" "" "" "" "THBPT4ACAMDASE" "MNXR104802" "HMR_8538" "RCR10142" "" 0 "" "RHEA:11920" "HMR_8538" +"MAR08538" "R04734" "THBPT4ACAMDASE" "" "" "" "THBPT4ACAMDASE" "MNXR104802" "HMR_8538" "RCR10142" "" 0 "" "RHEA:11920" "HMR_8538;MAR03940" "MAR08738" "R04286" "PTHPSn" "" "" "" "PTHPSn" "MNXR103331" "HMR_8738" "RCR14691" "" 0 "" "RHEA:22048" "HMR_8738" "MAR08739" "R08208" "SPRn" "" "" "" "SPRn" "MNXR104500" "HMR_8739" "RCR14692" "" 0 "" "RHEA:32627" "HMR_8739" "MAR08740" "" "DIGALSGALSIDEtg" "" "" "" "DHPR2" "MNXR97459" "HMR_8740" "RCR13862" "" 0 "" "" "HMR_8740" @@ -7020,7 +7013,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR04890" "" "H2Otp" "" "r0852" "" "H2Otp" "MNXR98641" "HMR_4890" "RCR20016" "" 0 "RHEA:29670" "RHEA:29667" "HMR_4890" "MAR04900" "" "O2tp" "" "r0857" "" "O2tp" "MNXR102090" "HMR_4900" "RCR20059" "" 0 "" "" "HMR_4900" "MAR04908" "R00124" "r0860" "" "r0860" "" "r0860" "MNXR96123" "HMR_4908" "RCR20198" "" 0 "RHEA:35002" "RHEA:34999" "HMR_4908" -"MAR04915" "" "COAtp" "" "r0864" "" "COAtp" "MNXR96815" "HMR_4915" "RCR20004" "" 0 "" "" "HMR_4915" "MAR04924" "" "CO2tp" "" "r0869" "" "CO2tp" "MNXR96810" "HMR_4924" "RCR20149" "" 0 "" "" "HMR_4924" "MAR04930" "" "PYRt2p" "" "r0874" "" "PYRt2p" "MNXR103385" "HMR_4930" "RCR20123" "2.A.1.13.1;2.A.1.13.5" 0 "RHEA:64723" "RHEA:64720" "HMR_4930" "MAR04945" "" "" "RT0324" "" "" "FORMCOAtx" "" "HMR_4945" "RCR20306" "" 0 "" "" "HMR_4945" @@ -7041,15 +7033,8 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR07646" "" "DALAxt" "" "" "" "DALAxt" "MNXR95702" "HMR_7646" "RCR21081" "" 0 "" "" "HMR_7646" "MAR07705" "" "GLYCLTtp" "" "" "" "GLYCLTtp" "MNXR100333" "HMR_7705" "RCR20712" "" 0 "" "" "HMR_7705" "MAR07707" "" "GLXtp" "" "" "" "GLXtp" "MNXR100306" "HMR_7707" "RCR20200" "" 0 "" "" "HMR_7707" -"MAR07771" "" "NADtpu" "" "" "" "NADtx" "MNXR101881" "HMR_7771" "RCR20023" "" 0 "" "" "HMR_7771" -"MAR07775" "" "NADHtpu" "" "" "" "NADHtpu;NADtpu" "MNXR101881" "HMR_7775" "RCR20024" "" 0 "" "" "HMR_7775" "MAR07777" "" "NADPtxu" "" "" "" "NADPtxu" "MNXR101896" "HMR_7777" "RCR20713" "" 0 "" "" "HMR_7777" "MAR07779" "" "NADPHtxu" "" "" "" "NADPHtxu" "MNXR101894" "HMR_7779" "RCR20311" "" 0 "" "" "HMR_7779" -"MAR07782" "" "ADPtx" "" "" "" "ADPtx" "MNXR95484" "HMR_7782" "RCR20201" "" 0 "" "" "HMR_7782" -"MAR07783" "" "AMPtp" "" "" "" "AMPtp" "MNXR95830" "HMR_7783" "RCR20046" "" 0 "" "" "HMR_7783" -"MAR07785" "" "ATPtx" "" "" "" "ATPtx" "MNXR96140" "HMR_7785" "RCR20040" "" 0 "" "" "HMR_7785" -"MAR07788" "" "FADH2tx" "" "" "" "FADH2tx" "MNXR99212" "HMR_7788" "RCR20202" "" 0 "" "" "HMR_7788" -"MAR07790" "" "FADtx" "" "" "" "FADtx" "MNXR99217" "HMR_7790" "RCR20203" "" 0 "" "" "HMR_7790" "MAR07797" "" "AKGtp" "" "" "" "AKGtp" "MNXR95663" "HMR_7797" "RCR20150" "" 0 "" "" "HMR_7797" "MAR08016" "" "LYStip" "" "" "" "LYStip" "MNXR101269" "HMR_8016" "RCR20033" "" 0 "" "" "HMR_8016" "MAR08020" "" "THP2Ctp" "" "" "" "THP2Ctp" "MNXR104832" "HMR_8020" "RCR20714" "" 0 "" "" "HMR_8020" @@ -8081,7 +8066,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR00056" "" "ACACtx" "" "" "" "ACACtx" "MNXR95208" "" "" "" 0 "RHEA:29754" "RHEA:29751" "ACACtx" "MAR00057" "" "ACCOAtr" "" "" "" "ACCOAtr" "MNXR95223" "" "" "" 0 "" "" "ACCOAtr" "MAR00058" "" "ACHVESSEC" "" "" "" "ACHVESSEC" "MNXR95266" "" "" "" 0 "" "" "ACHVESSEC" -"MAR00059" "" "ACOX22x" "" "" "" "ACOX22x" "MNXR95389" "" "" "" 0 "" "" "ACOX22x" "MAR00060" "" "ACRNtm" "" "" "" "ACRNtm" "MNXR95412" "" "" "" 0 "" "" "ACRNtm" "MAR00061" "" "ACt2m" "" "" "" "ACt2m" "MNXR95429" "" "" "" 0 "" "" "ACt2m" "MAR00062" "" "ADPRDPm" "" "" "" "ADPRDPm" "MNXR95480" "" "" "" 0 "" "" "ADPRDPm" @@ -8748,10 +8732,10 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR02784" "" "RE1448N" "" "" "" "RE1448N" "MNXR103512" "" "" "" 0 "" "" "RE1448N" "MAR02786" "" "" "" "" "" "RE1514M" "" "" "" "" 0 "" "" "RE1514M" "MAR02802" "" "" "" "" "" "RE1514X" "" "" "" "" 0 "" "" "RE1514X" -"MAR02804" "" "RE1516X" "" "" "" "RE1516X" "" "" "" "" 0 "" "" "RE1516X" -"MAR02808" "" "RE1517X" "" "" "" "RE1517X" "" "" "" "" 0 "" "" "RE1517X" -"MAR02810" "" "RE1518X" "" "" "" "RE1518X" "" "" "" "" 0 "" "" "RE1518X" -"MAR02818" "" "RE1519X" "" "" "" "RE1519X" "" "" "" "" 0 "" "" "RE1519X" +"MAR02804" "" "RE1516X" "RE1516X" "" "" "RE1516X" "" "HMR_3301" "RCR12606" "" 0 "" "" "RE1516X;HMR_3301" +"MAR02808" "" "RE1517X" "RE1517X" "" "" "RE1517X" "" "HMR_3306" "RCR12610" "" 0 "" "" "RE1517X;HMR_3306;MAR00306" +"MAR02810" "" "RE1518X" "RE1518X" "" "" "RE1518X" "" "HMR_3311" "RCR14519" "" 0 "" "" "RE1518X;HMR_3311;MAR03311" +"MAR02818" "" "RE1519X;FAOXC101C102x" "" "" "" "RE1519X;FAOXC101C102x" "" "" "" "" 0 "" "" "RE1519X;FAOXC101C102x;MAR04966" "MAR02820" "" "RE1525C" "" "" "" "RE1525C" "MNXR103515" "" "" "" 0 "" "" "RE1525C" "MAR02826" "" "RE1526C" "" "" "" "RE1526C" "MNXR103516" "" "" "" 0 "" "" "RE1526C" "MAR02828" "" "RE1527C" "" "" "" "RE1527C" "MNXR103517" "" "" "" 0 "" "" "RE1527C" @@ -8854,8 +8838,8 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR03271" "" "" "" "" "" "RE2911C" "" "" "" "" 0 "" "" "RE2911C" "MAR03273" "" "RE2912M" "" "" "" "RE2912M" "" "" "" "" 0 "" "" "RE2912M" "MAR03274" "" "" "" "" "" "RE2912X" "" "" "" "" 0 "" "" "RE2912X" -"MAR03276" "" "" "" "" "" "RE2913X" "" "" "" "" 0 "" "" "RE2913X" -"MAR03289" "" "" "" "" "" "RE2914X" "" "" "" "" 0 "" "" "RE2914X" +"MAR03276" "" "" "RE2913X" "" "" "RE2913X" "" "HMR_3364" "RCR12576" "" 0 "" "" "RE2913X;HMR_3364;MAR03364" +"MAR03289" "" "" "RE2914X" "" "" "RE2914X" "" "HMR_3369" "RCR12580" "" 0 "" "" "RE2914X;HMR_3369;MAR03369" "MAR03291" "" "" "" "" "" "RE2915M" "" "" "" "" 0 "" "" "RE2915M" "MAR03295" "" "" "" "" "" "RE2915X" "" "" "" "" 0 "" "" "RE2915X" "MAR03297" "" "" "" "" "" "RE2921M" "" "" "" "" 0 "" "" "RE2921M" @@ -9080,7 +9064,7 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR04092" "" "EX_prostgh2_e" "" "" "" "EX_prostgh2[e]" "MNXR98873" "" "" "" 0 "" "" "EX_prostgh2[e]" "MAR04094" "" "EX_prostgi2_e" "" "" "" "EX_prostgi2[e]" "MNXR98874" "" "" "" 0 "" "" "EX_prostgi2[e]" "MAR04096" "" "EX_cdp_e" "" "" "" "EX_cdp[e]" "MNXR98331" "" "" "" 0 "" "" "EX_cdp[e]" -"MAR04098" "" "EX_dtdp_e" "" "" "" "EX_dtdp[e]" "MNXR98432" "" "" "" 0 "" "" "EX_dtdp[e]" +"MAR04098" "" "EX_dtdp_e" "" "" "" "EX_dtdp[e]" "MNXR98432" "" "" "" 0 "" "" "EX_dtdp[e];MAR07785" "MAR04100" "" "EX_HC00955_e" "" "" "" "EX_HC00955[e]" "MNXR98138" "" "" "" 0 "" "" "EX_HC00955[e]" "MAR04102" "" "" "" "" "" "EX_HC00002[e]" "" "" "" "" 0 "" "" "EX_HC00002[e]" "MAR04104" "" "" "" "" "" "EX_HC00003[e]" "" "" "" "" 0 "" "" "EX_HC00003[e]" @@ -9256,7 +9240,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR04943" "" "EX_ivcrn_e" "" "" "" "EX_ivcrn[e]" "MNXR98685" "" "" "" 0 "" "" "EX_ivcrn[e]" "MAR04950" "" "EX_tetdec2crn_e" "" "" "" "EX_tetdec2crn[e]" "" "" "" "" 0 "" "" "EX_tetdec2crn[e]" "MAR04965" "" "EX_tetdece1crn_e" "" "" "" "EX_tetdece1crn[e]" "" "" "" "" 0 "" "" "EX_tetdece1crn[e]" -"MAR04966" "" "FAOXC101C102x" "" "" "" "FAOXC101C102x" "" "" "" "" 0 "" "" "FAOXC101C102x" "MAR04967" "" "FAOXC101C8m" "" "" "" "FAOXC101C8m" "" "" "" "" 0 "" "" "FAOXC101C8m" "MAR04968" "" "FAOXC101C8x" "" "" "" "FAOXC101C8x" "" "" "" "" 0 "" "" "FAOXC101C8x" "MAR04970" "" "FAOXC102C101m" "" "" "" "FAOXC102C101m" "" "" "" "" 0 "" "" "FAOXC102C101m" @@ -12973,3 +12956,21 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR20111" "R00472" "" "" "" "" "" "MNXR188337" "" "" "" 0 "RHEA:18182" "RHEA:18181" "" "MAR20112" "R04385" "" "" "" "" "" "MNXR96330" "" "" "" 0 "" "RHEA:13501" "" "MAR20113" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20114" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20115" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20116" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20117" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20118" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20119" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20120" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20121" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20122" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20123" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20124" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20125" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20126" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20127" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20128" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20129" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20130" "" "" "" "" "" "" "" "" "" "" 0 "" "" "" +"MAR20131" "" "" "" "" "" "" "" "" "" "" 0 "" "" ""