diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml
index 5bd4eec7..dd78dd03 100644
--- a/model/Human-GEM.yml
+++ b/model/Human-GEM.yml
@@ -245011,13 +245011,13 @@
       - metabolites: !!omap
           - MAM01753c: -1
           - MAM01753m: 1
-      - lower_bound: 0
+      - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: ""
+      - gene_reaction_rule: "ENSG00000171612"
       - rxnNotes: ""
       - rxnFrom: "Recon3D"
       - eccodes: ""
-      - references: "PMID:16816105;PMID:17403938"
+      - references: "PMID:25320081"
       - subsystem:
           - "Transport reactions"
       - confidence_score: 0