diff --git a/code/addMetabolicNetwork.m b/code/addMetabolicNetwork.m index f5551bfa..2c2ed107 100644 --- a/code/addMetabolicNetwork.m +++ b/code/addMetabolicNetwork.m @@ -144,8 +144,11 @@ newGenes = setdiff(newGenes, newModel.genes); end -% append new genes to list of model genes +% append new genes and their names to model newModel.genes = [newModel.genes; newGenes]; +emptyGeneNames = newGenes; +emptyGeneNames(:) = {''}; +newModel.geneShortNames = [newModel.geneShortNames; emptyGeneNames]; % add new columns to rxnGeneMat will be updated after the new reactions are added below. newModel.rxnGeneMat(:, end+1:end+numel(newGenes)) = 0; diff --git a/code/test/sanityCheck.py b/code/test/sanityCheck.py index f1afed80..12e8d035 100644 --- a/code/test/sanityCheck.py +++ b/code/test/sanityCheck.py @@ -38,8 +38,12 @@ def checkRxnAnnotation(rxns): rxnList = get_column_from_tsv("model/reactions.tsv", "rxns") spontaneous = get_column_from_tsv("model/reactions.tsv", "spontaneous", False) rxnDeprecated = get_column_from_tsv("data/deprecatedIdentifiers/deprecatedReactions.tsv", "rxns") - assert set(rxnList).isdisjoint(set(rxnDeprecated)), "Deprecated reaction reused!" - assert rxnList == rxns, "Reaction annotation mismatch!" + rxnMisused = set(rxns).intersection(set(rxnDeprecated)) + assert len(rxnMisused) == 0, "Deprecated reaction(s) used: {}".format(rxnMisused) + rxnMisused = set(rxns).difference(set(rxnList)) + assert len(rxnMisused) == 0, "Reaction(s) not annotated in reactions.tsv: {}".format(rxnMisused) + rxnMisused = set(rxnList).difference(set(rxns)) + assert len(rxnMisused) == 0, "Annotated reactions are missing from the model: {}".format(rxnMisused) assert pd.api.types.is_numeric_dtype(spontaneous), "Spontaneous column should be in numeric!" @@ -49,16 +53,22 @@ def checkMetAnnotation(mets): """ metList = get_column_from_tsv("model/metabolites.tsv", "mets") metDeprecated = get_column_from_tsv("data/deprecatedIdentifiers/deprecatedMetabolites.tsv", "mets") - assert set(metList).isdisjoint(set(metDeprecated)), "Deprecated metabolite reused!" - assert metList == mets, "Metabolite annotation mismatch!" - + metMisused = set(mets).intersection(set(metDeprecated)) + assert len(metMisused) == 0, "Deprecated metabolite(s) used: {}".format(metMisused) + metMisused = set(mets).difference(set(metList)) + assert len(metMisused) == 0, "Metabolite(s) not annotated in metabolites.tsv: {}".format(metMisused) + metMisused = set(metList).difference(set(mets)) + assert len(metMisused) == 0, "Annotated metabolite(s) are missing from the model: {}".format(metMisused) def checkGeneAnnotation(genes): """ check consistency of gene lists between model and annotation file """ geneList = get_column_from_tsv("model/genes.tsv", "genes") - assert geneList == genes, "Gene annotation mismatch!" + geneMisused = set(genes).difference(set(geneList)) + assert len(geneMisused) == 0, "Gene(s) not annotated in genes.tsv: {}".format(geneMisused) + geneMisused = set(geneList).difference(set(genes)) + assert len(geneMisused) == 0, "Annotated gene(s) are missing from the model: {}".format(geneMisused) def find_unused_entities(model, entity_type): diff --git a/code/updateAnimalGEM.m b/code/updateAnimalGEM.m index f10633e3..5ce90e94 100644 --- a/code/updateAnimalGEM.m +++ b/code/updateAnimalGEM.m @@ -1,4 +1,4 @@ -function [animalGEM, speciesSpecNetwork, gapfillNetwork]=updateAnimalGEM(orthologPairs,rxnsToAdd,metsToAdd,modelId) +function [animalGEM, speciesSpecNetwork, gapfillNetwork]=updateAnimalGEM(orthologPairs,rxnsToAdd,metsToAdd,modelId,resetBiomass) % updateAnimalGEM % Generate a model by using the Human-GEM as a template and taking into % account species-specific pathways/reactions @@ -11,7 +11,9 @@ % rxnsToAdd the structure of species-specific reactions % metsToAdd the structure of species-specific metabolites % modelId model id -% +% resetBiomass reset biomass objective function to "biomass_components" +% which is constituted by generic componenets that +% suppose to occur in a eukaryotic cell (opt, default TRUE) % % Output: % animalGEM an updated animal GEM @@ -81,7 +83,8 @@ %% Gap-filling -[animalGEM, gapfillNetwork]=gapfill4EssentialTasks(animalGEM,ihuman); +[animalGEM, gapfillNetwork]=gapfill4EssentialTasks(animalGEM,ihuman,resetBiomass); +animalGEM.b = animalGEM.b(:,1); % ensure b field in single column %% post-gapfilling procedures diff --git a/data/deprecatedIdentifiers/deprecatedMetabolites.tsv b/data/deprecatedIdentifiers/deprecatedMetabolites.tsv index db6b5abb..09b77b2d 100644 --- a/data/deprecatedIdentifiers/deprecatedMetabolites.tsv +++ b/data/deprecatedIdentifiers/deprecatedMetabolites.tsv @@ -2228,5 +2228,23 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM03368m" "MAM03368" "" "C05467" "HMDB0006891" "CHEBI:27379" "440690" "" "CE5169" "" "CE5169" "" "" "CE5169_m" "MAM03368x" "MAM03368" "" "C05467" "HMDB0006891" "CHEBI:27379" "440690" "" "CE5169" "" "CE5169" "" "" "CE5169_p" "MAM00902c" "MAM00902" "" "" "" "" "" "" "CE4820" "" "CE4820" "MNXM164259" "m00902c" "m00902c" +"MAM00616m" "MAM00616" "cholcoar" "C15613" "" "CHEBI:37642" "15942889" "LMST01010218" "CE5165" "HC01348" "cholcoar" "MNXM549;MNXM90922;MNXM91096" "m00616p" "m00616p" +"MAM00749m" "MAM00749" "cholcoads" "C05460" "HMDB0006889" "CHEBI:27505" "5280797" "LMST01010217" "" "HC01466" "cholcoads" "MNXM162945;MNXM2747" "m00749m" "m00749m" +"MAM00036m" "MAM00036" "" "C05450" "" "CHEBI:52050" "46224537" "" "CE5168" "" "HC01459" "MNXM732;MNXM827" "m00036m" "m00036m" +"MAM00748m" "MAM00748" "cholcoaone" "C05467" "HMDB0006891" "CHEBI:27379" "440690" "LMST01010216" "CE5169" "HC01473" "cholcoaone" "MNXM162946;MNXM873" "m00748m" "m00748m" +"MAM03367m" "MAM03367" "" "" "" "" "" "" "CE5168" "" "CE5168" "" "" "CE5168_m" +"MAM00618m" "MAM00618" "cholcoas" "C17343" "" "CHEBI:37643" "15942888" "" "CE5166" "" "CE5166;cholcoas" "MNXM1201;MNXM8131" "m00618m" "m00618m" +"MAM01445m" "MAM01445" "cholate" "C00695" "HMDB0000619" "CHEBI:16359" "221493" "LMST04010001" "" "HC00502" "cholate" "MNXM450" "m01445m" "m01445m" +"MAM01514m" "MAM01514" "cholcoa" "C01794" "HMDB0001374" "CHEBI:15519" "439573" "" "" "HC00844" "cholcoa" "MNXM162468;MNXM431" "m01514m" "m01514m" "MAM00759c" "MAM00759" "" "C13712" "" "" "" "LMST02030130" "" "" "M00759" "MNXM3494" "m00759c" "m00759c" "MAM02397c" "MAM02397" "" "C16239" "" "" "" "" "" "" "M02397" "MNXM19093" "m02397c" "m02397c" +"MAM01268c" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268c" "m01268c" +"MAM01268m" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268m" "m01268m" +"MAM01268n" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268n" "m01268n" +"MAM01268x" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268p" "m01268p" +"MAM01268r" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268r" "m01268r" +"MAM01268e" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268s" "m01268s" +"MAM02757c" "MAM02757" "" "" "" "" "" "" "" "" "M02757" "" "m02757c" "m02757c" +"MAM02757l" "MAM02757" "" "" "" "" "" "" "" "" "M02757" "" "m02757l" "m02757l" +"MAM02757n" "MAM02757" "" "" "" "" "" "" "" "" "M02757" "" "m02757n" "m02757n" +"MAM01816n" "MAM01816" "" "" "" "" "" "PROTEIN" "" "" "M01816" "" "m01816n" "m01816n" diff --git a/data/deprecatedIdentifiers/deprecatedReactions.tsv b/data/deprecatedIdentifiers/deprecatedReactions.tsv index ebc76196..eddba6e4 100644 --- a/data/deprecatedIdentifiers/deprecatedReactions.tsv +++ b/data/deprecatedIdentifiers/deprecatedReactions.tsv @@ -194,7 +194,29 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR03441" "" "RE3150C" "" "" "" "RE3150C" "MNXR103806" "" "" "" 0 "" "" "RE3150C" "MAR10164" "" "" "" "" "" "CE2516t" "" "" "" "" 0 "" "" "CE2516t" "MAR10433" "" "" "" "" "" "EX_CE2516[e]" "" "" "" "" 0 "" "" "EX_CE2516[e]" +"MAR01630" "" "" "" "" "R-HSA-192325" "HMR_1630" "MNXR125295" "HMR_1630" "RCR20511" "" 0 "" "" "HMR_1630" +"MAR01635" "R08734" "" "RE2624M" "" "R-HSA-192056" "HMR_1635;RE2624M" "MNXR112240" "HMR_1635" "RCR13606" "" 0 "RHEA:40456" "RHEA:40455" "HMR_1635" +"MAR01637" "" "" "RE3247M" "r0706" "R-HSA-192335" "HMR_1637;RE3247M" "MNXR105369;MNXR124225" "HMR_1637" "RCR13607" "" 0 "" "" "HMR_1637" +"MAR01644" "R04813" "" "RE3248M" "" "" "HMR_1644" "" "HMR_1644" "RCR12830" "" 0 "" "RHEA:18933" "HMR_1644" +"MAR01653" "R03719" "SCPx" "R03719X" "r0628" "" "HMR_1653" "MNXR104297;MNXR108369" "HMR_1653" "RCR13610" "" 0 "" "RHEA:16865" "HMR_1653" +"MAR03754" "" "" "" "" "" "RE3248M" "" "" "" "" 0 "" "" "RE3248M" +"MAR03760" "" "" "" "" "" "RE3250M" "" "" "" "" 0 "" "" "RE3250M" +"MAR01656" "" "" "" "r0990" "" "r0990" "MNXR105412" "HMR_1656" "RCR20134" "" 0 "" "" "HMR_1656" +"MAR07758" "" "" "RT0402" "" "" "HMR_7758" "" "HMR_7758" "RCR20277" "" 0 "" "" "HMR_7758" +"MAR01662" "R07296" "" "RE1834M" "" "" "RE1834M" "MNXR103558;MNXR110971" "HMR_1662" "RCR13611" "" 0 "RHEA:14542" "RHEA:14541" "HMR_1662" +"MAR01666" "" "" "" "" "R-HSA-193399" "HMR_1666" "MNXR125298" "HMR_1666" "RCR20514" "" 0 "RHEA:72683" "RHEA:72683" "HMR_1666" +"MAR01458" "" "HSD17B4x" "" "" "" "HSD17B4x" "MNXR100720" "" "" "" 0 "" "" "HSD17B4x" +"MAR01651" "R04812" "" "RE3250M" "" "" "HMR_1651" "" "HMR_1651" "RCR12831" "" 0 "" "" "HMR_1651" "MAR09887" "" "GLNB0AT3tc" "" "" "" "GLNB0AT3tc" "" "" "" "" 0 "" "" "GLNB0AT3tc" +"MAR00024" "" "" "" "" "" "HMR_0024" "" "HMR_0024" "RCR13367" "" 0 "" "" "HMR_0024" +"MAR00025" "" "" "" "" "" "HMR_0025;HMR_0030" "" "HMR_0025;HMR_0030" "RCR20226;RCR20227" "" 0 "" "" "HMR_0025;HMR_0030;MAR00030" +"MAR00026" "" "" "" "" "" "HMR_0026" "" "HMR_0026" "RCR21051" "" 0 "" "" "HMR_0026" +"MAR00027" "" "" "" "" "" "HMR_0027" "" "HMR_0027" "RCR21052" "" 0 "" "" "HMR_0027" +"MAR00028" "" "" "" "" "" "HMR_0028" "" "HMR_0028" "RCR21053" "" 0 "" "" "HMR_0028" +"MAR00029" "" "" "" "" "" "HMR_0029" "" "HMR_0029" "RCR40953" "" 0 "" "" "HMR_0029" +"MAR05173" "" "" "" "" "" "HMR_5173" "" "HMR_5173" "RCR14475" "" 0 "" "" "HMR_5173" +"MAR05289" "" "" "" "" "" "HMR_5289" "" "HMR_5289" "RCR14478" "" 0 "" "" "HMR_5289" +"MAR13064" "" "" "" "" "" "EX_M01268[e]" "" "" "" "" 0 "" "" "EX_M01268[e]" "MAR01515" "" "MAOX" "" "" "" "MAOX" "MNXR101406" "" "" "" 0 "RHEA:59421" "RHEA:59420" "MAOX" "MAR00039" "" "13DAMPPOX" "" "" "" "13DAMPPOX" "MNXR94687" "" "" "" 0 "" "" "13DAMPPOX" "MAR00096" "" "BUP2" "" "" "" "BUP2" "MNXR96346" "" "" "" 0 "" "" "BUP2" diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml index 2168b4c5..5a78bdcc 100644 --- a/model/Human-GEM.yml +++ b/model/Human-GEM.yml @@ -697,14 +697,6 @@ - charge: 0 - inchis: "" - metFrom: "HMRdatabase" - - !!omap - - id: "MAM00036m" - - name: "(24R,25R)3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA" - - compartment: "m" - - formula: "C48H76N7O21P3S" - - charge: -4 - - inchis: "" - - metFrom: "HMRdatabase" - !!omap - id: "MAM00036x" - name: "(24R,25R)3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA" @@ -8129,14 +8121,6 @@ - charge: -4 - inchis: "" - metFrom: "HMRdatabase" - - !!omap - - id: "MAM00616m" - - name: "25(R)THCA-CoA" - - compartment: "m" - - formula: "C48H76N7O20P3S" - - charge: -4 - - inchis: "" - - metFrom: "HMRdatabase" - !!omap - id: "MAM00616x" - name: "25(R)THCA-CoA" @@ -8161,14 +8145,6 @@ - charge: -4 - inchis: "" - metFrom: "HMRdatabase" - - !!omap - - id: "MAM00618m" - - name: "25(S)THCA-CoA" - - compartment: "m" - - formula: "C48H76N7O20P3S" - - charge: -4 - - inchis: "" - - metFrom: "HMRdatabase" - !!omap - id: "MAM00618x" - name: "25(S)THCA-CoA" @@ -9769,14 +9745,6 @@ - charge: 0 - inchis: "InChI=1/C27H46O5/c1-15(6-9-22(30)25(2,3)32)18-7-8-19-24-20(14-23(31)27(18,19)5)26(4)11-10-17(28)12-16(26)13-21(24)29/h15-21,23-24,28-29,31-32H,6-14H2,1-5H3/t15?,16?,17?,18-,19?,20?,21?,23?,24?,26+,27-/s2" - metFrom: "HMRdatabase" - - !!omap - - id: "MAM00748m" - - name: "3alpha,7alpha,12alpha-trihydroxy-5beta-24-oxocholestanoyl-CoA" - - compartment: "m" - - formula: "C48H74N7O21P3S" - - charge: -4 - - inchis: "" - - metFrom: "HMRdatabase" - !!omap - id: "MAM00748x" - name: "3alpha,7alpha,12alpha-trihydroxy-5beta-24-oxocholestanoyl-CoA" @@ -9785,14 +9753,6 @@ - charge: -4 - inchis: "" - metFrom: "HMRdatabase" - - !!omap - - id: "MAM00749m" - - name: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA" - - compartment: "m" - - formula: "C48H74N7O20P3S" - - charge: -4 - - inchis: "" - - metFrom: "HMRdatabase" - !!omap - id: "MAM00749x" - name: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA" @@ -15977,54 +15937,6 @@ - charge: -2 - inchis: "" - metFrom: "HMRdatabase" - - !!omap - - id: "MAM01268c" - - name: "activation-ppara" - - compartment: "c" - - formula: "C2303H3655N619O695S34R" - - charge: 0 - - inchis: "" - - metFrom: "HMRdatabase" - - !!omap - - id: "MAM01268m" - - name: "activation-ppara" - - compartment: "m" - - formula: "C2303H3655N619O695S34R" - - charge: 0 - - inchis: "" - - metFrom: "HMRdatabase" - - !!omap - - id: "MAM01268n" - - name: "activation-ppara" - - compartment: "n" - - formula: "C2303H3655N619O695S34R" - - charge: 0 - - inchis: "" - - metFrom: "HMRdatabase" - - !!omap - - id: "MAM01268x" - - name: "activation-ppara" - - compartment: "x" - - formula: "C2303H3655N619O695S34R" - - charge: 0 - - inchis: "" - - metFrom: "HMRdatabase" - - !!omap - - id: "MAM01268r" - - name: "activation-ppara" - - compartment: "r" - - formula: "C2303H3655N619O695S34R" - - charge: 0 - - inchis: "" - - metFrom: "HMRdatabase" - - !!omap - - id: "MAM01268e" - - name: "activation-ppara" - - compartment: "e" - - formula: "C2303H3655N619O695S34R" - - charge: 0 - - inchis: "" - - metFrom: "HMRdatabase" - !!omap - id: "MAM01269c" - name: "acyl-CoA-bile-PC pool" @@ -18777,14 +18689,6 @@ - charge: -1 - inchis: "" - metFrom: "HMRdatabase" - - !!omap - - id: "MAM01445m" - - name: "cholate" - - compartment: "m" - - formula: "C24H39O5" - - charge: -1 - - inchis: "" - - metFrom: "HMRdatabase" - !!omap - id: "MAM01445x" - name: "cholate" @@ -19961,14 +19865,6 @@ - charge: -4 - inchis: "" - metFrom: "HMRdatabase" - - !!omap - - id: "MAM01514m" - - name: "choloyl-CoA" - - compartment: "m" - - formula: "C45H70N7O20P3S" - - charge: -4 - - inchis: "" - - metFrom: "HMRdatabase" - !!omap - id: "MAM01514x" - name: "choloyl-CoA" @@ -24929,14 +24825,6 @@ - charge: -1 - inchis: "" - metFrom: "HMRdatabase" - - !!omap - - id: "MAM01816n" - - name: "fatty acid-ligands" - - compartment: "n" - - formula: "R" - - charge: 0 - - inchis: "" - - metFrom: "HMRdatabase" - !!omap - id: "MAM01819e" - name: "fatty acid-uptake pool" @@ -38017,30 +37905,6 @@ - charge: -1 - inchis: "" - metFrom: "HMRdatabase" - - !!omap - - id: "MAM02757c" - - name: "PPARA" - - compartment: "c" - - formula: "C2303H3655N619O695S34" - - charge: 0 - - inchis: "" - - metFrom: "HMRdatabase" - - !!omap - - id: "MAM02757l" - - name: "PPARA" - - compartment: "l" - - formula: "C2303H3655N619O695S34" - - charge: 0 - - inchis: "" - - metFrom: "HMRdatabase" - - !!omap - - id: "MAM02757n" - - name: "PPARA" - - compartment: "n" - - formula: "C2303H3655N619O695S34" - - charge: 0 - - inchis: "" - - metFrom: "HMRdatabase" - !!omap - id: "MAM02758c" - name: "PPE-NME2-LD pool" @@ -48705,14 +48569,6 @@ - charge: -4 - inchis: "" - metFrom: "Recon3D" - - !!omap - - id: "MAM03367m" - - name: "24(R),25(R)-Varanoyl Coenzyme A" - - compartment: "m" - - formula: "C48H76N7O21P3S" - - charge: -4 - - inchis: "" - - metFrom: "Recon3D" - !!omap - id: "MAM03367x" - name: "24(R),25(R)-Varanoyl Coenzyme A" @@ -92163,64 +92019,6 @@ - subsystem: - "Protein assembly" - confidence_score: 0 - - !!omap - - id: "MAR05173" - - name: "" - - metabolites: !!omap - - MAM01285c: 1404 - - MAM01371c: -1404 - - MAM02006c: -28 - - MAM02039c: 1863 - - MAM02040c: -1405 - - MAM02335c: -31 - - MAM02340c: -19 - - MAM02341c: -19 - - MAM02342c: -27 - - MAM02351c: -19 - - MAM02376c: -16 - - MAM02377c: -34 - - MAM02380c: -13 - - MAM02401c: -29 - - MAM02404c: -47 - - MAM02405c: -33 - - MAM02408c: -15 - - MAM02412c: -22 - - MAM02415c: -20 - - MAM02416c: -37 - - MAM02419c: -18 - - MAM02421c: -14 - - MAM02423c: -27 - - MAM02751c: 1404 - - MAM02757c: 1 - - MAM03063c: 31 - - MAM03064c: 19 - - MAM03065c: 19 - - MAM03066c: 27 - - MAM03067c: 19 - - MAM03068c: 16 - - MAM03069c: 34 - - MAM03070c: 28 - - MAM03071c: 13 - - MAM03072c: 29 - - MAM03073c: 47 - - MAM03074c: 33 - - MAM03075c: 15 - - MAM03076c: 22 - - MAM03077c: 20 - - MAM03078c: 37 - - MAM03079c: 18 - - MAM03081c: 14 - - MAM03082c: 27 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Protein assembly" - - confidence_score: 0 - !!omap - id: "MAR05174" - name: "" @@ -93652,45 +93450,6 @@ - subsystem: - "Protein degradation" - confidence_score: 0 - - !!omap - - id: "MAR05289" - - name: "" - - metabolites: !!omap - - MAM01285l: 467 - - MAM01307l: 31 - - MAM01365l: 19 - - MAM01369l: 19 - - MAM01370l: 27 - - MAM01371l: -467 - - MAM01628l: 19 - - MAM01974l: 34 - - MAM01975l: 16 - - MAM01986l: 28 - - MAM02039l: 476 - - MAM02040l: -934 - - MAM02125l: 13 - - MAM02184l: 29 - - MAM02360l: 47 - - MAM02426l: 33 - - MAM02471l: 15 - - MAM02724l: 22 - - MAM02751l: 467 - - MAM02757l: -1 - - MAM02770l: 20 - - MAM02896l: 37 - - MAM02993l: 18 - - MAM03101l: 14 - - MAM03135l: 27 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000064601 or ENSG00000100448 or ENSG00000100600 or ENSG00000101160 or ENSG00000103811 or ENSG00000109861 or ENSG00000117984 or ENSG00000135047 or ENSG00000136943 or ENSG00000143387 or ENSG00000163131 or ENSG00000164733 or ENSG00000166340 or ENSG00000172543 or ENSG00000174080 or ENSG00000196188 or ENSG00000256043" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Protein degradation" - - confidence_score: 0 - !!omap - id: "MAR05290" - name: "" @@ -122740,42 +122499,6 @@ - subsystem: - "Terpenoid backbone biosynthesis" - confidence_score: 0 - - !!omap - - id: "MAR01644" - - name: "(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA-forming]" - - metabolites: !!omap - - MAM00036m: 1 - - MAM00749m: -1 - - MAM02040m: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000060971 and ENSG00000113790 and ENSG00000133835" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "4.2.1.107" - - references: "PMID:10709654" - - subsystem: - - "Steroid metabolism" - - confidence_score: 0 - - !!omap - - id: "MAR01651" - - name: "(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA:NAD+ oxidoreductase" - - metabolites: !!omap - - MAM00036m: -1 - - MAM00748m: 1 - - MAM02039m: 1 - - MAM02552m: -1 - - MAM02553m: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000072506 and ENSG00000084754 and ENSG00000138796" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "1.1.1.35;1.1.1.211" - - references: "PMID:10709654" - - subsystem: - - "Steroid metabolism" - - confidence_score: 0 - !!omap - id: "MAR01920" - name: "Cholesterol-sulfate sulfohydrolase" @@ -139874,103 +139597,6 @@ - subsystem: - "Ether lipid metabolism" - confidence_score: 0 - - !!omap - - id: "MAR00024" - - name: "" - - metabolites: !!omap - - MAM01268n: 1 - - MAM01816n: -1 - - MAM02757n: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "(ENSG00000101849 and ENSG00000141027 and ENSG00000171720 and ENSG00000177565 and ENSG00000196498) or (ENSG00000005339 and ENSG00000124151 and ENSG00000140396) or (ENSG00000169375 and ENSG00000196498) or (ENSG00000141027 and ENSG00000169375) or (ENSG00000141027 and ENSG00000169375 and ENSG00000171720 and ENSG00000196498) or ENSG00000069667 or ENSG00000084676 or ENSG00000126368 or ENSG00000137574 or ENSG00000142453 or ENSG00000163586 or ENSG00000186350 or ENSG00000186951 or ENSG00000198646" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Isolated" - - confidence_score: 0 - - !!omap - - id: "MAR00025" - - name: "" - - metabolites: !!omap - - MAM01268c: 1 - - MAM01268n: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000065833 or ENSG00000105398 or ENSG00000112972 or ENSG00000130304 or ENSG00000139278 or ENSG00000143344 or ENSG00000147872 or ENSG00000170485 or ENSG00000198431" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "PMID:12505311;PMID:14999402;PMID:19710929;PMID:17604218;PMID:16476485;PMID:18288277;PMID:16503871;PMID:10529898;PMID:11330046" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR00026" - - name: "" - - metabolites: !!omap - - MAM01268c: -1 - - MAM01268r: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000079459 or ENSG00000113161 or ENSG00000140465 or ENSG00000149485 or ENSG00000167910 or ENSG00000187048 or ENSG00000241119" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "PMID:12505311;PMID:14999402;PMID:19710929;PMID:17604218;PMID:16476485;PMID:18288277;PMID:16503871;PMID:10529898;PMID:11330046" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR00027" - - name: "" - - metabolites: !!omap - - MAM01268c: -1 - - MAM01268m: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000023330 or ENSG00000110090 or ENSG00000117054 or ENSG00000134240 or ENSG00000151726 or ENSG00000157184" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "PMID:12505311;PMID:14999402;PMID:19710929;PMID:17604218;PMID:16476485;PMID:18288277;PMID:16503871;PMID:10529898;PMID:11330046" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR00028" - - name: "" - - metabolites: !!omap - - MAM01268c: -1 - - MAM01268x: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000161533 or ENSG00000166821" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "PMID:12505311;PMID:14999402;PMID:19710929;PMID:17604218;PMID:16476485;PMID:18288277;PMID:16503871;PMID:10529898;PMID:11330046" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR00029" - - name: "" - - metabolites: !!omap - - MAM01268c: -1 - - MAM01268e: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000005471 or ENSG00000118137 or ENSG00000135218 or ENSG00000135744 or ENSG00000158874 or ENSG00000165029 or ENSG00000167772" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "PMID:12505311;PMID:14999402;PMID:19710929;PMID:17604218;PMID:16476485;PMID:18288277;PMID:16503871;PMID:10529898;PMID:11330046" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR07200" - name: "" @@ -145283,22 +144909,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR01630" - - name: "" - - metabolites: !!omap - - MAM00616c: -1 - - MAM00616m: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000180432" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "1.14.13.95" - - references: "PMID:12543708" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR01631" - name: "" @@ -145331,40 +144941,6 @@ - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 - - !!omap - - id: "MAR01635" - - name: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA 25-epimerase" - - metabolites: !!omap - - MAM00616m: -1 - - MAM00618m: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000242110" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "5.1.99.4" - - references: "PMID:11864182;PMID:11060344;PMID:10709654;PMID:11060344;PMID:11060344" - - subsystem: - - "Bile acid biosynthesis" - - confidence_score: 0 - - !!omap - - id: "MAR01637" - - name: "" - - metabolites: !!omap - - MAM00618m: -1 - - MAM00749m: 1 - - MAM02041m: 1 - - MAM02630m: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000087008 or ENSG00000161533" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "1.3.3.6;1.17.99.-" - - references: "PMID:10709654" - - subsystem: - - "Bile acid biosynthesis" - - confidence_score: 0 - !!omap - id: "MAR01638" - name: "" @@ -145381,7 +144957,7 @@ - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "1.3.3.6;1.17.99.-" - - references: "" + - references: "PMID:10709654" - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 @@ -145399,7 +144975,7 @@ - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "1.3.3.6;1.17.99.-" - - references: "PMID:11356170;PMID:8943006" + - references: "PMID:11356170;PMID:8943006;PMID:10709654" - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 @@ -145416,7 +144992,7 @@ - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "4.2.1.107" - - references: "PMID:8902629" + - references: "PMID:8902629;PMID:10709654" - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 @@ -145435,7 +145011,7 @@ - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "1.1.1.35;1.1.1.211" - - references: "PMID:11330072" + - references: "PMID:11330072;PMID:10709654" - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 @@ -145457,40 +145033,6 @@ - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 - - !!omap - - id: "MAR01653" - - name: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase" - - metabolites: !!omap - - MAM00748m: -1 - - MAM01514m: 1 - - MAM01597m: -1 - - MAM02774m: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000060971 or ENSG00000116171 or ENSG00000167306" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "2.3.1.176;2.3.1.16" - - references: "PMID:1121274;PMID:11356164;PMID:6378901" - - subsystem: - - "Bile acid biosynthesis" - - confidence_score: 0 - - !!omap - - id: "MAR01656" - - name: "" - - metabolites: !!omap - - MAM01514c: -1 - - MAM01514x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "PMID:10884298;PMID:6469982" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR01659" - name: "" @@ -145508,7 +145050,7 @@ - rxnNotes: "" - rxnFrom: "HMRdatabase" - eccodes: "" - - references: "PMID:18619829" + - references: "PMID:18619829;PMID:6469982" - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 @@ -145531,25 +145073,6 @@ - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 - - !!omap - - id: "MAR01662" - - name: "choloyl-CoA hydrolase" - - metabolites: !!omap - - MAM01445m: 1 - - MAM01514m: -1 - - MAM01597m: 1 - - MAM02039m: 1 - - MAM02040m: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000101473" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "3.1.2.27" - - references: "PMID:11454857;PMID:10944470;PMID:10817395;PMID:11673457" - - subsystem: - - "Bile acid biosynthesis" - - confidence_score: 0 - !!omap - id: "MAR01663" - name: "choloyl-CoA hydrolase" @@ -145585,22 +145108,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR01666" - - name: "" - - metabolites: !!omap - - MAM01445c: 1 - - MAM01445m: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000083807 or ENSG00000140284" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "6.2.1.7" - - references: "PMID:12543708" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR01667" - name: "Choloyl-CoA:glycine N-choloyltransferase" @@ -199616,24 +199123,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR07758" - - name: "" - - metabolites: !!omap - - MAM01514c: -1 - - MAM01514m: 1 - - MAM02039i: -1 - - MAM02039m: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000155368" - - rxnNotes: "" - - rxnFrom: "HMRdatabase" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR07760" - name: "" @@ -224523,27 +224012,6 @@ - subsystem: - "Bile acid biosynthesis" - confidence_score: 0 - - !!omap - - id: "MAR01458" - - name: "Hydroxysteroid (17-Beta) Dehydrogenase 4" - - metabolites: !!omap - - MAM00748x: 1 - - MAM00749x: -1 - - MAM02039x: -1 - - MAM02040x: 1 - - MAM02554x: 1 - - MAM02555x: -1 - - MAM02630x: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000133835" - - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "3.10.1.1" - - references: "" - - subsystem: - - "Bile acid biosynthesis" - - confidence_score: 0 - !!omap - id: "MAR01461" - name: "H Transporter, Endoplasmic Reticulum" @@ -225306,11 +224774,11 @@ - MAM02519e: -1 - lower_bound: -1000 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000100170 or ENSG00000105641 or ENSG00000198743" + - gene_reaction_rule: "ENSG00000144285 or ENSG00000136531 or ENSG00000153253 or ENSG00000007314 or ENSG00000183873 or ENSG00000136546 or ENSG00000196876 or ENSG00000169432 or ENSG00000185313 or ENSG00000168356 or ENSG00000164588 or ENSG00000138622 or ENSG00000186815 or ENSG00000162341 or ENSG00000102452 or (ENSG00000111319 and ENSG00000168447 and ENSG00000166828) or ENSG00000162572" - rxnNotes: "" - rxnFrom: "Recon3D" - eccodes: "" - - references: "PMID:10893432;PMID:11024018;PMID:11034615;PMID:12679487;PMID:12748858;PMID:1372904;PMID:15546855;PMID:2490366;PMID:7537337;PMID:7789985;PMID:8063771;PMID:8559252;PMID:8806637;PMID:9341168" + - references: "PMID:10893432;PMID:11024018;PMID:11034615;PMID:12679487;PMID:12748858;PMID:1372904;PMID:15546855;PMID:2490366;PMID:7537337;PMID:7789985;PMID:8063771;PMID:8559252;PMID:8806637;PMID:9341168;PMID:22573384;PMID:26772908" - subsystem: - "Transport reactions" - confidence_score: 0 @@ -235301,23 +234769,6 @@ - subsystem: - "Fatty acid biosynthesis" - confidence_score: 0 - - !!omap - - id: "MAR03754" - - name: "Enoyl Coenzyme A Hydratase" - - metabolites: !!omap - - MAM00749m: -1 - - MAM02040m: -1 - - MAM03367m: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000084754 or ENSG00000113790 or ENSG00000127884 or ENSG00000138029" - - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "4.2.1.17" - - references: "PMID:10709654" - - subsystem: - - "Fatty acid oxidation" - - confidence_score: 0 - !!omap - id: "MAR03756" - name: "Enoyl Coenzyme A Hydratase" @@ -235354,25 +234805,6 @@ - subsystem: - "Fatty acid oxidation" - confidence_score: 0 - - !!omap - - id: "MAR03760" - - name: "3-Hydroxyacyl Coenzyme A Dehydrogenase" - - metabolites: !!omap - - MAM00748m: 1 - - MAM02039m: 1 - - MAM02552m: -1 - - MAM02553m: 1 - - MAM03367m: -1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000072506 or ENSG00000113790 or ENSG00000133835 or ENSG00000138796" - - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "1.1.1.35" - - references: "PMID:10709654" - - subsystem: - - "Fatty acid oxidation" - - confidence_score: 0 - !!omap - id: "MAR03764" - name: "3-Hydroxyacyl Coenzyme A Dehydrogenase" @@ -300694,21 +300126,6 @@ - subsystem: - "Exchange/demand reactions" - confidence_score: 0 - - !!omap - - id: "MAR13064" - - name: "EX_M01268[e]" - - metabolites: !!omap - - MAM01268e: -1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - rxnFrom: "Recon3D" - - eccodes: "" - - references: "" - - subsystem: - - "Exchange/demand reactions" - - confidence_score: 0 - !!omap - id: "MAR13065" - name: "EX_HC02080[e]" @@ -305602,6 +305019,9 @@ - !!omap - id: "ENSG00000007216" - name: "SLC13A2" + - !!omap + - id: "ENSG00000007314" + - name: "SCN4A" - !!omap - id: "ENSG00000007350" - name: "TKTL1" @@ -306130,9 +305550,6 @@ - !!omap - id: "ENSG00000069535" - name: "MAOB" - - !!omap - - id: "ENSG00000069667" - - name: "RORA" - !!omap - id: "ENSG00000069764" - name: "PLA2G10" @@ -306991,9 +306408,6 @@ - !!omap - id: "ENSG00000101846" - name: "STS" - - !!omap - - id: "ENSG00000101849" - - name: "TBL1X" - !!omap - id: "ENSG00000101868" - name: "POLA1" @@ -307063,6 +306477,9 @@ - !!omap - id: "ENSG00000102393" - name: "GLA" + - !!omap + - id: "ENSG00000102452" + - name: "NALCN" - !!omap - id: "ENSG00000102575" - name: "ACP5" @@ -307702,6 +307119,9 @@ - !!omap - id: "ENSG00000111275" - name: "ALDH2" + - !!omap + - id: "ENSG00000111319" + - name: "SCNN1A" - !!omap - id: "ENSG00000111339" - name: "ART4" @@ -308254,9 +307674,6 @@ - !!omap - id: "ENSG00000118094" - name: "TREH" - - !!omap - - id: "ENSG00000118137" - - name: "APOA1" - !!omap - id: "ENSG00000118160" - name: "SLC8A2" @@ -308683,9 +308100,6 @@ - !!omap - id: "ENSG00000126267" - name: "COX6B1" - - !!omap - - id: "ENSG00000126368" - - name: "NR1D1" - !!omap - id: "ENSG00000126432" - name: "PRDX5" @@ -309316,9 +308730,6 @@ - !!omap - id: "ENSG00000135740" - name: "SLC9A5" - - !!omap - - id: "ENSG00000135744" - - name: "AGT" - !!omap - id: "ENSG00000135778" - name: "NTPCR" @@ -309385,12 +308796,18 @@ - !!omap - id: "ENSG00000136521" - name: "NDUFB5" + - !!omap + - id: "ENSG00000136531" + - name: "SCN2A" - !!omap - id: "ENSG00000136536" - name: "MARCHF7" - !!omap - id: "ENSG00000136542" - name: "GALNT5" + - !!omap + - id: "ENSG00000136546" + - name: "SCN7A" - !!omap - id: "ENSG00000136628" - name: "EPRS1" @@ -309478,9 +308895,6 @@ - !!omap - id: "ENSG00000137563" - name: "GGH" - - !!omap - - id: "ENSG00000137574" - - name: "TGS1" - !!omap - id: "ENSG00000137731" - name: "FXYD2" @@ -309604,6 +309018,9 @@ - !!omap - id: "ENSG00000138621" - name: "PPCDC" + - !!omap + - id: "ENSG00000138622" + - name: "HCN4" - !!omap - id: "ENSG00000138641" - name: "HERC3" @@ -309670,9 +309087,6 @@ - !!omap - id: "ENSG00000139266" - name: "MARCHF9" - - !!omap - - id: "ENSG00000139278" - - name: "GLIPR1" - !!omap - id: "ENSG00000139287" - name: "TPH2" @@ -309769,9 +309183,6 @@ - !!omap - id: "ENSG00000140374" - name: "ETFA" - - !!omap - - id: "ENSG00000140396" - - name: "NCOA2" - !!omap - id: "ENSG00000140400" - name: "MAN2C1" @@ -309829,9 +309240,6 @@ - !!omap - id: "ENSG00000141012" - name: "GALNS" - - !!omap - - id: "ENSG00000141027" - - name: "NCOR1" - !!omap - id: "ENSG00000141096" - name: "DPEP3" @@ -309928,9 +309336,6 @@ - !!omap - id: "ENSG00000142319" - name: "SLC6A3" - - !!omap - - id: "ENSG00000142453" - - name: "CARM1" - !!omap - id: "ENSG00000142494" - name: "SLC47A1" @@ -310003,9 +309408,6 @@ - !!omap - id: "ENSG00000143324" - name: "XPR1" - - !!omap - - id: "ENSG00000143344" - - name: "RGL1" - !!omap - id: "ENSG00000143363" - name: "PRUNE1" @@ -310111,6 +309513,9 @@ - !!omap - id: "ENSG00000144278" - name: "GALNT13" + - !!omap + - id: "ENSG00000144285" + - name: "SCN1A" - !!omap - id: "ENSG00000144290" - name: "SLC4A10" @@ -310597,6 +310002,9 @@ - !!omap - id: "ENSG00000153207" - name: "AHCTF1" + - !!omap + - id: "ENSG00000153253" + - name: "SCN3A" - !!omap - id: "ENSG00000153291" - name: "SLC25A27" @@ -310903,9 +310311,6 @@ - !!omap - id: "ENSG00000158865" - name: "SLC5A11" - - !!omap - - id: "ENSG00000158874" - - name: "APOA2" - !!omap - id: "ENSG00000159063" - name: "ALG8" @@ -311122,6 +310527,9 @@ - !!omap - id: "ENSG00000162298" - name: "SYVN1" + - !!omap + - id: "ENSG00000162341" + - name: "TPCN2" - !!omap - id: "ENSG00000162365" - name: "CYP4A22" @@ -311155,6 +310563,9 @@ - !!omap - id: "ENSG00000162551" - name: "ALPL" + - !!omap + - id: "ENSG00000162572" + - name: "SCNN1D" - !!omap - id: "ENSG00000162607" - name: "USP1" @@ -311401,6 +310812,9 @@ - !!omap - id: "ENSG00000164574" - name: "GALNT10" + - !!omap + - id: "ENSG00000164588" + - name: "HCN1" - !!omap - id: "ENSG00000164638" - name: "SLC29A4" @@ -311644,12 +311058,12 @@ - !!omap - id: "ENSG00000166819" - name: "PLIN1" - - !!omap - - id: "ENSG00000166821" - - name: "PEX11A" - !!omap - id: "ENSG00000166825" - name: "ANPEP" + - !!omap + - id: "ENSG00000166828" + - name: "SCNN1G" - !!omap - id: "ENSG00000166840" - name: "GLYATL1" @@ -311776,9 +311190,6 @@ - !!omap - id: "ENSG00000167769" - name: "ACER1" - - !!omap - - id: "ENSG00000167772" - - name: "ANGPTL4" - !!omap - id: "ENSG00000167780" - name: "SOAT2" @@ -311851,12 +311262,18 @@ - !!omap - id: "ENSG00000168350" - name: "DEGS2" + - !!omap + - id: "ENSG00000168356" + - name: "SCN11A" - !!omap - id: "ENSG00000168393" - name: "DTYMK" - !!omap - id: "ENSG00000168411" - name: "RFWD3" + - !!omap + - id: "ENSG00000168447" + - name: "SCNN1B" - !!omap - id: "ENSG00000168487" - name: "BMP1" @@ -311935,12 +311352,12 @@ - !!omap - id: "ENSG00000169359" - name: "SLC33A1" - - !!omap - - id: "ENSG00000169375" - - name: "SIN3A" - !!omap - id: "ENSG00000169418" - name: "NPR1" + - !!omap + - id: "ENSG00000169432" + - name: "SCN9A" - !!omap - id: "ENSG00000169660" - name: "HEXD" @@ -312022,9 +311439,6 @@ - !!omap - id: "ENSG00000170482" - name: "SLC23A1" - - !!omap - - id: "ENSG00000170485" - - name: "NPAS2" - !!omap - id: "ENSG00000170502" - name: "NUDT9" @@ -312130,9 +311544,6 @@ - !!omap - id: "ENSG00000171608" - name: "PIK3CD" - - !!omap - - id: "ENSG00000171720" - - name: "HDAC3" - !!omap - id: "ENSG00000171723" - name: "GPHN" @@ -312586,9 +311997,6 @@ - !!omap - id: "ENSG00000177542" - name: "SLC25A22" - - !!omap - - id: "ENSG00000177565" - - name: "TBL1XR1" - !!omap - id: "ENSG00000177628" - name: "GBA" @@ -312913,6 +312321,9 @@ - !!omap - id: "ENSG00000183828" - name: "NUDT14" + - !!omap + - id: "ENSG00000183873" + - name: "SCN5A" - !!omap - id: "ENSG00000183921" - name: "SDR42E2" @@ -313006,6 +312417,9 @@ - !!omap - id: "ENSG00000185274" - name: "GALNT17" + - !!omap + - id: "ENSG00000185313" + - name: "SCN10A" - !!omap - id: "ENSG00000185344" - name: "ATP6V0A2" @@ -313099,9 +312513,6 @@ - !!omap - id: "ENSG00000186335" - name: "SLC36A2" - - !!omap - - id: "ENSG00000186350" - - name: "RXRA" - !!omap - id: "ENSG00000186377" - name: "CYP4X1" @@ -313120,12 +312531,12 @@ - !!omap - id: "ENSG00000186792" - name: "HYAL3" + - !!omap + - id: "ENSG00000186815" + - name: "TPCN1" - !!omap - id: "ENSG00000186908" - name: "ZDHHC17" - - !!omap - - id: "ENSG00000186951" - - name: "PPARA" - !!omap - id: "ENSG00000187021" - name: "PNLIPRP1" @@ -313276,9 +312687,6 @@ - !!omap - id: "ENSG00000196475" - name: "GK2" - - !!omap - - id: "ENSG00000196498" - - name: "NCOR2" - !!omap - id: "ENSG00000196502" - name: "SULT1A1" @@ -313303,6 +312711,9 @@ - !!omap - id: "ENSG00000196839" - name: "ADA" + - !!omap + - id: "ENSG00000196876" + - name: "SCN8A" - !!omap - id: "ENSG00000196950" - name: "SLC39A10" @@ -313501,9 +312912,6 @@ - !!omap - id: "ENSG00000198610" - name: "AKR1C4" - - !!omap - - id: "ENSG00000198646" - - name: "NCOA6" - !!omap - id: "ENSG00000198650" - name: "TAT" diff --git a/model/genes.tsv b/model/genes.tsv index b24b8417..4b17c98d 100644 --- a/model/genes.tsv +++ b/model/genes.tsv @@ -217,7 +217,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000069248" "ENST00000261396;ENST00000490352;ENST00000485119;ENST00000366678" "ENSP00000261396" "Q8WUM0" "NUP133" "55746" "nucleoporin 133" "FLJ10814" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000069431" "ENST00000261200;ENST00000683676;ENST00000683695;ENST00000682426;ENST00000683105;ENST00000684084;ENST00000682879;ENST00000261201;ENST00000544039;ENST00000683811;ENST00000682068;ENST00000684543;ENST00000682789;ENST00000326684;ENST00000621589;ENST00000538350;ENST00000684435;ENST00000636888;ENST00000682646;ENST00000683560" "ENSP00000261200;ENSP00000508167;ENSP00000506801;ENSP00000507859;ENSP00000508210;ENSP00000261201;ENSP00000440521;ENSP00000507226;ENSP00000317518;ENSP00000480233;ENSP00000442604;ENSP00000507779;ENSP00000490640" "O60706" "ABCC9" "10060" "ATP binding cassette subfamily C member 9" "CMD1O;SUR2" "Cytosol;Nucleus" "CellAtlas" "ENSG00000069535" "ENST00000378069;ENST00000487544;ENST00000468431" "ENSP00000367309" "P27338" "MAOB" "4129" "monoamine oxidase B" "" "Cytosol" "SwissProt" -"ENSG00000069667" "ENST00000335670;ENST00000309157;ENST00000261523;ENST00000449337;ENST00000559587;ENST00000551975;ENST00000560004;ENST00000559343;ENST00000558234;ENST00000557822;ENST00000559145;ENST00000561093;ENST00000560300;ENST00000558904" "ENSP00000335087;ENSP00000309753;ENSP00000261523;ENSP00000402971;ENSP00000449482;ENSP00000453322;ENSP00000484955" "P35398" "RORA" "6095" "RAR related orphan receptor A" "NR1F1;ROR1;ROR2;ROR3;RZRA" "Nucleus" "SwissProt;CellAtlas" "ENSG00000069764" "ENST00000438167;ENST00000567462" "ENSP00000393847;ENSP00000456433" "O15496" "PLA2G10" "8399" "phospholipase A2 group X" "GXPLA2" "Cytosol;Lysosome" "SwissProt" "ENSG00000069849" "ENST00000475483;ENST00000286371;ENST00000465172;ENST00000466678;ENST00000462082;ENST00000495216;ENST00000482635;ENST00000487199;ENST00000484727;ENST00000486782" "ENSP00000417522;ENSP00000286371;ENSP00000418280;ENSP00000418952;ENSP00000418353;ENSP00000419962;ENSP00000417608" "P54709" "ATP1B3" "483" "ATPase Na+/K+ transporting subunit beta 3" "CD298;FLJ29027" "Cell membrane" "DeepLoc2" "ENSG00000069869" "ENST00000508871;ENST00000503468;ENST00000338963;ENST00000508342;ENST00000435532;ENST00000648451;ENST00000506154;ENST00000502612;ENST00000514893;ENST00000507063;ENST00000513957;ENST00000508075;ENST00000557845" "ENSP00000422455;ENSP00000426051;ENSP00000345530;ENSP00000424827;ENSP00000410613;ENSP00000498181;ENSP00000422705;ENSP00000424471;ENSP00000421047" "P46934" "NEDD4" "4734" "NEDD4 E3 ubiquitin protein ligase" "KIAA0093;MGC176705;NEDD4-1;RPF1" "Nucleus;Cytosol" "SwissProt;CellAtlas" @@ -504,7 +503,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000101751" "ENST00000579534;ENST00000406285;ENST00000577612;ENST00000579434;ENST00000583136;ENST00000577971;ENST00000217800;ENST00000580880;ENST00000580905;ENST00000581950;ENST00000585023;ENST00000579823;ENST00000577361;ENST00000583576;ENST00000582366;ENST00000577727" "ENSP00000462664;ENSP00000385196;ENSP00000464025;ENSP00000462681;ENSP00000463071;ENSP00000217800;ENSP00000461983;ENSP00000462146;ENSP00000463971;ENSP00000463065" "Q9UNA4" "POLI" "11201" "DNA polymerase iota" "RAD30B;RAD3OB" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000101752" "ENST00000578646;ENST00000261537;ENST00000577749;ENST00000578260" "ENSP00000261537" "Q86YT6" "MIB1" "57534" "MIB E3 ubiquitin protein ligase 1" "DIP-1;KIAA1323;MIB;ZZANK2;ZZZ6" "Cytosol" "SwissProt" "ENSG00000101846" "ENST00000664306;ENST00000666110;ENST00000674429;ENST00000660000;ENST00000658154;ENST00000217961;ENST00000674499" "ENSP00000499549;ENSP00000499472;ENSP00000501534;ENSP00000499642;ENSP00000217961;ENSP00000501360" "P08842" "STS" "412" "steroid sulfatase" "ARSC;ARSC1" "Cytosol;Endoplasmic reticulum" "SwissProt" -"ENSG00000101849" "ENST00000407597;ENST00000380961;ENST00000424279;ENST00000645353;ENST00000422314;ENST00000645686;ENST00000646640;ENST00000647172;ENST00000452824;ENST00000415293;ENST00000683056;ENST00000647060;ENST00000497555;ENST00000684110" "ENSP00000385988;ENSP00000370348;ENSP00000394097;ENSP00000496215;ENSP00000415508;ENSP00000493782;ENSP00000495556;ENSP00000495835;ENSP00000397878;ENSP00000507708;ENSP00000495467" "O60907" "TBL1X" "6907" "transducin beta like 1 X-linked" "EBI;TBL1" "Nucleus" "SwissProt;CellAtlas" "ENSG00000101868" "ENST00000678847;ENST00000672178;ENST00000379068;ENST00000677890;ENST00000379059;ENST00000676703;ENST00000611764;ENST00000493342;ENST00000678249;ENST00000480125;ENST00000677083;ENST00000679301;ENST00000494204;ENST00000677939" "ENSP00000500742;ENSP00000368358;ENSP00000503099;ENSP00000368349" "P09884" "POLA1" "5422" "DNA polymerase alpha 1, catalytic subunit" "NSX;p180;POLA" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000101871" "ENST00000453318;ENST00000380779;ENST00000380780;ENST00000317552;ENST00000380785;ENST00000380787;ENST00000380782;ENST00000675073;ENST00000674917;ENST00000479925;ENST00000413894;ENST00000616003;ENST00000675358;ENST00000610939" "ENSP00000414521;ENSP00000370156;ENSP00000370157;ENSP00000312678;ENSP00000370162;ENSP00000370164;ENSP00000370159;ENSP00000501707;ENSP00000502171;ENSP00000391154;ENSP00000484712;ENSP00000502220" "O15344" "MID1" "4281" "midline 1" "FXY;OS;RNF59;TRIM18" "Golgi apparatus;Cytosol" "SwissProt;CellAtlas" "ENSG00000101890" "ENST00000218006" "ENSP00000218006" "P51841" "GUCY2F" "2986" "guanylate cyclase 2F, retinal" "CYGF;GC-F;GUC2DL;RetGC-2;ROS-GC2" "Cell membrane" "DeepLoc2" @@ -925,7 +923,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000118017" "ENST00000236709" "ENSP00000236709" "Q9UNA3" "A4GNT" "51146" "alpha-1,4-N-acetylglucosaminyltransferase" "alpha4GnT" "Golgi apparatus" "SwissProt" "ENSG00000118058" "ENST00000389506;ENST00000534358;ENST00000531904;ENST00000649699;ENST00000532204;ENST00000529852;ENST00000533790;ENST00000527869;ENST00000649690;ENST00000648029;ENST00000647638;ENST00000649666;ENST00000648910;ENST00000420751;ENST00000392873;ENST00000649410;ENST00000528278;ENST00000534085;ENST00000647944;ENST00000649878;ENST00000648565;ENST00000534678;ENST00000527839;ENST00000525408" "ENSP00000374157;ENSP00000436786;ENSP00000432391;ENSP00000496927;ENSP00000434618;ENSP00000436564;ENSP00000436700;ENSP00000432652;ENSP00000497372;ENSP00000497918;ENSP00000498134;ENSP00000497891" "Q03164" "KMT2A" "4297" "lysine methyltransferase 2A" "ALL-1;CXXC7;HRX;HTRX1;MLL;MLL1A;TRX1" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000118094" "ENST00000264029;ENST00000613915;ENST00000397925;ENST00000531295;ENST00000527558" "ENSP00000264029;ENSP00000477923;ENSP00000381020" "O43280" "TREH" "11181" "trehalase" "MGC129621;TRE;TREA" "Cytosol" "CellAtlas" -"ENSG00000118137" "ENST00000375320;ENST00000359492;ENST00000375329;ENST00000375323;ENST00000236850" "ENSP00000364469;ENSP00000352471;ENSP00000364478;ENSP00000364472;ENSP00000236850" "P02647" "APOA1" "335" "apolipoprotein A1" "" "Cytosol" "CellAtlas" "ENSG00000118160" "ENST00000236877;ENST00000542837;ENST00000539381;ENST00000600576;ENST00000601757;ENST00000594353;ENST00000597014" "ENSP00000236877;ENSP00000437536;ENSP00000472233;ENSP00000472208" "Q9UPR5" "SLC8A2" "6543" "solute carrier family 8 member A2" "KIAA1087;NCX2" "Cell membrane" "DeepLoc2" "ENSG00000118276" "ENST00000578114;ENST00000306851;ENST00000237019;ENST00000383131;ENST00000579372" "ENSP00000306459;ENSP00000237019;ENSP00000372613;ENSP00000463961" "Q9UBX8" "B4GALT6" "9331" "beta-1,4-galactosyltransferase 6" "beta4GalT-VI" "Golgi apparatus" "SwissProt" "ENSG00000118298" "ENST00000369111;ENST00000647854;ENST00000582010;ENST00000607652;ENST00000483993;ENST00000607082" "ENSP00000358107;ENSP00000498013;ENSP00000475869;ENSP00000475238" "Q9ULX7" "CA14" "23632" "carbonic anhydrase 14" "" "Cell membrane" "DeepLoc2" @@ -1068,7 +1065,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000126107" "ENST00000486132;ENST00000372168;ENST00000372172;ENST00000486296;ENST00000466423;ENST00000487488;ENST00000484564" "ENSP00000361241;ENSP00000361245" "Q5T447" "HECTD3" "79654" "HECT domain E3 ubiquitin protein ligase 3" "FLJ21156" "Cytosol" "SwissProt" "ENSG00000126261" "ENST00000607361;ENST00000586313;ENST00000246548;ENST00000590048;ENST00000592841;ENST00000439527;ENST00000592672;ENST00000591016;ENST00000592791;ENST00000588585" "ENSP00000475565;ENSP00000468538;ENSP00000246548;ENSP00000467433;ENSP00000437484;ENSP00000468756;ENSP00000475656" "Q9UBT2" "UBA2" "10054" "ubiquitin like modifier activating enzyme 2" "FLJ13058;HRIHFB2115;SAE2" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000126267" "ENST00000649813;ENST00000592141;ENST00000392201;ENST00000652250;ENST00000590618" "ENSP00000497926;ENSP00000466818;ENSP00000376037;ENSP00000498883;ENSP00000467776" "P14854" "COX6B1" "1340" "cytochrome c oxidase subunit 6B1" "COX6B;COXG" "Inner mitochondria" "SwissProt;CellAtlas" -"ENSG00000126368" "ENST00000246672" "ENSP00000246672" "P20393" "NR1D1" "9572" "nuclear receptor subfamily 1 group D member 1" "ear-1;hRev;Rev-ErbAalpha;REVERBA;REVERBalpha;THRA1;THRAL" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000126432" "ENST00000265462;ENST00000352435;ENST00000347941" "ENSP00000265462;ENSP00000335334;ENSP00000335363" "P30044" "PRDX5" "25824" "peroxiredoxin 5" "ACR1;AOEB166;B166;MGC117264;MGC142283;MGC142285;PLP;PMP20;PRDX6;PRXV;SBBI10" "Peroxisome;Mitochondria;Cytosol" "SwissProt;CellAtlas" "ENSG00000126522" "ENST00000672586;ENST00000304874;ENST00000673518;ENST00000487982;ENST00000673350;ENST00000672498;ENST00000496336;ENST00000395332;ENST00000672676;ENST00000362000;ENST00000395331;ENST00000671817;ENST00000673594;ENST00000673149;ENST00000493708;ENST00000488343;ENST00000464970;ENST00000380839" "ENSP00000307188;ENSP00000499889;ENSP00000500227;ENSP00000378741;ENSP00000354710;ENSP00000378740;ENSP00000500462;ENSP00000500864;ENSP00000370219" "P04424" "ASL" "435" "argininosuccinate lyase" "ASAL" "Cytosol" "CellAtlas" "ENSG00000126821" "ENST00000247225" "ENSP00000247225" "Q9BX95" "SGPP1" "81537" "sphingosine-1-phosphate phosphatase 1" "" "Endoplasmic reticulum;Nucleus" "SwissProt;CellAtlas" @@ -1279,7 +1275,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000135697" "ENST00000563804;ENST00000258168;ENST00000564552" "ENSP00000457910;ENSP00000258168;ENSP00000455219" "Q9HAY6" "BCO1" "53630" "beta-carotene oxygenase 1" "BCDO;BCDO1;BCMO;BCMO1;FLJ10730" "Cytosol" "SwissProt" "ENSG00000135702" "ENST00000336257;ENST00000565039" "ENSP00000338783;ENSP00000454375" "Q9GZS9" "CHST5" "23563" "carbohydrate sulfotransferase 5" "FLJ22167;I-GLCNAC-6-ST" "Golgi apparatus" "DeepLoc2" "ENSG00000135740" "ENST00000564704;ENST00000566345;ENST00000564812;ENST00000563723;ENST00000561472;ENST00000299798;ENST00000566638;ENST00000567247;ENST00000566626" "ENSP00000462446;ENSP00000455058;ENSP00000299798;ENSP00000464393;ENSP00000462404" "Q14940" "SLC9A5" "6553" "solute carrier family 9 member A5" "NHE5" "Cytosol" "CellAtlas" -"ENSG00000135744" "ENST00000680783;ENST00000679854;ENST00000679802;ENST00000681347;ENST00000681772;ENST00000679738;ENST00000657140;ENST00000681514;ENST00000680041;ENST00000366667;ENST00000681269;ENST00000679957;ENST00000679684" "ENSP00000506329;ENSP00000505184;ENSP00000505829;ENSP00000505063;ENSP00000505963;ENSP00000504866;ENSP00000355627;ENSP00000505985;ENSP00000506646;ENSP00000505981" "P01019" "AGT" "183" "angiotensinogen" "SERPINA8" "Extracellular" "DeepLoc2" "ENSG00000135778" "ENST00000494689;ENST00000490807;ENST00000366628;ENST00000496662;ENST00000366627;ENST00000479125;ENST00000487953;ENST00000490098" "ENSP00000355587;ENSP00000355586" "Q9BSD7" "NTPCR" "84284" "nucleoside-triphosphatase, cancer-related" "C1orf57;HCR-NTPase;MGC13186;THEP1" "Cytosol" "CellAtlas" "ENSG00000135821" "ENST00000642379;ENST00000331872;ENST00000491322;ENST00000339526;ENST00000463851;ENST00000461447;ENST00000484996;ENST00000489818;ENST00000475808;ENST00000480604;ENST00000462444;ENST00000311223;ENST00000417584" "ENSP00000494022;ENSP00000356537;ENSP00000344958;ENSP00000307900;ENSP00000398320" "P15104" "GLUL" "2752" "glutamate-ammonia ligase" "GLNS" "Mitochondria;Cytosol" "SwissProt;CellAtlas" "ENSG00000135838" "ENST00000488424;ENST00000460690;ENST00000463899;ENST00000367555;ENST00000479721;ENST00000471010;ENST00000367553;ENST00000460179;ENST00000367552;ENST00000258317;ENST00000367554;ENST00000614468" "ENSP00000356526;ENSP00000356524;ENSP00000356523;ENSP00000258317;ENSP00000356525;ENSP00000482415" "Q9BXD5" "NPL" "80896" "N-acetylneuraminate pyruvate lyase" "C1orf13;DHDPS1;NPL1" "Cytosol" "SwissProt" @@ -1333,7 +1328,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000137393" "ENST00000259939;ENST00000486622" "ENSP00000259939" "Q7Z419" "RNF144B" "255488" "ring finger protein 144B" "bA528A10.3;IBRDC2;P53RFP" "Mitochondria;Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000137491" "ENST00000526660;ENST00000531713;ENST00000289575;ENST00000532236;ENST00000531756;ENST00000531457;ENST00000525650;ENST00000454962;ENST00000530556;ENST00000534004;ENST00000527180;ENST00000525845;ENST00000534186;ENST00000428359;ENST00000526839;ENST00000530012;ENST00000528108;ENST00000530015;ENST00000341411" "ENSP00000432889;ENSP00000289575;ENSP00000434112;ENSP00000436324;ENSP00000389653;ENSP00000435384;ENSP00000431192;ENSP00000436513;ENSP00000431324;ENSP00000433872;ENSP00000388912;ENSP00000434742" "O94956" "SLCO2B1" "11309" "solute carrier organic anion transporter family member 2B1" "OATP-B;OATP2B1;SLC21A9" "Cell membrane" "DeepLoc2" "ENSG00000137563" "ENST00000518466;ENST00000523788;ENST00000678069;ENST00000677459;ENST00000677482;ENST00000677919;ENST00000260118;ENST00000677327;ENST00000679326;ENST00000522852;ENST00000520609;ENST00000678045;ENST00000518113;ENST00000518966;ENST00000523479" "ENSP00000503731;ENSP00000504590;ENSP00000504579;ENSP00000260118;ENSP00000504262;ENSP00000504520" "Q92820" "GGH" "8836" "gamma-glutamyl hydrolase" "" "Lysosome" "SwissProt" -"ENSG00000137574" "ENST00000260129;ENST00000523948;ENST00000519494" "ENSP00000260129;ENSP00000430467" "Q96RS0" "TGS1" "96764" "trimethylguanosine synthase 1" "NCOA6IP;PIMT" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000137731" "ENST00000514385;ENST00000532119;ENST00000528014;ENST00000292079;ENST00000260287;ENST00000534383;ENST00000533281;ENST00000317594" "ENSP00000436414;ENSP00000432430;ENSP00000292079;ENSP00000260287" "P54710" "FXYD2" "486" "FXYD domain containing ion transport regulator 2" "ATP1G1;HOMG2;MGC12372" "Mitochondria" "CellAtlas" "ENSG00000137770" "ENST00000260327;ENST00000558791;ENST00000560834;ENST00000558966;ENST00000559793;ENST00000558968;ENST00000558373;ENST00000561189;ENST00000560620;ENST00000559738;ENST00000559175" "ENSP00000260327;ENSP00000453612;ENSP00000452837;ENSP00000454187;ENSP00000454154;ENSP00000453051;ENSP00000453538" "Q05D32" "CTDSPL2" "51496" "CTD small phosphatase like 2" "FLJ10523;HSPC129" "Nucleus" "CellAtlas" "ENSG00000137817" "ENST00000569173;ENST00000569795;ENST00000260376;ENST00000616176;ENST00000413097;ENST00000287196;ENST00000569972;ENST00000564610;ENST00000567974;ENST00000544520;ENST00000565443;ENST00000566991;ENST00000567440;ENST00000567263;ENST00000566831;ENST00000419739;ENST00000567042;ENST00000569890;ENST00000568213;ENST00000565999;ENST00000568360;ENST00000566844;ENST00000567633" "ENSP00000456749;ENSP00000456348;ENSP00000260376;ENSP00000484561;ENSP00000287196;ENSP00000456468;ENSP00000455815;ENSP00000456370;ENSP00000454298;ENSP00000457752;ENSP00000403265;ENSP00000455637;ENSP00000455847;ENSP00000457134;ENSP00000457862;ENSP00000457187" "Q2NL67" "PARP6" "56965" "poly(ADP-ribose) polymerase family member 6" "ARTD17;pART17" "Cytosol;Nucleus" "DeepLoc2" @@ -1397,7 +1391,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000139180" "ENST00000539573;ENST00000266544;ENST00000542369;ENST00000396655;ENST00000544679;ENST00000535050;ENST00000535726;ENST00000544675;ENST00000540688" "ENSP00000266544;ENSP00000440305;ENSP00000439818" "Q16795" "NDUFA9" "4704" "NADH:ubiquinone oxidoreductase subunit A9" "CI-39k;COQ11;NDUFS2L;SDR22E1" "Mitochondria;Nucleus" "SwissProt;CellAtlas" "ENSG00000139209" "ENST00000447411;ENST00000266579;ENST00000550670;ENST00000547477;ENST00000546940" "ENSP00000389843;ENSP00000266579;ENSP00000448186;ENSP00000450071;ENSP00000448543" "Q969I6" "SLC38A4" "55089" "solute carrier family 38 member 4" "ATA3;NAT3;PAAT" "Cell membrane;Lysosome" "DeepLoc2" "ENSG00000139266" "ENST00000266643;ENST00000552279;ENST00000548358" "ENSP00000266643;ENSP00000446758" "Q86YJ5" "MARCHF9" "92979" "membrane associated ring-CH-type finger 9" "FLJ36578;MARCH9;RNF179" "Lysosome;Golgi apparatus" "SwissProt" -"ENSG00000139278" "ENST00000536703;ENST00000266659;ENST00000456650;ENST00000550491" "ENSP00000440595;ENSP00000266659;ENSP00000391144;ENSP00000448008" "P48060" "GLIPR1" "11010" "GLI pathogenesis related 1" "GliPR;RTVP1" "Extracellular" "DeepLoc2" "ENSG00000139287" "ENST00000333850;ENST00000546576;ENST00000550403;ENST00000547348;ENST00000551074;ENST00000547278" "ENSP00000329093" "Q8IWU9" "TPH2" "121278" "tryptophan hydroxylase 2" "FLJ37295;NTPH" "Mitochondria" "DeepLoc2" "ENSG00000139304" "ENST00000623635;ENST00000551042;ENST00000547376;ENST00000551573;ENST00000616559;ENST00000644991;ENST00000547485;ENST00000551624;ENST00000547881;ENST00000549355" "ENSP00000447522;ENSP00000448844;ENSP00000449133;ENSP00000483259;ENSP00000495607;ENSP00000449526" "A0A087WZU1" "PTPRQ" "374462" "protein tyrosine phosphatase receptor type Q" "DFNB84" "Cytosol" "CellAtlas" "ENSG00000139344" "ENST00000266736;ENST00000548310;ENST00000553023;ENST00000549171" "ENSP00000266736;ENSP00000448632;ENSP00000448918" "Q96NU7" "AMDHD1" "144193" "amidohydrolase domain containing 1" "MGC35366" "Cytosol;Nucleus" "CellAtlas" @@ -1430,7 +1423,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000140297" "ENST00000558721;ENST00000560874;ENST00000560580;ENST00000560111;ENST00000559189;ENST00000560585;ENST00000396065;ENST00000559626;ENST00000560210;ENST00000559200" "ENSP00000453453;ENSP00000452741;ENSP00000379377;ENSP00000453928;ENSP00000453774" "O95395" "GCNT3" "9245" "glucosaminyl (N-acetyl) transferase 3, mucin type" "C2/4GnT;C2GnT-M;C2GnT2" "Golgi apparatus" "CellAtlas" "ENSG00000140367" "ENST00000267938;ENST00000569423;ENST00000561723;ENST00000561851;ENST00000562635;ENST00000426727;ENST00000567921;ENST00000563966" "ENSP00000267938;ENSP00000456324;ENSP00000458006;ENSP00000456229;ENSP00000400960;ENSP00000454742" "Q8WVN8" "UBE2Q2" "92912" "ubiquitin conjugating enzyme E2 Q2" "DKFZp762C143" "Cytosol" "SwissProt" "ENSG00000140374" "ENST00000557943;ENST00000433983;ENST00000557975;ENST00000267950;ENST00000565910;ENST00000560179;ENST00000560726;ENST00000559602;ENST00000559973;ENST00000560595;ENST00000560899;ENST00000559075;ENST00000560044;ENST00000560816;ENST00000558803;ENST00000559758;ENST00000560345;ENST00000559386;ENST00000560309;ENST00000561092" "ENSP00000452762;ENSP00000399273;ENSP00000267950;ENSP00000458001;ENSP00000453098;ENSP00000452659;ENSP00000454194;ENSP00000453345;ENSP00000453422;ENSP00000452942;ENSP00000453017;ENSP00000452777;ENSP00000453753" "P13804" "ETFA" "2108" "electron transfer flavoprotein subunit alpha" "EMA;GA2;MADD" "Mitochondria" "SwissProt;CellAtlas" -"ENSG00000140396" "ENST00000452400;ENST00000518287;ENST00000518363;ENST00000521239;ENST00000522054;ENST00000524223;ENST00000519724;ENST00000520416" "ENSP00000399968;ENSP00000430148;ENSP00000429132;ENSP00000430348;ENSP00000430850" "Q15596" "NCOA2" "10499" "nuclear receptor coactivator 2" "bHLHe75;GRIP1;KAT13C;NCoA-2;TIF2" "Nucleus" "SwissProt;CellAtlas" "ENSG00000140400" "ENST00000631426;ENST00000563660;ENST00000562067;ENST00000564929;ENST00000569482;ENST00000565683;ENST00000563622;ENST00000267978;ENST00000561693;ENST00000566099;ENST00000566569;ENST00000563528;ENST00000567163;ENST00000564570;ENST00000564785;ENST00000567360;ENST00000563441;ENST00000563368;ENST00000569176;ENST00000566013;ENST00000563794;ENST00000565953;ENST00000563596;ENST00000566634;ENST00000562461;ENST00000562228;ENST00000563058;ENST00000566253;ENST00000563013;ENST00000568944;ENST00000421803;ENST00000570257;ENST00000565801;ENST00000565784;ENST00000563539;ENST00000565699;ENST00000569355;ENST00000568374;ENST00000565534;ENST00000566256;ENST00000562071;ENST00000561615;ENST00000569069;ENST00000565652;ENST00000618257" "ENSP00000455998;ENSP00000457788;ENSP00000454589;ENSP00000267978;ENSP00000456914;ENSP00000390738;ENSP00000456667;ENSP00000456419;ENSP00000454406;ENSP00000456257;ENSP00000455788;ENSP00000455803;ENSP00000457833;ENSP00000479988" "Q9NTJ4" "MAN2C1" "4123" "mannosidase alpha class 2C member 1" "MANA;MANA1" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000140455" "ENST00000561442;ENST00000560070;ENST00000380324;ENST00000557884;ENST00000558157;ENST00000561326;ENST00000559873;ENST00000559192;ENST00000559771;ENST00000559276;ENST00000558285;ENST00000559257;ENST00000538686;ENST00000559711;ENST00000558925;ENST00000558218;ENST00000561381;ENST00000559718;ENST00000560202;ENST00000540797;ENST00000268049" "ENSP00000453688;ENSP00000453194;ENSP00000369681;ENSP00000454043;ENSP00000452929;ENSP00000453767;ENSP00000453228;ENSP00000453093;ENSP00000454197;ENSP00000453619;ENSP00000452947;ENSP00000445793;ENSP00000453138;ENSP00000453489;ENSP00000445828;ENSP00000268049" "Q9Y6I4" "USP3" "9960" "ubiquitin specific peptidase 3" "" "Nucleus" "SwissProt;CellAtlas" "ENSG00000140459" "ENST00000358632;ENST00000268053;ENST00000498141;ENST00000435365;ENST00000566674;ENST00000450547;ENST00000569662;ENST00000466978;ENST00000416978;ENST00000467407" "ENSP00000351455;ENSP00000268053;ENSP00000391081;ENSP00000456941;ENSP00000402064;ENSP00000456598;ENSP00000388018" "P05108" "CYP11A1" "1583" "cytochrome P450 family 11 subfamily A member 1" "CYP11A;P450SCC" "Inner mitochondria" "SwissProt" @@ -1450,7 +1442,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000140905" "ENST00000315467;ENST00000640150;ENST00000564386;ENST00000639689;ENST00000639169;ENST00000569885;ENST00000639137;ENST00000561801;ENST00000566566;ENST00000564477" "ENSP00000319531;ENSP00000492163;ENSP00000457630;ENSP00000492187;ENSP00000491127;ENSP00000455579;ENSP00000457645;ENSP00000455019;ENSP00000455287" "P23434" "GCSH" "2653" "glycine cleavage system protein H" "" "Mitochondria" "SwissProt" "ENSG00000140990" "ENST00000268668;ENST00000543683;ENST00000565031;ENST00000569148;ENST00000570172" "ENSP00000268668;ENSP00000445086;ENSP00000455348;ENSP00000457908" "O96000" "NDUFB10" "4716" "NADH:ubiquinone oxidoreductase subunit B10" "PDSW" "Inner mitochondria" "SwissProt" "ENSG00000141012" "ENST00000268695;ENST00000562593;ENST00000567525;ENST00000568613;ENST00000564263;ENST00000562931;ENST00000566563;ENST00000562831;ENST00000561812;ENST00000565364;ENST00000567779;ENST00000568311;ENST00000569433" "ENSP00000268695;ENSP00000454484;ENSP00000457921;ENSP00000455174;ENSP00000455006;ENSP00000456884" "P34059" "GALNS" "2588" "galactosamine (N-acetyl)-6-sulfatase" "GALNAC6S;GAS" "Cytosol;Lysosome" "SwissProt;CellAtlas" -"ENSG00000141027" "ENST00000268712;ENST00000464381;ENST00000470782;ENST00000395851;ENST00000580617;ENST00000395849;ENST00000582565;ENST00000579573;ENST00000603989;ENST00000580554;ENST00000579606;ENST00000583234;ENST00000458113;ENST00000472189;ENST00000584872;ENST00000436068;ENST00000395848;ENST00000583226;ENST00000411510;ENST00000582357;ENST00000436828;ENST00000460276;ENST00000585296;ENST00000579974;ENST00000430577;ENST00000466825;ENST00000395857" "ENSP00000268712;ENSP00000379192;ENSP00000379190;ENSP00000461959;ENSP00000474008;ENSP00000463169;ENSP00000462281;ENSP00000389839;ENSP00000379189;ENSP00000407998;ENSP00000462308;ENSP00000387727;ENSP00000462794;ENSP00000410784;ENSP00000379198" "O75376" "NCOR1" "9611" "nuclear receptor corepressor 1" "hCIT529I10;hN-CoR;KIAA1047;MGC104216;N-CoR;PPP1R109;TRAC1" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000141096" "ENST00000268793;ENST00000574342;ENST00000672962" "ENSP00000268793;ENSP00000500237" "Q9H4B8" "DPEP3" "64180" "dipeptidase 3" "" "Cell membrane" "DeepLoc2" "ENSG00000141179" "ENST00000268896;ENST00000576183;ENST00000573500;ENST00000417982;ENST00000325214;ENST00000571489;ENST00000576221;ENST00000572536" "ENSP00000268896;ENSP00000459793;ENSP00000460437;ENSP00000415185;ENSP00000325181;ENSP00000461676" "Q9UKL6" "PCTP" "58488" "phosphatidylcholine transfer protein" "STARD2" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000141279" "ENST00000525007;ENST00000525037;ENST00000677710;ENST00000530173;ENST00000526247;ENST00000677226;ENST00000532729;ENST00000678461;ENST00000322157;ENST00000533573;ENST00000677120;ENST00000678909;ENST00000528751;ENST00000678496;ENST00000678262;ENST00000677370;ENST00000677664;ENST00000527298;ENST00000534691;ENST00000602788;ENST00000527824;ENST00000676492;ENST00000534727;ENST00000534814;ENST00000525401;ENST00000527964;ENST00000530514;ENST00000527360;ENST00000533538;ENST00000525021;ENST00000678902;ENST00000529602;ENST00000534807;ENST00000525048;ENST00000531486;ENST00000528565" "ENSP00000437019;ENSP00000504357;ENSP00000433287;ENSP00000433735;ENSP00000504389;ENSP00000434554;ENSP00000504752;ENSP00000320324;ENSP00000503682;ENSP00000503450;ENSP00000503773;ENSP00000503738;ENSP00000503284;ENSP00000434585;ENSP00000433649;ENSP00000435639;ENSP00000436733;ENSP00000435966;ENSP00000504519;ENSP00000432127;ENSP00000433549" "P55786" "NPEPPS" "9520" "aminopeptidase puromycin sensitive" "MP100;PSA" "Nucleus;Cytosol" "SwissProt;CellAtlas" @@ -1483,7 +1474,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000142230" "ENST00000594144;ENST00000594526;ENST00000597808;ENST00000413379;ENST00000600706;ENST00000598840;ENST00000414294;ENST00000600753;ENST00000270225;ENST00000660039;ENST00000596995;ENST00000664120;ENST00000392776;ENST00000659110" "ENSP00000471010;ENSP00000472389;ENSP00000469938;ENSP00000416557;ENSP00000468931;ENSP00000470741;ENSP00000398818;ENSP00000469978;ENSP00000270225;ENSP00000499743;ENSP00000473037;ENSP00000499784;ENSP00000440818;ENSP00000499761" "Q9UBE0" "SAE1" "10055" "SUMO1 activating enzyme subunit 1" "AOS1;FLJ3091;Sua1" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000142273" "ENST00000341505;ENST00000647358;ENST00000647063" "ENSP00000340250;ENSP00000494162;ENSP00000495258" "Q9ULV8" "CBLC" "23624" "Cbl proto-oncogene C" "CBL-3;CBL-SL;RNF57" "Cytosol;Nucleus" "CellAtlas" "ENSG00000142319" "ENST00000270349;ENST00000512002;ENST00000511750" "ENSP00000270349" "Q01959" "SLC6A3" "6531" "solute carrier family 6 member 3" "DAT;DAT1" "Cell membrane" "DeepLoc2" -"ENSG00000142453" "ENST00000327064;ENST00000588947;ENST00000590699;ENST00000344150;ENST00000586221;ENST00000590039;ENST00000589693;ENST00000586508;ENST00000586298;ENST00000592516" "ENSP00000325690;ENSP00000465417;ENSP00000467420;ENSP00000340934;ENSP00000467746;ENSP00000464852;ENSP00000468319;ENSP00000467761" "Q86X55" "CARM1" "10498" "coactivator associated arginine methyltransferase 1" "PRMT4" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000142494" "ENST00000584348;ENST00000571335;ENST00000436810;ENST00000270570;ENST00000574596;ENST00000576095;ENST00000575023;ENST00000497548;ENST00000395585;ENST00000495425;ENST00000575377;ENST00000573009;ENST00000575362;ENST00000581558" "ENSP00000462630;ENSP00000407155;ENSP00000270570;ENSP00000460164;ENSP00000378951;ENSP00000462225" "Q96FL8" "SLC47A1" "55244" "solute carrier family 47 member 1" "FLJ10847;MATE1" "Cell membrane" "DeepLoc2" "ENSG00000142513" "ENST00000270593" "ENSP00000270593" "Q9BZG2" "ACP4" "93650" "acid phosphatase 4" "ACPT" "Cell membrane;Lysosome" "DeepLoc2" "ENSG00000142583" "ENST00000377424;ENST00000487492;ENST00000377414;ENST00000484798;ENST00000474145;ENST00000479813;ENST00000486632;ENST00000487835;ENST00000464985;ENST00000473209" "ENSP00000366641;ENSP00000366631;ENSP00000467039;ENSP00000464880;ENSP00000468590;ENSP00000465507;ENSP00000465382;ENSP00000467840;ENSP00000465285" "P22732" "SLC2A5" "6518" "solute carrier family 2 member 5" "GLUT5" "Cell membrane" "DeepLoc2" @@ -1508,7 +1498,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000143278" "ENST00000649282;ENST00000367412;ENST00000490002" "ENSP00000497116;ENSP00000356382" "P05160" "F13B" "2165" "coagulation factor XIII B chain" "FXIIIB" "Extracellular" "DeepLoc2" "ENSG00000143315" "ENST00000368090" "ENSP00000357069" "Q9H3S5" "PIGM" "93183" "phosphatidylinositol glycan anchor biosynthesis class M" "GPI-MT-I" "Endoplasmic reticulum" "DeepLoc2" "ENSG00000143324" "ENST00000367590;ENST00000367589" "ENSP00000356562;ENSP00000356561" "Q9UBH6" "XPR1" "9213" "xenotropic and polytropic retrovirus receptor 1" "SYG1;X3;SLC53A1" "" "" -"ENSG00000143344" "ENST00000304685;ENST00000360851" "ENSP00000303192;ENSP00000354097" "Q9NZL6" "RGL1" "23179" "ral guanine nucleotide dissociation stimulator like 1" "RGL" "Golgi apparatus;Nucleus" "CellAtlas" "ENSG00000143363" "ENST00000467771;ENST00000271620;ENST00000462440;ENST00000650332;ENST00000475722;ENST00000450884;ENST00000368937;ENST00000431193;ENST00000368936;ENST00000368935;ENST00000368934" "ENSP00000271620;ENSP00000497847;ENSP00000387696;ENSP00000357933;ENSP00000392632;ENSP00000357932;ENSP00000357931;ENSP00000357930" "Q86TP1" "PRUNE1" "58497" "prune exopolyphosphatase 1" "DRES-17;H-PRUNE;HTCD37;PRUNE" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000143379" "ENST00000525956;ENST00000487584;ENST00000463774;ENST00000271640;ENST00000448029;ENST00000368962;ENST00000534805;ENST00000368969;ENST00000368963;ENST00000459773;ENST00000498193;ENST00000368964;ENST00000423081;ENST00000481219;ENST00000497314;ENST00000528749;ENST00000533529" "ENSP00000435922;ENSP00000271640;ENSP00000409379;ENSP00000357958;ENSP00000436148;ENSP00000357965;ENSP00000357959;ENSP00000432348;ENSP00000357960;ENSP00000407831" "Q15047" "SETDB1" "9869" "SET domain bifurcated histone lysine methyltransferase 1" "ESET;KG1T;KIAA0067;KMT1E;TDRD21" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000143387" "ENST00000678337;ENST00000676716;ENST00000676966;ENST00000443913;ENST00000271651;ENST00000676970;ENST00000679260;ENST00000676680;ENST00000676751;ENST00000677887;ENST00000676824;ENST00000677611;ENST00000678725;ENST00000679148;ENST00000480670;ENST00000679090;ENST00000678275;ENST00000677330;ENST00000679178;ENST00000679171" "ENSP00000504759;ENSP00000504737;ENSP00000503723;ENSP00000405083;ENSP00000271651;ENSP00000503832;ENSP00000504534;ENSP00000503270;ENSP00000502964;ENSP00000503876;ENSP00000504176;ENSP00000504796" "P43235" "CTSK" "1513" "cathepsin K" "CTSO;CTSO2;PKND;PYCD" "Lysosome" "SwissProt" @@ -1808,7 +1797,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000158850" "ENST00000319769;ENST00000470882;ENST00000622395;ENST00000367998;ENST00000486938;ENST00000466504;ENST00000465740;ENST00000493164;ENST00000496313;ENST00000487004;ENST00000460415;ENST00000482288;ENST00000467863" "ENSP00000320965;ENSP00000480428;ENSP00000356977" "O60512" "B4GALT3" "8703" "beta-1,4-galactosyltransferase 3" "beta4Gal-T3" "Golgi apparatus;Cytosol" "SwissProt;CellAtlas" "ENSG00000158864" "ENST00000479948;ENST00000677550;ENST00000676600;ENST00000676653;ENST00000678507;ENST00000496133;ENST00000679064;ENST00000677383;ENST00000677579;ENST00000679215;ENST00000678793;ENST00000677178;ENST00000678052;ENST00000677138;ENST00000677457;ENST00000677613;ENST00000677925;ENST00000676535;ENST00000677547;ENST00000678613;ENST00000677231;ENST00000679282;ENST00000677081;ENST00000677350;ENST00000678605;ENST00000677809;ENST00000678966;ENST00000678911;ENST00000677807;ENST00000677846;ENST00000678492;ENST00000679176;ENST00000367993;ENST00000676991;ENST00000678130;ENST00000496553;ENST00000467295;ENST00000392179;ENST00000678511;ENST00000677453;ENST00000677736;ENST00000678328;ENST00000676583;ENST00000493849;ENST00000677657;ENST00000676726;ENST00000677916;ENST00000677495;ENST00000678484;ENST00000679239;ENST00000677050;ENST00000678850;ENST00000677653;ENST00000678783;ENST00000676871;ENST00000677577;ENST00000678982;ENST00000677063;ENST00000677045;ENST00000679218;ENST00000677837;ENST00000679169;ENST00000678880;ENST00000677745;ENST00000677358;ENST00000677089;ENST00000480762;ENST00000678532;ENST00000677643;ENST00000678648;ENST00000677336;ENST00000677471;ENST00000677948;ENST00000678068;ENST00000676972;ENST00000475570;ENST00000678559;ENST00000676795;ENST00000478866;ENST00000677103;ENST00000679142;ENST00000676770;ENST00000677033;ENST00000679071;ENST00000678356;ENST00000473321;ENST00000465923;ENST00000483804;ENST00000468828;ENST00000492153" "ENSP00000503353;ENSP00000503989;ENSP00000504199;ENSP00000502868;ENSP00000504162;ENSP00000503431;ENSP00000504839;ENSP00000503294;ENSP00000504258;ENSP00000504269;ENSP00000503378;ENSP00000504533;ENSP00000503728;ENSP00000503969;ENSP00000503946;ENSP00000504065;ENSP00000504170;ENSP00000356972;ENSP00000376018;ENSP00000504846;ENSP00000503604;ENSP00000503681;ENSP00000504555;ENSP00000504542;ENSP00000504215;ENSP00000504597;ENSP00000504572;ENSP00000504168;ENSP00000504577;ENSP00000503661;ENSP00000504096;ENSP00000503015;ENSP00000504682;ENSP00000503510;ENSP00000503117;ENSP00000504285;ENSP00000504650;ENSP00000504800" "O75306" "NDUFS2" "4720" "NADH:ubiquinone oxidoreductase core subunit S2" "CI-49" "Inner mitochondria" "SwissProt;CellAtlas" "ENSG00000158865" "ENST00000347898;ENST00000488922;ENST00000564125;ENST00000565769;ENST00000569520;ENST00000568579;ENST00000567758;ENST00000569071;ENST00000565586;ENST00000545376;ENST00000449109;ENST00000424767" "ENSP00000289932;ENSP00000458806;ENSP00000457179;ENSP00000454732;ENSP00000456234;ENSP00000454401;ENSP00000456376;ENSP00000441384;ENSP00000389606;ENSP00000416782" "Q8WWX8" "SLC5A11" "115584" "solute carrier family 5 member 11" "KST1;SGLT6;SMIT2" "Cytosol;Nucleus" "CellAtlas" -"ENSG00000158874" "ENST00000481413;ENST00000367990;ENST00000463812;ENST00000468465;ENST00000481511;ENST00000470459;ENST00000464492;ENST00000491350;ENST00000463273;ENST00000469730" "ENSP00000356969;ENSP00000476890;ENSP00000476662;ENSP00000477054;ENSP00000477031;ENSP00000476911;ENSP00000477353;ENSP00000476740;ENSP00000476605" "P02652" "APOA2" "336" "apolipoprotein A2" "" "Extracellular" "DeepLoc2" "ENSG00000159063" "ENST00000679559;ENST00000680398;ENST00000681221;ENST00000680761;ENST00000525783;ENST00000529139;ENST00000527099;ENST00000681489;ENST00000525870;ENST00000531213;ENST00000681853;ENST00000524925;ENST00000679581;ENST00000680329;ENST00000530910;ENST00000681417;ENST00000681225;ENST00000681765;ENST00000530608;ENST00000680063;ENST00000679986;ENST00000681699;ENST00000680459;ENST00000679685;ENST00000681384;ENST00000679874;ENST00000679444;ENST00000680142;ENST00000681723;ENST00000680797;ENST00000680256;ENST00000679697;ENST00000680580;ENST00000526849;ENST00000299626;ENST00000680467;ENST00000679497;ENST00000681351;ENST00000681575;ENST00000526737;ENST00000680223;ENST00000680866;ENST00000376156;ENST00000680499;ENST00000680829;ENST00000680101;ENST00000679648;ENST00000532306;ENST00000680996;ENST00000532440;ENST00000525761;ENST00000680399;ENST00000679539;ENST00000615266;ENST00000681957;ENST00000532552;ENST00000680643;ENST00000530454;ENST00000525755;ENST00000532050;ENST00000680650;ENST00000526928" "ENSP00000505433;ENSP00000506189;ENSP00000505136;ENSP00000506421;ENSP00000434066;ENSP00000432953;ENSP00000436064;ENSP00000505200;ENSP00000435417;ENSP00000506215;ENSP00000437033;ENSP00000505965;ENSP00000505016;ENSP00000505811;ENSP00000432381;ENSP00000504928;ENSP00000505614;ENSP00000504969;ENSP00000506617;ENSP00000505698;ENSP00000506249;ENSP00000506314;ENSP00000506099;ENSP00000506059;ENSP00000506717;ENSP00000505074;ENSP00000505696;ENSP00000506170;ENSP00000434388;ENSP00000299626;ENSP00000505609;ENSP00000505407;ENSP00000506652;ENSP00000505743;ENSP00000436366;ENSP00000505023;ENSP00000505649;ENSP00000365326;ENSP00000506092;ENSP00000506408;ENSP00000504917;ENSP00000505726;ENSP00000435626;ENSP00000505468;ENSP00000433429;ENSP00000431357;ENSP00000505984;ENSP00000504910;ENSP00000480742;ENSP00000506056;ENSP00000505207;ENSP00000434660;ENSP00000435467;ENSP00000437199" "Q9BVK2" "ALG8" "79053" "ALG8 alpha-1,3-glucosyltransferase" "MGC2840" "Endoplasmic reticulum;Nucleus" "SwissProt;CellAtlas" "ENSG00000159082" "ENST00000438952;ENST00000630077;ENST00000674204;ENST00000674351;ENST00000674308;ENST00000418301;ENST00000467445;ENST00000464778;ENST00000429236;ENST00000456084;ENST00000382499;ENST00000433931;ENST00000357345;ENST00000382491" "ENSP00000388869;ENSP00000487560;ENSP00000501504;ENSP00000501530;ENSP00000501426;ENSP00000387868;ENSP00000413649;ENSP00000412707;ENSP00000371939;ENSP00000409667;ENSP00000349903;ENSP00000371931" "O43426" "SYNJ1" "8867" "synaptojanin 1" "INPP5G;PARK20" "Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000159131" "ENST00000381815;ENST00000381831;ENST00000381839;ENST00000424203;ENST00000482663;ENST00000487155;ENST00000460305;ENST00000467575;ENST00000361093;ENST00000366093;ENST00000466882;ENST00000497313;ENST00000430874;ENST00000426819;ENST00000476524;ENST00000488791;ENST00000438059;ENST00000441403" "ENSP00000371236;ENSP00000371253;ENSP00000371261;ENSP00000390003;ENSP00000354388;ENSP00000409771;ENSP00000413040;ENSP00000398631;ENSP00000413803;ENSP00000407783" "P22102" "GART" "2618" "phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" "GARS-AIRS-GART;PGFT;PRGS" "Mitochondria;Cytosol" "CellAtlas" @@ -2055,7 +2043,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000166800" "ENST00000615355;ENST00000396213;ENST00000280706" "ENSP00000478764;ENSP00000379516;ENSP00000280706" "Q6ZMR3" "LDHAL6A" "160287" "lactate dehydrogenase A like 6A" "LDH6A;MGC23940" "Cytosol" "DeepLoc2" "ENSG00000166816" "ENST00000300051;ENST00000450168;ENST00000569876;ENST00000568164" "ENSP00000300051;ENSP00000417011;ENSP00000454260" "Q86WU2" "LDHD" "197257" "lactate dehydrogenase D" "" "Mitochondria;Cytosol" "SwissProt;CellAtlas" "ENSG00000166819" "ENST00000560330;ENST00000300055;ENST00000430628;ENST00000531697" "ENSP00000453426;ENSP00000300055;ENSP00000402167" "O60240" "PLIN1" "5346" "perilipin 1" "PLIN" "Endoplasmic reticulum;Peroxisome" "SwissProt;CellAtlas" -"ENSG00000166821" "ENST00000557982;ENST00000561224;ENST00000300056;ENST00000561257;ENST00000559170" "ENSP00000453552;ENSP00000300056;ENSP00000453492;ENSP00000453878" "O75192" "PEX11A" "8800" "peroxisomal biogenesis factor 11 alpha" "MGC119947;MGC138534;PEX11-ALPHA" "Peroxisome" "SwissProt" "ENSG00000166825" "ENST00000679248;ENST00000300060;ENST00000560137;ENST00000559874;ENST00000558740;ENST00000559761;ENST00000558177;ENST00000560030;ENST00000559887;ENST00000560028" "ENSP00000502886;ENSP00000300060;ENSP00000453413;ENSP00000452934;ENSP00000453545;ENSP00000453405" "P15144" "ANPEP" "290" "alanyl aminopeptidase, membrane" "CD13;gp150;LAP1;p150;PEPN" "Cell membrane" "DeepLoc2" "ENSG00000166840" "ENST00000534674;ENST00000524629;ENST00000525608;ENST00000526351;ENST00000317391;ENST00000533864;ENST00000534612;ENST00000524403;ENST00000532726;ENST00000527708;ENST00000300079;ENST00000530774;ENST00000534241;ENST00000530240;ENST00000531245;ENST00000524881;ENST00000534119;ENST00000534063;ENST00000612196" "ENSP00000433716;ENSP00000434652;ENSP00000322223;ENSP00000431640;ENSP00000436116;ENSP00000434757;ENSP00000300079;ENSP00000434661;ENSP00000437155;ENSP00000432225;ENSP00000479741" "Q969I3" "GLYATL1" "92292" "glycine-N-acyltransferase like 1" "FLJ34646;MGC15397" "Cytosol;Golgi apparatus" "CellAtlas" "ENSG00000166908" "ENST00000422156;ENST00000354947;ENST00000540759;ENST00000551772;ENST00000550465;ENST00000550360;ENST00000550095;ENST00000548264" "ENSP00000412035;ENSP00000347032;ENSP00000439878;ENSP00000450197;ENSP00000447390;ENSP00000449335;ENSP00000448042;ENSP00000449538" "Q8TBX8" "PIP4K2C" "79837" "phosphatidylinositol-5-phosphate 4-kinase type 2 gamma" "FLJ22055;PIP5K2C" "Endoplasmic reticulum;Nucleus;Cytosol" "SwissProt;CellAtlas" @@ -2099,7 +2086,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000167748" "ENST00000301420;ENST00000593325;ENST00000593859;ENST00000596300" "ENSP00000301420;ENSP00000472939" "P06870" "KLK1" "3816" "kallikrein 1" "Klk6" "Extracellular" "DeepLoc2" "ENSG00000167751" "ENST00000593493;ENST00000595375;ENST00000597509;ENST00000596950;ENST00000325321;ENST00000600690;ENST00000599280;ENST00000594174;ENST00000597727;ENST00000595316;ENST00000599121;ENST00000600755;ENST00000600866;ENST00000358049;ENST00000597439;ENST00000601743;ENST00000599568;ENST00000595173;ENST00000601114;ENST00000595050;ENST00000597911;ENST00000597461;ENST00000391810" "ENSP00000472852;ENSP00000313581;ENSP00000469318;ENSP00000472095;ENSP00000471014;ENSP00000469770;ENSP00000472499;ENSP00000350748;ENSP00000471214;ENSP00000471323;ENSP00000471725;ENSP00000471321;ENSP00000375686" "P20151" "KLK2" "3817" "kallikrein related peptidase 2" "" "Extracellular" "DeepLoc2" "ENSG00000167769" "ENST00000301452" "ENSP00000301452" "Q8TDN7" "ACER1" "125981" "alkaline ceramidase 1" "ASAH3" "Endoplasmic reticulum" "SwissProt" -"ENSG00000167772" "ENST00000601886;ENST00000599192;ENST00000597137;ENST00000601770;ENST00000301455;ENST00000595079;ENST00000598255;ENST00000594348;ENST00000393962;ENST00000593998;ENST00000594875" "ENSP00000470307;ENSP00000473090;ENSP00000471345;ENSP00000301455;ENSP00000473025;ENSP00000377534;ENSP00000472551;ENSP00000472869" "Q9BY76" "ANGPTL4" "51129" "angiopoietin like 4" "ARP4;FIAF;HFARP;NL2;PGAR;pp1158" "Nucleus" "CellAtlas" "ENSG00000167780" "ENST00000551896;ENST00000301466;ENST00000542365" "ENSP00000450120;ENSP00000301466;ENSP00000442234" "O75908" "SOAT2" "8435" "sterol O-acyltransferase 2" "ACAT2" "Endoplasmic reticulum" "SwissProt" "ENSG00000167792" "ENST00000647561;ENST00000532303;ENST00000532244;ENST00000528328;ENST00000322776;ENST00000529927;ENST00000524876;ENST00000524838;ENST00000532343;ENST00000415352;ENST00000528548;ENST00000532260;ENST00000530014;ENST00000530103;ENST00000525086;ENST00000534139;ENST00000533075;ENST00000529867;ENST00000526138;ENST00000530638;ENST00000528314;ENST00000528377;ENST00000526770;ENST00000526169;ENST00000533919;ENST00000527355;ENST00000527923;ENST00000531250;ENST00000534352" "ENSP00000497587;ENSP00000432015;ENSP00000435202;ENSP00000436906;ENSP00000322450;ENSP00000436766;ENSP00000431751;ENSP00000395368;ENSP00000434575;ENSP00000437267;ENSP00000434438;ENSP00000436936;ENSP00000434581;ENSP00000435199;ENSP00000432637" "P49821" "NDUFV1" "4723" "NADH:ubiquinone oxidoreductase core subunit V1" "CI-51K" "Cytosol;Inner mitochondria" "SwissProt;CellAtlas" "ENSG00000167815" "ENST00000334482;ENST00000466174;ENST00000301522;ENST00000498785;ENST00000478908;ENST00000477555" "ENSP00000334063;ENSP00000301522" "P32119" "PRDX2" "7001" "peroxiredoxin 2" "MGC4104;NKEFB;PRP;PRX2;PRXII;TDPX1;TSA" "Cytosol" "SwissProt" @@ -2152,7 +2138,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000169255" "ENST00000392781;ENST00000320474;ENST00000392779;ENST00000651430;ENST00000650695;ENST00000651801;ENST00000651379;ENST00000652111;ENST00000651460;ENST00000651686;ENST00000651972;ENST00000651953;ENST00000651292;ENST00000651380;ENST00000651689;ENST00000652059;ENST00000652730;ENST00000651791;ENST00000651117;ENST00000651254;ENST00000651178;ENST00000651916;ENST00000651282;ENST00000652377;ENST00000652143;ENST00000650733;ENST00000417187;ENST00000652134;ENST00000652593;ENST00000496295;ENST00000473285;ENST00000651509;ENST00000651305;ENST00000652669;ENST00000652596;ENST00000651147;ENST00000651422;ENST00000494818;ENST00000476999;ENST00000494173;ENST00000652032;ENST00000488170;ENST00000652309;ENST00000468268;ENST00000492353;ENST00000473142;ENST00000498216;ENST00000484127;ENST00000460353;ENST00000478383;ENST00000497487" "ENSP00000376532;ENSP00000323479;ENSP00000376530;ENSP00000499079;ENSP00000498902;ENSP00000498243;ENSP00000498978;ENSP00000498689;ENSP00000498369;ENSP00000498346;ENSP00000498907;ENSP00000498633;ENSP00000498542;ENSP00000499072;ENSP00000499010;ENSP00000498743;ENSP00000498660;ENSP00000499180;ENSP00000498854;ENSP00000498553;ENSP00000498982;ENSP00000498487;ENSP00000498435;ENSP00000498481;ENSP00000498655;ENSP00000499186;ENSP00000407027;ENSP00000498331;ENSP00000418226;ENSP00000499003;ENSP00000498427;ENSP00000498696;ENSP00000498810;ENSP00000498478;ENSP00000498378;ENSP00000498840;ENSP00000419127;ENSP00000498901;ENSP00000420163;ENSP00000498765;ENSP00000419476;ENSP00000418567;ENSP00000420604;ENSP00000417643;ENSP00000420059;ENSP00000417053" "O75752" "B3GALNT1" "8706" "beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)" "B3GALT3;beta3Gal-T3;galT3;GLOB;P1" "Golgi apparatus" "SwissProt" "ENSG00000169299" "ENST00000381967;ENST00000515668;ENST00000505986;ENST00000512556;ENST00000510084;ENST00000625312" "ENSP00000371393;ENSP00000426738;ENSP00000423269;ENSP00000425733;ENSP00000422785;ENSP00000485904" "Q96G03" "PGM2" "55276" "phosphoglucomutase 2" "FLJ10983" "Cytosol" "SwissProt" "ENSG00000169359" "ENST00000643144;ENST00000359479;ENST00000468581;ENST00000646424;ENST00000644094;ENST00000642438;ENST00000644855;ENST00000475842;ENST00000496772;ENST00000460729" "ENSP00000496241;ENSP00000352456;ENSP00000418847;ENSP00000494846;ENSP00000494476;ENSP00000495971;ENSP00000493564;ENSP00000419066;ENSP00000419165" "O00400" "SLC33A1" "9197" "solute carrier family 33 member 1" "ACATN;AT-1;AT1;SPG42" "Endoplasmic reticulum;Cytosol" "SwissProt;CellAtlas" -"ENSG00000169375" "ENST00000394947;ENST00000360439;ENST00000394949;ENST00000566640;ENST00000570124;ENST00000570021;ENST00000564778;ENST00000562776;ENST00000568431;ENST00000567289;ENST00000570115;ENST00000568309;ENST00000568190;ENST00000568919;ENST00000565264" "ENSP00000378402;ENSP00000353622;ENSP00000378403;ENSP00000455204;ENSP00000455072;ENSP00000454750;ENSP00000455834;ENSP00000455662;ENSP00000455644;ENSP00000456997;ENSP00000454296" "Q96ST3" "SIN3A" "25942" "SIN3 transcription regulator family member A" "DKFZP434K2235;KIAA0700" "Nucleus" "SwissProt;CellAtlas" "ENSG00000169418" "ENST00000368680;ENST00000413826;ENST00000368677" "ENSP00000357669" "P16066" "NPR1" "4881" "natriuretic peptide receptor 1" "ANPa;ANPRA;GUCY2A;NPRA" "Nucleus" "CellAtlas" "ENSG00000169660" "ENST00000337014;ENST00000644886;ENST00000327949;ENST00000583978;ENST00000580235;ENST00000578775;ENST00000582315;ENST00000577944;ENST00000581482;ENST00000644009;ENST00000578632;ENST00000582429;ENST00000578130;ENST00000585077;ENST00000578616;ENST00000583354;ENST00000582131" "ENSP00000337854;ENSP00000332634;ENSP00000462856;ENSP00000462303;ENSP00000462923;ENSP00000463129;ENSP00000464497;ENSP00000496193;ENSP00000463625;ENSP00000464912;ENSP00000462000;ENSP00000463241;ENSP00000465465" "Q8WVB3" "HEXD" "284004" "hexosaminidase D" "FLJ23825;HEXDC" "Nucleus;Mitochondria;Cytosol" "SwissProt;CellAtlas" "ENSG00000169692" "ENST00000371694;ENST00000371696;ENST00000538402;ENST00000472820;ENST00000470861" "ENSP00000360759;ENSP00000360761;ENSP00000438919" "O15120" "AGPAT2" "10555" "1-acylglycerol-3-phosphate O-acyltransferase 2" "BSCL;LPAAT-beta" "Endoplasmic reticulum" "SwissProt" @@ -2181,7 +2166,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000170430" "ENST00000482653;ENST00000651593;ENST00000482547;ENST00000462672;ENST00000306010" "ENSP00000498729;ENSP00000302111" "P16455" "MGMT" "4255" "O-6-methylguanine-DNA methyltransferase" "" "Nucleus" "SwissProt;CellAtlas" "ENSG00000170445" "ENST00000675898;ENST00000675355;ENST00000675967;ENST00000675763;ENST00000675698;ENST00000676327;ENST00000675094;ENST00000506579;ENST00000675851;ENST00000675366;ENST00000674523;ENST00000431330;ENST00000457527;ENST00000675827;ENST00000504156;ENST00000504366;ENST00000307633;ENST00000509087;ENST00000438307;ENST00000645491;ENST00000512396;ENST00000675204;ENST00000646229;ENST00000643686;ENST00000507746;ENST00000415192;ENST00000518126;ENST00000502888;ENST00000674721;ENST00000674819" "ENSP00000501581;ENSP00000502594;ENSP00000502624;ENSP00000501747;ENSP00000501816;ENSP00000393244;ENSP00000387893;ENSP00000501900;ENSP00000425634;ENSP00000304668;ENSP00000502781;ENSP00000411511;ENSP00000494297;ENSP00000421576;ENSP00000501643;ENSP00000495358;ENSP00000493611;ENSP00000425889;ENSP00000411085" "P12081" "HARS1" "3035" "histidyl-tRNA synthetase 1" "HARS;HisRS;USH3B" "Cytosol" "SwissProt;CellAtlas" "ENSG00000170482" "ENST00000353963;ENST00000348729;ENST00000504513;ENST00000506512;ENST00000503919;ENST00000502863;ENST00000508270" "ENSP00000302851;ENSP00000302701;ENSP00000422688;ENSP00000427271" "Q9UHI7" "SLC23A1" "9963" "solute carrier family 23 member 1" "SLC23A2;SVCT1;YSPL3" "Cell membrane;Lysosome" "DeepLoc2" -"ENSG00000170485" "ENST00000335681;ENST00000427413;ENST00000486017;ENST00000448812;ENST00000451740;ENST00000492373;ENST00000474550;ENST00000471974;ENST00000450763;ENST00000433408;ENST00000495559;ENST00000490052" "ENSP00000338283;ENSP00000397595;ENSP00000388528;ENSP00000395265;ENSP00000392125;ENSP00000393396" "Q99743" "NPAS2" "4862" "neuronal PAS domain protein 2" "bHLHe9;MOP4;PASD4" "Nucleus" "SwissProt;CellAtlas" "ENSG00000170502" "ENST00000302174;ENST00000512216;ENST00000514345;ENST00000473942;ENST00000514227;ENST00000440591;ENST00000502933;ENST00000515371" "ENSP00000303575;ENSP00000424702;ENSP00000421811;ENSP00000410270;ENSP00000422232" "Q9BW91" "NUDT9" "53343" "nudix hydrolase 9" "MGC3037" "Mitochondria;Nucleus" "CellAtlas" "ENSG00000170516" "ENST00000396533;ENST00000355591;ENST00000505102;ENST00000543208" "ENSP00000379784;ENSP00000347799;ENSP00000423519;ENSP00000437439" "Q8TF08" "COX7B2" "170712" "cytochrome c oxidase subunit 7B2" "" "Mitochondria" "DeepLoc2" "ENSG00000170522" "ENST00000302274;ENST00000394607;ENST00000514184;ENST00000507451;ENST00000506625;ENST00000506461;ENST00000503885;ENST00000513003" "ENSP00000304736;ENSP00000378105;ENSP00000424023;ENSP00000425488;ENSP00000426086" "Q9H5J4" "ELOVL6" "79071" "ELOVL fatty acid elongase 6" "FLJ23378;LCE;MGC5487" "Endoplasmic reticulum" "SwissProt" @@ -2217,7 +2201,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000171503" "ENST00000512251;ENST00000682345;ENST00000436096;ENST00000684296;ENST00000682734;ENST00000682601;ENST00000684622;ENST00000684552;ENST00000683483;ENST00000684641;ENST00000682456;ENST00000684675;ENST00000684627;ENST00000683478;ENST00000511912;ENST00000683079;ENST00000684505;ENST00000683305;ENST00000684036;ENST00000683751;ENST00000507475;ENST00000510353;ENST00000683004;ENST00000684611;ENST00000683448;ENST00000684129;ENST00000683750;ENST00000307738;ENST00000682409;ENST00000683081;ENST00000506422;ENST00000682452;ENST00000682820;ENST00000683799;ENST00000684749;ENST00000682178;ENST00000682910;ENST00000681978;ENST00000684209;ENST00000514148;ENST00000683123;ENST00000682613;ENST00000682566;ENST00000683181;ENST00000683209;ENST00000683622" "ENSP00000508122;ENSP00000507740;ENSP00000507860;ENSP00000507546;ENSP00000506899;ENSP00000507719;ENSP00000507642;ENSP00000508240;ENSP00000506934;ENSP00000507471;ENSP00000507793;ENSP00000426638;ENSP00000507296;ENSP00000508237;ENSP00000508043;ENSP00000507276;ENSP00000506944;ENSP00000506936;ENSP00000506931;ENSP00000507174;ENSP00000303552;ENSP00000507722" "Q16134" "ETFDH" "2110" "electron transfer flavoprotein dehydrogenase" "ETFQO" "Inner mitochondria" "SwissProt" "ENSG00000171560" "ENST00000651975;ENST00000403106;ENST00000622532" "ENSP00000498441;ENSP00000385981;ENSP00000478487" "P02671" "FGA" "2243" "fibrinogen alpha chain" "" "Endoplasmic reticulum" "CellAtlas" "ENSG00000171608" "ENST00000377346;ENST00000484851;ENST00000361110;ENST00000481137;ENST00000479223;ENST00000536656;ENST00000628140;ENST00000543390" "ENSP00000366563;ENSP00000354410;ENSP00000446444;ENSP00000486826;ENSP00000443811" "O00329" "PIK3CD" "5293" "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" "p110D" "Cytosol" "SwissProt" -"ENSG00000171720" "ENST00000469550;ENST00000305264;ENST00000469207;ENST00000459727;ENST00000491581;ENST00000486618;ENST00000467533;ENST00000492407;ENST00000475549;ENST00000523088;ENST00000519474;ENST00000476739;ENST00000495485;ENST00000490808;ENST00000471968;ENST00000492506" "ENSP00000302967;ENSP00000429099;ENSP00000430782" "O15379" "HDAC3" "8841" "histone deacetylase 3" "HD3;KDAC3;RPD3;RPD3-2" "Golgi apparatus;Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000171723" "ENST00000315266;ENST00000478722;ENST00000459628;ENST00000543237;ENST00000555668;ENST00000556633;ENST00000557654;ENST00000553936;ENST00000556020;ENST00000544752;ENST00000555456;ENST00000556501;ENST00000555527;ENST00000555503;ENST00000557678;ENST00000556240" "ENSP00000312771;ENSP00000417901;ENSP00000452220;ENSP00000438404;ENSP00000451935;ENSP00000451056;ENSP00000451790;ENSP00000451725;ENSP00000450706;ENSP00000452009;ENSP00000450442" "Q9NQX3" "GPHN" "10243" "gephyrin" "KIAA1385" "Cytosol" "SwissProt;CellAtlas" "ENSG00000171759" "ENST00000553106;ENST00000307000;ENST00000551114;ENST00000635528;ENST00000635477;ENST00000549247;ENST00000549111;ENST00000551988;ENST00000550978;ENST00000551337;ENST00000548928;ENST00000546844;ENST00000548677;ENST00000635500;ENST00000547319;ENST00000546708;ENST00000552251;ENST00000550405" "ENSP00000448059;ENSP00000303500;ENSP00000489230;ENSP00000489016;ENSP00000447620;ENSP00000446658" "P00439" "PAH" "5053" "phenylalanine hydroxylase" "PH" "Endoplasmic reticulum" "CellAtlas" "ENSG00000171766" "ENST00000396659;ENST00000558362;ENST00000676090;ENST00000675323;ENST00000675158;ENST00000675974;ENST00000674905;ENST00000675701;ENST00000558336;ENST00000561376;ENST00000558916;ENST00000558163;ENST00000558537;ENST00000561148;ENST00000559885;ENST00000558118;ENST00000560538;ENST00000458245;ENST00000527933" "ENSP00000379895;ENSP00000501630;ENSP00000502445;ENSP00000501737;ENSP00000502176;ENSP00000502671;ENSP00000454008;ENSP00000453781;ENSP00000453151;ENSP00000453860;ENSP00000453087;ENSP00000452971" "P50440" "GATM" "2628" "glycine amidinotransferase" "AGAT" "Cytosol;Inner mitochondria" "SwissProt;CellAtlas" @@ -2369,7 +2352,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000177414" "ENST00000371077;ENST00000611228;ENST00000371076;ENST00000608020;ENST00000464349;ENST00000608956" "ENSP00000360117;ENSP00000481174;ENSP00000360116;ENSP00000477356;ENSP00000476556" "Q5VVX9" "UBE2U" "148581" "ubiquitin conjugating enzyme E2 U" "MGC35130" "Cytosol" "DeepLoc2" "ENSG00000177465" "ENST00000326303" "ENSP00000323071" "Q8N9L9" "ACOT4" "122970" "acyl-CoA thioesterase 4" "FLJ31235;PTE-Ib;PTE2B" "Peroxisome" "SwissProt" "ENSG00000177542" "ENST00000320230;ENST00000628067;ENST00000531214;ENST00000481290;ENST00000627843;ENST00000630809;ENST00000531437;ENST00000625419;ENST00000532484;ENST00000528606;ENST00000529351;ENST00000533385;ENST00000531534;ENST00000531514;ENST00000527723;ENST00000526152;ENST00000527734;ENST00000625752;ENST00000456706;ENST00000528936;ENST00000524891;ENST00000629634;ENST00000625316;ENST00000529066;ENST00000532361;ENST00000527127;ENST00000525010;ENST00000532459;ENST00000525644;ENST00000629602;ENST00000530360" "ENSP00000322020;ENSP00000486058;ENSP00000437236;ENSP00000431829;ENSP00000486512;ENSP00000435862;ENSP00000485719;ENSP00000431466;ENSP00000437045;ENSP00000432222;ENSP00000434287;ENSP00000435402;ENSP00000433780;ENSP00000434479;ENSP00000436745;ENSP00000433655;ENSP00000487237;ENSP00000392749;ENSP00000432817;ENSP00000486434;ENSP00000433028;ENSP00000434850" "Q9H936" "SLC25A22" "79751" "solute carrier family 25 member 22" "EIEE3;FLJ13044;GC1;NET44" "Nucleus;Inner mitochondria" "SwissProt;CellAtlas" -"ENSG00000177565" "ENST00000636864;ENST00000430069;ENST00000637659;ENST00000474363;ENST00000673974;ENST00000631253;ENST00000457928;ENST00000352800;ENST00000422442;ENST00000626758;ENST00000638074;ENST00000636348;ENST00000635757;ENST00000637681;ENST00000428970;ENST00000424913;ENST00000437738;ENST00000431421;ENST00000635794;ENST00000630796;ENST00000450267;ENST00000630833;ENST00000431674;ENST00000422066;ENST00000443315;ENST00000627825;ENST00000427349;ENST00000413084;ENST00000637137;ENST00000491623;ENST00000637544;ENST00000636478;ENST00000637755;ENST00000636187;ENST00000636912;ENST00000637123" "ENSP00000405574;ENSP00000490514;ENSP00000501274;ENSP00000486324;ENSP00000413251;ENSP00000263964;ENSP00000387849;ENSP00000486622;ENSP00000391559;ENSP00000404863;ENSP00000392180;ENSP00000402402;ENSP00000490246;ENSP00000486235;ENSP00000406297;ENSP00000486082;ENSP00000397450;ENSP00000398477;ENSP00000396120;ENSP00000401044;ENSP00000415506" "Q9BZK7" "TBL1XR1" "79718" "TBL1X receptor 1" "C21;DC42;FLJ12894;IRA1;TBLR1" "Nucleus" "SwissProt;CellAtlas" "ENSG00000177628" "ENST00000368373;ENST00000327247;ENST00000464536;ENST00000427500;ENST00000428024;ENST00000478472;ENST00000484489;ENST00000491081;ENST00000497670;ENST00000460156;ENST00000493842;ENST00000473570;ENST00000467918;ENST00000470104" "ENSP00000357357;ENSP00000314508;ENSP00000402577;ENSP00000397986" "P04062" "GBA" "2629" "glucosylceramidase beta" "GBA1;GLUC" "Lysosome" "SwissProt" "ENSG00000177646" "ENST00000505602;ENST00000679613;ENST00000681367;ENST00000681583;ENST00000514643;ENST00000681784;ENST00000681319;ENST00000681585;ENST00000511325;ENST00000680636;ENST00000512801;ENST00000308982;ENST00000505192;ENST00000511227;ENST00000681552;ENST00000679399;ENST00000515429;ENST00000514336;ENST00000679990;ENST00000681886;ENST00000679431;ENST00000680764;ENST00000505867;ENST00000681589;ENST00000680744;ENST00000679824;ENST00000679715;ENST00000511526;ENST00000508971;ENST00000680638" "ENSP00000504971;ENSP00000505309;ENSP00000506340;ENSP00000422020;ENSP00000506316;ENSP00000504886;ENSP00000427283;ENSP00000312618;ENSP00000426277;ENSP00000425226;ENSP00000505699;ENSP00000505434;ENSP00000426189;ENSP00000423758;ENSP00000506500;ENSP00000506440;ENSP00000505126;ENSP00000425346;ENSP00000505243;ENSP00000505516;ENSP00000506228;ENSP00000422683" "Q9H845" "ACAD9" "28976" "acyl-CoA dehydrogenase family member 9" "MGC14452;NPD002" "Inner mitochondria" "SwissProt;CellAtlas" "ENSG00000177666" "ENST00000336615;ENST00000525250;ENST00000534561;ENST00000531923;ENST00000529255;ENST00000526083" "ENSP00000337701" "Q96AD5" "PNPLA2" "57104" "patatin like phospholipase domain containing 2" "ATGL;desnutrin;FP17548;iPLA2zeta;TTS-2.2" "Nucleus;Cytosol" "SwissProt;CellAtlas" @@ -2540,7 +2522,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000186281" "ENST00000486463;ENST00000359548;ENST00000434632;ENST00000453542;ENST00000484440;ENST00000471757;ENST00000482704;ENST00000439254;ENST00000468438;ENST00000488515" "ENSP00000352547;ENSP00000389395;ENSP00000393770;ENSP00000401334" "Q6NUI2" "GPAT2" "150763" "glycerol-3-phosphate acyltransferase 2, mitochondrial" "CT123" "Mitochondria" "CellAtlas" "ENSG00000186334" "ENST00000335230;ENST00000423071;ENST00000377713" "ENSP00000334750;ENSP00000366942" "Q495N2" "SLC36A3" "285641" "solute carrier family 36 member 3" "PAT3;TRAMD2;tramdorin2" "Cell membrane;Lysosome" "DeepLoc2" "ENSG00000186335" "ENST00000335244;ENST00000518617;ENST00000518280;ENST00000521967;ENST00000523044;ENST00000522829" "ENSP00000334223;ENSP00000430149;ENSP00000428453;ENSP00000430535;ENSP00000428634" "Q495M3" "SLC36A2" "153201" "solute carrier family 36 member 2" "PAT2;TRAMD1;tramdorin" "Endoplasmic reticulum" "SwissProt" -"ENSG00000186350" "ENST00000484822;ENST00000481739;ENST00000356384;ENST00000672570;ENST00000649020" "ENSP00000419692;ENSP00000500402;ENSP00000497073" "P19793" "RXRA" "6256" "retinoid X receptor alpha" "NR2B1" "Golgi apparatus;Mitochondria;Nucleus;Cytosol" "SwissProt;CellAtlas" "ENSG00000186377" "ENST00000371901;ENST00000466294" "ENSP00000360968" "Q8N118" "CYP4X1" "260293" "cytochrome P450 family 4 subfamily X member 1" "MGC40051" "Endoplasmic reticulum" "DeepLoc2" "ENSG00000186526" "ENST00000617645;ENST00000441682;ENST00000325723;ENST00000590209;ENST00000622291;ENST00000612078;ENST00000587680;ENST00000589927;ENST00000585349;ENST00000590745;ENST00000589778;ENST00000589722" "ENSP00000478555;ENSP00000479430;ENSP00000477567;ENSP00000482692" "P98187" "CYP4F8" "11283" "cytochrome P450 family 4 subfamily F member 8" "" "Endoplasmic reticulum" "SwissProt" "ENSG00000186529" "ENST00000592279;ENST00000586182;ENST00000591058;ENST00000221307;ENST00000587360;ENST00000585846;ENST00000609670;ENST00000592424;ENST00000588886" "ENSP00000466395;ENSP00000466988;ENSP00000221307;ENSP00000465394;ENSP00000468105;ENSP00000476546" "Q08477" "CYP4F3" "4051" "cytochrome P450 family 4 subfamily F member 3" "CYP4F;LTB4H" "Endoplasmic reticulum" "SwissProt" @@ -2548,7 +2529,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000186642" "ENST00000334456;ENST00000376450;ENST00000539367;ENST00000544570;ENST00000418754;ENST00000540345;ENST00000536918;ENST00000420501;ENST00000544239;ENST00000441209;ENST00000542223;ENST00000475807;ENST00000538299;ENST00000536308;ENST00000543750;ENST00000543575;ENST00000490749;ENST00000541998;ENST00000538749;ENST00000537631;ENST00000540380;ENST00000485058;ENST00000535701;ENST00000542969;ENST00000546038;ENST00000536458;ENST00000444035" "ENSP00000334910;ENSP00000365633;ENSP00000445443;ENSP00000442256;ENSP00000410310;ENSP00000446399;ENSP00000388997;ENSP00000392457;ENSP00000440834;ENSP00000439077;ENSP00000441322;ENSP00000438559;ENSP00000438008;ENSP00000442797;ENSP00000438868;ENSP00000439683;ENSP00000443737;ENSP00000439302;ENSP00000443232;ENSP00000438295;ENSP00000445750;ENSP00000411657" "O00408" "PDE2A" "5138" "phosphodiesterase 2A" "" "Mitochondria;Cytosol;Inner mitochondria" "SwissProt;CellAtlas" "ENSG00000186792" "ENST00000359051;ENST00000621157;ENST00000336307;ENST00000415204;ENST00000450982;ENST00000513170;ENST00000435141" "ENSP00000351946;ENSP00000479935;ENSP00000337425;ENSP00000401092;ENSP00000391922;ENSP00000424633;ENSP00000391663" "O43820" "HYAL3" "8372" "hyaluronidase 3" "LUCA-3;LUCA14;Minna14" "Cytosol;Lysosome;Endoplasmic reticulum" "SwissProt" "ENSG00000186908" "ENST00000426126;ENST00000546778;ENST00000552453;ENST00000547620;ENST00000550876;ENST00000551407;ENST00000547604;ENST00000550163;ENST00000549682;ENST00000549944;ENST00000549010;ENST00000550789;ENST00000552693;ENST00000553091;ENST00000550244;ENST00000547673" "ENSP00000403397;ENSP00000447871;ENSP00000449551;ENSP00000446954;ENSP00000449734;ENSP00000447934;ENSP00000449728;ENSP00000449836;ENSP00000450295;ENSP00000448757" "Q8IUH5" "ZDHHC17" "23390" "zinc finger DHHC-type palmitoyltransferase 17" "HIP14;HYPH;KIAA0946" "Golgi apparatus;Cytosol" "SwissProt;CellAtlas" -"ENSG00000186951" "ENST00000440343;ENST00000415785;ENST00000420804;ENST00000460086;ENST00000407236;ENST00000496865;ENST00000624793;ENST00000484619;ENST00000481567;ENST00000402126;ENST00000493286;ENST00000262735" "ENSP00000397291;ENSP00000411677;ENSP00000414752;ENSP00000385523;ENSP00000385246;ENSP00000262735" "Q07869" "PPARA" "5465" "peroxisome proliferator activated receptor alpha" "hPPAR;NR1C1;PPAR" "Nucleus" "SwissProt;CellAtlas" "ENSG00000187021" "ENST00000525157;ENST00000530626;ENST00000484402;ENST00000470678;ENST00000531984;ENST00000482159;ENST00000529584;ENST00000531825;ENST00000526223;ENST00000525820;ENST00000358834;ENST00000528052;ENST00000497792;ENST00000530319;ENST00000527980;ENST00000480870;ENST00000471549;ENST00000534537;ENST00000510125;ENST00000482833;ENST00000534513" "ENSP00000436123;ENSP00000351695;ENSP00000433933;ENSP00000431406;ENSP00000437263;ENSP00000433785;ENSP00000431207;ENSP00000434159;ENSP00000434549" "P54315" "PNLIPRP1" "5407" "pancreatic lipase related protein 1" "PLRP1" "Extracellular" "DeepLoc2" "ENSG00000187024" "ENST00000641641;ENST00000335223;ENST00000423807;ENST00000419060;ENST00000543175;ENST00000456267;ENST00000414832;ENST00000416214;ENST00000429848" "ENSP00000492921;ENSP00000493136;ENSP00000418219;ENSP00000418661;ENSP00000439469;ENSP00000485347;ENSP00000485479;ENSP00000485367" "Q86Y79" "PTRH1" "138428" "peptidyl-tRNA hydrolase 1 homolog" "C9orf115;PTH1" "Mitochondria" "DeepLoc2" "ENSG00000187048" "ENST00000310638;ENST00000475477;ENST00000462347;ENST00000474458;ENST00000468629;ENST00000465874;ENST00000371905;ENST00000496519;ENST00000371904" "ENSP00000311095;ENSP00000476854;ENSP00000477495;ENSP00000476988;ENSP00000476619;ENSP00000476368;ENSP00000360972;ENSP00000360971" "Q02928" "CYP4A11" "1579" "cytochrome P450 family 4 subfamily A member 11" "CYP4A2;CYP4AII" "Endoplasmic reticulum" "SwissProt" @@ -2599,7 +2579,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000196433" "ENST00000381241;ENST00000381229;ENST00000381233;ENST00000509780;ENST00000432523" "ENSP00000370639;ENSP00000370627;ENSP00000370631;ENSP00000392053" "P46597" "ASMT" "438" "acetylserotonin O-methyltransferase" "ASMTY;HIOMT;HIOMTY" "Cytosol" "DeepLoc2" "ENSG00000196470" "ENST00000565620;ENST00000568007;ENST00000380006;ENST00000356721;ENST00000394725;ENST00000563745;ENST00000573005;ENST00000567973" "ENSP00000456421;ENSP00000369343;ENSP00000349156;ENSP00000378214;ENSP00000457415" "Q8IUQ4" "SIAH1" "6477" "siah E3 ubiquitin protein ligase 1" "hSIAH1" "Nucleus;Mitochondria;Cytosol" "SwissProt;CellAtlas" "ENSG00000196475" "ENST00000358842" "ENSP00000351706" "Q14410" "GK2" "2712" "glycerol kinase 2" "GKP2;GKTA" "Cytosol" "SwissProt" -"ENSG00000196498" "ENST00000405201;ENST00000404621;ENST00000429285;ENST00000418829;ENST00000443451;ENST00000413172;ENST00000464377;ENST00000440337;ENST00000461081;ENST00000474079;ENST00000440187;ENST00000453428;ENST00000458234;ENST00000473999;ENST00000536195;ENST00000493859;ENST00000448614;ENST00000420698;ENST00000494460;ENST00000542927;ENST00000448008;ENST00000542565;ENST00000404121;ENST00000356219" "ENSP00000384018;ENSP00000384202;ENSP00000400281;ENSP00000391389;ENSP00000407357;ENSP00000398963;ENSP00000396044;ENSP00000400687;ENSP00000402808;ENSP00000408247;ENSP00000405367;ENSP00000443689;ENSP00000403034;ENSP00000385618;ENSP00000348551" "Q9Y618" "NCOR2" "9612" "nuclear receptor corepressor 2" "CTG26;SMRT;SMRTE;TNRC14;TRAC-1" "Nucleus" "SwissProt;CellAtlas" "ENSG00000196502" "ENST00000395609;ENST00000569554;ENST00000350842;ENST00000564818;ENST00000567998;ENST00000562058;ENST00000314752;ENST00000563493;ENST00000566189;ENST00000567512" "ENSP00000457912;ENSP00000329399;ENSP00000454388;ENSP00000456215;ENSP00000321988;ENSP00000457083;ENSP00000456459;ENSP00000455979" "P50225" "SULT1A1" "6817" "sulfotransferase family 1A member 1" "P-PST;STP;STP1" "Cytosol" "SwissProt" "ENSG00000196511" "ENST00000482940;ENST00000360057;ENST00000538212;ENST00000378098;ENST00000547966;ENST00000551062;ENST00000548831;ENST00000552881;ENST00000481645;ENST00000489798;ENST00000546806;ENST00000548460;ENST00000378099;ENST00000639328" "ENSP00000449909;ENSP00000353165;ENSP00000438813;ENSP00000367338;ENSP00000448655;ENSP00000450028;ENSP00000367339;ENSP00000491869" "Q9H3S4" "TPK1" "27010" "thiamin pyrophosphokinase 1" "HTPK1;PP20" "Cytosol" "DeepLoc2" "ENSG00000196517" "ENST00000372307;ENST00000372306;ENST00000372310;ENST00000673836;ENST00000475075;ENST00000357730;ENST00000360584;ENST00000492434;ENST00000528803;ENST00000489764;ENST00000466926;ENST00000533007" "ENSP00000361381;ENSP00000361380;ENSP00000361384;ENSP00000501314;ENSP00000434460;ENSP00000350362;ENSP00000353791;ENSP00000435652;ENSP00000433241" "P48067" "SLC6A9" "6536" "solute carrier family 6 member 9" "GLYT1" "Golgi apparatus;Nucleus" "CellAtlas" @@ -2674,7 +2653,6 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000198488" "ENST00000528622;ENST00000622824" "ENSP00000435628;ENSP00000484640" "Q6ZMB0" "B3GNT6" "192134" "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6" "B3Gn-T6" "Golgi apparatus" "SwissProt" "ENSG00000198569" "ENST00000673865;ENST00000538474;ENST00000673835;ENST00000673953;ENST00000361134" "ENSP00000501101;ENSP00000442397;ENSP00000501114;ENSP00000501108;ENSP00000355353" "Q8N130" "SLC34A3" "142680" "solute carrier family 34 member 3" "FLJ38680;NPTIIc" "Cell membrane;Lysosome" "DeepLoc2" "ENSG00000198610" "ENST00000469875;ENST00000380448;ENST00000263126" "ENSP00000369814;ENSP00000263126" "P17516" "AKR1C4" "1109" "aldo-keto reductase family 1 member C4" "3-alpha-HSD;C11;CDR;CHDR;DD4;HAKRA;MGC22581" "Endoplasmic reticulum;Nucleus;Cytosol" "SwissProt;CellAtlas" -"ENSG00000198646" "ENST00000626057;ENST00000434040;ENST00000593786;ENST00000628752;ENST00000374796;ENST00000359003;ENST00000471897;ENST00000612493;ENST00000616167" "ENSP00000486894;ENSP00000363929;ENSP00000351894;ENSP00000481177;ENSP00000481935" "Q14686" "NCOA6" "23054" "nuclear receptor coactivator 6" "AIB3;ASC2;KIAA0181;NRC;PRIP;RAP250;TRBP" "Nucleus" "SwissProt;CellAtlas" "ENSG00000198650" "ENST00000355962;ENST00000564007;ENST00000566094;ENST00000566010" "ENSP00000348234" "P17735" "TAT" "6898" "tyrosine aminotransferase" "" "Cytosol" "DeepLoc2" "ENSG00000198668" "ENST00000557020;ENST00000447653;ENST00000356978;ENST00000555132;ENST00000557123;ENST00000556757;ENST00000553995;ENST00000553630;ENST00000553542;ENST00000659177;ENST00000553964;ENST00000544280;ENST00000663135;ENST00000555267;ENST00000553422;ENST00000554296;ENST00000556721;ENST00000626705" "ENSP00000451062;ENSP00000403491;ENSP00000349467;ENSP00000451646;ENSP00000450829;ENSP00000499421;ENSP00000442853;ENSP00000499498;ENSP00000450425;ENSP00000486402" "P0DP23" "CALM1" "801" "calmodulin 1" "CALML2;CAMI;DD132;PHKD" "Cytosol" "SwissProt;CellAtlas" "ENSG00000198682" "ENST00000361175;ENST00000456849;ENST00000465996;ENST00000482258" "ENSP00000354436;ENSP00000406157" "O95340" "PAPSS2" "9060" "3'-phosphoadenosine 5'-phosphosulfate synthase 2" "ATPSK2" "Mitochondria" "CellAtlas" @@ -2887,3 +2865,22 @@ genes geneENSTID geneENSPID geneUniProtID geneSymbols geneEntrezID geneNames gen "ENSG00000281500" "ENST00000525102;ENST00000330775;ENST00000357590;ENST00000538950;ENST00000545985;ENST00000526275;ENST00000532085;ENST00000650539;ENST00000527992;ENST00000638925;ENST00000638360;ENST00000638186;ENST00000530407;ENST00000524428;ENST00000525372;ENST00000525039;ENST00000529510;ENST00000532888;ENST00000526626;ENST00000525787;ENST00000534384" "ENSP00000476242;ENSP00000476176;ENSP00000475991;ENSP00000475241" "O43826" "SLC37A4" "" "Glucose-6-phosphate exchanger" "G6PT,G6PT1" "Endoplasmic reticulum" "SwissProt" "ENSG00000288702" "ENST00000482026" "ENSP00000418532" "P35503" "UGT1A3" "54659" "UDP glucuronosyltransferase family 1 member A3" "UGT1C" "Endoplasmic reticulum" "SwissProt" "ENSG00000288705" "ENST00000373414" "ENSP00000362513" "P35504" "UGT1A5" "54579" "UDP glucuronosyltransferase family 1 member A5" "UGT1E" "Endoplasmic reticulum" "SwissProt" +"ENSG00000007314" "ENST00000435607" "ENSP00000396320" "P35499" "SCN4A" "6329" "sodium voltage-gated channel alpha subunit 4" "" "" "" +"ENSG00000102452" "ENST00000675594;ENST00000497170;ENST00000675802;ENST00000251127;ENST00000376200;ENST00000467264;ENST00000676315;ENST00000648359;ENST00000675150;ENST00000675332" "ENSP00000502675;ENSP00000501603;ENSP00000365373;ENSP00000501955;ENSP00000502680;ENSP00000497465;ENSP00000501818;ENSP00000502490;ENSP00000251127;ENSP00000502148" "Q8IZF0" "NALCN" "259232" "sodium leak channel, non-selective" "" "" "" +"ENSG00000136531" "ENST00000636769;ENST00000637367;ENST00000673831;ENST00000674133;ENST00000486878;ENST00000636071;ENST00000631182;ENST00000424833;ENST00000673883;ENST00000636135;ENST00000636384;ENST00000636662;ENST00000283256;ENST00000375437;ENST00000637266;ENST00000636985" "ENSP00000406454;ENSP00000490592;ENSP00000364586;ENSP00000490765;ENSP00000490107;ENSP00000501305;ENSP00000490849;ENSP00000501309;ENSP00000486885;ENSP00000489873;ENSP00000489821;ENSP00000283256;ENSP00000487466;ENSP00000490800;ENSP00000500975;ENSP00000490866" "Q99250" "SCN2A" "6326" "sodium voltage-gated channel alpha subunit 2" "" "" "" +"ENSG00000136546" "ENST00000650747;ENST00000643258;ENST00000419992;ENST00000424326;ENST00000441411" "ENSP00000496114;ENSP00000498959;ENSP00000413699;ENSP00000403846;ENSP00000396600" "Q01118" "SCN7A" "6332" "sodium voltage-gated channel alpha subunit 7" "" "" "" +"ENSG00000138622" "ENST00000261917" "ENSP00000261917" "Q9Y3Q4" "HCN4" "10021" "hyperpolarization activated cyclic nucleotide gated potassium channel 4" "" "" "" +"ENSG00000144285" "ENST00000689288;ENST00000409050;ENST00000674923;ENST00000636759;ENST00000641603;ENST00000641996;ENST00000637988;ENST00000637285;ENST00000641575;ENST00000671940;ENST00000635750;ENST00000375405;ENST00000636194;ENST00000303395;ENST00000637038;ENST00000635776;ENST00000640036" "ENSP00000490612;ENSP00000490780;ENSP00000490895;ENSP00000492917;ENSP00000500336;ENSP00000303540;ENSP00000509637;ENSP00000490799;ENSP00000364554;ENSP00000493054;ENSP00000490692;ENSP00000492945;ENSP00000490288;ENSP00000501589;ENSP00000386312;ENSP00000491573;ENSP00000490184" "P35498" "SCN1A" "6323" "sodium voltage-gated channel alpha subunit 1" "" "" "" +"ENSG00000162341" "ENST00000637342;ENST00000635811;ENST00000294309;ENST00000637504;ENST00000542467" "ENSP00000490341;ENSP00000294309;ENSP00000445551;ENSP00000490171;ENSP00000489759" "Q8NHX9" "TPCN2" "219931" "two pore segment channel 2" "" "" "" +"ENSG00000164588" "ENST00000634658;ENST00000673735;ENST00000303230" "ENSP00000489134;ENSP00000501107;ENSP00000307342" "O60741" "HCN1" "348980" "hyperpolarization activated cyclic nucleotide gated potassium channel 1" "" "" "" +"ENSG00000168356" "ENST00000675892;ENST00000675223;ENST00000444237;ENST00000676045;ENST00000456224;ENST00000676176;ENST00000675672;ENST00000668754;ENST00000302328" "ENSP00000502318;ENSP00000499569;ENSP00000408028;ENSP00000502481;ENSP00000502446;ENSP00000307599;ENSP00000416757;ENSP00000501891;ENSP00000501685" "Q9UI33" "SCN11A" "11280" "sodium voltage-gated channel alpha subunit 11" "" "" "" +"ENSG00000169432" "ENST00000645907;ENST00000452182;ENST00000303354;ENST00000643319;ENST00000645283;ENST00000642356;ENST00000667991;ENST00000667201;ENST00000454569;ENST00000409672" "ENSP00000386306;ENSP00000495983;ENSP00000413212;ENSP00000496086;ENSP00000499663;ENSP00000304748;ENSP00000393141;ENSP00000499341;ENSP00000494071;ENSP00000495601" "Q15858" "SCN9A" "6335" "sodium voltage-gated channel alpha subunit 9" "" "" "" +"ENSG00000183873" "ENST00000333535;ENST00000413689;ENST00000414099;ENST00000450102;ENST00000449557;ENST00000455624;ENST00000423572;ENST00000327956" "ENSP00000398266;ENSP00000413996;ENSP00000410257;ENSP00000399524;ENSP00000398962;ENSP00000333674;ENSP00000328968;ENSP00000403355" "Q14524" "SCN5A" "6331" "sodium voltage-gated channel alpha subunit 5" "" "" "" +"ENSG00000185313" "ENST00000655275;ENST00000449082;ENST00000643924" "ENSP00000499510;ENSP00000495595;ENSP00000390600" "Q9Y5Y9" "SCN10A" "6336" "sodium voltage-gated channel alpha subunit 10" "" "" "" +"ENSG00000186815" "ENST00000335509;ENST00000551099;ENST00000552642;ENST00000392569;ENST00000552985;ENST00000552542;ENST00000547955;ENST00000547275;ENST00000548465;ENST00000546781;ENST00000550873;ENST00000551096;ENST00000549279;ENST00000541517;ENST00000550785;ENST00000552897" "ENSP00000448010;ENSP00000448561;ENSP00000449560;ENSP00000447569;ENSP00000438125;ENSP00000335300;ENSP00000446767;ENSP00000448083;ENSP00000447181;ENSP00000447806;ENSP00000447263;ENSP00000448704;ENSP00000447073;ENSP00000449944;ENSP00000449564;ENSP00000376350" "Q9ULQ1" "TPCN1" "53373" "two pore segment channel 1" "" "" "" +"ENSG00000196876" "ENST00000662684;ENST00000627620;ENST00000599343;ENST00000548086;ENST00000551216;ENST00000355133;ENST00000667214;ENST00000546961;ENST00000545061;ENST00000638820;ENST00000354534;ENST00000637709;ENST00000636945;ENST00000668547" "ENSP00000447567;ENSP00000499511;ENSP00000490470;ENSP00000492157;ENSP00000499724;ENSP00000486828;ENSP00000347255;ENSP00000476447;ENSP00000346534;ENSP00000487583;ENSP00000490580;ENSP00000440360;ENSP00000499691;ENSP00000499636" "Q9UQD0" "SCN8A" "6334" "sodium voltage-gated channel alpha subunit 8" "" "" "" +"ENSG00000166828" "ENST00000300061" "ENSP00000300061" "P51170" "SCNN1G" "6340" "sodium channel epithelial 1 subunit gamma" "" "" "" +"ENSG00000168447" "ENST00000343070;ENST00000307331;ENST00000568923;ENST00000568085;ENST00000566441" "ENSP00000345751;ENSP00000302874;ENSP00000456309;ENSP00000455673;ENSP00000482681" "P51168" "SCNN1B" "6338" "sodium channel epithelial 1 subunit beta" "" "" "" +"ENSG00000111319" "ENST00000228916;ENST00000360168;ENST00000540037;ENST00000543768;ENST00000396966;ENST00000536788" "ENSP00000228916;ENSP00000353292;ENSP00000440876;ENSP00000438739;ENSP00000380166;ENSP00000443434" "P37088" "SCNN1A" "6337" "sodium channel epithelial 1 subunit alpha" "" "" "" +"ENSG00000162572" "ENST00000379116;ENST00000338555;ENST00000400928;ENST00000325425;ENST00000379099;ENST00000470022" "ENSP00000368411;ENSP00000339504;ENSP00000383717;ENSP00000321594;ENSP00000368393;ENSP00000420548" "P51172" "SCNN1D" "6339" "sodium channel epithelial 1 subunit delta" "" "" "" +"ENSG00000153253" "ENST00000283254;ENST00000706067;ENST00000639244;ENST00000409101;ENST00000668657;ENST00000440431;ENST00000453007" "ENSP00000283254;ENSP00000516211;ENSP00000492251;ENSP00000386726;ENSP00000499420;ENSP00000403348;ENSP00000391569" "Q9NY46" "SCN3A" "6328" "sodium voltage-gated channel alpha subunit 3" "" "" "" diff --git a/model/metabolites.tsv b/model/metabolites.tsv index 0c1df8c0..8e1e6f82 100644 --- a/model/metabolites.tsv +++ b/model/metabolites.tsv @@ -85,7 +85,6 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM00035c" "MAM00035" "2425dhvitd3" "C07712" "" "CHEBI:28818" "" "LMST03020273" "" "" "2425dhvitd3" "MNXM6763" "m00035c" "m00035c" "MAM00035m" "MAM00035" "2425dhvitd3" "C07712" "" "CHEBI:28818" "" "LMST03020273" "" "" "2425dhvitd3" "MNXM6763" "m00035m" "m00035m" "MAM00035e" "MAM00035" "2425dhvitd3" "C07712" "" "CHEBI:28818" "" "LMST03020273" "" "" "2425dhvitd3" "MNXM6763" "m00035s" "m00035s" -"MAM00036m" "MAM00036" "" "C05450" "" "CHEBI:52050" "46224537" "" "CE5168" "" "HC01459" "MNXM732;MNXM827" "m00036m" "m00036m" "MAM00036x" "MAM00036" "" "C05450" "" "CHEBI:52050" "46224537" "" "CE5168" "" "HC01459" "MNXM732;MNXM827" "m00036p" "m00036p" "MAM00037x" "MAM00037" "thcholoylcoa" "C05448" "" "CHEBI:27403" "46224536" "" "" "" "thcholoylcoa" "MNXM165175;MNXM3395;MNXM560" "m00037p" "m00037p" "MAM00038c" "MAM00038" "" "C05754" "" "" "" "" "" "HC01597" "HC01597" "MNXM28221" "m00038c" "m00038c" @@ -1014,11 +1013,9 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM00615c" "MAM00615" "" "" "" "" "" "" "" "" "M00615" "MNXM827" "m00615c" "m00615c" "MAM00615x" "MAM00615" "" "" "" "" "" "" "" "" "M00615" "MNXM827" "m00615p" "m00615p" "MAM00616c" "MAM00616" "cholcoar" "C15613" "" "CHEBI:37642" "15942889" "LMST01010218" "CE5165" "HC01348" "cholcoar" "MNXM549;MNXM90922;MNXM91096" "m00616c" "m00616c" -"MAM00616m" "MAM00616" "cholcoar" "C15613" "" "CHEBI:37642" "15942889" "LMST01010218" "CE5165" "HC01348" "cholcoar" "MNXM549;MNXM90922;MNXM91096" "m00616m" "m00616m" "MAM00616x" "MAM00616" "cholcoar" "C15613" "" "CHEBI:37642" "15942889" "LMST01010218" "CE5165" "HC01348" "cholcoar" "MNXM549;MNXM90922;MNXM91096" "m00616p" "m00616p" "MAM00616r" "MAM00616" "cholcoar" "C15613" "" "CHEBI:37642" "15942889" "LMST01010218" "CE5165" "HC01348" "cholcoar" "MNXM549;MNXM90922;MNXM91096" "m00616r" "m00616r" "MAM00617x" "MAM00617" "" "C17346" "" "" "" "" "" "" "M00617" "MNXM5367" "m00617p" "m00617p" -"MAM00618m" "MAM00618" "cholcoas" "C17343" "" "CHEBI:37643" "15942888" "" "CE5166" "" "CE5166;cholcoas" "MNXM1201;MNXM8131" "m00618m" "m00618m" "MAM00618x" "MAM00618" "cholcoas" "C17343" "" "CHEBI:37643" "15942888" "" "CE5166" "" "CE5166;cholcoas" "MNXM1201;MNXM8131" "m00618p" "m00618p" "MAM00619r" "MAM00619" "xol25oh" "" "" "" "65094" "LMST01010018" "" "" "xol25oh" "MNXM852" "m00619r" "m00619r" "MAM00620c" "MAM00620" "25hvitd2" "" "HMDB0001438" "" "22833566" "" "" "" "25hvitd2" "MNXM4976" "m00620c" "m00620c" @@ -1219,9 +1216,7 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM00745r" "MAM00745" "" "C04483" "HMDB0000626" "CHEBI:28834" "222528" "LMST04010040" "" "" "dchac" "MNXM57907" "m00745r" "m00745r" "MAM00746m" "MAM00746" "" "" "" "" "" "LMST04030155" "" "" "M00746" "MNXM30747;MNXM36899" "m00746m" "m00746m" "MAM00747r" "MAM00747" "" "" "" "" "" "" "CE1274" "" "CE1274" "MNXM151029" "m00747r" "m00747r" -"MAM00748m" "MAM00748" "cholcoaone" "C05467" "HMDB0006891" "CHEBI:27379" "440690" "LMST01010216" "CE5169" "HC01473" "cholcoaone" "MNXM162946;MNXM873" "m00748m" "m00748m;MAM03368m" "MAM00748x" "MAM00748" "cholcoaone" "C05467" "HMDB0006891" "CHEBI:27379" "440690" "LMST01010216" "CE5169" "HC01473" "cholcoaone" "MNXM162946;MNXM873" "m00748p" "m00748p;MAM03368x" -"MAM00749m" "MAM00749" "cholcoads" "C05460" "HMDB0006889" "CHEBI:27505" "5280797" "LMST01010217" "" "HC01466" "cholcoads" "MNXM162945;MNXM2747" "m00749m" "m00749m" "MAM00749x" "MAM00749" "cholcoads" "C05460" "HMDB0006889" "CHEBI:27505" "5280797" "LMST01010217" "" "HC01466" "cholcoads" "MNXM162945;MNXM2747" "m00749p" "m00749p" "MAM00750c" "MAM00750" "thcholst" "C01301" "" "CHEBI:48940" "439479" "LMST04030164" "" "HC00757" "thcholst" "MNXM162326;MNXM163900;MNXM867;MNXM90392" "m00750c" "m00750c" "MAM00750m" "MAM00750" "thcholst" "C01301" "" "CHEBI:48940" "439479" "LMST04030164" "" "HC00757" "thcholst" "MNXM162326;MNXM163900;MNXM867;MNXM90392" "m00750m" "m00750m" @@ -1995,12 +1990,6 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM01265m" "MAM01265" "prpncoa" "C00894" "" "CHEBI:15513" "439340" "" "" "HC00579" "prpncoa" "MNXM650" "m01265m" "m01265m" "MAM01266c" "MAM01266" "" "C10905" "" "" "" "" "" "HC01797" "HC01797" "MNXM2964" "m01266c" "m01266c" "MAM01267c" "MAM01267" "" "" "" "" "" "" "" "HC02116" "HC02116" "MNXM166880" "m01267c" "m01267c" -"MAM01268c" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268c" "m01268c" -"MAM01268m" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268m" "m01268m" -"MAM01268n" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268n" "m01268n" -"MAM01268x" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268p" "m01268p" -"MAM01268r" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268r" "m01268r" -"MAM01268e" "MAM01268" "" "" "" "" "" "PROTEIN" "" "" "M01268" "" "m01268s" "m01268s" "MAM01269c" "MAM01269" "" "" "" "" "" "" "" "HC02082" "HC02082" "" "m01269c" "m01269c" "MAM01270c" "MAM01270" "" "" "" "" "" "" "" "HC02089" "HC02089" "" "m01270c" "m01270c" "MAM01271c" "MAM01271" "" "" "" "" "" "" "" "HC02044" "HC02044" "" "m01271c" "m01271c" @@ -2345,7 +2334,6 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM01443c" "MAM01443" "" "C06755" "" "CHEBI:27869" "" "" "" "" "M01443" "MNXM1468" "m01443c" "m01443c" "MAM01444c" "MAM01444" "" "C14859" "" "" "" "" "" "" "M01444" "MNXM5082" "m01444c" "m01444c" "MAM01445c" "MAM01445" "cholate" "C00695" "HMDB0000619" "CHEBI:16359" "221493" "LMST04010001" "" "HC00502" "cholate" "MNXM450" "m01445c" "m01445c" -"MAM01445m" "MAM01445" "cholate" "C00695" "HMDB0000619" "CHEBI:16359" "221493" "LMST04010001" "" "HC00502" "cholate" "MNXM450" "m01445m" "m01445m" "MAM01445x" "MAM01445" "cholate" "C00695" "HMDB0000619" "CHEBI:16359" "221493" "LMST04010001" "" "HC00502" "cholate" "MNXM450" "m01445p" "m01445p" "MAM01445r" "MAM01445" "cholate" "C00695" "HMDB0000619" "CHEBI:16359" "221493" "LMST04010001" "" "HC00502" "cholate" "MNXM450" "m01445r" "m01445r" "MAM01445e" "MAM01445" "cholate" "C00695" "HMDB0000619" "CHEBI:16359" "221493" "LMST04010001" "" "HC00502" "cholate" "MNXM450" "m01445s" "m01445s" @@ -2493,7 +2481,6 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM01513r" "MAM01513" "chol" "C00114" "HMDB0000097" "CHEBI:15354" "305" "" "" "HC00112" "chol" "MNXM90" "m01513r" "m01513r" "MAM01513e" "MAM01513" "chol" "C00114" "HMDB0000097" "CHEBI:15354" "305" "" "" "HC00112" "chol" "MNXM90" "m01513s" "m01513s" "MAM01514c" "MAM01514" "cholcoa" "C01794" "HMDB0001374" "CHEBI:15519" "439573" "" "" "HC00844" "cholcoa" "MNXM162468;MNXM431" "m01514c" "m01514c" -"MAM01514m" "MAM01514" "cholcoa" "C01794" "HMDB0001374" "CHEBI:15519" "439573" "" "" "HC00844" "cholcoa" "MNXM162468;MNXM431" "m01514m" "m01514m" "MAM01514x" "MAM01514" "cholcoa" "C01794" "HMDB0001374" "CHEBI:15519" "439573" "" "" "HC00844" "cholcoa" "MNXM162468;MNXM431" "m01514p" "m01514p" "MAM01514r" "MAM01514" "cholcoa" "C01794" "HMDB0001374" "CHEBI:15519" "439573" "" "" "HC00844" "cholcoa" "MNXM162468;MNXM431" "m01514r" "m01514r" "MAM01515g" "MAM01515" "cs_a_b_pre2" "" "" "" "" "" "" "" "cs_a_b_pre2" "MNXM148157" "m01515g" "m01515g" @@ -3114,7 +3101,6 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM01813c" "MAM01813" "" "C00162" "" "CHEBI:35366" "" "" "" "HC02065" "HC02065" "MNXM72" "m01813c" "m01813c" "MAM01814c" "MAM01814" "" "C00162" "" "CHEBI:35366" "" "" "" "HC02064" "HC02064" "MNXM72" "m01814c" "m01814c" "MAM01815c" "MAM01815" "" "C00162" "" "CHEBI:35366" "" "" "" "HC02063" "HC02063" "MNXM72" "m01815c" "m01815c" -"MAM01816n" "MAM01816" "" "" "" "" "" "PROTEIN" "" "" "M01816" "" "m01816n" "m01816n" "MAM01819e" "MAM01819" "" "C00162" "" "CHEBI:35366" "" "" "" "" "M01819" "MNXM72" "m01819s" "m01819s" "MAM01820e" "MAM01820" "" "C00162" "" "CHEBI:35366" "" "" "" "" "M01820" "MNXM72" "m01820s" "m01820s" "MAM01821c" "MAM01821" "fe2" "C14818" "HMDB0000692" "CHEBI:29033" "27284" "" "" "HC01846" "fe2" "MNXM111" "m01821c" "m01821c" @@ -4750,9 +4736,6 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM02754e" "MAM02754" "4nph" "C00870" "" "CHEBI:16836" "" "" "" "HC00570" "4nph" "MNXM162908" "m02754s" "m02754s" "MAM02755c" "MAM02755" "" "C00419" "" "CHEBI:15986" "" "" "" "" "M02755" "MNXM162987" "m02755c" "m02755c" "MAM02756c" "MAM02756" "ppbng" "C00931" "HMDB0000245" "CHEBI:17381" "1021" "" "" "HC00588" "ppbng" "MNXM554" "m02756c" "m02756c" -"MAM02757c" "MAM02757" "" "" "" "" "" "" "" "" "M02757" "" "m02757c" "m02757c" -"MAM02757l" "MAM02757" "" "" "" "" "" "" "" "" "M02757" "" "m02757l" "m02757l" -"MAM02757n" "MAM02757" "" "" "" "" "" "" "" "" "M02757" "" "m02757n" "m02757n" "MAM02758c" "MAM02758" "" "C04308" "" "" "" "LMGP0201AB00" "" "" "M02758" "MNXM75100" "m02758c" "m02758c" "MAM02759c" "MAM02759" "ppi" "C00013" "HMDB0000250" "CHEBI:18361" "644102" "" "" "HC00023" "ppi" "MNXM11" "m02759c" "m02759c" "MAM02759m" "MAM02759" "ppi" "C00013" "HMDB0000250" "CHEBI:18361" "644102" "" "" "HC00023" "ppi" "MNXM11" "m02759m" "m02759m" @@ -6086,7 +6069,6 @@ mets metsNoComp metBiGGID metKEGGID metHMDBID metChEBIID metPubChemID metLipidMa "MAM03365r" "MAM03365" "CE5161" "" "" "" "" "" "CE5161" "" "CE5161" "MNXM163175" "" "CE5161_r" "MAM03366c" "MAM03366" "CE5162" "" "" "" "" "" "CE5162" "" "CE5162" "MNXM163591" "" "CE5162_c" "MAM03366r" "MAM03366" "CE5162" "" "" "" "" "" "CE5162" "" "CE5162" "MNXM163591" "" "CE5162_r" -"MAM03367m" "MAM03367" "" "" "" "" "" "" "CE5168" "" "CE5168" "" "" "CE5168_m" "MAM03367x" "MAM03367" "" "" "" "" "" "" "CE5168" "" "CE5168" "" "" "CE5168_p" "MAM03367c" "MAM03367" "CE5168" "" "" "" "" "" "CE5168" "" "CE5168" "MNXM166027" "" "CE5168_c" "MAM03368c" "MAM03368" "" "C05467" "HMDB0006891" "CHEBI:27379" "440690" "" "CE5169" "" "CE5169" "" "" "CE5169_c" diff --git a/model/reactions.tsv b/model/reactions.tsv index ee787009..b86a9515 100644 --- a/model/reactions.tsv +++ b/model/reactions.tsv @@ -1252,7 +1252,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR05170" "" "" "" "" "" "HMR_5170" "" "HMR_5170" "RCR14472" "" 0 "" "" "HMR_5170" "MAR05171" "" "" "" "" "" "HMR_5171" "" "HMR_5171" "RCR14473" "" 0 "" "" "HMR_5171" "MAR05172" "" "" "" "r1402" "" "HMR_5172;r1402" "" "HMR_5172" "RCR14474" "" 0 "" "" "HMR_5172" -"MAR05173" "" "" "" "" "" "HMR_5173" "" "HMR_5173" "RCR14475" "" 0 "" "" "HMR_5173" "MAR05174" "" "" "" "" "" "HMR_5174" "" "HMR_5174" "RCR14476" "" 0 "" "" "HMR_5174" "MAR07282" "" "" "" "" "" "" "" "HMR_7282" "RCR11617" "" 0 "" "" "HMR_7282" "MAR07616" "" "" "" "" "" "HMR_7616" "" "HMR_7616" "RCR10348" "" 0 "" "" "HMR_7616" @@ -1293,7 +1292,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR05286" "" "" "" "" "" "HMR_5286" "" "HMR_5286" "RCR11641" "" 0 "" "" "HMR_5286" "MAR05287" "" "" "" "" "" "HMR_5287" "" "HMR_5287" "RCR11642" "" 0 "" "" "HMR_5287" "MAR05288" "" "" "" "r1403" "" "r1403" "" "HMR_5288" "RCR10594" "" 0 "" "" "HMR_5288" -"MAR05289" "" "" "" "" "" "HMR_5289" "" "HMR_5289" "RCR14478" "" 0 "" "" "HMR_5289" "MAR05290" "" "" "" "" "" "HMR_5290" "" "HMR_5290" "RCR11643" "" 0 "" "" "HMR_5290" "MAR05291" "" "" "" "" "" "HMR_5291" "" "HMR_5291" "RCR11644" "" 0 "" "" "HMR_5291" "MAR09817" "" "" "" "" "" "HMR_9817" "" "HMR_9817" "RCR10595" "" 0 "" "" "HMR_9817" @@ -2848,8 +2846,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR07169" "R09847" "" "" "" "" "HMR_7169" "MNXR113248" "HMR_7169" "RCR12827" "" 0 "" "" "HMR_7169" "MAR07170" "R09562" "" "" "" "" "HMR_7170" "MNXR112981" "HMR_7170" "RCR12828" "" 0 "" "RHEA:30231" "HMR_7170" "MAR09722" "R03816" "" "" "" "" "HMR_9722" "MNXR108448" "HMR_9722" "RCR12829" "" 0 "" "RHEA:74075" "HMR_9722" -"MAR01644" "R04813" "" "RE3248M" "" "" "HMR_1644" "" "HMR_1644" "RCR12830" "" 0 "" "RHEA:18933" "HMR_1644" -"MAR01651" "R04812" "" "RE3250M" "" "" "HMR_1651" "" "HMR_1651" "RCR12831" "" 0 "" "" "HMR_1651" "MAR01920" "R08941" "" "RE1100C" "" "" "RE1100C" "MNXR104607;MNXR112432" "HMR_1920" "RCR10697" "" 0 "" "" "HMR_1920" "MAR01924" "" "" "" "" "R-HSA-196126" "" "" "HMR_1924" "RCR12832" "" 0 "" "" "HMR_1924" "MAR01926" "" "" "" "" "R-HSA-196086" "" "" "HMR_1926" "RCR12833" "" 0 "" "" "HMR_1926" @@ -3755,12 +3751,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR07610" "R04321" "" "" "" "" "HMR_7610" "MNXR108810" "HMR_7610" "RCR14616" "" 0 "" "RHEA:36183" "HMR_7610" "MAR07614" "R03438" "" "" "" "" "HMR_7614" "MNXR108170" "HMR_7614" "RCR10262" "" 0 "" "RHEA:23992" "HMR_7614" "MAR07615" "R07387" "" "" "" "" "HMR_7615" "MNXR111044" "HMR_7615" "RCR13366" "" 0 "" "RHEA:36231" "HMR_7615" -"MAR00024" "" "" "" "" "" "HMR_0024" "" "HMR_0024" "RCR13367" "" 0 "" "" "HMR_0024" -"MAR00025" "" "" "" "" "" "HMR_0025;HMR_0030" "" "HMR_0025;HMR_0030" "RCR20226;RCR20227" "" 0 "" "" "HMR_0025;HMR_0030;MAR00030" -"MAR00026" "" "" "" "" "" "HMR_0026" "" "HMR_0026" "RCR21051" "" 0 "" "" "HMR_0026" -"MAR00027" "" "" "" "" "" "HMR_0027" "" "HMR_0027" "RCR21052" "" 0 "" "" "HMR_0027" -"MAR00028" "" "" "" "" "" "HMR_0028" "" "HMR_0028" "RCR21053" "" 0 "" "" "HMR_0028" -"MAR00029" "" "" "" "" "" "HMR_0029" "" "HMR_0029" "RCR40953" "" 0 "" "" "HMR_0029" "MAR07200" "R05925" "XYLTer" "" "" "" "XYLTer" "MNXR105263;MNXR109949" "HMR_7200" "RCR13368" "" 0 "" "RHEA:50192" "HMR_7200" "MAR07202" "R05926" "GALTg" "" "" "" "GALTg" "MNXR100017;MNXR109950" "HMR_7202" "RCR14617" "" 0 "" "RHEA:15297" "HMR_7202" "MAR07203" "R05927" "GALT2g" "" "" "" "GALT2g" "MNXR100016" "HMR_7203" "RCR13369" "" 0 "" "RHEA:11780" "HMR_7203" @@ -4042,25 +4032,18 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR01624" "R08733" "VLCSr" "R04580R" "r0703" "" "VLCSr" "MNXR105207;MNXR108978" "HMR_1624" "RCR13605" "" 0 "" "" "HMR_1624" "MAR01625" "R08733" "VLCSp" "" "" "" "VLCSp" "MNXR105207" "HMR_1625" "RCR10914" "" 0 "" "" "HMR_1625" "MAR01627" "R08733" "" "" "" "R-HSA-193401" "HMR_1627" "MNXR112239" "HMR_1627" "RCR10394" "" 0 "" "" "HMR_1627" -"MAR01629" "" "" "" "" "R-HSA-192325" "HMR_1629" "MNXR125295" "HMR_1629" "RCR20233" "" 0 "" "" "HMR_1629" -"MAR01630" "" "" "" "" "R-HSA-192325" "HMR_1630" "MNXR125295" "HMR_1630" "RCR20511" "" 0 "" "" "HMR_1630" +"MAR01629" "" "" "" "" "R-HSA-192325" "HMR_1629;HMR_1630" "MNXR125295" "HMR_1629;HMR_1630" "RCR20233;RCR20511" "" 0 "" "" "HMR_1629" "MAR01631" "" "" "" "" "R-HSA-192325" "HMR_1631" "MNXR125295" "HMR_1631" "RCR20512" "" 0 "" "" "HMR_1631" -"MAR01632" "R08734" "" "RE2624X" "" "R-HSA-192056" "AMACRp;RE2624X" "MNXR112240" "HMR_1632" "RCR10915" "" 0 "RHEA:40456" "RHEA:40455" "HMR_1632" -"MAR01635" "R08734" "" "RE2624M" "" "R-HSA-192056" "HMR_1635;RE2624M" "MNXR112240" "HMR_1635" "RCR13606" "" 0 "RHEA:40456" "RHEA:40455" "HMR_1635" -"MAR01637" "" "" "RE3247M" "r0706" "R-HSA-192335" "HMR_1637;RE3247M" "MNXR105369;MNXR124225" "HMR_1637" "RCR13607" "" 0 "" "" "HMR_1637" -"MAR01638" "" "ACOX2x" "" "" "" "ACOX2x" "" "HMR_1638" "RCR10916" "" 0 "" "" "HMR_1638" -"MAR01639" "" "" "RE3247X" "r0706" "R-HSA-192335" "RE3247X;r0706" "MNXR105369;MNXR124225" "HMR_1639" "RCR10917" "" 0 "" "" "HMR_1639" -"MAR01642" "R04813" "" "" "r0744" "R-HSA-192331" "r0744" "MNXR105377;MNXR109137;MNXR115598" "HMR_1642" "RCR10918" "" 0 "" "RHEA:18933" "HMR_1642" -"MAR01646" "R04812" "" "" "r0743" "" "r0743" "MNXR105376;MNXR109136" "HMR_1646" "RCR13608" "" 0 "" "" "HMR_1646" -"MAR01652" "R03719" "SCPx" "R03719X" "r0628" "" "SCPx" "MNXR104297;MNXR108369" "HMR_1652" "RCR13609" "" 0 "" "RHEA:16865" "HMR_1652" -"MAR01653" "R03719" "SCPx" "R03719X" "r0628" "" "HMR_1653" "MNXR104297;MNXR108369" "HMR_1653" "RCR13610" "" 0 "" "RHEA:16865" "HMR_1653" -"MAR01656" "" "" "" "r0990" "" "r0990" "MNXR105412" "HMR_1656" "RCR20134" "" 0 "" "" "HMR_1656" -"MAR01659" "" "" "" "r2501" "" "r2501" "MNXR106313" "HMR_1659" "RCR20234" "3.A.1.203.3" 0 "" "" "HMR_1659" +"MAR01632" "R08734" "" "RE2624X" "" "R-HSA-192056" "AMACRp;RE2624X;HMR_1635;RE2624M" "MNXR112240" "HMR_1632;HMR_1635" "RCR10915;RCR13606" "" 0 "RHEA:40456" "RHEA:40455" "HMR_1632" +"MAR01638" "" "ACOX2x" "RE3247M" "r0706" "R-HSA-192335" "ACOX2x;HMR_1637;RE3247M" "MNXR105369;MNXR124225" "HMR_1638;HMR_1637" "RCR10916;RCR13607" "" 0 "" "" "HMR_1638" +"MAR01639" "" "" "RE3247X;RE3247M" "r0706" "R-HSA-192335" "RE3247X;r0706;HMR_1637;RE3247M" "MNXR105369;MNXR124225" "HMR_1639;HMR_1637" "RCR10917;RCR13607" "" 0 "" "" "HMR_1639;HMR_1637;MAR01637" +"MAR01642" "R04813" "HSD17B4x" "RE3248M" "r0744" "R-HSA-192331" "r0744;HMR_1644;HSD17B4x" "MNXR105377;MNXR109137;MNXR115598;MNXR100720" "HMR_1642;HMR_1644" "RCR10918;RCR12830" "" 0 "" "RHEA:18933" "HMR_1642;HMR_1644;MAR01644;HSD17B4x;MAR01458" +"MAR01646" "R04812" "HSD17B4x" "RE3250M" "r0743" "" "r0743;HMR_1651;HSD17B4x" "MNXR105376;MNXR109136;MNXR100720" "HMR_1646;HMR_1651" "RCR13608;RCR12831" "" 0 "" "" "HMR_1646;HMR_1651;MAR01651;HSD17B4x;MAR01458" +"MAR01652" "R03719" "SCPx" "R03719X" "r0628" "" "SCPx;HMR_1653" "MNXR104297;MNXR108369" "HMR_1652;HMR_1653" "RCR13609;RCR13610" "" 0 "" "RHEA:16865" "HMR_1652;HMR_1653;MAR01653" +"MAR01659" "" "" "" "r2501;r0990" "" "r2501;r0990" "MNXR106313;MNXR105412" "HMR_1659;HMR_1656" "RCR20234;RCR20134" "3.A.1.203.3" 0 "" "" "HMR_1659;HMR_1565;MAR01656" "MAR01660" "R07296" "" "RE1834C" "r0794" "" "RE1834C" "MNXR103558;MNXR110971" "HMR_1660" "RCR10217" "" 0 "RHEA:14542" "RHEA:14541" "HMR_1660" -"MAR01662" "R07296" "" "RE1834M" "" "" "RE1834M" "MNXR103558;MNXR110971" "HMR_1662" "RCR13611" "" 0 "RHEA:14542" "RHEA:14541" "HMR_1662" -"MAR01663" "R07296" "" "RE1834X" "" "" "RE1834X" "MNXR103558;MNXR110971" "HMR_1663" "RCR13612" "" 0 "RHEA:14542" "RHEA:14541" "HMR_1663" -"MAR01665" "" "" "" "" "R-HSA-193399" "HMR_1665" "MNXR125298" "HMR_1665" "RCR20513" "" 0 "RHEA:72683" "RHEA:72683" "HMR_1665" -"MAR01666" "" "" "" "" "R-HSA-193399" "HMR_1666" "MNXR125298" "HMR_1666" "RCR20514" "" 0 "RHEA:72683" "RHEA:72683" "HMR_1666" +"MAR01663" "R07296" "" "RE1834X;RE1834M" "" "" "RE1834X;RE1834M" "MNXR103558;MNXR110971" "HMR_1663;HMR_1662" "RCR13612;RCR13611" "" 0 "RHEA:14542" "RHEA:14541" "HMR_1663;HMR_1662;MAR01662" +"MAR01665" "" "" "" "" "R-HSA-193399" "HMR_1665;HMR_1666" "MNXR125298" "HMR_1665;HMR_1666" "RCR20513;RCR20514" "" 0 "RHEA:72683" "RHEA:72683" "HMR_1665;HMR_1666;MAR01666" "MAR01667" "R03720" "BAAT2x" "R03720C" "r0631" "" "BAAT2x" "MNXR108370;MNXR96203" "HMR_1667" "RCR10919" "" 0 "" "" "HMR_1667" "MAR01668" "R03720" "" "R03720C" "r0630" "" "r0630" "MNXR108370;MNXR96203" "HMR_1668" "RCR13613" "" 0 "" "" "HMR_1668" "MAR01670" "R03718" "" "" "r0629" "" "r0629" "MNXR108368;MNXR96202" "HMR_1670" "RCR10218" "" 0 "" "RHEA:14001" "HMR_1670" @@ -6892,7 +6875,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR07719" "" "Uritm" "" "" "" "Uritm" "MNXR105165" "HMR_7719" "RCR20632" "" 0 "" "" "HMR_7719" "MAR07723" "" "CYTDtm" "" "" "" "CYTDtm" "MNXR97043" "HMR_7723" "RCR20633" "" 0 "" "" "HMR_7723" "MAR07757" "" "" "RT0107" "" "" "HMR_7757" "" "HMR_7757" "RCR20634" "" 0 "" "" "HMR_7757" -"MAR07758" "" "" "RT0402" "" "" "HMR_7758" "" "HMR_7758" "RCR20277" "" 0 "" "" "HMR_7758" "MAR07760" "" "" "RT0468" "" "" "HMR_7760" "" "HMR_7760" "RCR21071" "" 0 "" "" "HMR_7760" "MAR07769" "" "AMETt2m" "" "" "" "AMETt2m" "MNXR95811" "HMR_7769" "RCR20182" "" 0 "" "" "HMR_7769" "MAR07804" "" "DNDPt29m" "" "" "" "DNDPt29m;DNDPt10m" "MNXR97628" "HMR_7804" "RCR20121" "" 0 "" "" "HMR_7804" @@ -8394,7 +8376,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR01453" "" "HPYRR2x" "" "" "" "HPYRR2x" "MNXR100701" "" "" "" 0 "" "" "HPYRR2x" "MAR01455" "" "HRETNtn" "" "" "" "HRETNtn" "MNXR100704" "" "" "" 0 "" "" "HRETNtn" "MAR01456" "" "HSD17B42x" "" "" "" "HSD17B42x" "MNXR100718" "" "" "" 0 "" "" "HSD17B42x" -"MAR01458" "" "HSD17B4x" "" "" "" "HSD17B4x" "MNXR100720" "" "" "" 0 "" "" "HSD17B4x" "MAR01461" "" "Htr" "" "" "" "Htr" "MNXR100765" "" "" "" 0 "RHEA:34982" "RHEA:34979" "Htr" "MAR01462" "" "Htx" "" "" "" "Htx" "MNXR100765" "" "" "" 0 "RHEA:34982" "RHEA:34979" "Htx" "MAR01463" "" "HXANtl" "" "" "" "HXANtl" "MNXR100749" "" "" "" 0 "" "" "HXANtl" @@ -8983,11 +8964,9 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR03624" "" "RE3243R" "" "" "" "RE3243R" "MNXR103848" "" "" "" 0 "" "" "RE3243R" "MAR03745" "" "RE3244C" "" "" "" "RE3244C" "MNXR103849" "" "" "" 0 "" "" "RE3244C" "MAR03749" "" "RE3244R" "" "" "" "RE3244R" "MNXR103849" "" "" "" 0 "" "" "RE3244R" -"MAR03754" "" "" "" "" "" "RE3248M" "" "" "" "" 0 "" "" "RE3248M" -"MAR03756" "" "" "" "" "" "RE3248X" "" "" "" "" 0 "" "" "RE3248X" +"MAR03756" "" "" "" "" "" "RE3248X;RE3248M" "" "" "" "" 0 "" "" "RE3248X;RE3248M;MAR03754" "MAR03758" "" "RE3250C" "" "" "" "RE3250C" "MNXR103850" "" "" "" 0 "" "" "RE3250C" -"MAR03760" "" "" "" "" "" "RE3250M" "" "" "" "" 0 "" "" "RE3250M" -"MAR03764" "" "" "" "" "" "RE3250X" "" "" "" "" 0 "" "" "RE3250X" +"MAR03764" "" "" "" "" "" "RE3250X;RE3250M" "" "" "" "" 0 "" "" "RE3250X;RE3250M;MAR03760" "MAR03766" "" "RE3251C" "" "" "" "RE3251C" "MNXR103851" "" "" "" 0 "" "" "RE3251C" "MAR03768" "" "RE3251M" "" "" "" "RE3251M" "MNXR103851" "" "" "" 0 "" "" "RE3251M" "MAR03774" "" "RE3252C" "" "" "" "RE3252C" "MNXR103852" "" "" "" 0 "" "" "RE3252C" @@ -12759,7 +12738,6 @@ rxns rxnKEGGID rxnBiGGID rxnEHMNID rxnHepatoNET1ID rxnREACTOMEID rxnRecon3DID rx "MAR13061" "" "EX_M03045_e" "" "" "" "EX_M03045[e]" "" "" "" "" 0 "" "" "EX_M03045[e]" "MAR13062" "" "EX_M03051_e" "" "" "" "EX_M03051[e]" "" "" "" "" 0 "" "" "EX_M03051[e]" "MAR13063" "" "EX_M03153_e" "" "" "" "EX_M03153[e]" "" "" "" "" 0 "" "" "EX_M03153[e]" -"MAR13064" "" "" "" "" "" "EX_M01268[e]" "" "" "" "" 0 "" "" "EX_M01268[e]" "MAR13065" "" "" "" "" "" "EX_HC02080[e]" "" "" "" "" 0 "" "" "EX_HC02080[e]" "MAR13067" "" "EX_M02837_e" "" "" "" "EX_M02837[e]" "" "" "" "" 0 "" "" "EX_M02837[e]" "MAR13068" "" "" "" "" "" "EX_M02382[e]" "" "" "" "" 0 "" "" "EX_M02382[e]"