From 1eb71c613fcf4cdad4158ef5d34e6043130943bc Mon Sep 17 00:00:00 2001
From: Hao Wang <haowang.bioinfo@gmail.com>
Date: Sat, 14 Oct 2023 23:01:57 +0200
Subject: [PATCH] fix: remove MAR08564 and MAR08565

- remove MAR08564+MAR08565 that are duplicate to MAR04222
- reverse reaction direction of MAR04222
---
 model/Human-GEM.yml | 45 +++++----------------------------------------
 1 file changed, 5 insertions(+), 40 deletions(-)

diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml
index 250ee363..951ca6f4 100644
--- a/model/Human-GEM.yml
+++ b/model/Human-GEM.yml
@@ -81699,41 +81699,6 @@
       - subsystem:
           - "Tryptophan metabolism"
       - confidence_score: 0
-    - !!omap
-      - id: "MAR08564"
-      - name: ""
-      - metabolites: !!omap
-          - MAM00926c: 1
-          - MAM01306c: -1
-          - MAM01974c: 1
-          - MAM02319c: -1
-      - lower_bound: 0
-      - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000109576 or ENSG00000137944 or ENSG00000171097"
-      - rxnNotes: ""
-      - rxnFrom: "HMRdatabase"
-      - eccodes: "2.6.1.7"
-      - references: ""
-      - subsystem:
-          - "Tryptophan metabolism"
-      - confidence_score: 0
-    - !!omap
-      - id: "MAR08565"
-      - name: ""
-      - metabolites: !!omap
-          - MAM00926c: -1
-          - MAM00990c: 1
-          - MAM02040c: 1
-      - lower_bound: 0
-      - upper_bound: 1000
-      - gene_reaction_rule: ""
-      - rxnNotes: ""
-      - rxnFrom: "HMRdatabase"
-      - eccodes: ""
-      - references: ""
-      - subsystem:
-          - "Tryptophan metabolism"
-      - confidence_score: 0
     - !!omap
       - id: "MAR08566"
       - name: ""
@@ -82834,11 +82799,11 @@
       - id: "MAR04222"
       - name: ""
       - metabolites: !!omap
-          - MAM00990c: -1
-          - MAM01306c: 1
-          - MAM01974c: -1
-          - MAM02040c: -1
-          - MAM02319c: 1
+          - MAM00990c: 1
+          - MAM01306c: -1
+          - MAM01974c: 1
+          - MAM02040c: 1
+          - MAM02319c: -1
       - lower_bound: -1000
       - upper_bound: 1000
       - gene_reaction_rule: "ENSG00000109576 or ENSG00000137944 or ENSG00000171097"