From 19af535b952dae3ab24a21a87f9a3a5d18cf6d8d Mon Sep 17 00:00:00 2001 From: Mihail Anton Date: Mon, 28 Oct 2024 19:26:46 +0000 Subject: [PATCH] feat: gene essentiality workflow (#675) * feat: gene essentiality workflow with pr comment * chore: expand workflow targets * fix: add to matlab path * fix: style of macaw summary output * feat: post and store gene essentiality results * fix: model path and allow 2 workflow comments * chore: add macaw test result * fix: use recent RAVEN and gurobi * fix: avoid Penr statistic calculation * fix: missing ) in gene-essentiality.yml * chore: add gene essentiality test result * fix: gene-essentiality.yml output format * fix: location of data/testResults/README.md * chore: add macaw test result * fix: test workflow including branch update * fix: correct git-auto-commit-action@v5 * chore: add gene essentiality test result * fix: run all Hart et al. 2015 tests * fix: missing ) * chore: add gene essentiality test result * fix: only git stash pop if stash exist * fix gene-essentiality ' not " --------- Co-authored-by: Eduard Kerkhoven Co-authored-by: edkerk --- .github/workflows/commentGeneEssential.md | 7 + .github/workflows/commentMacaw.md | 9 + .github/workflows/commentsFromTests.md | 4 +- .github/workflows/gene-essentiality.yml | 80 ++++ .github/workflows/macaw-tests.yml | 21 +- code/{ => test}/estimateEssentialGenes.m | 0 code/{ => test}/evalGeneEssentialityPred.m | 0 .../{ => test}/evaluateHart2015Essentiality.m | 31 +- code/test/macawTests.py | 2 +- data/{macawResults => testResults}/README.md | 17 +- data/testResults/gene-essential.csv | 7 + .../macaw_results.csv | 418 +++++++++--------- data/testResults/macaw_summary.md | 10 + 13 files changed, 369 insertions(+), 237 deletions(-) create mode 100644 .github/workflows/commentGeneEssential.md create mode 100644 .github/workflows/commentMacaw.md create mode 100644 .github/workflows/gene-essentiality.yml rename code/{ => test}/estimateEssentialGenes.m (100%) rename code/{ => test}/evalGeneEssentialityPred.m (100%) rename code/{ => test}/evaluateHart2015Essentiality.m (88%) rename data/{macawResults => testResults}/README.md (65%) create mode 100644 data/testResults/gene-essential.csv rename data/{macawResults => testResults}/macaw_results.csv (98%) create mode 100644 data/testResults/macaw_summary.md diff --git a/.github/workflows/commentGeneEssential.md b/.github/workflows/commentGeneEssential.md new file mode 100644 index 00000000..dd2ba900 --- /dev/null +++ b/.github/workflows/commentGeneEssential.md @@ -0,0 +1,7 @@ +This PR has been [automatically tested with GH Actions](https://github.com/SysBioChalmers/Human-GEM/actions/runs/{GH_ACTION_RUN}). Here is the output of the gene essentiality test: + +
+{TEST_RESULTS}
+
+ +> _Note: In the case of multiple test runs, this post will be edited._ diff --git a/.github/workflows/commentMacaw.md b/.github/workflows/commentMacaw.md new file mode 100644 index 00000000..022ee3d0 --- /dev/null +++ b/.github/workflows/commentMacaw.md @@ -0,0 +1,9 @@ +This PR has been [automatically tested with GH Actions](https://github.com/SysBioChalmers/Human-GEM/actions/runs/{GH_ACTION_RUN}). Here is the output of the [MACAW](https://github.com/Devlin-Moyer/macaw) test: + +
+{TEST_RESULTS}
+
+ +This and a more detailed output from MACAW are also committed to `data/macawResults/`. + +> _Note: In the case of multiple test runs, this post will be edited._ diff --git a/.github/workflows/commentsFromTests.md b/.github/workflows/commentsFromTests.md index 4c5857ea..dd2ba900 100644 --- a/.github/workflows/commentsFromTests.md +++ b/.github/workflows/commentsFromTests.md @@ -1,9 +1,7 @@ -This PR has been [automatically tested with GH Actions](https://github.com/SysBioChalmers/Human-GEM/actions/runs/{GH_ACTION_RUN}). Here is the output of the macaw test: +This PR has been [automatically tested with GH Actions](https://github.com/SysBioChalmers/Human-GEM/actions/runs/{GH_ACTION_RUN}). Here is the output of the gene essentiality test: 
 {TEST_RESULTS}
-A more detailed output from this test run is also committed to `data/macawResults/macaw_results.csv`. - > _Note: In the case of multiple test runs, this post will be edited._ diff --git a/.github/workflows/gene-essentiality.yml b/.github/workflows/gene-essentiality.yml new file mode 100644 index 00000000..b92c87d6 --- /dev/null +++ b/.github/workflows/gene-essentiality.yml @@ -0,0 +1,80 @@ +name: Check gene essentiality with Hart 2015 + +on: + pull_request: + branches: + - "main" + - "develop" + +jobs: + check-metabolictasks: + runs-on: self-hosted + + steps: + - name: Checkout + uses: actions/checkout@v4 + + - name: Fetch RAVEN + uses: actions/checkout@v4 + with: + repository: "SysBioChalmers/RAVEN" + path: "RAVEN" + + - name: Run gene essentiality + id: essentiality + run: > + TEST_RESULTS=$(/usr/local/bin/matlab -batch + "warning('off', 'MATLAB:rmpath:DirNotFound'); + rmpath(genpath('/home/m/ecModels-dependencies/RAVEN')); + rmpath(genpath('/home/m/actions-runner')); + addpath(genpath('.')); + setRavenSolver('gurobi'); + ihuman = readYAMLmodel('model/Human-GEM.yml'); + taskStruct = parseTaskList('data/metabolicTasks/metabolicTasks_Essential.txt'); + [~, eGenes] = evalc('estimateEssentialGenes(ihuman, ''Hart2015_RNAseq.txt'', taskStruct);'); + output = transpose(evaluateHart2015Essentiality(eGenes)); + fid = fopen('data/testResults/gene-essential.csv','w'); + fprintf(fid,[repmat('%s,',1,9) '%s\n'],output{:,1}); + fprintf(fid,['%s,%d,%d,%d,%d' repmat(',%.4g',1,5) '\n'],output{:,2:end}); + fclose(fid); + disp(cell2table(transpose(output(:,2:end)),'VariableNames',output(:,1)));") && + echo "$TEST_RESULTS" && + PARSED_RESULTS="${TEST_RESULTS//$'\n'/'
'}" && + PARSED_RESULTS="${PARSED_RESULTS//$'\r'/'
'}" && + echo "results=$PARSED_RESULTS" >> $GITHUB_OUTPUT + + - name: Mention PR# in README.md + env: + PR_NUMBER: ${{ github.event.number }} + run: sed -i -e "s/[[:digit:]]\{3,4\}\*\* (gene /$PR_NUMBER\*\* (gene /" data/testResults/README.md + + - name: Update local branch before committing changes + env: + BRANCH_NAME: ${{ github.head_ref || github.ref_name }} + run: | + git stash + git fetch + git checkout $BRANCH_NAME + if git stash list | grep -q 'stash@{'; then + git stash pop + fi + + - name: Auto-commit results + uses: stefanzweifel/git-auto-commit-action@v5 + with: + commit_user_name: memote-bot + commit_message: "chore: add gene essentiality test result" + file_pattern: data/testResults/* + env: + GITHUB_TOKEN: ${{ secrets.GITHUB_TOKEN }} + PR_NUMBER: ${{ github.event.number }} + + - name: Post comment + uses: NejcZdovc/comment-pr@v2 + with: + file: "commentGeneEssential.md" + identifier: "GITHUB_COMMENT_GENE" + env: + GITHUB_TOKEN: ${{secrets.GITHUB_TOKEN}} + TEST_RESULTS: ${{steps.essentiality.outputs.results}} + GH_ACTION_RUN: ${{github.run_id}} diff --git a/.github/workflows/macaw-tests.yml b/.github/workflows/macaw-tests.yml index 90af0ee7..be78f38d 100644 --- a/.github/workflows/macaw-tests.yml +++ b/.github/workflows/macaw-tests.yml @@ -31,18 +31,30 @@ jobs: PARSED_RESULTS="${PARSED_RESULTS//$'\r'/'
'}" echo $PARSED_RESULTS echo "results=$PARSED_RESULTS" >> $GITHUB_OUTPUT + printf "$TEST_RESULTS" > data/testResults/macaw_summary.md - name: Mention PR# in README.md env: PR_NUMBER: ${{ github.event.number }} - run: sed -i -e "s/#[[:digit:]]\{3,4\}/#$PR_NUMBER/g" data/macawResults/README.md - + run: sed -i -e "s/[[:digit:]]\{3,4\}\*\* (MACAW)/$PR_NUMBER\*\* (MACAW)/" data/testResults/README.md + + - name: Update local branch before committing changes + env: + BRANCH_NAME: ${{ github.head_ref || github.ref_name }} + run: | + git stash + git fetch + git checkout $BRANCH_NAME + if git stash list | grep -q 'stash@{'; then + git stash pop + fi + - name: Auto-commit results uses: stefanzweifel/git-auto-commit-action@v4 with: commit_user_name: memote-bot commit_message: "chore: add macaw test result" - file_pattern: data/macawResults/* + file_pattern: data/testResults/* env: GITHUB_TOKEN: ${{ secrets.GITHUB_TOKEN }} PR_NUMBER: ${{ github.event.number }} @@ -50,7 +62,8 @@ jobs: - name: Post comment uses: NejcZdovc/comment-pr@v2 with: - file: "commentsFromTests.md" + file: "commentMacaw.md" + identifier: "GITHUB_COMMENT_MACAW" env: GITHUB_TOKEN: ${{secrets.GITHUB_TOKEN}} TEST_RESULTS: ${{steps.macaw-run.outputs.results}} diff --git a/code/estimateEssentialGenes.m b/code/test/estimateEssentialGenes.m similarity index 100% rename from code/estimateEssentialGenes.m rename to code/test/estimateEssentialGenes.m diff --git a/code/evalGeneEssentialityPred.m b/code/test/evalGeneEssentialityPred.m similarity index 100% rename from code/evalGeneEssentialityPred.m rename to code/test/evalGeneEssentialityPred.m diff --git a/code/evaluateHart2015Essentiality.m b/code/test/evaluateHart2015Essentiality.m similarity index 88% rename from code/evaluateHart2015Essentiality.m rename to code/test/evaluateHart2015Essentiality.m index 1ae32aa8..8fd1cb02 100644 --- a/code/evaluateHart2015Essentiality.m +++ b/code/test/evaluateHart2015Essentiality.m @@ -31,16 +31,16 @@ % Table S2 from the Hart2015 datasets: % In this study, essential genes are, by definition, a subset of fitness genes x = readtable('Hart2015_TableS2.xlsx'); - + % remove duplicated rows (MARCH1 and MARCH2 genes) ind1 = find(ismember(x.Gene,'MARCH1'),1,'last'); ind2 = find(ismember(x.Gene,'MARCH2'),1,'last'); x([ind1;ind2],:) = []; - + % extract gene list and cell types genes = x.Gene; celltypes = regexprep(upper(x.Properties.VariableNames(3:7)'),'BF_',''); - + % for each cell type, determine the "fitness" genes, defined as those with % a 5% FDRs were chosen as thresholds (the values are extracted from the % supporting information of the Hart 2015 paper. Genes observed in 3 or more @@ -63,7 +63,7 @@ % also get the genes that were essential in all 5 cell lines ("all") celltypes(end+1) = {'all'}; fitness_mat(:,end+1) = all(fitness_mat == 1,2); - + % put Hart2015 essentiality data into data structure for comparison expdata = {}; expdata.genes = genes; @@ -94,12 +94,12 @@ % calculate true and false positives and negatives [TP,TN,FP,FN,Penr] = deal(nan(numel(tissues),1)); % initialize variables for i = 1:numel(tissues) - + [~,tissue_ind] = ismember(tissues(i), expdata.tissues); if tissue_ind == 0 continue % a few tissues are missing from the DepMap dataset end - + modelGenes = eGenes.refModel.genes; if strcmpi(tissues{i},'all') modelEssential = modelGenes(sum(modelPred,2) == size(modelPred,2)); @@ -107,17 +107,18 @@ modelEssential = modelGenes(modelPred(:,i)); end modelNonEssential = setdiff(modelGenes,modelEssential); - + expGenes = expdata.genes(~isnan(expdata.essential(:,tissue_ind))); expEssential = expdata.genes(expdata.essential(:,tissue_ind) == 1); expNonEssential = setdiff(expGenes,expEssential); - + TP(i) = sum(ismember(modelEssential, expEssential)); % true positives TN(i) = sum(ismember(modelNonEssential, expNonEssential)); % true negatives FP(i) = sum(ismember(modelEssential, expNonEssential)); % false positives - FN(i) = sum(ismember(modelNonEssential, expEssential)); % false negatives + FN(i) = sum(ismember(modelNonEssential, expEssential)); % false negatives - Penr(i) = EnrichmentTest(intersect(modelGenes,expGenes), intersect(modelEssential,expGenes), intersect(expEssential,modelGenes)); + % Requires Statistics and Machine Learning Toolbox + %Penr(i) = EnrichmentTest(intersect(modelGenes,expGenes), intersect(modelEssential,expGenes), intersect(expEssential,modelGenes)); end % calculate some metrics @@ -126,13 +127,15 @@ accuracy = (TP + TN)./(TP + TN + FP + FN); F1 = 2*TP./(2*TP + FP + FN); MCC = ((TP.*TN) - (FP.*FN))./sqrt((TP+FP).*(TP+FN).*(TN+FP).*(TN+FN)); % Matthews correlation coefficient -PenrAdj = adjust_pvalues(Penr,'Benjamini'); +%PenrAdj = adjust_pvalues(Penr,'Benjamini'); % get results for cell types -results = [{'cellLine','TP','TN','FP','FN','accuracy','sensitivity','specificity','F1','MCC','Penr','logPenr','PenrAdj','logPenrAdj'}; - [tissues, num2cell([TP, TN, FP, FN, accuracy, sensitivity, specificity, F1, MCC, Penr, -log10(Penr), PenrAdj, -log10(PenrAdj)])]]; - +results = [{'cellLine','TP','TN','FP','FN','accuracy','sensitivity','specificity','F1','MCC'}; + [tissues, num2cell([TP, TN, FP, FN, accuracy, sensitivity, specificity, F1, MCC])]]; +% Including Penr results +%results = [{'cellLine','TP','TN','FP','FN','accuracy','sensitivity','specificity','F1','MCC','Penr','logPenr','PenrAdj','logPenrAdj'}; +% [tissues, num2cell([TP, TN, FP, FN, accuracy, sensitivity, specificity, F1, MCC, Penr, -log10(Penr), PenrAdj, -log10(PenrAdj)])]]; end function [penr,pdep] = EnrichmentTest(pop,sample,successes) diff --git a/code/test/macawTests.py b/code/test/macawTests.py index 92f71544..7b285639 100644 --- a/code/test/macawTests.py +++ b/code/test/macawTests.py @@ -5,4 +5,4 @@ (dead_end_results, dead_end_edges) = dead_end_test(model) (duplicate_results, duplicate_edges) = duplicate_test(model) output = dead_end_results.merge(duplicate_results) -output.to_csv('data/macawResults/macaw_results.csv', index = False) \ No newline at end of file +output.to_csv('data/testResults/macaw_results.csv', index = False) \ No newline at end of file diff --git a/data/macawResults/README.md b/data/testResults/README.md similarity index 65% rename from data/macawResults/README.md rename to data/testResults/README.md index 411815dd..5b0034ab 100644 --- a/data/macawResults/README.md +++ b/data/testResults/README.md @@ -1,13 +1,13 @@ -# MACAW results +# Test results -The file here contains results from the [MACAW](https://github.com/Devlin-Moyer/macaw) `dead_end_test` and `duplicate_test` tests. +The file here contains results from the [MACAW](https://github.com/Devlin-Moyer/macaw) `dead_end_test` and `duplicate_test` tests, and from cell-line specific gene essentiality prediction based on the [Hart _et al._ (2015)](https://doi.org/10.1016/j.cell.2015.11.015) dataset. -The test results shown here were obtained by the GitHub Actions run in **PR #829**, and will be updated by any subsequent PR. Summary results are shown as a comment in the corresponding PR. +The test results shown here were obtained by the GitHub Actions run in **PR #675** (MACAW) and **PR #675** (gene essentiality), and will be updated by any subsequent PR. Summary results are shown as a comment in the corresponding PR. -### `dead_end_test` +### MACAW: `dead_end_test` Looks for metabolites in Human-GEM that can only be produced by all reactions they participate in or only consumed, then identifies all reactions that are prevented from sustaining steady-state fluxes because of each of these dead-end metabolites. The simplest case of a dead-end metabolite is one that only participates in a single reaction. Also flags all reversible reactions that can only carry fluxes in a single direction because one of their metabolites can either only be consumed or only be produced by all other reactions it participates in. -### `duplicate_test` +### MACAW: `duplicate_test` Identifies sets of reactions that may be duplicates of each other because they: - Involve exactly the same metabolites with exactly the same stoichiometric coefficients (but potentially different associated genes). @@ -15,4 +15,9 @@ Identifies sets of reactions that may be duplicates of each other because they: - Involve exactly the same metabolites, but with different stoichiometric coefficients. - Represent the oxidation and/or reduction of the same metabolite, but use different electron acceptors/donors from the given list of pairs of oxidized and reduced forms of various electron carriers (e.g. NAD(H), NADP(H), FAD(H2), ubiquinone/ubiquinol, cytochromes). -It is possible for a single reaction to fit in multiple of the above categories. There are sometimes cases where sets of reactions that fall into one of the above categories are completely legitimate representations of real biochemistry (e.g. separate irreversible reactions for importing vs exporting the same metabolite because two different transporters encoded by different genes are each responsible for transporting that metabolite in only one direction, enzymes that can use NAD(H) or NADP(H) interchangeably to catalyze the same redox reaction), but reactions that meet these criteria are generally worth close examination to ensure that they should actually all exist as separate reactions. \ No newline at end of file +It is possible for a single reaction to fit in multiple of the above categories. There are sometimes cases where sets of reactions that fall into one of the above categories are completely legitimate representations of real biochemistry (e.g. separate irreversible reactions for importing vs exporting the same metabolite because two different transporters encoded by different genes are each responsible for transporting that metabolite in only one direction, enzymes that can use NAD(H) or NADP(H) interchangeably to catalyze the same redox reaction), but reactions that meet these criteria are generally worth close examination to ensure that they should actually all exist as separate reactions. + +### Cell-line specific gene essentiality +Evaluate gene essentiality predictions in 5 cell-line specific GEMs with experimental fitness data gathered from the [Hart _et al._ (2015)](https://doi.org/10.1016/j.cell.2015.11.015). + +Cell-line specific GEMs are constructed with tINIT2 for DLD1, GBM, HCT116, HeLa and RPE1 cell lines. Then, the `metabolicTasks_Essential.txt` list of tasks is used to identify essential genes in each of these models. The predicted gene essentiality is compared to results from a high-throughput CRISPR-Cas9 screen for identifying genes that affect fitness. Only the summary statistics of this comparison are kept. \ No newline at end of file diff --git a/data/testResults/gene-essential.csv b/data/testResults/gene-essential.csv new file mode 100644 index 00000000..7a3cef63 --- /dev/null +++ b/data/testResults/gene-essential.csv @@ -0,0 +1,7 @@ +cellLine,TP,TN,FP,FN,accuracy,sensitivity,specificity,F1,MCC +DLD1,36,2185,59,279,0.8679,0.1143,0.9737,0.1756,0.1529 +GBM,34,2165,61,298,0.8597,0.1024,0.9726,0.1593,0.1333 +HCT116,46,2207,53,309,0.8616,0.1296,0.9765,0.2026,0.1905 +HELA,30,2263,69,254,0.8765,0.1056,0.9704,0.1567,0.124 +RPE1,14,2204,81,259,0.8671,0.05128,0.9646,0.07609,0.02585 +all,7,2408,92,109,0.9232,0.06034,0.9632,0.06512,0.0254 diff --git a/data/macawResults/macaw_results.csv b/data/testResults/macaw_results.csv similarity index 98% rename from data/macawResults/macaw_results.csv rename to data/testResults/macaw_results.csv index 716de677..aa73eeed 100644 --- a/data/macawResults/macaw_results.csv +++ b/data/testResults/macaw_results.csv @@ -1,6 +1,6 @@ reaction_id,reaction_equation,dead_end_test,duplicate_test_exact,duplicate_test_directions,duplicate_test_coefficients,duplicate_test_redox -MAR03905,MAM01796c + MAM02552c --> MAM01249c + MAM02039c + MAM02553c,ok,ok,ok,ok,N/A -MAR03907,MAM01796c + MAM02554c --> MAM01249c + MAM02039c + MAM02555c,ok,ok,ok,ok,N/A +MAR03905,MAM01796c + MAM02552c --> MAM01249c + MAM02039c + MAM02553c,MAM01796c,ok,ok,ok,N/A +MAR03907,MAM01796c + MAM02554c --> MAM01249c + MAM02039c + MAM02555c,MAM01796c,ok,ok,ok,N/A MAR04097,MAM01252c + MAM01371c + MAM01597c --> MAM01261c + MAM01334c + MAM02759c,ok,ok,ok,ok,N/A MAR04099,MAM01252m + MAM01371m + MAM01597m --> MAM01261m + MAM01334m + MAM02759m,ok,ok,ok,ok,N/A MAR04108,MAM01257c + MAM01597c --> MAM01261c + MAM01334c + MAM02039c,ok,ok,ok,ok,N/A @@ -31,9 +31,9 @@ MAR04521,MAM01968r + MAM02040r --> MAM01965r + MAM02751r,ok,ok,ok,ok,N/A MAR06412,MAM01597m + MAM02869m --> MAM01261m + MAM01701m,ok,ok,ok,ok,N/A MAR07745,MAM01388c <=> MAM01965c,MAM01388c,ok,ok,ok,N/A MAR07747,MAM01285c + MAM01965c --> MAM01334c + MAM01968c + MAM02039c,ok,ok,ok,ok,N/A -MAR08360,MAM01796x + MAM02041x --> MAM01249x + 2 MAM02040x,ok,ok,ok,ok,N/A +MAR08360,MAM01796x + MAM02041x --> MAM01249x + 2 MAM02040x,MAM01249x;MAM01796x,ok,ok,ok,N/A MAR08652,MAM01420r + MAM01965r --> MAM01596r + MAM01968r + MAM02578r,MAM01420r;MAM02578r,ok,ok,ok,N/A -MAR08757,MAM01796c + MAM02039c + MAM02555c + MAM02630c --> MAM01249c + 2 MAM02040c + MAM02554c,ok,ok,ok,ok,N/A +MAR08757,MAM01796c + MAM02039c + MAM02555c + MAM02630c --> MAM01249c + 2 MAM02040c + MAM02554c,MAM01796c,ok,ok,ok,N/A MAR03989,MAM02040e + MAM02450e --> 2 MAM01965e,ok,ok,ok,ok,N/A MAR04122,MAM02040c + 2 MAM02552c + MAM03108c --> 3 MAM02039c + 2 MAM02553c + MAM03109c,ok,ok,ok,ok,N/A MAR04837,MAM02040e + MAM03039e --> 2 MAM01965e,ok,ok,ok,ok,N/A @@ -45,15 +45,15 @@ MAR05398,MAM01992c + 3 MAM02751c --> 3 MAM01967c + MAM01991c,ok,ok,ok,ok,N/A MAR05399,MAM01991c --> MAM01994c,ok,ok,ok,ok,N/A MAR05400,MAM01994c + MAM02040c --> MAM01965c + MAM01993c,ok,ok,ok,ok,N/A MAR05401,MAM01993c + 7 MAM02751c --> 7 MAM01967c + MAM01996c,ok,ok,ok,ok,N/A -MAR08568,MAM02040c + MAM02445c --> MAM01840c + MAM02448c,ok,ok,ok,ok,N/A -MAR08569,MAM02040e + MAM02445e --> MAM01965e + MAM02448e,ok,ok,ok,ok,N/A -MAR08570,2 MAM02040c + MAM02448c --> 2 MAM01840c + MAM02446c,ok,ok,ok,ok,N/A -MAR08571,2 MAM02040e + MAM02448e --> 2 MAM01965e + MAM02446e,ok,ok,ok,ok,N/A -MAR08572,MAM02040c + MAM02446c --> MAM01840c + MAM02447c,ok,ok,ok,ok,N/A +MAR08568,MAM02040c + MAM02445c --> MAM01840c + MAM02448c,MAM02445c;MAM02448c,ok,ok,ok,N/A +MAR08569,MAM02040e + MAM02445e --> MAM01965e + MAM02448e,MAM02445e;MAM02448e,ok,ok,ok,N/A +MAR08570,2 MAM02040c + MAM02448c --> 2 MAM01840c + MAM02446c,MAM02446c;MAM02448c,ok,ok,ok,N/A +MAR08571,2 MAM02040e + MAM02448e --> 2 MAM01965e + MAM02446e,MAM02448e,ok,ok,ok,N/A +MAR08572,MAM02040c + MAM02446c --> MAM01840c + MAM02447c,MAM02446c;MAM02447c,ok,ok,ok,N/A MAR08573,MAM02040e + MAM02446e --> MAM01965e + MAM02447e,ok,ok,ok,ok,N/A -MAR08574,MAM02040c + MAM02447c --> MAM01840c + MAM02449c,ok,ok,ok,ok,N/A +MAR08574,MAM02040c + MAM02447c --> MAM01840c + MAM02449c,MAM02447c;MAM02449c,ok,ok,ok,N/A MAR08575,MAM02040e + MAM02447e --> MAM01965e + MAM02449e,ok,ok,ok,ok,N/A -MAR08576,MAM02040c + MAM02449c --> MAM01840c + MAM02451c,ok,ok,ok,ok,N/A +MAR08576,MAM02040c + MAM02449c --> MAM01840c + MAM02451c,MAM02449c,ok,ok,ok,N/A MAR08577,MAM02040e + MAM02449e --> MAM01965e + MAM02451e,ok,ok,ok,ok,N/A MAR08578,MAM02040c + MAM02451c --> MAM01840c + MAM02452c,ok,ok,ok,ok,N/A MAR08579,MAM02040e + MAM02451e --> MAM01965e + MAM02452e,ok,ok,ok,ok,N/A @@ -112,12 +112,12 @@ MAR04592,MAM01758c + MAM02039c + MAM02555c <=> MAM02554c + MAM03155c,ok,ok,ok,ok MAR04593,MAM02552c + MAM03155c --> MAM01759c + MAM02039c + MAM02553c,ok,ok,ok,ok,N/A MAR04594,MAM01758c + MAM02554c --> MAM01757c + MAM02039c + MAM02555c,MAM01757c,ok,ok,ok,N/A MAR04595,MAM01285c + MAM01761c + MAM02039c <=> MAM01371c + MAM01759c,ok,ok,ok,ok,N/A -MAR08341,MAM02039c + MAM02337c + MAM02555c --> MAM02338c + MAM02554c,ok,ok,ok,ok,N/A -MAR08342,MAM02039c + MAM02425c + MAM02553c <=> MAM02338c + MAM02552c,ok,ok,ok,ok,N/A +MAR08341,MAM02039c + MAM02337c + MAM02555c --> MAM02338c + MAM02554c,MAM02337c,ok,ok,ok,N/A +MAR08342,MAM02039c + MAM02425c + MAM02553c <=> MAM02338c + MAM02552c,only when going backwards,ok,ok,ok,N/A MAR08344,MAM01973r + MAM02039r + MAM02555r <=> MAM02378r + MAM02554r,ok,ok,ok,ok,N/A MAR08352,MAM00768c + MAM02039c + MAM02553c <=> MAM02378c + MAM02552c,ok,ok,ok,ok,N/A MAR08353,MAM00768c + MAM02039c <=> MAM01596c + MAM02425c,ok,ok,ok,ok,N/A -MAR08726,MAM01371c + MAM01743c --> MAM01285c + MAM02039c + MAM02846c,ok,ok,ok,ok,N/A +MAR08726,MAM01371c + MAM01743c --> MAM01285c + MAM02039c + MAM02846c,MAM01743c,ok,ok,ok,N/A MAR08727,MAM02040c + MAM03109c --> MAM01684c + 2 MAM02039c + MAM03114c,ok,ok,ok,ok,N/A MAR08728,MAM01684c + MAM02040c --> MAM01973c + MAM02751c,ok,ok,ok,ok,N/A MAR08729,MAM02040c + MAM03109c --> MAM01973c + MAM02039c + MAM03106c,ok,ok,ok,ok,N/A @@ -376,7 +376,7 @@ MAR06624,MAM01673m + MAM01688m --> MAM01680m + MAM01755m + MAM02039m,ok,ok,ok,ok MAR06627,MAM01747c + MAM02039c + MAM02696c <=> MAM01753c + MAM02819c,ok,ok,ok,ok,N/A MAR07744,MAM02040c + MAM02807c <=> MAM02845c + MAM03118c,MAM02807c,ok,ok,ok,N/A MAR08072,MAM00639c + MAM02040c --> MAM01672c + MAM02751c,ok,ok,ok,ok,N/A -MAR08637,MAM01632c + MAM02040c --> MAM02578c + MAM03118c,ok,ok,ok,ok,N/A +MAR08637,MAM01632c + MAM02040c --> MAM02578c + MAM03118c,MAM01632c,ok,ok,ok,N/A MAR03965,MAM01754c + MAM02040c --> MAM01755c + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A MAR03966,MAM01371m + MAM02040m --> MAM01334m + MAM02039m + MAM02759m,ok,ok,ok,ok,N/A MAR03967,MAM01424c + MAM01948c <=> MAM01590c + MAM02034c,ok,ok,ok,ok,N/A @@ -454,8 +454,8 @@ MAR07895,MAM01285m + MAM02193m <=> MAM01371m + MAM02161m,ok,ok,ok,ok,N/A MAR08083,MAM01433n + MAM02040n --> MAM02016n + MAM02039n,ok,ok,ok,ok,N/A MAR08085,MAM01433g + MAM02040g --> MAM02016g + MAM02039g,ok,ok,ok,ok,N/A MAR08087,MAM01419g + MAM02040g --> MAM01334g + MAM02039g,ok,ok,ok,ok,N/A -MAR08443,MAM01286c + MAM02040c --> MAM01334c + MAM01967c + 2 MAM02039c,ok,ok,ok,ok,N/A -MAR08444,MAM01287c + MAM02040c --> MAM01334c + 2 MAM02039c + MAM02454c,ok,ok,ok,ok,N/A +MAR08443,MAM01286c + MAM02040c --> MAM01334c + MAM01967c + 2 MAM02039c,MAM01286c,ok,ok,ok,N/A +MAR08444,MAM01287c + MAM02040c --> MAM01334c + 2 MAM02039c + MAM02454c,MAM01287c,ok,ok,ok,N/A MAR08445,MAM01371m + MAM01630m --> MAM01285m + MAM01590m + MAM02039m,ok,ok,ok,ok,N/A MAR08446,MAM01630n + MAM02040n --> MAM02578n + MAM03123n,ok,ok,ok,ok,N/A MAR08448,MAM01424c + MAM01680c <=> MAM01590c + MAM01688c,ok,ok,ok,ok,N/A @@ -496,7 +496,7 @@ MAR08484,MAM01371m + MAM02170m --> MAM01285m + MAM02039m + MAM02167m,ok,ok,ok,ok MAR08485,MAM02040g + MAM03106g --> MAM02039g + MAM02751g + MAM03114g,ok,ok,ok,ok,N/A MAR08486,MAM01280c + MAM02751c <=> MAM01279c + MAM02844c,ok,ok,ok,ok,N/A MAR08487,MAM02040e + MAM03114e --> MAM02751e + MAM03123e,ok,ok,ok,ok,N/A -MAR08488,MAM02040c + MAM03154c --> MAM02039c + MAM02759c + MAM03150c,ok,ok,ok,ok,N/A +MAR08488,MAM02040c + MAM03154c --> MAM02039c + MAM02759c + MAM03150c,MAM03154c,ok,ok,ok,N/A MAR08489,MAM02040c + MAM02193c --> MAM02039c + MAM02167c + MAM02759c,ok,ok,ok,ok,N/A MAR08493,MAM01644l + MAM02040l --> MAM01668l + MAM02751l,MAM01644l;MAM01668l,ok,ok,ok,N/A MAR08494,MAM01639l + MAM02040l --> MAM01666l + MAM02751l,MAM01639l;MAM01666l,ok,ok,ok,N/A @@ -1043,7 +1043,7 @@ MAR07141,MAM02040c + MAM02895c --> MAM02039c + MAM02469c + MAM02578c + MAM02819c MAR07620,MAM01371c + MAM02891c + MAM03075c --> MAM01334c + MAM02759c + MAM02893c,MAM02893c,ok,ok,ok,N/A MAR07647,MAM01638x + MAM01802x + MAM02040x --> MAM01803x + MAM02039x + MAM02578x + MAM02819x,ok,ok,ok,ok,N/A MAR08640,MAM01721n + MAM02882n --> MAM01722n + MAM02039n + MAM02881n,MAM02881n;MAM02882n,ok,ok,ok,N/A -MAR08689,MAM01640x + MAM01802x + MAM02040x --> MAM01101x + MAM01803x + MAM02039x + MAM02578x,ok,ok,ok,ok,N/A +MAR08689,MAM01640x + MAM01802x + MAM02040x --> MAM01101x + MAM01803x + MAM02039x + MAM02578x,MAM01101x;MAM01640x,ok,ok,ok,N/A MAR08690,MAM01740x + MAM01802x + MAM02040x --> MAM01073x + MAM01803x + MAM02039x + MAM02578x,ok,ok,ok,ok,N/A MAR03753,MAM02040m + MAM02468m --> MAM00785m,ok,ok,ok,ok,N/A MAR03755,MAM00785m + MAM02040m --> MAM00784m + MAM01597m + MAM02039m,ok,ok,ok,ok,N/A @@ -1057,8 +1057,8 @@ MAR03792,MAM00661m + MAM01974m <=> MAM01306m + MAM01633m,ok,ok,ok,ok,N/A MAR03796,MAM01334m + MAM02039m + MAM02774m <=> MAM01597m + MAM02775m,only when going forwards,ok,ok,ok,N/A MAR03823,MAM00171m + MAM02552m <=> MAM00662m + MAM02039m + MAM02553m,only when going backwards,ok,ok,ok,N/A MAR06416,MAM02393m + MAM20078m --> MAM02857m + MAM02984m,ok,ok,ok,ok,N/A -MAR03986,2 MAM01438e + MAM02040e --> MAM01439e,ok,ok,ok,ok,N/A -MAR03988,MAM01439l + MAM02040l --> 2 MAM02527l,ok,ok,ok,ok,N/A +MAR03986,2 MAM01438e + MAM02040e --> MAM01439e,MAM01438e;MAM01439e,ok,ok,ok,N/A +MAR03988,MAM01439l + MAM02040l --> 2 MAM02527l,MAM01439l,ok,ok,ok,N/A MAR04124,MAM02039r + MAM03109r --> MAM01596r + MAM03112r,ok,ok,ok,ok,N/A MAR04158,MAM02039c + MAM02528c + MAM03130c --> MAM02759c + MAM03111c,ok,ok,ok,ok,N/A MAR04159,MAM03110c <=> MAM03111c,ok,ok,ok,ok,N/A @@ -1089,8 +1089,8 @@ MAR08368,MAM02039c + MAM02526c + MAM03130c --> MAM02759c + MAM03110c,ok,ok,ok,ok MAR08371,MAM02040c + MAM02455c + MAM02696c --> MAM00772c + MAM02751c,ok,ok,ok,ok,N/A MAR08372,MAM00772c + MAM02040c --> MAM00771c + MAM02751c,ok,ok,ok,ok,N/A MAR08373,MAM02524c + MAM02819c <=> MAM02543c,ok,ok,ok,ok,N/A -MAR08375,MAM01438c + MAM02040c --> MAM02527c,ok,ok,ok,ok,N/A -MAR08376,MAM01438e + MAM02040e --> MAM02527e,ok,ok,ok,ok,N/A +MAR08375,MAM01438c + MAM02040c --> MAM02527c,MAM01438c,ok,ok,ok,N/A +MAR08376,MAM01438e + MAM02040e --> MAM02527e,MAM01438e;MAM02527e,ok,ok,ok,N/A MAR08377,MAM01623c + MAM02543c --> MAM01592c + MAM02759c,ok,ok,ok,ok,N/A MAR08672,MAM02039g + MAM03109g --> MAM01596g + MAM03112g,MAM01596g;MAM03112g,ok,ok,ok,N/A MAR08674,MAM00946c --> MAM01748c,MAM00946c;MAM01748c,ok,ok,ok,N/A @@ -2579,9 +2579,9 @@ MAR03370,MAM02040x + MAM03023x --> MAM01574x,ok,ok,ok,ok,N/A MAR03372,MAM01574x + MAM02552x --> MAM00886x + MAM02039x + MAM02553x,ok,ok,ok,ok,N/A MAR03373,MAM00886x + MAM01597x --> MAM00099x + MAM01261x,ok,ok,ok,ok,N/A MAR03375,MAM00042x <=> MAM00099x,only when going forwards,ok,ok,ok,N/A -MAR03478,MAM02746c --> MAM02746x,ok,ok,ok,ok,N/A -MAR03480,MAM01371c + MAM01597c + MAM02746c --> MAM01334c + MAM02747c + MAM02759c,ok,ok,ok,ok,N/A -MAR03481,MAM01371c + 2 MAM02040c + MAM02747c <=> MAM01285c + MAM01597c + 2 MAM02039c + MAM02746x + MAM02751c,only when going backwards,ok,ok,ok,N/A +MAR03478,MAM02746c --> MAM02746x,MAM02746c,ok,ok,ok,N/A +MAR03480,MAM01371c + MAM01597c + MAM02746c --> MAM01334c + MAM02747c + MAM02759c,MAM02746c;MAM02747c,ok,ok,ok,N/A +MAR03481,MAM01371c + 2 MAM02040c + MAM02747c <=> MAM01285c + MAM01597c + 2 MAM02039c + MAM02746x + MAM02751c,MAM02747c,ok,ok,ok,N/A MAR03482,MAM01371x + MAM01597x + MAM02746x --> MAM01334x + MAM02747x + MAM02759x,ok,ok,ok,ok,N/A MAR03484,MAM01306x + MAM02630x + MAM02747x --> MAM00655x + MAM01596x + MAM02943x,ok,ok,ok,ok,N/A MAR03486,MAM00655x --> MAM01836x + MAM20083x,ok,ok,ok,ok,N/A @@ -3604,37 +3604,37 @@ MAR00921,MAM01430r + MAM03107r --> MAM01679r + MAM02039r + MAM03106r,ok,ok,ok,ok MAR00924,MAM01679c + MAM03107c --> MAM01694c + MAM02039c + MAM03106c,ok,ok,ok,ok,N/A MAR00925,MAM01679g + MAM03107g --> MAM01694g + MAM02039g + MAM03106g,ok,ok,ok,ok,N/A MAR00926,MAM01972c + MAM03107c --> MAM02039c + MAM02328c + MAM03106c,ok,ok,ok,ok,N/A -MAR07188,MAM01143r + MAM02040r --> MAM01142r + 2 MAM02039r + MAM02730r,MAM01142r,ok,ok,ok,N/A +MAR07188,MAM01143r + MAM02040r --> MAM01142r + 2 MAM02039r + MAM02730r,MAM01142r;MAM01143r,ok,ok,ok,N/A MAR08378,MAM01733c + MAM02039c + MAM02645c <=> MAM00205c + MAM01734c,MAM02645c,ok,ok,ok,N/A -MAR08379,MAM02750c + MAM03111c --> MAM02039c + MAM02523c + MAM03106c,ok,ok,ok,ok,N/A -MAR07185,MAM02750r + MAM03111r --> MAM02039r + MAM02523r + MAM03106r,ok,ok,ok,ok,N/A -MAR08380,MAM02040c + MAM02523c --> MAM01143c + MAM01252c,ok,ok,ok,ok,N/A -MAR07186,MAM02040r + MAM02523r --> MAM01143r + MAM01252r,ok,ok,ok,ok,N/A -MAR08381,MAM01143c + MAM02678c --> MAM01597c + MAM01964c,ok,ok,ok,ok,N/A -MAR07187,MAM01143r + MAM02678r --> MAM01597r + MAM01964r,ok,ok,ok,ok,N/A -MAR08383,MAM01734r + MAM01964r --> MAM01733r + MAM02039r + MAM02483r,ok,ok,ok,ok,N/A -MAR08384,MAM01734r + MAM02483r --> MAM01733r + MAM02039r + MAM02431r,ok,ok,ok,ok,N/A -MAR08385,MAM01734r + MAM02431r --> MAM01733r + MAM02039r + MAM02433r,ok,ok,ok,ok,N/A -MAR08387,MAM01734r + MAM01783r --> MAM01733r + MAM02039r + MAM02463r,ok,ok,ok,ok,N/A -MAR08388,MAM01734r + MAM02463r --> MAM01733r + MAM02039r + MAM02430r,ok,ok,ok,ok,N/A -MAR08389,MAM01734r + MAM02430r --> MAM01733r + MAM02039r + MAM02432r,ok,ok,ok,ok,N/A -MAR08390,MAM01734r + MAM01779r --> MAM01733r + MAM02039r + MAM02461r,ok,ok,ok,ok,N/A -MAR08391,MAM02483r + MAM02685r --> MAM00236r + MAM01783r,ok,ok,ok,ok,N/A -MAR08392,MAM02431r + MAM02685r --> MAM00236r + MAM02463r,ok,ok,ok,ok,N/A -MAR08393,MAM02433r + MAM02685r --> MAM00236r + MAM01781r,ok,ok,ok,ok,N/A -MAR08394,MAM02433r + MAM02685r --> MAM00236r + MAM02430r,ok,ok,ok,ok,N/A -MAR08395,MAM01781r + MAM02685r --> MAM00236r + MAM01782r,ok,ok,ok,ok,N/A -MAR08396,MAM02430r + MAM02685r --> MAM00236r + MAM01779r,ok,ok,ok,ok,N/A -MAR08397,MAM01781r + MAM02685r --> MAM00236r + MAM01779r,ok,ok,ok,ok,N/A -MAR08398,MAM01779r + MAM02685r --> MAM00236r + MAM02020r,ok,ok,ok,ok,N/A -MAR08399,MAM01782r + MAM02685r --> MAM00236r + MAM02020r,ok,ok,ok,ok,N/A -MAR08401,MAM02432r + MAM02685r --> MAM00236r + MAM02461r,ok,ok,ok,ok,N/A -MAR08402,MAM01779r + MAM02001r --> MAM01780r + MAM02022r,ok,ok,ok,ok,N/A -MAR08403,MAM01780r + MAM02040r --> MAM01665r + MAM02039r + MAM02674r,ok,ok,ok,ok,N/A -MAR08404,MAM02001r + MAM02020r --> MAM02021r + MAM02022r,ok,ok,ok,ok,N/A -MAR08405,MAM02021r + MAM02040r --> MAM01687r + MAM02039r + MAM02674r,ok,ok,ok,ok,N/A -MAR08406,MAM02001r + MAM02433r --> MAM02022r + MAM02434r,ok,ok,ok,ok,N/A -MAR08407,MAM02001r + MAM02461r --> MAM02022r + MAM02462r,ok,ok,ok,ok,N/A +MAR08379,MAM02750c + MAM03111c --> MAM02039c + MAM02523c + MAM03106c,MAM02523c,ok,ok,ok,N/A +MAR07185,MAM02750r + MAM03111r --> MAM02039r + MAM02523r + MAM03106r,MAM02523r,ok,ok,ok,N/A +MAR08380,MAM02040c + MAM02523c --> MAM01143c + MAM01252c,MAM01143c;MAM02523c,ok,ok,ok,N/A +MAR07186,MAM02040r + MAM02523r --> MAM01143r + MAM01252r,MAM01143r;MAM02523r,ok,ok,ok,N/A +MAR08381,MAM01143c + MAM02678c --> MAM01597c + MAM01964c,MAM01143c;MAM01964c,ok,ok,ok,N/A +MAR07187,MAM01143r + MAM02678r --> MAM01597r + MAM01964r,MAM01143r;MAM01964r,ok,ok,ok,N/A +MAR08383,MAM01734r + MAM01964r --> MAM01733r + MAM02039r + MAM02483r,MAM01964r;MAM02483r,ok,ok,ok,N/A +MAR08384,MAM01734r + MAM02483r --> MAM01733r + MAM02039r + MAM02431r,MAM02431r;MAM02483r,ok,ok,ok,N/A +MAR08385,MAM01734r + MAM02431r --> MAM01733r + MAM02039r + MAM02433r,MAM02431r;MAM02433r,ok,ok,ok,N/A +MAR08387,MAM01734r + MAM01783r --> MAM01733r + MAM02039r + MAM02463r,MAM01783r;MAM02463r,ok,ok,ok,N/A +MAR08388,MAM01734r + MAM02463r --> MAM01733r + MAM02039r + MAM02430r,MAM02430r;MAM02463r,ok,ok,ok,N/A +MAR08389,MAM01734r + MAM02430r --> MAM01733r + MAM02039r + MAM02432r,MAM02430r;MAM02432r,ok,ok,ok,N/A +MAR08390,MAM01734r + MAM01779r --> MAM01733r + MAM02039r + MAM02461r,MAM01779r;MAM02461r,ok,ok,ok,N/A +MAR08391,MAM02483r + MAM02685r --> MAM00236r + MAM01783r,MAM00236r;MAM01783r;MAM02483r,ok,ok,ok,N/A +MAR08392,MAM02431r + MAM02685r --> MAM00236r + MAM02463r,MAM00236r;MAM02431r;MAM02463r,ok,ok,ok,N/A +MAR08393,MAM02433r + MAM02685r --> MAM00236r + MAM01781r,MAM00236r;MAM01781r;MAM02433r,ok,ok,ok,N/A +MAR08394,MAM02433r + MAM02685r --> MAM00236r + MAM02430r,MAM00236r;MAM02430r;MAM02433r,ok,ok,ok,N/A +MAR08395,MAM01781r + MAM02685r --> MAM00236r + MAM01782r,MAM00236r;MAM01781r;MAM01782r,ok,ok,ok,N/A +MAR08396,MAM02430r + MAM02685r --> MAM00236r + MAM01779r,MAM00236r;MAM01779r;MAM02430r,ok,ok,ok,N/A +MAR08397,MAM01781r + MAM02685r --> MAM00236r + MAM01779r,MAM00236r;MAM01779r;MAM01781r,ok,ok,ok,N/A +MAR08398,MAM01779r + MAM02685r --> MAM00236r + MAM02020r,MAM00236r;MAM01779r;MAM02020r,ok,ok,ok,N/A +MAR08399,MAM01782r + MAM02685r --> MAM00236r + MAM02020r,MAM00236r;MAM01782r;MAM02020r,ok,ok,ok,N/A +MAR08401,MAM02432r + MAM02685r --> MAM00236r + MAM02461r,MAM00236r;MAM02432r;MAM02461r,ok,ok,ok,N/A +MAR08402,MAM01779r + MAM02001r --> MAM01780r + MAM02022r,MAM01779r;MAM01780r;MAM02001r;MAM02022r,ok,ok,ok,N/A +MAR08403,MAM01780r + MAM02040r --> MAM01665r + MAM02039r + MAM02674r,MAM01665r;MAM01780r,ok,ok,ok,N/A +MAR08404,MAM02001r + MAM02020r --> MAM02021r + MAM02022r,MAM02001r;MAM02020r;MAM02021r;MAM02022r,ok,ok,ok,N/A +MAR08405,MAM02021r + MAM02040r --> MAM01687r + MAM02039r + MAM02674r,MAM01687r;MAM02021r,ok,ok,ok,N/A +MAR08406,MAM02001r + MAM02433r --> MAM02022r + MAM02434r,MAM02001r;MAM02022r;MAM02433r;MAM02434r,ok,ok,ok,N/A +MAR08407,MAM02001r + MAM02461r --> MAM02022r + MAM02462r,MAM02001r;MAM02022r;MAM02461r;MAM02462r,ok,ok,ok,N/A MAR01979,MAM02552c + MAM02763c --> MAM02039c + MAM02553c + MAM02760c,ok,ok,ok,ok,N/A MAR01980,MAM02760c --> MAM02769c,ok,ok,ok,ok,N/A MAR01981,MAM02039c + MAM02555c + MAM02630c + MAM02769c --> MAM00409c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A @@ -3985,9 +3985,9 @@ MAR07486,2 MAM02040l + MAM02300l --> 2 MAM01910l + MAM02301l,ok,ok,ok,ok,N/A MAR07487,MAM02040l + MAM02301l --> MAM02039l + MAM02302l + MAM02946l,ok,ok,ok,ok,N/A MAR07488,3 MAM02040l + MAM02301l --> MAM02039l + MAM02283l + 2 MAM02527l + MAM02946l,ok,ok,ok,ok,N/A MAR07489,2 MAM02040l + MAM02302l --> MAM02283l + 2 MAM02527l,ok,ok,ok,ok,N/A -MAR08643,MAM01601c + MAM02040c --> MAM01380c + MAM01767c + MAM02039c,ok,ok,ok,ok,N/A -MAR08645,MAM01601r + MAM02040r --> MAM01380r + MAM01767r + MAM02039r,ok,ok,ok,ok,N/A -MAR08648,MAM01767r + MAM02040r --> MAM01766r + MAM02039r + MAM02470r,MAM01766r;MAM02470r,ok,ok,ok,N/A +MAR08643,MAM01601c + MAM02040c --> MAM01380c + MAM01767c + MAM02039c,MAM01601c;MAM01767c,ok,ok,ok,N/A +MAR08645,MAM01601r + MAM02040r --> MAM01380r + MAM01767r + MAM02039r,MAM01380r;MAM01601r;MAM01767r,ok,ok,ok,N/A +MAR08648,MAM01767r + MAM02040r --> MAM01766r + MAM02039r + MAM02470r,MAM01766r;MAM01767r;MAM02470r,ok,ok,ok,N/A MAR01581,MAM01450r + MAM02039r + MAM02555r + MAM02630r --> MAM01183r + MAM02040r + MAM02554r,ok,ok,ok,ok,N/A MAR01584,MAM01183r + MAM02552r --> MAM01182r + MAM02039r + MAM02553r,ok,ok,ok,ok,N/A MAR01585,MAM01183r + MAM02554r --> MAM01182r + MAM02039r + MAM02555r,ok,ok,ok,ok,N/A @@ -4624,7 +4624,7 @@ MAR06702,MAM00993c + MAM02039c + MAM02555c + MAM02630c --> MAM01031c + 2 MAM0204 MAR06703,MAM00993r + MAM02039r + MAM02555r + MAM02630r --> MAM01031r + 2 MAM02040r + MAM02554r,ok,ok,ok,ok,N/A MAR06704,MAM00993c + MAM03109c --> MAM02039c + MAM02824c + MAM03106c,MAM02824c,ok,ok,ok,N/A MAR06705,MAM00993r + MAM03109r --> MAM02039r + MAM02824r + MAM03106r,MAM02824r,ok,ok,ok,N/A -MAR08697,MAM01385c + MAM02630c --> 2 MAM02832c,ok,ok,ok,ok,N/A +MAR08697,MAM01385c + MAM02630c --> 2 MAM02832c,MAM01385c,ok,ok,ok,N/A MAR08698,2 MAM02039c + MAM02555c + MAM02833c <=> MAM02040c + MAM02554c + MAM02832c,ok,ok,ok,ok,N/A MAR08699,MAM00349c + MAM02040c + MAM02554c <=> MAM00350c + 2 MAM02039c + MAM02555c,ok,ok,ok,ok,N/A MAR08700,MAM02039c + MAM02555c + MAM02630c + MAM02833c --> MAM01006c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A @@ -4705,7 +4705,7 @@ MAR02142,MAM01416c + MAM02039c + MAM02555c + MAM02630c --> MAM00612c + 2 MAM0204 MAR02143,MAM01416m + MAM02039m + MAM02555m + MAM02630m --> MAM00612m + 2 MAM02040m + MAM02554m,ok,ok,ok,ok,N/A MAR02144,MAM00612c + MAM02039c + MAM02555c + MAM02630c --> MAM00611c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A MAR02145,MAM00612m + MAM02039m + MAM02555m + MAM02630m --> MAM00611m + MAM02040m + MAM02554m,ok,ok,ok,ok,N/A -MAR07996,MAM02039m + MAM02555m + MAM02630m + MAM03141m --> MAM00620m + MAM02040m + MAM02554m,ok,ok,ok,ok,N/A +MAR07996,MAM02039m + MAM02555m + MAM02630m + MAM03141m --> MAM00620m + MAM02040m + MAM02554m,MAM03141m,ok,ok,ok,N/A MAR07999,MAM00620m + MAM02039m + MAM02555m + MAM02630m --> MAM00613m + MAM02040m + MAM02554m,ok,ok,ok,ok,N/A MAR08003,MAM00613m + MAM02039m + MAM02555m + MAM02630m --> MAM00518m + MAM02040m + MAM02554m,MAM00518m,ok,ok,ok,N/A MAR08004,MAM00620m + MAM02039m + MAM02555m + MAM02630m --> MAM00519m + MAM02040m + MAM02554m,ok,ok,ok,ok,N/A @@ -4876,21 +4876,21 @@ MAR07103,MAM00242c + MAM02026c --> MAM01978c + 2 MAM02039c + 2 MAM02143c,ok,ok,o MAR07104,MAM01978c + MAM02040c --> MAM02855c,ok,ok,ok,ok,N/A MAR07106,3 MAM02039c + MAM02861c --> MAM02855c,ok,ok,ok,ok,N/A MAR07688,MAM02682c + MAM02754c --> MAM01021c + MAM02039c + MAM02681c,ok,ok,ok,ok,N/A -MAR08032,MAM01647c + MAM02039c + MAM02555c + MAM02630c --> MAM00998c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A +MAR08032,MAM01647c + MAM02039c + MAM02555c + MAM02630c --> MAM00998c + MAM02040c + MAM02554c,MAM00998c;MAM01647c,ok,ok,ok,N/A MAR08034,MAM02039c + MAM02555c + MAM02630c + MAM02754c --> MAM01019c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A MAR08036,MAM02039c + MAM02344c + MAM02555c + MAM02630c --> MAM00325c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A MAR08037,MAM02039c + MAM02494c + MAM02555c + MAM02630c --> MAM00371c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A MAR08038,MAM02039c + MAM02555c + MAM02630c + MAM02674c --> MAM00403c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A -MAR08040,MAM01617c + MAM02039c + MAM02555c + MAM02630c --> MAM02040c + MAM02554c + MAM03113c,ok,ok,ok,ok,N/A -MAR08043,MAM01344c + MAM02039c + MAM02555c + 0.5 MAM02630c --> MAM01768c + MAM02470c + MAM02554c,ok,ok,ok,ok,N/A -MAR08046,MAM02039c + MAM02555c + MAM02630c + MAM02653c --> MAM01109c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A -MAR08049,MAM02039c + MAM02555c + MAM02630c + MAM02673c --> MAM01163c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A -MAR08052,MAM02039c + MAM02555c + MAM02630c + MAM03001c --> MAM01007c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A -MAR08055,MAM02039c + MAM02555c + MAM02587c + MAM02630c --> MAM02040c + MAM02153c + MAM02554c,ok,ok,ok,ok,N/A -MAR08059,MAM01765r + MAM02039r + MAM02555r + MAM02630r --> MAM02040r + MAM02150r + MAM02554r,ok,ok,ok,ok,N/A -MAR08596,MAM02039c + MAM02386c + MAM02555c + MAM02630c --> MAM00001c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A -MAR08598,MAM02039c + MAM02386c + MAM02555c + MAM02630c --> MAM02040c + MAM02554c + MAM02712c,ok,ok,ok,ok,N/A -MAR08601,MAM00002c + MAM02039c + MAM02555c + MAM02630c --> MAM01326c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A +MAR08040,MAM01617c + MAM02039c + MAM02555c + MAM02630c --> MAM02040c + MAM02554c + MAM03113c,MAM01617c;MAM03113c,ok,ok,ok,N/A +MAR08043,MAM01344c + MAM02039c + MAM02555c + 0.5 MAM02630c --> MAM01768c + MAM02470c + MAM02554c,MAM01344c;MAM01768c,ok,ok,ok,N/A +MAR08046,MAM02039c + MAM02555c + MAM02630c + MAM02653c --> MAM01109c + MAM02040c + MAM02554c,MAM01109c;MAM02653c,ok,ok,ok,N/A +MAR08049,MAM02039c + MAM02555c + MAM02630c + MAM02673c --> MAM01163c + MAM02040c + MAM02554c,MAM01163c;MAM02673c,ok,ok,ok,N/A +MAR08052,MAM02039c + MAM02555c + MAM02630c + MAM03001c --> MAM01007c + MAM02040c + MAM02554c,MAM01007c;MAM03001c,ok,ok,ok,N/A +MAR08055,MAM02039c + MAM02555c + MAM02587c + MAM02630c --> MAM02040c + MAM02153c + MAM02554c,MAM02153c;MAM02587c,ok,ok,ok,N/A +MAR08059,MAM01765r + MAM02039r + MAM02555r + MAM02630r --> MAM02040r + MAM02150r + MAM02554r,MAM01765r;MAM02150r,ok,ok,ok,N/A +MAR08596,MAM02039c + MAM02386c + MAM02555c + MAM02630c --> MAM00001c + MAM02040c + MAM02554c,MAM00001c;MAM02386c,ok,ok,ok,N/A +MAR08598,MAM02039c + MAM02386c + MAM02555c + MAM02630c --> MAM02040c + MAM02554c + MAM02712c,MAM02386c;MAM02712c,ok,ok,ok,N/A +MAR08601,MAM00002c + MAM02039c + MAM02555c + MAM02630c --> MAM01326c + MAM02040c + MAM02554c,MAM00002c;MAM01326c,ok,ok,ok,N/A MAR06535,MAM02040c + MAM02156c <=> MAM01442c + MAM02039c + MAM02041c,MAM02156c,ok,ok,ok,N/A MAR06536,MAM02039c + MAM02156c + MAM02588c <=> MAM02040c + MAM02591c,MAM02156c;MAM02591c,ok,ok,ok,N/A MAR09569,MAM01020e + MAM02040e --> MAM02751e + MAM02754e,ok,ok,ok,ok,N/A @@ -4992,8 +4992,8 @@ MAR09550,2 MAM00188c + MAM02555c + 2 MAM02877c <=> 2 MAM00189c + MAM02039c + MAM MAR09551,MAM01838c + MAM02040c --> MAM01833c + MAM02039c + MAM02472c,MAM01838c;MAM02472c,ok,ok,ok,N/A MAR09552,MAM01710c + MAM02040c --> MAM02039c + MAM02493c + MAM02751c,MAM01710c;MAM02493c,ok,ok,ok,N/A MAR09553,MAM01306c + MAM02630c + MAM02768c --> MAM01596c + MAM02767c + MAM02943c,MAM02767c;MAM02768c,ok,ok,ok,N/A -MAR09801,MAM02034c + MAM02381c <=> MAM01948c + MAM03167c,only when going backwards,ok,ok,ok,N/A -MAR09807,MAM02040c + MAM03167c --> MAM00631c + MAM02039c + MAM02578c + MAM02751c,ok,ok,ok,ok,N/A +MAR09801,MAM02034c + MAM02381c <=> MAM01948c + MAM03167c,MAM02381c;MAM03167c,ok,ok,ok,N/A +MAR09807,MAM02040c + MAM03167c --> MAM00631c + MAM02039c + MAM02578c + MAM02751c,MAM03167c,ok,ok,ok,N/A MAR09554,MAM00683c + 2 MAM02040c --> MAM00774c + 2 MAM02039c + 2 MAM10005c,MAM00683c;MAM00774c,ok,ok,ok,N/A MAR09555,MAM01581c + MAM02040c --> MAM01578c + MAM01965c + MAM02039c,MAM01578c;MAM01581c,ok,ok,ok,N/A MAR09556,MAM02040e + MAM02333e --> MAM02332e + MAM02751e,ok,ok,ok,ok,N/A @@ -5203,7 +5203,7 @@ MAR00432,MAM00021e --> MAM00021c,ok,ok,ok,ok,N/A MAR00435,MAM00021c + MAM01371c + MAM02040c --> MAM00021e + MAM01285c + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A MAR00436,MAM00265e --> MAM00265c,ok,ok,ok,ok,N/A MAR00439,MAM00265c + MAM01371c + MAM02040c --> MAM00265e + MAM01285c + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A -MAR00440,MAM02746e <=> MAM02746c,only when going backwards,ok,ok,ok,N/A +MAR00440,MAM02746e <=> MAM02746c,MAM02746c;MAM02746e,ok,ok,ok,N/A MAR00444,MAM01983c <=> MAM01983e,ok,ok,ok,ok,N/A MAR00469,MAM01371c + MAM02040c + MAM02685c --> MAM01285c + MAM02039c + MAM02685e + MAM02751c,ok,ok,ok,MAR01594,N/A MAR00470,MAM01371c + MAM01395c + MAM02040c --> MAM01285c + MAM01395e + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A @@ -5293,7 +5293,7 @@ MAR04994,MAM02923c <=> MAM02923e,ok,ok,ok,ok,N/A MAR04995,MAM01588e + MAM02039e + MAM02658c --> MAM01588c + MAM02039c + MAM02658e,ok,ok,ok,ok,N/A MAR04996,MAM01962e --> MAM01962c,ok,ok,ok,ok,N/A MAR04999,MAM02124c <=> MAM02124e,ok,ok,ok,ok,N/A -MAR05000,MAM01796c <=> MAM01796e,only when going forwards,ok,ok,ok,N/A +MAR05000,MAM01796c <=> MAM01796e,MAM01796c;MAM01796e,ok,ok,ok,N/A MAR05002,MAM02841c <=> MAM02841e,ok,ok,ok,ok,N/A MAR05003,MAM01630c <=> MAM01630e,ok,ok,ok,ok,N/A MAR05005,MAM01396e + MAM02519e --> MAM01396c + MAM02519c,ok,ok,ok,ok,N/A @@ -5353,7 +5353,7 @@ MAR05237,MAM02352e --> MAM02352l,ok,ok,ok,ok,N/A MAR05240,MAM02353r --> MAM02353e,ok,ok,ok,ok,N/A MAR05241,MAM03146e --> MAM03146l,ok,ok,ok,ok,N/A MAR05246,MAM01569e --> MAM01569l,ok,ok,ok,ok,N/A -MAR05296,MAM02470c <=> MAM02470e,ok,ok,ok,ok,N/A +MAR05296,MAM02470c <=> MAM02470e,only when going forwards,ok,ok,ok,N/A MAR05303,MAM01371c <=> MAM01371e,ok,ok,ok,ok,N/A MAR05305,MAM01307e + MAM02519e --> MAM01307c + MAM02519c,ok,ok,ok,ok,N/A MAR05307,MAM01307e + MAM02039c + 2 MAM02519e --> MAM01307c + MAM02039e + 2 MAM02519c,ok,ok,ok,MAR09605,N/A @@ -6354,30 +6354,30 @@ MAR07979,MAM02968c <=> MAM02968e,only when going backwards,ok,ok,ok,N/A MAR07982,MAM01371c + MAM01799c + MAM02040c --> MAM01285c + MAM01799e + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A MAR07986,MAM00402c + MAM01371c + MAM02040c --> MAM00402e + MAM01285c + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A MAR07990,MAM01070c + MAM01371c + MAM02040c --> MAM01070e + MAM01285c + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A -MAR07994,MAM03141c <=> MAM03141e,only when going forwards,ok,ok,ok,N/A -MAR07997,MAM00620c <=> MAM00620e,ok,ok,ok,ok,N/A +MAR07994,MAM03141c <=> MAM03141e,MAM03141c;MAM03141e,ok,ok,ok,N/A +MAR07997,MAM00620c <=> MAM00620e,only when going forwards,ok,ok,ok,N/A MAR08002,MAM00613c --> MAM00613e,ok,ok,ok,ok,N/A MAR08007,MAM00035c --> MAM00035e,ok,ok,ok,ok,N/A MAR08010,MAM01415c <=> MAM01415e,ok,ok,ok,ok,N/A MAR08015,MAM03142c --> MAM03142e,ok,ok,ok,ok,N/A MAR08023,MAM00204c <=> MAM00204e,ok,ok,ok,ok,N/A -MAR08031,MAM01647c <=> MAM01647e,only when going forwards,ok,ok,ok,N/A -MAR08033,MAM00998c <=> MAM00998e,only when going backwards,ok,ok,ok,N/A +MAR08031,MAM01647c <=> MAM01647e,MAM01647c;MAM01647e,ok,ok,ok,N/A +MAR08033,MAM00998c <=> MAM00998e,MAM00998c;MAM00998e,ok,ok,ok,N/A MAR08035,MAM01019c <=> MAM01019e,only when going backwards,ok,ok,ok,N/A -MAR08039,MAM01617c <=> MAM01617e,only when going forwards,ok,ok,ok,N/A -MAR08041,MAM03113c <=> MAM03113e,only when going backwards,ok,ok,ok,N/A -MAR08042,MAM01344c <=> MAM01344e,only when going forwards,ok,ok,ok,N/A -MAR08044,MAM01768c <=> MAM01768e,only when going backwards,ok,ok,ok,N/A -MAR08045,MAM02653c <=> MAM02653e,only when going forwards,ok,ok,ok,N/A -MAR08047,MAM01109c <=> MAM01109e,only when going backwards,ok,ok,ok,N/A -MAR08048,MAM02673c <=> MAM02673e,only when going forwards,ok,ok,ok,N/A -MAR08050,MAM01163c <=> MAM01163e,only when going backwards,ok,ok,ok,N/A -MAR08051,MAM03001c <=> MAM03001e,only when going forwards,ok,ok,ok,N/A -MAR08053,MAM01007c <=> MAM01007e,only when going backwards,ok,ok,ok,N/A -MAR08054,MAM02587c <=> MAM02587e,only when going forwards,ok,ok,ok,N/A -MAR08056,MAM02153c <=> MAM02153e,only when going backwards,ok,ok,ok,N/A -MAR08057,MAM01765c <=> MAM01765e,only when going forwards,ok,ok,ok,N/A -MAR08061,MAM02150c <=> MAM02150e,only when going backwards,ok,ok,ok,N/A +MAR08039,MAM01617c <=> MAM01617e,MAM01617c;MAM01617e,ok,ok,ok,N/A +MAR08041,MAM03113c <=> MAM03113e,MAM03113c;MAM03113e,ok,ok,ok,N/A +MAR08042,MAM01344c <=> MAM01344e,MAM01344c;MAM01344e,ok,ok,ok,N/A +MAR08044,MAM01768c <=> MAM01768e,MAM01768c;MAM01768e,ok,ok,ok,N/A +MAR08045,MAM02653c <=> MAM02653e,MAM02653c;MAM02653e,ok,ok,ok,N/A +MAR08047,MAM01109c <=> MAM01109e,MAM01109c;MAM01109e,ok,ok,ok,N/A +MAR08048,MAM02673c <=> MAM02673e,MAM02673c;MAM02673e,ok,ok,ok,N/A +MAR08050,MAM01163c <=> MAM01163e,MAM01163c;MAM01163e,ok,ok,ok,N/A +MAR08051,MAM03001c <=> MAM03001e,MAM03001c;MAM03001e,ok,ok,ok,N/A +MAR08053,MAM01007c <=> MAM01007e,MAM01007c;MAM01007e,ok,ok,ok,N/A +MAR08054,MAM02587c <=> MAM02587e,MAM02587c;MAM02587e,ok,ok,ok,N/A +MAR08056,MAM02153c <=> MAM02153e,MAM02153c;MAM02153e,ok,ok,ok,N/A +MAR08057,MAM01765c <=> MAM01765e,MAM01765c;MAM01765e,ok,ok,ok,N/A +MAR08061,MAM02150c <=> MAM02150e,MAM02150c;MAM02150e,ok,ok,ok,N/A MAR08073,MAM01672c <=> MAM01672e,ok,ok,ok,ok,N/A MAR08075,MAM00648e + MAM02039e --> MAM00648c + MAM02039c,ok,ok,ok,ok,N/A MAR08076,2 MAM02046c + MAM02519c --> 2 MAM02046e + MAM02519e,ok,ok,ok,MAR05432;MAR05448;MAR08077,N/A @@ -6419,11 +6419,11 @@ MAR08324,MAM02331c <=> MAM02331e,only when going backwards,ok,ok,ok,N/A MAR08329,MAM00744c <=> MAM00744e,only when going backwards,ok,ok,ok,N/A MAR08336,MAM02164c <=> MAM02164e,only when going backwards,ok,ok,ok,N/A MAR08339,MAM03138c <=> MAM03138e,only when going backwards,ok,ok,ok,N/A -MAR08340,MAM02337c <=> MAM02337e,only when going forwards,ok,ok,ok,N/A +MAR08340,MAM02337c <=> MAM02337e,MAM02337c;MAM02337e,ok,ok,ok,N/A MAR08343,MAM02338c --> MAM02338e,ok,ok,ok,ok,N/A MAR08354,MAM00970e + MAM02039e --> MAM00970c + MAM02039c,ok,ok,ok,ok,N/A MAR08364,MAM01256e + MAM02039e --> MAM01256c + MAM02039c,ok,ok,ok,ok,N/A -MAR08374,MAM01438c <=> MAM01438e,only when going forwards,ok,ok,ok,N/A +MAR08374,MAM01438c <=> MAM01438e,MAM01438c;MAM01438e,ok,ok,ok,N/A MAR08408,MAM02041c <=> MAM02041e,ok,ok,ok,ok,N/A MAR08420,MAM00577c <=> MAM00577e,ok,ok,ok,ok,N/A MAR08429,MAM01619e + 2 MAM02519e --> MAM01619c + 2 MAM02519c,ok,ok,ok,ok,N/A @@ -6431,14 +6431,14 @@ MAR08515,MAM02403e + MAM02519e --> MAM02403c + MAM02519c,ok,ok,ok,ok,N/A MAR08520,MAM00516c <=> MAM00516e,ok,ok,ok,ok,N/A MAR08536,MAM03100c --> MAM03100e,ok,ok,ok,ok,N/A MAR08551,MAM02046c + MAM02366e --> MAM02046e + MAM02366c,ok,ok,ok,ok,N/A -MAR08567,MAM02445c <=> MAM02445e,only when going forwards,ok,ok,ok,N/A +MAR08567,MAM02445c <=> MAM02445e,MAM02445c;MAM02445e,ok,ok,ok,N/A MAR08586,MAM02450c <=> MAM02450e,ok,ok,ok,ok,N/A MAR08593,MAM01338c <=> MAM01338e,ok,ok,ok,ok,N/A -MAR08595,MAM02386c <=> MAM02386e,only when going forwards,ok,ok,ok,N/A -MAR08597,MAM00001c <=> MAM00001e,only when going backwards,ok,ok,ok,N/A -MAR08599,MAM02712c <=> MAM02712e,only when going backwards,ok,ok,ok,N/A -MAR08600,MAM00002c <=> MAM00002e,only when going forwards,ok,ok,ok,N/A -MAR08602,MAM01326c <=> MAM01326e,only when going backwards,ok,ok,ok,N/A +MAR08595,MAM02386c <=> MAM02386e,MAM02386c;MAM02386e,ok,ok,ok,N/A +MAR08597,MAM00001c <=> MAM00001e,MAM00001c;MAM00001e,ok,ok,ok,N/A +MAR08599,MAM02712c <=> MAM02712e,MAM02712c;MAM02712e,ok,ok,ok,N/A +MAR08600,MAM00002c <=> MAM00002e,MAM00002c;MAM00002e,ok,ok,ok,N/A +MAR08602,MAM01326c <=> MAM01326e,MAM01326c;MAM01326e,ok,ok,ok,N/A MAR08612,MAM01361e --> MAM01361c,ok,ok,ok,ok,N/A MAR08618,MAM01368c <=> MAM01368e,ok,ok,ok,ok,N/A MAR08629,MAM01365e + MAM02519e --> MAM01365c + MAM02519c,ok,ok,ok,ok,N/A @@ -6446,7 +6446,7 @@ MAR08631,MAM01397e + MAM02046c --> MAM01397c + MAM02046e,ok,ok,ok,ok,N/A MAR08632,MAM01398e + MAM02046c --> MAM01398c + MAM02046e,ok,ok,ok,ok,N/A MAR08633,MAM01371c + MAM01398c + MAM02040c --> MAM01285c + MAM01398e + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A MAR08635,MAM01396e + MAM02046c --> MAM01396c + MAM02046e,ok,ok,ok,ok,N/A -MAR08636,MAM01632c <=> MAM01632e,only when going forwards,ok,ok,ok,N/A +MAR08636,MAM01632c <=> MAM01632e,MAM01632c;MAM01632e,ok,ok,ok,N/A MAR08656,MAM01418c --> MAM01418e,MAM01418c;MAM01418e,ok,ok,ok,N/A MAR08658,MAM01371c + MAM01445c + MAM02040c --> MAM01285c + MAM01445e + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A MAR08659,MAM01445e + MAM02046c --> MAM01445c + MAM02046e,ok,ok,ok,ok,N/A @@ -6459,7 +6459,7 @@ MAR08678,MAM01615c <=> MAM01615e,ok,ok,ok,ok,N/A MAR08679,MAM01614c <=> MAM01614e,ok,ok,ok,ok,N/A MAR08686,MAM00816c --> MAM00816e,ok,ok,ok,ok,N/A MAR08687,MAM01629e + MAM02896c --> MAM01629c + MAM02896e,ok,ok,ok,ok,N/A -MAR08696,MAM01385c <=> MAM01385e,only when going forwards,ok,ok,ok,N/A +MAR08696,MAM01385c <=> MAM01385e,MAM01385c;MAM01385e,ok,ok,ok,N/A MAR08714,MAM02836c --> MAM02836e,ok,ok,ok,ok,N/A MAR08718,MAM00353c --> MAM00353e,ok,ok,ok,ok,N/A MAR08720,MAM10005c --> MAM10005e,ok,ok,ok,ok,N/A @@ -6536,15 +6536,15 @@ MAR08944,MAM01291e + MAM02519e --> MAM01291c + MAM02519c,ok,ok,ok,ok,N/A MAR08945,MAM01689e + MAM02519e --> MAM01689c + MAM02519c,ok,ok,ok,ok,N/A MAR08946,MAM02385e + MAM02519e --> MAM02385c + MAM02519c,ok,ok,ok,ok,N/A MAR08947,MAM02519e + MAM02564e --> MAM02519c + MAM02564c,ok,ok,ok,ok,N/A -MAR09173,MAM03154c <=> MAM03154e,only when going forwards,ok,ok,ok,N/A +MAR09173,MAM03154c <=> MAM03154e,MAM03154c;MAM03154e,ok,ok,ok,N/A MAR09175,MAM02191c <=> MAM02191e,ok,ok,ok,ok,N/A MAR09176,MAM01788c <=> MAM01788e,ok,ok,ok,ok,N/A MAR09178,MAM01800c <=> MAM01800e,ok,ok,ok,ok,N/A MAR09180,MAM01740c <=> MAM01740e,ok,ok,ok,ok,N/A -MAR09182,MAM01640c <=> MAM01640e,only when going forwards,ok,ok,ok,N/A -MAR09183,MAM01286c <=> MAM01286e,only when going forwards,ok,ok,ok,N/A -MAR09184,MAM01287c <=> MAM01287e,only when going forwards,ok,ok,ok,N/A -MAR09185,MAM01743c <=> MAM01743e,only when going forwards,ok,ok,ok,N/A +MAR09182,MAM01640c <=> MAM01640e,MAM01640c;MAM01640e,ok,ok,ok,N/A +MAR09183,MAM01286c <=> MAM01286e,MAM01286c;MAM01286e,ok,ok,ok,N/A +MAR09184,MAM01287c <=> MAM01287e,MAM01287c;MAM01287e,ok,ok,ok,N/A +MAR09185,MAM01743c <=> MAM01743e,MAM01743c;MAM01743e,ok,ok,ok,N/A MAR09187,MAM01966c <=> MAM01966e,only when going backwards,ok,ok,ok,N/A MAR09188,MAM02155c <=> MAM02155e,ok,ok,ok,ok,N/A MAR09189,MAM01989c <=> MAM01989e,ok,ok,ok,ok,N/A @@ -6591,7 +6591,7 @@ MAR09621,MAM02519e + MAM02952e --> MAM02519c + MAM02952c,ok,ok,ok,ok,N/A MAR09622,MAM02403c + MAM03120e --> MAM02403e + MAM03120c,ok,ok,ok,ok,N/A MAR09623,MAM01306c + MAM01659e --> MAM01306e + MAM01659c,ok,ok,ok,ok,N/A MAR09624,MAM01306c + MAM01789e --> MAM01306e + MAM01789c,ok,ok,ok,ok,N/A -MAR09635,MAM02022c <=> MAM02022e,only when going backwards,ok,ok,ok,N/A +MAR09635,MAM02022c <=> MAM02022e,MAM02022c;MAM02022e,ok,ok,ok,N/A MAR09636,MAM02384c --> MAM02384e,ok,ok,ok,ok,N/A MAR09637,MAM01098c <=> MAM01098e,only when going backwards,ok,ok,ok,N/A MAR09638,MAM00969c <=> MAM00969e,ok,ok,ok,ok,N/A @@ -6609,20 +6609,20 @@ MAR09649,MAM01603c <=> MAM01603e,ok,ok,ok,ok,N/A MAR09650,MAM01604c <=> MAM01604e,ok,ok,ok,ok,N/A MAR09651,MAM01887c <=> MAM01887e,only when going backwards,ok,ok,ok,N/A MAR09652,MAM02137c --> MAM02137e,ok,ok,ok,ok,N/A -MAR09653,MAM01687c <=> MAM01687e,only when going backwards,ok,ok,ok,N/A -MAR09654,MAM01665c <=> MAM01665e,only when going backwards,ok,ok,ok,N/A +MAR09653,MAM01687c <=> MAM01687e,MAM01687c;MAM01687e,ok,ok,ok,N/A +MAR09654,MAM01665c <=> MAM01665e,MAM01665c;MAM01665e,ok,ok,ok,N/A MAR09655,MAM01955c <=> MAM01955e,only when going backwards,ok,ok,ok,N/A MAR09656,MAM01006c <=> MAM01006e,only when going backwards,ok,ok,ok,N/A MAR09657,MAM00771c <=> MAM00771e,only when going backwards,ok,ok,ok,N/A -MAR09658,MAM02434c <=> MAM02434e,only when going backwards,ok,ok,ok,N/A +MAR09658,MAM02434c <=> MAM02434e,MAM02434c;MAM02434e,ok,ok,ok,N/A MAR09659,MAM02458c <=> MAM02458e,only when going backwards,ok,ok,ok,N/A MAR09660,MAM01610c <=> MAM01610e,ok,ok,ok,ok,N/A MAR09661,MAM01612c <=> MAM01612e,ok,ok,ok,ok,N/A MAR09662,MAM01613c <=> MAM01613e,ok,ok,ok,ok,N/A -MAR09663,MAM02462c <=> MAM02462e,only when going backwards,ok,ok,ok,N/A +MAR09663,MAM02462c <=> MAM02462e,MAM02462c;MAM02462e,ok,ok,ok,N/A MAR09720,MAM01730c --> MAM01730e,ok,ok,ok,ok,N/A MAR09728,MAM03161c <=> MAM03161e,ok,ok,ok,ok,N/A -MAR09731,MAM02001c <=> MAM02001e,only when going forwards,ok,ok,ok,N/A +MAR09731,MAM02001c <=> MAM02001e,MAM02001c;MAM02001e,ok,ok,ok,N/A MAR09737,MAM01370c --> MAM01370e,ok,ok,ok,ok,N/A MAR08071,MAM00179c --> MAM00179e,ok,ok,ok,ok,N/A MAR04312,MAM01682c <=> MAM01682e,ok,ok,ok,ok,N/A @@ -6898,8 +6898,8 @@ MAR07899,MAM01714c <=> MAM01714m,MAM01714m,ok,ok,ok,N/A MAR07914,MAM00267m --> MAM00267c,ok,ok,ok,ok,N/A MAR07917,MAM00268m --> MAM00268c,ok,ok,ok,ok,N/A MAR07923,MAM00269m --> MAM00269c,ok,ok,ok,ok,N/A -MAR07995,MAM03141c <=> MAM03141m,only when going backwards,ok,ok,ok,N/A -MAR07998,MAM00620c <=> MAM00620m,ok,ok,ok,ok,N/A +MAR07995,MAM03141c <=> MAM03141m,MAM03141c;MAM03141m,ok,ok,ok,N/A +MAR07998,MAM00620c <=> MAM00620m,only when going backwards,ok,ok,ok,N/A MAR08000,MAM00035m --> MAM00035c,ok,ok,ok,ok,N/A MAR08001,MAM00613m --> MAM00613c,ok,ok,ok,ok,N/A MAR08009,MAM01415c <=> MAM01415m,ok,ok,ok,ok,N/A @@ -7017,14 +7017,14 @@ MAR07779,MAM02555c --> MAM02555x,ok,ok,ok,ok,N/A MAR07797,MAM01306c <=> MAM01306x,ok,ok,ok,ok,N/A MAR08016,MAM02426c --> MAM02426x,ok,ok,ok,ok,N/A MAR08020,MAM00556c <=> MAM00556x,only when going forwards,ok,ok,ok,N/A -MAR08359,MAM01249c <=> MAM01249x,only when going forwards,ok,ok,ok,N/A +MAR08359,MAM01249c <=> MAM01249x,MAM01249x,ok,ok,ok,N/A MAR08414,MAM02631c <=> MAM02631x,only when going backwards,ok,ok,ok,N/A MAR08754,MAM02159c --> MAM02159x,ok,ok,ok,ok,N/A -MAR08756,MAM01796c <=> MAM01796x,only when going backwards,ok,ok,ok,N/A +MAR08756,MAM01796c <=> MAM01796x,MAM01796c;MAM01796x,ok,ok,ok,N/A MAR08860,MAM03120x --> MAM03120c,ok,ok,ok,ok,N/A MAR08926,MAM02578c <=> MAM02578x,only when going forwards,ok,ok,ok,N/A MAR09179,MAM01740c <=> MAM01740x,ok,ok,ok,ok,N/A -MAR09181,MAM01640c <=> MAM01640x,only when going backwards,ok,ok,ok,N/A +MAR09181,MAM01640c <=> MAM01640x,MAM01640c;MAM01640x,ok,ok,ok,N/A MAR09678,MAM02674x --> MAM02674c,ok,ok,ok,ok,N/A MAR09679,MAM01252x <=> MAM01252c,only when going backwards,ok,ok,ok,N/A MAR09680,MAM02633x <=> MAM02633c,ok,ok,ok,ok,N/A @@ -7116,7 +7116,7 @@ MAR02040,MAM01790c <=> MAM01790l,MAM01790l,ok,ok,ok,N/A MAR02087,MAM00986c <=> MAM00986l,ok,ok,ok,ok,N/A MAR02090,MAM00413c <=> MAM00413l,ok,ok,ok,ok,N/A MAR02101,MAM00411c <=> MAM00411l,only when going backwards,ok,ok,ok,N/A -MAR03987,MAM01439e --> MAM01439l,ok,ok,ok,ok,N/A +MAR03987,MAM01439e --> MAM01439l,MAM01439e;MAM01439l,ok,ok,ok,N/A MAR04887,MAM02040c --> MAM02040l,ok,ok,ok,ok,N/A MAR04903,MAM02630c <=> MAM02630l,MAM02630l,ok,ok,ok,N/A MAR04907,MAM01285l + MAM01371c --> MAM01285c + MAM01371l,ok,ok,ok,ok,N/A @@ -7515,8 +7515,8 @@ MAR07985,MAM00402c <=> MAM00402r,only when going forwards,ok,ok,ok,N/A MAR07988,MAM01069c <=> MAM01069r,ok,ok,ok,ok,N/A MAR07989,MAM01070c <=> MAM01070r,only when going forwards,ok,ok,ok,N/A MAR08030,MAM02517r --> MAM02517c,ok,ok,ok,ok,N/A -MAR08058,MAM01765c <=> MAM01765r,only when going backwards,ok,ok,ok,N/A -MAR08060,MAM02150c <=> MAM02150r,only when going forwards,ok,ok,ok,N/A +MAR08058,MAM01765c <=> MAM01765r,MAM01765c;MAM01765r,ok,ok,ok,N/A +MAR08060,MAM02150c <=> MAM02150r,MAM02150c;MAM02150r,ok,ok,ok,N/A MAR08234,MAM02930c <=> MAM02930r,only when going backwards,ok,ok,ok,N/A MAR08236,MAM02929c <=> MAM02929r,only when going forwards,ok,ok,ok,N/A MAR08239,MAM02928c <=> MAM02928r,only when going backwards,ok,ok,ok,N/A @@ -7525,7 +7525,7 @@ MAR08350,MAM01685c <=> MAM01685r,only when going forwards,ok,ok,ok,N/A MAR08351,MAM02378r --> MAM02378c,ok,ok,ok,ok,N/A MAR08358,MAM01249c <=> MAM01249r,only when going forwards,ok,ok,ok,N/A MAR08369,MAM03110c + MAM03114r <=> MAM03110r + MAM03114c,MAM03110r,ok,ok,ok,N/A -MAR08382,MAM01964c --> MAM01964r,ok,ok,ok,ok,N/A +MAR08382,MAM01964c --> MAM01964r,MAM01964c;MAM01964r,ok,ok,ok,N/A MAR08526,MAM01513c <=> MAM01513r,only when going forwards,ok,ok,ok,N/A MAR08553,MAM02418c <=> MAM02418r,only when going forwards,ok,ok,ok,N/A MAR08594,MAM01338c <=> MAM01338r,ok,ok,ok,ok,N/A @@ -7548,19 +7548,19 @@ MAR08919,MAM02453r --> MAM02453c,ok,ok,ok,ok,N/A MAR08921,MAM02470c <=> MAM02470r,MAM02470r,ok,ok,ok,N/A MAR09177,MAM01800c <=> MAM01800r,only when going backwards,ok,ok,ok,N/A MAR09200,MAM03157c <=> MAM03157r,MAM03157r,ok,ok,ok,N/A -MAR09625,MAM00236r --> MAM00236c,ok,ok,ok,ok,N/A +MAR09625,MAM00236r --> MAM00236c,MAM00236r,ok,ok,ok,N/A MAR09626,MAM02946r <=> MAM02946c,only when going backwards,ok,ok,ok,N/A MAR09627,MAM02328r <=> MAM02328c,only when going backwards,ok,ok,ok,N/A MAR09628,MAM02027r <=> MAM02027c,only when going backwards,ok,ok,ok,N/A -MAR09629,MAM02022r <=> MAM02022c,only when going backwards,ok,ok,ok,N/A -MAR09630,MAM02434r <=> MAM02434c,only when going backwards,ok,ok,ok,N/A -MAR09631,MAM02462r <=> MAM02462c,only when going backwards,ok,ok,ok,N/A -MAR09632,MAM01665r <=> MAM01665c,only when going backwards,ok,ok,ok,N/A -MAR09633,MAM01687r <=> MAM01687c,only when going backwards,ok,ok,ok,N/A +MAR09629,MAM02022r <=> MAM02022c,MAM02022c;MAM02022r,ok,ok,ok,N/A +MAR09630,MAM02434r <=> MAM02434c,MAM02434c;MAM02434r,ok,ok,ok,N/A +MAR09631,MAM02462r <=> MAM02462c,MAM02462c;MAM02462r,ok,ok,ok,N/A +MAR09632,MAM01665r <=> MAM01665c,MAM01665c;MAM01665r,ok,ok,ok,N/A +MAR09633,MAM01687r <=> MAM01687c,MAM01687c;MAM01687r,ok,ok,ok,N/A MAR09634,MAM01798r <=> MAM01798c,only when going backwards,ok,ok,ok,N/A MAR09716,MAM01667r <=> MAM01667c,only when going backwards,ok,ok,ok,N/A MAR09724,MAM02728r --> MAM02728c,ok,ok,ok,ok,N/A -MAR09732,MAM02001r <=> MAM02001c,only when going forwards,ok,ok,ok,N/A +MAR09732,MAM02001r <=> MAM02001c,MAM02001c;MAM02001r,ok,ok,ok,N/A MAR07108,MAM01374e <=> ,only when going forwards,ok,ok,ok,N/A MAR07110,MAM02556e <=> ,only when going forwards,ok,ok,ok,N/A MAR07112,MAM01296e <=> ,only when going forwards,ok,ok,ok,N/A @@ -7587,7 +7587,7 @@ MAR09033,MAM02560e <=> ,only when going forwards,ok,ok,ok,N/A MAR09034,MAM01965e <=> ,ok,ok,ok,ok,N/A MAR09035,MAM02387e <=> ,ok,ok,ok,ok,N/A MAR09036,MAM02389e <=> ,ok,ok,ok,ok,N/A -MAR09037,MAM02746e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09037,MAM02746e <=> ,MAM02746e,ok,ok,ok,N/A MAR09038,MAM02125e <=> ,ok,ok,ok,ok,N/A MAR09039,MAM02184e <=> ,ok,ok,ok,ok,N/A MAR09040,MAM02360e <=> ,ok,ok,ok,ok,N/A @@ -7646,7 +7646,7 @@ MAR09095,MAM01290e <=> ,ok,ok,ok,ok,N/A MAR09096,MAM01822e <=> ,ok,ok,ok,ok,N/A MAR09097,MAM01641e <=> ,ok,ok,ok,ok,N/A MAR09098,MAM01638e <=> ,ok,ok,ok,ok,N/A -MAR09099,MAM01796e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09099,MAM01796e <=> ,MAM01796e,ok,ok,ok,N/A MAR09100,MAM01100e <=> ,ok,ok,ok,ok,N/A MAR09101,MAM02754e <=> ,ok,ok,ok,ok,N/A MAR09102,MAM02332e <=> ,ok,ok,ok,ok,N/A @@ -7712,7 +7712,7 @@ MAR09162,MAM02357e <=> ,ok,ok,ok,ok,N/A MAR09163,MAM02370e <=> ,ok,ok,ok,ok,N/A MAR09164,MAM02440e <=> ,ok,ok,ok,ok,N/A MAR09165,MAM02661e <=> ,ok,ok,ok,ok,N/A -MAR09166,MAM01438e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09166,MAM01438e <=> ,MAM01438e,ok,ok,ok,N/A MAR09167,MAM02394e <=> ,only when going forwards,ok,ok,ok,N/A MAR09168,MAM01962e <=> ,only when going forwards,ok,ok,ok,N/A MAR09169,MAM02885e <=> ,only when going forwards,ok,ok,ok,N/A @@ -7721,7 +7721,7 @@ MAR09172,MAM00549e <=> ,ok,ok,ok,ok,N/A MAR09201,MAM01588e <=> ,ok,ok,ok,ok,N/A MAR09202,MAM01356e <=> ,ok,ok,ok,ok,N/A MAR09203,MAM01758e <=> ,ok,ok,ok,ok,N/A -MAR09204,MAM02001e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09204,MAM02001e <=> ,MAM02001e,ok,ok,ok,N/A MAR09205,MAM00266e <=> ,only when going backwards,ok,ok,ok,N/A MAR09206,MAM00267e <=> ,ok,ok,ok,ok,N/A MAR09207,MAM00268e <=> ,ok,ok,ok,ok,N/A @@ -7731,7 +7731,7 @@ MAR09210,MAM00353e <=> ,only when going backwards,ok,ok,ok,N/A MAR09211,MAM00613e <=> ,only when going backwards,ok,ok,ok,N/A MAR09212,MAM00035e <=> ,only when going backwards,ok,ok,ok,N/A MAR09213,MAM01019e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09214,MAM00620e <=> ,ok,ok,ok,ok,N/A +MAR09214,MAM00620e <=> ,only when going forwards,ok,ok,ok,N/A MAR09215,MAM01415e <=> ,ok,ok,ok,ok,N/A MAR09216,MAM00648e <=> ,ok,ok,ok,ok,N/A MAR09217,MAM00665e <=> ,only when going backwards,ok,ok,ok,N/A @@ -7740,17 +7740,17 @@ MAR09219,MAM02354e <=> ,ok,ok,ok,ok,N/A MAR09220,MAM01433e <=> ,only when going backwards,ok,ok,ok,N/A MAR09221,MAM02325e <=> ,ok,ok,ok,ok,N/A MAR09222,MAM01633e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09223,MAM00998e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09223,MAM00998e <=> ,MAM00998e,ok,ok,ok,N/A MAR09224,MAM01003e <=> ,only when going backwards,ok,ok,ok,N/A MAR09225,MAM02182e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09226,MAM01007e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09226,MAM01007e <=> ,MAM01007e,ok,ok,ok,N/A MAR09227,MAM01021e <=> ,only when going backwards,ok,ok,ok,N/A MAR09228,MAM01033e <=> ,only when going backwards,ok,ok,ok,N/A MAR09229,MAM01069e <=> ,ok,ok,ok,ok,N/A MAR09230,MAM01070e <=> ,only when going backwards,ok,ok,ok,N/A MAR09231,MAM01071e <=> ,ok,ok,ok,ok,N/A MAR09232,MAM02691e <=> ,ok,ok,ok,ok,N/A -MAR09233,MAM01109e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09233,MAM01109e <=> ,MAM01109e,ok,ok,ok,N/A MAR09234,MAM01115e <=> ,ok,ok,ok,ok,N/A MAR09235,MAM02692e <=> ,ok,ok,ok,ok,N/A MAR09236,MAM02118e <=> ,ok,ok,ok,ok,N/A @@ -7763,7 +7763,7 @@ MAR09242,MAM01249e <=> ,ok,ok,ok,ok,N/A MAR09243,MAM01256e <=> ,ok,ok,ok,ok,N/A MAR09244,MAM03096e <=> ,only when going backwards,ok,ok,ok,N/A MAR09245,MAM03098e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09246,MAM02527e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09246,MAM02527e <=> ,MAM02527e,ok,ok,ok,N/A MAR09247,MAM01260e <=> ,ok,ok,ok,ok,N/A MAR09248,MAM02902e <=> ,only when going backwards,ok,ok,ok,N/A MAR09249,MAM02903e <=> ,only when going backwards,ok,ok,ok,N/A @@ -7782,18 +7782,18 @@ MAR09261,MAM01309e <=> ,only when going backwards,ok,ok,ok,N/A MAR09262,MAM01334e <=> ,ok,ok,ok,ok,N/A MAR09263,MAM01338e <=> ,ok,ok,ok,ok,N/A MAR09264,MAM01339e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09265,MAM01344e <=> ,only when going forwards,ok,ok,ok,N/A -MAR09266,MAM01326e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09267,MAM00002e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09265,MAM01344e <=> ,MAM01344e,ok,ok,ok,N/A +MAR09266,MAM01326e <=> ,MAM01326e,ok,ok,ok,N/A +MAR09267,MAM00002e <=> ,MAM00002e,ok,ok,ok,N/A MAR09268,MAM00580e <=> ,ok,ok,ok,ok,N/A MAR09269,MAM01361e <=> ,only when going forwards,ok,ok,ok,N/A -MAR09270,MAM02337e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09270,MAM02337e <=> ,MAM02337e,ok,ok,ok,N/A MAR09271,MAM01397e <=> ,ok,ok,ok,ok,N/A MAR09272,MAM01398e <=> ,ok,ok,ok,ok,N/A MAR09273,MAM01396e <=> ,ok,ok,ok,ok,N/A MAR09275,MAM01419e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09276,MAM01385e <=> ,only when going forwards,ok,ok,ok,N/A -MAR09277,MAM00001e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09276,MAM01385e <=> ,MAM01385e,ok,ok,ok,N/A +MAR09277,MAM00001e <=> ,MAM00001e,ok,ok,ok,N/A MAR09278,MAM01418e <=> ,MAM01418e,ok,ok,ok,N/A MAR09279,MAM01626e <=> ,ok,ok,ok,ok,N/A MAR09280,MAM01445e <=> ,ok,ok,ok,ok,N/A @@ -7805,9 +7805,9 @@ MAR09285,MAM01450e <=> ,ok,ok,ok,ok,N/A MAR09286,MAM01587e <=> ,only when going forwards,ok,ok,ok,N/A MAR09287,MAM01590e <=> ,ok,ok,ok,ok,N/A MAR09288,MAM01595e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09289,MAM01617e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09289,MAM01617e <=> ,MAM01617e,ok,ok,ok,N/A MAR09290,MAM01619e <=> ,ok,ok,ok,ok,N/A -MAR09291,MAM01632e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09291,MAM01632e <=> ,MAM01632e,ok,ok,ok,N/A MAR09292,MAM02348e <=> ,ok,ok,ok,ok,N/A MAR09293,MAM01615e <=> ,ok,ok,ok,ok,N/A MAR09294,MAM01614e <=> ,ok,ok,ok,ok,N/A @@ -7815,21 +7815,21 @@ MAR09295,MAM01630e <=> ,ok,ok,ok,ok,N/A MAR09296,MAM01668e <=> ,ok,ok,ok,ok,N/A MAR09297,MAM01666e <=> ,ok,ok,ok,ok,N/A MAR09298,MAM01098e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09299,MAM01647e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09299,MAM01647e <=> ,MAM01647e,ok,ok,ok,N/A MAR09300,MAM01669e <=> ,ok,ok,ok,ok,N/A MAR09301,MAM01655e <=> ,ok,ok,ok,ok,N/A MAR09302,MAM01659e <=> ,ok,ok,ok,ok,N/A MAR09303,MAM01700e <=> ,only when going backwards,ok,ok,ok,N/A MAR09304,MAM01695e <=> ,ok,ok,ok,ok,N/A MAR09305,MAM01671e <=> ,ok,ok,ok,ok,N/A -MAR09306,MAM01768e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09306,MAM01768e <=> ,MAM01768e,ok,ok,ok,N/A MAR09307,MAM00577e <=> ,ok,ok,ok,ok,N/A MAR09308,MAM01737e <=> ,only when going backwards,ok,ok,ok,N/A MAR09309,MAM01672e <=> ,ok,ok,ok,ok,N/A MAR09310,MAM01673e <=> ,ok,ok,ok,ok,N/A MAR09311,MAM01298e <=> ,ok,ok,ok,ok,N/A -MAR09312,MAM01765e <=> ,only when going forwards,ok,ok,ok,N/A -MAR09313,MAM02150e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09312,MAM01765e <=> ,MAM01765e,ok,ok,ok,N/A +MAR09313,MAM02150e <=> ,MAM02150e,ok,ok,ok,N/A MAR09314,MAM01787e <=> ,ok,ok,ok,ok,N/A MAR09315,MAM00402e <=> ,only when going backwards,ok,ok,ok,N/A MAR09316,MAM01795e <=> ,only when going backwards,ok,ok,ok,N/A @@ -7872,8 +7872,8 @@ MAR09352,MAM02034e <=> ,only when going forwards,ok,ok,ok,N/A MAR09353,MAM02037e <=> ,ok,ok,ok,ok,N/A MAR09354,MAM02041e <=> ,ok,ok,ok,ok,N/A MAR09355,MAM00986e <=> ,ok,ok,ok,ok,N/A -MAR09356,MAM03113e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09357,MAM01163e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09356,MAM03113e <=> ,MAM03113e,ok,ok,ok,N/A +MAR09357,MAM01163e <=> ,MAM01163e,ok,ok,ok,N/A MAR09358,MAM02159e <=> ,ok,ok,ok,ok,N/A MAR09359,MAM02161e <=> ,ok,ok,ok,ok,N/A MAR09360,MAM02167e <=> ,ok,ok,ok,ok,N/A @@ -7885,28 +7885,28 @@ MAR09365,MAM02364e <=> ,ok,ok,ok,ok,N/A MAR09366,MAM02366e <=> ,ok,ok,ok,ok,N/A MAR09367,MAM02418e <=> ,ok,ok,ok,ok,N/A MAR09368,MAM02369e <=> ,ok,ok,ok,ok,N/A -MAR09369,MAM02386e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09369,MAM02386e <=> ,MAM02386e,ok,ok,ok,N/A MAR09370,MAM02450e <=> ,ok,ok,ok,ok,N/A MAR09371,MAM02452e <=> ,ok,ok,ok,ok,N/A -MAR09372,MAM02470e <=> ,ok,ok,ok,ok,N/A +MAR09372,MAM02470e <=> ,only when going forwards,ok,ok,ok,N/A MAR09373,MAM02407e <=> ,ok,ok,ok,ok,N/A MAR09374,MAM00816e <=> ,only when going backwards,ok,ok,ok,N/A MAR09375,MAM02475e <=> ,ok,ok,ok,ok,N/A MAR09376,MAM02552e <=> ,ok,ok,ok,ok,N/A MAR09377,MAM02554e <=> ,only when going forwards,ok,ok,ok,N/A MAR09378,MAM02583e <=> ,ok,ok,ok,ok,N/A -MAR09379,MAM02587e <=> ,only when going forwards,ok,ok,ok,N/A -MAR09380,MAM02153e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09379,MAM02587e <=> ,MAM02587e,ok,ok,ok,N/A +MAR09380,MAM02153e <=> ,MAM02153e,ok,ok,ok,N/A MAR09381,MAM02609e <=> ,only when going backwards,ok,ok,ok,N/A MAR09382,MAM02620e <=> ,only when going backwards,ok,ok,ok,N/A MAR09383,MAM02631e <=> ,ok,ok,ok,ok,N/A MAR09384,MAM01244e <=> ,only when going backwards,ok,ok,ok,N/A MAR09385,MAM01245e <=> ,only when going backwards,ok,ok,ok,N/A MAR09386,MAM02147e <=> ,ok,ok,ok,ok,N/A -MAR09387,MAM02653e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09387,MAM02653e <=> ,MAM02653e,ok,ok,ok,N/A MAR09388,MAM00032e <=> ,ok,ok,ok,ok,N/A MAR09389,MAM00204e <=> ,ok,ok,ok,ok,N/A -MAR09390,MAM02712e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09390,MAM02712e <=> ,MAM02712e,ok,ok,ok,N/A MAR09391,MAM02722e <=> ,only when going backwards,ok,ok,ok,N/A MAR09392,MAM02744e <=> ,ok,ok,ok,ok,N/A MAR09393,MAM02769e <=> ,ok,ok,ok,ok,N/A @@ -7933,13 +7933,13 @@ MAR09415,MAM02943e <=> ,only when going forwards,ok,ok,ok,N/A MAR09416,MAM02945e <=> ,only when going forwards,ok,ok,ok,N/A MAR09417,MAM01745e <=> ,only when going forwards,ok,ok,ok,N/A MAR09418,MAM02961e <=> ,ok,ok,ok,ok,N/A -MAR09419,MAM02673e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09419,MAM02673e <=> ,MAM02673e,ok,ok,ok,N/A MAR09420,MAM02986e <=> ,ok,ok,ok,ok,N/A MAR09421,MAM02980e <=> ,ok,ok,ok,ok,N/A MAR09422,MAM02997e <=> ,ok,ok,ok,ok,N/A MAR09423,MAM02996e <=> ,ok,ok,ok,ok,N/A MAR09424,MAM02998e <=> ,ok,ok,ok,ok,N/A -MAR09425,MAM03001e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09425,MAM03001e <=> ,MAM03001e,ok,ok,ok,N/A MAR09426,MAM03039e <=> ,only when going forwards,ok,ok,ok,N/A MAR09427,MAM03052e <=> ,ok,ok,ok,ok,N/A MAR09428,MAM00734e <=> ,only when going backwards,ok,ok,ok,N/A @@ -7955,24 +7955,24 @@ MAR09437,MAM03118e <=> ,ok,ok,ok,ok,N/A MAR09438,MAM03121e <=> ,ok,ok,ok,ok,N/A MAR09439,MAM03123e <=> ,ok,ok,ok,ok,N/A MAR09440,MAM03130e <=> ,ok,ok,ok,ok,N/A -MAR09441,MAM03141e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09441,MAM03141e <=> ,MAM03141e,ok,ok,ok,N/A MAR09442,MAM03142e <=> ,only when going backwards,ok,ok,ok,N/A MAR09443,MAM00325e <=> ,only when going backwards,ok,ok,ok,N/A MAR09444,MAM00371e <=> ,only when going backwards,ok,ok,ok,N/A MAR09445,MAM00403e <=> ,ok,ok,ok,ok,N/A MAR09446,MAM00432e <=> ,ok,ok,ok,ok,N/A MAR09447,MAM01913e <=> ,only when going forwards,ok,ok,ok,N/A -MAR09448,MAM02445e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09448,MAM02445e <=> ,MAM02445e,ok,ok,ok,N/A MAR09449,MAM02723e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09450,MAM03154e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09450,MAM03154e <=> ,MAM03154e,ok,ok,ok,N/A MAR09451,MAM02191e <=> ,ok,ok,ok,ok,N/A MAR09452,MAM01788e <=> ,ok,ok,ok,ok,N/A MAR09453,MAM01800e <=> ,ok,ok,ok,ok,N/A MAR09454,MAM01740e <=> ,ok,ok,ok,ok,N/A -MAR09455,MAM01640e <=> ,only when going forwards,ok,ok,ok,N/A -MAR09456,MAM01286e <=> ,only when going forwards,ok,ok,ok,N/A -MAR09457,MAM01287e <=> ,only when going forwards,ok,ok,ok,N/A -MAR09458,MAM01743e <=> ,only when going forwards,ok,ok,ok,N/A +MAR09455,MAM01640e <=> ,MAM01640e,ok,ok,ok,N/A +MAR09456,MAM01286e <=> ,MAM01286e,ok,ok,ok,N/A +MAR09457,MAM01287e <=> ,MAM01287e,ok,ok,ok,N/A +MAR09458,MAM01743e <=> ,MAM01743e,ok,ok,ok,N/A MAR09460,MAM01621e <=> ,ok,ok,ok,ok,N/A MAR09461,MAM01966e <=> ,only when going backwards,ok,ok,ok,N/A MAR09462,MAM02155e <=> ,ok,ok,ok,ok,N/A @@ -7999,18 +7999,18 @@ MAR09699,MAM03131e <=> ,only when going backwards,ok,ok,ok,N/A MAR09700,MAM02516e <=> ,only when going backwards,ok,ok,ok,N/A MAR09701,MAM01603e <=> ,ok,ok,ok,ok,N/A MAR09702,MAM01604e <=> ,ok,ok,ok,ok,N/A -MAR09703,MAM02022e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09704,MAM01687e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09705,MAM01665e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09703,MAM02022e <=> ,MAM02022e,ok,ok,ok,N/A +MAR09704,MAM01687e <=> ,MAM01687e,ok,ok,ok,N/A +MAR09705,MAM01665e <=> ,MAM01665e,ok,ok,ok,N/A MAR09706,MAM01955e <=> ,only when going backwards,ok,ok,ok,N/A MAR09707,MAM00771e <=> ,only when going backwards,ok,ok,ok,N/A MAR09708,MAM02458e <=> ,only when going backwards,ok,ok,ok,N/A MAR09709,MAM01610e <=> ,ok,ok,ok,ok,N/A MAR09710,MAM01612e <=> ,ok,ok,ok,ok,N/A MAR09711,MAM01613e <=> ,ok,ok,ok,ok,N/A -MAR09712,MAM02462e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09712,MAM02462e <=> ,MAM02462e,ok,ok,ok,N/A MAR09713,MAM01006e <=> ,only when going backwards,ok,ok,ok,N/A -MAR09714,MAM02434e <=> ,only when going backwards,ok,ok,ok,N/A +MAR09714,MAM02434e <=> ,MAM02434e,ok,ok,ok,N/A MAR09715,MAM02926e <=> ,ok,ok,ok,ok,N/A MAR09721,MAM01730e <=> ,only when going backwards,ok,ok,ok,N/A MAR09729,MAM03161e <=> ,ok,ok,ok,ok,N/A @@ -8082,8 +8082,8 @@ MAR00094,MAM01371c + MAM01401e + MAM02040c + MAM02519e --> MAM01285c + MAM01401c MAR00095,MAM01401e + MAM02039c --> MAM01401c + MAM02039e,ok,ok,ok,MAR07666,N/A MAR00097,MAM01410c + MAM02039c <=> MAM01410m + MAM02039m,only when going backwards,ok,ok,ok,N/A MAR00098,MAM03484e --> MAM03484c,MAM03484c;MAM03484e,ok,ok,ok,N/A -MAR00099,MAM01380e <=> MAM01380c,ok,ok,ok,ok,N/A -MAR00100,MAM01380c <=> MAM01380r,only when going forwards,ok,ok,ok,N/A +MAR00099,MAM01380e <=> MAM01380c,only when going backwards,ok,ok,ok,N/A +MAR00100,MAM01380c <=> MAM01380r,MAM01380r,ok,ok,ok,N/A MAR00101,MAM00941r + MAM02039r + MAM02555r --> MAM00367r + MAM02554r,ok,ok,ok,ok,N/A MAR00102,MAM02411c <=> MAM02411m,ok,ok,ok,ok,N/A MAR00103,MAM00051c + MAM02348c <=> MAM01597c + MAM02117c,ok,ok,ok,ok,N/A @@ -8319,8 +8319,8 @@ MAR01385,MAM03620c --> MAM03620e,ok,ok,ok,ok,N/A MAR01386,MAM01986l + MAM02039l <=> MAM01986c + MAM02039c,ok,ok,ok,ok,N/A MAR01396,MAM01371c + MAM01986c + MAM02040c --> MAM01285c + MAM01986e + MAM02039c + MAM02751c,ok,ok,ok,MAR07737,N/A MAR01397,MAM01953x + MAM02187x --> MAM01806x + MAM02759x,ok,ok,ok,ok,N/A -MAR01399,MAM01734r + MAM02020r --> MAM01733r + MAM02039r + MAM03748r,MAM03748r,ok,ok,ok,N/A -MAR01400,MAM01734r + MAM02020r --> MAM01733r + MAM02039r + MAM03749r,MAM03749r,ok,ok,ok,N/A +MAR01399,MAM01734r + MAM02020r --> MAM01733r + MAM02039r + MAM03748r,MAM02020r;MAM03748r,ok,ok,ok,N/A +MAR01400,MAM01734r + MAM02020r --> MAM01733r + MAM02039r + MAM03749r,MAM02020r;MAM03749r,ok,ok,ok,N/A MAR01435,MAM02674r --> MAM02674c,ok,ok,ok,ok,N/A MAR01438,MAM00051c <=> MAM00051x,ok,ok,ok,ok,N/A MAR01439,MAM01597m + MAM02109m <=> MAM02110m + MAM02348m,MAM02109m;MAM02110m,ok,ok,ok,N/A @@ -8365,8 +8365,8 @@ MAR01506,MAM00291c + MAM02684c --> MAM00656c + MAM02838c,ok,ok,ok,ok,N/A MAR01507,MAM01232c + MAM02684c --> MAM00656c + MAM03315c,ok,ok,ok,ok,N/A MAR01508,MAM01066r + MAM02039r + MAM02555r + MAM02630r --> MAM01189r + 2 MAM02040r + MAM02554r,ok,ok,ok,ok,N/A MAR01510,MAM02039r + MAM02343r + MAM02555r + MAM02630r --> 2 MAM02040r + MAM02554r + MAM02805r,ok,ok,ok,ok,N/A -MAR01511,MAM02001r + MAM03749r --> MAM02022r + MAM03750r,MAM03749r;MAM03750r,ok,ok,ok,N/A -MAR01513,MAM02461r + MAM02685r --> MAM00236r + MAM03749r,MAM03749r,ok,ok,ok,N/A +MAR01511,MAM02001r + MAM03749r --> MAM02022r + MAM03750r,MAM02001r;MAM02022r;MAM03749r;MAM03750r,ok,ok,ok,N/A +MAR01513,MAM02461r + MAM02685r --> MAM00236r + MAM03749r,MAM00236r;MAM02461r;MAM03749r,ok,ok,ok,N/A MAR01514,MAM10006e <=> MAM10006c,ok,ok,ok,ok,N/A MAR01517,MAM00184m + MAM02444m <=> MAM01597m + MAM02442m,MAM00184m;MAM02442m,ok,ok,ok,N/A MAR01518,MAM01371c + MAM02040c + MAM02407c --> MAM01285c + MAM02039c + MAM02407e + MAM02751c,ok,ok,ok,MAR08922,N/A @@ -9043,7 +9043,7 @@ MAR04119,MAM02044e <=> ,ok,ok,ok,ok,N/A MAR04129,MAM02753e <=> ,ok,ok,ok,ok,N/A MAR04138,MAM02802e <=> ,ok,ok,ok,ok,N/A MAR04140,MAM00186e <=> ,ok,ok,ok,ok,N/A -MAR04142,MAM01439e <=> ,ok,ok,ok,ok,N/A +MAR04142,MAM01439e <=> ,MAM01439e,ok,ok,ok,N/A MAR04146,MAM02965e <=> ,ok,ok,ok,ok,N/A MAR04148,MAM02000e <=> ,ok,ok,ok,ok,N/A MAR04150,MAM02966e <=> ,ok,ok,ok,ok,N/A @@ -9086,8 +9086,8 @@ MAR04305,MAM02563e <=> ,ok,ok,ok,ok,N/A MAR04307,MAM02562e <=> ,ok,ok,ok,ok,N/A MAR04309,MAM01348e <=> ,ok,ok,ok,ok,N/A MAR04311,MAM01347e <=> ,ok,ok,ok,ok,N/A -MAR04322,MAM02446e <=> ,ok,ok,ok,ok,N/A -MAR04325,MAM02448e <=> ,ok,ok,ok,ok,N/A +MAR04322,MAM02446e <=> ,only when going forwards,ok,ok,ok,N/A +MAR04325,MAM02448e <=> ,MAM02448e,ok,ok,ok,N/A MAR04327,MAM03330e <=> ,only when going forwards,ok,ok,ok,N/A MAR04334,MAM03525e <=> ,only when going backwards,ok,ok,ok,N/A MAR04337,MAM00570e <=> ,ok,ok,ok,ok,N/A @@ -9137,7 +9137,7 @@ MAR04566,MAM03263m <=> MAM03263c,only when going backwards,ok,ok,ok,N/A MAR04569,MAM02348c + MAM03979c <=> MAM01597c + MAM03980c,MAM03979c;MAM03980c,ok,ok,ok,N/A MAR04571,MAM02348c + MAM03263c <=> MAM01597c + MAM03264c,only when going backwards,ok,ok,ok,N/A MAR04578,MAM03267m <=> MAM03267c,only when going backwards,ok,ok,ok,N/A -MAR04581,MAM02348c + MAM03974c <=> MAM01597c + MAM03975c,only when going forwards,ok,ok,ok,N/A +MAR04581,MAM02348c + MAM03974c <=> MAM01597c + MAM03975c,MAM03974c;MAM03975c,ok,ok,ok,N/A MAR04598,MAM02348c + MAM03267c <=> MAM01597c + MAM03268c,only when going backwards,ok,ok,ok,N/A MAR04610,MAM00178c + MAM02348c <=> MAM01597c + MAM03262c,ok,ok,ok,ok,N/A MAR04613,MAM02348c + MAM03216c <=> MAM01597c + MAM03217c,only when going backwards,ok,ok,ok,N/A @@ -9207,7 +9207,7 @@ MAR04927,MAM01583e <=> ,ok,ok,ok,ok,N/A MAR04929,MAM01373e <=> ,ok,ok,ok,ok,N/A MAR04936,MAM03560e <=> ,only when going backwards,ok,ok,ok,N/A MAR04943,MAM03706e <=> ,only when going backwards,ok,ok,ok,N/A -MAR04950,MAM03975e <=> ,only when going forwards,ok,ok,ok,N/A +MAR04950,MAM03975e <=> ,MAM03975e,ok,ok,ok,N/A MAR04965,MAM03980e <=> ,MAM03980e,ok,ok,ok,N/A MAR04968,MAM00039x + MAM01597x + MAM02040x + MAM02552x --> MAM01261x + MAM02039x + MAM02553x + MAM02644x,ok,ok,ok,ok,N/A MAR04970,MAM00678m + MAM02039m + MAM02555m --> MAM02554m + MAM03035m,ok,ok,ok,ok,N/A @@ -9695,13 +9695,13 @@ MAR09939,MAM02125c + MAM02877c <=> MAM02039c + MAM02871c + MAM03247c,ok,ok,ok,ok MAR09940,MAM01420c + MAM02426c <=> MAM02039c + MAM02751c + MAM03681c,ok,ok,ok,ok,N/A MAR09941,MAM01986c + MAM02721c --> MAM01597c + MAM02039c + MAM03862c,ok,ok,ok,ok,N/A MAR09942,MAM02040l + MAM04077l --> MAM01450l + MAM01932l + MAM02039l,ok,ok,ok,ok,N/A -MAR09943,MAM02040l + MAM04076l --> MAM01450l + MAM02039l + MAM02387l,ok,ok,ok,ok,N/A +MAR09943,MAM02040l + MAM04076l --> MAM01450l + MAM02039l + MAM02387l,MAM04076l,ok,ok,ok,N/A MAR09944,MAM02040l + MAM04075l --> MAM01450l + MAM01585l + MAM02039l,ok,ok,ok,ok,N/A MAR09945,MAM02040l + MAM04079l --> MAM01450l + MAM01784l + MAM02039l,ok,ok,ok,ok,N/A MAR09946,MAM02040l + MAM04078l --> MAM01362l + MAM01450l + MAM02039l,ok,ok,ok,ok,N/A MAR09947,MAM02040l + MAM04080l --> MAM01450l + MAM01689l + MAM02039l,ok,ok,ok,ok,N/A MAR09948,MAM00009c + MAM02040c --> MAM01597c + MAM02039c + MAM03569c,ok,ok,ok,ok,N/A -MAR09950,MAM02040c + MAM03974c --> MAM01597c + MAM02039c + MAM03976c,ok,ok,ok,ok,N/A +MAR09950,MAM02040c + MAM03974c --> MAM01597c + MAM02039c + MAM03976c,MAM03974c,ok,ok,ok,N/A MAR09951,MAM02040c + MAM02912c --> MAM01513c + MAM02039c + MAM03619c,ok,ok,ok,ok,N/A MAR09952,MAM02040c + MAM03401c <=> MAM01252c + MAM02426c,ok,ok,ok,ok,N/A MAR09953,MAM02471c + MAM02819c <=> MAM01307c + MAM03276c,only when going backwards,ok,ok,ok,N/A @@ -9942,7 +9942,7 @@ MAR10297,MAM03832e <=> ,ok,ok,ok,ok,N/A MAR10298,MAM03833e <=> ,ok,ok,ok,ok,N/A MAR10299,MAM03834e <=> ,ok,ok,ok,ok,N/A MAR10300,MAM03835e <=> ,ok,ok,ok,ok,N/A -MAR10301,MAM02381e <=> ,only when going forwards,ok,ok,ok,N/A +MAR10301,MAM02381e <=> ,MAM02381e,ok,ok,ok,N/A MAR10302,MAM03838e <=> ,ok,ok,ok,ok,N/A MAR10303,MAM03839e <=> ,ok,ok,ok,ok,N/A MAR10304,MAM03840e <=> ,ok,ok,ok,ok,N/A @@ -9991,7 +9991,7 @@ MAR10346,MAM02995e <=> ,ok,ok,ok,ok,N/A MAR10347,MAM03124e <=> ,ok,ok,ok,ok,N/A MAR10348,MAM00270e <=> ,ok,ok,ok,ok,N/A MAR10349,MAM04075e <=> ,only when going forwards,ok,ok,ok,N/A -MAR10350,MAM04076e <=> ,only when going forwards,ok,ok,ok,N/A +MAR10350,MAM04076e <=> ,MAM04076e,ok,ok,ok,N/A MAR10351,MAM04077e <=> ,only when going forwards,ok,ok,ok,N/A MAR10352,MAM04078e <=> ,only when going forwards,ok,ok,ok,N/A MAR10353,MAM04079e <=> ,only when going forwards,ok,ok,ok,N/A @@ -10035,7 +10035,7 @@ MAR10390,3 MAM02519c + MAM02532c <=> 3 MAM02519e + MAM02532e,ok,ok,ok,ok,N/A MAR10391,MAM02497c <=> MAM02497e,ok,ok,ok,ok,N/A MAR10392,MAM02039c + MAM02633c <=> MAM02039e + MAM02633e,ok,ok,ok,ok,N/A MAR10393,MAM02720c <=> MAM02720e,ok,ok,ok,ok,N/A -MAR10394,MAM02381c <=> MAM02381e,only when going forwards,ok,ok,ok,N/A +MAR10394,MAM02381c <=> MAM02381e,MAM02381c;MAM02381e,ok,ok,ok,N/A MAR10395,MAM02795c <=> MAM01892c,ok,ok,ok,ok,N/A MAR10396,MAM00916c <=> MAM00916e,ok,ok,ok,ok,N/A MAR10397,MAM02868c <=> MAM02868m,ok,ok,ok,ok,N/A @@ -10043,7 +10043,7 @@ MAR10398,MAM02868c <=> MAM02868e,ok,ok,ok,ok,N/A MAR10399,MAM03923c <=> MAM03923e,ok,ok,ok,ok,N/A MAR10400,MAM03954c <=> MAM03954e,ok,ok,ok,ok,N/A MAR10401,MAM01371c + MAM02040c + MAM03976c --> MAM01285c + MAM02039c + MAM02751c + MAM03976e,ok,ok,ok,ok,N/A -MAR10402,MAM03976c <=> MAM03976e,ok,ok,ok,ok,N/A +MAR10402,MAM03976c <=> MAM03976e,only when going forwards,ok,ok,ok,N/A MAR10403,MAM01261m + MAM02993m --> MAM01597m + MAM02039m + MAM03406m,ok,ok,ok,ok,N/A MAR10404,MAM01371c + MAM02040c + MAM02992c --> MAM01285c + MAM02039c + MAM02751c + MAM02992e,ok,ok,ok,ok,N/A MAR10405,MAM02517c <=> MAM02517e,ok,ok,ok,ok,N/A @@ -10110,7 +10110,7 @@ MAR10470,MAM03231e <=> MAM03232c,ok,ok,ok,ok,N/A MAR10472,MAM03215e <=> ,MAM03215e,ok,ok,ok,N/A MAR10473,MAM03231e <=> ,ok,ok,ok,ok,N/A MAR10474,MAM02123e <=> ,ok,ok,ok,ok,N/A -MAR10475,MAM01380e <=> ,ok,ok,ok,ok,N/A +MAR10475,MAM01380e <=> ,only when going forwards,ok,ok,ok,N/A MAR10476,MAM03836e <=> ,only when going forwards,ok,ok,ok,N/A MAR10477,MAM03837e <=> ,only when going backwards,ok,ok,ok,N/A MAR10478,MAM03703e <=> ,MAM03703e,ok,ok,ok,N/A @@ -10119,7 +10119,7 @@ MAR10480,MAM02407e <=> MAM02407c,ok,ok,ok,ok,N/A MAR10481,MAM03039e <=> MAM03039c,only when going backwards,ok,ok,ok,N/A MAR10482,MAM00400c <=> MAM00400e,ok,ok,ok,ok,N/A MAR10483,MAM02832c <=> MAM02832e,ok,ok,ok,ok,N/A -MAR10484,MAM02451e <=> MAM02451c,ok,ok,ok,ok,N/A +MAR10484,MAM02451e <=> MAM02451c,only when going backwards,ok,ok,ok,N/A MAR10485,MAM03715c <=> MAM03715e,ok,ok,ok,ok,N/A MAR10486,MAM03630c <=> MAM03630e,ok,ok,ok,ok,N/A MAR10487,MAM03896c <=> MAM03896e,ok,ok,ok,ok,N/A @@ -10863,7 +10863,7 @@ MAR11224,MAM02039c + MAM02555c + MAM02630c + MAM02718c --> MAM02040c + MAM02554c MAR11225,MAM02039c + MAM02555c + MAM02630c + MAM03099c --> MAM01736c + MAM02040c + MAM02554c,ok,ok,ok,ok,N/A MAR11226,MAM03807e <=> MAM03807c,MAM03807c;MAM03807e,ok,ok,ok,N/A MAR11227,MAM04077e <=> MAM04077c,only when going backwards,ok,ok,ok,N/A -MAR11228,MAM04076e <=> MAM04076c,only when going backwards,ok,ok,ok,N/A +MAR11228,MAM04076e <=> MAM04076c,MAM04076c;MAM04076e,ok,ok,ok,N/A MAR11229,MAM04075e <=> MAM04075c,only when going backwards,ok,ok,ok,N/A MAR11230,MAM04079e <=> MAM04079c,only when going backwards,ok,ok,ok,N/A MAR11231,MAM04078e <=> MAM04078c,only when going backwards,ok,ok,ok,N/A @@ -10910,12 +10910,12 @@ MAR11272,MAM00105e <=> MAM00105c,ok,ok,ok,ok,N/A MAR11274,MAM02639e <=> MAM02639c,ok,ok,ok,ok,N/A MAR11276,MAM02411e <=> MAM02411c,ok,ok,ok,ok,N/A MAR11277,MAM02940e <=> MAM02940c,ok,ok,ok,ok,N/A -MAR11278,MAM03975e <=> MAM03975c,only when going backwards,ok,ok,ok,N/A +MAR11278,MAM03975e <=> MAM03975c,MAM03975c;MAM03975e,ok,ok,ok,N/A MAR11279,MAM03980e <=> MAM03980c,MAM03980c;MAM03980e,ok,ok,ok,N/A MAR11280,MAM02974e <=> MAM02974c,ok,ok,ok,ok,N/A MAR11281,MAM02908e <=> ,ok,ok,ok,ok,N/A MAR11282,MAM04077c <=> MAM04077l,only when going backwards,ok,ok,ok,N/A -MAR11283,MAM04076c <=> MAM04076l,only when going backwards,ok,ok,ok,N/A +MAR11283,MAM04076c <=> MAM04076l,MAM04076c;MAM04076l,ok,ok,ok,N/A MAR11284,MAM04075c <=> MAM04075l,only when going backwards,ok,ok,ok,N/A MAR11285,MAM04079c <=> MAM04079l,only when going backwards,ok,ok,ok,N/A MAR11286,MAM04078c <=> MAM04078l,only when going backwards,ok,ok,ok,N/A @@ -11438,9 +11438,9 @@ MAR11827,MAM02942e <=> ,ok,ok,ok,ok,N/A MAR11828,MAM00373r + MAM01371r + MAM02040r --> MAM00373c + MAM01285r + MAM02039r + MAM02751r,ok,ok,ok,ok,N/A MAR11829,MAM00373c + MAM01371c + MAM02040c --> MAM00373e + MAM01285c + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A MAR11830,MAM00373e <=> ,only when going backwards,ok,ok,ok,N/A -MAR11831,MAM01767r <=> MAM01767c,only when going backwards,ok,ok,ok,N/A -MAR11832,MAM01767c <=> MAM01767e,only when going backwards,ok,ok,ok,N/A -MAR11833,MAM01767e <=> ,only when going backwards,ok,ok,ok,N/A +MAR11831,MAM01767r <=> MAM01767c,MAM01767c;MAM01767r,ok,ok,ok,N/A +MAR11832,MAM01767c <=> MAM01767e,MAM01767c;MAM01767e,ok,ok,ok,N/A +MAR11833,MAM01767e <=> ,MAM01767e,ok,ok,ok,N/A MAR11834,MAM00324r + MAM01371r + MAM02040r --> MAM00324c + MAM01285r + MAM02039r + MAM02751r,ok,ok,ok,ok,N/A MAR11835,MAM00324c + MAM01371c + MAM02040c --> MAM00324e + MAM01285c + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A MAR11836,MAM00324e <=> ,only when going backwards,ok,ok,ok,N/A @@ -11452,9 +11452,9 @@ MAR11841,MAM02933c --> MAM02933e,ok,ok,ok,ok,N/A MAR11842,MAM02933e <=> ,only when going backwards,ok,ok,ok,N/A MAR11843,MAM01740x + MAM02039c <=> MAM01740c + MAM02039x,ok,ok,ok,ok,N/A MAR11844,MAM01740c + MAM02039e <=> MAM01740e + MAM02039c,ok,ok,ok,ok,N/A -MAR11845,MAM01101x <=> MAM01101c,only when going backwards,ok,ok,ok,N/A -MAR11846,MAM01101c <=> MAM01101e,only when going backwards,ok,ok,ok,N/A -MAR11847,MAM01101e <=> ,only when going backwards,ok,ok,ok,N/A +MAR11845,MAM01101x <=> MAM01101c,MAM01101c;MAM01101x,ok,ok,ok,N/A +MAR11846,MAM01101c <=> MAM01101e,MAM01101c;MAM01101e,ok,ok,ok,N/A +MAR11847,MAM01101e <=> ,MAM01101e,ok,ok,ok,N/A MAR11848,MAM00971e <=> ,only when going backwards,ok,ok,ok,N/A MAR11849,MAM01371c + MAM01660c + MAM02040c --> MAM01285c + MAM01660e + MAM02039c + MAM02751c,ok,ok,ok,ok,N/A MAR11850,MAM01660e <=> ,only when going backwards,ok,ok,ok,N/A @@ -11582,9 +11582,9 @@ MAR11971,MAM01220e <=> ,only when going backwards,ok,ok,ok,N/A MAR11972,MAM02336c --> MAM02336e,ok,ok,ok,ok,N/A MAR11973,MAM01841c <=> MAM01841e,ok,ok,ok,ok,N/A MAR11974,MAM01841e <=> ,ok,ok,ok,ok,N/A -MAR11975,MAM01601e <=> ,only when going forwards,ok,ok,ok,N/A -MAR11976,MAM01601e <=> MAM01601c,only when going backwards,ok,ok,ok,N/A -MAR11977,MAM01601c <=> MAM01601r,only when going backwards,ok,ok,ok,N/A +MAR11975,MAM01601e <=> ,MAM01601e,ok,ok,ok,N/A +MAR11976,MAM01601e <=> MAM01601c,MAM01601c;MAM01601e,ok,ok,ok,N/A +MAR11977,MAM01601c <=> MAM01601r,MAM01601c;MAM01601r,ok,ok,ok,N/A MAR11978,MAM01073e <=> ,only when going backwards,ok,ok,ok,N/A MAR11979,MAM01073c <=> MAM01073e,only when going backwards,ok,ok,ok,N/A MAR11980,MAM01073x <=> MAM01073c,only when going backwards,ok,ok,ok,N/A @@ -12293,7 +12293,7 @@ MAR12687,MAM03770e <=> ,ok,ok,ok,ok,N/A MAR12688,MAM03780e <=> ,only when going backwards,ok,ok,ok,N/A MAR12689,MAM03781e <=> ,ok,ok,ok,ok,N/A MAR12690,MAM03782e <=> ,ok,ok,ok,ok,N/A -MAR12691,MAM03783e <=> ,ok,ok,ok,ok,N/A +MAR12691,MAM03783e <=> ,only when going forwards,ok,ok,ok,N/A MAR12692,MAM03784e <=> ,ok,ok,ok,ok,N/A MAR12693,MAM03801e <=> ,ok,ok,ok,ok,N/A MAR12694,MAM03799e <=> ,only when going backwards,ok,ok,ok,N/A @@ -12401,9 +12401,9 @@ MAR12795,MAM03781c <=> MAM03781e,ok,ok,ok,ok,N/A MAR12796,MAM02871r + MAM03783r --> MAM02877r + MAM03781r,ok,ok,ok,ok,N/A MAR12797,MAM02039c + MAM03784c <=> MAM02040c + MAM03782c,ok,ok,ok,ok,N/A MAR12798,MAM03782c <=> MAM03782e,ok,ok,ok,ok,N/A -MAR12799,MAM03783c <=> MAM03783e,ok,ok,ok,ok,N/A +MAR12799,MAM03783c <=> MAM03783e,only when going forwards,ok,ok,ok,N/A MAR12800,MAM03784c <=> MAM03784e,ok,ok,ok,ok,N/A -MAR12801,MAM02554c + MAM02587c --> MAM02039c + MAM02555c + MAM03783c,ok,ok,ok,ok,N/A +MAR12801,MAM02554c + MAM02587c --> MAM02039c + MAM02555c + MAM03783c,MAM02587c,ok,ok,ok,N/A MAR12802,MAM03801c + MAM04059c --> MAM02039c + MAM03106c + MAM03799c,ok,ok,ok,ok,N/A MAR12803,MAM03801c + MAM04059c --> MAM02039c + MAM03106c + MAM03800c,ok,ok,ok,ok,N/A MAR12804,MAM03799c <=> MAM03799e,only when going backwards,ok,ok,ok,N/A diff --git a/data/testResults/macaw_summary.md b/data/testResults/macaw_summary.md new file mode 100644 index 00000000..26f5f7ab --- /dev/null +++ b/data/testResults/macaw_summary.md @@ -0,0 +1,10 @@ +Starting dead-end test... + - Found 1514 dead-end metabolites. + - Found 1319 reactions incapable of sustaining steady-state fluxes in either direction due to these dead-ends. + - Found 1977 reversible reactions that can only carry steady-state fluxes in a single direction due to dead-ends. +Starting duplicate test... + - Skipping redox duplicates because no redox_pairs and/or proton_ids were provided. + - Found 447 reactions that were some type of duplicate: + - 0 were completely identical to at least one other reaction. + - 13 involve the same metabolites but go in the opposite direction or have the opposite reversibility as at least one other reaction. + - 447 involve the same metabolites but with different coefficients as at least one other reaction. \ No newline at end of file