diff --git a/RoomsEyeView/Logic/vtkSlicerRoomsEyeViewModuleLogic.cxx b/RoomsEyeView/Logic/vtkSlicerRoomsEyeViewModuleLogic.cxx
index 74760ded..371fb5ed 100644
--- a/RoomsEyeView/Logic/vtkSlicerRoomsEyeViewModuleLogic.cxx
+++ b/RoomsEyeView/Logic/vtkSlicerRoomsEyeViewModuleLogic.cxx
@@ -534,7 +534,7 @@ vtkSlicerRoomsEyeViewModuleLogic::LoadTreatmentMachine(vtkMRMLRoomsEyeViewNode*
 
 //----------------------------------------------------------------------------
 std::vector<vtkSlicerRoomsEyeViewModuleLogic::TreatmentMachinePartType>
-vtkSlicerRoomsEyeViewModuleLogic::SetupTreatmentMachineModels(vtkMRMLRoomsEyeViewNode* parameterNode)
+vtkSlicerRoomsEyeViewModuleLogic::SetupTreatmentMachineModels(vtkMRMLRoomsEyeViewNode* parameterNode, bool forceEnableCollisionDetection/*=false*/)
 {
   vtkMRMLScene* scene = this->GetMRMLScene();
   if (!scene)
@@ -649,24 +649,24 @@ vtkSlicerRoomsEyeViewModuleLogic::SetupTreatmentMachineModels(vtkMRMLRoomsEyeVie
   }
 
   // Disable collision detection if product of number of triangles of the two models is above threshold
-  if (loadedPartsNumTriangles[Gantry] * loadedPartsNumTriangles[TableTop] > MAX_TRIANGLE_NUMBER_PRODUCT_FOR_COLLISIONS)
+  if (loadedPartsNumTriangles[Gantry] * loadedPartsNumTriangles[TableTop] > MAX_TRIANGLE_NUMBER_PRODUCT_FOR_COLLISIONS && !forceEnableCollisionDetection)
   {
-    vtkWarningMacro("Collision detection between gantry and table top is disabled due to too many combined triangles (product = "
-      << loadedPartsNumTriangles[Gantry] * loadedPartsNumTriangles[TableTop] << ")");
+    vtkWarningMacro("Too many combined triangles (product = " << loadedPartsNumTriangles[Gantry] * loadedPartsNumTriangles[TableTop]
+      << ") detected between gantry and table top. Collision detection may take a very long time.");
     this->GantryTableTopCollisionDetection->SetInputData(0, nullptr);
     this->GantryTableTopCollisionDetection->SetInputData(1, nullptr);
   }
-  if (loadedPartsNumTriangles[Gantry] * loadedPartsNumTriangles[PatientSupport] > MAX_TRIANGLE_NUMBER_PRODUCT_FOR_COLLISIONS)
+  if (loadedPartsNumTriangles[Gantry] * loadedPartsNumTriangles[PatientSupport] > MAX_TRIANGLE_NUMBER_PRODUCT_FOR_COLLISIONS && !forceEnableCollisionDetection)
   {
-    vtkWarningMacro("Collision detection between gantry and patient support is disabled due to too many combined triangles (product = "
-      << loadedPartsNumTriangles[Gantry] * loadedPartsNumTriangles[PatientSupport] << ")");
+    vtkWarningMacro("Too many combined triangles (product = " << loadedPartsNumTriangles[Gantry] * loadedPartsNumTriangles[PatientSupport]
+      << ") detected between gantry and patient support. Collision detection may take a very long time.");
     this->GantryPatientSupportCollisionDetection->SetInputData(0, nullptr);
     this->GantryPatientSupportCollisionDetection->SetInputData(1, nullptr);
   }
-  if (loadedPartsNumTriangles[Collimator] * loadedPartsNumTriangles[TableTop] > MAX_TRIANGLE_NUMBER_PRODUCT_FOR_COLLISIONS)
+  if (loadedPartsNumTriangles[Collimator] * loadedPartsNumTriangles[TableTop] > MAX_TRIANGLE_NUMBER_PRODUCT_FOR_COLLISIONS && !forceEnableCollisionDetection)
   {
-    vtkWarningMacro("Collision detection between collimator and table top is disabled due to too many combined triangles (product = "
-      << loadedPartsNumTriangles[Collimator] * loadedPartsNumTriangles[TableTop] << ")");
+    vtkWarningMacro("Too many combined triangles (product = " << loadedPartsNumTriangles[Collimator] * loadedPartsNumTriangles[TableTop]
+      << ") detected between collimator and table top. Collision detection may take a very long time.");
     this->CollimatorTableTopCollisionDetection->SetInputData(0, nullptr);
     this->CollimatorTableTopCollisionDetection->SetInputData(1, nullptr);
   }
diff --git a/RoomsEyeView/Logic/vtkSlicerRoomsEyeViewModuleLogic.h b/RoomsEyeView/Logic/vtkSlicerRoomsEyeViewModuleLogic.h
index 2c1f1c8a..30bdf346 100644
--- a/RoomsEyeView/Logic/vtkSlicerRoomsEyeViewModuleLogic.h
+++ b/RoomsEyeView/Logic/vtkSlicerRoomsEyeViewModuleLogic.h
@@ -81,8 +81,11 @@ class VTK_SLICER_ROOMSEYEVIEW_LOGIC_EXPORT vtkSlicerRoomsEyeViewModuleLogic :
   /// \return List of parts that were successfully set up.
   std::vector<TreatmentMachinePartType> LoadTreatmentMachine(vtkMRMLRoomsEyeViewNode* parameterNode);
   /// Set up the IEC transforms and model properties on the treatment machine models.
+  /// \param forceEnableCollisionDetection Enable collision detection between parts even if calculation is potentially
+  ///        lengthy absed on the number of triangles of the parts.
   /// \return List of parts that were successfully set up.
-  std::vector<TreatmentMachinePartType> SetupTreatmentMachineModels(vtkMRMLRoomsEyeViewNode* parameterNode);
+  std::vector<TreatmentMachinePartType> SetupTreatmentMachineModels(
+    vtkMRMLRoomsEyeViewNode* parameterNode, bool forceEnableCollisionDetection=false);
   /// Create or get transforms taking part in the IEC logic and additional devices, and build the transform hierarchy
   void BuildRoomsEyeViewTransformHierarchy();
 
diff --git a/RoomsEyeView/qSlicerRoomsEyeViewModuleWidget.cxx b/RoomsEyeView/qSlicerRoomsEyeViewModuleWidget.cxx
index 4e41c1a9..60f0d38e 100644
--- a/RoomsEyeView/qSlicerRoomsEyeViewModuleWidget.cxx
+++ b/RoomsEyeView/qSlicerRoomsEyeViewModuleWidget.cxx
@@ -592,7 +592,7 @@ void qSlicerRoomsEyeViewModuleWidget::onLoadTreatmentMachineButtonClicked()
 
   // Warn the user if collision detection is disabled for certain part pairs
   QString disabledCollisionDetectionMessage(
-    "Collision detection has been disabled for the following part pairs due to high triangle numbers:\n\n");
+    tr("Collision detection for the following part pairs may take very long due to high triangle numbers:\n\n"));
   bool collisionDetectionDisabled = false;
   if (d->logic()->GetGantryTableTopCollisionDetection()->GetInputData(0) == nullptr)
   {
@@ -609,9 +609,22 @@ void qSlicerRoomsEyeViewModuleWidget::onLoadTreatmentMachineButtonClicked()
     disabledCollisionDetectionMessage.append("Collimator-TableTop\n");
     collisionDetectionDisabled = true;
   }
+  disabledCollisionDetectionMessage.append(tr("\nWhat would you like to do?"));
   if (collisionDetectionDisabled)
   {
-    QMessageBox::warning(this, tr("Collision detection disabled"), disabledCollisionDetectionMessage);
+    ctkMessageBox* existingMachineMsgBox = new ctkMessageBox(this);
+    existingMachineMsgBox->setWindowTitle(tr("Collision detection might take too long"));
+    existingMachineMsgBox->setText(disabledCollisionDetectionMessage);
+    existingMachineMsgBox->addButton(tr("Disable on these part pairs"), QMessageBox::AcceptRole);
+    existingMachineMsgBox->addButton(tr("Calculate anyway"), QMessageBox::RejectRole);
+    existingMachineMsgBox->setIcon(QMessageBox::Warning);
+    existingMachineMsgBox->exec();
+    int resultCode = existingMachineMsgBox->buttonRole(existingMachineMsgBox->clickedButton());
+    if (resultCode == QMessageBox::RejectRole)
+    {
+      // Set up treatment machine models again but make sure collision detection is not disabled between any parts
+      d->logic()->SetupTreatmentMachineModels(paramNode, true);
+    }
   }
 
   // Set treatment machine dependent properties  //TODO: Use degrees of freedom from JSON
@@ -1058,7 +1071,14 @@ void qSlicerRoomsEyeViewModuleWidget::checkForCollisions()
   }
   else
   {
-    d->CollisionDetectionStatusLabel->setText(QString::fromStdString("No collisions detected"));
+    QString noCollisionsMessage(tr("No collisions detected"));
+    if (d->logic()->GetGantryTableTopCollisionDetection()->GetInputData(0) == nullptr
+     || d->logic()->GetGantryPatientSupportCollisionDetection()->GetInputData(0) == nullptr
+     || d->logic()->GetCollimatorTableTopCollisionDetection()->GetInputData(0) == nullptr)
+    {
+      noCollisionsMessage.append(tr(" (excluding certain parts)"));
+    }
+    d->CollisionDetectionStatusLabel->setText(noCollisionsMessage);
     d->CollisionDetectionStatusLabel->setStyleSheet("color: green");
   }
 }