diff --git a/extensions/resteasy-reactive/quarkus-resteasy-reactive/runtime/src/main/java/io/quarkus/resteasy/reactive/server/runtime/QuarkusResteasyReactiveRequestContext.java b/extensions/resteasy-reactive/quarkus-resteasy-reactive/runtime/src/main/java/io/quarkus/resteasy/reactive/server/runtime/QuarkusResteasyReactiveRequestContext.java
index ccc61ff03464c..4496dd8b19f1f 100644
--- a/extensions/resteasy-reactive/quarkus-resteasy-reactive/runtime/src/main/java/io/quarkus/resteasy/reactive/server/runtime/QuarkusResteasyReactiveRequestContext.java
+++ b/extensions/resteasy-reactive/quarkus-resteasy-reactive/runtime/src/main/java/io/quarkus/resteasy/reactive/server/runtime/QuarkusResteasyReactiveRequestContext.java
@@ -14,6 +14,7 @@
 import io.quarkus.security.identity.SecurityIdentity;
 import io.quarkus.vertx.core.runtime.context.VertxContextSafetyToggle;
 import io.quarkus.vertx.http.runtime.security.QuarkusHttpUser;
+import io.smallrye.common.vertx.VertxContext;
 import io.vertx.ext.web.RoutingContext;
 
 public class QuarkusResteasyReactiveRequestContext extends VertxResteasyReactiveRequestContext {
@@ -27,7 +28,9 @@ public QuarkusResteasyReactiveRequestContext(Deployment deployment, ProvidersImp
             CurrentIdentityAssociation currentIdentityAssociation) {
         super(deployment, providers, context, requestContext, handlerChain, abortHandlerChain, devModeTccl);
         this.association = currentIdentityAssociation;
-        VertxContextSafetyToggle.setCurrentContextSafe(true);
+        if (VertxContext.isOnDuplicatedContext()) {
+            VertxContextSafetyToggle.setCurrentContextSafe(true);
+        }
     }
 
     protected void handleRequestScopeActivation() {