diff --git a/meta-oe/recipes-support/libiio/files/0001-python-Do-not-verify-whether-libiio-is-installed-whe.patch b/meta-oe/recipes-support/libiio/files/0001-python-Do-not-verify-whether-libiio-is-installed-whe.patch
new file mode 100644
index 00000000000..4d3dcd5cedd
--- /dev/null
+++ b/meta-oe/recipes-support/libiio/files/0001-python-Do-not-verify-whether-libiio-is-installed-whe.patch
@@ -0,0 +1,34 @@
+From 717b0f46b23ddc042da481d1d446bdd1c6c49142 Mon Sep 17 00:00:00 2001
+From: Julien Malik <julien.malik@unseenlabs.fr>
+Date: Mon, 27 Jul 2020 14:34:44 +0200
+Subject: [PATCH] python: Do not verify whether libiio is installed when
+ cross-compiling
+
+This should fix #561
+
+Signed-off-by: Julien Malik <julien.malik@paraiso.me>
+---
+ bindings/python/setup.py.cmakein | 7 +++++++
+ 1 file changed, 7 insertions(+)
+
+diff --git a/bindings/python/setup.py.cmakein b/bindings/python/setup.py.cmakein
+index cd14e2e..96d58a8 100644
+--- a/bindings/python/setup.py.cmakein
++++ b/bindings/python/setup.py.cmakein
+@@ -54,6 +54,13 @@ class InstallWrapper(install):
+         install.run(self)
+ 
+     def _check_libiio_installed(self):
++        cross_compiling = ("${CMAKE_CROSSCOMPILING}" == "TRUE")
++        if cross_compiling:
++            # When cross-compiling, we generally cannot dlopen
++            # the libiio shared lib from the build platform.
++            # Simply skip this check in that case.
++            return
++
+         from platform import system as _system
+         from ctypes import CDLL as _cdll
+         from ctypes.util import find_library
+-- 
+2.25.1
+
diff --git a/meta-oe/recipes-support/libiio/libiio_git.bb b/meta-oe/recipes-support/libiio/libiio_git.bb
index 00c016db446..d7e4cc60a9f 100644
--- a/meta-oe/recipes-support/libiio/libiio_git.bb
+++ b/meta-oe/recipes-support/libiio/libiio_git.bb
@@ -7,7 +7,9 @@ LIC_FILES_CHKSUM = "file://COPYING.txt;md5=7c13b3376cea0ce68d2d2da0a1b3a72c"
 SRCREV = "565bf68eccfdbbf22cf5cb6d792e23de564665c7"
 PV = "0.21+git${SRCPV}"
 
-SRC_URI = "git://github.com/analogdevicesinc/libiio.git;protocol=https"
+SRC_URI = "git://github.com/analogdevicesinc/libiio.git;protocol=https \
+           file://0001-python-Do-not-verify-whether-libiio-is-installed-whe.patch \
+"
 UPSTREAM_CHECK_GITTAGREGEX = "v(?P<pver>\d+(\.\d+)+)"
 
 S = "${WORKDIR}/git"