diff --git a/packages/react-component-library/src/a11y/storyAccessibilityConfig.ts b/packages/react-component-library/src/a11y/storyAccessibilityConfig.ts
index e8f5d5b148..3102945d09 100644
--- a/packages/react-component-library/src/a11y/storyAccessibilityConfig.ts
+++ b/packages/react-component-library/src/a11y/storyAccessibilityConfig.ts
@@ -15,6 +15,12 @@ export const storyAccessibilityConfig = {
       enabled: false,
     },
   ],
+  'Data Grid': [
+    {
+      id: 'empty-table-header',
+      enabled: false,
+    },
+  ],
   'Date Picker': [
     {
       id: 'aria-required-attr',
diff --git a/packages/react-component-library/src/components/DataGrid/DataGrid.stories.tsx b/packages/react-component-library/src/components/DataGrid/DataGrid.stories.tsx
index f44a7cc6bc..e133be3bb8 100644
--- a/packages/react-component-library/src/components/DataGrid/DataGrid.stories.tsx
+++ b/packages/react-component-library/src/components/DataGrid/DataGrid.stories.tsx
@@ -5,6 +5,7 @@ import { fn } from '@storybook/test'
 import { StoryFn, Meta } from '@storybook/react'
 import { ColumnDef } from '@tanstack/react-table'
 
+import { storyAccessibilityConfig } from '../../a11y/storyAccessibilityConfig'
 import { DataGrid, TABLE_COLUMN_ALIGNMENT } from '.'
 import { Badge } from '../Badge'
 
@@ -15,6 +16,14 @@ type Order = {
   price: string
 }
 
+const disableEmptyTableHeaderRule = {
+  a11y: {
+    config: {
+      rules: storyAccessibilityConfig['Data Grid'],
+    },
+  },
+}
+
 // const generateRandomData = (length: number): Order[] => {
 //   const data: Order[] = Array.from({ length }, (_, i) => {
 //     return {
@@ -321,10 +330,59 @@ ColumnAlignment.args = {
   onSelectedRowsChange: fn(),
 }
 
-const mergedColumns = columns.map((item, index) => ({
-  ...item,
-  ...columnsWithArbitraryContent[index],
-  enableSorting: true,
+const groupedColumns = [
+  {
+    header: 'Group 1',
+    columns: [
+      {
+        header: 'Name',
+        accessorKey: 'productName',
+        enableSorting: false,
+      },
+      {
+        header: 'Price',
+        accessorKey: 'price',
+        enableSorting: false,
+      },
+    ],
+  },
+  {
+    header: 'Group 2',
+    columns: [
+      {
+        header: 'Quantity',
+        accessorKey: 'quantity',
+        enableSorting: false,
+      },
+    ],
+  },
+]
+
+export const ColumnGrouping: StoryFn<typeof DataGrid> = (props) => {
+  return (
+    <Wrapper>
+      <DataGrid {...props} columns={groupedColumns} />
+    </Wrapper>
+  )
+}
+
+ColumnGrouping.storyName = 'Column grouping'
+ColumnGrouping.args = {
+  data,
+  isFullWidth: true,
+  onSelectedRowsChange: fn(),
+}
+
+const mergedColumns = groupedColumns.map((group) => ({
+  ...group,
+  columns: group.columns.map((column) => ({
+    ...column,
+    ...columnsWithArbitraryContent.find(
+      // @ts-ignore
+      (c) => c.accessorKey === column.accessorKey
+    ),
+    enableSorting: true,
+  })),
 }))
 
 export const KitchenSink: StoryFn<typeof DataGrid> = (props) => {
@@ -342,6 +400,7 @@ export const KitchenSink: StoryFn<typeof DataGrid> = (props) => {
 }
 
 KitchenSink.storyName = 'Kitchen sink'
+KitchenSink.parameters = disableEmptyTableHeaderRule
 KitchenSink.args = {
   columns: mergedColumns,
   data,
diff --git a/packages/react-component-library/src/components/DataGrid/DataGrid.test.tsx b/packages/react-component-library/src/components/DataGrid/DataGrid.test.tsx
index aa33391e3e..225d1cf181 100644
--- a/packages/react-component-library/src/components/DataGrid/DataGrid.test.tsx
+++ b/packages/react-component-library/src/components/DataGrid/DataGrid.test.tsx
@@ -488,4 +488,65 @@ describe('DataGrid', () => {
       })
     })
   })
+
+  describe('with column grouping', () => {
+    const columnGroups: ColumnDef<DataRow>[] = [
+      {
+        header: 'Group 1',
+        columns: [
+          {
+            accessorKey: 'first',
+            header: 'First',
+            cell: (info) => info.getValue(),
+            enableSorting: true,
+          },
+          {
+            accessorKey: 'second',
+            header: 'Second',
+            cell: (info) => info.getValue(),
+            enableSorting: false,
+          },
+        ],
+      },
+      {
+        header: 'Group 2',
+        columns: [
+          {
+            accessorKey: 'third',
+            header: 'Third',
+            cell: (info) => info.getValue(),
+            enableSorting: true,
+          },
+        ],
+      },
+    ]
+
+    beforeEach(() => {
+      render(<DataGrid data={data} columns={columnGroups} />)
+    })
+
+    it('should render the column groups correctly', () => {
+      expect(screen.getByText('Group 1')).toBeInTheDocument()
+      expect(screen.getByText('Group 2')).toBeInTheDocument()
+
+      expect(screen.getByText('First')).toBeInTheDocument()
+      expect(screen.getByText('Second')).toBeInTheDocument()
+      expect(screen.getByText('Third')).toBeInTheDocument()
+    })
+
+    it('should render the column groups with the correct order', () => {
+      const firstRow = screen.getAllByRole('row')[0]
+      const firstRowHeaders = within(firstRow).getAllByRole('columnheader')
+
+      expect(firstRowHeaders[0]).toHaveTextContent('Group 1')
+      expect(firstRowHeaders[1]).toHaveTextContent('Group 2')
+
+      const secondRow = screen.getAllByRole('row')[1]
+      const secondRowHeaders = within(secondRow).getAllByRole('columnheader')
+
+      expect(secondRowHeaders[0]).toHaveTextContent('First')
+      expect(secondRowHeaders[1]).toHaveTextContent('Second')
+      expect(secondRowHeaders[2]).toHaveTextContent('Third')
+    })
+  })
 })
diff --git a/packages/react-component-library/src/components/DataGrid/DataGrid.tsx b/packages/react-component-library/src/components/DataGrid/DataGrid.tsx
index a53c235779..fd15bd4c7e 100644
--- a/packages/react-component-library/src/components/DataGrid/DataGrid.tsx
+++ b/packages/react-component-library/src/components/DataGrid/DataGrid.tsx
@@ -1,7 +1,7 @@
 // eslint-disable-next-line @typescript-eslint/triple-slash-reference
 /// <reference path="./DataGrid.d.ts" />
 
-import React, { useState, useEffect } from 'react'
+import React, { useState, useEffect, useMemo } from 'react'
 import _noop from 'lodash/noop'
 import {
   flexRender,
@@ -214,6 +214,12 @@ export const DataGrid = <T extends object>(props: DataGridProps<T>) => {
     )
   }, [rowSelection, table, onSelectedRowsChange])
 
+  const hasGroupedHeaders = useMemo(() => {
+    return table.getHeaderGroups().reduce((acc, group) => {
+      return acc || group.headers.some((header) => header.depth > 1)
+    }, false)
+  }, [table])
+
   return (
     <StyledDataGrid className={className}>
       <StyledTable
@@ -225,7 +231,7 @@ export const DataGrid = <T extends object>(props: DataGridProps<T>) => {
         <StyledHead>
           {table
             .getHeaderGroups()
-            .map(({ id: headerGroupId, headers }: HeaderGroup<T>) => (
+            .map(({ id: headerGroupId, headers, depth }: HeaderGroup<T>) => (
               <StyledRow key={headerGroupId}>
                 {headers.map(
                   ({
@@ -239,14 +245,17 @@ export const DataGrid = <T extends object>(props: DataGridProps<T>) => {
                     id: headerId,
                     isPlaceholder,
                     getContext,
+                    colSpan,
                   }: Header<T, unknown>) => (
                     <StyledCol
                       aria-sort={getAriaSort(getCanSort(), getIsSorted())}
                       $isSortable={getCanSort()}
+                      $isHeaderGroup={hasGroupedHeaders && depth === 0}
                       $alignment={columnDef.meta?.align}
                       $width={getSize() === 150 ? undefined : getSize()}
                       key={headerId}
                       onClick={getToggleSortingHandler()}
+                      colSpan={colSpan}
                     >
                       <div>
                         {isPlaceholder
diff --git a/packages/react-component-library/src/components/DataGrid/partials/StyledCol.tsx b/packages/react-component-library/src/components/DataGrid/partials/StyledCol.tsx
index cb05fa3d86..55a1a9b813 100644
--- a/packages/react-component-library/src/components/DataGrid/partials/StyledCol.tsx
+++ b/packages/react-component-library/src/components/DataGrid/partials/StyledCol.tsx
@@ -7,18 +7,19 @@ interface StyledColProps {
   $isSortable?: boolean
   $alignment?: 'left' | 'right' | 'center'
   $width?: number
+  $isHeaderGroup?: boolean
 }
 
 export const StyledCol = styled.th<StyledColProps>`
   position: relative;
   padding: ${spacing('9')} ${spacing('4')} ${spacing('9')} ${spacing('8')};
   width: ${({ $width }) => $width || 'auto'};
+  border-bottom: 1px solid ${color('neutral', '200')};
+  color: ${color('neutral', '600')};
+  font-weight: 700;
   text-align: left;
+  text-transform: 'capitalize';
   font-size: ${fontSize('s')};
-  color: ${color('neutral', '600')};
-  font-weight: 600;
-  text-transform: capitalize;
-  border-bottom: 1px solid ${color('neutral', '200')};
 
   > div {
     display: flex;
@@ -43,6 +44,18 @@ export const StyledCol = styled.th<StyledColProps>`
     background: ${color('neutral', '200')};
   }
 
+  ${({ $isHeaderGroup }) =>
+    $isHeaderGroup &&
+    css`
+      text-transform: uppercase;
+      font-size: ${fontSize('m')};
+
+      &:not(:last-of-type) > div::after {
+        top: 100%;
+        height: 80px;
+      }
+    `}
+
   ${({ $isSortable }) =>
     $isSortable &&
     css`